STK11 (serine/threonine kinase 11) - Rat Genome Database

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Gene: STK11 (serine/threonine kinase 11) Homo sapiens
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Symbol: STK11
Name: serine/threonine kinase 11
RGD ID: 1318548
HGNC Page HGNC:11389
Description: Enables several functions, including ATP binding activity; magnesium ion binding activity; and p53 binding activity. Involved in several processes, including anoikis; protein phosphorylation; and regulation of signal transduction. Acts upstream of with a negative effect on G1 to G0 transition. Acts upstream of or within activation of protein kinase activity. Located in cytosol; mitochondrion; and nucleoplasm. Part of intracellular protein-containing complex and serine/threonine protein kinase complex. Implicated in Peutz-Jeghers syndrome; cervical mucinous adenocarcinoma; familial melanoma; ovarian carcinoma; and pancreatic cancer. Biomarker of breast carcinoma and endometrial cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: hLKB1; liver kinase B1; LKB1; PJS; polarization-related protein LKB1; renal carcinoma antigen NY-REN-19; serine/threonine kinase 11 (peutz-jeghers syndrome); serine/threonine-protein kinase 11; serine/threonine-protein kinase LKB1; serine/threonine-protein kinase STK11
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38191,205,778 - 1,228,431 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl191,177,558 - 1,228,431 (+)EnsemblGRCh38hg38GRCh38
GRCh37191,205,777 - 1,228,430 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36191,156,798 - 1,179,434 (+)NCBINCBI36Build 36hg18NCBI36
Build 34191,156,797 - 1,179,434NCBI
Celera191,140,029 - 1,162,667 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef19981,572 - 1,004,116 (+)NCBIHuRef
CHM1_1191,205,350 - 1,228,397 (+)NCBICHM1_1
T2T-CHM13v2.0191,174,325 - 1,196,989 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model