IL13 (interleukin 13) - Rat Genome Database

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Gene: IL13 (interleukin 13) Homo sapiens
Analyze
Symbol: IL13
Name: interleukin 13
RGD ID: 69008
HGNC Page HGNC
Description: Predicted to enable cytokine activity and interleukin-13 receptor binding activity. Involved in several processes, including negative regulation of complement-dependent cytotoxicity; negative regulation of endothelial cell apoptotic process; and positive regulation of interleukin-10 production. Located in extracellular region. Implicated in several diseases, including allergic disease (multiple); autoimmune disease (multiple); diffuse scleroderma; lung disease (multiple); and nose disease (multiple). Biomarker of several diseases, including COVID-19; Plasmodium falciparum malaria; autoimmune disease (multiple); lung disease (multiple); and scleroderma (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13; interleukin-13; MGC116786; MGC116788; MGC116789; P600
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,656,263 - 132,661,110 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,656,522 - 132,661,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,992,214 - 131,996,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,021,764 - 132,024,700 (+)NCBINCBI36hg18NCBI36
Build 345132,021,763 - 132,024,700NCBI
Celera5128,123,995 - 128,126,931 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,186,169 - 127,189,105 (+)NCBIHuRef
CHM1_15131,427,162 - 131,430,098 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Lung Injury  (ISO)
alcoholic hepatitis  (ISO)
allergic conjunctivitis  (IAGP,IEP)
allergic disease  (EXP,IAGP)
allergic rhinitis  (EXP,IAGP)
asthma  (EXP,IAGP,IEP,ISO)
atopic dermatitis  (EXP,IAGP,IEP,ISO)
autistic disorder  (EXP)
autoimmune hepatitis  (EXP)
Breast Neoplasms  (IAGP,IMP)
Bronchial Hyperreactivity  (EXP,IAGP,ISO)
bronchiolitis obliterans  (IEP,ISO)
chlamydia  (ISO)
Chronic Bronchitis  (IEP)
chronic obstructive pulmonary disease  (IAGP)
contact dermatitis  (ISO)
COVID-19  (IEP)
cutaneous leishmaniasis  (ISO)
cystic fibrosis  (IEP)
Delayed Hypersensitivity  (ISO)
dermatitis  (EXP,IAGP)
diffuse scleroderma  (IAGP)
drug allergy  (EXP)
Eczema  (IAGP)
egg allergy  (IAGP)
Endotoxemia  (IDA)
esophagitis  (ISO)
Experimental Arthritis  (EXP,IDA,ISO)
Experimental Autoimmune Encephalomyelitis  (IMP,ISO)
Experimental Autoimmune Myocarditis  (ISO)
extrinsic allergic alveolitis  (ISO)
familial adenomatous polyposis 1  (IAGP)
Fibrosis  (ISO)
food allergy  (ISO)
Fungal Lung Diseases  (ISO)
Graves' disease  (IAGP)
hepatitis C  (IEP)
Hereditary Neoplastic Syndromes  (IAGP)
Human Influenza  (IEP)
Hyperalgesia  (IDA)
Hyperplasia  (EXP)
Immediate Hypersensitivity  (EXP)
Inflammation  (EXP)
invasive ductal carcinoma  (IEP)
Kawasaki disease  (ISO)
lipoid nephrosis  (ISO)
localized scleroderma  (IEP)
lung disease  (EXP,IEP,ISO)
Lymphatic Metastasis  (IEP)
mastocytosis  (IAGP)
Metaplasia  (EXP)
middle cerebral artery infarction  (ISO)
milk allergy  (IAGP)
multiple sclerosis  (IEP)
Mycoplasma pneumoniae pneumonia  (IEP)
Nasal Polyps  (IEP)
Neurodevelopmental Disorders  (IAGP)
non-alcoholic fatty liver disease  (IEP)
occupational dermatitis  (ISO)
onchocerciasis  (IEP)
ovarian carcinoma  (IEP)
pancreatic cancer  (IEP,IMP)
pancreatitis  (IEP,ISO)
peanut allergy  (IAGP)
peptic esophagitis  (ISO)
Perennial Allergic Rhinitis  (IEP)
Picornaviridae Infections  (ISO)
Plasmodium falciparum malaria  (IEP)
pneumonia  (EXP,IEP)
prostatic hypertrophy  (ISO)
Pseudomonas Infections  (IEP)
psoriasis  (EXP,IAGP)
psoriatic arthritis  (IAGP)
pulmonary edema  (IDA)
pulmonary emphysema  (ISO)
pulmonary eosinophilia  (ISO)
pulmonary fibrosis  (EXP,IEP,ISO)
pulmonary hypertension  (IEP)
pulmonary tuberculosis  (IEP)
purpura  (IAGP)
Radiation Pneumonitis  (IAGP)
renal cell carcinoma  (EXP)
Reperfusion Injury  (IDA,ISO)
respiratory allergy  (IAGP,ISO)
Respiratory Sounds  (IEP)
respiratory syncytial virus infectious disease  (ISO)
Respiratory Tract Granuloma  (ISO)
Respiratory Tract Infections  (IEP)
rheumatoid arthritis  (IEP)
rhinitis  (IAGP,ISO)
Schistosomiasis Mansoni  (ISO)
Sepsis  (ISO)
sinusitis  (EXP,IAGP)
Sjogren's syndrome  (IEP)
systemic lupus erythematosus  (IEP)
systemic scleroderma  (IAGP,IEP,ISO)
T-Cell Lymphoma  (ISO)
Transplant Rejection  (IMP,ISO)
uveitis  (IDA)
vitiligo  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-tolyl isocyanate  (ISO)
9-cis-retinoic acid  (EXP)
abacavir  (EXP)
acetone  (EXP)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (EXP)
alpha-galactosylceramide  (ISO)
aluminium hydroxide  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antigen  (EXP,ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
beclomethasone  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzofurans  (ISO)
benzyl isothiocyanate  (EXP)
beta-naphthoflavone  (ISO)
bis(2-chloroethyl) sulfide  (EXP,ISO)
bisphenol A  (ISO)
bleomycin A2  (ISO)
Brevetoxin B  (EXP)
bucladesine  (EXP)
budesonide  (EXP)
butanal  (EXP)
C.I. Natural Red 20  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
Calcimycin  (EXP,ISO)
calcipotriol  (ISO)
calcitriol  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
capsaicin  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (EXP,ISO)
ceric oxide  (ISO)
chlorobenzene  (EXP)
chloroform  (ISO)
chloroquine  (ISO)
chlorpyrifos  (EXP)
choline  (ISO)
clopidogrel  (ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
D-penicillamine  (ISO)
Deguelin  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dichlorine  (ISO)
dicyclohexylmethane-4,4'-diisocyanate  (ISO)
diisononyl phthalate  (ISO)
diphenylmethane-4,4'-diisocyanate  (ISO)
donepezil hydrochloride  (ISO)
emodin  (ISO)
epinastine  (EXP)
etazolate  (EXP)
ethambutol  (EXP)
ethene  (ISO)
Fidarestat  (EXP,ISO)
fisetin  (EXP)
formaldehyde  (ISO)
formoterol fumarate  (ISO)
fragrance  (EXP)
gadodiamide hydrate  (EXP)
gadolinium trichloride  (EXP)
gemcitabine  (EXP)
genistein  (ISO)
gentamycin  (ISO)
glutathione  (EXP)
glyphosate  (ISO)
graphite  (ISO)
hexamethylene diisocyanate  (ISO)
hydrogen peroxide  (EXP)
hydroxyurea  (ISO)
ilomastat  (ISO)
ionomycin  (ISO)
isophorone diisocyanate  (ISO)
lactacystin  (ISO)
leflunomide  (EXP)
leukotriene B4  (ISO)
leukotriene C4  (ISO)
leukotriene D4  (ISO)
leukotriene E4  (ISO)
lidocaine  (ISO)
linuron  (ISO)
lipopolysaccharide  (EXP,ISO)
luteolin  (ISO)
mercury dichloride  (ISO)
metformin  (ISO)
methotrexate  (EXP,ISO)
methoxychlor  (ISO)
MK 571  (ISO)
montelukast  (ISO)
morphine  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-acetyl-L-cysteine  (EXP)
N-ethyl-5'-carboxamidoadenosine  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
naproxen  (ISO)
nickel atom  (EXP,ISO)
nickel dichloride  (ISO)
nitrogen dioxide  (EXP,ISO)
nitrososulfamethoxazole  (EXP)
ochratoxin A  (EXP)
organophosphorus compound  (EXP)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (ISO)
patulin  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phosmet  (EXP)
phthalaldehyde  (ISO)
phthalic anhydride  (EXP,ISO)
pioglitazone  (ISO)
piperonyl butoxide  (ISO)
polymyxin B2  (ISO)
pomalidomide  (EXP)
prednisolone  (ISO)
prednisone  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
prostaglandin E2  (EXP)
pyocyanine  (ISO)
quercetin  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (EXP)
rolipram  (EXP)
serotonin  (ISO)
serpentine asbestos  (ISO)
Shikonin  (ISO)
silicon dioxide  (EXP)
simvastatin  (ISO)
sodium arsenite  (EXP)
sterigmatocystin  (ISO)
sulfur dioxide  (ISO)
sumatriptan  (ISO)
sunitinib  (EXP)
syringin  (ISO)
Terfenadine  (EXP)
tetrachloromethane  (ISO)
theophylline  (EXP)
thimerosal  (EXP)
thioacetamide  (EXP)
titanium dioxide  (EXP,ISO)
toluene 2,4-diisocyanate  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
triclosan  (EXP)
trimellitic anhydride  (ISO)
valproic acid  (EXP)
zearalenone  (EXP)
zileuton  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular response to cytokine stimulus  (IEA,ISO)
cellular response to mechanical stimulus  (IEA,ISO)
immune response  (IEA)
inflammatory response  (IEA,ISO)
macrophage activation  (IGI)
microglial cell activation  (IEA,ISO)
negative regulation of complement-dependent cytotoxicity  (IMP)
negative regulation of endothelial cell apoptotic process  (IMP)
negative regulation of inflammatory response  (IGI)
negative regulation of lung ciliated cell differentiation  (NAS)
negative regulation of NAD(P)H oxidase activity  (IEA,ISO)
negative regulation of neuron death  (IEA,ISO)
negative regulation of transforming growth factor beta production  (IEA,ISO)
positive regulation of B cell proliferation  (IEA,ISO)
positive regulation of cold-induced thermogenesis  (ISS)
positive regulation of connective tissue growth factor production  (IEA,ISO)
positive regulation of gene expression  (IGI,ISS)
positive regulation of immunoglobulin production  (IEA,ISO)
positive regulation of interleukin-10 production  (IGI)
positive regulation of ion transport  (ISO)
positive regulation of lung goblet cell differentiation  (NAS)
positive regulation of macrophage activation  (IEA)
positive regulation of mast cell degranulation  (IEA,ISO)
positive regulation of pancreatic stellate cell proliferation  (IEA,ISO)
positive regulation of protein secretion  (IEA,ISO)
positive regulation of release of sequestered calcium ion into cytosol  (IEA,ISO)
positive regulation of smooth muscle cell proliferation  (IEA,ISO)
positive regulation of tyrosine phosphorylation of STAT protein  (IEA,ISO)
regulation of proton transport  (IEA,ISO)
response to ethanol  (IEA,ISO)
response to lipopolysaccharide  (IEA,ISO)
response to mechanical stimulus  (ISO)
response to nicotine  (IEA,ISO)
signal transduction  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
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Additional References at PubMed
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PMID:11396683   PMID:11709756   PMID:11786536   PMID:11825773   PMID:11830476   PMID:11940068   PMID:11980568   PMID:12063528   PMID:12067309   PMID:12089333   PMID:12089714   PMID:12097410  
PMID:12145428   PMID:12152987   PMID:12163193   PMID:12165514   PMID:12189139   PMID:12207328   PMID:12223527   PMID:12370393   PMID:12370400   PMID:12377947   PMID:12396617   PMID:12413765  
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PMID:34185704   PMID:34290170  


Genomics

Comparative Map Data
IL13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5132,656,263 - 132,661,110 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,656,522 - 132,661,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,992,214 - 131,996,802 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,021,764 - 132,024,700 (+)NCBINCBI36hg18NCBI36
Build 345132,021,763 - 132,024,700NCBI
Celera5128,123,995 - 128,126,931 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,186,169 - 127,189,105 (+)NCBIHuRef
CHM1_15131,427,162 - 131,430,098 (+)NCBICHM1_1
Il13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391153,522,150 - 53,525,529 (-)NCBIGRCm39mm39
GRCm39 Ensembl1153,522,151 - 53,525,529 (-)Ensembl
GRCm381153,631,323 - 53,634,702 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1153,631,324 - 53,634,702 (-)EnsemblGRCm38mm10GRCm38
MGSCv371153,444,825 - 53,448,204 (-)NCBIGRCm37mm9NCBIm37
MGSCv361153,474,747 - 53,478,125 (-)NCBImm8
Celera1158,210,849 - 58,214,228 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1131.98NCBI
Il13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21037,790,130 - 37,792,687 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1037,790,130 - 37,792,737 (-)Ensembl
Rnor_6.01038,982,909 - 38,985,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1038,982,909 - 38,985,466 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01038,764,639 - 38,767,196 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41039,093,512 - 39,096,069 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11039,102,758 - 39,105,316 (-)NCBI
Celera1037,134,342 - 37,136,897 (-)NCBICelera
Cytogenetic Map10q22NCBI
Il13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554084,046,406 - 4,049,795 (+)NCBIChiLan1.0ChiLan1.0
IL13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15134,235,788 - 134,240,548 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5134,235,788 - 134,240,548 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05128,073,863 - 128,078,453 (+)NCBIMhudiblu_PPA_v0panPan3
IL13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11120,957,870 - 20,961,391 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1120,958,464 - 20,961,388 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1119,759,917 - 19,762,847 (+)NCBI
ROS_Cfam_1.01121,744,389 - 21,747,318 (+)NCBI
UMICH_Zoey_3.11120,462,871 - 20,465,798 (+)NCBI
UNSW_CanFamBas_1.01120,310,464 - 20,313,371 (+)NCBI
UU_Cfam_GSD_1.01120,952,917 - 20,955,847 (+)NCBI
Il13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213115,527,018 - 115,529,671 (-)NCBI
SpeTri2.0NW_0049366472,529,933 - 2,532,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2134,972,623 - 134,975,093 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12134,972,099 - 134,976,672 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22140,441,025 - 140,444,068 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IL13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12335,475,762 - 35,479,419 (+)NCBI
ChlSab1.1 Ensembl2335,476,490 - 35,478,869 (+)Ensembl
Vero_WHO_p1.0NW_02366603442,463,847 - 42,466,277 (-)NCBI
Il13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473339,427,189 - 39,430,019 (-)NCBI

Position Markers
D4S2394  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374130,297,833 - 130,298,080UniSTSGRCh37
Build 364130,517,283 - 130,517,530RGDNCBI36
Celera4127,679,285 - 127,679,525RGD
HuRef4126,028,047 - 126,028,288UniSTS
deCODE Assembly Map4128.08UniSTS
D4S1651  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh374112,132,472 - 112,132,671UniSTSGRCh37
Build 364112,351,921 - 112,352,120RGDNCBI36
Celera4109,425,906 - 109,426,105RGD
HuRef4107,863,843 - 107,864,042UniSTS
Marshfield Genetic Map4117.06RGD
Marshfield Genetic Map4117.06UniSTS
deCODE Assembly Map4115.68UniSTS
Whitehead-RH Map4570.0UniSTS
Whitehead-YAC Contig Map4 UniSTS
D5S2410  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,394 - 131,996,736UniSTSGRCh37
Build 365132,024,293 - 132,024,635RGDNCBI36
Celera5128,126,524 - 128,126,866RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,698 - 127,189,040UniSTS
Stanford-G3 RH Map54975.0UniSTS
GeneMap99-GB4 RH Map5510.1UniSTS
Whitehead-RH Map5415.5UniSTS
Whitehead-YAC Contig Map5 UniSTS
GeneMap99-G3 RH Map55063.0UniSTS
PMC356970P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,120 - 131,996,102UniSTSGRCh37
Build 365132,023,019 - 132,024,001RGDNCBI36
Celera5128,125,250 - 128,126,232RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,424 - 127,188,406UniSTS
IL13_148  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,064 - 131,996,838UniSTSGRCh37
Build 365132,023,963 - 132,024,737RGDNCBI36
Celera5128,126,194 - 128,126,968RGD
HuRef5127,188,368 - 127,189,142UniSTS
ECD00324  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,774 - 131,995,687UniSTSGRCh37
Build 365132,022,673 - 132,023,586RGDNCBI36
Celera5128,124,904 - 128,125,817RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,078 - 127,187,991UniSTS
ECD05278  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,270 - 131,993,010UniSTSGRCh37
Build 365132,020,169 - 132,020,909RGDNCBI36
Celera5128,122,400 - 128,123,140RGD
Cytogenetic Map5q31UniSTS
HuRef5127,184,574 - 127,185,314UniSTS
ECD09780  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,539 - 131,997,159UniSTSGRCh37
Build 365132,024,438 - 132,025,058RGDNCBI36
Celera5128,126,669 - 128,127,289RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,843 - 127,189,463UniSTS
ECD09846  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,829 - 131,996,447UniSTSGRCh37
Build 365132,023,728 - 132,024,346RGDNCBI36
Celera5128,125,959 - 128,126,577RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,133 - 127,188,751UniSTS
ECD09979  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,223 - 131,993,837UniSTSGRCh37
Build 365132,021,122 - 132,021,736RGDNCBI36
Celera5128,123,353 - 128,123,967RGD
Cytogenetic Map5q31UniSTS
HuRef5127,185,527 - 127,186,141UniSTS
ECD10847  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,895 - 131,994,484UniSTSGRCh37
Build 365132,021,794 - 132,022,383RGDNCBI36
Celera5128,124,025 - 128,124,614RGD
Cytogenetic Map5q31UniSTS
HuRef5127,186,199 - 127,186,788UniSTS
REN71151  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,024 - 131,992,289UniSTSGRCh37
Build 365132,019,923 - 132,020,188RGDNCBI36
Celera5128,122,154 - 128,122,419RGD
Cytogenetic Map5q31UniSTS
HuRef5127,184,328 - 127,184,593UniSTS
REN71152  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,269 - 131,992,497UniSTSGRCh37
Build 365132,020,168 - 132,020,396RGDNCBI36
Celera5128,122,399 - 128,122,627RGD
Cytogenetic Map5q31UniSTS
HuRef5127,184,573 - 127,184,801UniSTS
REN71153  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,422 - 131,992,670UniSTSGRCh37
Build 365132,020,321 - 132,020,569RGDNCBI36
Celera5128,122,552 - 128,122,800RGD
Cytogenetic Map5q31UniSTS
HuRef5127,184,726 - 127,184,974UniSTS
REN71154  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,668 - 131,992,904UniSTSGRCh37
Build 365132,020,567 - 132,020,803RGDNCBI36
Celera5128,122,798 - 128,123,034RGD
Cytogenetic Map5q31UniSTS
HuRef5127,184,972 - 127,185,208UniSTS
REN71155  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,880 - 131,993,105UniSTSGRCh37
Build 365132,020,779 - 132,021,004RGDNCBI36
Celera5128,123,010 - 128,123,235RGD
Cytogenetic Map5q31UniSTS
HuRef5127,185,184 - 127,185,409UniSTS
REN71156  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,073 - 131,993,339UniSTSGRCh37
Build 365132,020,972 - 132,021,238RGDNCBI36
Celera5128,123,203 - 128,123,469RGD
Cytogenetic Map5q31UniSTS
HuRef5127,185,377 - 127,185,643UniSTS
REN71157  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,318 - 131,993,572UniSTSGRCh37
Build 365132,021,217 - 132,021,471RGDNCBI36
Celera5128,123,448 - 128,123,702RGD
Cytogenetic Map5q31UniSTS
HuRef5127,185,622 - 127,185,876UniSTS
REN71158  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,550 - 131,993,795UniSTSGRCh37
Build 365132,021,449 - 132,021,694RGDNCBI36
Celera5128,123,680 - 128,123,925RGD
Cytogenetic Map5q31UniSTS
HuRef5127,185,854 - 127,186,099UniSTS
REN71159  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,993,769 - 131,994,016UniSTSGRCh37
Build 365132,021,668 - 132,021,915RGDNCBI36
Celera5128,123,899 - 128,124,146RGD
Cytogenetic Map5q31UniSTS
HuRef5127,186,073 - 127,186,320UniSTS
REN71160  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,014 - 131,994,252UniSTSGRCh37
Build 365132,021,913 - 132,022,151RGDNCBI36
Celera5128,124,144 - 128,124,382RGD
Cytogenetic Map5q31UniSTS
HuRef5127,186,318 - 127,186,556UniSTS
REN71161  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,224 - 131,994,482UniSTSGRCh37
Build 365132,022,123 - 132,022,381RGDNCBI36
Celera5128,124,354 - 128,124,612RGD
Cytogenetic Map5q31UniSTS
HuRef5127,186,528 - 127,186,786UniSTS
REN71162  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,459 - 131,994,722UniSTSGRCh37
Build 365132,022,358 - 132,022,621RGDNCBI36
Celera5128,124,589 - 128,124,852RGD
Cytogenetic Map5q31UniSTS
HuRef5127,186,763 - 127,187,026UniSTS
REN71163  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,708 - 131,994,963UniSTSGRCh37
Build 365132,022,607 - 132,022,862RGDNCBI36
Celera5128,124,838 - 128,125,093RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,012 - 127,187,267UniSTS
REN71164  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,941 - 131,995,181UniSTSGRCh37
Build 365132,022,840 - 132,023,080RGDNCBI36
Celera5128,125,071 - 128,125,311RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,245 - 127,187,485UniSTS
REN71165  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,156 - 131,995,419UniSTSGRCh37
Build 365132,023,055 - 132,023,318RGDNCBI36
Celera5128,125,286 - 128,125,549RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,460 - 127,187,723UniSTS
REN71166  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,399 - 131,995,625UniSTSGRCh37
Build 365132,023,298 - 132,023,524RGDNCBI36
Celera5128,125,529 - 128,125,755RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,703 - 127,187,929UniSTS
REN71167  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,596 - 131,995,855UniSTSGRCh37
Build 365132,023,495 - 132,023,754RGDNCBI36
Celera5128,125,726 - 128,125,985RGD
Cytogenetic Map5q31UniSTS
HuRef5127,187,900 - 127,188,159UniSTS
REN71168  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,852 - 131,996,105UniSTSGRCh37
Build 365132,023,751 - 132,024,004RGDNCBI36
Celera5128,125,982 - 128,126,235RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,156 - 127,188,409UniSTS
REN71169  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,082 - 131,996,338UniSTSGRCh37
Build 365132,023,981 - 132,024,237RGDNCBI36
Celera5128,126,212 - 128,126,468RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,386 - 127,188,642UniSTS
REN71170  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,316 - 131,996,556UniSTSGRCh37
Build 365132,024,215 - 132,024,455RGDNCBI36
Celera5128,126,446 - 128,126,686RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,620 - 127,188,860UniSTS
REN71171  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,538 - 131,996,795UniSTSGRCh37
Build 365132,024,437 - 132,024,694RGDNCBI36
Celera5128,126,668 - 128,126,925RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,842 - 127,189,099UniSTS
REN71172  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,773 - 131,997,018UniSTSGRCh37
Build 365132,024,672 - 132,024,917RGDNCBI36
Celera5128,126,903 - 128,127,148RGD
Cytogenetic Map5q31UniSTS
HuRef5127,189,077 - 127,189,322UniSTS
REN71173  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,990 - 131,997,236UniSTSGRCh37
Build 365132,024,889 - 132,025,135RGDNCBI36
Celera5128,127,120 - 128,127,366RGD
Cytogenetic Map5q31UniSTS
HuRef5127,189,294 - 127,189,540UniSTS
stSG601426  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,992,622 - 131,994,068UniSTSGRCh37
Build 365132,020,521 - 132,021,967RGDNCBI36
Celera5128,122,752 - 128,124,198RGD
HuRef5127,184,926 - 127,186,372UniSTS
stSG601427  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,994,070 - 131,995,267UniSTSGRCh37
Build 365132,021,969 - 132,023,166RGDNCBI36
Celera5128,124,200 - 128,125,397RGD
HuRef5127,186,374 - 127,187,571UniSTS
stSG601428  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,995,352 - 131,996,446UniSTSGRCh37
Build 365132,023,251 - 132,024,345RGDNCBI36
Celera5128,125,482 - 128,126,576RGD
HuRef5127,187,656 - 127,188,750UniSTS
stSG601429  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375131,996,433 - 131,996,652UniSTSGRCh37
Build 365132,024,332 - 132,024,551RGDNCBI36
Celera5128,126,563 - 128,126,782RGD
Cytogenetic Map5q31UniSTS
HuRef5127,188,737 - 127,188,956UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR98hsa-miR-98-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
MIR98hsa-miR-98-3pTarbaseexternal_infoOtherNEGATIVE
MIRLET7Dhsa-let-7d-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
MIRLET7Dhsa-let-7d-5pTarbaseexternal_infoReporter GenePOSITIVE
MIRLET7Dhsa-let-7d-5pTarbaseexternal_infoOtherPOSITIVE
MIRLET7F1hsa-let-7f-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
MIRLET7F1hsa-let-7f-5pTarbaseexternal_infoReporter GenePOSITIVE
MIRLET7F1hsa-let-7f-5pTarbaseexternal_infoOtherPOSITIVE
MIRLET7F2hsa-let-7f-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
MIRLET7F2hsa-let-7f-5pTarbaseexternal_infoReporter GenePOSITIVE
MIRLET7F2hsa-let-7f-5pTarbaseexternal_infoOtherPOSITIVE
MIRLET7Ihsa-let-7i-5pTarbaseexternal_infoReporter GenePOSITIVE
MIRLET7Ihsa-let-7i-5pTarbaseexternal_infoOtherPOSITIVE
MIRLET7Ghsa-let-7g-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524
MIRLET7Ghsa-let-7g-5pTarbaseexternal_infoOtherPOSITIVE
MIRLET7Ihsa-let-7i-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI21616524

Predicted Target Of
Summary Value
Count of predictions:1344
Count of miRNA genes:675
Interacting mature miRNAs:775
Transcripts:ENST00000304506, ENST00000459878, ENST00000462480, ENST00000468334, ENST00000487267
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage
High
Medium 6 352 1
Low 70 93 18 7 399 7 212 68 102 6 58 82 1 76 150
Below cutoff 1656 1783 971 286 890 195 3140 1510 3146 142 699 905 94 916 2158

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354991 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001354993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC004039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF043334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF172149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF172150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF193838 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF193839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF193840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF377331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF416600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY008331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY008332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096138 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096141 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573912 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L06801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L13029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L42079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L42080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC461686 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U10307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U31120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X69079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000304506   ⟹   ENSP00000304915
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,658,173 - 132,661,110 (+)Ensembl
RefSeq Acc Id: ENST00000459878
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,656,524 - 132,660,614 (+)Ensembl
RefSeq Acc Id: ENST00000462480
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,658,173 - 132,660,332 (+)Ensembl
RefSeq Acc Id: ENST00000468334
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,656,263 - 132,660,550 (+)Ensembl
RefSeq Acc Id: ENST00000487267
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,656,536 - 132,660,703 (+)Ensembl
RefSeq Acc Id: ENST00000617259   ⟹   ENSP00000479835
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5132,658,173 - 132,660,328 (+)Ensembl
RefSeq Acc Id: NM_001354991   ⟹   NP_001341920
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,656,522 - 132,661,110 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354992   ⟹   NP_001341921
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,656,522 - 132,661,110 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001354993   ⟹   NP_001341922
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,656,522 - 132,661,110 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002188   ⟹   NP_002179
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,658,173 - 132,661,110 (+)NCBI
GRCh375131,993,865 - 131,996,801 (+)ENTREZGENE
Build 365132,021,764 - 132,024,700 (+)NCBI Archive
HuRef5127,186,169 - 127,189,105 (+)ENTREZGENE
CHM1_15131,427,162 - 131,430,098 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002179   ⟸   NM_002188
- Peptide Label: isoform 1 precursor
- UniProtKB: P35225 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001341921   ⟸   NM_001354992
- Peptide Label: isoform b
- Sequence:
RefSeq Acc Id: NP_001341922   ⟸   NM_001354993
- Peptide Label: isoform b
- Sequence:
RefSeq Acc Id: NP_001341920   ⟸   NM_001354991
- Peptide Label: isoform b
- Sequence:
RefSeq Acc Id: ENSP00000479835   ⟸   ENST00000617259
RefSeq Acc Id: ENSP00000304915   ⟸   ENST00000304506

Promoters
RGD ID:6802795
Promoter ID:HG_KWN:51060
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   Lymphoblastoid
Transcripts:OTTHUMT00000132565,   OTTHUMT00000132779,   OTTHUMT00000132783,   OTTHUMT00000132784,   OTTHUMT00000132785
Position:
Human AssemblyChrPosition (strand)Source
Build 365132,019,566 - 132,020,207 (-)MPROMDB
RGD ID:6803266
Promoter ID:HG_KWN:51061
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell
Transcripts:OTTHUMT00000132782,   OTTHUMT00000315744
Position:
Human AssemblyChrPosition (strand)Source
Build 365132,021,826 - 132,023,027 (+)MPROMDB
RGD ID:6870542
Promoter ID:EPDNEW_H8436
Type:single initiation site
Name:IL13_1
Description:interleukin 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385132,658,173 - 132,658,233EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
IL13, -1112C-T, PROMOTER single nucleotide variant Asthma, susceptibility to [RCV000015784] Chr5:5q31 risk factor
NM_002188.3(IL13):c.431A>G (p.Gln144Arg) single nucleotide variant Allergic rhinitis, susceptibility to [RCV000015786]|Asthma, susceptibility to [RCV000015785] Chr5:132660272 [GRCh38]
Chr5:131995964 [GRCh37]
Chr5:5q31.1
risk factor
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q23.2-31.1(chr5:126438406-132873967)x1 copy number loss See cases [RCV000052109] Chr5:126438406..132873967 [GRCh38]
Chr5:125774098..132209659 [GRCh37]
Chr5:125801997..132237558 [NCBI36]
Chr5:5q23.2-31.1
pathogenic
GRCh38/hg38 5q31.1(chr5:132301874-134187817)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053312]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053312]|See cases [RCV000053312] Chr5:132301874..134187817 [GRCh38]
Chr5:131637567..133523508 [GRCh37]
Chr5:131665466..133551407 [NCBI36]
Chr5:5q31.1
uncertain significance
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
GRCh38/hg38 5q23.1-31.1(chr5:116677122-132686163)x1 copy number loss See cases [RCV000053525] Chr5:116677122..132686163 [GRCh38]
Chr5:116012818..132021855 [GRCh37]
Chr5:116040717..132049754 [NCBI36]
Chr5:5q23.1-31.1
pathogenic
NM_002188.2(IL13):c.176C>T (p.Ala59Val) single nucleotide variant Malignant melanoma [RCV000061106] Chr5:132659419 [GRCh38]
Chr5:131995111 [GRCh37]
Chr5:132023010 [NCBI36]
Chr5:5q31.1
not provided
GRCh38/hg38 5q31.1(chr5:131626503-135815054)x1 copy number loss See cases [RCV000135442] Chr5:131626503..135815054 [GRCh38]
Chr5:130962196..135150743 [GRCh37]
Chr5:130990095..135178642 [NCBI36]
Chr5:5q31.1
pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV001381154]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q31.1(chr5:131484039-132998360)x3 copy number gain Blepharophimosis [RCV000677199] Chr5:131484039..132998360 [GRCh37]
Chr5:5q31.1
uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q23.2-31.2(chr5:126377719-136270989)x1 copy number loss not provided [RCV000762739] Chr5:126377719..136270989 [GRCh37]
Chr5:5q23.2-31.2
likely pathogenic
NM_002188.3(IL13):c.153C>A (p.Val51=) single nucleotide variant not provided [RCV000966959] Chr5:132658339 [GRCh38]
Chr5:131994031 [GRCh37]
Chr5:5q31.1
benign
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:5973 AgrOrtholog
COSMIC IL13 COSMIC
Ensembl Genes ENSG00000169194 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000304915 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000479835 UniProtKB/TrEMBL
Ensembl Transcript ENST00000304506 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000617259 UniProtKB/TrEMBL
GTEx ENSG00000169194 GTEx
HGNC ID HGNC:5973 ENTREZGENE
Human Proteome Map IL13 Human Proteome Map
InterPro 4_helix_cytokine-like_core UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-4/IL-13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IL-4/IL-13_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:3596 UniProtKB/Swiss-Prot
NCBI Gene 3596 ENTREZGENE
OMIM 147683 OMIM
  600807 OMIM
  607154 OMIM
Pfam IL13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB IL13 RGD, PharmGKB
PRINTS INTRLEUKIN13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE INTERLEUKIN_4_13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IL4_13 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A087WW07_HUMAN UniProtKB/TrEMBL
  D3DQ88_HUMAN UniProtKB/TrEMBL
  IL13_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q4VB50_HUMAN UniProtKB/TrEMBL
  Q4VB51_HUMAN UniProtKB/TrEMBL
  Q4VB53_HUMAN UniProtKB/TrEMBL
UniProt Secondary O43644 UniProtKB/Swiss-Prot
  Q4VB52 UniProtKB/Swiss-Prot
  Q9UDC7 UniProtKB/Swiss-Prot