Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: IL13 (interleukin 13) Homo sapiens
Analyze
Symbol: IL13
Name: interleukin 13
Description: Predicted to have cytokine activity and interleukin-13 receptor binding activity. Involved in several processes, including negative regulation of complement-dependent cytotoxicity; negative regulation of endothelial cell apoptotic process; and positive regulation of interleukin-10 secretion. Localizes to extracellular region. Implicated in several diseases, including allergic hypersensitivity disease (multiple); autoimmune hypersensitivity disease (multiple); dermatitis (multiple); lung disease (multiple); and nose disease (multiple). Biomarker of several diseases, including Plasmodium falciparum malaria; autoimmune hypersensitivity disease (multiple); cystic fibrosis; invasive ductal carcinoma; and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: allergic rhinitis; ALRH; BHR1; Bronchial hyperresponsiveness-1 (bronchial asthma); IL-13; interleukin-13; MGC116786; MGC116788; MGC116789; P600
Orthologs:
Mus musculus (house mouse) : Il13 (interleukin 13)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il13 (interleukin 13)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il13 (interleukin 13)
Pan paniscus (bonobo/pygmy chimpanzee) : IL13 (interleukin 13)
Canis lupus familiaris (dog) : IL13 (interleukin 13)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il13 (interleukin 13)
Sus scrofa (pig) : IL13 (interleukin 13)
Chlorocebus sabaeus (African green monkey) : IL13 (interleukin 13)
Heterocephalus glaber (naked mole-rat) : Il13 (interleukin 13)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl5132,656,263 - 132,661,110 (+)EnsemblGRCh38hg38GRCh38
GRCh385132,656,522 - 132,661,110 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh375131,993,865 - 131,996,801 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365132,021,764 - 132,024,700 (+)NCBINCBI36hg18NCBI36
Build 345132,021,763 - 132,024,700NCBI
Celera5128,123,995 - 128,126,931 (+)NCBI
Cytogenetic Map5q31.1NCBI
HuRef5127,186,169 - 127,189,105 (+)NCBIHuRef
CHM1_15131,427,162 - 131,430,098 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on IL13
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69008
Created: 2001-11-06
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.