CASP9 (caspase 9) - Rat Genome Database

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Gene: CASP9 (caspase 9) Homo sapiens
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Symbol: CASP9
Name: caspase 9
RGD ID: 69147
HGNC Page HGNC
Description: Exhibits several functions, including SH3 domain binding activity; cysteine-type endopeptidase activity involved in apoptotic signaling pathway; and identical protein binding activity. Involved in several processes, including cellular response to UV; intracellular signal transduction; and regulation of response to DNA damage stimulus. Localizes to apoptosome. Implicated in several diseases, including Parkinson's disease; colorectal cancer; lung non-small cell carcinoma; pancreatic cancer; and type 2 diabetes mellitus. Biomarker of several diseases, including diabetic retinopathy; lung non-small cell carcinoma; neurodegenerative disease (multiple); severe acute respiratory syndrome; and type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: APAF-3; APAF3; apoptotic protease activating factor 3; apoptotic protease MCH-6; apoptotic protease-activating factor 3; CASP-9; caspase 9, apoptosis-related cysteine peptidase; caspase 9, apoptosis-related cysteine protease; caspase-9; CASPASE-9c; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1, regulatory subunit 56
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl115,490,832 - 15,526,534 (-)EnsemblGRCh38hg38GRCh38
GRCh38115,491,401 - 15,524,912 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37115,817,896 - 15,851,285 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36115,691,378 - 15,723,377 (-)NCBINCBI36hg18NCBI36
Build 34115,564,102 - 15,596,096NCBI
Celera114,301,661 - 14,333,662 (-)NCBI
Cytogenetic Map1p36.21NCBI
HuRef114,337,387 - 14,370,798 (-)NCBIHuRef
CHM1_1115,616,531 - 15,649,948 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model