CCN2 Human (+)-beta-thujone multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human (+)-catechin multiple interactions EXP 6480464 [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of CCN2 mRNA CTD PMID:24763279 CCN2 Human (-)-epigallocatechin 3-gallate affects expression ISO Ccn2 (Mus musculus) 6480464 epigallocatechin gallate affects the expression of CCN2 CTD PMID:25955525 CCN2 Human (20S)-ginsenoside Rg3 decreases expression EXP 6480464 ginsenoside Rg3 results in decreased expression of CCN2 mRNA CTD PMID:31916386 CCN2 Human (R)-camphor multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human (R)-carnitine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] CTD PMID:26581635 CCN2 Human (R)-linalyl acetate multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human (S)-nicotine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Nicotine results in increased expression of CCN2 protein CTD PMID:22691361 CCN2 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane affects expression ISO Ccn2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19414516 CCN2 Human 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19414516 CCN2 Human 1,2-dimethylhydrazine increases expression ISO Ccn2 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of CCN2 mRNA CTD PMID:22206623 CCN2 Human 1,3-dinitrobenzene increases expression ISO Ccn2 (Rattus norvegicus) 6480464 3-dinitrobenzene results in increased expression of CCN2 mRNA CTD PMID:24140754 CCN2 Human 1,8-cineole multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human 1-naphthyl isothiocyanate increases expression ISO Ccn2 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of CCN2 mRNA CTD PMID:25380136 and PMID:30723492 CCN2 Human 1-nitropyrene increases expression EXP 6480464 1-nitropyrene results in increased expression of CCN2 mRNA CTD PMID:19041380 CCN2 Human 1-octadec-9-enoylglycero-3-phosphate increases expression ISO Ccn2 (Rattus norvegicus) 6480464 lysophosphatidic acid results in increased expression of CCN2 protein CTD PMID:15200425 CCN2 Human 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO Ccn2 (Mus musculus) 6480464 N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 mRNA] CTD PMID:24706986 CCN2 Human 1-octadec-9-enoylglycero-3-phosphate increases expression ISO Ccn2 (Mus musculus) 6480464 lysophosphatidic acid results in increased expression of CCN2 mRNA CTD PMID:24706986 CCN2 Human 1-octadec-9-enoylglycero-3-phosphate multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] and Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 CCN2 Human 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions EXP 6480464 15-deoxy-delta(12 more ... CTD PMID:19429239 CCN2 Human 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of CCN2 mRNA CTD PMID:18936297 CCN2 Human 17alpha-ethynylestradiol affects expression EXP 6480464 Ethinyl Estradiol affects the expression of CCN2 mRNA CTD PMID:20170705 and PMID:26865667 CCN2 Human 17alpha-ethynylestradiol affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Ethinyl Estradiol affects the expression of CCN2 mRNA CTD PMID:20170705 and PMID:26865667 CCN2 Human 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of CCN2 mRNA CTD PMID:14699072 and PMID:25321415 CCN2 Human 17beta-estradiol multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 CCN2 Human 17beta-estradiol increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Estradiol results in increased expression of CTGF mRNA and Estradiol results in increased expression of CTGF protein CTD PMID:32145629 CCN2 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of CCN2 mRNA and Estradiol results in increased expression of CCN2 protein CTD PMID:19153601 more ... CCN2 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA more ... CTD PMID:20823114 more ... CCN2 Human 17beta-estradiol increases expression ISO Ccn2 (Mus musculus) 6480464 Estradiol results in increased expression of CCN2 mRNA CTD PMID:19484750 CCN2 Human 17beta-estradiol 3-benzoate multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 CCN2 Human 2,2',4,4',5,5'-hexachlorobiphenyl increases expression EXP 6480464 2 more ... CTD PMID:38568856 CCN2 Human 2,3,4,7,8-Pentachlorodibenzofuran decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:21724226 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA CTD PMID:19684285 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ccn2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA CTD PMID:15034205 and PMID:26290441 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ccn2 (Mus musculus) 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of CCN2 mRNA CTD PMID:25975270 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:19684285 more ... CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA CTD PMID:23196670 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CCN2 mRNA] CTD PMID:23196670 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:21724226 and PMID:33387578 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ccn2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:20702594 more ... CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:22298810 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of CCN2 mRNA CTD PMID:22298810 and PMID:34747641 CCN2 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ccn2 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of CCN2 mRNA CTD PMID:19770486 and PMID:19933214 CCN2 Human 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO Ccn2 (Mus musculus) 6480464 2 more ... CTD PMID:20702594 CCN2 Human 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:21724226 CCN2 Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Ccn2 (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA CTD PMID:25740948 CCN2 Human 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 CCN2 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Ccn2 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 CCN2 Human 2-acetamidofluorene increases expression ISO Ccn2 (Rattus norvegicus) 6480464 2-Acetylaminofluorene results in increased expression of CCN2 mRNA and 2-Acetylaminofluorene results in increased expression of CCN2 protein CTD PMID:15940639 CCN2 Human 2-acetamidofluorene multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA] CTD PMID:15940639 CCN2 Human 2-amino-2-deoxy-D-glucopyranose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 CCN2 Human 2-butoxyethanol increases expression ISO Ccn2 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of CCN2 mRNA CTD PMID:19812364 CCN2 Human 2-methoxyethanol increases expression ISO Ccn2 (Rattus norvegicus) 6480464 methyl cellosolve results in increased expression of CCN2 mRNA CTD PMID:21061450 CCN2 Human 2-tert-butylhydroquinone decreases expression ISO Ccn2 (Mus musculus) 6480464 2-tert-butylhydroquinone results in decreased expression of CCN2 mRNA CTD PMID:16014739 CCN2 Human 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] CTD PMID:15298857 CCN2 Human 3',5'-cyclic AMP multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 2 more ... CTD PMID:19414516 CCN2 Human 3,3',4,4',5-pentachlorobiphenyl affects expression ISO Ccn2 (Mus musculus) 6480464 3 more ... CTD PMID:20702594 CCN2 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Ccn2 (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 and PMID:32119087 CCN2 Human 3,4-dichloroaniline decreases expression EXP 6480464 3 and 4-dichloroaniline results in decreased expression of CCN2 mRNA CTD PMID:24172598 CCN2 Human 3,4-methylenedioxymethamphetamine decreases expression ISO Ccn2 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of CCN2 mRNA CTD PMID:20188158 CCN2 Human 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:10026205 CCN2 Human 3-phenylprop-2-enal decreases expression EXP 6480464 cinnamaldehyde results in decreased expression of CCN2 mRNA CTD PMID:17178418 CCN2 Human 4'-epidoxorubicin increases expression ISO Ccn2 (Mus musculus) 6480464 Epirubicin results in increased expression of CCN2 mRNA CTD PMID:22712078 CCN2 Human 4'-epidoxorubicin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Lovastatin inhibits the reaction [Epirubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 CCN2 Human 4,4'-diaminodiphenylmethane increases expression ISO Ccn2 (Rattus norvegicus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of CCN2 mRNA CTD PMID:25380136 CCN2 Human 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of CCN2 mRNA CTD PMID:25912373 CCN2 Human 4,4'-sulfonyldiphenol affects methylation ISO Ccn2 (Mus musculus) 6480464 bisphenol S affects the methylation of CTGF gene CTD PMID:31683443 CCN2 Human 4,4'-sulfonyldiphenol increases methylation EXP 6480464 bisphenol S results in increased methylation of CCN2 gene CTD PMID:31601247 CCN2 Human 4,4'-sulfonyldiphenol increases expression ISO Ccn2 (Mus musculus) 6480464 bisphenol S results in increased expression of CCN2 mRNA CTD PMID:30951980 and PMID:37611474 CCN2 Human 4,4'-sulfonyldiphenol multiple interactions ISO Ccn2 (Mus musculus) 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 CCN2 Human 4-hydroxy-TEMPO decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 tempol results in decreased expression of CCN2 mRNA CTD PMID:16685210 CCN2 Human 4-hydroxyphenyl retinamide increases expression ISO Ccn2 (Mus musculus) 6480464 Fenretinide results in increased expression of CCN2 mRNA CTD PMID:28973697 CCN2 Human 5-aza-2'-deoxycytidine affects expression EXP 6480464 Decitabine affects the expression of CCN2 mRNA CTD PMID:23300844 CCN2 Human 5-aza-2'-deoxycytidine decreases expression ISO Ccn2 (Mus musculus) 6480464 Decitabine results in decreased expression of CCN2 mRNA CTD PMID:27915011 CCN2 Human 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of CCN2 mRNA CTD PMID:21856257 CCN2 Human 5-fluorouracil affects expression EXP 6480464 Fluorouracil affects the expression of CCN2 mRNA CTD PMID:15205334 CCN2 Human 6-propyl-2-thiouracil decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of CCN2 mRNA CTD PMID:24780913 and PMID:25825206 CCN2 Human 6-propyl-2-thiouracil multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CCN2 mRNA CTD PMID:36706583 CCN2 Human 6alpha-methylprednisolone increases expression EXP 6480464 Methylprednisolone results in increased expression of CCN2 mRNA CTD PMID:19192274 CCN2 Human 7,12-dimethyltetraphene increases expression ISO Ccn2 (Rattus norvegicus) 6480464 9 more ... CTD PMID:19480007 CCN2 Human 7,12-dimethyltetraphene increases expression ISO Ccn2 (Mus musculus) 6480464 9 more ... CTD PMID:32553695 CCN2 Human acetaldehyde increases abundance ISO Ccn2 (Mus musculus) 6480464 CCN2 protein results in increased abundance of Acetaldehyde CTD PMID:19280452 CCN2 Human acetaldehyde increases expression ISO Ccn2 (Mus musculus) 6480464 Acetaldehyde results in increased expression of CCN2 mRNA CTD PMID:19280452 CCN2 Human acetaldehyde multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Ethanol results in increased expression of CCN2 protein] which results in increased abundance of Acetaldehyde CTD PMID:19280452 CCN2 Human acetamide increases expression ISO Ccn2 (Rattus norvegicus) 6480464 acetamide results in increased expression of CCN2 mRNA CTD PMID:31881176 CCN2 Human acetylsalicylic acid multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] and Aspirin inhibits the reaction [Streptozocin results in increased expression of CCN2 mRNA] CTD PMID:14586741 CCN2 Human acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of CCN2 mRNA CTD PMID:32763439 CCN2 Human adenine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Adenine results in increased expression of CCN2 mRNA CTD PMID:25766432 CCN2 Human adenine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 camostat inhibits the reaction [Adenine results in increased expression of CCN2 mRNA] CTD PMID:25766432 CCN2 Human afimoxifene multiple interactions EXP 6480464 GPER1 protein affects the reaction [afimoxifene results in increased expression of CCN2 mRNA] CTD PMID:19153601 CCN2 Human afimoxifene increases expression EXP 6480464 afimoxifene results in increased expression of CCN2 mRNA and afimoxifene results in increased expression of CCN2 protein CTD PMID:19153601 CCN2 Human afimoxifene affects response to substance EXP 6480464 CCN2 protein affects the susceptibility to afimoxifene CTD PMID:19153601 CCN2 Human aflatoxin B1 decreases expression ISO Ccn2 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of CCN2 mRNA CTD PMID:19770486 CCN2 Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of CCN2 mRNA CTD PMID:32234424 CCN2 Human aflatoxin B1 increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of CCN2 mRNA CTD PMID:33354967 CCN2 Human aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of CCN2 mRNA CTD PMID:27153756 CCN2 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of CCN2 gene CTD PMID:27153756 CCN2 Human aflatoxin M1 decreases expression EXP 6480464 Aflatoxin M1 results in decreased expression of CCN2 mRNA CTD PMID:30928695 CCN2 Human aldehydo-D-glucosamine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 CCN2 Human aldehydo-D-glucose multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... CCN2 Human aldehydo-D-glucose multiple interactions ISO Ccn2 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 CCN2 Human aldehydo-D-glucose increases expression ISO Ccn2 (Mus musculus) 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 CCN2 Human aldehydo-D-glucose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... CCN2 Human aldehydo-D-glucose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... CCN2 Human aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... CCN2 Human aldosterone increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Aldosterone results in increased expression of CCN2 protein CTD PMID:17278980 CCN2 Human aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of CCN2 mRNA CTD PMID:30809271 CCN2 Human aldosterone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of CCN2 protein] CTD PMID:17278980 CCN2 Human all-trans-retinoic acid multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 mRNA] and Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 protein] CTD PMID:21258935 CCN2 Human all-trans-retinoic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of CCN2 mRNA more ... CTD PMID:30951980 CCN2 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of CCN2 mRNA CTD PMID:23830798 CCN2 Human all-trans-retinoic acid increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Tretinoin results in increased expression of CCN2 mRNA and Tretinoin results in increased expression of CCN2 protein CTD PMID:20488242 and PMID:21258935 CCN2 Human alpha-D-galactose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Galactose results in increased expression of CCN2 protein CTD PMID:30367734 CCN2 Human alpha-D-galactose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of CCN2 protein] CTD PMID:30367734 CCN2 Human amiodarone increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Amiodarone results in increased expression of CCN2 mRNA CTD PMID:32909452 CCN2 Human ammonium chloride affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of CCN2 mRNA CTD PMID:16483693 CCN2 Human Ammothamnine multiple interactions ISO Ccn2 (Mus musculus) 6480464 oxymatrine inhibits the reaction [SNHG6 results in increased expression of CCN2 protein] CTD PMID:35785413 CCN2 Human andrographolide multiple interactions ISO Ccn2 (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA CTD PMID:19737545 CCN2 Human anthocyanin decreases expression ISO Ccn2 (Mus musculus) 6480464 Anthocyanins results in decreased expression of CCN2 mRNA CTD PMID:30056145 CCN2 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 [pyrazolanthrone co-treated with U 0126] inhibits the reaction [fisetin results in decreased expression of CCN2 protein] more ... CTD PMID:31044527 CCN2 Human antimycin A increases expression EXP 6480464 Antimycin A results in increased expression of CCN2 mRNA CTD PMID:33512557 CCN2 Human antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of CCN2 mRNA CTD PMID:24449571 CCN2 Human aristolochic acid A multiple interactions ISO Ccn2 (Mus musculus) 6480464 aristolochic acid I inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in decreased expression of CCN2 protein] CTD PMID:24412304 CCN2 Human aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of CCN2 mRNA and aristolochic acid I results in decreased expression of CCN2 protein CTD PMID:33212167 CCN2 Human aristolochic acids increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Aristolochic Acids results in increased expression of CCN2 mRNA CTD PMID:19717638 CCN2 Human arsane affects expression EXP 6480464 Arsenic affects the expression of CCN2 protein CTD PMID:24675094 CCN2 Human arsane multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 CCN2 Human arsane increases expression ISO Ccn2 (Mus musculus) 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:23942117 CCN2 Human arsane multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of CCN2 mRNA] CTD PMID:24348802 CCN2 Human arsane increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:24348802 CCN2 Human arsenic atom increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:24348802 CCN2 Human arsenic atom multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 CCN2 Human arsenic atom increases expression ISO Ccn2 (Mus musculus) 6480464 Arsenic results in increased expression of CCN2 mRNA CTD PMID:23942117 CCN2 Human arsenic atom affects expression EXP 6480464 Arsenic affects the expression of CCN2 protein CTD PMID:24675094 CCN2 Human arsenic atom multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Grape Seed Extract inhibits the reaction [Arsenic results in increased expression of CCN2 mRNA] CTD PMID:24348802 CCN2 Human arsenite(3-) multiple interactions EXP 6480464 arsenite inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA] CTD PMID:31646340 CCN2 Human arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of CCN2 mRNA CTD PMID:31646340 CCN2 Human arsenous acid multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA] CTD PMID:24762191 CCN2 Human asbestos decreases expression EXP 6480464 Asbestos results in decreased expression of CCN2 mRNA CTD PMID:22076105 CCN2 Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of CCN2 mRNA and Atrazine results in increased expression of CCN2 protein CTD PMID:25616260 CCN2 Human atrazine multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Atrazine results in increased expression of CCN2 protein] and GPER1 protein promotes the reaction [Atrazine results in increased expression of CCN2 protein] CTD PMID:25616260 CCN2 Human bazedoxifene increases expression EXP 6480464 bazedoxifene results in increased expression of CCN2 mRNA CTD PMID:19914376 CCN2 Human belinostat increases expression EXP 6480464 belinostat results in increased expression of CCN2 mRNA CTD PMID:19606018 and PMID:23671600 CCN2 Human benazepril decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 benazepril results in decreased expression of CCN2 mRNA CTD PMID:17121042 CCN2 Human benzalkonium chloride decreases expression EXP 6480464 Benzalkonium Compounds results in decreased expression of CCN2 mRNA CTD PMID:25377654 CCN2 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of CCN2 mRNA CTD PMID:20106945 and PMID:21632981 CCN2 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of CCN2 3' UTR CTD PMID:27901495 CCN2 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of CCN2 mRNA CTD PMID:35870112 CCN2 Human benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of CCN2 promoter CTD PMID:27901495 CCN2 Human benzo[a]pyrene decreases expression ISO Ccn2 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of CCN2 mRNA CTD PMID:15034205 and PMID:19770486 CCN2 Human benzo[a]pyrene multiple interactions ISO Ccn2 (Mus musculus) 6480464 AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of CCN2 mRNA] CTD PMID:15034205 CCN2 Human benzo[a]pyrene increases expression ISO Ccn2 (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of CCN2 mRNA and Benzo(a)pyrene results in increased expression of CCN2 mRNA CTD PMID:21569818 more ... CCN2 Human benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:20018196 CCN2 Human beta-D-glucosamine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucosamine analog results in increased expression of CCN2 mRNA CTD PMID:21466783 CCN2 Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of CTGF mRNA CTD PMID:38218311 CCN2 Human beta-naphthoflavone multiple interactions ISO Ccn2 (Mus musculus) 6480464 [andrographolide co-treated with beta-Naphthoflavone] results in decreased expression of CCN2 mRNA CTD PMID:19737545 CCN2 Human beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of CCN2 mRNA CTD PMID:19737606 and PMID:32151702 CCN2 Human beta-naphthoflavone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA CTD PMID:18164116 CCN2 Human Betanin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 CCN2 Human bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:19429239 CCN2 Human bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of CCN2 mRNA CTD PMID:16173061 and PMID:25102026 CCN2 Human bis(2-ethylhexyl) phthalate increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of CCN2 protein CTD PMID:29669060 CCN2 Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of CCN2 mRNA CTD PMID:20170705 and PMID:30903817 CCN2 Human bisphenol A increases expression ISO Ccn2 (Mus musculus) 6480464 bisphenol A results in increased expression of CCN2 mRNA CTD PMID:30951980 and PMID:33912069 CCN2 Human bisphenol A decreases expression ISO Ccn2 (Mus musculus) 6480464 bisphenol A results in decreased expression of CCN2 mRNA CTD PMID:37105096 CCN2 Human bisphenol A increases expression ISO Ccn2 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of CCN2 mRNA and bisphenol A results in increased expression of CTGF protein CTD PMID:32145629 CCN2 Human bisphenol A multiple interactions ISO Ccn2 (Mus musculus) 6480464 [bisphenol A co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 CCN2 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CCN2 mRNA CTD PMID:27685785 more ... CCN2 Human bisphenol A decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of CCN2 mRNA and bisphenol A results in decreased expression of CCN2 protein CTD PMID:24552547 and PMID:34947998 CCN2 Human bisphenol A affects expression ISO Ccn2 (Rattus norvegicus) 6480464 bisphenol A affects the expression of CCN2 mRNA CTD PMID:25181051 CCN2 Human bisphenol A multiple interactions EXP 6480464 bisphenol A promotes the reaction [CCN2 protein binds to ESR1 protein] and GPER1 mRNA affects the reaction [bisphenol A results in increased expression of CCN2 protein] CTD PMID:22552965 and PMID:27156127 CCN2 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CCN2 mRNA and bisphenol A results in increased expression of CCN2 protein CTD PMID:22552965 CCN2 Human bisphenol F multiple interactions ISO Ccn2 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of CCN2 mRNA CTD PMID:30951980 CCN2 Human bisphenol F increases expression ISO Ccn2 (Mus musculus) 6480464 bisphenol F results in increased expression of CCN2 mRNA CTD PMID:30951980 CCN2 Human bleomycin A2 increases expression ISO Ccn2 (Mus musculus) 6480464 Bleomycin results in increased expression of CCN2 mRNA and Bleomycin results in increased expression of CCN2 protein CTD PMID:19080365 more ... CCN2 Human bleomycin A2 multiple interactions ISO Ccn2 (Mus musculus) 6480464 [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA] more ... CTD PMID:19080365 more ... CCN2 Human bromobenzene increases expression ISO Ccn2 (Rattus norvegicus) 6480464 bromobenzene results in increased expression of CCN2 mRNA CTD PMID:32479839 CCN2 Human bucladesine multiple interactions EXP 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 CCN2 Human buta-1,3-diene increases expression ISO Ccn2 (Mus musculus) 6480464 1 and 3-butadiene results in increased expression of CCN2 mRNA CTD PMID:29038090 CCN2 Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCN2 mRNA more ... CTD PMID:19369054 more ... CCN2 Human cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of CCN2 mRNA CTD PMID:31646340 CCN2 Human cadmium atom multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Dietary Fats] results in increased expression of CCN2 mRNA and [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA CTD PMID:30912652 and PMID:31904401 CCN2 Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CCN2 mRNA CTD PMID:36602393 CCN2 Human cadmium dichloride increases expression ISO Ccn2 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of CCN2 mRNA CTD PMID:35027733 CCN2 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of CCN2 mRNA CTD PMID:26314618 CCN2 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of CCN2 mRNA and Cadmium Chloride results in increased expression of CTGF mRNA CTD PMID:26472689 more ... CCN2 Human cadmium dichloride increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of CCN2 mRNA CTD PMID:33453195 CCN2 Human cadmium dichloride multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Dietary Fats] results in increased expression of CCN2 mRNA more ... CTD PMID:20371981 more ... CCN2 Human cadmium dichloride affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Cadmium Chloride affects the expression of CCN2 mRNA CTD PMID:22110744 CCN2 Human calciol decreases expression ISO Ccn2 (Mus musculus) 6480464 Cholecalciferol results in decreased expression of CCN2 mRNA CTD PMID:16508948 CCN2 Human calciol increases expression ISO Ccn2 (Mus musculus) 6480464 Cholecalciferol results in increased expression of CCN2 mRNA CTD PMID:17170073 CCN2 Human camostat multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 camostat inhibits the reaction [Adenine results in increased expression of CCN2 mRNA] and camostat inhibits the reaction [PLG protein modified form results in increased expression of CCN2 mRNA] CTD PMID:25766432 and PMID:27773435 CCN2 Human camphor multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human candesartan decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 candesartan results in decreased expression of CCN2 mRNA CTD PMID:16685210 CCN2 Human Candesartan cilexetil multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CCN2 protein] CTD PMID:27889505 CCN2 Human cannabidiol increases expression EXP 6480464 Cannabidiol results in increased expression of CCN2 mRNA CTD PMID:33244087 CCN2 Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of CCN2 mRNA CTD PMID:25979313 CCN2 Human carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of CCN2 mRNA CTD PMID:22076105 CCN2 Human carbon nanotube decreases expression ISO Ccn2 (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of CCN2 mRNA CTD PMID:25554681 CCN2 Human carbon nanotube increases expression ISO Ccn2 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 CCN2 Human carbonyl sulfide increases expression ISO Ccn2 (Rattus norvegicus) 6480464 carbonyl sulfide results in increased expression of CCN2 mRNA CTD PMID:19395590 CCN2 Human cefaloridine decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Cephaloridine results in decreased expression of CCN2 mRNA CTD PMID:18500788 CCN2 Human CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to CCN2 gene] CTD PMID:28238834 CCN2 Human chlordecone decreases expression ISO Ccn2 (Mus musculus) 6480464 Chlordecone results in decreased expression of CCN2 mRNA CTD PMID:33711761 CCN2 Human chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of CCN2 mRNA CTD PMID:26352163 CCN2 Human chloroprene increases expression ISO Ccn2 (Mus musculus) 6480464 Chloroprene results in increased expression of CCN2 mRNA CTD PMID:23125180 CCN2 Human chlorpromazine decreases expression EXP 6480464 Chlorpromazine results in decreased expression of CCN2 mRNA and Chlorpromazine results in decreased expression of CCN2 protein CTD PMID:30703373 CCN2 Human choline multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA more ... CTD PMID:18991162 more ... CCN2 Human chromium(6+) multiple interactions EXP 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of CCN2 mRNA CTD PMID:38479592 CCN2 Human cisplatin increases expression ISO Ccn2 (Mus musculus) 6480464 Cisplatin results in increased expression of CCN2 mRNA CTD PMID:21151649 CCN2 Human cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of CCN2 mRNA CTD PMID:27392435 CCN2 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of CCN2 mRNA and Cisplatin results in increased expression of CTGF mRNA CTD PMID:33545341 and PMID:38498338 CCN2 Human cisplatin affects expression EXP 6480464 Cisplatin affects the expression of CCN2 mRNA CTD PMID:23300844 CCN2 Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of CCN2 mRNA and [Cisplatin co-treated with Paclitaxel] affects the expression of CCN2 mRNA CTD PMID:20705681 and PMID:27392435 CCN2 Human clobetasol increases expression ISO Ccn2 (Mus musculus) 6480464 Clobetasol results in increased expression of CCN2 mRNA CTD PMID:27462272 CCN2 Human cobalt atom decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Cobalt results in decreased expression of CCN2 mRNA CTD PMID:17967803 CCN2 Human cobalt dichloride multiple interactions EXP 6480464 cobaltous chloride promotes the reaction [HIF1A protein results in increased expression of CCN2 mRNA] more ... CTD PMID:17034590 CCN2 Human cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of CCN2 mRNA CTD PMID:19320972 CCN2 Human cobalt dichloride decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 cobaltous chloride results in decreased expression of CCN2 mRNA CTD PMID:24386269 CCN2 Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of CCN2 mRNA CTD PMID:17034590 and PMID:19376846 CCN2 Human cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of CCN2 mRNA and Cocaine results in decreased expression of CCN2 protein CTD PMID:18000554 CCN2 Human coenzyme Q10 multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CCN2 protein] CTD PMID:27087047 CCN2 Human copper atom multiple interactions EXP 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN2 mRNA CTD PMID:20971185 CCN2 Human copper atom increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Copper results in increased expression of CCN2 mRNA CTD PMID:30556269 CCN2 Human copper(0) multiple interactions EXP 6480464 [NSC 689534 binds to Copper] which results in increased expression of CCN2 mRNA CTD PMID:20971185 CCN2 Human copper(0) increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Copper results in increased expression of CCN2 mRNA CTD PMID:30556269 CCN2 Human copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human copper(II) sulfate affects expression EXP 6480464 Copper Sulfate affects the expression of CCN2 mRNA CTD PMID:19549813 CCN2 Human crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of CCN2 mRNA CTD PMID:18687144 CCN2 Human curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of CCN2 mRNA and Curcumin results in decreased expression of CCN2 protein CTD PMID:17965732 and PMID:19764552 CCN2 Human curcumin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Curcumin results in decreased expression of CCN2 protein CTD PMID:17965732 CCN2 Human curcumin multiple interactions EXP 6480464 IKBKB protein inhibits the reaction [Curcumin results in decreased expression of CCN2 mRNA] more ... CTD PMID:17965732 CCN2 Human cycloheximide increases expression EXP 6480464 Cycloheximide results in increased expression of CCN2 mRNA CTD PMID:19684285 CCN2 Human cycloheximide multiple interactions EXP 6480464 [Tetrachlorodibenzodioxin co-treated with Cycloheximide] results in decreased expression of CCN2 mRNA CTD PMID:19684285 CCN2 Human cyclophosphamide decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Cyclophosphamide results in decreased expression of CCN2 mRNA and Cyclophosphamide results in decreased expression of CCN2 protein CTD PMID:36154502 CCN2 Human cyclophosphamide multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 mRNA] and Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 protein] CTD PMID:36154502 CCN2 Human cyclosporin A affects expression EXP 6480464 Cyclosporine affects the expression of CCN2 mRNA CTD PMID:20106945 CCN2 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CCN2 mRNA and Cyclosporine results in decreased expression of CTGF mRNA CTD PMID:25562108 more ... CCN2 Human cyclosporin A affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Cyclosporine affects the expression of CCN2 mRNA and Cyclosporine affects the expression of CCN2 protein CTD PMID:24971338 CCN2 Human cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of CCN2 mRNA CTD PMID:27344345 CCN2 Human cyclosporin A multiple interactions ISO Ccn2 (Mus musculus) 6480464 Cyclosporine results in increased expression of and results in increased secretion of CCN2 protein CTD PMID:21354196 CCN2 Human cyclosporin A increases expression ISO Ccn2 (Mus musculus) 6480464 Cyclosporine results in increased expression of CCN2 mRNA CTD PMID:21354196 CCN2 Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of CCN2 mRNA CTD PMID:21632981 CCN2 Human cyclosporin A decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Cyclosporine results in decreased expression of CCN2 mRNA CTD PMID:21865292 CCN2 Human D-glucose multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... CCN2 Human D-glucose multiple interactions ISO Ccn2 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 CCN2 Human D-glucose increases expression ISO Ccn2 (Mus musculus) 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 CCN2 Human D-glucose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... CCN2 Human D-glucose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... CCN2 Human D-glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... CCN2 Human DDT decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 DDT results in decreased expression of CCN2 mRNA CTD PMID:30207508 CCN2 Human deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of CCN2 mRNA CTD PMID:35588983 CCN2 Human dexamethasone increases expression ISO Ccn2 (Mus musculus) 6480464 Dexamethasone results in increased expression of CCN2 mRNA CTD PMID:22733784 CCN2 Human Diallyl sulfide multiple interactions ISO Ccn2 (Mus musculus) 6480464 allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA] and allyl sulfide inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 CCN2 Human diarsenic trioxide multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA] CTD PMID:24762191 CCN2 Human dibenz[a,h]anthracene increases expression ISO Ccn2 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 CCN2 Human dibenzo[a,l]pyrene increases expression EXP 6480464 dibenzo(a and l)pyrene results in increased expression of CCN2 mRNA CTD PMID:15735009 CCN2 Human dibutyl phthalate increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of CCN2 mRNA CTD PMID:21266533 CCN2 Human dibutyl phthalate increases expression ISO Ccn2 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of CCN2 mRNA CTD PMID:17361019 and PMID:21266533 CCN2 Human dichloroacetic acid decreases expression ISO Ccn2 (Mus musculus) 6480464 Dichloroacetic Acid results in decreased expression of CCN2 mRNA CTD PMID:28962523 CCN2 Human dichloroacetic acid decreases expression EXP 6480464 Dichloroacetic Acid results in decreased expression of CCN2 mRNA CTD PMID:33405312 CCN2 Human dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of CCN2 mRNA CTD PMID:28302478 CCN2 Human diethyl malate increases expression EXP 6480464 diethyl malate results in increased expression of CTGF mRNA CTD PMID:38498338 CCN2 Human diiodine multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Propylthiouracil co-treated with Iodine deficiency] results in decreased expression of CCN2 mRNA CTD PMID:36706583 CCN2 Human dioxygen affects expression ISO Ccn2 (Mus musculus) 6480464 Oxygen deficiency affects the expression of CCN2 mRNA CTD PMID:17193925 CCN2 Human dioxygen multiple interactions ISO Ccn2 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CCN2 mRNA more ... CTD PMID:30096613 and PMID:30529165 CCN2 Human dioxygen increases expression ISO Ccn2 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of CCN2 protein CTD PMID:24657099 and PMID:30096613 CCN2 Human dioxygen increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Oxygen results in increased expression of CCN2 mRNA CTD PMID:22911455 CCN2 Human dioxygen multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of CCN2 mRNA and CCN2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] CTD PMID:21124846 and PMID:33729688 CCN2 Human diquat decreases expression ISO Ccn2 (Mus musculus) 6480464 Diquat results in decreased expression of CCN2 mRNA CTD PMID:36851058 CCN2 Human diuron increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Diuron results in increased expression of CCN2 mRNA CTD PMID:21551480 CCN2 Human diuron decreases expression EXP 6480464 Diuron metabolite results in decreased expression of CCN2 mRNA CTD PMID:24172598 CCN2 Human divanadium pentaoxide decreases expression EXP 6480464 vanadium pentoxide results in decreased expression of CCN2 mRNA CTD PMID:17459161 CCN2 Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 CCN2 Human doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of CCN2 mRNA CTD PMID:15205334 CCN2 Human doxorubicin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Doxorubicin results in decreased expression of CTGF mRNA CTD PMID:37597758 CCN2 Human doxorubicin increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of CCN2 mRNA and Doxorubicin results in increased expression of CCN2 protein CTD PMID:27087047 and PMID:31307187 CCN2 Human doxorubicin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 coenzyme Q10 inhibits the reaction [Doxorubicin results in increased expression of CCN2 protein] more ... CTD PMID:27087047 more ... CCN2 Human doxorubicin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] and NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 and PMID:28710503 CCN2 Human doxorubicin increases expression ISO Ccn2 (Mus musculus) 6480464 Doxorubicin results in increased expression of CCN2 mRNA and Doxorubicin results in increased expression of CCN2 protein CTD PMID:22712078 more ... CCN2 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of CCN2 mRNA CTD PMID:16579640 more ... CCN2 Human doxorubicin affects expression ISO Ccn2 (Mus musculus) 6480464 Doxorubicin affects the expression of CCN2 mRNA CTD PMID:15033991 and PMID:36227756 CCN2 Human EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 7-Ala-angiotensin (1-7) inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [AGT protein results in increased expression of CCN2 protein]] and Angiotensin-Converting Enzyme Inhibitors inhibits the reaction [AGT protein results in increased expression of CCN2 protein] CTD PMID:19793108 CCN2 Human enalapril decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Enalapril results in decreased expression of CCN2 mRNA and Enalapril results in decreased expression of CCN2 protein CTD PMID:18812665 and PMID:19349682 CCN2 Human enalapril multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Enalapril inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:21416479 CCN2 Human enalapril decreases expression ISO Ccn2 (Mus musculus) 6480464 Enalapril results in decreased expression of CCN2 mRNA CTD PMID:25037058 CCN2 Human endosulfan affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Endosulfan affects the expression of CCN2 mRNA CTD PMID:29391264 CCN2 Human erythromycin estolate decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Erythromycin Estolate results in decreased expression of CCN2 mRNA CTD PMID:24412560 CCN2 Human ethanol multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA more ... CTD PMID:19280452 and PMID:21863215 CCN2 Human ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of CCN2 mRNA CTD PMID:31059573 CCN2 Human ethanol multiple interactions EXP 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CCN2 mRNA CTD PMID:29432896 CCN2 Human ethanol increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Ethanol results in increased expression of CCN2 mRNA CTD PMID:16098508 CCN2 Human ethanol increases expression ISO Ccn2 (Mus musculus) 6480464 Ethanol results in increased expression of CCN2 protein CTD PMID:19280452 and PMID:28962519 CCN2 Human etoposide increases expression EXP 6480464 Etoposide results in increased expression of CCN2 mRNA CTD PMID:29397400 CCN2 Human fenofibrate increases expression ISO Ccn2 (Mus musculus) 6480464 Fenofibrate results in increased expression of CCN2 protein CTD PMID:39442682 CCN2 Human ferulic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of CTGF protein] CTD PMID:33428986 CCN2 Human fipronil increases expression ISO Ccn2 (Rattus norvegicus) 6480464 fipronil results in increased expression of CCN2 mRNA CTD PMID:34044035 CCN2 Human fisetin decreases expression EXP 6480464 fisetin results in decreased expression of CCN2 protein CTD PMID:31044527 CCN2 Human fisetin multiple interactions EXP 6480464 [pyrazolanthrone co-treated with U 0126] inhibits the reaction [fisetin results in decreased expression of CCN2 protein] more ... CTD PMID:31044527 CCN2 Human folic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CCN2 more ... CTD PMID:20938992 CCN2 Human folic acid decreases expression ISO Ccn2 (Mus musculus) 6480464 Folic Acid results in decreased expression of CCN2 mRNA CTD PMID:25629700 CCN2 Human fomepizole multiple interactions ISO Ccn2 (Mus musculus) 6480464 Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA] and Fomepizole inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 CCN2 Human fonofos increases methylation EXP 6480464 Fonofos results in increased methylation of CCN2 promoter CTD PMID:22847954 CCN2 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of CCN2 mRNA CTD PMID:20655997 more ... CCN2 Human fructose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 betanin inhibits the reaction [Fructose results in increased expression of CCN2 protein] CTD PMID:25559852 CCN2 Human fructose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Fructose results in increased expression of CCN2 protein CTD PMID:25559852 CCN2 Human fulvestrant increases expression EXP 6480464 Fulvestrant results in increased expression of CCN2 mRNA CTD PMID:31646340 CCN2 Human fulvestrant multiple interactions EXP 6480464 arsenite inhibits the reaction [Fulvestrant results in increased expression of CCN2 mRNA] more ... CTD PMID:31646340 CCN2 Human furan increases expression ISO Ccn2 (Rattus norvegicus) 6480464 furan results in increased expression of CCN2 mRNA more ... CTD PMID:27371368 more ... CCN2 Human galactose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Alpinia oxyphylla fruit extract inhibits the reaction [Galactose results in increased expression of CCN2 protein] CTD PMID:30367734 CCN2 Human galactose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Galactose results in increased expression of CCN2 protein CTD PMID:30367734 CCN2 Human genistein decreases expression EXP 6480464 Genistein results in decreased expression of CCN2 mRNA CTD PMID:20884965 CCN2 Human genistein affects expression EXP 6480464 Genistein affects the expression of CCN2 mRNA CTD PMID:26865667 CCN2 Human gentamycin increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of CCN2 mRNA CTD PMID:33387578 CCN2 Human glucose multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of CCN2 protein] more ... CTD PMID:10026205 more ... CCN2 Human glucose multiple interactions ISO Ccn2 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]] and SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] CTD PMID:33270355 CCN2 Human glucose increases expression ISO Ccn2 (Mus musculus) 6480464 Glucose results in increased expression of CCN2 mRNA CTD PMID:33270355 CCN2 Human glucose increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:14586741 more ... CCN2 Human glucose multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Aspirin inhibits the reaction [Glucose results in increased expression of CCN2 mRNA] more ... CTD PMID:14586741 more ... CCN2 Human glucose increases expression EXP 6480464 Glucose results in increased expression of CCN2 mRNA and Glucose results in increased expression of CCN2 protein CTD PMID:10026205 more ... CCN2 Human gypenoside LXXV increases expression ISO Ccn2 (Mus musculus) 6480464 gypenoside LXXV results in increased expression of CTGF mRNA CTD PMID:31018484 CCN2 Human gypenoside LXXV multiple interactions ISO Ccn2 (Mus musculus) 6480464 gypenoside LXXV results in increased expression of and results in increased secretion of CTGF protein CTD PMID:31018484 CCN2 Human hexadecanoic acid increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Palmitic Acid results in increased expression of CCN2 protein CTD PMID:34310909 CCN2 Human hexadecanoic acid multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 CXCL12 protein inhibits the reaction [Palmitic Acid results in increased expression of CCN2 protein] more ... CTD PMID:34310909 CCN2 Human Honokiol multiple interactions ISO Ccn2 (Mus musculus) 6480464 honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:32032644 CCN2 Human Honokiol affects expression ISO Ccn2 (Rattus norvegicus) 6480464 honokiol affects the expression of CCN2 mRNA CTD PMID:21265825 CCN2 Human Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 mRNA] and honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:21265825 and PMID:32032644 CCN2 Human Honokiol multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:21265825 CCN2 Human hydrogen cyanide increases expression ISO Ccn2 (Mus musculus) 6480464 Hydrogen Cyanide results in increased expression of CCN2 mRNA CTD PMID:33914522 CCN2 Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of CCN2 mRNA and Hydrogen Peroxide results in increased expression of CCN2 protein CTD PMID:15147944 and PMID:32949572 CCN2 Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of CCN2 mRNA CTD PMID:20044591 and PMID:23410634 CCN2 Human hydrogen sulfide increases expression ISO Ccn2 (Mus musculus) 6480464 Hydrogen Sulfide results in increased expression of CCN2 mRNA CTD PMID:31843631 CCN2 Human hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of CCN2 mRNA CTD PMID:31256213 CCN2 Human idebenone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 idebenone inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:28648635 and PMID:34175429 CCN2 Human iloprost multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Iloprost inhibits the reaction [2-Acetylaminofluorene results in increased expression of CCN2 mRNA] CTD PMID:15940639 CCN2 Human indole-3-methanol affects expression ISO Ccn2 (Rattus norvegicus) 6480464 indole-3-carbinol affects the expression of CCN2 mRNA CTD PMID:21396975 CCN2 Human indometacin increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Indomethacin results in increased expression of CCN2 mRNA CTD PMID:12077510 CCN2 Human irinotecan increases expression EXP 6480464 Irinotecan results in increased expression of CCN2 mRNA CTD PMID:20185912 CCN2 Human isobutanol multiple interactions EXP 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of CCN2 mRNA CTD PMID:29432896 CCN2 Human isoprenaline increases expression ISO Ccn2 (Mus musculus) 6480464 Isoproterenol results in increased expression of CCN2 mRNA CTD PMID:20003209 CCN2 Human isoprenaline multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA] more ... CTD PMID:24117263 CCN2 Human isoprenaline increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of CCN2 mRNA and Isoproterenol results in increased expression of CCN2 protein CTD PMID:24117263 CCN2 Human isoprenaline decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Isoproterenol results in decreased expression of CCN2 mRNA CTD PMID:24286936 CCN2 Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of CCN2 mRNA and Ivermectin results in decreased expression of CCN2 protein CTD PMID:33955514 CCN2 Human ivermectin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Ivermectin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:36555680 CCN2 Human jaspamide multiple interactions EXP 6480464 jasplakinolide results in increased expression of and results in increased secretion of CCN2 protein and YAP1 protein affects the reaction [jasplakinolide results in increased expression of CCN2 protein] CTD PMID:24040060 CCN2 Human jaspamide increases expression EXP 6480464 jasplakinolide results in increased expression of CCN2 mRNA CTD PMID:24040060 and PMID:25690654 CCN2 Human jaspamide increases expression ISO Ccn2 (Mus musculus) 6480464 jasplakinolide results in increased expression of CCN2 mRNA CTD PMID:25690654 CCN2 Human L-ascorbic acid 2-phosphate decreases expression EXP 6480464 ascorbate-2-phosphate results in decreased expression of CCN2 mRNA CTD PMID:17306970 CCN2 Human L-methionine multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA more ... CTD PMID:18991162 more ... CCN2 Human lead diacetate decreases expression ISO Ccn2 (Mus musculus) 6480464 lead acetate results in decreased expression of CCN2 mRNA CTD PMID:25270620 CCN2 Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human leflunomide increases expression EXP 6480464 Leflunomide results in increased expression of CCN2 mRNA CTD PMID:28988120 CCN2 Human letrozole increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Letrozole results in increased expression of CCN2 protein CTD PMID:33491863 CCN2 Human letrozole multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 ADM protein inhibits the reaction [Letrozole results in increased expression of CCN2 protein] CTD PMID:33491863 CCN2 Human Licochalcone A decreases expression EXP 6480464 licochalcone A results in decreased expression of CCN2 mRNA CTD PMID:34845814 CCN2 Human Licochalcone B increases expression EXP 6480464 licochalcone B results in increased expression of CCN2 mRNA CTD PMID:33647349 CCN2 Human limonin decreases expression EXP 6480464 limonin results in decreased expression of CCN2 mRNA CTD PMID:30738134 CCN2 Human linalool multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human linalyl acetate multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human lipopolysaccharide multiple interactions EXP 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of CCN2 mRNA more ... CTD PMID:17965732 more ... CCN2 Human lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of CCN2 mRNA CTD PMID:35811015 CCN2 Human lipopolysaccharide increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of CCN2 mRNA and Lipopolysaccharides results in increased expression of CCN2 protein CTD PMID:17965732 CCN2 Human lipopolysaccharide multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CCN2 protein more ... CTD PMID:24412304 CCN2 Human lovastatin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Lovastatin inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] and Lovastatin inhibits the reaction [Epirubicin results in increased expression of CCN2 mRNA] CTD PMID:22712078 and PMID:28710503 CCN2 Human LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:26054450 CCN2 Human LY294002 multiple interactions ISO Ccn2 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [SMARCA4A protein inhibits the reaction [Glucose results in increased expression of CCN2 mRNA]] CTD PMID:33270355 CCN2 Human manganese(II) chloride increases expression ISO Ccn2 (Mus musculus) 6480464 manganese chloride results in increased expression of CCN2 mRNA CTD PMID:17467022 CCN2 Human manganese(II) chloride increases expression ISO Ccn2 (Rattus norvegicus) 6480464 manganese chloride results in increased expression of CCN2 mRNA CTD PMID:28801915 CCN2 Human manganese(II) chloride increases methylation ISO Ccn2 (Rattus norvegicus) 6480464 manganese chloride results in increased methylation of CCN2 gene CTD PMID:28801915 CCN2 Human mechlorethamine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Mechlorethamine results in increased expression of CCN2 mRNA and Mechlorethamine results in increased expression of CCN2 protein CTD PMID:20883710 and PMID:26273949 CCN2 Human medroxyprogesterone acetate multiple interactions EXP 6480464 [Estradiol co-treated with Bucladesine co-treated with Medroxyprogesterone Acetate] results in increased expression of CCN2 mRNA CTD PMID:20823114 CCN2 Human melatonin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 mRNA] and Melatonin inhibits the reaction [Cyclophosphamide results in decreased expression of CCN2 protein] CTD PMID:36154502 CCN2 Human menadione affects expression EXP 6480464 Vitamin K 3 affects the expression of CCN2 mRNA CTD PMID:20044591 and PMID:23410634 CCN2 Human mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 CCN2 Human mercury dichloride decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Mercuric Chloride results in decreased expression of CCN2 mRNA CTD PMID:16507785 CCN2 Human mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human metformin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Metformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 CCN2 Human methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of CCN2 mRNA CTD PMID:17400583 CCN2 Human methotrexate decreases response to substance EXP 6480464 CCN2 mRNA results in decreased susceptibility to Methotrexate CTD PMID:24154679 CCN2 Human methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of CCN2 mRNA CTD PMID:19192274 CCN2 Human methylisothiazolinone increases expression EXP 6480464 2-methyl-4-isothiazolin-3-one results in increased expression of CCN2 mRNA CTD PMID:31629900 CCN2 Human methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of CCN2 mRNA CTD PMID:23179753 more ... CCN2 Human methylparaben decreases expression EXP 6480464 methylparaben results in decreased expression of CCN2 mRNA CTD PMID:31745603 CCN2 Human methylparaben increases expression EXP 6480464 methylparaben results in increased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human metoprolol increases expression ISO Ccn2 (Mus musculus) 6480464 Metoprolol results in increased expression of CCN2 mRNA CTD PMID:22888001 CCN2 Human metoprolol increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Metoprolol results in increased expression of CCN2 mRNA CTD PMID:22888001 CCN2 Human mifepristone decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Mifepristone results in decreased expression of CCN2 mRNA CTD PMID:25972201 CCN2 Human mono(2-ethylhexyl) phthalate increases expression ISO Ccn2 (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of CCN2 mRNA and mono-(2-ethylhexyl)phthalate results in increased expression of CTGF protein CTD PMID:16809437 and PMID:35143864 CCN2 Human mono(2-ethylhexyl) phthalate multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 STAT5A protein inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CTGF protein] CTD PMID:35143864 CCN2 Human Muraglitazar decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 muraglitazar results in decreased expression of CCN2 mRNA CTD PMID:21515302 CCN2 Human N(5)-ethyl-L-glutamine decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 theanine results in decreased expression of CCN2 protein CTD PMID:25852135 CCN2 Human N(5)-ethyl-L-glutamine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 theanine inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 protein] CTD PMID:25852135 CCN2 Human N-acetyl-L-cysteine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:17270171 CCN2 Human N-methyl-4-phenylpyridinium decreases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of CCN2 mRNA CTD PMID:24810058 CCN2 Human N-methyl-N-nitrosourea decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Methylnitrosourea results in decreased expression of CCN2 mRNA CTD PMID:16525678 CCN2 Human N-methylformamide increases expression ISO Ccn2 (Mus musculus) 6480464 methylformamide analog results in increased expression of CCN2 mRNA and methylformamide results in increased expression of CCN2 mRNA CTD PMID:17040096 CCN2 Human N-nitrosodiethylamine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCN2 mRNA CTD PMID:18164116 CCN2 Human N-nitrosodiethylamine multiple interactions ISO Ccn2 (Mus musculus) 6480464 [1 more ... CTD PMID:21391223 CCN2 Human N-nitrosodiethylamine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of CCN2 mRNA CTD PMID:19638242 CCN2 Human N-nitrosodimethylamine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of CCN2 mRNA and Dimethylnitrosamine results in increased expression of CCN2 protein CTD PMID:15067225 more ... CCN2 Human N-nitrosodimethylamine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 CCN2 protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 mRNA] and CCN2 protein affects the reaction [Dimethylnitrosamine results in increased expression of TGFB1 protein] CTD PMID:17344905 CCN2 Human N-phosphocreatine multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Phosphocreatine promotes the reaction [Doxorubicin results in decreased expression of CTGF mRNA] CTD PMID:37597758 CCN2 Human nicotine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Nicotine results in increased expression of CCN2 protein CTD PMID:22691361 CCN2 Human nitric oxide multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of NOS2 protein] which results in increased abundance of Nitric Oxide] which results in decreased expression of CCN2 protein CTD PMID:24412304 CCN2 Human nitrofen decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 nitrofen results in decreased expression of CCN2 mRNA and nitrofen results in decreased expression of CCN2 protein CTD PMID:20939759 more ... CCN2 Human nitrofen multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 mRNA] and Tretinoin inhibits the reaction [nitrofen results in decreased expression of CCN2 protein] CTD PMID:21258935 CCN2 Human NORCANTHARIDIN decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 norcantharidin results in decreased expression of CCN2 mRNA and norcantharidin results in decreased expression of CCN2 protein CTD PMID:18176075 CCN2 Human NSC 23766 multiple interactions ISO Ccn2 (Mus musculus) 6480464 NSC 23766 inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:28710503 CCN2 Human O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of CCN2 mRNA CTD PMID:32234424 CCN2 Human ochratoxin A increases expression ISO Ccn2 (Rattus norvegicus) 6480464 ochratoxin A results in increased expression of CCN2 mRNA CTD PMID:19717638 CCN2 Human ochratoxin A decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 ochratoxin A results in decreased expression of CCN2 mRNA CTD PMID:23358140 CCN2 Human olaparib multiple interactions ISO Ccn2 (Mus musculus) 6480464 olaparib inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA] CTD PMID:27984176 CCN2 Human oxaliplatin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN2 mRNA CTD PMID:25729387 CCN2 Human oxaliplatin increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Oxaliplatin results in increased expression of CCN2 mRNA CTD PMID:25729387 CCN2 Human p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of CCN2 mRNA CTD PMID:26272509 CCN2 Human p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 CCN2 Human paclitaxel multiple interactions EXP 6480464 [Cisplatin co-treated with Paclitaxel] affects the expression of CCN2 mRNA CTD PMID:20705681 CCN2 Human Paeonol multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 paeonol inhibits the reaction [Doxorubicin results in increased expression of CCN2 mRNA] CTD PMID:31307187 CCN2 Human paracetamol increases expression ISO Ccn2 (Mus musculus) 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:11264010 more ... CCN2 Human paracetamol increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:33387578 CCN2 Human paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of CCN2 mRNA CTD PMID:25458485 CCN2 Human paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CCN2 mRNA CTD PMID:22230336 CCN2 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CCN2 mRNA CTD PMID:21420995 CCN2 Human paracetamol multiple interactions ISO Ccn2 (Mus musculus) 6480464 NOS2 protein inhibits the reaction [Acetaminophen results in increased expression of CCN2 mRNA] more ... CTD PMID:12392966 more ... CCN2 Human paracetamol affects expression ISO Ccn2 (Mus musculus) 6480464 Acetaminophen affects the expression of CCN2 mRNA CTD PMID:15606129 and PMID:17562736 CCN2 Human paraquat multiple interactions EXP 6480464 [CCN2 protein co-treated with Paraquat] affects the expression of MMP2 mRNA more ... CTD PMID:15728566 more ... CCN2 Human paraquat increases secretion ISO Ccn2 (Rattus norvegicus) 6480464 Paraquat results in increased secretion of CCN2 protein CTD PMID:33000210 CCN2 Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of CCN2 mRNA more ... CTD PMID:15728566 more ... CCN2 Human paraquat multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 LY2109761 inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] more ... CTD PMID:23433149 and PMID:33000210 CCN2 Human paraquat increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Paraquat results in increased expression of CCN2 mRNA and Paraquat results in increased expression of CCN2 protein CTD PMID:23433149 more ... CCN2 Human paraquat multiple interactions ISO Ccn2 (Mus musculus) 6480464 ADIPOQ protein inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] more ... CTD PMID:25945502 more ... CCN2 Human paraquat increases expression ISO Ccn2 (Mus musculus) 6480464 Paraquat results in increased expression of CCN2 mRNA and Paraquat results in increased expression of CCN2 protein CTD PMID:12595580 more ... CCN2 Human parathion increases methylation EXP 6480464 Parathion results in increased methylation of CCN2 promoter CTD PMID:22847954 CCN2 Human pentane-2,3-dione increases expression ISO Ccn2 (Rattus norvegicus) 6480464 2 and 3-pentanedione results in increased expression of CCN2 mRNA CTD PMID:25710175 CCN2 Human Pentoxifylline decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Pentoxifylline results in decreased expression of CCN2 mRNA CTD PMID:11788567 CCN2 Human perfluorobutanesulfonic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with ammonium 2 more ... CTD PMID:39141488 CCN2 Human perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human perfluorooctane-1-sulfonic acid increases expression ISO Ccn2 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of CCN2 mRNA CTD PMID:21251948 CCN2 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with ammonium 2 more ... CTD PMID:39141488 CCN2 Human perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of CCN2 mRNA CTD PMID:27153767 CCN2 Human perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of CCN2 protein CTD PMID:26879310 CCN2 Human perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of CCN2 protein CTD PMID:35346789 CCN2 Human perfluorooctanoic acid multiple interactions ISO Ccn2 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with perfluorooctane sulfonic acid co-treated with ammonium 2 more ... CTD PMID:39141488 CCN2 Human phenformin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Phenformin results in decreased expression of CCN2 mRNA CTD PMID:31324951 CCN2 Human phenobarbital increases expression ISO Ccn2 (Mus musculus) 6480464 Phenobarbital results in increased expression of CCN2 mRNA CTD PMID:19270015 CCN2 Human phenobarbital decreases expression EXP 6480464 Phenobarbital results in decreased expression of CCN2 mRNA CTD PMID:19084549 CCN2 Human phenylephrine increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Phenylephrine results in increased expression of CCN2 mRNA and Phenylephrine results in increased expression of CCN2 protein CTD PMID:15276029 CCN2 Human phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of CCN2 mRNA CTD PMID:26272509 CCN2 Human phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of CCN2 mRNA CTD PMID:27188386 CCN2 Human phloroglucinol multiple interactions EXP 6480464 Phloroglucinol analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:26054450 CCN2 Human phorbol 13-acetate 12-myristate multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Tetradecanoylphorbol Acetate co-treated with [Cadmium Chloride results in increased abundance of Cadmium]] affects the expression of CCN2 mRNA CTD PMID:31904401 CCN2 Human phosphane increases expression ISO Ccn2 (Rattus norvegicus) 6480464 phosphine results in increased expression of CTGF mRNA CTD PMID:34427094 CCN2 Human pioglitazone multiple interactions EXP 6480464 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA and Pioglitazone inhibits the reaction [tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA] CTD PMID:20847119 CCN2 Human pioglitazone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Pioglitazone affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:16484506 CCN2 Human pirfenidone multiple interactions ISO Ccn2 (Mus musculus) 6480464 pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:35654123 CCN2 Human pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of CCN2 mRNA and pirinixic acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:19429239 and PMID:19710929 CCN2 Human pirinixic acid increases expression ISO Ccn2 (Mus musculus) 6480464 pirinixic acid results in increased expression of CCN2 mRNA CTD PMID:18301758 and PMID:23811191 CCN2 Human piroxicam decreases expression EXP 6480464 Piroxicam results in decreased expression of CCN2 mRNA CTD PMID:21858171 CCN2 Human platycodin D decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 platycodin D results in decreased expression of CCN2 protein CTD PMID:29595072 CCN2 Human potassium cyanide increases expression ISO Ccn2 (Mus musculus) 6480464 Potassium Cyanide results in increased expression of CCN2 mRNA CTD PMID:33914522 CCN2 Human prednisolone increases expression EXP 6480464 Prednisolone results in increased expression of CCN2 mRNA CTD PMID:19192274 CCN2 Human pregnenolone 16alpha-carbonitrile increases expression ISO Ccn2 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of CCN2 mRNA CTD PMID:28903501 CCN2 Human progesterone affects expression ISO Ccn2 (Mus musculus) 6480464 Progesterone affects the expression of CCN2 mRNA CTD PMID:17251523 CCN2 Human progesterone increases expression ISO Ccn2 (Mus musculus) 6480464 Progesterone results in increased expression of CCN2 mRNA CTD PMID:22238285 CCN2 Human progesterone increases abundance ISO Ccn2 (Mus musculus) 6480464 CCN2 gene mutant form results in increased abundance of Progesterone CTD PMID:21868453 CCN2 Human progesterone multiple interactions ISO Ccn2 (Mus musculus) 6480464 [CCN2 gene mutant form results in increased abundance of Progesterone] which results in increased expression of CASP3 mRNA CTD PMID:21868453 CCN2 Human prostaglandin E2 multiple interactions ISO Ccn2 (Mus musculus) 6480464 [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA] more ... CTD PMID:28434932 CCN2 Human puerarin multiple interactions ISO Ccn2 (Mus musculus) 6480464 puerarin inhibits the reaction [[Dietary Fats co-treated with Dietary Sucrose] results in increased expression of CCN2 mRNA] and puerarin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] CTD PMID:27318789 and PMID:31273855 CCN2 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of CCN2 mRNA CTD PMID:21632981 CCN2 Human quercetin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] more ... CTD PMID:15573758 more ... CCN2 Human quercetin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA] CTD PMID:22915297 CCN2 Human ramipril multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein CTD PMID:31062909 CCN2 Human resveratrol affects expression ISO Ccn2 (Rattus norvegicus) 6480464 Resveratrol affects the expression of CCN2 mRNA CTD PMID:17875610 CCN2 Human resveratrol multiple interactions EXP 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of CCN2 mRNA CTD PMID:23557933 CCN2 Human resveratrol decreases expression EXP 6480464 Resveratrol results in decreased expression of CCN2 mRNA CTD PMID:23224687 CCN2 Human resveratrol multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein more ... CTD PMID:26891083 and PMID:31062909 CCN2 Human rofecoxib multiple interactions ISO Ccn2 (Mus musculus) 6480464 rofecoxib inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 protein] CTD PMID:17565644 CCN2 Human roflumilast multiple interactions EXP 6480464 Roflumilast inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:39197814 CCN2 Human rosmarinic acid decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Rosmarinic Acid results in decreased expression of CCN2 mRNA CTD PMID:28789951 CCN2 Human rosmarinic acid multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Rosmarinic Acid inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] CTD PMID:28789951 CCN2 Human rotenone decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of CCN2 mRNA CTD PMID:28374803 CCN2 Human rutin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 mRNA] and Rutin inhibits the reaction [Isoproterenol results in increased expression of CCN2 protein] CTD PMID:24117263 CCN2 Human S-(1,2-dichlorovinyl)-L-cysteine multiple interactions EXP 6480464 S-(1 and 2-dichlorovinyl)cysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCN2 mRNA] CTD PMID:35811015 CCN2 Human sabinene multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human saralasin multiple interactions EXP 6480464 Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] and Saralasin inhibits the reaction [Paraquat results in increased expression of CCN2 protein] CTD PMID:20035857 CCN2 Human SB 203580 multiple interactions EXP 6480464 SB 203580 analog inhibits the reaction [TGFB1 protein results in increased expression of CCN2 protein] and SB 203580 inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 and PMID:26054450 CCN2 Human SB 203580 decreases expression EXP 6480464 SB 203580 results in decreased expression of CCN2 protein CTD PMID:20864298 CCN2 Human SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 CCN2 Human serpentine asbestos increases expression ISO Ccn2 (Mus musculus) 6480464 Asbestos and Serpentine results in increased expression of CCN2 CTD PMID:19817698 CCN2 Human serpentine asbestos multiple interactions ISO Ccn2 (Mus musculus) 6480464 TGFB1 protein affects the reaction [Asbestos and Serpentine results in increased expression of CCN2] CTD PMID:19817698 CCN2 Human sildenafil citrate multiple interactions ISO Ccn2 (Mus musculus) 6480464 PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA]] and Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA] CTD PMID:25139994 CCN2 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of CCN2 mRNA CTD PMID:25351596 and PMID:27095093 CCN2 Human silicon dioxide increases expression ISO Ccn2 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of CTGF protein CTD PMID:33428986 CCN2 Human silicon dioxide multiple interactions ISO Ccn2 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Silicon Dioxide results in increased expression of CTGF protein] CTD PMID:33428986 CCN2 Human simvastatin multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin inhibits the reaction [TGFB1 results in increased expression of CCN2 mRNA]] more ... CTD PMID:15298857 and PMID:15677772 CCN2 Human simvastatin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Simvastatin results in decreased expression of CCN2 mRNA and Simvastatin results in decreased expression of CCN2 protein CTD PMID:15200425 more ... CCN2 Human simvastatin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 CCN2 Human simvastatin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA] and Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] CTD PMID:19080365 CCN2 Human sirolimus increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Sirolimus results in increased expression of CCN2 mRNA CTD PMID:21865292 CCN2 Human sodium arsenite affects expression ISO Ccn2 (Mus musculus) 6480464 sodium arsenite affects the expression of CCN2 mRNA CTD PMID:16507464 CCN2 Human sodium arsenite decreases expression ISO Ccn2 (Mus musculus) 6480464 sodium arsenite results in decreased expression of CCN2 mRNA CTD PMID:37682722 CCN2 Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CCN2 mRNA CTD PMID:34032870 CCN2 Human sodium arsenite multiple interactions ISO Ccn2 (Mus musculus) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Dietary Fats] results in increased expression of CCN2 protein and [sodium arsenite results in increased abundance of Arsenic] which results in increased expression of CCN2 protein CTD PMID:31238026 CCN2 Human sodium arsenite multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of CCN2 protein] CTD PMID:27889505 CCN2 Human sodium arsenite increases expression ISO Ccn2 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of CCN2 mRNA and sodium arsenite results in increased expression of CCN2 protein CTD PMID:27889505 and PMID:32593899 CCN2 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of CCN2 mRNA CTD PMID:12377979 more ... CCN2 Human sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of CCN2 mRNA CTD PMID:31734321 CCN2 Human sodium dodecyl sulfate decreases expression EXP 6480464 Sodium Dodecyl Sulfate results in decreased expression of CCN2 mRNA CTD PMID:25377654 CCN2 Human sodium tungstate decreases expression EXP 6480464 sodium tungstate(VI) results in decreased expression of CCN2 mRNA CTD PMID:26164860 CCN2 Human sorafenib decreases expression ISO Ccn2 (Mus musculus) 6480464 Sorafenib results in decreased expression of CCN2 mRNA CTD PMID:21360571 CCN2 Human spathulenol multiple interactions EXP 6480464 [beta-thujone co-treated with linalyl acetate co-treated with sabinene co-treated with linalool co-treated with Camphor co-treated with myrcene co-treated with Eucalyptol co-treated with caryophyllene co-treated with spathulenol] results in increased expression of CTGF mRNA CTD PMID:38000518 CCN2 Human sphingosine 1-phosphate increases expression ISO Ccn2 (Mus musculus) 6480464 sphingosine 1-phosphate results in increased expression of CCN2 mRNA CTD PMID:25690654 CCN2 Human sphingosine 1-phosphate increases expression EXP 6480464 sphingosine 1-phosphate results in increased expression of CCN2 mRNA CTD PMID:25690654 CCN2 Human spironolactone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of CCN2 protein] CTD PMID:17278980 CCN2 Human stattic multiple interactions EXP 6480464 stattic inhibits the reaction [IL6 protein results in increased expression of CCN2 mRNA] CTD PMID:25740948 CCN2 Human stattic multiple interactions ISO Ccn2 (Mus musculus) 6480464 stattic inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of CCN2 mRNA] CTD PMID:25740948 CCN2 Human streptozocin increases expression ISO Ccn2 (Mus musculus) 6480464 Streptozocin results in increased expression of CCN2 and Streptozocin results in increased expression of CCN2 protein CTD PMID:19657322 and PMID:24967692 CCN2 Human streptozocin increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of CCN2 mRNA and Streptozocin results in increased expression of CCN2 protein CTD PMID:10026205 more ... CCN2 Human streptozocin multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] promotes the reaction [KLF15 gene mutant form results in increased expression of CCN2 protein] more ... CTD PMID:24707343 more ... CCN2 Human streptozocin multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Resveratrol co-treated with Ramipril] results in decreased expression of CCN2 protein more ... CTD PMID:14586741 more ... CCN2 Human succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of CCN2 mRNA CTD PMID:26378955 CCN2 Human sulforaphane multiple interactions ISO Ccn2 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of CCN2 protein] more ... CTD PMID:24707343 more ... CCN2 Human sulindac sulfide decreases expression EXP 6480464 sulindac sulfide results in decreased expression of CCN2 mRNA CTD PMID:12734198 CCN2 Human sulindac sulfide increases expression EXP 6480464 sulindac sulfide results in increased expression of CCN2 mRNA CTD PMID:16184548 CCN2 Human sunitinib multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Carnitine inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] and SN50 peptide inhibits the reaction [Sunitinib results in increased expression of CCN2 mRNA] CTD PMID:26581635 CCN2 Human sunitinib increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Sunitinib results in increased expression of CCN2 mRNA CTD PMID:26581635 CCN2 Human tacrolimus hydrate multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Tacrolimus inhibits the reaction [Paraquat results in increased expression of CCN2 mRNA] and Tacrolimus inhibits the reaction [Paraquat results in increased secretion of CCN2 protein] CTD PMID:33000210 CCN2 Human tamoxifen increases expression ISO Ccn2 (Mus musculus) 6480464 Tamoxifen results in increased expression of CCN2 mRNA CTD PMID:25123088 CCN2 Human tamoxifen affects expression ISO Ccn2 (Mus musculus) 6480464 Tamoxifen affects the expression of CCN2 mRNA CTD PMID:20937368 CCN2 Human tauroursodeoxycholic acid decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 ursodoxicoltaurine results in decreased expression of CCN2 mRNA CTD PMID:15885361 CCN2 Human tebufenpyrad increases expression EXP 6480464 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in increased expression of CCN2 mRNA CTD PMID:33512557 CCN2 Human temozolomide increases expression EXP 6480464 Temozolomide results in increased expression of CCN2 mRNA CTD PMID:31758290 CCN2 Human terbufos increases methylation EXP 6480464 terbufos results in increased methylation of CCN2 promoter CTD PMID:22847954 CCN2 Human tert-butyl hydroperoxide multiple interactions EXP 6480464 [Pioglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA more ... CTD PMID:20847119 CCN2 Human tert-butyl hydroperoxide affects expression EXP 6480464 tert-Butylhydroperoxide affects the expression of CCN2 mRNA CTD PMID:23410634 CCN2 Human tert-butyl hydroperoxide decreases expression EXP 6480464 tert-Butylhydroperoxide results in decreased expression of CCN2 mRNA CTD PMID:20847119 CCN2 Human testosterone increases expression ISO Ccn2 (Mus musculus) 6480464 Testosterone results in increased expression of CCN2 mRNA CTD PMID:15788153 CCN2 Human testosterone multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of CCN2 mRNA CTD PMID:32741896 CCN2 Human tetrachloromethane multiple interactions ISO Ccn2 (Mus musculus) 6480464 ADIPOQ protein affects the reaction [Carbon Tetrachloride results in increased expression of CCN2 mRNA] more ... CTD PMID:14724832 more ... CCN2 Human tetrachloromethane multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 CCN2 affects the reaction [Carbon Tetrachloride results in increased activity of TGFB1 protein] more ... CTD PMID:16484506 more ... CCN2 Human tetrachloromethane increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of CCN2 mRNA and Carbon Tetrachloride results in increased expression of CCN2 protein CTD PMID:16420518 more ... CCN2 Human tetrachloromethane increases expression ISO Ccn2 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of CCN2 mRNA and Carbon Tetrachloride results in increased expression of CCN2 protein CTD PMID:14724832 more ... CCN2 Human tetracycline increases expression ISO Ccn2 (Mus musculus) 6480464 Tetracycline results in increased expression of CCN2 mRNA CTD PMID:16917069 CCN2 Human tetramethylpyrazine multiple interactions ISO Ccn2 (Mus musculus) 6480464 tetramethylpyrazine inhibits the reaction [Paraquat results in increased expression of CCN2 protein] CTD PMID:30744607 CCN2 Human thioacetamide increases expression ISO Ccn2 (Mus musculus) 6480464 Thioacetamide results in increased expression of CCN2 mRNA CTD PMID:28560358 CCN2 Human thioacetamide multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Coffee inhibits the reaction [Thioacetamide results in increased expression of CCN2 protein] CTD PMID:22899499 CCN2 Human thioacetamide increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of CCN2 mRNA and Thioacetamide results in increased expression of CCN2 protein CTD PMID:22899499 and PMID:34492290 CCN2 Human thioacetamide multiple interactions ISO Ccn2 (Mus musculus) 6480464 [Ethanol co-treated with Thioacetamide] results in increased expression of CCN2 mRNA and TGFBR1 protein promotes the reaction [Thioacetamide results in increased expression of CCN2 mRNA] CTD PMID:21863215 and PMID:28560358 CCN2 Human thiram increases expression EXP 6480464 Thiram results in increased expression of CCN2 mRNA CTD PMID:38568856 CCN2 Human titanium dioxide increases expression ISO Ccn2 (Mus musculus) 6480464 titanium dioxide results in increased expression of CCN2 mRNA CTD PMID:27760801 CCN2 Human topotecan increases expression ISO Ccn2 (Rattus norvegicus) 6480464 Topotecan results in increased expression of CCN2 mRNA CTD PMID:25729387 CCN2 Human topotecan multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 [Oxaliplatin co-treated with Topotecan] results in increased expression of CCN2 mRNA CTD PMID:25729387 CCN2 Human triadimefon decreases expression EXP 6480464 triadimefon results in decreased expression of CTGF mRNA CTD PMID:26705709 CCN2 Human triamcinolone acetonide multiple interactions EXP 6480464 Triamcinolone Acetonide promotes the reaction [Paraquat results in increased expression of CCN2 mRNA] CTD PMID:15728566 CCN2 Human trichloroethene decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Trichloroethylene results in decreased expression of CCN2 mRNA CTD PMID:33387578 CCN2 Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of CCN2 mRNA and trichostatin A results in increased expression of CTGF mRNA CTD PMID:19606018 and PMID:26705709 CCN2 Human triclosan affects expression EXP 6480464 Triclosan affects the expression of CCN2 mRNA CTD PMID:31714634 CCN2 Human triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of CTGF mRNA CTD PMID:34681664 CCN2 Human triphenyl phosphate affects expression ISO Ccn2 (Rattus norvegicus) 6480464 triphenyl phosphate affects the expression of CCN2 mRNA CTD PMID:30589522 CCN2 Human triptonide increases expression ISO Ccn2 (Mus musculus) 6480464 triptonide results in increased expression of CCN2 mRNA CTD PMID:33045310 CCN2 Human troglitazone multiple interactions EXP 6480464 [Troglitazone co-treated with tert-Butylhydroperoxide] results in decreased expression of CCN2 mRNA more ... CTD PMID:17056281 more ... CCN2 Human troglitazone decreases expression EXP 6480464 Troglitazone results in decreased expression of CCN2 mRNA CTD PMID:25572481 CCN2 Human troglitazone increases expression EXP 6480464 Troglitazone results in increased expression of CCN2 mRNA CTD PMID:19140230 CCN2 Human urethane increases expression EXP 6480464 Urethane results in increased expression of CCN2 mRNA CTD PMID:28818685 CCN2 Human ursodeoxycholic acid decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 Ursodeoxycholic Acid results in decreased expression of CCN2 mRNA CTD PMID:15885361 CCN2 Human valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of CCN2 gene CTD PMID:29501571 CCN2 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CCN2 mRNA CTD PMID:23179753 more ... CCN2 Human valproic acid affects expression ISO Ccn2 (Mus musculus) 6480464 Valproic Acid affects the expression of CCN2 mRNA CTD PMID:17292431 and PMID:26072468 CCN2 Human valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of CCN2 mRNA CTD PMID:24935251 CCN2 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of CCN2 mRNA CTD PMID:25979313 and PMID:26072468 CCN2 Human vanillin decreases expression EXP 6480464 vanillin results in decreased expression of CCN2 mRNA CTD PMID:17178418 CCN2 Human verteporfin multiple interactions EXP 6480464 Verteporfin inhibits the reaction [YAP1 protein results in increased expression of CCN2 mRNA] CTD PMID:29725256 CCN2 Human verteporfin multiple interactions ISO Ccn2 (Mus musculus) 6480464 Verteporfin inhibits the reaction [[XMU-MP-1 co-treated with Cadmium Chloride] results in increased expression of CCN2 mRNA] CTD PMID:35027733 CCN2 Human verteporfin decreases expression EXP 6480464 Verteporfin results in decreased expression of CCN2 mRNA CTD PMID:29725256 CCN2 Human vincaleukoblastine affects response to substance EXP 6480464 CCN2 protein affects the susceptibility to Vinblastine CTD PMID:16217747 CCN2 Human vinclozolin affects expression ISO Ccn2 (Rattus norvegicus) 6480464 vinclozolin affects the expression of CCN2 mRNA CTD PMID:19015723 CCN2 Human vinclozolin decreases expression ISO Ccn2 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of CCN2 mRNA CTD PMID:23034163 CCN2 Human vincristine decreases response to substance EXP 6480464 CCN2 mRNA results in decreased susceptibility to Vincristine CTD PMID:24154679 CCN2 Human vitamin D multiple interactions ISO Ccn2 (Mus musculus) 6480464 Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 mRNA] and Vitamin D inhibits the reaction [Ethanol results in increased expression of CCN2 protein] CTD PMID:19280452 CCN2 Human vorinostat increases expression EXP 6480464 Vorinostat results in increased expression of CCN2 mRNA CTD PMID:27188386 CCN2 Human XMU-MP-1 multiple interactions EXP 6480464 [XMU-MP-1 co-treated with pyrazolanthrone co-treated with U 0126] inhibits the reaction [fisetin results in decreased expression of CCN2 protein] and XMU-MP-1 inhibits the reaction [fisetin results in decreased expression of CCN2 protein] CTD PMID:31044527 CCN2 Human XMU-MP-1 multiple interactions ISO Ccn2 (Mus musculus) 6480464 [XMU-MP-1 co-treated with Cadmium Chloride] results in increased expression of CCN2 mRNA and Verteporfin inhibits the reaction [[XMU-MP-1 co-treated with Cadmium Chloride] results in increased expression of CCN2 mRNA] CTD PMID:35027733 CCN2 Human Y-27632 multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] CTD PMID:15200425 CCN2 Human zinc atom multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:19369054 CCN2 Human zinc atom multiple interactions ISO Ccn2 (Mus musculus) 6480464 Zinc inhibits the reaction [Dietary Fats results in increased expression of CCN2 protein] CTD PMID:27370414 CCN2 Human zinc atom multiple interactions EXP 6480464 Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 CCN2 Human zinc dichloride increases expression EXP 6480464 zinc chloride results in increased expression of CCN2 mRNA CTD PMID:35027733 CCN2 Human zinc(0) multiple interactions ISO Ccn2 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of CCN2 protein] CTD PMID:19369054 CCN2 Human zinc(0) multiple interactions EXP 6480464 Zinc inhibits the reaction [Glucose results in increased expression of CCN2 protein] CTD PMID:19369054 CCN2 Human zinc(0) multiple interactions ISO Ccn2 (Mus musculus) 6480464 Zinc inhibits the reaction [Dietary Fats results in increased expression of CCN2 protein] CTD PMID:27370414
