Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: CCN2 (cellular communication network factor 2) Homo sapiens
Analyze
Symbol: CCN2
Name: cellular communication network factor 2
Description: Exhibits protein C-terminus binding activity. Involved in positive regulation of MAPK cascade; positive regulation of cell differentiation; and positive regulation of stress fiber assembly. Colocalizes with the collagen-containing extracellular matrix. Biomarker of ovarian cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCN family member 2; connective tissue growth factor; CTGF; HCS24; hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; insulin-like growth factor-binding protein 8; MGC102839; NOV2
Orthologs:
Mus musculus (house mouse) : Ccn2 (cellular communication network factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccn2 (cellular communication network factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccn2 (cellular communication network factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCN2 (cellular communication network factor 2)
Canis lupus familiaris (dog) : CCN2 (cellular communication network factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccn2 (cellular communication network factor 2)
Sus scrofa (pig) : CCN2 (cellular communication network factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386131,948,176 - 131,951,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376132,269,316 - 132,272,518 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,311,009 - 132,314,211 (-)NCBINCBI36hg18NCBI36
Build 346132,311,017 - 132,314,147NCBI
Celera6133,016,448 - 133,019,647 (-)NCBI
Cytogenetic Map6q23.2NCBI
HuRef6129,844,775 - 129,847,974 (-)NCBIHuRef
CHM1_16132,533,071 - 132,536,270 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CCN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731013
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.