CCN2 (cellular communication network factor 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: CCN2 (cellular communication network factor 2) Homo sapiens
Analyze
Symbol: CCN2
Name: cellular communication network factor 2
RGD ID: 731013
HGNC Page HGNC:2500
Description: Predicted to enable heparin binding activity and integrin binding activity. Involved in positive regulation of MAPK cascade; positive regulation of cell differentiation; and positive regulation of stress fiber assembly. Located in Golgi apparatus. Biomarker of ovarian cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CCN family member 2; connective tissue growth factor; CTGF; HCS24; hypertrophic chondrocyte-specific protein 24; IBP-8; IGF-binding protein 8; IGFBP-8; IGFBP8; insulin-like growth factor-binding protein 8; MGC102839; NOV2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386131,948,176 - 131,951,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6131,948,176 - 131,951,372 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,269,316 - 132,272,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,311,009 - 132,314,211 (-)NCBINCBI36Build 36hg18NCBI36
Build 346132,311,017 - 132,314,147NCBI
Celera6133,016,448 - 133,019,647 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6129,844,775 - 129,847,974 (-)NCBIHuRef
CHM1_16132,533,071 - 132,536,270 (-)NCBICHM1_1
T2T-CHM13v2.06133,143,212 - 133,146,410 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-beta-thujone  (EXP)
(+)-catechin  (EXP)
(-)-epigallocatechin 3-gallate  (ISO)
(20S)-ginsenoside Rg3  (EXP)
(R)-camphor  (EXP)
(R)-carnitine  (ISO)
(R)-linalyl acetate  (EXP)
(S)-nicotine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (ISO)
1,8-cineole  (EXP)
1-naphthyl isothiocyanate  (ISO)
1-nitropyrene  (EXP)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,4,7,8-Pentachlorodibenzofuran  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-butoxyethanol  (ISO)
2-methoxyethanol  (ISO)
2-tert-butylhydroquinone  (ISO)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (EXP)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-dichloroaniline  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-phenylprop-2-enal  (EXP)
4'-epidoxorubicin  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxy-TEMPO  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
6alpha-methylprednisolone  (EXP)
7,12-dimethyltetraphene  (ISO)
acetaldehyde  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrylamide  (EXP)
adenine  (ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
aflatoxin M1  (EXP)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (EXP,ISO)
aldosterone  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-D-galactose  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
Ammothamnine  (ISO)
andrographolide  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antimycin A  (EXP)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP,ISO)
aristolochic acids  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
asbestos  (EXP)
atrazine  (EXP)
bazedoxifene  (EXP)
belinostat  (EXP)
benazepril  (ISO)
benzalkonium chloride  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
beta-D-glucosamine  (ISO)
beta-lapachone  (EXP)
beta-naphthoflavone  (EXP,ISO)
Betanin  (ISO)
bezafibrate  (EXP)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bromobenzene  (ISO)
bucladesine  (EXP)
buta-1,3-diene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
camostat  (ISO)
camphor  (EXP)
candesartan  (ISO)
Candesartan cilexetil  (ISO)
cannabidiol  (EXP)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
carbonyl sulfide  (ISO)
cefaloridine  (ISO)
CGP 52608  (EXP)
chlordecone  (ISO)
chloropicrin  (EXP)
chloroprene  (ISO)
chlorpromazine  (EXP)
choline  (ISO)
chromium(6+)  (EXP)
cisplatin  (EXP,ISO)
clobetasol  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
coenzyme Q10  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (EXP,ISO)
DDT  (ISO)
deoxynivalenol  (EXP)
dexamethasone  (ISO)
Diallyl sulfide  (ISO)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibenzo[a,l]pyrene  (EXP)
dibutyl phthalate  (ISO)
dichloroacetic acid  (EXP,ISO)
dicrotophos  (EXP)
diethyl malate  (EXP)
diiodine  (ISO)
dioxygen  (ISO)
diquat  (ISO)
diuron  (EXP,ISO)
divanadium pentaoxide  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
enalapril  (ISO)
endosulfan  (ISO)
erythromycin estolate  (ISO)
ethanol  (EXP,ISO)
etoposide  (EXP)
fenofibrate  (ISO)
ferulic acid  (ISO)
fipronil  (ISO)
fisetin  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
fonofos  (EXP)
formaldehyde  (EXP)
fructose  (ISO)
fulvestrant  (EXP)
furan  (ISO)
galactose  (ISO)
genistein  (EXP)
gentamycin  (ISO)
glucose  (EXP,ISO)
gypenoside LXXV  (ISO)
hexadecanoic acid  (ISO)
Honokiol  (EXP,ISO)
hydrogen cyanide  (ISO)
hydrogen peroxide  (EXP)
hydrogen sulfide  (ISO)
hydroquinone  (EXP)
idebenone  (ISO)
iloprost  (ISO)
indole-3-methanol  (ISO)
indometacin  (ISO)
irinotecan  (EXP)
isobutanol  (EXP)
isoprenaline  (ISO)
ivermectin  (EXP,ISO)
jaspamide  (EXP,ISO)
L-ascorbic acid 2-phosphate  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
leflunomide  (EXP)
letrozole  (ISO)
Licochalcone A  (EXP)
Licochalcone B  (EXP)
limonin  (EXP)
linalool  (EXP)
linalyl acetate  (EXP)
lipopolysaccharide  (EXP,ISO)
lovastatin  (ISO)
LY294002  (EXP,ISO)
manganese(II) chloride  (ISO)
mechlorethamine  (ISO)
medroxyprogesterone acetate  (EXP)
melatonin  (ISO)
menadione  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (EXP,ISO)
metformin  (ISO)
methotrexate  (EXP)
methylisothiazolinone  (EXP)
methylmercury chloride  (EXP)
methylparaben  (EXP)
metoprolol  (ISO)
mifepristone  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (ISO)
N(5)-ethyl-L-glutamine  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-phosphocreatine  (ISO)
nicotine  (ISO)
nitric oxide  (ISO)
nitrofen  (ISO)
NORCANTHARIDIN  (ISO)
NSC 23766  (ISO)
O-methyleugenol  (EXP)
ochratoxin A  (ISO)
olaparib  (ISO)
oxaliplatin  (ISO)
p-chloromercuribenzoic acid  (EXP)
paclitaxel  (EXP)
Paeonol  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (EXP)
pentane-2,3-dione  (ISO)
Pentoxifylline  (ISO)
perfluorobutanesulfonic acid  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
phenylephrine  (ISO)
phenylmercury acetate  (EXP)
phloroglucinol  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphane  (ISO)
pioglitazone  (EXP,ISO)
pirfenidone  (ISO)
pirinixic acid  (EXP,ISO)
piroxicam  (EXP)
platycodin D  (ISO)
potassium cyanide  (ISO)
prednisolone  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
prostaglandin E2  (ISO)
puerarin  (ISO)
quercetin  (EXP,ISO)
ramipril  (ISO)
resveratrol  (EXP,ISO)
rofecoxib  (ISO)
roflumilast  (EXP)
rosmarinic acid  (ISO)
rotenone  (ISO)
rutin  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
sabinene  (EXP)
saralasin  (EXP)
SB 203580  (EXP)
SB 431542  (EXP)
serpentine asbestos  (ISO)
sildenafil citrate  (ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium dodecyl sulfate  (EXP)
sodium tungstate  (EXP)
sorafenib  (ISO)
spathulenol  (EXP)
sphingosine 1-phosphate  (EXP,ISO)
spironolactone  (ISO)
stattic  (EXP,ISO)
streptozocin  (ISO)
succimer  (EXP)
sulforaphane  (ISO)
sulindac sulfide  (EXP)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tauroursodeoxycholic acid  (ISO)
tebufenpyrad  (EXP)
temozolomide  (EXP)
terbufos  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
tetramethylpyrazine  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
titanium dioxide  (ISO)
topotecan  (ISO)
triadimefon  (EXP)
triamcinolone acetonide  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
urethane  (EXP)
ursodeoxycholic acid  (ISO)
valproic acid  (EXP,ISO)
vanillin  (EXP)
verteporfin  (EXP,ISO)
vincaleukoblastine  (EXP)
vinclozolin  (ISO)
vincristine  (EXP)
vitamin D  (ISO)
vorinostat  (EXP)
XMU-MP-1  (EXP,ISO)
Y-27632  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IEA,ISO)
calcium ion transmembrane import into cytosol  (ISO)
cartilage condensation  (IEA,ISO)
cell adhesion  (IBA,IEA)
cell migration  (IEA,ISO)
cell-matrix adhesion  (IEA,ISO)
cellular response to fatty acid  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to interleukin-13  (ISO)
chondrocyte differentiation  (IEA,ISO)
chondrocyte proliferation  (IEA,ISO)
connective tissue development  (IEA,ISO)
DNA biosynthetic process  (IEA)
epidermis development  (TAS)
extracellular matrix constituent secretion  (ISO)
fibroblast growth factor receptor signaling pathway  (IEA,ISO)
integrin-mediated signaling pathway  (IEA,ISO)
intracellular signal transduction  (ISO)
lung development  (IEA,ISO)
microtubule depolymerization  (ISO)
negative regulation of gene expression  (IEA,ISO)
ossification  (IEA,ISO)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of cardiac muscle contraction  (ISO)
positive regulation of cell activation  (ISO)
positive regulation of cell differentiation  (IBA,IDA)
positive regulation of cell population proliferation  (ISO)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IDA)
positive regulation of G0 to G1 transition  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of JNK cascade  (IDA)
positive regulation of protein phosphorylation  (ISO)
positive regulation of stress fiber assembly  (IDA)
reactive oxygen species metabolic process  (IEA,ISO)
regulation of chondrocyte differentiation  (IEA,ISO)
regulation of developmental process  (IEA)
response to amino acid  (ISO)
response to anoxia  (ISO)
response to estradiol  (ISO)
response to fatty acid  (ISO)
response to mineralocorticoid  (ISO)
response to peptide hormone  (ISO)
response to wounding  (TAS)
signal transduction  (IBA,IEA)
tissue homeostasis  (IEA,ISO)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Myocardial fibrosis and apoptosis, but not inflammation, are present in long-term experimental diabetes. Ares-Carrasco S, etal., Am J Physiol Heart Circ Physiol. 2009 Oct 9.
2. Downregulation of connective tissue growth factor by three-dimensional matrix enhances ovarian carcinoma cell invasion. Barbolina MV, etal., Int J Cancer. 2009 Aug 15;125(4):816-25.
3. Investigating structural and biochemical correlates of ganglion cell dysfunction in streptozotocin-induced diabetic rats. Bui BV, etal., Exp Eye Res. 2009 Jun;88(6):1076-83. Epub 2009 Feb 7.
4. Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems. Champetier S, etal., Am J Physiol Heart Circ Physiol. 2009 Mar;296(3):H669-77. Epub 2008 Dec 26.
5. miR-30a attenuates cardiac fibrosis in rats with myocardial infarction by inhibiting CTGF. Chen L, etal., Exp Ther Med. 2018 May;15(5):4318-4324. doi: 10.3892/etm.2018.5952. Epub 2018 Mar 13.
6. Roflumilast, a phosphodiesterase 4 inhibitor, alleviates bleomycin-induced lung injury. Cortijo J, etal., Br J Pharmacol. 2009 Feb;156(3):534-44.
7. Exposure-dependent increases in IL-1beta, substance P, CTGF, and tendinosis in flexor digitorum tendons with upper extremity repetitive strain injury. Fedorczyk JM, etal., J Orthop Res. 2009 Sep 9.
8. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
9. Peroxisome proliferator-activated receptor-gamma activation attenuates cardiac fibrosis in type 2 diabetic rats: the effect of rosiglitazone on myocardial expression of receptor for advanced glycation end products and of connective tissue growth factor. Ihm SH, etal., Basic Res Cardiol. 2009 Oct 23.
10. Highly Purified Eicosapentaenoic Acid Ethyl Ester Prevents Development of Steatosis and Hepatic Fibrosis in Rats. Kajikawa S, etal., Dig Dis Sci. 2009 Oct 24.
11. Arterial gene transfer of the TGF-beta signalling protein Smad3 induces adaptive remodelling following angioplasty: a role for CTGF. Kundi R, etal., Cardiovasc Res. 2009 Nov 1;84(2):326-35. Epub 2009 Jul 1.
12. XLF-III-43, a novel coumarin-aspirin compound, prevents diabetic nephropathy in rats via inhibiting advanced glycation end products. Li H, etal., Eur J Pharmacol. 2009 Nov 4.
13. Endogenous hydrogen sulfide regulates pulmonary artery collagen remodeling in rats with high pulmonary blood flow. Li X, etal., Exp Biol Med (Maywood). 2009 May;234(5):504-12. Epub 2009 Feb 20.
14. Role of connective tissue growth factor in experimental radiation nephropathy in rats. Liu DG and Wang TM, Chin Med J (Engl). 2008 Oct 5;121(19):1925-31.
15. Coagulation in the mesangial area promotes ECM accumulation through factor V expression in MsPGN in rats. Liu N, etal., Am J Physiol Renal Physiol. 2004 Oct;287(4):F612-20. Epub 2004 Jun 1.
16. Oral levosimendan prevents postinfarct heart failure and cardiac remodeling in diabetic Goto-Kakizaki rats. Louhelainen M, etal., J Hypertens. 2009 Oct;27(10):2094-107.
17. Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Lubel JS, etal., Clin Sci (Lond). 2009 Sep 14;117(11):375-86.
18. Inhibition of connective tissue growth factor by small interfering RNA prevents renal fibrosis in rats undergoing chronic allograft nephropathy. Luo GH, etal., Transplant Proc. 2008 Sep;40(7):2365-9.
19. Targeting renal macrophage accumulation via c-fms kinase reduces tubular apoptosis but fails to modify progressive fibrosis in the obstructed rat kidney. Ma FY, etal., Am J Physiol Renal Physiol. 2009 Jan;296(1):F177-85. Epub 2008 Nov 5.
20. Increased MMP-3 and CTGF expression during lipopolysaccharide-induced dopaminergic neurodegeneration. McClain JA, etal., Neurosci Lett. 2009 Aug 21;460(1):27-31. Epub 2009 May 20.
21. Gene expression studies reveal that DNA damage, vascular perturbation, and inflammation contribute to the pathogenesis of carbonyl sulfide neurotoxicity. Morrison JP, etal., Toxicol Pathol. 2009;37(4):502-11. Epub 2009 Apr 24.
22. Overexpression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 decreases bone density in adult mice and induces dwarfism. Nakanishi T, etal., Biochem Biophys Res Commun 2001 Mar 2;281(3):678-81.
23. Simvastatin attenuates experimental small airway remodelling in rats. Ou XM, etal., Respirology. 2009 Jul;14(5):734-45.
24. Connective tissue growth factor overexpression in cardiomyocytes promotes cardiac hypertrophy and protection against pressure overload. Panek AN, etal., PLoS One. 2009 Aug 25;4(8):e6743.
25. Connective tissue growth factor with a novel fibronectin binding site promotes cell adhesion and migration during rat oval cell activation. Pi L, etal., Hepatology. 2008 Mar;47(3):996-1004.
26. CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling. Pi L, etal., J Cell Commun Signal. 2023 Mar;17(1):137-150. doi: 10.1007/s12079-022-00713-y. Epub 2022 Dec 5.
27. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
28. Irbesartan ameliorates diabetic nephropathy by reducing the expression of connective tissue growth factor and alpha-smooth-muscle actin in the tubulointerstitium of diabetic rats. Ren X, etal., Pharmacology. 2009;83(2):80-7. Epub 2008 Dec 9.
29. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
30. Urinary connective tissue growth factor increases far earlier than histopathological damage and functional deterioration in early chronic renal allograft injury. Shi Y, etal., Scand J Urol Nephrol. 2009;43(5):390-9. doi: 10.3109/00365520903142244.
31. Zinc supplementation partially prevents renal pathological changes in diabetic rats. Tang Y, etal., J Nutr Biochem. 2009 Apr 13.
32. Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature. Thomas M, etal., Synapse. 2009 Oct;63(10):881-94.
33. ADVERSE EFFECTS OF HIGH GLUCOSE AND FREE FATTY ACID ON CARDIOMYOCYTES ARE MEDIATED BY CONNECTIVE TISSUE GROWTH FACTOR. Wang XY, etal., Am J Physiol Cell Physiol. 2009 Jul 22.
34. Protective effect of total aralosides of Aralia elata (Miq) Seem (TASAES) against diabetic cardiomyopathy in rats during the early stage, and possible mechanisms. Xi S, etal., Exp Mol Med. 2009 Aug 31;41(8):538-47.
35. Cloning the full-length cDNA for rat connective tissue growth factor: implications for skeletal development. Xu J, etal., J Cell Biochem 2000 Feb;77(1):103-15.
36. Effect of Corilagin on the miR-21/smad7/ERK signaling pathway in a schistosomiasis-induced hepatic fibrosis mouse model. Yang F, etal., Parasitol Int. 2016 Aug;65(4):308-15. doi: 10.1016/j.parint.2016.03.001. Epub 2016 Mar 2.
37. LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor. Ying L, etal., J Cell Sci. 2009 May 1;122(Pt 9):1441-51. Epub 2009 Apr 14.
38. Increased connective tissue growth factor expression in a rat model of chronic heart allograft rejection. Yuan YC, etal., J Formos Med Assoc. 2009 Mar;108(3):240-6.
39. Transcriptional changes in right ventricular tissues are enriched in the outflow tract compared with the apex during chronic pulmonary embolism in rats. Zagorski J, etal., Physiol Genomics. 2009 Sep 9;39(1):61-71. Epub 2009 Jul 14.
Additional References at PubMed
PMID:1293144   PMID:1334251   PMID:1654338   PMID:1925598   PMID:9054739   PMID:9242708   PMID:9371786   PMID:9927660   PMID:10204117   PMID:10350062   PMID:10457363   PMID:10614647  
PMID:10809757   PMID:11101692   PMID:11502477   PMID:11532378   PMID:11697887   PMID:11744618   PMID:11751417   PMID:11818516   PMID:11855859   PMID:11897682   PMID:11967989   PMID:12016149  
PMID:12036876   PMID:12114504   PMID:12150969   PMID:12217862   PMID:12218048   PMID:12239232   PMID:12297288   PMID:12398938   PMID:12470643   PMID:12477932   PMID:12496395   PMID:12535930  
PMID:12553878   PMID:12571253   PMID:12595495   PMID:12668285   PMID:12760970   PMID:12787426   PMID:12811819   PMID:12831056   PMID:12888575   PMID:12941731   PMID:12951326   PMID:14512169  
PMID:14574404   PMID:14585398   PMID:14633859   PMID:14684735   PMID:14702039   PMID:14758550   PMID:14988298   PMID:14996858   PMID:15003992   PMID:15039132   PMID:15041728   PMID:15045137  
PMID:15053922   PMID:15090860   PMID:15111539   PMID:15113833   PMID:15135656   PMID:15247510   PMID:15255181   PMID:15298857   PMID:15345671   PMID:15377500   PMID:15459777   PMID:15526358  
PMID:15536170   PMID:15598883   PMID:15703175   PMID:15761189   PMID:15761249   PMID:15820145   PMID:15857887   PMID:15940639   PMID:15941869   PMID:15950619   PMID:15956925   PMID:16044512  
PMID:16186174   PMID:16204411   PMID:16247469   PMID:16255854   PMID:16270194   PMID:16291159   PMID:16344560   PMID:16373901   PMID:16457822   PMID:16482098   PMID:16501850   PMID:16528248  
PMID:16543635   PMID:16684954   PMID:16731742   PMID:16790529   PMID:16813525   PMID:16820572   PMID:16858645   PMID:16877704   PMID:16889607   PMID:16899928   PMID:17093396   PMID:17116388  
PMID:17119035   PMID:17170128   PMID:17192487   PMID:17215322   PMID:17224075   PMID:17239539   PMID:17239853   PMID:17375628   PMID:17393107   PMID:17399683   PMID:17399955   PMID:17437852  
PMID:17441427   PMID:17498677   PMID:17550972   PMID:17579708   PMID:17580150   PMID:17602195   PMID:17622321   PMID:17657819   PMID:17671176   PMID:17673559   PMID:17681742   PMID:17765657  
PMID:17786299   PMID:17876891   PMID:17881752   PMID:17908800   PMID:17915216   PMID:17922682   PMID:17944991   PMID:17951630   PMID:17951996   PMID:17996907   PMID:18029348   PMID:18080105  
PMID:18172013   PMID:18212329   PMID:18245529   PMID:18264937   PMID:18266973   PMID:18287089   PMID:18292194   PMID:18319604   PMID:18344285   PMID:18358427   PMID:18395916   PMID:18400984  
PMID:18451226   PMID:18481257   PMID:18596209   PMID:18622762   PMID:18628999   PMID:18639630   PMID:18648180   PMID:18676875   PMID:18683703   PMID:18783549   PMID:18787533   PMID:18805993  
PMID:18835464   PMID:18836231   PMID:18846327   PMID:18922143   PMID:18922980   PMID:18936953   PMID:19016368   PMID:19054816   PMID:19054818   PMID:19069651   PMID:19096030   PMID:19153601  
PMID:19179545   PMID:19208517   PMID:19210343   PMID:19218111   PMID:19233176   PMID:19243500   PMID:19247157   PMID:19253834   PMID:19277979   PMID:19298220   PMID:19301259   PMID:19322201  
PMID:19333718   PMID:19378419   PMID:19409809   PMID:19429239   PMID:19453261   PMID:19485899   PMID:19494553   PMID:19549692   PMID:19565505   PMID:19589256   PMID:19641518   PMID:19657322  
PMID:19670427   PMID:19673024   PMID:19724859   PMID:19730442   PMID:19762080   PMID:19764552   PMID:19764567   PMID:19789190   PMID:19822645   PMID:19861250   PMID:19863391   PMID:19890996  
PMID:19893244   PMID:19895313   PMID:19922639   PMID:19955828   PMID:20004937   PMID:20008146   PMID:20015945   PMID:20018872   PMID:20032097   PMID:20032117   PMID:20050020   PMID:20053285  
PMID:20056838   PMID:20117462   PMID:20162579   PMID:20180416   PMID:20201953   PMID:20222112   PMID:20237235   PMID:20237496   PMID:20238043   PMID:20305691   PMID:20453000   PMID:20522428  
PMID:20522536   PMID:20576680   PMID:20613589   PMID:20628624   PMID:20660557   PMID:20685720   PMID:20689330   PMID:20697347   PMID:20731800   PMID:20814177   PMID:20840672   PMID:20966418  
PMID:20971063   PMID:21054221   PMID:21071938   PMID:21081514   PMID:21098624   PMID:21166920   PMID:21209863   PMID:21236242   PMID:21245951   PMID:21245987   PMID:21265091   PMID:21349946  
PMID:21352962   PMID:21424084   PMID:21455569   PMID:21484860   PMID:21501375   PMID:21503841   PMID:21548990   PMID:21558398   PMID:21569762   PMID:21576830   PMID:21609573   PMID:21609598  
PMID:21611193   PMID:21629692   PMID:21654839   PMID:21659659   PMID:21673687   PMID:21747166   PMID:21760921   PMID:21771732   PMID:21784839   PMID:21800344   PMID:21864521   PMID:21873635  
PMID:21907704   PMID:21927029   PMID:21928342   PMID:21946149   PMID:21955589   PMID:22045431   PMID:22099397   PMID:22134873   PMID:22199357   PMID:22205539   PMID:22328559   PMID:22335903  
PMID:22340243   PMID:22350758   PMID:22363806   PMID:22395513   PMID:22416876   PMID:22422617   PMID:22438586   PMID:22454511   PMID:22466886   PMID:22516997   PMID:22532143   PMID:22533709  
PMID:22539964   PMID:22576977   PMID:22586581   PMID:22611323   PMID:22684333   PMID:22699679   PMID:22795353   PMID:22814105   PMID:22846210   PMID:22906474   PMID:22918238   PMID:22964303  
PMID:23029004   PMID:23044205   PMID:23055574   PMID:23056332   PMID:23061738   PMID:23073116   PMID:23108098   PMID:23142580   PMID:23175185   PMID:23227240   PMID:23274856   PMID:23280549  
PMID:23284892   PMID:23307318   PMID:23323010   PMID:23368866   PMID:23383241   PMID:23390502   PMID:23414517   PMID:23414795   PMID:23435419   PMID:23454256   PMID:23494140   PMID:23501329  
PMID:23508392   PMID:23530034   PMID:23564449   PMID:23567513   PMID:23582094   PMID:23593935   PMID:23631855   PMID:23648563   PMID:23663495   PMID:23681229   PMID:23687336   PMID:23727026  
PMID:23741006   PMID:23755163   PMID:23772794   PMID:23824844   PMID:23847295   PMID:23988606   PMID:24005672   PMID:24014274   PMID:24035571   PMID:24074434   PMID:24079812   PMID:24090133  
PMID:24112732   PMID:24121259   PMID:24122827   PMID:24146089   PMID:24154679   PMID:24269276   PMID:24413988   PMID:24462773   PMID:24464580   PMID:24464932   PMID:24485923   PMID:24503185  
PMID:24560449   PMID:24577260   PMID:24597264   PMID:24676352   PMID:24689870   PMID:24700237   PMID:24703458   PMID:24755068   PMID:24758915   PMID:24828686   PMID:24882759   PMID:24933320  
PMID:24973271   PMID:24985492   PMID:25003330   PMID:25030555   PMID:25111595   PMID:25121739   PMID:25126747   PMID:25150958   PMID:25203810   PMID:25261584   PMID:25341039   PMID:25349161  
PMID:25384022   PMID:25478966   PMID:25495560   PMID:25501363   PMID:25502877   PMID:25601519   PMID:25647524   PMID:25704370   PMID:25727481   PMID:25727552   PMID:25738829   PMID:25761878  
PMID:25779637   PMID:25847009   PMID:25847507   PMID:25899830   PMID:25916872   PMID:25940705   PMID:25955392   PMID:26138615   PMID:26171399   PMID:26192087   PMID:26218313   PMID:26318291  
PMID:26421309   PMID:26498181   PMID:26575166   PMID:26577677   PMID:26707502   PMID:26714814   PMID:26719893   PMID:26739296   PMID:26804166   PMID:26894649   PMID:26909983   PMID:27036370  
PMID:27044368   PMID:27075467   PMID:27155083   PMID:27179776   PMID:27248471   PMID:27249027   PMID:27279555   PMID:27284727   PMID:27364355   PMID:27365368   PMID:27390086   PMID:27392496  
PMID:27393180   PMID:27403934   PMID:27421245   PMID:27486656   PMID:27600173   PMID:27633176   PMID:27662798   PMID:27704689   PMID:27721022   PMID:27771733   PMID:27806300   PMID:28005267  
PMID:28067893   PMID:28208216   PMID:28327460   PMID:28330503   PMID:28390067   PMID:28438434   PMID:28460577   PMID:28463604   PMID:28470428   PMID:28478800   PMID:28514442   PMID:28545716  
PMID:28617438   PMID:28731126   PMID:28798388   PMID:28815607   PMID:28837877   PMID:28870205   PMID:28927757   PMID:28931920   PMID:28977597   PMID:29049376   PMID:29100790   PMID:29145495  
PMID:29166915   PMID:29271992   PMID:29339038   PMID:29483593   PMID:29516637   PMID:29574063   PMID:29620147   PMID:29669735   PMID:29739987   PMID:29748618   PMID:29800920   PMID:29861095  
PMID:29885461   PMID:29902535   PMID:29903770   PMID:29967264   PMID:30142763   PMID:30232710   PMID:30262666   PMID:30317661   PMID:30365097   PMID:30383775   PMID:30426494   PMID:30690026  
PMID:30693641   PMID:30695033   PMID:30697920   PMID:30841458   PMID:30900421   PMID:31004409   PMID:31073205   PMID:31086050   PMID:31124308   PMID:31198002   PMID:31262970   PMID:31285444  
PMID:31298008   PMID:31381269   PMID:31451010   PMID:31559693   PMID:31559874   PMID:31578579   PMID:31610176   PMID:31773302   PMID:31922209   PMID:32016800   PMID:32024900   PMID:32054109  
PMID:32120837   PMID:32134425   PMID:32210715   PMID:32316324   PMID:32322062   PMID:32554753   PMID:32705221   PMID:32885819   PMID:33048316   PMID:33087801   PMID:33098545   PMID:33260349  
PMID:33283725   PMID:33358742   PMID:33426067   PMID:33431336   PMID:33594198   PMID:33629293   PMID:33662577   PMID:33692467   PMID:33760200   PMID:33828075   PMID:33877553   PMID:33961781  
PMID:33962151   PMID:34011384   PMID:34096606   PMID:34122421   PMID:34132366   PMID:34204856   PMID:34296783   PMID:34314740   PMID:34601016   PMID:34628139   PMID:34702315   PMID:34732716  
PMID:34784912   PMID:34812907   PMID:34826606   PMID:35013218   PMID:35316957   PMID:35395768   PMID:35441763   PMID:35696571   PMID:35713503   PMID:35876037   PMID:35914814   PMID:35921911  
PMID:35944360   PMID:36068594   PMID:36158888   PMID:36209585   PMID:36210625   PMID:36504062   PMID:36529291   PMID:36672237   PMID:37002970   PMID:37330435   PMID:37433992   PMID:37640791  
PMID:37689702   PMID:37741976   PMID:38134555   PMID:38167009   PMID:38602559   PMID:39238192   PMID:39414788   PMID:39470347  


Genomics

Comparative Map Data
CCN2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386131,948,176 - 131,951,372 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6131,948,176 - 131,951,372 (-)EnsemblGRCh38hg38GRCh38
GRCh376132,269,316 - 132,272,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366132,311,009 - 132,314,211 (-)NCBINCBI36Build 36hg18NCBI36
Build 346132,311,017 - 132,314,147NCBI
Celera6133,016,448 - 133,019,647 (-)NCBICelera
Cytogenetic Map6q23.2NCBI
HuRef6129,844,775 - 129,847,974 (-)NCBIHuRef
CHM1_16132,533,071 - 132,536,270 (-)NCBICHM1_1
T2T-CHM13v2.06133,143,212 - 133,146,410 (-)NCBIT2T-CHM13v2.0
Ccn2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391024,471,340 - 24,474,581 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1024,471,340 - 24,474,581 (+)EnsemblGRCm39 Ensembl
GRCm381024,595,442 - 24,598,683 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1024,595,442 - 24,598,683 (+)EnsemblGRCm38mm10GRCm38
MGSCv371024,315,248 - 24,318,489 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361024,284,923 - 24,288,096 (+)NCBIMGSCv36mm8
Celera1025,537,033 - 25,540,272 (+)NCBICelera
Cytogenetic Map10A4NCBI
cM Map1011.84NCBI
Ccn2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8122,621,498 - 22,624,614 (-)NCBIGRCr8
mRatBN7.2120,802,199 - 20,805,315 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl120,802,199 - 20,805,734 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx120,578,855 - 20,581,971 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0126,578,869 - 26,581,985 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0120,778,746 - 20,781,863 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0121,851,657 - 21,854,773 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl121,851,660 - 21,854,773 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0123,331,544 - 23,334,660 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4121,327,099 - 21,330,215 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1121,328,460 - 21,331,568 (-)NCBI
Celera119,554,327 - 19,557,443 (-)NCBICelera
Cytogenetic Map1p12NCBI
Ccn2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543612,522,944 - 12,526,480 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543612,523,602 - 12,526,986 (-)NCBIChiLan1.0ChiLan1.0
CCN2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25151,935,526 - 151,947,055 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16149,842,461 - 149,845,654 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06129,729,572 - 129,733,113 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16133,836,319 - 133,839,017 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6133,836,319 - 133,842,077 (-)Ensemblpanpan1.1panPan2
CCN2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1125,508,082 - 25,511,058 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl125,507,662 - 25,510,145 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,004,899 - 26,007,816 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0124,930,014 - 24,932,944 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl124,930,014 - 24,933,489 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1124,975,729 - 24,978,649 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0124,865,809 - 24,868,736 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0125,137,679 - 25,140,601 (-)NCBIUU_Cfam_GSD_1.0
Ccn2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946120,263,340 - 120,266,574 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493656042,537 - 45,807 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493656042,561 - 45,748 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCN2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl131,674,394 - 31,677,691 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1131,674,398 - 31,677,697 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2135,134,660 - 35,137,098 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCN2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11341,613,838 - 41,617,010 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1341,613,798 - 41,617,651 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604013,786,737 - 13,789,973 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ccn2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247536,023,069 - 6,024,833 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247536,022,033 - 6,024,866 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CCN2
32 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6q21-23.2(chr6:108944899-132067720)x1 copy number loss See cases [RCV000051196] Chr6:108944899..132067720 [GRCh38]
Chr6:109266102..132388860 [GRCh37]
Chr6:109372795..132430553 [NCBI36]
Chr6:6q21-23.2
pathogenic
GRCh38/hg38 6q13-24.1(chr6:74382807-142040500)x3 copy number gain See cases [RCV000139729] Chr6:74382807..142040500 [GRCh38]
Chr6:75092523..142361637 [GRCh37]
Chr6:75149243..142403330 [NCBI36]
Chr6:6q13-24.1
pathogenic
GRCh38/hg38 6q22.33-23.2(chr6:129191313-132131620)x1 copy number loss See cases [RCV000142349] Chr6:129191313..132131620 [GRCh38]
Chr6:129512458..132452760 [GRCh37]
Chr6:129554151..132494453 [NCBI36]
Chr6:6q22.33-23.2
likely pathogenic
GRCh38/hg38 6q22.32-23.2(chr6:126494533-132497855)x1 copy number loss See cases [RCV000142805] Chr6:126494533..132497855 [GRCh38]
Chr6:126815679..132818994 [GRCh37]
Chr6:126857372..132860687 [NCBI36]
Chr6:6q22.32-23.2
likely pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q21-23.2(chr6:112939290-132327952)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626432] Chr6:112939290..132327952 [GRCh37]
Chr6:6q21-23.2
drug response
NM_001901.4(CCN2):c.998A>G (p.Asn333Ser) single nucleotide variant not specified [RCV004297553] Chr6:131949316 [GRCh38]
Chr6:132270456 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.61A>C (p.Ser21Arg) single nucleotide variant not specified [RCV004308454] Chr6:131951112 [GRCh38]
Chr6:132272252 [GRCh37]
Chr6:6q23.2
uncertain significance
GRCh37/hg19 6q23.2-23.3(chr6:131388023-137469640)x1 copy number loss not provided [RCV000682724] Chr6:131388023..137469640 [GRCh37]
Chr6:6q23.2-23.3
pathogenic
GRCh37/hg19 6q23.2-23.3(chr6:132002460-137160850)x1 copy number loss not provided [RCV000682725] Chr6:132002460..137160850 [GRCh37]
Chr6:6q23.2-23.3
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27
pathogenic
GRCh37/hg19 6q23.2(chr6:131957855-132424554)x3 copy number gain not provided [RCV000746036] Chr6:131957855..132424554 [GRCh37]
Chr6:6q23.2
benign
NM_001901.4(CCN2):c.645G>A (p.Met215Ile) single nucleotide variant not provided [RCV000902331] Chr6:131950057 [GRCh38]
Chr6:132271197 [GRCh37]
Chr6:6q23.2
likely benign
GRCh37/hg19 6q22.33-23.2(chr6:129513837-132618991) copy number loss not provided [RCV000767715] Chr6:129513837..132618991 [GRCh37]
Chr6:6q22.33-23.2
likely pathogenic
NM_001901.4(CCN2):c.304C>T (p.Pro102Ser) single nucleotide variant not provided [RCV000918195] Chr6:131950529 [GRCh38]
Chr6:132271669 [GRCh37]
Chr6:6q23.2
likely benign
GRCh37/hg19 6q23.2(chr6:131673206-132706248)x1 copy number loss not provided [RCV000848451] Chr6:131673206..132706248 [GRCh37]
Chr6:6q23.2
uncertain significance
GRCh37/hg19 6q23.2(chr6:131958069-132444234)x3 copy number gain not provided [RCV000848075] Chr6:131958069..132444234 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.690A>T (p.Leu230=) single nucleotide variant not provided [RCV000933535] Chr6:131950012 [GRCh38]
Chr6:132271152 [GRCh37]
Chr6:6q23.2
likely benign
NM_001901.4(CCN2):c.290-6C>T single nucleotide variant not provided [RCV000949926] Chr6:131950549 [GRCh38]
Chr6:132271689 [GRCh37]
Chr6:6q23.2
benign
NM_001901.4(CCN2):c.915C>T (p.Phe305=) single nucleotide variant not provided [RCV000908512] Chr6:131949399 [GRCh38]
Chr6:132270539 [GRCh37]
Chr6:6q23.2
likely benign
NM_001901.4(CCN2):c.67-4G>A single nucleotide variant not provided [RCV000963874] Chr6:131950996 [GRCh38]
Chr6:132272136 [GRCh37]
Chr6:6q23.2
likely benign
NM_001901.4(CCN2):c.520G>A (p.Val174Met) single nucleotide variant not specified [RCV004609903] Chr6:131950313 [GRCh38]
Chr6:132271453 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.697C>A (p.Gln233Lys) single nucleotide variant not specified [RCV004299032] Chr6:131950005 [GRCh38]
Chr6:132271145 [GRCh37]
Chr6:6q23.2
uncertain significance
Single allele deletion Interstitial 6q microdeletion syndrome [RCV002280353] Chr6:115941808..133892653 [GRCh38]
Chr6:6q22.1-23.2
pathogenic
GRCh37/hg19 6q23.2(chr6:131958038-132444269)x3 copy number gain not provided [RCV001834442] Chr6:131958038..132444269 [GRCh37]
Chr6:6q23.2
uncertain significance
GRCh37/hg19 6q23.1-23.3(chr6:130769034-136009217)x1 copy number loss not provided [RCV001829086] Chr6:130769034..136009217 [GRCh37]
Chr6:6q23.1-23.3
pathogenic
NC_000006.12:g.131688637_132215008del deletion Arterial calcification, generalized, of infancy, 1 [RCV002273892] Chr6:131688637..132215008 [GRCh38]
Chr6:6q23.2
pathogenic
NM_001901.4(CCN2):c.112G>C (p.Glu38Gln) single nucleotide variant not specified [RCV004269440] Chr6:131950947 [GRCh38]
Chr6:132272087 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.932A>G (p.Glu311Gly) single nucleotide variant not specified [RCV004248051] Chr6:131949382 [GRCh38]
Chr6:132270522 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.884C>T (p.Pro295Leu) single nucleotide variant not specified [RCV004274642] Chr6:131949430 [GRCh38]
Chr6:132270570 [GRCh37]
Chr6:6q23.2
uncertain significance
GRCh37/hg19 6q22.31-23.3(chr6:120218852-137160850)x1 copy number loss not provided [RCV003482930] Chr6:120218852..137160850 [GRCh37]
Chr6:6q22.31-23.3
pathogenic
GRCh37/hg19 6q23.2-24.2(chr6:131569837-145572239)x3 copy number gain not specified [RCV003986663] Chr6:131569837..145572239 [GRCh37]
Chr6:6q23.2-24.2
pathogenic
GRCh37/hg19 6q22.31-25.3(chr6:119840686-156623091)x3 copy number gain not specified [RCV003986631] Chr6:119840686..156623091 [GRCh37]
Chr6:6q22.31-25.3
pathogenic
NM_001901.4(CCN2):c.124C>G (p.Arg42Gly) single nucleotide variant not specified [RCV004430601] Chr6:131950935 [GRCh38]
Chr6:132272075 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.111C>A (p.Asp37Glu) single nucleotide variant not specified [RCV004430600] Chr6:131950948 [GRCh38]
Chr6:132272088 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.181G>A (p.Ala61Thr) single nucleotide variant not specified [RCV004430605] Chr6:131950878 [GRCh38]
Chr6:132272018 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.821C>A (p.Thr274Asn) single nucleotide variant not specified [RCV004430615] Chr6:131949493 [GRCh38]
Chr6:132270633 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.90C>G (p.Ser30Arg) single nucleotide variant not specified [RCV004430618] Chr6:131950969 [GRCh38]
Chr6:132272109 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.514C>G (p.Gln172Glu) single nucleotide variant not specified [RCV004430611] Chr6:131950319 [GRCh38]
Chr6:132271459 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.765G>T (p.Lys255Asn) single nucleotide variant not specified [RCV004430614] Chr6:131949549 [GRCh38]
Chr6:132270689 [GRCh37]
Chr6:6q23.2
uncertain significance
GRCh37/hg19 6q22.33-23.2(chr6:129969121-132499298)x1 copy number loss not provided [RCV004577479] Chr6:129969121..132499298 [GRCh37]
Chr6:6q22.33-23.2
uncertain significance
NM_001901.4(CCN2):c.415A>G (p.Met139Val) single nucleotide variant not specified [RCV004430608] Chr6:131950418 [GRCh38]
Chr6:132271558 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.489G>T (p.Glu163Asp) single nucleotide variant not specified [RCV004430609] Chr6:131950344 [GRCh38]
Chr6:132271484 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.49C>A (p.Leu17Ile) single nucleotide variant not specified [RCV004430610] Chr6:131951124 [GRCh38]
Chr6:132272264 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.15T>A (p.Ser5Arg) single nucleotide variant not specified [RCV004430604] Chr6:131951158 [GRCh38]
Chr6:132272298 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.212G>A (p.Arg71His) single nucleotide variant not specified [RCV004430606] Chr6:131950847 [GRCh38]
Chr6:132271987 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.90C>A (p.Ser30Arg) single nucleotide variant not specified [RCV004430617] Chr6:131950969 [GRCh38]
Chr6:132272109 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.134C>T (p.Ala45Val) single nucleotide variant not specified [RCV004430602] Chr6:131950925 [GRCh38]
Chr6:132272065 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.227C>T (p.Pro76Leu) single nucleotide variant not specified [RCV004430607] Chr6:131950832 [GRCh38]
Chr6:132271972 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.622G>A (p.Ala208Thr) single nucleotide variant not specified [RCV004430612] Chr6:131950080 [GRCh38]
Chr6:132271220 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.904C>G (p.Pro302Ala) single nucleotide variant not specified [RCV004430616] Chr6:131949410 [GRCh38]
Chr6:132270550 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.100C>G (p.Arg34Gly) single nucleotide variant not specified [RCV004430599] Chr6:131950959 [GRCh38]
Chr6:132272099 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.156C>G (p.Asp52Glu) single nucleotide variant not specified [RCV004430603] Chr6:131950903 [GRCh38]
Chr6:132272043 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.114G>C (p.Glu38Asp) single nucleotide variant not specified [RCV004609904] Chr6:131950945 [GRCh38]
Chr6:132272085 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.106C>T (p.Pro36Ser) single nucleotide variant not specified [RCV004604780] Chr6:131950953 [GRCh38]
Chr6:132272093 [GRCh37]
Chr6:6q23.2
uncertain significance
NM_001901.4(CCN2):c.14G>T (p.Ser5Ile) single nucleotide variant not provided [RCV004575991] Chr6:131951159 [GRCh38]
Chr6:132272299 [GRCh37]
Chr6:6q23.2
uncertain significance
NC_000006.11:g.(?_131894423)_(133849943_?)del deletion not provided [RCV004578838] Chr6:131894423..133849943 [GRCh37]
Chr6:6q23.2
pathogenic
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR19Ahsa-miR-19a-3pMirecordsexternal_info{changed}NA20305691
MIR18Ahsa-miR-18a-5pMirtarbaseexternal_infoWestern blot//Microarray//Northern blot//LuciferasFunctional MTI16331254
MIR18Ahsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19233176
MIR18Ahsa-miR-18a-3pMirecordsexternal_info{changed}NA20305691
MIR145hsa-miR-145-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23390502

Predicted Target Of
Summary Value
Count of predictions:448
Count of miRNA genes:355
Interacting mature miRNAs:400
Transcripts:ENST00000367976
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH35874  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,688 - 132,269,851UniSTSGRCh37
Build 366132,311,381 - 132,311,544RGDNCBI36
Celera6133,016,820 - 133,016,981RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,147 - 129,845,308UniSTS
GeneMap99-GB4 RH Map6529.62UniSTS
RH18002  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,418 - 132,269,608UniSTSGRCh37
Build 366132,311,111 - 132,311,301RGDNCBI36
Celera6133,016,550 - 133,016,740RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,877 - 129,845,067UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
NCBI RH Map61538.9UniSTS
ECD02742  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,272,781 - 132,273,599UniSTSGRCh37
Build 366132,314,474 - 132,315,292RGDNCBI36
Celera6133,019,910 - 133,020,728RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,848,237 - 129,849,055UniSTS
ECD03031  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,642 - 132,274,450UniSTSGRCh37
Build 366132,315,335 - 132,316,143RGDNCBI36
Celera6133,020,771 - 133,021,579RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,849,098 - 129,849,906UniSTS
ECD03619  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,850 - 132,270,638UniSTSGRCh37
Build 366132,311,543 - 132,312,331RGDNCBI36
Celera6133,016,980 - 133,017,768RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,307 - 129,846,095UniSTS
ECD04257  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,664 - 132,271,433UniSTSGRCh37
Build 366132,312,357 - 132,313,126RGDNCBI36
Celera6133,017,794 - 133,018,562RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,846,121 - 129,846,889UniSTS
ECD10947  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,106 - 132,269,692UniSTSGRCh37
Build 366132,310,799 - 132,311,385RGDNCBI36
Celera6133,016,238 - 133,016,824RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,565 - 129,845,151UniSTS
ECD16754  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,271,545 - 132,271,971UniSTSGRCh37
Build 366132,313,238 - 132,313,664RGDNCBI36
Celera6133,018,674 - 133,019,100RGD
Cytogenetic Map6q23.1UniSTS
ECD22450  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,272,475 - 132,272,693UniSTSGRCh37
Build 366132,314,168 - 132,314,386RGDNCBI36
Celera6133,019,604 - 133,019,822RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,847,931 - 129,848,149UniSTS
REN29375  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,268,853 - 132,269,120UniSTSGRCh37
Build 366132,310,546 - 132,310,813RGDNCBI36
Celera6133,015,985 - 133,016,252RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,312 - 129,844,579UniSTS
REN29376  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,117 - 132,269,378UniSTSGRCh37
Build 366132,310,810 - 132,311,071RGDNCBI36
Celera6133,016,249 - 133,016,510RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,576 - 129,844,837UniSTS
REN29377  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,354 - 132,269,599UniSTSGRCh37
Build 366132,311,047 - 132,311,292RGDNCBI36
Celera6133,016,486 - 133,016,731RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,813 - 129,845,058UniSTS
REN29378  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,585 - 132,269,850UniSTSGRCh37
Build 366132,311,278 - 132,311,543RGDNCBI36
Celera6133,016,717 - 133,016,980RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,044 - 129,845,307UniSTS
REN29379  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,847 - 132,270,083UniSTSGRCh37
Build 366132,311,540 - 132,311,776RGDNCBI36
Celera6133,016,977 - 133,017,213RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,304 - 129,845,540UniSTS
REN29380  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,044 - 132,270,282UniSTSGRCh37
Build 366132,311,737 - 132,311,975RGDNCBI36
Celera6133,017,174 - 133,017,412RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,501 - 129,845,739UniSTS
REN29381  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,259 - 132,270,505UniSTSGRCh37
Build 366132,311,952 - 132,312,198RGDNCBI36
Celera6133,017,389 - 133,017,635RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,716 - 129,845,962UniSTS
REN29382  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,500 - 132,270,762UniSTSGRCh37
Build 366132,312,193 - 132,312,455RGDNCBI36
Celera6133,017,630 - 133,017,891RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,957 - 129,846,218UniSTS
REN29383  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,751 - 132,271,001UniSTSGRCh37
Build 366132,312,444 - 132,312,694RGDNCBI36
Celera6133,017,880 - 133,018,130RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,846,207 - 129,846,457UniSTS
REN29384  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,937 - 132,271,181UniSTSGRCh37
Build 366132,312,630 - 132,312,874RGDNCBI36
Celera6133,018,066 - 133,018,310RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,846,393 - 129,846,637UniSTS
REN29385  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,271,160 - 132,271,417UniSTSGRCh37
Build 366132,312,853 - 132,313,110RGDNCBI36
Celera6133,018,289 - 133,018,546RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,846,616 - 129,846,873UniSTS
REN29386  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,271,407 - 132,271,664UniSTSGRCh37
Build 366132,313,100 - 132,313,357RGDNCBI36
Celera6133,018,536 - 133,018,793RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,846,863 - 129,847,120UniSTS
REN29387  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,271,614 - 132,271,838UniSTSGRCh37
Build 366132,313,307 - 132,313,531RGDNCBI36
Celera6133,018,743 - 133,018,967RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,847,070 - 129,847,294UniSTS
REN29388  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,271,748 - 132,271,972UniSTSGRCh37
Build 366132,313,441 - 132,313,665RGDNCBI36
Celera6133,018,877 - 133,019,101RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,847,204 - 129,847,428UniSTS
REN29389  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,272,465 - 132,272,690UniSTSGRCh37
Build 366132,314,158 - 132,314,383RGDNCBI36
Celera6133,019,594 - 133,019,819RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,847,921 - 129,848,146UniSTS
REN29390  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,272,667 - 132,272,918UniSTSGRCh37
Build 366132,314,360 - 132,314,611RGDNCBI36
Celera6133,019,796 - 133,020,047RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,848,123 - 129,848,374UniSTS
REN29391  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,272,909 - 132,273,157UniSTSGRCh37
Build 366132,314,602 - 132,314,850RGDNCBI36
Celera6133,020,038 - 133,020,286RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,848,365 - 129,848,613UniSTS
REN29392  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,143 - 132,273,405UniSTSGRCh37
Build 366132,314,836 - 132,315,098RGDNCBI36
Celera6133,020,272 - 133,020,534RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,848,599 - 129,848,861UniSTS
REN29393  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,396 - 132,273,633UniSTSGRCh37
Build 366132,315,089 - 132,315,326RGDNCBI36
Celera6133,020,525 - 133,020,762RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,848,852 - 129,849,089UniSTS
REN29394  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,607 - 132,273,846UniSTSGRCh37
Build 366132,315,300 - 132,315,539RGDNCBI36
Celera6133,020,736 - 133,020,975RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,849,063 - 129,849,302UniSTS
REN29395  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,824 - 132,274,052UniSTSGRCh37
Build 366132,315,517 - 132,315,745RGDNCBI36
Celera6133,020,953 - 133,021,181RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,849,280 - 129,849,508UniSTS
REN29396  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,273,998 - 132,274,268UniSTSGRCh37
Build 366132,315,691 - 132,315,961RGDNCBI36
Celera6133,021,127 - 133,021,397RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,849,454 - 129,849,724UniSTS
REN29397  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,274,238 - 132,274,465UniSTSGRCh37
Build 366132,315,931 - 132,316,158RGDNCBI36
Celera6133,021,367 - 133,021,594RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,849,694 - 129,849,921UniSTS
D6S2424  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,635 - 132,269,864UniSTSGRCh37
Build 366132,311,328 - 132,311,557RGDNCBI36
Celera6133,016,767 - 133,016,994RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,094 - 129,845,321UniSTS
STS-X78947  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,432 - 132,269,561UniSTSGRCh37
Build 366132,311,125 - 132,311,254RGDNCBI36
Celera6133,016,564 - 133,016,693RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,844,891 - 129,845,020UniSTS
GeneMap99-GB4 RH Map6532.92UniSTS
NCBI RH Map61538.9UniSTS
SHGC-12753  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,269,561 - 132,269,899UniSTSGRCh37
Build 366132,311,254 - 132,311,592RGDNCBI36
Celera6133,016,693 - 133,017,029RGD
Cytogenetic Map6q23.1UniSTS
HuRef6129,845,020 - 129,845,356UniSTS
Stanford-G3 RH Map65370.0UniSTS
NCBI RH Map61528.8UniSTS
GeneMap99-G3 RH Map65673.0UniSTS
stSG626375  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,268,980 - 132,270,285UniSTSGRCh37
Build 366132,310,673 - 132,311,978RGDNCBI36
Celera6133,016,112 - 133,017,415RGD
HuRef6129,844,439 - 129,845,742UniSTS
stSG626376  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh376132,270,447 - 132,271,696UniSTSGRCh37
Build 366132,312,140 - 132,313,389RGDNCBI36
Celera6133,017,577 - 133,018,825RGD
HuRef6129,845,904 - 129,847,152UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2438 2788 2243 4974 1723 2340 6 624 1448 465 2270 6813 5979 52 3730 1 852 1742 1606 174 1

Sequence