GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | CCN2 | multiple interactions | ISO | Ccn2 (Mus musculus) | 6480464 | CTD | [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA; [Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 protein; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of and results in increased expression of CCN2; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CCN2 gene; [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of CCN2 mRNA; [Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA; CCL2 protein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA]; olaparib inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA]; Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of CCN2 mRNA]; Rosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 mRNA]; Rosiglitazone inhibits the reaction [[Dietary Fats co-treated with Choline deficiency co-treated with Methionine deficiency] results in increased expression of CCN2 protein] | PMID:18991162 PMID:20697377 PMID:20938992 PMID:22915297 PMID:27984176 | | ||||||||||||||||||||||
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