MIR18A (microRNA 18a) - Rat Genome Database
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Gene: MIR18A (microRNA 18a) Homo sapiens
Analyze
Symbol: MIR18A
Name: microRNA 18a
RGD ID: 1350945
HGNC Page HGNC
Description: Predicted to be involved in several processes, including animal organ development; cellular response to estrogen stimulus; and regulation of gene expression. Predicted to localize to axon. Biomarker of hepatocellular carcinoma.
Type: ncrna
RefSeq Status: PROVISIONAL
Also known as: C13orf25; hsa-mir-18; hsa-mir-18a; microrna 18; miR-18; mir-18a; MIR17HG; MIR18; MIRH1; MIRHG1; MIRN18; MIRN18A; miRNA18A
RGD Orthologs
Mouse
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1391,350,751 - 91,350,821 (+)EnsemblGRCh38hg38GRCh38
GRCh381391,350,751 - 91,350,821 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371392,003,005 - 92,003,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,005 - 90,801,075 (+)NCBINCBI36hg18NCBI36
Celera1372,849,976 - 72,850,046 (+)NCBI
Cytogenetic Map13q31.3NCBI
HuRef1372,598,840 - 72,598,910 (+)NCBIHuRef
CHM1_11391,971,645 - 91,971,715 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
axon  (ISO)

References

Additional References at PubMed
PMID:11679670   PMID:11914277   PMID:15126345   PMID:15325244   PMID:15978578   PMID:16381832   PMID:17558416   PMID:17604727   PMID:17616659   PMID:18632605   PMID:18766170   PMID:19203451  
PMID:19233176   PMID:19372139   PMID:19684618   PMID:20299512   PMID:20940405   PMID:21037258   PMID:21067317   PMID:21145484   PMID:21501375   PMID:21627027   PMID:21935572   PMID:21953462  
PMID:21980462   PMID:22045190   PMID:23097559   PMID:23229340   PMID:23280137   PMID:23322197   PMID:23437304   PMID:23579215   PMID:23673725   PMID:23857602   PMID:24166503   PMID:24169826  
PMID:24184144   PMID:24360091   PMID:24624454   PMID:24626859   PMID:24633304   PMID:24657544   PMID:24664294   PMID:25069832   PMID:25233396   PMID:25379703   PMID:25452107   PMID:25755757  
PMID:25955393   PMID:25963391   PMID:26044722   PMID:26173586   PMID:26398009   PMID:26646931   PMID:26672767   PMID:26683099   PMID:26772615   PMID:26783726   PMID:27198161   PMID:27291152  
PMID:27390086   PMID:27412935   PMID:27421245   PMID:27473081   PMID:27789587   PMID:28213378   PMID:28399983   PMID:28431233   PMID:28471447   PMID:28481041   PMID:28607111   PMID:28661068  
PMID:28733035   PMID:28766230   PMID:28871004   PMID:28871951   PMID:29068867   PMID:29266846   PMID:29408336   PMID:29422114   PMID:29465000   PMID:29693135   PMID:29748618   PMID:29860718  
PMID:29946118   PMID:29988076   PMID:30055570   PMID:30078184   PMID:30146846   PMID:30216788   PMID:30257388   PMID:30259640   PMID:30308669   PMID:30365458   PMID:30481787   PMID:30536700  
PMID:30569153   PMID:30594162   PMID:30957284   PMID:31115881   PMID:31257489   PMID:31262449   PMID:31352515   PMID:31473323   PMID:31659158   PMID:32370743   PMID:32382575   PMID:32458821  
PMID:32538667   PMID:32555725   PMID:32862588   PMID:33175907  


Genomics

Comparative Map Data
MIR18A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1391,350,751 - 91,350,821 (+)EnsemblGRCh38hg38GRCh38
GRCh381391,350,751 - 91,350,821 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371392,003,005 - 92,003,075 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361390,801,005 - 90,801,075 (+)NCBINCBI36hg18NCBI36
Celera1372,849,976 - 72,850,046 (+)NCBI
Cytogenetic Map13q31.3NCBI
HuRef1372,598,840 - 72,598,910 (+)NCBIHuRef
CHM1_11391,971,645 - 91,971,715 (+)NCBICHM1_1
Mir18
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3914115,281,283 - 115,281,378 (+)NCBIGRCm39mm39
GRCm39 Ensembl14115,281,283 - 115,281,378 (+)Ensembl
GRCm3814115,043,851 - 115,043,946 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl14115,043,851 - 115,043,946 (+)EnsemblGRCm38mm10GRCm38
MGSCv3714115,443,073 - 115,443,168 (+)NCBIGRCm37mm9NCBIm37
Celera14113,634,419 - 113,634,514 (+)NCBICelera
Cytogenetic Map14E4NCBI
Mir18a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21592,180,765 - 92,180,860 (+)NCBI
Rnor_6.0 Ensembl15100,180,015 - 100,180,110 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.015100,180,015 - 100,180,110 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.015103,641,038 - 103,641,133 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1591,045,445 - 91,045,540 (+)NCBICelera
Cytogenetic Map15q23NCBI
MIR18A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2242,478,138 - 42,478,229 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12242,478,138 - 42,478,229 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
MIR18A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1160,734,791 - 60,734,882 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11160,734,791 - 60,734,882 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21166,610,195 - 66,610,286 (+)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Confirmed Targets
Gene TargetMature miRNAMethod NameResult TypeData TypeSupport TypePMID
ESR1hsa-miR-18a-5pMirtarbaseexternal_infoWestern blot//qRT-PCR//Luciferase reporter assayFunctional MTI19706389
ESR1hsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//MicroarrayFunctional MTI19684618
ESR1hsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI20080637
IGF2BP2hsa-miR-18a-5pMirtarbaseexternal_infoMicroarray//Northern blotFunctional MTI (Weak)16331254
PTENhsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotNon-Functional MTI20008935
CCN2hsa-miR-18a-5pMirtarbaseexternal_infoWestern blot//Microarray//Northern blot//LuciferasFunctional MTI16331254
CCN2hsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI19233176
NCOA3hsa-miR-18a-5pMirtarbaseexternal_infoWestern blotNon-Functional MTI19706389
TNFSF11hsa-miR-18a-5pMirtarbaseexternal_infoMicroarray//Northern blot//Luciferase reporter assFunctional MTI16331254
NR3C1hsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//Western blot//pMIR-REPOFunctional MTI19131573
TSC22D3hsa-miR-18a-5pMirtarbaseexternal_infoqRT-PCRFunctional MTI (Weak)19131573
HIF1Ahsa-miR-18a-5pMirtarbaseexternal_infoSequencingFunctional MTI (Weak)20371350
TGFBR2hsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assay//MicroarrayNon-Functional MTI20940405
PRMT5hsa-miR-18a-5pMirtarbaseexternal_infoimmunohistochemistry//Microarray//qRT-PCR//WesternFunctional MTI19167416
SMAD4hsa-miR-18a-5pMirtarbaseexternal_infoImmunoblot//Luciferase reporter assay//Microarray/Functional MTI20940405
HSF2hsa-miR-18a-5pMirtarbaseexternal_infoImmunofluorescence//In situ hybridization//LuciferFunctional MTI20724452
ATMhsa-miR-18a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23437304
DICER1hsa-miR-18a-5pMirtarbaseexternal_infoImmunohistochemistry//In situ hybridization//LucifFunctional MTI23097559
SMAD3hsa-miR-18a-5pMirtarbaseexternal_infoWestern blotFunctional MTI23249750
POGKhsa-miR-18a-5pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
XYLT2hsa-miR-18a-5pTarbaseexternal_infoSequencingPOSITIVE
ATMhsa-miR-18a-5pOncomiRDBexternal_infoNANA23437304
DICER1hsa-miR-18a-5pOncomiRDBexternal_infoNANA23097559
CDK19hsa-miR-18a-5pOncomiRDBexternal_infoNANA22308110
ATMhsa-miR-18a-5pOncomiRDBexternal_infoNANA21980462
DICER1hsa-miR-18a-5pOncomiRDBexternal_infoNANA21935572
THBS1hsa-miR-18a-5pOncomiRDBexternal_infoNANA21402698
ESR1hsa-miR-18a-5pOncomiRDBexternal_infoNANA20080637
ESR1hsa-miR-18a-5pOncomiRDBexternal_infoNANA19684618
ESR1hsa-miR-18a-5pOncomiRDBexternal_infoNANA19027010
KRAShsa-miR-18a-3pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI19372139
ACSM2Ahsa-miR-18a-3pMirtarbaseexternal_infoCLASHFunctional MTI (Weak)23622248
CCN2hsa-miR-18a-3pMirecordsexternal_info{changed}NA20305691
THBS1hsa-miR-18a-3pMirecordsexternal_infoNANA20299512
ESR1hsa-miR-18a-3pMirecordsexternal_infoNANA20080637
KRAShsa-miR-18a-3pOncomiRDBexternal_infoNANA19372139

Predicted Targets
Summary Value
Count of predictions:62993
Count of gene targets:19488
Count of transcripts:47920
Interacting mature miRNAs:hsa-miR-18a-3p, hsa-miR-18a-5p
Prediction methods:Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENST00000362310
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1391,350,751 - 91,350,821 (+)Ensembl
RefSeq Acc Id: NR_029488
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381391,350,751 - 91,350,821 (+)NCBI
GRCh371392,003,005 - 92,003,075 (+)RGD
Celera1372,849,976 - 72,850,046 (+)RGD
HuRef1372,598,840 - 72,598,910 (+)ENTREZGENE
CHM1_11391,971,645 - 91,971,715 (+)NCBI
Sequence:

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 13q14.12-31.3(chr13:44967523-92738168)x1 copy number loss See cases [RCV000050891] Chr13:44967523..92738168 [GRCh38]
Chr13:45541658..93390421 [GRCh37]
Chr13:44439658..92188422 [NCBI36]
Chr13:13q14.12-31.3		 pathogenic
GRCh38/hg38 13q22.3-32.1(chr13:78349126-94701844)x1 copy number loss See cases [RCV000051379] Chr13:78349126..94701844 [GRCh38]
Chr13:78923261..95354098 [GRCh37]
Chr13:77821262..94152099 [NCBI36]
Chr13:13q22.3-32.1		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:82581008-114327173)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051380]|See cases [RCV000051380] Chr13:82581008..114327173 [GRCh38]
Chr13:83155143..115085141 [GRCh37]
Chr13:82053144..114110750 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-32.1(chr13:83947821-95128969)x1 copy number loss See cases [RCV000051414] Chr13:83947821..95128969 [GRCh38]
Chr13:84521956..95781223 [GRCh37]
Chr13:83419957..94579224 [NCBI36]
Chr13:13q31.1-32.1		 pathogenic
GRCh38/hg38 13q31.2-32.1(chr13:88260962-97285754)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051415]|See cases [RCV000051415] Chr13:88260962..97285754 [GRCh38]
Chr13:88913217..97938008 [GRCh37]
Chr13:87711218..96736009 [NCBI36]
Chr13:13q31.2-32.1		 pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:88323009-98888644)x1 copy number loss See cases [RCV000051416] Chr13:88323009..98888644 [GRCh38]
Chr13:88975264..99540898 [GRCh37]
Chr13:87773265..98338899 [NCBI36]
Chr13:13q31.2-32.3		 pathogenic
GRCh38/hg38 13q31.3-32.1(chr13:89549510-96657834)x1 copy number loss See cases [RCV000051417] Chr13:89549510..96657834 [GRCh38]
Chr13:90201764..97310088 [GRCh37]
Chr13:88999765..96108089 [NCBI36]
Chr13:13q31.3-32.1		 pathogenic
GRCh38/hg38 13q31.1-33.2(chr13:82032938-106082542)x3 copy number gain See cases [RCV000051179] Chr13:82032938..106082542 [GRCh38]
Chr13:82607073..106734891 [GRCh37]
Chr13:81505074..105532892 [NCBI36]
Chr13:13q31.1-33.2		 pathogenic
GRCh38/hg38 13q31.3(chr13:90215412-91366486)x1 copy number loss See cases [RCV000051921] Chr13:90215412..91366486 [GRCh38]
Chr13:90867666..92018740 [GRCh37]
Chr13:89665667..90816741 [NCBI36]
Chr13:13q31.3		 uncertain significance
GRCh38/hg38 13q31.3(chr13:90973752-93097331)x1 copy number loss See cases [RCV000051922] Chr13:90973752..93097331 [GRCh38]
Chr13:91626006..93749584 [GRCh37]
Chr13:90424007..92547585 [NCBI36]
Chr13:13q31.3		 uncertain significance
GRCh38/hg38 13q12.11-34(chr13:18946182-114304628)x3 copy number gain See cases [RCV000053726] Chr13:18946182..114304628 [GRCh38]
Chr13:19520322..115070103 [GRCh37]
Chr13:18418322..114088205 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000053731] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18565048-114327173)x3 copy number gain See cases [RCV000053719] Chr13:18565048..114327173 [GRCh38]
Chr13:19139188..115085141 [GRCh37]
Chr13:18037188..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18850545-114327173)x3 copy number gain See cases [RCV000053723] Chr13:18850545..114327173 [GRCh38]
Chr13:19296527..115085141 [GRCh37]
Chr13:18194527..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q13.2-34(chr13:33528097-114327173)x3 copy number gain See cases [RCV000053759] Chr13:33528097..114327173 [GRCh38]
Chr13:34102234..115085141 [GRCh37]
Chr13:33000234..114110750 [NCBI36]
Chr13:13q13.2-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:43219125-114327314)x3 copy number gain See cases [RCV000053762] Chr13:43219125..114327314 [GRCh38]
Chr13:43793261..115085141 [GRCh37]
Chr13:42691261..114110891 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.11-34(chr13:44164751-114327173)x3 copy number gain See cases [RCV000053764] Chr13:44164751..114327173 [GRCh38]
Chr13:44738887..115085141 [GRCh37]
Chr13:43636887..114110750 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q14.12-34(chr13:44733046-114327173)x3 copy number gain See cases [RCV000053767] Chr13:44733046..114327173 [GRCh38]
Chr13:45307182..115085141 [GRCh37]
Chr13:44205182..114110750 [NCBI36]
Chr13:13q14.12-34		 pathogenic
GRCh38/hg38 13q22.1-34(chr13:74345951-114327314)x3 copy number gain See cases [RCV000053770] Chr13:74345951..114327314 [GRCh38]
Chr13:74920088..115085141 [GRCh37]
Chr13:73818089..114110891 [NCBI36]
Chr13:13q22.1-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:80628584-114327173)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053772]|See cases [RCV000053772] Chr13:80628584..114327173 [GRCh38]
Chr13:81202719..115085141 [GRCh37]
Chr13:80100720..114110750 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q31.3(chr13:90644219-92557099)x1 copy number loss See cases [RCV000234861] Chr13:90644219..92557099 [GRCh37]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114298614)x3 copy number gain See cases [RCV000134104] Chr13:19833130..114298614 [GRCh38]
Chr13:20407270..115064089 [GRCh37]
Chr13:19305270..114082191 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q11-34(chr13:18445862-114327173)x1 copy number loss See cases [RCV000135610] Chr13:18445862..114327173 [GRCh38]
Chr13:19020001..115085141 [GRCh37]
Chr13:10098739..114110750 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q22.3-31.3(chr13:77061780-92460406)x1 copy number loss See cases [RCV000136886] Chr13:77061780..92460406 [GRCh38]
Chr13:77635915..93112659 [GRCh37]
Chr13:76533916..91910660 [NCBI36]
Chr13:13q22.3-31.3		 pathogenic
GRCh38/hg38 13q31.2-34(chr13:88937651-114327173)x3 copy number gain See cases [RCV000137102] Chr13:88937651..114327173 [GRCh38]
Chr13:89589905..115085141 [GRCh37]
Chr13:88387906..114110750 [NCBI36]
Chr13:13q31.2-34		 pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84005264-92784013)x1 copy number loss See cases [RCV000137272] Chr13:84005264..92784013 [GRCh38]
Chr13:84579399..93436266 [GRCh37]
Chr13:83477400..92234267 [NCBI36]
Chr13:13q31.1-31.3		 likely pathogenic
GRCh38/hg38 13q14.11-34(chr13:40942298-114340331)x1 copy number loss See cases [RCV000137893] Chr13:40942298..114340331 [GRCh38]
Chr13:41516434..115085141 [GRCh37]
Chr13:40414434..114123908 [NCBI36]
Chr13:13q14.11-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:78999318-114327106)x3 copy number gain See cases [RCV000138742] Chr13:78999318..114327106 [GRCh38]
Chr13:79573453..115085141 [GRCh37]
Chr13:78471454..114110683 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:86788927-114340331)x1 copy number loss See cases [RCV000138340] Chr13:86788927..114340331 [GRCh38]
Chr13:87441182..115085141 [GRCh37]
Chr13:86239183..114123908 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19833130-114327106)x3 copy number gain See cases [RCV000139078] Chr13:19833130..114327106 [GRCh38]
Chr13:20407270..115085141 [GRCh37]
Chr13:19305270..114110683 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q31.2-32.3(chr13:87944479-99866542)x1 copy number loss See cases [RCV000139047] Chr13:87944479..99866542 [GRCh38]
Chr13:88596734..100518796 [GRCh37]
Chr13:87394735..99316797 [NCBI36]
Chr13:13q31.2-32.3		 pathogenic
GRCh38/hg38 13q11-34(chr13:18456040-114340285)x3 copy number gain See cases [RCV000140004] Chr13:18456040..114340285 [GRCh38]
Chr13:19030180..115105760 [GRCh37]
Chr13:17928180..114123862 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q31.1-34(chr13:78964223-114340331)x3 copy number gain See cases [RCV000141248] Chr13:78964223..114340331 [GRCh38]
Chr13:79538358..115085141 [GRCh37]
Chr13:78436359..114123908 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q31.1-31.3(chr13:84052824-91838339)x3 copy number gain See cases [RCV000141994] Chr13:84052824..91838339 [GRCh38]
Chr13:84626959..92490593 [GRCh37]
Chr13:83524960..91288594 [NCBI36]
Chr13:13q31.1-31.3		 uncertain significance
GRCh38/hg38 13q31.1-34(chr13:83288131-114342258)x3 copy number gain See cases [RCV000141804] Chr13:83288131..114342258 [GRCh38]
Chr13:83862266..115107733 [GRCh37]
Chr13:82760267..114125835 [NCBI36]
Chr13:13q31.1-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19671934-114340331)x3 copy number gain See cases [RCV000142924] Chr13:19671934..114340331 [GRCh38]
Chr13:20246074..115085141 [GRCh37]
Chr13:19144074..114123908 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh38/hg38 13q31.3(chr13:91283077-91394459)x1 copy number loss See cases [RCV000143094] Chr13:91283077..91394459 [GRCh38]
Chr13:91935331..92046713 [GRCh37]
Chr13:90733332..90844714 [NCBI36]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q31.3(chr13:91282882-91394459)x1 copy number loss See cases [RCV000143162] Chr13:91282882..91394459 [GRCh38]
Chr13:91935136..92046713 [GRCh37]
Chr13:90733137..90844714 [NCBI36]
Chr13:13q31.3		 pathogenic
GRCh38/hg38 13q11-34(chr13:18862146-114342258)x3 copy number gain See cases [RCV000143462] Chr13:18862146..114342258 [GRCh38]
Chr13:19436286..115107733 [GRCh37]
Chr13:18334286..114125835 [NCBI36]
Chr13:13q11-34		 pathogenic
GRCh38/hg38 13q12.11-34(chr13:19837395-114327173)x3 copy number gain See cases [RCV000148126] Chr13:19837395..114327173 [GRCh38]
Chr13:20411535..115085141 [GRCh37]
Chr13:19309535..114110750 [NCBI36]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:89796110-115083342)x1 copy number loss See cases [RCV000240161] Chr13:89796110..115083342 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092569)x3 copy number gain See cases [RCV000240150] Chr13:19571503..115092569 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.3(chr13:91209639-94704856)x3 copy number gain See cases [RCV000240035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3		 uncertain significance
GRCh37/hg19 13q22.1-31.3(chr13:74459395-93481294)x1 copy number loss See cases [RCV000598789] Chr13:74459395..93481294 [GRCh37]
Chr13:13q22.1-31.3		 pathogenic
GRCh37/hg19 13q14.3-33.3(chr13:53551300-109850651)x1 copy number loss See cases [RCV000449272] Chr13:53551300..109850651 [GRCh37]
Chr13:13q14.3-33.3		 pathogenic
GRCh37/hg19 13q21.2-34(chr13:61424168-115107733)x3 copy number gain See cases [RCV000449118] Chr13:61424168..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q12.11-34(chr13:19571503-115092510) copy number gain See cases [RCV000449142] Chr13:19571503..115092510 [GRCh37]
Chr13:13q12.11-34		 pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:86963003-93390362)x3 copy number gain See cases [RCV000446248] Chr13:86963003..93390362 [GRCh37]
Chr13:13q31.1-31.3		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:82221361-115092569)x3 copy number gain See cases [RCV000447429] Chr13:82221361..115092569 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q21.1-34(chr13:56431743-115107733) copy number gain See cases [RCV000510722] Chr13:56431743..115107733 [GRCh37]
Chr13:13q21.1-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain See cases [RCV000445886] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-33.1(chr13:81851091-102864674)x1 copy number loss See cases [RCV000448988] Chr13:81851091..102864674 [GRCh37]
Chr13:13q31.1-33.1		 pathogenic
GRCh37/hg19 13q31.2-34(chr13:88073140-115107733)x1 copy number loss See cases [RCV000448405] Chr13:88073140..115107733 [GRCh37]
Chr13:13q31.2-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733) copy number gain See cases [RCV000510405] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.33-34(chr13:71871468-115107733)x4 copy number gain See cases [RCV000510281] Chr13:71871468..115107733 [GRCh37]
Chr13:13q21.33-34		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:80058840-115107733)x3 copy number gain See cases [RCV000510566] Chr13:80058840..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436287-115107733)x3 copy number gain See cases [RCV000511880] Chr13:19436287..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-33.3(chr13:80572498-108719528)x1 copy number loss See cases [RCV000510890] Chr13:80572498..108719528 [GRCh37]
Chr13:13q31.1-33.3		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:83435292-115107733)x3 copy number gain See cases [RCV000512605] Chr13:83435292..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
GRCh37/hg19 13q14.3-32.1(chr13:53932358-96586363)x3 copy number gain See cases [RCV000512571] Chr13:53932358..96586363 [GRCh37]
Chr13:13q14.3-32.1		 pathogenic
GRCh37/hg19 13q31.1-34(chr13:85176519-115107733)x3 copy number gain See cases [RCV000512242] Chr13:85176519..115107733 [GRCh37]
Chr13:13q31.1-34		 pathogenic
Single allele duplication not provided [RCV000678035] Chr13:91209639..94704856 [GRCh37]
Chr13:13q31.3		 likely pathogenic
GRCh37/hg19 13q22.3-34(chr13:78590089-115107733)x3 copy number gain not provided [RCV000683571] Chr13:78590089..115107733 [GRCh37]
Chr13:13q22.3-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19058717-115103529)x3 copy number gain not provided [RCV000738115] Chr13:19058717..115103529 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q31.1-31.3(chr13:85005334-92461147)x1 copy number loss not provided [RCV000738268] Chr13:85005334..92461147 [GRCh37]
Chr13:13q31.1-31.3		 pathogenic
GRCh37/hg19 13q11-34(chr13:19031237-115107157)x3 copy number gain not provided [RCV000750643] Chr13:19031237..115107157 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q21.1-31.3(chr13:57058434-94684615)x1 copy number loss not provided [RCV000750731] Chr13:57058434..94684615 [GRCh37]
Chr13:13q21.1-31.3		 pathogenic
GRCh37/hg19 13q31.3(chr13:91460305-92069153)x3 copy number gain not provided [RCV001006582] Chr13:91460305..92069153 [GRCh37]
Chr13:13q31.3		 likely pathogenic
GRCh37/hg19 13q21.2-34(chr13:61775567-115107733)x3 copy number gain not provided [RCV000848025] Chr13:61775567..115107733 [GRCh37]
Chr13:13q21.2-34		 pathogenic
GRCh37/hg19 13q11-34(chr13:19436286-115107733)x3 copy number gain not provided [RCV000849129] Chr13:19436286..115107733 [GRCh37]
Chr13:13q11-34		 pathogenic
GRCh37/hg19 13q14.3-34(chr13:53262013-115107733)x1 copy number loss not provided [RCV001006567] Chr13:53262013..115107733 [GRCh37]
Chr13:13q14.3-34		 pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:31548 AgrOrtholog
COSMIC MIR18A COSMIC
Ensembl Genes ENSG00000283815 Ensembl, ENTREZGENE
Ensembl Transcript ENST00000362310 ENTREZGENE
GTEx ENSG00000283815 GTEx
HGNC ID HGNC:31548 ENTREZGENE
Human Proteome Map MIR18A Human Proteome Map
miRBase MI0000072 ENTREZGENE
NCBI Gene 406953 ENTREZGENE
OMIM 609417 OMIM
PharmGKB PA164722537 PharmGKB
RNAcentral URS000035CC3E RNACentral
  URS00003B0CDB RNACentral
  URS00004131FE RNACentral