EGFR (epidermal growth factor receptor) - Rat Genome Database

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Gene: EGFR (epidermal growth factor receptor) Homo sapiens
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Symbol: EGFR
Name: epidermal growth factor receptor
RGD ID: 69152
HGNC Page HGNC
Description: Exhibits several functions, including actin filament binding activity; enzyme binding activity; and epidermal growth factor-activated receptor activity. Contributes to nitric-oxide synthase regulator activity. Involved in several processes, including positive regulation of cellular metabolic process; regulation of intracellular signal transduction; and regulation of protein metabolic process. Localizes to several cellular components, including basolateral plasma membrane; endosome; and membrane raft. Implicated in several diseases, including breast carcinoma; colorectal cancer; lung disease (multiple); pancreatic cancer; and prostate cancer. Biomarker of several diseases, including Human papillomavirus infectious disease; breast cancer (multiple); carcinoma (multiple); chronic obstructive pulmonary disease; and pulmonary hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian); epidermal growth factor receptor tyrosine kinase domain; erb-b2 receptor tyrosine kinase 1; ERBB; ERBB1; ERRP; erythroblastic leukemia viral (v-erb-b) oncogene homolog; HER1; mENA; NISBD2; PIG61; proto-oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl755,019,017 - 55,211,628 (+)EnsemblGRCh38hg38GRCh38
GRCh38755,019,017 - 55,211,628 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37755,086,710 - 55,279,321 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36755,054,219 - 55,242,525 (+)NCBINCBI36hg18NCBI36
Build 34754,860,933 - 55,012,947NCBI
Celera755,192,332 - 55,380,657 (+)NCBI
Cytogenetic Map7p11.2NCBI
HuRef754,924,934 - 55,112,834 (+)NCBIHuRef
CHM1_1755,089,165 - 55,277,398 (+)NCBICHM1_1
CRA_TCAGchr7v2755,092,507 - 55,280,831 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model