(+)-pilocarpine decreases expression ISO RGD:2543 6480464 Pilocarpine results in decreased expression of EGFR mRNA CTD PMID:17971868 (+)-Tetrandrine decreases phosphorylation EXP 6480464 tetrandrine results in decreased phosphorylation of EGFR protein CTD PMID:30549224 (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA more ... CTD PMID:17616711 more ... (-)-epigallocatechin 3-gallate multiple interactions ISO RGD:10511 6480464 epigallocatechin gallate inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 (-)-epigallocatechin 3-gallate increases expression EXP 6480464 epigallocatechin gallate results in increased expression of EGFR mRNA CTD PMID:22079256 (20S)-ginsenoside Rg3 affects phosphorylation EXP 6480464 ginsenoside Rg3 affects the phosphorylation of EGFR protein CTD PMID:25824408 (20S)-ginsenoside Rg3 multiple interactions EXP 6480464 EGF protein promotes the reaction [ginsenoside Rg3 affects the phosphorylation of EGFR protein] more ... CTD PMID:25824408 (R)-mevalonic acid multiple interactions ISO RGD:2543 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]] CTD PMID:20359552 (R)-noradrenaline multiple interactions ISO RGD:2543 6480464 EGFR protein inhibits the reaction [Norepinephrine results in increased phosphorylation of SHC1 protein alternative form] CTD PMID:19168439 (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:25866363 (S)-nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 (S)-nicotine multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 (S)-nicotine decreases expression ISO RGD:2543 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane multiple interactions ISO RGD:2543 6480464 2 more ... CTD PMID:19414516 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane increases phosphorylation EXP 6480464 2 more ... CTD PMID:28426875 1,2,3,4,7,8-Hexachlorodibenzofuran decreases activity ISO RGD:10511 6480464 1 more ... CTD PMID:2718174 1,2-dichloroethane decreases expression ISO RGD:10511 6480464 ethylene dichloride results in decreased expression of EGFR mRNA CTD PMID:28189721 , PMID:28960355 1,2-Naphthoquinone multiple interactions EXP 6480464 1, 2-naphthoquinone results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:24067727 1-octadec-9-enoylglycero-3-phosphate increases phosphorylation EXP 6480464 lysophosphatidic acid results in increased phosphorylation of EGFR protein CTD PMID:23127547 1-octadec-9-enoylglycero-3-phosphate multiple interactions EXP 6480464 GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] more ... CTD PMID:23127547 16,16-dimethylprostaglandin E2 multiple interactions ISO RGD:10511 6480464 EGFR affects the reaction [16, 16-Dimethylprostaglandin E2 results in increased phosphorylation of AKT1 protein] CTD PMID:15578100 17alpha-ethynylestradiol increases expression ISO RGD:10511 6480464 Ethinyl Estradiol results in increased expression of EGFR mRNA CTD PMID:17942748 17alpha-ethynylestradiol increases expression ISO RGD:2543 6480464 Ethinyl Estradiol results in increased expression of EGFR protein CTD PMID:2197011 , PMID:2786453 17alpha-ethynylestradiol increases stability ISO RGD:2543 6480464 Ethinyl Estradiol results in increased stability of EGFR protein CTD PMID:2197011 17alpha-ethynylestradiol affects expression ISO RGD:10511 6480464 Ethinyl Estradiol affects the expression of EGFR mRNA CTD PMID:17555576 17beta-estradiol multiple interactions ISO RGD:10511 6480464 ESR1 protein promotes the reaction [Estradiol results in increased expression of EGFR mRNA] more ... CTD PMID:22414604 , PMID:25210133 17beta-estradiol increases activity EXP 6480464 Estradiol results in increased activity of EGFR protein CTD PMID:15802018 17beta-estradiol increases phosphorylation EXP 6480464 Estradiol results in increased phosphorylation of EGFR protein CTD PMID:20005069 more ... 17beta-estradiol decreases expression ISO RGD:2543 6480464 Estradiol results in decreased expression of EGFR mRNA CTD PMID:20068009 , PMID:31119341 17beta-estradiol multiple interactions ISO RGD:2543 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein] CTD PMID:8888411 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:19619570 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of EGFR mRNA, Estradiol results in decreased expression of EGFR protein CTD PMID:20005069 17beta-estradiol multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:17622325 more ... 17beta-estradiol increases expression ISO RGD:2543 6480464 Estradiol results in increased expression of EGFR protein CTD PMID:8888411 17beta-estradiol increases expression ISO RGD:10511 6480464 Estradiol results in increased expression of EGFR mRNA CTD PMID:25210133 17beta-estradiol 17-glucosiduronic acid multiple interactions ISO RGD:2543 6480464 EGFR protein promotes the reaction [estradiol-17 beta-glucuronide affects the localization of and results in decreased activity of ABCC2 protein] more ... CTD PMID:25813982 17beta-estradiol 3-benzoate increases expression ISO RGD:2543 6480464 estradiol 3-benzoate results in increased expression of EGFR protein CTD PMID:15778002 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:2543 6480464 Metribolone results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:17272394 17beta-hydroxy-5alpha-androstan-3-one increases expression EXP 6480464 Dihydrotestosterone results in increased expression of EGFR mRNA CTD PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl affects localization EXP 6480464 2 more ... CTD PMID:19632255 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions EXP 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl affects binding EXP 6480464 2 more ... CTD PMID:29329451 2,2',4,4',5,5'-hexachlorobiphenyl increases phosphorylation EXP 6480464 2 more ... CTD PMID:19632255 2,2',4,4'-Tetrabromodiphenyl ether affects expression ISO RGD:10511 6480464 2 more ... CTD PMID:30294300 2,3,4,7,8-Pentachlorodibenzofuran decreases activity ISO RGD:10511 6480464 2 more ... CTD PMID:2718174 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR mRNA more ... CTD PMID:11309286 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA CTD PMID:14708085 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:21570461 , PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10511 6480464 CSK protein promotes the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] more ... CTD PMID:6309801 , PMID:9664232 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:2543 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:10401681 , PMID:15592923 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR CTD PMID:1336723 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation EXP 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EGFR protein CTD PMID:20971882 , PMID:26971374 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:2543 6480464 Tetrachlorodibenzodioxin affects the expression of EGFR mRNA CTD PMID:22298810 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:19619570 more ... 2,3,7,8-tetrachlorodibenzodioxine affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Tetrachlorodibenzodioxin CTD PMID:9163677 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10511 6480464 Tetrachlorodibenzodioxin results in increased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in increased expression of EGFR protein CTD PMID:17942748 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2543 6480464 Tetrachlorodibenzodioxin results in decreased expression of EGFR mRNA, Tetrachlorodibenzodioxin results in decreased expression of EGFR protein CTD PMID:20959002 , PMID:8403215 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:2543 6480464 [Diethylnitrosamine co-treated with Tetrachlorodibenzodioxin] results in decreased expression of EGFR protein more ... CTD PMID:11752688 more ... 2,5-hexanedione increases expression ISO RGD:2543 6480464 2, 5-hexanedione results in increased expression of EGFR mRNA CTD PMID:16141653 2-acetamidofluorene multiple interactions ISO RGD:2543 6480464 2-Acetylaminofluorene affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:10900465 2-acetamidofluorene decreases expression ISO RGD:2543 6480464 2-Acetylaminofluorene results in decreased expression of EGFR mRNA CTD PMID:22213190 2-deoxy-D-glucose multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 2-deoxy-D-glucose increases import EXP 6480464 EGFR protein mutant form results in increased import of Deoxyglucose CTD PMID:19625624 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 2-nitrotoluene decreases expression ISO RGD:10511 6480464 2-nitrotoluene results in decreased expression of EGFR mRNA CTD PMID:15618236 3',5'-cyclic AMP multiple interactions ISO RGD:10511 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 3,3',4,4',5-pentachlorobiphenyl affects binding EXP 6480464 3 more ... CTD PMID:29329451 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:29329451 3,3',5,5'-tetrabromobisphenol A increases phosphorylation EXP 6480464 tetrabromobisphenol A results in increased phosphorylation of EGFR protein CTD PMID:26718265 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein], bisindolylmaleimide I inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 3-chloropropane-1,2-diol increases expression ISO RGD:2543 6480464 alpha-Chlorohydrin results in increased expression of EGFR mRNA CTD PMID:28522335 3-methylcholanthrene decreases expression ISO RGD:2543 6480464 Methylcholanthrene results in decreased expression of EGFR mRNA CTD PMID:29094188 3H-1,2-dithiole-3-thione decreases expression ISO RGD:2543 6480464 1, 2-dithiol-3-thione results in decreased expression of EGFR mRNA CTD PMID:19162173 4'-epidoxorubicin multiple interactions EXP 6480464 EGFR protein affects the susceptibility to [Epirubicin co-treated with CMF regimen] CTD PMID:18768436 4,4'-diaminodiphenylmethane increases expression ISO RGD:10511 6480464 4, 4'-diaminodiphenylmethane results in increased expression of EGFR mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol increases expression ISO RGD:10511 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of EGFR mRNA CTD PMID:30951980 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases phosphorylation EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein CTD PMID:16671086 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions EXP 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 4-hydroxyphenyl retinamide decreases expression ISO RGD:10511 6480464 Fenretinide results in decreased expression of EGFR mRNA CTD PMID:28973697 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of EGFR mRNA CTD PMID:16570282 4-nitrotoluene decreases expression ISO RGD:10511 6480464 4-nitrotoluene results in decreased expression of EGFR protein CTD PMID:15618236 4-tert-Octylphenol increases expression ISO RGD:2543 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 4-vinylcyclohexene dioxide affects expression ISO RGD:10511 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of EGFR mRNA CTD PMID:20829426 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases phosphorylation ISO RGD:2543 6480464 cholesterol alpha-oxide results in increased phosphorylation of EGFR protein CTD PMID:20466046 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of EGFR mRNA CTD PMID:19151715 5-chloro-7-iodoquinolin-8-ol multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 5-fluorouracil decreases response to substance EXP 6480464 EGFR gene polymorphism results in decreased susceptibility to Fluorouracil CTD PMID:19217205 5-fluorouracil decreases expression EXP 6480464 Fluorouracil results in decreased expression of EGFR protein CTD PMID:17918158 , PMID:17982676 5-fluorouracil increases phosphorylation EXP 6480464 Fluorouracil results in increased phosphorylation of EGFR protein CTD PMID:18794807 5-fluorouracil affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Fluorouracil CTD PMID:16836928 , PMID:17169374 5-fluorouracil multiple interactions EXP 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... 6-(4-chlorophenyl)imidazo[2,1-b][1,3]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime multiple interactions EXP 6480464 6-(4-chlorophenyl)imidazo(2 more ... CTD PMID:25625231 , PMID:30364229 6-chrysenamine multiple interactions ISO RGD:10511 6480464 6-chrysenamine inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 6-propyl-2-thiouracil increases expression ISO RGD:2543 6480464 Propylthiouracil results in increased expression of EGFR mRNA CTD PMID:24780913 7-ketocholesterol increases phosphorylation ISO RGD:2543 6480464 7-ketocholesterol results in increased phosphorylation of EGFR protein CTD PMID:20466046 8-Br-cAMP increases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EGFR mRNA CTD PMID:22079614 9-cis-retinoic acid decreases expression EXP 6480464 Alitretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 acetylsalicylic acid increases expression EXP 6480464 Aspirin results in increased expression of EGFR mRNA CTD PMID:15456535 acrolein increases activity EXP 6480464 Acrolein results in increased activity of EGFR protein CTD PMID:11329622 acrolein increases phosphorylation ISO RGD:10511 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20153347 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:11329622 , PMID:15531749 acrolein increases phosphorylation ISO RGD:2543 6480464 Acrolein results in increased phosphorylation of EGFR protein CTD PMID:20359552 acrolein multiple interactions ISO RGD:2543 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]], Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 acrolein multiple interactions EXP 6480464 EGFR protein affects the reaction [Acrolein results in increased expression of MUC5AC mRNA], RTKI cpd inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:15531749 acrylamide affects phosphorylation EXP 6480464 Acrylamide analog affects the phosphorylation of EGFR protein CTD PMID:11462982 acrylamide multiple interactions EXP 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein], epigallocatechin gallate inhibits the reaction [Acrylamide results in increased expression of EGFR protein] CTD PMID:24508477 acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of EGFR protein CTD PMID:24508477 acrylamide decreases phosphorylation EXP 6480464 Acrylamide analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 acteoside multiple interactions EXP 6480464 acteoside inhibits the reaction [[TNF protein co-treated with IFNG protein] results in increased phosphorylation of EGFR protein] more ... CTD PMID:21756928 , PMID:21967610 acteoside decreases phosphorylation EXP 6480464 acteoside results in decreased phosphorylation of EGFR protein CTD PMID:21756928 , PMID:21967610 actinomycin D multiple interactions ISO RGD:2543 6480464 Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein], Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 afatinib decreases phosphorylation EXP 6480464 afatinib results in decreased phosphorylation of EGFR protein CTD PMID:28787001 afatinib decreases activity EXP 6480464 afatinib results in decreased activity of EGFR protein, afatinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 , PMID:22242139 afimoxifene decreases response to substance EXP 6480464 EGFR protein results in decreased susceptibility to afimoxifene, EGFR results in decreased susceptibility to afimoxifene CTD PMID:18351453 , PMID:21233418 AH23848 multiple interactions EXP 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] inhibits the reaction [EGFR protein modified form binds to SRC protein], [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in decreased phosphorylation of and results in decreased expression of EGFR protein CTD PMID:19407222 AICA ribonucleotide multiple interactions EXP 6480464 AICA ribonucleotide inhibits the reaction [EGFR protein results in increased import of Deoxyglucose] CTD PMID:19625624 aldosterone increases expression ISO RGD:2543 6480464 Aldosterone results in increased expression of EGFR mRNA CTD PMID:11507004 all-trans-4-oxoretinoic acid decreases expression EXP 6480464 4-oxoretinoic acid results in decreased expression of EGFR mRNA CTD PMID:15982314 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin metabolite results in decreased expression of EGFR mRNA, Tretinoin results in decreased expression of EGFR protein CTD PMID:15970678 more ... all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:21934132 all-trans-retinoic acid increases phosphorylation ISO RGD:10511 6480464 Tretinoin results in increased phosphorylation of EGFR protein CTD PMID:16357442 all-trans-retinoic acid increases expression ISO RGD:10511 6480464 Tretinoin results in increased expression of EGFR mRNA CTD PMID:16604517 all-trans-retinoic acid multiple interactions ISO RGD:10511 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA, HBEGF protein promotes the reaction [Tretinoin results in increased phosphorylation of EGFR protein] CTD PMID:16357442 , PMID:30951980 all-trans-retinol increases expression ISO RGD:2543 6480464 Vitamin A deficiency results in increased expression of EGFR mRNA CTD PMID:7519440 alpha-naphthoflavone multiple interactions EXP 6480464 alpha-naphthoflavone inhibits the reaction [Tetrachlorodibenzodioxin results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:17934341 alprenolol multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Alprenolol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 alprenolol increases phosphorylation EXP 6480464 [Alprenolol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 aluminium oxide increases expression EXP 6480464 Aluminum Oxide results in increased expression of EGFR mRNA CTD PMID:19464052 AM-251 multiple interactions EXP 6480464 4'-methoxy-1-naphthylfenoterol inhibits the reaction [AM 251 results in increased expression of EGFR protein] more ... CTD PMID:27423937 AM-251 increases expression EXP 6480464 AM 251 results in increased expression of EGFR protein CTD PMID:27423937 amiodarone decreases expression ISO RGD:10511 6480464 Amiodarone results in decreased expression of EGFR mRNA CTD PMID:24535564 ammonium chloride affects expression ISO RGD:2543 6480464 Ammonium Chloride affects the expression of EGFR mRNA CTD PMID:16483693 ammonium chloride decreases expression ISO RGD:2543 6480464 Ammonium Chloride results in decreased expression of EGFR protein CTD PMID:16483693 amosite asbestos decreases phosphorylation EXP 6480464 Asbestos, Amosite results in decreased phosphorylation of EGFR protein CTD PMID:15626777 amosite asbestos increases expression ISO RGD:2543 6480464 Asbestos, Amosite results in increased expression of EGFR mRNA CTD PMID:22251266 amphibole asbestos increases expression ISO RGD:2543 6480464 Asbestos, Amphibole results in increased expression of EGFR mRNA CTD PMID:22251266 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression EXP 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA, pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:15923621 anthra[1,9-cd]pyrazol-6(2H)-one decreases expression ISO RGD:2543 6480464 pyrazolanthrone results in decreased expression of EGFR mRNA, pyrazolanthrone results in decreased expression of EGFR protein CTD PMID:18332871 antimonite increases expression EXP 6480464 antimonite results in increased expression of EGFR protein CTD PMID:17400267 antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of EGFR mRNA CTD PMID:24449571 ANTU increases expression ISO RGD:2543 6480464 alpha-naphthyl thiourea results in increased expression of EGFR mRNA CTD PMID:10755703 apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 arachidonic acid multiple interactions ISO RGD:2543 6480464 5 more ... CTD PMID:15525798 arecoline multiple interactions ISO RGD:10511 6480464 [Arecoline co-treated with 4-nitroquinolone-1-oxide] results in increased phosphorylation of EGFR protein more ... CTD PMID:26464283 arsane increases expression EXP 6480464 Arsenic results in increased expression of EGFR mRNA, Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 , PMID:19945496 arsenic acid increases phosphorylation EXP 6480464 arsenic acid results in increased phosphorylation of EGFR protein CTD PMID:14674888 arsenic acid multiple interactions EXP 6480464 EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK1 protein], EGFR protein affects the reaction [arsenic acid results in increased activity of MAPK3 protein] CTD PMID:14674888 arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of EGFR mRNA, Arsenic results in increased expression of EGFR protein alternative form CTD PMID:17453740 , PMID:19945496 arsenite(3-) decreases degradation EXP 6480464 arsenite results in decreased degradation of EGFR protein CTD PMID:17400267 arsenite(3-) increases methylation EXP 6480464 arsenite results in increased methylation of EGFR promoter CTD PMID:23974009 arsenite(3-) multiple interactions EXP 6480464 EGFR protein affects the reaction [arsenite results in increased activity of MAPK1 protein], EGFR protein affects the reaction [arsenite results in increased activity of MAPK3 protein] CTD PMID:14674888 arsenite(3-) increases phosphorylation EXP 6480464 arsenite results in increased phosphorylation of EGFR protein CTD PMID:14674888 , PMID:17400267 arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of EGFR protein CTD PMID:17400267 arsenous acid multiple interactions ISO RGD:10511 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 arsenous acid affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide, EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 , PMID:30237564 arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA, Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... arsenous acid decreases expression ISO RGD:10511 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 , PMID:29274334 arsenous acid multiple interactions EXP 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... atenolol multiple interactions EXP 6480464 Atenolol inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased phosphorylation of EGFR protein] CTD PMID:16671086 atorvastatin calcium multiple interactions ISO RGD:10511 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:18360054 ATP multiple interactions EXP 6480464 sodium arsenite promotes the reaction [Adenosine Triphosphate results in increased phosphorylation of EGFR protein] CTD PMID:26104857 ATP increases phosphorylation EXP 6480464 Adenosine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:26104857 atrazine increases expression EXP 6480464 Atrazine results in increased expression of EGFR mRNA CTD PMID:22378314 atrazine multiple interactions EXP 6480464 Atrazine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:29329451 atropine multiple interactions EXP 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 avobenzone increases expression EXP 6480464 avobenzone results in increased expression of EGFR mRNA CTD PMID:31016361 bafilomycin A1 multiple interactions EXP 6480464 bafilomycin A1 inhibits the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 baicalein multiple interactions EXP 6480464 baicalein inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 baicalin multiple interactions EXP 6480464 baicalin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 benzamide decreases activity EXP 6480464 benzamide analog results in decreased activity of EGFR protein CTD PMID:15186837 benzamidine decreases activity EXP 6480464 benzamidine analog results in decreased activity of EGFR protein CTD PMID:15186837 benzene decreases expression ISO RGD:2543 6480464 Benzene results in decreased expression of EGFR mRNA CTD PMID:17905399 benzo[a]pyrene increases phosphorylation EXP 6480464 Benzo(a)pyrene results in increased phosphorylation of EGFR protein CTD PMID:19181443 benzo[a]pyrene increases response to substance EXP 6480464 EGFR protein results in increased susceptibility to Benzo(a)pyrene CTD PMID:8608954 benzo[a]pyrene multiple interactions ISO RGD:10511 6480464 AHR protein affects the reaction [Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein]], Benzo(a)pyrene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 benzo[a]pyrene decreases expression ISO RGD:10511 6480464 Benzo(a)pyrene results in decreased expression of EGFR mRNA CTD PMID:19770486 , PMID:21803694 benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EGFR mRNA CTD PMID:19181443 benzo[a]pyrene diol epoxide I multiple interactions EXP 6480464 7 more ... CTD PMID:22457794 benzo[a]pyrene diol epoxide I multiple interactions ISO RGD:10511 6480464 7 more ... CTD PMID:6309801 benzo[a]pyrene diol epoxide I decreases expression EXP 6480464 7 more ... CTD PMID:19150397 benzo[b]fluoranthene multiple interactions EXP 6480464 benzo(b)fluoranthene affects the localization of and results in increased expression of EGFR protein CTD PMID:21776270 benzo[b]fluoranthene decreases expression ISO RGD:10511 6480464 benzo(b)fluoranthene results in decreased expression of EGFR mRNA CTD PMID:26377693 benzoic acid multiple interactions ISO RGD:10511 6480464 Benzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 betulin decreases phosphorylation EXP 6480464 betulin results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulin multiple interactions EXP 6480464 [Gefitinib co-treated with betulin] results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:27447558 betulinic acid increases phosphorylation EXP 6480464 betulinic acid results in increased phosphorylation of EGFR protein CTD PMID:16077934 betulinic acid multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16077934 , PMID:30136359 bicalutamide multiple interactions EXP 6480464 bicalutamide inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]] more ... CTD PMID:29383186 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:2543 6480464 Diethylhexyl Phthalate results in decreased expression of EGFR protein CTD PMID:2404574 bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of EGFR mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:20678512 bisphenol A decreases expression ISO RGD:2543 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:30816183 bisphenol A increases expression ISO RGD:10511 6480464 bisphenol A results in increased expression of EGFR mRNA CTD PMID:30951980 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EGFR mRNA, bisphenol A results in increased expression of EGFR protein CTD PMID:29275510 more ... bisphenol A multiple interactions EXP 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [bisphenol A results in increased phosphorylation of EGFR protein] more ... CTD PMID:28426875 more ... bisphenol A increases methylation ISO RGD:2543 6480464 bisphenol A results in increased methylation of EGFR gene CTD PMID:28505145 bisphenol A increases phosphorylation EXP 6480464 bisphenol A results in increased phosphorylation of EGFR protein CTD PMID:28426875 more ... bisphenol A increases expression ISO RGD:2543 6480464 bisphenol A results in increased expression of EGFR mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:10511 6480464 bisphenol A results in decreased expression of EGFR mRNA CTD PMID:26063408 bisphenol F multiple interactions ISO RGD:10511 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EGFR mRNA CTD PMID:30951980 bisphenol F increases expression ISO RGD:10511 6480464 bisphenol F results in increased expression of EGFR mRNA CTD PMID:30951980 bosutinib decreases activity ISO RGD:10511 6480464 bosutinib results in decreased activity of EGFR protein CTD PMID:18385429 butan-1-ol multiple interactions ISO RGD:2543 6480464 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:11134345 , PMID:15525798 butane-2,3-dione increases phosphorylation EXP 6480464 Diacetyl results in increased phosphorylation of EGFR protein CTD PMID:30851105 butane-2,3-dione multiple interactions EXP 6480464 N-((2-(hydroxyaminocarbonyl)methyl)-4-methylpentanoyl)-3-(2'-naphthyl)alanylalanine, 2-aminoethylamide inhibits the reaction [Diacetyl results in increased phosphorylation of EGFR protein] CTD PMID:30851105 butylated hydroxyanisole multiple interactions ISO RGD:10511 6480464 Butylated Hydroxyanisole inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:21220312 butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Particulate Matter results in increased phosphorylation of EGFR protein], Butylated Hydroxyanisole inhibits the reaction [Vehicle Emissions results in increased phosphorylation of EGFR protein] CTD PMID:17028263 Butylbenzyl phthalate multiple interactions EXP 6480464 fulvestrant inhibits the reaction [butylbenzyl phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 Butylbenzyl phthalate increases phosphorylation EXP 6480464 butylbenzyl phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 cadmium atom decreases expression ISO RGD:10511 6480464 Cadmium results in decreased expression of EGFR mRNA CTD PMID:22666406 cadmium atom increases phosphorylation EXP 6480464 Cadmium results in increased phosphorylation of EGFR protein CTD PMID:26514923 cadmium atom increases activity EXP 6480464 Cadmium results in increased activity of EGFR protein CTD PMID:25343777 cadmium atom multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:25343777 more ... cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of EGFR, Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:18560533 more ... cadmium dichloride increases phosphorylation EXP 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:25118938 , PMID:26385184 cadmium dichloride increases phosphorylation ISO RGD:10511 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:23948867 cadmium dichloride increases expression ISO RGD:10511 6480464 Cadmium Chloride results in increased expression of EGFR mRNA CTD PMID:23948867 cadmium dichloride multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:23673518 more ... cadmium dichloride multiple interactions ISO RGD:10511 6480464 4-(2-aminoethyl)benzenesulfonylfluoride inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:23376140 , PMID:23948867 cadmium dichloride increases phosphorylation ISO RGD:2543 6480464 Cadmium Chloride results in increased phosphorylation of EGFR protein CTD PMID:19233221 cadmium dichloride multiple interactions ISO RGD:2543 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein], RTKI cpd inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of EGFR mRNA CTD PMID:21592394 calcitriol multiple interactions ISO RGD:2543 6480464 Calcitriol results in increased expression of and binds to EGFR protein CTD PMID:3498716 calcitriol multiple interactions EXP 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 calcium atom multiple interactions ISO RGD:2543 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 calcium(0) multiple interactions ISO RGD:2543 6480464 Calcium affects the phosphorylation of and affects the expression of EGFR protein CTD PMID:8393775 canertinib decreases phosphorylation EXP 6480464 Canertinib results in decreased phosphorylation of EGFR protein CTD PMID:15956251 canertinib multiple interactions ISO RGD:10511 6480464 Canertinib inhibits the reaction [Acetaminophen affects the localization of EGFR protein], Canertinib inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:28123000 canertinib decreases activity EXP 6480464 Canertinib results in decreased activity of EGFR protein, Canertinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 canertinib multiple interactions EXP 6480464 Canertinib inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18927496 capsaicin decreases expression ISO RGD:2543 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:14521749 capsaicin multiple interactions ISO RGD:10511 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 capsaicin increases phosphorylation EXP 6480464 Capsaicin results in increased phosphorylation of EGFR protein CTD PMID:20619260 , PMID:20660715 capsaicin decreases expression EXP 6480464 Capsaicin results in decreased expression of EGFR protein CTD PMID:19855437 capsaicin multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Capsaicin results in increased phosphorylation of EGFR protein] more ... CTD PMID:20619260 more ... carbon nanotube affects expression ISO RGD:10511 6480464 Nanotubes, Carbon affects the expression of EGFR mRNA CTD PMID:23845593 carbon nanotube increases expression ISO RGD:10511 6480464 Nanotubes, Carbon analog results in increased expression of EGFR mRNA, Nanotubes, Carbon results in increased expression of EGFR mRNA CTD PMID:25554681 , PMID:25620056 carvedilol multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 carvedilol increases phosphorylation EXP 6480464 [carvedilol results in increased phosphorylation of ADRB1 protein] which results in increased phosphorylation of EGFR protein CTD PMID:18787115 casticin decreases expression ISO RGD:10511 6480464 casticin results in decreased expression of EGFR protein CTD PMID:28444820 celastrol multiple interactions EXP 6480464 [Sulfasalazine co-treated with tripterine] affects the expression of EGFR protein, [Sulfasalazine co-treated with tripterine] results in decreased expression of EGFR protein CTD PMID:20007406 celastrol decreases expression EXP 6480464 tripterine results in decreased expression of EGFR protein CTD PMID:17010675 celecoxib multiple interactions ISO RGD:2543 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein more ... CTD PMID:15309881 , PMID:17908994 chloroprene increases expression ISO RGD:2543 6480464 Chloroprene results in increased expression of EGFR mRNA CTD PMID:23125180 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [EGF protein results in decreased expression of EGFR protein] more ... CTD PMID:20332299 , PMID:22457794 chloroquine decreases expression EXP 6480464 Chloroquine results in decreased expression of EGFR protein CTD PMID:20332299 chlorothalonil decreases phosphorylation EXP 6480464 tetrachloroisophthalonitrile results in decreased phosphorylation of EGFR protein CTD PMID:28426875 chlorpyrifos increases phosphorylation EXP 6480464 Chlorpyrifos results in increased phosphorylation of EGFR protein CTD PMID:26514924 cholesterol multiple interactions ISO RGD:10511 6480464 [Cholesterol co-treated with 1, 2-dioleoyloxy-3-(trimethylammonium)propane] results in increased expression of EGFR mRNA CTD PMID:22129739 chromium(6+) increases expression EXP 6480464 chromium hexavalent ion results in increased expression of EGFR mRNA CTD PMID:19616015 chromium(6+) increases phosphorylation ISO RGD:10511 6480464 chromium hexavalent ion results in increased phosphorylation of EGFR protein CTD PMID:25477514 chromium(6+) decreases expression EXP 6480464 chromium hexavalent ion results in decreased expression of EGFR mRNA CTD PMID:18053681 chrysin multiple interactions EXP 6480464 chrysin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 ciglitazone multiple interactions EXP 6480464 ciglitazone inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 ciglitazone decreases expression EXP 6480464 ciglitazone results in decreased expression of EGFR protein CTD PMID:21080969 ciguatoxin CTX1B affects expression ISO RGD:10511 6480464 Ciguatoxins affects the expression of EGFR mRNA CTD PMID:18353800 cimetidine multiple interactions EXP 6480464 Cimetidine inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 cimetidine multiple interactions ISO RGD:10511 6480464 [Cimetidine results in decreased abundance of Cyclic AMP] inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:17295779 ciprofibrate decreases expression ISO RGD:2543 6480464 ciprofibrate results in decreased expression of EGFR protein CTD PMID:2404574 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with Fluorouracil] results in decreased expression of EGFR mRNA more ... CTD PMID:15737843 more ... cisplatin multiple interactions ISO RGD:10511 6480464 Cisplatin promotes the reaction [PRKDC protein binds to EGFR protein] CTD PMID:21266349 cisplatin increases response to substance EXP 6480464 EGFR protein results in increased susceptibility to Cisplatin CTD PMID:21324906 cisplatin affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Cisplatin CTD PMID:21431282 cisplatin decreases response to substance EXP 6480464 EGFR mRNA results in decreased susceptibility to Cisplatin, EGFR results in decreased susceptibility to Cisplatin CTD PMID:18337622 more ... cisplatin increases phosphorylation EXP 6480464 Cisplatin results in increased phosphorylation of EGFR protein CTD PMID:20726858 clofibrate decreases expression ISO RGD:10511 6480464 Clofibrate results in decreased expression of EGFR mRNA CTD PMID:17585979 clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:21080969 clofibrate multiple interactions EXP 6480464 Clofibrate inhibits the reaction [CREBBP protein binds to EGFR promoter] more ... CTD PMID:21080969 clofibrate decreases expression ISO RGD:2543 6480464 Clofibrate results in decreased expression of EGFR protein CTD PMID:2404574 clofibrate multiple interactions ISO RGD:10511 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of EGFR mRNA] CTD PMID:17585979 cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EGFR mRNA CTD PMID:19376846 cobalt dichloride decreases expression ISO RGD:2543 6480464 cobaltous chloride results in decreased expression of EGFR mRNA CTD PMID:24386269 cocaine decreases expression EXP 6480464 Cocaine results in decreased expression of EGFR mRNA CTD PMID:18000554 copper atom multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper atom decreases expression ISO RGD:10511 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(0) multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:18346929 more ... copper(0) decreases expression ISO RGD:10511 6480464 Copper results in decreased expression of EGFR mRNA CTD PMID:17205981 copper(II) sulfate increases phosphorylation EXP 6480464 Copper Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 crizotinib decreases response to substance EXP 6480464 EGFR protein mutant form results in decreased susceptibility to crizotinib, EGFR protein results in decreased susceptibility to crizotinib CTD PMID:21791641 , PMID:22235099 crizotinib multiple interactions EXP 6480464 [EGFR protein results in increased phosphorylation of EGFR protein] which results in decreased susceptibility to crizotinib more ... CTD PMID:22277784 , PMID:22553343 crocidolite asbestos increases activity EXP 6480464 Asbestos, Crocidolite results in increased activity of EGFR protein CTD PMID:21762757 crocidolite asbestos multiple interactions ISO RGD:2543 6480464 Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein], Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein] CTD PMID:26368632 crocidolite asbestos increases expression ISO RGD:2543 6480464 Asbestos, Crocidolite results in increased expression of EGFR mRNA, Asbestos, Crocidolite results in increased expression of EGFR protein CTD PMID:10783328 , PMID:26368632 crocidolite asbestos increases activity ISO RGD:10511 6480464 Asbestos, Crocidolite results in increased activity of EGFR protein CTD PMID:15520183 crocidolite asbestos multiple interactions ISO RGD:10511 6480464 Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased activity of EGFR protein] more ... CTD PMID:12154012 , PMID:15520183 crocidolite asbestos increases phosphorylation EXP 6480464 Asbestos, Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:16908449 crocidolite asbestos increases expression EXP 6480464 Asbestos, Crocidolite results in increased expression of EGFR protein CTD PMID:21570478 crocidolite asbestos increases phosphorylation ISO RGD:10511 6480464 Asbestos, Crocidolite results in increased phosphorylation of EGFR protein CTD PMID:14737115 crocidolite asbestos multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:15626777 , PMID:16908449 crocidolite asbestos affects binding EXP 6480464 Asbestos, Crocidolite binds to EGFR protein CTD PMID:23672436 curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [Acrylamide results in increased expression of EGFR protein] more ... CTD PMID:10851300 more ... curcumin decreases phosphorylation ISO RGD:2543 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:17372590 , PMID:18332871 curcumin decreases expression ISO RGD:2543 6480464 Curcumin results in decreased expression of EGFR mRNA, Curcumin results in decreased expression of EGFR protein CTD PMID:18332871 curcumin multiple interactions ISO RGD:2543 6480464 Curcumin inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA] CTD PMID:18006644 curcumin decreases phosphorylation EXP 6480464 Curcumin results in decreased phosphorylation of EGFR protein CTD PMID:15486348 curcumin decreases expression EXP 6480464 Curcumin analog results in decreased expression of EGFR mRNA more ... CTD PMID:15486348 more ... cycloheximide increases expression EXP 6480464 Cycloheximide results in increased expression of EGFR mRNA CTD PMID:15228094 cycloheximide multiple interactions EXP 6480464 Cycloheximide promotes the reaction [Arsenic Trioxide results in decreased expression of EGFR protein] CTD PMID:30237564 cycloheximide multiple interactions ISO RGD:2543 6480464 Cycloheximide inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein] CTD PMID:26368632 cyclophosphamide multiple interactions EXP 6480464 EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of EGFR mRNA CTD PMID:20106945 cyclosporin A decreases expression ISO RGD:10511 6480464 Cyclosporine results in decreased expression of EGFR mRNA CTD PMID:19770486 cypermethrin decreases expression ISO RGD:2543 6480464 cypermethrin results in decreased expression of EGFR mRNA, cypermethrin results in decreased expression of EGFR protein CTD PMID:22048644 cypermethrin decreases phosphorylation ISO RGD:2543 6480464 cypermethrin results in decreased phosphorylation of EGFR protein CTD PMID:22048644 cypermethrin affects binding ISO RGD:2543 6480464 cypermethrin binds to EGFR protein CTD PMID:22048644 cytochalasin B multiple interactions EXP 6480464 Cytochalasin B inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 cytochalasin D multiple interactions EXP 6480464 Cytochalasin D inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 dacomitinib multiple interactions ISO RGD:10511 6480464 dacomitinib inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein] CTD PMID:27491023 daidzein multiple interactions EXP 6480464 [daidzein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 DDE multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 Deguelin decreases expression EXP 6480464 deguelin metabolite results in decreased expression of EGFR protein, deguelin results in decreased expression of EGFR protein CTD PMID:19139008 dehydroepiandrosterone multiple interactions EXP 6480464 EGFR protein promotes the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA] CTD PMID:25969534 delphinidin decreases phosphorylation EXP 6480464 delphinidin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 deoxycholic acid increases activity EXP 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:16213893 deoxycholic acid multiple interactions EXP 6480464 Deoxycholic Acid results in decreased glycosylation of and results in decreased expression of EGFR protein more ... CTD PMID:14747693 , PMID:22223758 deoxycholic acid increases activity ISO RGD:2543 6480464 Deoxycholic Acid results in increased activity of EGFR protein CTD PMID:14747693 deoxycholic acid decreases response to substance EXP 6480464 EGFR protein results in decreased susceptibility to Deoxycholic Acid CTD PMID:12507930 deoxycholic acid increases phosphorylation EXP 6480464 Deoxycholic Acid results in increased phosphorylation of EGFR protein CTD PMID:14747693 desferrioxamine B multiple interactions EXP 6480464 Deferoxamine inhibits the reaction [Asbestos, Crocidolite results in decreased activity of and results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]] more ... CTD PMID:10807665 dexamethasone multiple interactions ISO RGD:2543 6480464 Dexamethasone results in decreased phosphorylation of and results in decreased activity of EGFR protein CTD PMID:15556944 diallyl trisulfide decreases expression EXP 6480464 diallyl trisulfide results in decreased expression of EGFR protein CTD PMID:23754639 diarsenic trioxide multiple interactions ISO RGD:10511 6480464 [Arsenic Trioxide co-treated with huachansu] results in decreased expression of EGFR protein CTD PMID:21434348 diarsenic trioxide affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Arsenic Trioxide, EGFR protein mutant form affects the susceptibility to Arsenic Trioxide CTD PMID:29535630 , PMID:30237564 diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of EGFR mRNA, Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:20435036 more ... diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EGFR protein CTD PMID:22532027 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of EGFR mRNA CTD PMID:22521957 , PMID:29274334 diarsenic trioxide multiple interactions EXP 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15961274 more ... diarsenic trioxide decreases expression ISO RGD:10511 6480464 Arsenic Trioxide results in decreased expression of EGFR protein CTD PMID:23029451 diazinon affects expression ISO RGD:2543 6480464 Diazinon affects the expression of EGFR mRNA CTD PMID:22546817 dibenziodolium multiple interactions ISO RGD:2543 6480464 diphenyleneiodonium inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:16391241 dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein] CTD PMID:26514923 dibutyl phthalate increases phosphorylation EXP 6480464 Dibutyl Phthalate results in increased phosphorylation of EGFR protein CTD PMID:22552774 dibutyl phthalate multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 dibutyl phthalate multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Dibutyl Phthalate results in increased phosphorylation of EGFR protein] CTD PMID:22552774 diclofenac increases expression ISO RGD:10511 6480464 Diclofenac results in increased expression of EGFR mRNA CTD PMID:26934552 dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of EGFR mRNA CTD PMID:28302478 dieldrin affects expression ISO RGD:2543 6480464 Dieldrin affects the expression of EGFR mRNA CTD PMID:22546817 diethylstilbestrol increases expression ISO RGD:2543 6480464 Diethylstilbestrol results in increased expression of EGFR mRNA CTD PMID:17011747 dimethylarsinic acid increases expression ISO RGD:2543 6480464 Cacodylic Acid results in increased expression of EGFR mRNA CTD PMID:16122865 dioxygen multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased chemical synthesis of Oxygen] CTD PMID:21300668 disodium selenite decreases expression ISO RGD:10511 6480464 Sodium Selenite results in decreased expression of EGFR mRNA CTD PMID:23274088 dobutamine decreases response to substance ISO RGD:10511 6480464 EGFR gene mutant form results in decreased susceptibility to Dobutamine CTD PMID:18599591 dobutamine multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Dobutamine promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]] more ... CTD PMID:18787115 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin increases phosphorylation EXP 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:30031762 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of EGFR mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:10511 6480464 Doxorubicin results in increased expression of EGFR mRNA CTD PMID:25896364 doxorubicin increases phosphorylation ISO RGD:10511 6480464 Doxorubicin results in increased phosphorylation of EGFR protein CTD PMID:17974986 doxorubicin multiple interactions ISO RGD:2543 6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:15843167 doxorubicin multiple interactions EXP 6480464 [[gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin, EGFR protein affects the susceptibility to [Cyclophosphamide co-treated with Doxorubicin co-treated with Fluorouracil] CTD PMID:15981280 , PMID:17938326 elemental selenium decreases expression EXP 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 epoxiconazole multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 equol multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Equol results in increased chemical synthesis of Oxygen] more ... CTD PMID:21300668 Erionite increases expression ISO RGD:2543 6480464 erionite results in increased expression of EGFR protein CTD PMID:26368632 erlotinib hydrochloride multiple interactions EXP 6480464 [Erlotinib Hydrochloride results in decreased activity of EGFR protein] which results in decreased expression of RAD50 protein more ... CTD PMID:19168569 more ... erlotinib hydrochloride decreases expression EXP 6480464 Erlotinib Hydrochloride results in decreased expression of EGFR protein modified form CTD PMID:30136359 erlotinib hydrochloride decreases phosphorylation EXP 6480464 Erlotinib Hydrochloride results in decreased phosphorylation of EGFR protein CTD PMID:16891461 more ... erlotinib hydrochloride decreases activity EXP 6480464 Erlotinib Hydrochloride results in decreased activity of EGFR protein CTD PMID:12907618 more ... erlotinib hydrochloride affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Erlotinib Hydrochloride, EGFR protein mutant form affects the susceptibility to Erlotinib Hydrochloride CTD PMID:21080748 erlotinib hydrochloride decreases response to substance EXP 6480464 EGFR protein mutant form results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:16407879 estrone multiple interactions ISO RGD:10511 6480464 Estrone inhibits the reaction [LEPR gene mutant form inhibits the reaction [EGFR protein results in increased phosphorylation of EGFR protein]], Estrone inhibits the reaction [LEPR gene mutant form results in decreased expression of EGFR mRNA] CTD PMID:1753381 ethanol increases expression ISO RGD:2543 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:15353170 ethanol increases expression ISO RGD:10511 6480464 Ethanol results in increased expression of EGFR mRNA CTD PMID:30319688 ethanol multiple interactions EXP 6480464 [Ethanol co-treated with CYP2E1 protein] results in increased phosphorylation of EGFR protein CTD PMID:22222162 ethanol decreases expression ISO RGD:10511 6480464 Ethanol results in decreased expression of EGFR mRNA CTD PMID:19167417 etoposide decreases expression EXP 6480464 Etoposide results in decreased expression of EGFR mRNA, Etoposide results in decreased expression of EGFR protein CTD PMID:15228094 eugenol decreases expression ISO RGD:10511 6480464 Eugenol results in decreased expression of EGFR protein CTD PMID:15618236 eugenol increases expression ISO RGD:10511 6480464 Eugenol results in increased expression of EGFR mRNA CTD PMID:15618236 everolimus multiple interactions EXP 6480464 platycodin D inhibits the reaction [Everolimus results in increased expression of EGFR protein] CTD PMID:28711525 everolimus increases expression EXP 6480464 Everolimus results in increased expression of EGFR mRNA, Everolimus results in increased expression of EGFR protein CTD PMID:28711525 Evodiamine multiple interactions ISO RGD:10511 6480464 EGFR mutant form inhibits the reaction [evodiamine results in increased phosphorylation of MAPK1 protein] more ... CTD PMID:19854188 Evodiamine increases phosphorylation ISO RGD:10511 6480464 evodiamine results in increased phosphorylation of EGFR protein CTD PMID:19854188 fenamidone increases expression ISO RGD:10511 6480464 fenamidone results in increased expression of EGFR mRNA CTD PMID:27029645 fenofibrate decreases expression ISO RGD:10511 6480464 Fenofibrate results in decreased expression of EGFR mRNA CTD PMID:11798191 ferric oxide increases phosphorylation ISO RGD:10511 6480464 ferric oxide analog results in increased phosphorylation of EGFR protein CTD PMID:24068039 fluoranthene multiple interactions ISO RGD:10511 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of EGFR mRNA CTD PMID:28329830 fluoxetine increases phosphorylation ISO RGD:10511 6480464 Fluoxetine results in increased phosphorylation of EGFR protein CTD PMID:18758753 fluoxetine multiple interactions ISO RGD:10511 6480464 [[Fluoxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:18758753 , PMID:19662385 flutamide decreases expression ISO RGD:2543 6480464 Flutamide results in decreased expression of EGFR mRNA CTD PMID:24136188 fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A promotes the reaction [EGFR protein binds to AR protein]] more ... CTD PMID:22552774 , PMID:29383186 furan decreases expression ISO RGD:2543 6480464 furan results in decreased expression of EGFR mRNA CTD PMID:25539665 galangin multiple interactions EXP 6480464 galangin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 gallic acid multiple interactions EXP 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:27087131 , PMID:27634460 gedunin decreases expression EXP 6480464 gedunin results in decreased expression of EGFR protein CTD PMID:17010675 gefitinib decreases response to substance EXP 6480464 EGFR gene mutant form results in decreased susceptibility to Gefitinib, EGFR protein mutant form results in decreased susceptibility to Gefitinib CTD PMID:16740687 more ... gefitinib decreases activity ISO RGD:2543 6480464 gefitinib results in decreased activity of EGFR protein CTD PMID:29228391 gefitinib multiple interactions ISO RGD:2543 6480464 gefitinib inhibits the reaction [HBEGF protein inhibits the reaction [sodium arsenite results in decreased phosphorylation of and results in decreased activity of EGFR protein]] CTD PMID:29228391 gefitinib decreases activity EXP 6480464 gefitinib results in decreased activity of EGFR protein CTD PMID:17938326 more ... gefitinib decreases phosphorylation EXP 6480464 Gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:13680161 more ... gefitinib decreases phosphorylation ISO RGD:2543 6480464 gefitinib results in decreased phosphorylation of EGFR protein CTD PMID:18375820 gefitinib decreases expression ISO RGD:2543 6480464 gefitinib results in decreased expression of EGFR protein modified form CTD PMID:15660382 gefitinib multiple interactions ISO RGD:10511 6480464 [gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene more ... CTD PMID:15841081 more ... gefitinib decreases expression EXP 6480464 Gefitinib results in decreased expression of EGFR protein modified form CTD PMID:19288272 , PMID:30136359 gefitinib multiple interactions EXP 6480464 [[Gefitinib results in decreased activity of EGFR protein] which affects the localization of ABCG2 protein] which results in decreased export of Doxorubicin more ... CTD PMID:13680161 more ... gefitinib increases response to substance EXP 6480464 EGFR gene mutant form results in increased susceptibility to gefitinib more ... CTD PMID:16115929 more ... gefitinib affects response to substance EXP 6480464 EGFR gene mutant form affects the susceptibility to Gefitinib more ... CTD PMID:15976335 more ... geldanamycin multiple interactions EXP 6480464 geldanamycin promotes the reaction [Sulfasalazine results in decreased expression of EGFR protein] CTD PMID:20007406 geldanamycin multiple interactions ISO RGD:2543 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9605431 geldanamycin multiple interactions ISO RGD:10511 6480464 geldanamycin inhibits the reaction [Tetrachlorodibenzodioxin inhibits the reaction [EGF protein binds to EGFR protein]] CTD PMID:9664232 geldanamycin decreases expression EXP 6480464 geldanamycin results in decreased expression of EGFR protein CTD PMID:20007406 gemcitabine multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... gemcitabine increases phosphorylation EXP 6480464 gemcitabine results in increased phosphorylation of EGFR protein CTD PMID:17146438 , PMID:20726858 gemcitabine increases expression EXP 6480464 gemcitabine results in increased expression of EGFR mRNA CTD PMID:17146438 gemcitabine decreases expression EXP 6480464 gemcitabine results in decreased expression of EGFR mRNA, gemcitabine results in decreased expression of EGFR protein CTD PMID:17146438 , PMID:20103597 gemcitabine increases degradation EXP 6480464 gemcitabine results in increased degradation of EGFR protein CTD PMID:17146438 genistein multiple interactions EXP 6480464 [Genistein co-treated with ESR1 protein] results in decreased expression of EGFR mRNA more ... CTD PMID:19347870 genistein multiple interactions ISO RGD:2543 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] CTD PMID:19059320 genistein increases expression ISO RGD:2543 6480464 Genistein results in increased expression of EGFR protein CTD PMID:15781664 genistein decreases expression ISO RGD:10511 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:11880592 genistein decreases expression EXP 6480464 Genistein results in decreased expression of EGFR mRNA CTD PMID:15257099 gentamycin increases expression ISO RGD:2543 6480464 Gentamicins results in increased expression of EGFR mRNA CTD PMID:22061828 glafenine decreases expression ISO RGD:2543 6480464 Glafenine results in decreased expression of EGFR mRNA CTD PMID:24136188 glutathione multiple interactions EXP 6480464 Glutathione inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] CTD PMID:14660655 glutathione multiple interactions ISO RGD:10511 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein, [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein], Go 6976 inhibits the reaction [irinotecan results in increased phosphorylation of EGFR protein] CTD PMID:15723263 Goe 6976 multiple interactions ISO RGD:2543 6480464 Go 6976 inhibits the reaction [EGF protein binds to and results in increased localization of EGFR protein] CTD PMID:11134345 gold atom multiple interactions EXP 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 gold(0) multiple interactions EXP 6480464 [Gallic Acid binds to Gold] inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:27634460 heparin decreases expression EXP 6480464 Heparin results in decreased expression of EGFR mRNA, Heparin results in decreased expression of EGFR protein CTD PMID:16475731 heparin increases phosphorylation EXP 6480464 Heparin results in increased phosphorylation of EGFR protein CTD PMID:16556679 hexachlorobenzene multiple interactions EXP 6480464 [AG 1879 results in decreased activity of SRC protein] inhibits the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein] more ... CTD PMID:21205633 , PMID:23462309 hexachlorobenzene increases expression ISO RGD:10511 6480464 Hexachlorobenzene results in increased expression of EGFR mRNA CTD PMID:28923513 hexachlorobenzene multiple interactions ISO RGD:10511 6480464 Hexachlorobenzene affects the reaction [AHR protein affects the expression of EGFR mRNA] CTD PMID:28923513 hexachlorobenzene multiple interactions ISO RGD:2543 6480464 AG 1879 inhibits the reaction [SRC protein promotes the reaction [Hexachlorobenzene results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18295415 , PMID:22245120 hexachlorobenzene increases phosphorylation ISO RGD:2543 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:18295415 hexachlorobenzene increases phosphorylation EXP 6480464 Hexachlorobenzene results in increased phosphorylation of EGFR protein CTD PMID:21205633 hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 histamine multiple interactions EXP 6480464 EGFR protein affects the reaction [Histamine results in increased secretion of MMP1 protein] CTD PMID:17656145 hyaluronic acid multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [FSHB protein results in increased chemical synthesis of Hyaluronic Acid] CTD PMID:21520325 hydrogen chloride multiple interactions ISO RGD:2543 6480464 celecoxib promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] more ... CTD PMID:15309881 hydrogen chloride increases expression ISO RGD:2543 6480464 Hydrochloric Acid results in increased expression of EGFR protein CTD PMID:15309881 hydrogen peroxide increases phosphorylation ISO RGD:2543 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:19885844 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of EGFR protein CTD PMID:21179406 hydrogen peroxide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:10640773 , PMID:26514923 hydrogen peroxide multiple interactions ISO RGD:10511 6480464 AG 1879 inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EGFR protein] CTD PMID:14737115 hydrogen peroxide increases phosphorylation ISO RGD:10511 6480464 Hydrogen Peroxide results in increased phosphorylation of EGFR protein CTD PMID:14737115 hydroxamic acid multiple interactions ISO RGD:10511 6480464 Hydroxamic Acids analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]] CTD PMID:26088127 hypochlorous acid multiple interactions EXP 6480464 Hypochlorous Acid results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18156441 icariside II multiple interactions EXP 6480464 baohuoside I inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25119583 icariside II decreases phosphorylation EXP 6480464 baohuoside I results in decreased phosphorylation of EGFR protein CTD PMID:25119583 indole-3-methanol decreases expression EXP 6480464 indole-3-carbinol results in decreased expression of EGFR protein CTD PMID:18025290 indometacin increases expression ISO RGD:10511 6480464 Indomethacin results in increased expression of EGFR protein CTD PMID:17977527 indometacin multiple interactions ISO RGD:2543 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA], Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 indometacin increases expression ISO RGD:2543 6480464 Indomethacin results in increased expression of EGFR mRNA CTD PMID:29523851 indometacin multiple interactions ISO RGD:10511 6480464 malabaricone B promotes the reaction [Indomethacin results in increased expression of EGFR protein], malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 irbesartan multiple interactions ISO RGD:2543 6480464 Irbesartan inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 irinotecan multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15723263 isoprenaline increases expression ISO RGD:10511 6480464 Isoproterenol results in increased expression of EGFR mRNA CTD PMID:20003209 isoprenaline multiple interactions EXP 6480464 Isoproterenol promotes the reaction [ADRB1 protein results in increased uptake of EGFR protein] CTD PMID:18787115 isotretinoin decreases expression EXP 6480464 Isotretinoin results in decreased expression of EGFR mRNA CTD PMID:15982314 ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 KN-93 multiple interactions ISO RGD:2543 6480464 KN 93 inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:19233221 L-ascorbic acid decreases expression EXP 6480464 Ascorbic Acid results in decreased expression of EGFR mRNA CTD PMID:21919647 lansoprazole increases expression EXP 6480464 Lansoprazole results in increased expression of EGFR protein CTD PMID:9881512 lapatinib decreases activity EXP 6480464 lapatinib results in decreased activity of EGFR protein CTD PMID:15665275 more ... lapatinib multiple interactions EXP 6480464 KRAS protein affects the reaction [EGFR protein affects the susceptibility to Lapatinib] more ... CTD PMID:28739874 lapatinib affects response to substance EXP 6480464 EGFR protein affects the susceptibility to lapatinib CTD PMID:28739874 lead diacetate decreases expression ISO RGD:2543 6480464 lead acetate results in decreased expression of EGFR protein CTD PMID:17298174 lead diacetate increases phosphorylation EXP 6480464 lead acetate results in increased phosphorylation of EGFR protein CTD PMID:19133285 lead diacetate multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:19133285 lead nitrate multiple interactions EXP 6480464 EGFR mutant form affects the reaction [[lead nitrate results in increased expression of PLA2G4A mRNA] which results in increased secretion of Dinoprostone] more ... CTD PMID:20850495 lead nitrate increases phosphorylation EXP 6480464 lead nitrate results in increased phosphorylation of EGFR protein CTD PMID:20850495 lead(0) decreases expression ISO RGD:2543 6480464 Lead results in decreased expression of EGFR protein CTD PMID:17298174 lead(2+) decreases expression ISO RGD:2543 6480464 Lead results in decreased expression of EGFR protein CTD PMID:17298174 leflunomide increases expression EXP 6480464 leflunomide results in increased expression of EGFR mRNA CTD PMID:28988120 leflunomide multiple interactions EXP 6480464 Leflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 leukotriene C4 increases expression ISO RGD:10511 6480464 Leukotriene C4 results in increased expression of EGFR mRNA CTD PMID:12388339 linalool increases expression EXP 6480464 linalool results in increased expression of EGFR mRNA CTD PMID:19922762 linuron multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 linuron decreases expression ISO RGD:2543 6480464 Linuron results in decreased expression of EGFR mRNA CTD PMID:12730624 lipopolysaccharide increases phosphorylation ISO RGD:10511 6480464 Lipopolysaccharides results in increased phosphorylation of EGFR protein CTD PMID:21874253 , PMID:23099361 lipopolysaccharide multiple interactions ISO RGD:10511 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein], TLR4 mutant form promotes the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:21874253 , PMID:23099361 lithium chloride multiple interactions EXP 6480464 [Lithium Chloride results in decreased activity of and results in increased phosphorylation of GSK3B protein] which results in increased expression of EGFR mRNA more ... CTD PMID:22493441 lithium chloride increases expression EXP 6480464 Lithium Chloride results in increased expression of EGFR mRNA, Lithium Chloride results in increased expression of EGFR protein CTD PMID:22493441 lovastatin multiple interactions EXP 6480464 Lovastatin inhibits the reaction [EGF protein promotes the reaction [EGFR protein results in increased phosphorylation of EGFR protein]], Lovastatin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:12942316 , PMID:19760159 luteolin multiple interactions EXP 6480464 EGF protein inhibits the reaction [Luteolin results in decreased phosphorylation of EGFR protein] more ... CTD PMID:10556937 more ... luteolin decreases expression EXP 6480464 Luteolin results in decreased expression of EGFR mRNA CTD PMID:22926442 luteolin affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Luteolin CTD PMID:12168845 LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 magnesium dichloride multiple interactions EXP 6480464 [Magnesium Chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 Malabaricone C multiple interactions ISO RGD:10511 6480464 malabaricone C promotes the reaction [Indomethacin results in increased expression of EGFR protein] CTD PMID:17977527 manganese(II) chloride multiple interactions EXP 6480464 [manganese chloride co-treated with EGF protein] results in increased activity of EGFR protein CTD PMID:2354210 manganese(II) chloride increases expression ISO RGD:2543 6480464 manganese chloride results in increased expression of EGFR mRNA CTD PMID:28801915 manganese(II) chloride increases activity EXP 6480464 manganese chloride results in increased activity of EGFR protein CTD PMID:2354210 melittin increases activity EXP 6480464 Melitten results in increased activity of EGFR protein CTD PMID:22613720 menadione increases phosphorylation ISO RGD:2543 6480464 Vitamin K 3 results in increased phosphorylation of EGFR protein CTD PMID:15843167 mercury dichloride increases expression ISO RGD:2543 6480464 Mercuric Chloride results in increased expression of EGFR mRNA CTD PMID:10901180 metamizole sodium multiple interactions ISO RGD:2543 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 methapyrilene decreases expression ISO RGD:2543 6480464 Methapyrilene results in decreased expression of EGFR mRNA CTD PMID:30467583 methotrexate decreases response to substance ISO RGD:10511 6480464 EGFR mRNA results in decreased susceptibility to Methotrexate CTD PMID:16918715 methotrexate increases expression ISO RGD:2543 6480464 Methotrexate results in increased expression of EGFR mRNA CTD PMID:18803016 methoxychlor increases expression ISO RGD:2543 6480464 Methoxychlor results in increased expression of EGFR protein CTD PMID:8888411 methoxychlor increases phosphorylation EXP 6480464 Methoxychlor results in increased phosphorylation of EGFR protein CTD PMID:28426875 methoxychlor multiple interactions ISO RGD:2543 6480464 Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 Methylazoxymethanol acetate increases expression ISO RGD:2543 6480464 Methylazoxymethanol Acetate results in increased expression of EGFR mRNA CTD PMID:28349193 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of EGFR protein CTD PMID:28958600 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of EGFR mRNA CTD PMID:28001369 microcystin-LR increases expression EXP 6480464 cyanoginosin LR results in increased expression of EGFR mRNA CTD PMID:29518473 microcystin-LR decreases methylation EXP 6480464 cyanoginosin LR results in decreased methylation of EGFR gene CTD PMID:29518473 mifepristone multiple interactions EXP 6480464 Mifepristone inhibits the reaction [Dexamethasone inhibits the reaction [EGF protein promotes the reaction [EGFR protein binds to ARAF protein]]] more ... CTD PMID:10807665 mifepristone decreases expression ISO RGD:2543 6480464 Mifepristone results in decreased expression of EGFR mRNA CTD PMID:18591650 , PMID:25972201 MK-2206 multiple interactions EXP 6480464 platycodin D inhibits the reaction [MK 2206 results in increased expression of EGFR protein] CTD PMID:27897231 MK-2206 increases expression EXP 6480464 MK 2206 results in increased expression of EGFR protein CTD PMID:27897231 monosodium L-glutamate decreases expression ISO RGD:2543 6480464 Sodium Glutamate results in decreased expression of EGFR mRNA CTD PMID:28954212 myo-inositol hexakisphosphate multiple interactions EXP 6480464 Phytic Acid inhibits the reaction [Asbestos, Crocidolite results in decreased phosphorylation of EGFR protein] CTD PMID:15626777 myricetin multiple interactions ISO RGD:10511 6480464 myricetin promotes the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18995957 myricetin decreases phosphorylation ISO RGD:10511 6480464 myricetin results in decreased phosphorylation of EGFR protein CTD PMID:18995957 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Lithium Chloride results in increased expression of EGFR mRNA] CTD PMID:22493441 N-acetyl-L-cysteine multiple interactions ISO RGD:10511 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15520183 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:2543 6480464 Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] more ... CTD PMID:15849355 more ... N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein] more ... CTD PMID:10640773 more ... N-acetylcysteamine decreases phosphorylation EXP 6480464 2-acetamidoethanethiol analog results in decreased phosphorylation of EGFR protein CTD PMID:20058253 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [gemcitabine results in increased phosphorylation of and results in increased degradation of EGFR protein] more ... CTD PMID:17146438 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of EGFR protein CTD PMID:20332299 N-BUTYL-11-[(7R,8R,9S,13S,14S,17S)-3,17-DIHYDROXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-7-YL]-N-METHYLUNDECANAMIDE multiple interactions EXP 6480464 ICI 164384 inhibits the reaction [[Estradiol co-treated with EGFR protein] results in increased expression of SIAH2 mRNA] CTD PMID:18629630 N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:10511 6480464 Ethylnitrosourea results in increased mutagenesis of EGFR gene CTD PMID:15366372 , PMID:16724327 N-methyl-N'-nitro-N-nitrosoguanidine affects localization EXP 6480464 Methylnitronitrosoguanidine affects the localization of EGFR protein CTD PMID:15708576 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions EXP 6480464 Methylnitronitrosoguanidine inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:15708576 N-methyl-N-nitrosourea multiple interactions ISO RGD:2543 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:22245120 , PMID:25164625 N-methylformamide decreases expression ISO RGD:10511 6480464 methylformamide analog results in decreased expression of EGFR mRNA, methylformamide results in decreased expression of EGFR mRNA CTD PMID:17040096 N-nitrosodiethylamine multiple interactions ISO RGD:10511 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA more ... CTD PMID:17942915 more ... N-nitrosodiethylamine increases expression ISO RGD:10511 6480464 Diethylnitrosamine results in increased expression of EGFR mRNA CTD PMID:27058323 N-nitrosodiethylamine decreases expression ISO RGD:2543 6480464 Diethylnitrosamine results in decreased expression of EGFR mRNA, Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:15660382 , PMID:19638242 N-nitrosodiethylamine multiple interactions ISO RGD:2543 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:28943392 more ... N-nitrosodiethylamine decreases expression ISO RGD:10511 6480464 Diethylnitrosamine results in decreased expression of EGFR protein CTD PMID:20583210 N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO RGD:2543 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 naphthalene multiple interactions ISO RGD:10511 6480464 [gefitinib results in decreased activity of EGFR protein] which results in increased susceptibility to naphthalene CTD PMID:20935109 naringin multiple interactions EXP 6480464 naringin inhibits the reaction [EGF protein results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:22766066 nefazodone decreases expression ISO RGD:2543 6480464 nefazodone results in decreased expression of EGFR mRNA CTD PMID:24136188 neocuproine multiple interactions EXP 6480464 [Copper binds to neocuproine] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 neratinib decreases activity EXP 6480464 neratinib results in decreased activity of EGFR protein, neratinib results in decreased activity of EGFR protein mutant form CTD PMID:21322567 , PMID:22242139 nevirapine decreases expression EXP 6480464 Nevirapine results in decreased expression of EGFR mRNA CTD PMID:19152342 nickel dichloride affects expression ISO RGD:2543 6480464 nickel chloride affects the expression of EGFR mRNA CTD PMID:22546817 nickel dichloride increases expression EXP 6480464 nickel chloride results in increased expression of EGFR protein CTD PMID:26026961 nickel dichloride multiple interactions EXP 6480464 RECK protein inhibits the reaction [nickel chloride results in increased expression of EGFR protein] CTD PMID:26026961 nickel subsulfide increases expression ISO RGD:2543 6480464 nickel subsulfide results in increased expression of EGFR mRNA CTD PMID:21086188 nickel sulfate multiple interactions ISO RGD:10511 6480464 [TGFA protein binds to and affects the activity of EGFR protein] which results in decreased susceptibility to nickel sulfate CTD PMID:19131640 Niclosamide decreases phosphorylation EXP 6480464 Niclosamide results in decreased phosphorylation of EGFR protein CTD PMID:28426875 Niclosamide decreases expression EXP 6480464 Niclosamide analog results in decreased expression of EGFR protein, Niclosamide results in decreased expression of EGFR protein CTD PMID:28284560 nicotine increases phosphorylation EXP 6480464 Nicotine results in increased phosphorylation of EGFR protein CTD PMID:14569062 nicotine decreases expression ISO RGD:2543 6480464 Nicotine results in decreased expression of EGFR mRNA CTD PMID:11478936 nicotine multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Nicotine results in increased phosphorylation of EGFR protein] CTD PMID:14569062 O-methyleugenol decreases expression ISO RGD:10511 6480464 methyleugenol results in decreased expression of EGFR protein CTD PMID:15618236 ochratoxin A increases phosphorylation ISO RGD:10511 6480464 ochratoxin A results in increased phosphorylation of EGFR protein CTD PMID:23172667 oleic acid increases phosphorylation EXP 6480464 Oleic Acid results in increased phosphorylation of EGFR protein CTD PMID:27447558 oleic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA CTD PMID:30547786 osimertinib multiple interactions EXP 6480464 osimertinib affects the reaction [EGF protein results in increased phosphorylation of EGFR protein] more ... CTD PMID:30623574 , PMID:30993382 osimertinib decreases activity EXP 6480464 osimertinib results in decreased activity of EGFR protein CTD PMID:28237877 ouabain decreases phosphorylation EXP 6480464 Ouabain results in decreased phosphorylation of EGFR protein CTD PMID:28795476 oxaliplatin increases phosphorylation EXP 6480464 oxaliplatin results in increased phosphorylation of EGFR protein CTD PMID:16243822 oxaliplatin multiple interactions ISO RGD:2543 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 oxaliplatin multiple interactions EXP 6480464 [gefitinib co-treated with oxaliplatin] results in decreased phosphorylation of EGFR protein, EGFR gene polymorphism affects the susceptibility to [oxaliplatin co-treated with Fluorouracil] CTD PMID:13680161 , PMID:16098254 oxazepam decreases expression ISO RGD:10511 6480464 Oxazepam results in decreased expression of EGFR mRNA, Oxazepam results in decreased expression of EGFR protein CTD PMID:15618236 oxytocin increases expression ISO RGD:2543 6480464 Oxytocin results in increased expression of EGFR protein modified form CTD PMID:23707249 ozone multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein] more ... CTD PMID:19536146 , PMID:25303742 ozone increases phosphorylation ISO RGD:10511 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:26464147 ozone multiple interactions ISO RGD:10511 6480464 4-((3-bromophenyl)amino)-6, 7-dimethoxyquinazoline inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein] CTD PMID:26464147 ozone increases phosphorylation EXP 6480464 Ozone results in increased phosphorylation of EGFR protein CTD PMID:19536146 , PMID:25303742 p-chloromercuribenzoic acid decreases expression EXP 6480464 p-Chloromercuribenzoic Acid results in decreased expression of EGFR mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of EGFR mRNA CTD PMID:27188386 p-tert-Amylphenol increases expression ISO RGD:2543 6480464 4-tert-octylphenol results in increased expression of EGFR mRNA CTD PMID:17011747 paclitaxel increases phosphorylation EXP 6480464 Paclitaxel results in increased phosphorylation of EGFR protein CTD PMID:16211241 , PMID:20726858 paclitaxel decreases expression EXP 6480464 Paclitaxel results in decreased expression of EGFR mRNA CTD PMID:18058816 paclitaxel multiple interactions EXP 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein, Paclitaxel promotes the reaction [HER3 protein binds to EGFR protein] CTD PMID:16413505 , PMID:20726858 paracetamol multiple interactions ISO RGD:10511 6480464 [Acetaminophen results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein more ... CTD PMID:17585979 , PMID:28123000 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EGFR mRNA CTD PMID:29067470 paracetamol affects localization ISO RGD:10511 6480464 Acetaminophen affects the localization of EGFR protein CTD PMID:28123000 paracetamol multiple interactions EXP 6480464 Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of EGFR mRNA CTD PMID:21420995 paracetamol decreases expression ISO RGD:10511 6480464 Acetaminophen results in decreased expression of EGFR mRNA, Acetaminophen results in decreased expression of EGFR protein CTD PMID:15618236 , PMID:24126418 paraquat decreases expression ISO RGD:2543 6480464 Paraquat results in decreased expression of EGFR protein CTD PMID:17298174 parathion multiple interactions EXP 6480464 [Parathion co-treated with Estradiol] results in increased expression of EGFR protein, Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 , PMID:17622325 parathion increases expression EXP 6480464 Parathion results in increased expression of EGFR protein CTD PMID:17390078 , PMID:17622325 paroxetine multiple interactions ISO RGD:10511 6480464 [[Paroxetine binds to and results in increased activity of HTR2C protein] which results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of and results in increased activity of MAPK1 protein more ... CTD PMID:19662385 PD 168393 multiple interactions EXP 6480464 [PD168393 co-treated with Paclitaxel] results in decreased phosphorylation of EGFR protein more ... CTD PMID:16413505 more ... PD 168393 multiple interactions ISO RGD:2543 6480464 PD168393 inhibits the reaction [AGT protein results in increased phosphorylation of EGFR protein] CTD PMID:25398788 PD 168393 affects localization EXP 6480464 PD168393 affects the localization of EGFR protein, PD168393 affects the localization of EGFR protein modified form CTD PMID:21967610 PD 168393 decreases phosphorylation EXP 6480464 PD168393 results in decreased phosphorylation of EGFR protein CTD PMID:21967610 , PMID:23527233 pentane-2,3-dione increases expression ISO RGD:2543 6480464 2, 3-pentanedione results in increased expression of EGFR mRNA CTD PMID:25710175 perfluorooctane-1-sulfonic acid increases expression ISO RGD:2543 6480464 perfluorooctane sulfonic acid results in increased expression of EGFR mRNA, perfluorooctane sulfonic acid results in increased expression of EGFR protein CTD PMID:21251948 perfluorooctane-1-sulfonic acid increases phosphorylation ISO RGD:10511 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of EGFR protein CTD PMID:28288859 perfluorooctanoic acid decreases expression ISO RGD:2543 6480464 perfluorooctanoic acid results in decreased expression of EGFR mRNA CTD PMID:16221955 perfluorooctanoic acid decreases expression ISO RGD:10511 6480464 perfluorooctanoic acid results in decreased expression of EGFR protein CTD PMID:22414604 perfluorooctanoic acid multiple interactions ISO RGD:10511 6480464 Estradiol inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein] more ... CTD PMID:22414604 perfluorooctanoic acid increases expression ISO RGD:10511 6480464 perfluorooctanoic acid results in increased expression of EGFR protein CTD PMID:20118188 PHA-665752 multiple interactions EXP 6480464 [5-((2 more ... CTD PMID:21266357 PHA-665752 decreases phosphorylation EXP 6480464 5-((2 more ... CTD PMID:21266357 phenobarbital multiple interactions ISO RGD:10511 6480464 NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of EGFR mRNA], Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:19482888 , PMID:6309801 phenobarbital multiple interactions EXP 6480464 Phenobarbital inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:25625231 , PMID:30364229 phenobarbital affects expression ISO RGD:10511 6480464 Phenobarbital affects the expression of EGFR mRNA CTD PMID:19136022 , PMID:23091169 phenobarbital decreases expression ISO RGD:2543 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19162173 phenobarbital decreases expression ISO RGD:10511 6480464 Phenobarbital results in decreased expression of EGFR mRNA CTD PMID:19482888 phenobarbital multiple interactions ISO RGD:2543 6480464 Phenobarbital inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:10828207 phenylarsine oxide multiple interactions ISO RGD:10511 6480464 oxophenylarsine inhibits the reaction [EGF protein binds to and affects the localization of EGFR protein] CTD PMID:12093727 phenylephrine multiple interactions ISO RGD:10511 6480464 Atorvastatin inhibits the reaction [Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein], Phenylephrine results in increased expression of and results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:18360054 phenylephrine increases phosphorylation ISO RGD:2543 6480464 Phenylephrine results in increased phosphorylation of EGFR protein CTD PMID:14676212 phenylephrine multiple interactions ISO RGD:2543 6480464 [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK1 protein], [EGF protein binds to EGFR protein] promotes the reaction [Phenylephrine results in increased phosphorylation of MAPK3 protein] CTD PMID:16760267 phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of EGFR mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 PhIP increases expression ISO RGD:2543 6480464 2-amino-1-methyl-6-phenylimidazo(4, 5-b)pyridine results in increased expression of EGFR mRNA CTD PMID:8603490 phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10511 6480464 [Tetradecanoylphorbol Acetate co-treated with Capsaicin] results in increased phosphorylation of EGFR protein more ... CTD PMID:20660715 more ... phorbol 13-acetate 12-myristate increases phosphorylation ISO RGD:10511 6480464 Tetradecanoylphorbol Acetate results in increased phosphorylation of EGFR protein CTD PMID:26513295 phorbol 13-acetate 12-myristate increases expression ISO RGD:10511 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR CTD PMID:26100520 phorbol 13-acetate 12-myristate increases expression EXP 6480464 Tetradecanoylphorbol Acetate results in increased expression of EGFR protein CTD PMID:19447859 , PMID:25866363 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 naringenin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein], pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 , PMID:25866363 phorone multiple interactions ISO RGD:10511 6480464 [phorone results in decreased abundance of Glutathione] which results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:28123000 phosphoramidon multiple interactions EXP 6480464 phosphoramidon inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 piperonyl butoxide multiple interactions ISO RGD:10511 6480464 [Diethylnitrosamine co-treated with Piperonyl Butoxide] results in decreased expression of EGFR mRNA CTD PMID:20101389 pirfenidone multiple interactions EXP 6480464 [pirfenidone inhibits the reaction [EGFR protein binds to MAPK12 protein]] which results in decreased phosphorylation of PTPN3 protein more ... CTD PMID:28739874 pirinixic acid affects expression ISO RGD:10511 6480464 pirinixic acid affects the expression of EGFR mRNA CTD PMID:19136022 pirinixic acid decreases expression ISO RGD:10511 6480464 pirinixic acid results in decreased expression of EGFR mRNA CTD PMID:11798191 more ... pirinixic acid decreases expression ISO RGD:2543 6480464 pirinixic acid results in decreased expression of EGFR protein CTD PMID:2404574 pirinixic acid multiple interactions ISO RGD:10511 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of EGFR mRNA more ... CTD PMID:19710929 more ... piroxicam decreases expression EXP 6480464 Piroxicam results in decreased expression of EGFR mRNA CTD PMID:21858171 piroxicam multiple interactions ISO RGD:2543 6480464 Piroxicam promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 platycodin D decreases expression EXP 6480464 platycodin D results in decreased expression of EGFR protein CTD PMID:23867902 more ... platycodin D multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [platycodin D results in decreased expression of EGFR protein] more ... CTD PMID:27897231 , PMID:28711525 ponatinib decreases activity EXP 6480464 ponatinib results in decreased activity of EGFR protein mutant form CTD PMID:19878872 potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of EGFR mRNA CTD PMID:22079256 potassium chromate multiple interactions EXP 6480464 [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of EGFR mRNA CTD PMID:22079256 primaquine multiple interactions EXP 6480464 Primaquine inhibits the reaction [EGF protein results in increased uptake of and results in increased degradation of EGFR protein] CTD PMID:23125191 prochloraz multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 procymidone multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 progesterone multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] results in increased expression of EGFR mRNA more ... CTD PMID:16175315 more ... progesterone multiple interactions ISO RGD:2543 6480464 [Estrogens co-treated with Progesterone] results in increased expression of EGFR mRNA, [Estrogens co-treated with Progesterone] results in increased expression of EGFR protein CTD PMID:21258428 progesterone increases expression ISO RGD:2543 6480464 Progesterone results in increased expression of EGFR mRNA CTD PMID:18591650 progesterone multiple interactions ISO RGD:10511 6480464 Estradiol promotes the reaction [Progesterone inhibits the reaction [perfluorooctanoic acid results in decreased expression of EGFR protein]] more ... CTD PMID:22414604 progesterone increases expression EXP 6480464 Progesterone results in increased expression of EGFR protein CTD PMID:16175315 propranolol multiple interactions EXP 6480464 Propranolol inhibits the reaction [Alprenolol promotes the reaction [ADRB1 protein results in increased phosphorylation of EGFR protein]] more ... CTD PMID:18787115 prostaglandin E2 increases secretion EXP 6480464 EGFR protein results in increased secretion of Dinoprostone CTD PMID:16213893 prostaglandin E2 increases expression EXP 6480464 Dinoprostone results in increased expression of EGFR protein modified form CTD PMID:30208247 prostaglandin E2 multiple interactions EXP 6480464 cryptotanshinone inhibits the reaction [Dinoprostone results in increased expression of EGFR protein modified form] more ... CTD PMID:20850495 , PMID:30208247 prostaglandin E2 increases phosphorylation EXP 6480464 Dinoprostone results in increased phosphorylation of EGFR protein CTD PMID:17805209 protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [Ozone results in increased phosphorylation of EGFR protein] CTD PMID:25303742 protoporphyrin decreases expression EXP 6480464 protoporphyrin IX results in decreased expression of EGFR protein CTD PMID:23624237 Ptaquiloside decreases expression ISO RGD:10511 6480464 ptaquiloside results in decreased expression of EGFR mRNA CTD PMID:23274088 pterostilbene multiple interactions EXP 6480464 pterostilbene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR protein] CTD PMID:19447859 pyocyanine increases phosphorylation EXP 6480464 Pyocyanine results in increased phosphorylation of EGFR protein CTD PMID:24015256 pyrrolidine dithiocarbamate multiple interactions EXP 6480464 [Copper binds to pyrrolidine dithiocarbamic acid] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 quercetin affects response to substance EXP 6480464 EGFR protein affects the susceptibility to Quercetin CTD PMID:12168845 quercetin multiple interactions ISO RGD:10511 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EGFR protein] CTD PMID:23099361 quercetin decreases phosphorylation EXP 6480464 Quercetin results in decreased phosphorylation of EGFR protein CTD PMID:18618485 more ... quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of EGFR mRNA CTD PMID:21308698 quercetin multiple interactions ISO RGD:2543 6480464 Quercetin inhibits the reaction [[Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein] CTD PMID:25164625 quercetin multiple interactions EXP 6480464 [Cisplatin co-treated with Quercetin] results in increased expression of EGFR mRNA more ... CTD PMID:10556937 more ... quercetin 3-O-beta-D-glucofuranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quercetin 3-O-beta-D-glucopyranoside multiple interactions EXP 6480464 isoquercitrin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:26109002 quinazolines decreases phosphorylation EXP 6480464 Quinazolines analog results in decreased phosphorylation of EGFR protein CTD PMID:10753475 quinazolines multiple interactions EXP 6480464 Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK1 protein], Quinazolines analog inhibits the reaction [EGFR protein results in increased activity of MAPK3 protein] CTD PMID:21075094 quinolin-8-ol multiple interactions EXP 6480464 [Copper binds to Oxyquinoline] which results in increased phosphorylation of EGFR protein CTD PMID:18346929 rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of EGFR mRNA CTD PMID:30851411 raloxifene multiple interactions EXP 6480464 [Raloxifene Hydrochloride co-treated with epigallocatechin gallate] results in decreased phosphorylation of EGFR protein CTD PMID:18371987 raloxifene increases phosphorylation ISO RGD:2543 6480464 Raloxifene Hydrochloride results in increased phosphorylation of EGFR protein CTD PMID:24782323 ranitidine multiple interactions ISO RGD:2543 6480464 Ranitidine inhibits the reaction [Indomethacin results in increased expression of EGFR mRNA] CTD PMID:29523851 reactive oxygen species multiple interactions ISO RGD:10511 6480464 [[[[Cadmium Chloride results in increased abundance of Reactive Oxygen Species] which results in increased activity of SRC protein] which results in increased activity of EGFR protein] which results in increased activity of STAT3 protein] promotes the reaction [STAT3 protein binds to STAT3 protein] more ... CTD PMID:23376140 reactive oxygen species multiple interactions ISO RGD:2543 6480464 EGFR protein affects the reaction [Reactive Oxygen Species affects the phosphorylation of SHC1 protein] CTD PMID:19168439 resveratrol multiple interactions EXP 6480464 [resveratrol binds to EGFR protein] which results in decreased phosphorylation of EGFR protein more ... CTD PMID:16343977 more ... resveratrol decreases expression ISO RGD:10511 6480464 resveratrol results in decreased expression of EGFR mRNA CTD PMID:23525482 resveratrol increases activity EXP 6480464 resveratrol results in increased activity of EGFR protein CTD PMID:15802018 resveratrol decreases phosphorylation EXP 6480464 resveratrol results in decreased phosphorylation of EGFR protein CTD PMID:20729295 , PMID:23527233 resveratrol affects localization EXP 6480464 resveratrol affects the localization of EGFR protein, resveratrol affects the localization of EGFR protein modified form CTD PMID:23527233 resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of EGFR protein CTD PMID:23527233 resveratrol increases degradation EXP 6480464 resveratrol results in increased degradation of EGFR protein CTD PMID:23527233 resveratrol multiple interactions ISO RGD:10511 6480464 resveratrol inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR] more ... CTD PMID:26100520 resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of EGFR mRNA, resveratrol results in decreased expression of EGFR protein CTD PMID:24514079 , PMID:25667456 resveratrol affects binding EXP 6480464 resveratrol binds to EGFR protein CTD PMID:20729295 romidepsin decreases expression EXP 6480464 romidepsin results in decreased expression of EGFR protein CTD PMID:15014036 rotenone decreases expression ISO RGD:2543 6480464 Rotenone results in decreased expression of EGFR mRNA, Rotenone results in decreased expression of EGFR protein CTD PMID:17555550 , PMID:28374803 rottlerin multiple interactions EXP 6480464 rottlerin inhibits the reaction [irinotecan metabolite results in increased phosphorylation of EGFR protein] more ... CTD PMID:15177934 , PMID:15723263 rutin multiple interactions EXP 6480464 Rutin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 scopolamine decreases expression ISO RGD:2543 6480464 Scopolamine results in decreased expression of EGFR mRNA CTD PMID:12818353 selenium atom decreases expression EXP 6480464 Selenium results in decreased expression of EGFR mRNA CTD PMID:17390030 selenomethionine increases expression EXP 6480464 Selenomethionine results in increased expression of EGFR mRNA CTD PMID:17205524 serpentine asbestos decreases phosphorylation EXP 6480464 Asbestos, Serpentine results in decreased phosphorylation of EGFR protein CTD PMID:15626777 serpentine asbestos multiple interactions ISO RGD:10511 6480464 N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos, Serpentine results in increased activity of EGFR protein] CTD PMID:16571779 serpentine asbestos increases activity ISO RGD:10511 6480464 Asbestos, Serpentine results in increased activity of EGFR protein CTD PMID:16571779 sertraline increases expression EXP 6480464 Sertraline results in increased expression of EGFR mRNA CTD PMID:24865413 silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of EGFR mRNA, Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:21540303 more ... silicon dioxide increases phosphorylation EXP 6480464 Silicon Dioxide analog results in increased phosphorylation of EGFR protein CTD PMID:24844442 silicon dioxide increases expression ISO RGD:10511 6480464 Silicon Dioxide results in increased expression of EGFR mRNA CTD PMID:23221170 simvastatin multiple interactions ISO RGD:2543 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein]], Simvastatin inhibits the reaction [Acrolein results in increased phosphorylation of EGFR protein] CTD PMID:20359552 sirolimus multiple interactions ISO RGD:10511 6480464 [Sirolimus results in increased phosphorylation of and results in increased activity of EGFR protein] which results in increased phosphorylation of MAPK1 protein more ... CTD PMID:19151764 sirolimus multiple interactions EXP 6480464 AG 1879 inhibits the reaction [Sirolimus results in increased phosphorylation of EGFR protein] CTD PMID:19151764 sodium arsenate increases expression ISO RGD:10511 6480464 sodium arsenate results in increased expression of EGFR mRNA CTD PMID:21795629 sodium arsenite multiple interactions EXP 6480464 [sodium arsenite results in increased expression of EGFR protein] which results in increased phosphorylation of PCNA protein more ... CTD PMID:11723127 more ... sodium arsenite decreases phosphorylation ISO RGD:2543 6480464 sodium arsenite results in decreased phosphorylation of EGFR protein CTD PMID:29228391 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of EGFR mRNA CTD PMID:28595984 sodium arsenite affects methylation EXP 6480464 sodium arsenite affects the methylation of EGFR gene CTD PMID:28589171 sodium arsenite increases activity EXP 6480464 sodium arsenite results in increased activity of EGFR protein CTD PMID:19414066 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of EGFR mRNA, sodium arsenite results in increased expression of EGFR protein CTD PMID:12016162 , PMID:25907674 sodium arsenite increases phosphorylation ISO RGD:2543 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:9710602 sodium arsenite multiple interactions ISO RGD:2543 6480464 [EGF protein results in decreased expression of EGFR protein] inhibits the reaction [sodium arsenite results in increased activity of MAPK1 protein] more ... CTD PMID:29228391 , PMID:9710602 sodium arsenite increases expression ISO RGD:10511 6480464 sodium arsenite results in increased expression of EGFR mRNA CTD PMID:17077188 , PMID:9846968 sodium arsenite multiple interactions ISO RGD:10511 6480464 sodium arsenite promotes the reaction [SRC protein binds to EGFR protein], sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein CTD PMID:11723127 sodium arsenite decreases expression ISO RGD:10511 6480464 sodium arsenite results in decreased expression of EGFR mRNA, sodium arsenite results in decreased expression of EGFR protein CTD PMID:16507464 , PMID:19822182 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of EGFR protein CTD PMID:10564177 more ... sodium arsenite affects expression ISO RGD:10511 6480464 sodium arsenite affects the expression of EGFR mRNA CTD PMID:16507464 sodium chloride increases phosphorylation ISO RGD:10511 6480464 Sodium Chloride results in increased phosphorylation of EGFR protein CTD PMID:21568938 sodium chloride multiple interactions ISO RGD:10511 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] more ... CTD PMID:21568938 sodium hydroxide affects response to substance EXP 6480464 EGFR SNP affects the susceptibility to Sodium Hydroxide CTD PMID:27206134 sorafenib decreases expression EXP 6480464 sorafenib results in decreased expression of EGFR mRNA CTD PMID:26409325 sphingosine 1-phosphate increases phosphorylation EXP 6480464 sphingosine 1-phosphate results in increased phosphorylation of EGFR protein CTD PMID:26518876 sphingosine 1-phosphate multiple interactions EXP 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased phosphorylation of EGFR protein] CTD PMID:26518876 staurosporine multiple interactions EXP 6480464 Staurosporine inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 stilbenoid multiple interactions EXP 6480464 Stilbenes analog results in decreased expression of and results in decreased phosphorylation of EGFR protein CTD PMID:25063218 SU6656 multiple interactions EXP 6480464 SU 6656 inhibits the reaction [sodium arsenite results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15504454 SU6656 multiple interactions ISO RGD:10511 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein], [SU 6656 results in decreased activity of SRC protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:23376140 succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of EGFR mRNA CTD PMID:26378955 sulfasalazine multiple interactions EXP 6480464 [Sulfasalazine co-treated with tripterine] affects the expression of EGFR protein more ... CTD PMID:20007406 sulindac sulfide multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein], Chloroquine inhibits the reaction [sulindac sulfide results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfide decreases expression EXP 6480464 sulindac sulfide results in decreased expression of EGFR protein CTD PMID:20332299 sulindac sulfide increases ubiquitination EXP 6480464 sulindac sulfide results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfide increases phosphorylation EXP 6480464 sulindac sulfide results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfide decreases phosphorylation EXP 6480464 sulindac sulfide results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein], Chloroquine inhibits the reaction [sulindac sulfone results in decreased expression of EGFR protein] CTD PMID:20332299 sulindac sulfone increases ubiquitination EXP 6480464 sulindac sulfone results in increased ubiquitination of EGFR protein CTD PMID:20332299 sulindac sulfone multiple interactions ISO RGD:2543 6480464 [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein, [Celecoxib co-treated with sulindac sulfone] results in decreased expression of EGFR protein modified form CTD PMID:17908994 sulindac sulfone increases phosphorylation EXP 6480464 sulindac sulfone results in increased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases phosphorylation EXP 6480464 sulindac sulfone results in decreased phosphorylation of EGFR protein CTD PMID:20332299 sulindac sulfone decreases expression EXP 6480464 sulindac sulfone results in decreased expression of EGFR protein CTD PMID:20332299 Sulpyrine multiple interactions ISO RGD:2543 6480464 Dipyrone promotes the reaction [Hydrochloric Acid results in increased expression of EGFR protein] CTD PMID:15309881 sunitinib decreases expression EXP 6480464 Sunitinib results in decreased expression of EGFR mRNA CTD PMID:31533062 suramin multiple interactions ISO RGD:2543 6480464 Suramin inhibits the reaction [sodium arsenite results in increased phosphorylation of EGFR protein] CTD PMID:9710602 tamoxifen decreases response to substance EXP 6480464 EGFR protein results in decreased susceptibility to Tamoxifen CTD PMID:15665275 , PMID:16000581 tamoxifen affects expression ISO RGD:10511 6480464 Tamoxifen affects the expression of EGFR mRNA CTD PMID:17555576 tamoxifen increases expression EXP 6480464 Tamoxifen results in increased expression of EGFR mRNA, Tamoxifen results in increased expression of EGFR protein CTD PMID:20005069 tamoxifen multiple interactions EXP 6480464 [EGF protein results in increased activity of EGFR protein] which results in decreased susceptibility to Tamoxifen more ... CTD PMID:19347870 , PMID:24758408 tanespimycin decreases expression EXP 6480464 tanespimycin results in decreased expression of EGFR protein CTD PMID:17010675 tanespimycin multiple interactions EXP 6480464 tanespimycin results in increased degradation of and results in decreased expression of EGFR protein CTD PMID:16061882 taurocholic acid increases phosphorylation EXP 6480464 Taurocholic Acid results in increased phosphorylation of EGFR protein CTD PMID:26518876 taurocholic acid multiple interactions EXP 6480464 JTE 013 inhibits the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein], S1PR2 mRNA promotes the reaction [Taurocholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:26518876 Terfenadine multiple interactions EXP 6480464 11 more ... CTD PMID:19289568 Terfenadine decreases phosphorylation EXP 6480464 Terfenadine analog results in decreased phosphorylation of EGFR protein CTD PMID:19289568 teriflunomide multiple interactions EXP 6480464 teriflunomide inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:30364229 testosterone multiple interactions ISO RGD:2543 6480464 [Methylnitrosourea co-treated with Testosterone] results in increased expression of and results in increased phosphorylation of EGFR protein more ... CTD PMID:17272394 more ... testosterone increases phosphorylation ISO RGD:2543 6480464 Testosterone results in increased phosphorylation of EGFR protein CTD PMID:21177760 testosterone increases expression EXP 6480464 Testosterone results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone multiple interactions EXP 6480464 [Testosterone co-treated with Calcitriol] results in increased expression of EGFR mRNA CTD PMID:21592394 testosterone increases expression ISO RGD:10511 6480464 Testosterone results in increased expression of EGFR mRNA CTD PMID:21669218 tetrachloromethane multiple interactions ISO RGD:2543 6480464 [Diethylnitrosamine co-treated with Carbon Tetrachloride] results in increased phosphorylation of EGFR protein more ... CTD PMID:18006644 , PMID:29923357 tetrachloromethane decreases expression ISO RGD:10511 6480464 Carbon Tetrachloride results in decreased expression of EGFR mRNA CTD PMID:29987408 tetrachloromethane increases expression ISO RGD:10511 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA, Carbon Tetrachloride results in increased expression of EGFR protein CTD PMID:17484886 , PMID:27477297 tetrachloromethane multiple interactions ISO RGD:10511 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetrachloromethane increases expression ISO RGD:2543 6480464 Carbon Tetrachloride results in increased expression of EGFR mRNA CTD PMID:16644059 , PMID:18006644 tetracycline decreases expression ISO RGD:10511 6480464 Tetracycline results in decreased expression of EGFR mRNA CTD PMID:24489787 tetramethylpyrazine multiple interactions ISO RGD:10511 6480464 NFE2L2 protein promotes the reaction [tetramethylpyrazine inhibits the reaction [Carbon Tetrachloride results in increased expression of EGFR mRNA]] more ... CTD PMID:27477297 tetraphene multiple interactions ISO RGD:10511 6480464 AHR protein affects the reaction [benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein]], benz(a)anthracene inhibits the reaction [EGF protein binds to EGFR protein] CTD PMID:6309801 tetrathiomolybdate(2-) multiple interactions EXP 6480464 tetrathiomolybdate inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein] CTD PMID:18480265 thapsigargin increases expression ISO RGD:10511 6480464 Thapsigargin results in increased expression of EGFR protein CTD PMID:24648495 theaflavin multiple interactions ISO RGD:10511 6480464 theaflavin inhibits the reaction [Diethylnitrosamine results in increased expression of EGFR mRNA] CTD PMID:27058323 thioacetamide decreases expression ISO RGD:2543 6480464 Thioacetamide results in decreased expression of EGFR mRNA CTD PMID:23411599 thioacetamide multiple interactions ISO RGD:2543 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of EGFR mRNA CTD PMID:28943392 toluene 2,4-diisocyanate multiple interactions EXP 6480464 EGFR protein affects the reaction [[Toluene 2 more ... CTD PMID:16908450 topotecan multiple interactions ISO RGD:2543 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EGFR mRNA CTD PMID:25729387 topotecan decreases expression ISO RGD:10511 6480464 Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 topotecan multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] which results in decreased susceptibility to Topotecan CTD PMID:15923621 topotecan decreases phosphorylation EXP 6480464 Topotecan results in decreased phosphorylation of EGFR protein CTD PMID:15923621 topotecan decreases expression EXP 6480464 Topotecan results in decreased expression of EGFR mRNA, Topotecan results in decreased expression of EGFR protein CTD PMID:15923621 torin 1 multiple interactions EXP 6480464 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo(h)(1 more ... CTD PMID:26455392 trans-piceid multiple interactions EXP 6480464 polydatin inhibits the reaction [TGFA protein affects the localization of EGFR protein] CTD PMID:21967610 triamterene affects response to substance EXP 6480464 EGFR gene SNP affects the susceptibility to Triamterene CTD PMID:25622337 trichloroethene decreases expression ISO RGD:10511 6480464 Trichloroethylene results in decreased expression of EGFR mRNA CTD PMID:15363585 more ... trichloroethene increases methylation ISO RGD:2543 6480464 Trichloroethylene results in increased methylation of EGFR gene CTD PMID:27618143 trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of EGFR mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP 6480464 Atropine inhibits the reaction [Parathion results in increased expression of EGFR protein] CTD PMID:17390078 trovafloxacin multiple interactions ISO RGD:10511 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of EGFR mRNA CTD PMID:18930950 tyrphostin AG 1478 multiple interactions EXP 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of FOXO3 protein] more ... CTD PMID:15177934 more ... tyrphostin AG 1478 decreases expression EXP 6480464 RTKI cpd results in decreased expression of EGFR protein modified form CTD PMID:29974605 tyrphostin AG 1478 decreases phosphorylation EXP 6480464 RTKI cpd results in decreased phosphorylation of EGFR protein CTD PMID:15923621 more ... tyrphostin AG 1478 decreases activity EXP 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:27071941 tyrphostin AG 1478 decreases activity ISO RGD:2543 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:15574683 tyrphostin AG 1478 multiple interactions ISO RGD:2543 6480464 [RTKI cpd results in decreased activity of EGFR protein] inhibits the reaction [Genistein results in increased secretion of Testosterone] more ... CTD PMID:15459120 more ... tyrphostin AG 1478 decreases activity ISO RGD:10511 6480464 RTKI cpd results in decreased activity of EGFR protein CTD PMID:12794006 tyrphostin AG 1478 multiple interactions ISO RGD:10511 6480464 [[RTKI cpd results in decreased activity of EGFR protein] co-treated with [SU 6656 results in decreased activity of SRC protein]] inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of STAT3 protein] more ... CTD PMID:18758753 more ... U-73122 multiple interactions EXP 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:15177934 urethane multiple interactions ISO RGD:10511 6480464 [Urethane co-treated with Freund's Adjuvant] results in increased expression of EGFR mRNA, IFNG protein promotes the reaction [Urethane results in increased expression of EGFR mRNA] CTD PMID:12400877 , PMID:12810352 urethane decreases expression EXP 6480464 Urethane results in decreased expression of EGFR mRNA CTD PMID:28818685 urethane increases expression ISO RGD:10511 6480464 Urethane results in increased expression of EGFR mRNA CTD PMID:12400877 ursodeoxycholic acid multiple interactions EXP 6480464 Ursodeoxycholic Acid inhibits the reaction [Deoxycholic Acid results in increased phosphorylation of EGFR protein] CTD PMID:14747693 ursolic acid multiple interactions ISO RGD:10511 6480464 resveratrol promotes the reaction [ursolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of EGFR]] more ... CTD PMID:26100520 UTP increases phosphorylation ISO RGD:2543 6480464 Uridine Triphosphate results in increased phosphorylation of EGFR protein CTD PMID:14676212 valdecoxib decreases expression ISO RGD:2543 6480464 valdecoxib results in decreased expression of EGFR mRNA CTD PMID:24136188 valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of EGFR gene CTD PMID:29154799 valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EGFR mRNA CTD PMID:27188386 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of EGFR mRNA CTD PMID:23179753 more ... valproic acid decreases expression ISO RGD:10511 6480464 Valproic Acid results in decreased expression of EGFR mRNA CTD PMID:24535564 vanadyl sulfate increases phosphorylation EXP 6480464 vanadyl sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 , PMID:11943669 vandetanib affects response to substance EXP 6480464 EGFR affects the susceptibility to N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine CTD PMID:15604279 vandetanib decreases activity EXP 6480464 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in decreased activity of EGFR protein CTD PMID:15596048 vandetanib decreases phosphorylation EXP 6480464 N-(4-bromo-2-fluorophenyl)-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazolin-4-amine results in decreased phosphorylation of EGFR protein CTD PMID:21350000 veliparib decreases response to substance EXP 6480464 EGFR protein results in decreased susceptibility to veliparib CTD PMID:21912620 veliparib affects localization EXP 6480464 veliparib affects the localization of EGFR protein CTD PMID:21719137 vinclozolin multiple interactions ISO RGD:2543 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of EGFR mRNA CTD PMID:25607892 vitamin E decreases expression EXP 6480464 Vitamin E results in decreased expression of EGFR mRNA CTD PMID:19244175 vorinostat decreases expression ISO RGD:2543 6480464 vorinostat results in decreased expression of EGFR mRNA, vorinostat results in decreased expression of EGFR protein CTD PMID:21389970 vorinostat decreases phosphorylation EXP 6480464 vorinostat results in decreased phosphorylation of EGFR protein CTD PMID:20531243 WIN 55212-2 increases phosphorylation EXP 6480464 Win 55212-2 results in increased phosphorylation of EGFR protein CTD PMID:20619260 WIN 55212-2 multiple interactions EXP 6480464 RTKI cpd inhibits the reaction [Win 55212-2 results in increased phosphorylation of EGFR protein] CTD PMID:20619260 wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [EGF protein results in increased phosphorylation of EGFR protein], wortmannin inhibits the reaction [NTS protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15177934 , PMID:25856345 wortmannin multiple interactions ISO RGD:10511 6480464 wortmannin inhibits the reaction [Sodium Chloride results in increased phosphorylation of EGFR protein] CTD PMID:21568938 zinc atom multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc atom increases phosphorylation ISO RGD:10511 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694 zinc atom increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc atom multiple interactions ISO RGD:10511 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 zinc atom decreases expression ISO RGD:2543 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc dichloride increases phosphorylation EXP 6480464 zinc chloride results in increased phosphorylation of EGFR protein CTD PMID:21540303 zinc sulfate multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:16410015 zinc sulfate increases phosphorylation ISO RGD:2543 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:19946718 zinc sulfate increases phosphorylation EXP 6480464 Zinc Sulfate results in increased phosphorylation of EGFR protein CTD PMID:10564177 , PMID:11943669 zinc(0) multiple interactions EXP 6480464 4-((3-bromophenyl)amino)-6 more ... CTD PMID:12915106 more ... zinc(0) decreases expression ISO RGD:2543 6480464 Zinc deficiency results in decreased expression of EGFR mRNA CTD PMID:12672911 zinc(0) multiple interactions ISO RGD:10511 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:11983694 zinc(0) increases phosphorylation EXP 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:12915106 more ... zinc(0) increases phosphorylation ISO RGD:10511 6480464 Zinc results in increased phosphorylation of EGFR protein CTD PMID:11983694
Biological Process activation of MAPKK activity IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 activation of phospholipase A2 activity by calcium-mediated signaling TAS 2290271 (PMID:12435727) UniProtKB PMID:12435727 activation of phospholipase C activity TAS 2290271 (PMID:12435727) UniProtKB PMID:12435727 astrocyte activation IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 cell differentiation IBA PANTHER:PTN002814603 , RGD:2543 2290271 (PMID:21873635) GO_Central PMID:21873635 cell surface receptor signaling pathway IDA 2290271 (PMID:7736574) MGI PMID:7736574 cell-cell adhesion IMP 2290271 (PMID:12435727) UniProtKB PMID:12435727 cellular response to amino acid stimulus IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 cellular response to cadmium ion IMP 2290271 (PMID:26514923) CAFA PMID:26514923 cellular response to dexamethasone stimulus IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 cellular response to epidermal growth factor stimulus ISS UniProtKB:G3V6K6 2290271 UniProtKB GO_REF:0000024 cellular response to estradiol stimulus IDA 2290271 (PMID:20551055) UniProtKB PMID:20551055 cellular response to mechanical stimulus IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 cellular response to reactive oxygen species IMP 2290271 (PMID:26514923) CAFA PMID:26514923 cerebral cortex cell migration IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 circadian rhythm IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 digestive tract morphogenesis IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 diterpenoid metabolic process IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 embryonic placenta development IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 epidermal growth factor receptor signaling pathway IMP 2290271 (PMID:20878056) UniProtKB PMID:20878056 epidermal growth factor receptor signaling pathway TAS 2290271 Reactome Reactome:R-HSA-177929 epidermal growth factor receptor signaling pathway IDA 2290271 (PMID:12435727), (PMID:7736574) UniProtKB PMID:12435727 , PMID:7736574 ERBB2 signaling pathway TAS 2290271 Reactome Reactome:R-HSA-1227986 eyelid development in camera-type eye IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 hair follicle development IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 hair follicle development IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 hydrogen peroxide metabolic process IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 learning or memory ISS UniProtKB:G3V6K6 2290271 UniProtKB GO_REF:0000024 liver regeneration IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 lung development IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 magnesium ion homeostasis IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 MAPK cascade TAS 2290271 Reactome Reactome:R-HSA-5673001 membrane organization TAS 2290271 Reactome Reactome:R-HSA-199991 midgut development IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 morphogenesis of an epithelial fold IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 multicellular organism development IBA FB:FBgn0003733 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 negative regulation of apoptotic process IMP 2290271 (PMID:18070883) UniProtKB PMID:18070883 negative regulation of apoptotic process IBA PANTHER:PTN002814603 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 negative regulation of cardiocyte differentiation IMP 2290271 (PMID:23069713) BHF-UCL PMID:23069713 negative regulation of epidermal growth factor receptor signaling pathway TAS 2290271 Reactome Reactome:R-HSA-182971 negative regulation of ERBB signaling pathway TAS 2290271 Reactome Reactome:R-HSA-8864125 negative regulation of mitotic cell cycle IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 negative regulation of Notch signaling pathway TAS 2290271 Reactome Reactome:R-HSA-9018572, Reactome:R-HSA-9018573 negative regulation of protein catabolic process IDA 2290271 (PMID:17115032) UniProtKB PMID:17115032 neuron projection morphogenesis IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 ossification NAS 2290271 (PMID:12925580) UniProtKB PMID:12925580 ovulation cycle IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 peptidyl-tyrosine autophosphorylation IMP 2290271 (PMID:20878056) UniProtKB PMID:20878056 peptidyl-tyrosine autophosphorylation TAS 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 peptidyl-tyrosine phosphorylation IEA GO:0004713 2290271 GOC GO_REF:0000108 peptidyl-tyrosine phosphorylation IDA 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 peptidyl-tyrosine phosphorylation IEA GO:0004714 2290271 GOC GO_REF:0000108 positive regulation of blood vessel diameter IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of bone resorption IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of canonical Wnt signaling pathway IMP 2290271 (PMID:20302655) BHF-UCL PMID:20302655 positive regulation of cell growth IDA 2290271 (PMID:15467833) UniProtKB PMID:15467833 positive regulation of cell migration IMP 2290271 (PMID:12435727), (PMID:25678558) UniProtKB PMID:12435727 , PMID:25678558 positive regulation of cell population proliferation IDA 2290271 (PMID:7736574) MGI PMID:7736574 positive regulation of cell population proliferation IMP 2290271 (PMID:27057632) BHF-UCL PMID:27057632 positive regulation of cell population proliferation IBA FB:FBgn0003731 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 positive regulation of cyclin-dependent protein serine/threonine kinase activity IMP 2290271 (PMID:18483258) BHF-UCL PMID:18483258 positive regulation of DNA repair IDA 2290271 (PMID:17115032) UniProtKB PMID:17115032 positive regulation of DNA replication IDA 2290271 (PMID:17115032) UniProtKB PMID:17115032 positive regulation of epithelial cell proliferation IDA 2290271 (PMID:10572067) UniProtKB PMID:10572067 positive regulation of epithelial cell proliferation IBA MGI:MGI:95294 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 positive regulation of ERK1 and ERK2 cascade IDA 2290271 (PMID:20551055) UniProtKB PMID:20551055 positive regulation of ERK1 and ERK2 cascade IMP 2290271 (PMID:21673316) BHF-UCL PMID:21673316 positive regulation of fibroblast proliferation IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 positive regulation of G1/S transition of mitotic cell cycle IMP 2290271 (PMID:18483258) BHF-UCL PMID:18483258 positive regulation of inflammatory response IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of kinase activity IBA PANTHER:PTN002356460 , UniProtKB:Q16832 2290271 (PMID:21873635) GO_Central PMID:21873635 positive regulation of MAP kinase activity IDA 2290271 (PMID:10572067) UniProtKB PMID:10572067 positive regulation of NIK/NF-kappaB signaling IMP 2290271 (PMID:26514923) CAFA PMID:26514923 positive regulation of nitric oxide mediated signal transduction IDA 2290271 (PMID:12828935) UniProtKB PMID:12828935 positive regulation of peptidyl-serine phosphorylation IMP 2290271 (PMID:20878056) UniProtKB PMID:20878056 positive regulation of phosphorylation IDA 2290271 (PMID:15082764) UniProtKB PMID:15082764 positive regulation of production of miRNAs involved in gene silencing by miRNA IMP 2290271 (PMID:21673316) BHF-UCL PMID:21673316 positive regulation of prolactin secretion IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of protein kinase B signaling IMP 2290271 (PMID:17655843) BHF-UCL PMID:17655843 positive regulation of protein kinase B signaling TAS 2290271 Reactome Reactome:R-HSA-2316434 positive regulation of protein kinase C activity IDA 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 positive regulation of protein localization to plasma membrane IDA 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 positive regulation of protein phosphorylation IDA 2290271 (PMID:20551055) UniProtKB PMID:20551055 positive regulation of smooth muscle cell proliferation IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of superoxide anion generation IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of synaptic transmission, glutamatergic IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 positive regulation of transcription by RNA polymerase II IDA 2290271 (PMID:20551055) UniProtKB PMID:20551055 positive regulation of transcription, DNA-templated IMP 2290271 (PMID:26514923) CAFA PMID:26514923 positive regulation of vasoconstriction IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 protein autophosphorylation IMP 2290271 (PMID:18070883) UniProtKB PMID:18070883 protein insertion into membrane TAS 2290271 (PMID:12435727) UniProtKB PMID:12435727 receptor-mediated endocytosis IDA 2290271 (PMID:16543144) CACAO PMID:16543144 regulation of cell motility TAS 2290271 Reactome Reactome:R-HSA-6785631 regulation of ERK1 and ERK2 cascade IMP 2290271 (PMID:26514923) CAFA PMID:26514923 regulation of JNK cascade IMP 2290271 (PMID:26514923) CAFA PMID:26514923 regulation of nitric-oxide synthase activity IDA 2290271 (PMID:12828935) UniProtKB PMID:12828935 regulation of peptidyl-tyrosine phosphorylation IMP 2290271 (PMID:12435727) UniProtKB PMID:12435727 regulation of phosphatidylinositol 3-kinase signaling IMP 2290271 (PMID:26514923) CAFA PMID:26514923 regulation of transcription by RNA polymerase II TAS 2290271 Reactome Reactome:R-HSA-8866910 response to calcium ion IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 response to cobalamin IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 response to hydroxyisoflavone IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 response to osmotic stress IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 response to UV-A IDA 2290271 (PMID:18483258) BHF-UCL PMID:18483258 salivary gland morphogenesis IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 signal transduction IDA 2290271 (PMID:10572067) UniProtKB PMID:10572067 signal transduction TAS 2290271 Reactome Reactome:R-HSA-212718 tongue development IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 translation IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 transmembrane receptor protein tyrosine kinase signaling pathway IEA InterPro:IPR006211 , InterPro:IPR016245 2290271 InterPro GO_REF:0000002 transmembrane receptor protein tyrosine kinase signaling pathway IBA FB:FBgn0003366 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 transmembrane receptor protein tyrosine kinase signaling pathway IEA InterPro:IPR006211 2290271 InterPro GO_REF:0000002 viral entry into host cell IEA GO:0001618 2290271 GOC GO_REF:0000108 wound healing IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 Cellular Component apical plasma membrane IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 basal plasma membrane IBA PANTHER:PTN000698827 , RGD:2561 2290271 (PMID:21873635) GO_Central PMID:21873635 basolateral plasma membrane IDA 2290271 (PMID:12646923) BHF-UCL PMID:12646923 cell junction IDA 2290271 HPA GO_REF:0000052 cell surface IDA 2290271 (PMID:25666625) UniProtKB PMID:25666625 clathrin-coated vesicle membrane TAS 2290271 Reactome Reactome:R-HSA-8868658 more ... cytoplasm IDA 2290271 (PMID:12435727), (PMID:22298428), (PMID:7588596) UniProt PMID:12435727 more ... early endosome membrane IDA 2290271 (PMID:17714434) UniProtKB PMID:17714434 endocytic vesicle IEA UniProtKB:Q01279 , ensembl:ENSMUSP000000203292290271 Ensembl GO_REF:0000107 endocytic vesicle IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 endoplasmic reticulum membrane IEA UniProtKB-SubCell:SL-0097 2290271 UniProt GO_REF:0000044 endosome IDA 2290271 (PMID:14702346), (PMID:17182860), (PMID:22732145) UniProtKB PMID:14702346 more ... endosome colocalizes_with IDA 2290271 (PMID:16554368) ParkinsonsUK-UCL PMID:16554368 endosome membrane IDA 2290271 (PMID:22719997) UniProtKB PMID:22719997 extracellular space NAS 2290271 (PMID:9103388) UniProtKB PMID:9103388 focal adhesion HDA 2290271 (PMID:21423176) UniProtKB PMID:21423176 Golgi membrane IEA UniProtKB-SubCell:SL-0134 2290271 UniProt GO_REF:0000044 integral component of membrane IEA UniProtKB-KW:KW-0812 2290271 UniProt GO_REF:0000043 integral component of plasma membrane IBA FB:FBgn0003366 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 membrane IDA 2290271 (PMID:12435727) UniProtKB PMID:12435727 membrane raft IDA 2290271 (PMID:12009895) UniProtKB PMID:12009895 membrane raft ISS UniProtKB:F1N7F3 2290271 ARUK-UCL GO_REF:0000024 multivesicular body, internal vesicle lumen IDA 2290271 (PMID:17714434) UniProtKB PMID:17714434 nuclear membrane IEA UniProtKB-SubCell:SL-0182 2290271 UniProt GO_REF:0000044 nucleus IDA 2290271 (PMID:12828935), (PMID:17115032), (PMID:20551055) UniProtKB PMID:12828935 more ... perinuclear region of cytoplasm IMP 2290271 (PMID:24854121) ARUK-UCL PMID:24854121 plasma membrane TAS 2290271 Reactome Reactome:R-HSA-1169421 more ... plasma membrane IDA 2290271 (PMID:15465819), (PMID:20462955), (PMID:22298428), (PMID:22732145) HGNC-UCL GO_REF:0000052 more ... protein-containing complex IDA 2290271 (PMID:20878056) UniProtKB PMID:20878056 receptor complex IDA 2290271 (PMID:23382219) MGI PMID:23382219 receptor complex IBA FB:FBgn0015380 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 Shc-EGFR complex ISS UniProtKB:Q9QX70 2290271 BHF-UCL GO_REF:0000024 synapse IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 Molecular Function actin filament binding IDA 2290271 (PMID:14702346) UniProtKB PMID:14702346 ATP binding IEA InterPro:IPR006211 2290271 InterPro GO_REF:0000002 ATP binding IEA UniProtKB-KW:KW-0067 2290271 UniProt GO_REF:0000043 ATPase binding ISS UniProtKB:F1N7F3 2290271 ARUK-UCL GO_REF:0000024 cadherin binding HDA 2290271 (PMID:25468996) BHF-UCL PMID:25468996 calmodulin binding IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 chromatin binding IDA 2290271 (PMID:20551055) UniProtKB PMID:20551055 double-stranded DNA binding NAS 2290271 (PMID:6325948) UniProtKB PMID:6325948 enzyme binding IPI UniProtKB:O15162 2290271 (PMID:12009895) UniProtKB PMID:12009895 epidermal growth factor binding IBA MGI:MGI:95294 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 epidermal growth factor-activated receptor activity IDA 2290271 (PMID:12435727), (PMID:17115032) UniProtKB PMID:12435727 , PMID:17115032 epidermal growth factor-activated receptor activity IBA MGI:MGI:95294 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 epidermal growth factor-activated receptor activity IMP 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 epidermal growth factor-activated receptor activity NAS 2290271 (PMID:2790960), (PMID:6325948) UniProtKB PMID:2790960 , PMID:6325948 identical protein binding IPI UniProtKB:P00533 2290271 (PMID:16777603), (PMID:17148612), (PMID:18042729), (PMID:19563760), (PMID:19650109), (PMID:20007378), (PMID:20029029), (PMID:20359299), (PMID:21278786), (PMID:21480528), (PMID:21482778), (PMID:22232519), (PMID:22579287), (PMID:23273428), (PMID:23374349), (PMID:23436906), (PMID:23636329), (PMID:24135280), (PMID:31980649) IntAct PMID:16777603 more ... integrin binding IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 MAP kinase kinase kinase activity NAS 2290271 (PMID:15542601) UniProtKB PMID:15542601 nitric-oxide synthase regulator activity contributes_to IDA 2290271 (PMID:12828935) UniProtKB PMID:12828935 protein binding IPI UniProtKB:Q96BE0 2290271 (PMID:25036637) IntAct PMID:25036637 protein binding IPI UniProtKB:Q9HD43 2290271 (PMID:28065597) IntAct PMID:28065597 protein binding IPI UniProtKB:P35813 2290271 (PMID:28065597) IntAct PMID:28065597 protein binding IPI UniProtKB:Q06124 2290271 (PMID:16273093), (PMID:28065597) IntAct PMID:16273093 , PMID:28065597 protein binding IPI UniProtKB:O75420 more ... 2290271 (PMID:20878056) UniProt PMID:20878056 protein binding IPI UniProtKB:Q9Y6Q6-2 2290271 (PMID:29844572) IntAct PMID:29844572 protein binding IPI UniProtKB:P42224 2290271 (PMID:12070153), (PMID:24658140), (PMID:31980649) IntAct PMID:12070153 more ... protein binding IPI UniProtKB:P42684 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P42229 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P23528 2290271 (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:P00519 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P12830 2290271 (PMID:24189400), (PMID:24658140), (PMID:25241761), (PMID:31980649) IntAct PMID:24189400 more ... protein binding IPI UniProtKB:Q14318 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:P08238 2290271 (PMID:15657067), (PMID:20029029), (PMID:22939624), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q14247 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:O00264 2290271 (PMID:26988023) UniProt PMID:26988023 protein binding IPI UniProtKB:P16885 2290271 (PMID:16273093), (PMID:24658140), (PMID:25241761), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P07900 2290271 (PMID:20029029), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:Q96CW1 2290271 (PMID:20029029), (PMID:24189400), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:Q92870 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P12931 2290271 (PMID:17284441), (PMID:20624308), (PMID:20935677), (PMID:21278788), (PMID:24658140), (PMID:28065597), (PMID:31980649) IntAct PMID:17284441 more ... protein binding IPI UniProtKB:P31948 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:Q13239 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P07948 2290271 (PMID:16799092), (PMID:23764002), (PMID:23866081), (PMID:24658140), (PMID:31980649) IntAct PMID:16799092 more ... protein binding IPI UniProtKB:O00459 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:Q13480 2290271 (PMID:21278788), (PMID:24658140), (PMID:31980649) IntAct PMID:21278788 more ... protein binding IPI UniProtKB:P16234 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q99075 2290271 (PMID:9135143) IntAct PMID:9135143 protein binding IPI UniProtKB:P01133 2290271 (PMID:12297050), (PMID:12620237), (PMID:17697999), (PMID:21439278), (PMID:21822280), (PMID:23597562), (PMID:25241761), (PMID:26280537), (PMID:2790960), (PMID:30083275), (PMID:9135143) IntAct PMID:12297050 more ... protein binding IPI UniProtKB:P23470 2290271 (PMID:25970784), (PMID:31980649) IntAct PMID:25970784 , PMID:31980649 protein binding IPI UniProtKB:Q9Y2H9 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:Q03135 2290271 (PMID:15657067), (PMID:16799092), (PMID:22411794), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P15941 2290271 (PMID:21258405), (PMID:24658140), (PMID:31980649) IntAct PMID:21258405 more ... protein binding IPI UniProtKB:Q02952 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:P31947 2290271 (PMID:15657067), (PMID:16799092), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P23467 2290271 (PMID:19167335), (PMID:28065597), (PMID:31980649) IntAct PMID:19167335 more ... protein binding IPI UniProtKB:Q13322 2290271 (PMID:24658140), (PMID:31980649), (PMID:9506989) IntAct PMID:24658140 more ... protein binding IPI UniProtKB:P63104 2290271 (PMID:15225635), (PMID:15657067), (PMID:24658140), (PMID:31980649) IntAct PMID:15225635 more ... protein binding IPI UniProtKB:Q13094 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P11142 2290271 (PMID:15657067), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q12933 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q12929 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q05397 2290271 (PMID:15657067), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P43403 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P34932 2290271 (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:P62993 2290271 (PMID:10026169), (PMID:10229072), (PMID:11896612), (PMID:12577067), (PMID:14679214), (PMID:15657067), (PMID:16273093), (PMID:16799092), (PMID:21278786), (PMID:21278788), (PMID:21706016), (PMID:23178716), (PMID:23799367), (PMID:24189400), (PMID:24658140), (PMID:27059931), (PMID:31585087), (PMID:31980649), (PMID:7518560), (PMID:8887653), (PMID:8940013), (PMID:9020117) IntAct PMID:10026169 more ... protein binding IPI UniProtKB:P29353 2290271 (PMID:15657067), (PMID:16273093), (PMID:20935677), (PMID:21278788), (PMID:23178716), (PMID:23799367), (PMID:24189400), (PMID:26551075), (PMID:28065597), (PMID:31585087), (PMID:31980649), (PMID:7518560), (PMID:7542744), (PMID:8034616), (PMID:9544989) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:O43561 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:O75791 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q9P0L0 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:Q68CZ2 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q71U36 2290271 (PMID:15657067), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P51636 2290271 (PMID:16799092), (PMID:24658140), (PMID:31980649) IntAct PMID:16799092 more ... protein binding IPI UniProtKB:P18433 2290271 (PMID:28065597), (PMID:31980649) IntAct PMID:28065597 , PMID:31980649 protein binding IPI UniProtKB:P26447 2290271 (PMID:24658140), (PMID:30083275), (PMID:31980649) IntAct PMID:24658140 more ... protein binding IPI UniProtKB:P09936 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:P38646 2290271 (PMID:15657067), (PMID:20029029), (PMID:24189400), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:O60716 2290271 (PMID:15657067), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q13387 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P51451 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:Q9UQB8 2290271 (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:24189400 more ... protein binding IPI UniProtKB:Q9UNE7 2290271 (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:P18031 2290271 (PMID:24658140), (PMID:25796184), (PMID:31980649), (PMID:9050838), (PMID:9355745) IntAct PMID:24658140 more ... protein binding IPI UniProtKB:Q05209 2290271 (PMID:20029029), (PMID:21376233), (PMID:24658140), (PMID:28065597), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:Q9Y2R2 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P60520 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:O60603 2290271 (PMID:17126326), (PMID:24658140), (PMID:31980649) IntAct PMID:17126326 more ... protein binding IPI UniProtKB:Q92731 2290271 (PMID:21951318) IntAct PMID:21951318 protein binding IPI UniProtKB:Q9QZC5 2290271 (PMID:31585087) IntAct PMID:31585087 protein binding IPI UniProtKB:O00170 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:P08631 2290271 (PMID:23397142), (PMID:24658140), (PMID:31980649) IntAct PMID:23397142 more ... protein binding IPI UniProtKB:P40763 2290271 (PMID:14966128), (PMID:15657067), (PMID:24135280), (PMID:24189400), (PMID:24658140), (PMID:25241761), (PMID:31980649) IntAct PMID:14966128 more ... protein binding IPI UniProtKB:P10599 2290271 (PMID:15657067), (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P08575 2290271 (PMID:19167335), (PMID:31980649) IntAct PMID:19167335 , PMID:31980649 protein binding IPI UniProtKB:Q8WUI4 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P04083 2290271 (PMID:20029029), (PMID:24189400), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:Q16543 2290271 (PMID:24189400), (PMID:25036637), (PMID:31980649) IntAct PMID:24189400 more ... protein binding IPI UniProtKB:Q6S5L8 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P04406 2290271 (PMID:16799092), (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:16799092 more ... protein binding IPI UniProtKB:Q8IZ07 2290271 (PMID:22298428) UniProt PMID:22298428 protein binding IPI UniProtKB:Q6ZTN6 2290271 (PMID:22298428) UniProt PMID:22298428 protein binding IPI UniProtKB:Q86YJ7 2290271 (PMID:22298428) UniProt PMID:22298428 protein binding IPI UniProtKB:Q9BRG2 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q09666 2290271 (PMID:20029029), (PMID:24189400), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:P49069 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:Q12852 2290271 (PMID:20029029), (PMID:31980649) IntAct PMID:20029029 , PMID:31980649 protein binding IPI UniProtKB:P22681 2290271 (PMID:15657067), (PMID:15962011), (PMID:16914641), (PMID:18273061), (PMID:20308550), (PMID:20562913), (PMID:23799367), (PMID:27059931), (PMID:7657591) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P27986 2290271 (PMID:16273093), (PMID:25241761), (PMID:7797556) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P07355 2290271 (PMID:25136068) AgBase PMID:25136068 protein binding IPI UniProtKB:P01135 2290271 (PMID:12297049), (PMID:24658140), (PMID:31980649) IntAct PMID:12297049 more ... protein binding IPI UniProtKB:P09769 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P16333 2290271 (PMID:10026169), (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:10026169 more ... protein binding IPI UniProtKB:Q9UQC2 2290271 (PMID:16253990), (PMID:19172738), (PMID:31585087) UniProt PMID:16253990 more ... protein binding IPI UniProtKB:P17252 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:O00750 2290271 (PMID:10805725), (PMID:24658140), (PMID:31980649) IntAct PMID:10805725 more ... protein binding IPI UniProtKB:P27348 2290271 (PMID:15657067), (PMID:20029029), (PMID:24189400), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:P46934 2290271 (PMID:29455656) IntAct PMID:29455656 protein binding IPI UniProtKB:Q99962 2290271 (PMID:24854121) ARUK-UCL PMID:24854121 protein binding IPI UniProtKB:Q9UBN7 2290271 (PMID:20029029), (PMID:24658140), (PMID:31980649) IntAct PMID:20029029 more ... protein binding IPI UniProtKB:Q9NSE2 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:Q9NRF2 2290271 (PMID:16273093), (PMID:24658140), (PMID:31585087), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P46108 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P04150 2290271 (PMID:24658140), (PMID:31980649) IntAct PMID:24658140 , PMID:31980649 protein binding IPI UniProtKB:P06493 2290271 (PMID:15657067), (PMID:24658140), (PMID:31980649) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q14956-1 2290271 (PMID:26751287) IntAct PMID:26751287 protein binding IPI UniProtKB:P52824 2290271 (PMID:22732145) ParkinsonsUK-UCL PMID:22732145 protein binding IPI UniProtKB:Q92569 2290271 (PMID:16273093), (PMID:24658140), (PMID:25241761), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:Q80U62 2290271 (PMID:25594178) IntAct PMID:25594178 protein binding IPI UniProtKB:Q96A65 2290271 (PMID:25594178) IntAct PMID:25594178 protein binding IPI UniProtKB:Q92625 2290271 (PMID:16273093), (PMID:24658140), (PMID:31980649) IntAct PMID:16273093 more ... protein binding IPI UniProtKB:P07947 2290271 (PMID:15657067), (PMID:23866081) IntAct PMID:15657067 , PMID:23866081 protein binding IPI UniProtKB:P04626 2290271 (PMID:10572067), (PMID:15657067), (PMID:16516204), (PMID:16843263), (PMID:17148612), (PMID:19650109), (PMID:21203579), (PMID:21278786), (PMID:23436906), (PMID:23866081), (PMID:24189400), (PMID:24557338), (PMID:25241761) IntAct PMID:10572067 more ... protein binding IPI UniProtKB:P20417 2290271 (PMID:7685104), (PMID:7693694), (PMID:8621392) IntAct PMID:7685104 more ... protein binding IPI UniProtKB:O75815 2290271 (PMID:18722344) UniProt PMID:18722344 protein binding IPI UniProtKB:P20936 2290271 (PMID:16273093), (PMID:2176151) IntAct PMID:16273093 , PMID:2176151 protein binding IPI UniProtKB:P19174 2290271 (PMID:14568990), (PMID:16273093), (PMID:7693694), (PMID:7993895), (PMID:9020117) IntAct PMID:14568990 more ... protein binding IPI UniProtKB:P04792 2290271 (PMID:15657067), (PMID:23397142), (PMID:24189400) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q92622 2290271 (PMID:24034250), (PMID:25594178) IntAct PMID:24034250 , PMID:25594178 protein binding IPI UniProtKB:P21860 2290271 (PMID:10572067), (PMID:17148612), (PMID:21278786), (PMID:22439932), (PMID:23436906), (PMID:23866081), (PMID:24189400) UniProtKB PMID:10572067 more ... protein binding IPI UniProtKB:P35221 2290271 (PMID:15657067), (PMID:24189400), (PMID:25241761) IntAct PMID:15657067 more ... protein binding IPI UniProtKB:Q9UJM3 2290271 (PMID:18046415), (PMID:18776048), (PMID:23273428), (PMID:24189400) UniProtKB PMID:18046415 more ... protein binding IPI UniProtKB:Q86VI4 2290271 (PMID:25594178), (PMID:28479384) IntAct PMID:25594178 , PMID:28479384 protein binding IPI UniProtKB:P08581 2290271 (PMID:20624308), (PMID:23866081), (PMID:24189400), (PMID:26551075) IntAct PMID:20624308 more ... protein binding IPI UniProtKB:P14174 2290271 (PMID:26280537) IntAct PMID:26280537 protein binding IPI UniProtKB:P46109 2290271 (PMID:23397142), (PMID:24658140), (PMID:31980649) IntAct PMID:23397142 more ... protein binding IPI UniProtKB:Q14956 2290271 (PMID:26751287) IntAct PMID:26751287 protein binding IPI UniProtKB:Q9UKV8 2290271 (PMID:23636329) IntAct PMID:23636329 protein binding IPI UniProtKB:P97313 2290271 (PMID:21266349) IntAct PMID:21266349 protein binding IPI UniProtKB:Q15109 2290271 (PMID:16954185) IntAct PMID:16954185 protein binding IPI UniProtKB:Q3V6T2 2290271 (PMID:20462955), (PMID:25187647) UniProt PMID:20462955 , PMID:25187647 protein binding IPI UniProtKB:Q96FE5 2290271 (PMID:17726113) IntAct PMID:17726113 protein binding IPI UniProtKB:P17936 2290271 (PMID:23178489) IntAct PMID:23178489 protein binding IPI UniProtKB:Q38SD2 2290271 (PMID:24947832) IntAct PMID:24947832 protein binding IPI UniProtKB:P07992 2290271 (PMID:24780295) IntAct PMID:24780295 protein binding IPI UniProtKB:P30530 2290271 (PMID:25873175) IntAct PMID:25873175 protein binding IPI UniProtKB:P07948-1 2290271 (PMID:23764002) IntAct PMID:23764002 protein binding IPI UniProtKB:Q9UKG1 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:O95704 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:O00213 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:Q9UQF2 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:O14944 2290271 (PMID:9419975) UniProtKB PMID:9419975 protein binding IPI UniProtKB:O75159 2290271 (PMID:15590694) UniProtKB PMID:15590694 protein binding IPI UniProtKB:P03372 2290271 (PMID:17284441) IntAct PMID:17284441 protein binding IPI UniProtKB:Q7Z7G1 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:Q6PKX4 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:P43405 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:P98077 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:Q99527 2290271 (PMID:20551055) UniProtKB PMID:20551055 protein binding IPI UniProtKB:P12004 2290271 (PMID:17115032) UniProtKB PMID:17115032 protein binding IPI UniProtKB:Q9UJ41 2290271 (PMID:16499958) IntAct PMID:16499958 protein binding IPI UniProtKB:Q8K424 2290271 (PMID:20403327) IntAct PMID:20403327 protein binding IPI UniProtKB:O75674 2290271 (PMID:19798056) IntAct PMID:19798056 protein binding IPI UniProtKB:P13866 2290271 (PMID:18455122) IntAct PMID:18455122 protein binding IPI UniProtKB:Q13671 2290271 (PMID:17403676) IntAct PMID:17403676 protein binding IPI UniProtKB:Q9UNH7 2290271 (PMID:11279102) HGNC PMID:11279102 protein binding IPI UniProtKB:Q01973 2290271 (PMID:22439932) IntAct PMID:22439932 protein binding IPI UniProtKB:Q9UQQ2 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:Q5T0W9 2290271 (PMID:23912460) UniProtKB PMID:23912460 protein binding IPI UniProtKB:P60468 2290271 (PMID:19602593) UniProtKB PMID:19602593 protein binding IPI UniProtKB:Q99700 2290271 (PMID:18602463) UniProtKB PMID:18602463 protein binding IPI UniProtKB:Q9H706 2290271 (PMID:19509291) UniProtKB PMID:19509291 protein binding IPI UniProtKB:Q9BZP6 2290271 (PMID:18824549) UniProtKB PMID:18824549 protein binding IPI UniProtKB:P05432 2290271 (PMID:17599051) UniProtKB PMID:17599051 protein binding IPI UniProtKB:O54967 2290271 (PMID:17182860) UniProtKB PMID:17182860 protein binding IPI UniProtKB:O95994 2290271 (PMID:25666625) UniProtKB PMID:25666625 protein binding IPI UniProtKB:P46940 2290271 (PMID:21349850) IntAct PMID:21349850 protein binding IPI UniProtKB:P03372-4 2290271 (PMID:20935677) IntAct PMID:20935677 protein binding IPI UniProtKB:Q9Y490 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:O14654 2290271 (PMID:16273093) IntAct PMID:16273093 protein binding IPI UniProtKB:Q15303 2290271 (PMID:10572067) UniProtKB PMID:10572067 protein binding IPI UniProtKB:P22682 2290271 (PMID:7657591) IntAct PMID:7657591 protein binding IPI UniProtKB:Q14457 2290271 (PMID:24034250) IntAct PMID:24034250 protein binding IPI UniProtKB:Q8NFJ5 2290271 (PMID:25311788) UniProtKB PMID:25311788 protein binding IPI UniProtKB:Q92600 2290271 (PMID:20878056) UniProtKB PMID:20878056 protein binding IPI UniProtKB:Q62384 2290271 (PMID:9852145) UniProtKB PMID:9852145 protein binding IPI UniProtKB:Q9Y2I7 2290271 (PMID:17909029) UniProtKB PMID:17909029 protein binding IPI UniProtKB:O43639 2290271 (PMID:10026169) UniProtKB PMID:10026169 protein binding IPI UniProtKB:Q8NBJ4 2290271 (PMID:27569582) IntAct PMID:27569582 protein binding IPI UniProtKB:P29355 2290271 (PMID:8305738) WormBase PMID:8305738 protein binding IPI UniProtKB:O14965 2290271 (PMID:23520446) IntAct PMID:23520446 protein binding IPI UniProtKB:P29353-7 2290271 (PMID:24658140) IntAct PMID:24658140 protein binding IPI UniProtKB:Q6PK50 2290271 (PMID:25036637) IntAct PMID:25036637 protein binding IPI UniProtKB:Q53FC7 2290271 (PMID:25036637) IntAct PMID:25036637 protein binding IPI UniProtKB:P46108-1 2290271 (PMID:24658140) IntAct PMID:24658140 protein binding IPI UniProtKB:Q70E73 2290271 (PMID:24076656) IntAct PMID:24076656 protein kinase binding IEA UniProtKB:G3V6K6 , ensembl:ENSRNOP000000060872290271 Ensembl GO_REF:0000107 protein phosphatase binding IPI UniProtKB:Q15262 2290271 (PMID:15899872) UniProtKB PMID:15899872 protein phosphatase binding IPI UniProtKB:P51452 2290271 (PMID:28759036) BHF-UCL PMID:28759036 protein tyrosine kinase activity IMP 2290271 (PMID:14702346), (PMID:20878056) UniProtKB PMID:14702346 , PMID:20878056 protein tyrosine kinase activity TAS 2290271 (PMID:16076471) UniProt PMID:16076471 more ... protein tyrosine kinase activity IDA 2290271 (PMID:17115032), (PMID:17599051) UniProtKB PMID:17115032 , PMID:17599051 transmembrane receptor protein tyrosine kinase activity IEA EC:2.7.10.1 2290271 UniProtKB GO_REF:0000003 transmembrane receptor protein tyrosine kinase activity IEA InterPro:IPR006211 2290271 InterPro GO_REF:0000002 transmembrane receptor protein tyrosine kinase activity TAS 2290271 Reactome Reactome:R-HSA-177933 transmembrane receptor protein tyrosine kinase activity IBA FB:FBgn0003366 more ... 2290271 (PMID:21873635) GO_Central PMID:21873635 transmembrane signaling receptor activity IDA 2290271 (PMID:7736574) MGI PMID:7736574 ubiquitin protein ligase binding IPI UniProtKB:Q9D0C1 2290271 (PMID:23418353) UniProtKB PMID:23418353 ubiquitin protein ligase binding IPI UniProtKB:Q91YL2 2290271 (PMID:23418353) UniProtKB PMID:23418353 virus receptor activity IEA UniProtKB-KW:KW-1183 2290271 UniProt GO_REF:0000043
Gene-Chemical Interaction Annotations