MMP7 (matrix metallopeptidase 7) - Rat Genome Database

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Gene: MMP7 (matrix metallopeptidase 7) Homo sapiens
Analyze
Symbol: MMP7
Name: matrix metallopeptidase 7
RGD ID: 736005
HGNC Page HGNC:7174
Description: Enables endopeptidase activity and metallopeptidase activity. Involved in positive regulation of cell migration and proteolysis. Acts upstream of or within membrane protein ectodomain proteolysis and membrane protein intracellular domain proteolysis. Located in extracellular exosome. Biomarker of endometrial cancer; endometrial hyperplasia; glioblastoma; and lung non-small cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: matrilysin; matrin; matrix metallopeptidase 7 (matrilysin, uterine); matrix metalloproteinase 7; matrix metalloproteinase 7 (matrilysin, uterine); matrix metalloproteinase-7; MMP-7; MPSL1; PUMP-1; pump-1 protease; uterine matrilysin; uterine metalloproteinase
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,520,508 - 102,530,747 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11102,520,508 - 102,530,750 (-)EnsemblGRCh38hg38GRCh38
GRCh3711102,391,239 - 102,401,478 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611101,896,449 - 101,906,688 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411101,896,448 - 101,906,688NCBI
Celera1199,552,782 - 99,563,021 (-)NCBICelera
Cytogenetic Map11q22.2NCBI
HuRef1198,318,241 - 98,328,480 (-)NCBIHuRef
CHM1_111102,274,287 - 102,284,528 (-)NCBICHM1_1
T2T-CHM13v2.011102,522,678 - 102,532,920 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
(E)-thiamethoxam  (ISO)
(S)-nicotine  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,7-dihydropurine-6-thione  (ISO)
3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid  (EXP)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (EXP)
aflatoxin B1  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
aluminium atom  (EXP)
aluminium(0)  (EXP)
ammonium chloride  (ISO)
andrographolide  (EXP)
antimonite  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
benzo[a]pyrene  (EXP)
benzyl isothiocyanate  (EXP)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
BQ 123  (EXP)
butyric acid  (ISO)
C.I. Natural Red 20  (EXP)
C60 fullerene  (ISO)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (EXP)
cannabidiol  (EXP)
carbon nanotube  (ISO)
celastrol  (ISO)
chlordecone  (ISO)
choline  (ISO)
chromium(6+)  (ISO)
cisplatin  (EXP)
clofibrate  (ISO)
clozapine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP,ISO)
curcumin  (EXP)
cyclosporin A  (EXP)
D-glucose  (ISO)
deguelin  (EXP)
delta-tocotrienol  (EXP)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diallyl disulfide  (EXP)
Diallyl sulfide  (EXP)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
diethylstilbestrol  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
ergosta-4,6,8(14),22-tetraen-3-one  (EXP,ISO)
ethanol  (ISO)
fenofibrate  (EXP)
ferric oxide  (EXP)
folic acid  (ISO)
fructose  (ISO)
furan  (ISO)
gallic acid  (EXP)
Garcinol  (EXP)
genistein  (EXP,ISO)
glucose  (ISO)
graphite  (ISO)
GW 4064  (ISO)
Honokiol  (ISO)
isoorientin  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (ISO)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
lithium chloride  (EXP)
losartan  (EXP,ISO)
mangiferin  (EXP)
mercaptopurine  (ISO)
methotrexate  (EXP)
mibolerone  (EXP)
mifepristone  (EXP)
N,N-diethyl-m-toluamide  (ISO)
N-acetyl-L-cysteine  (EXP)
niclosamide  (ISO)
nicotine  (EXP,ISO)
nitroglycerin  (EXP)
nobiletin  (EXP)
Pachymic acid  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP)
permethrin  (EXP,ISO)
phenethyl isothiocyanate  (EXP)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
pinosylvin  (EXP)
pioglitazone  (EXP,ISO)
pirinixic acid  (ISO)
procymidone  (ISO)
progesterone  (EXP,ISO)
propofol  (EXP)
Prothioconazole-desthio  (ISO)
pterostilbene  (ISO)
purine-6-thiol  (ISO)
quercetin  (EXP)
resveratrol  (EXP)
riddelliine  (ISO)
salicylates  (EXP)
serpentine asbestos  (EXP,ISO)
Shikonin  (EXP)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP,ISO)
sulindac  (ISO)
sulindac sulfone  (EXP)
Tanshinone I  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
thiamethoxam  (ISO)
thymoquinone  (EXP)
titanium dioxide  (EXP,ISO)
trans-pinosylvin  (EXP)
trichloroacetaldehyde  (ISO)
tyrphostin AG 1478  (EXP)
valproic acid  (EXP)
zearalenone  (ISO)
zinc dichloride  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Ischemia-modified albumin improves the usefulness of standard cardiac biomarkers for the diagnosis of myocardial ischemia in the emergency department setting. Anwaruddin S, etal., Am J Clin Pathol. 2005 Jan;123(1):140-5.
2. Prostate carcinomas developing in transgenic rats with SV40 T antigen expression under probasin promoter control are strictly androgen dependent. Asamoto M, etal., Cancer Res. 2001 Jun 15;61(12):4693-700.
3. Fibrosis of the left atria during progression of heart failure is associated with increased matrix metalloproteinases in the rat. Boixel C, etal., J Am Coll Cardiol. 2003 Jul 16;42(2):336-44.
4. Mechanism of matrix accumulation and glomerulosclerosis in spontaneously hypertensive rats. Camp TM, etal., J Hypertens 2003 Sep;21(9):1719-27.
5. Protease-activated receptor-1 antagonist F 16618 reduces arterial restenosis by down-regulation of tumor necrosis factor alpha and matrix metalloproteinase 7 expression, migration, and proliferation of vascular smooth muscle cells. Chieng-Yane P, etal., J Pharmacol Exp Ther. 2011 Mar;336(3):643-51. doi: 10.1124/jpet.110.175182. Epub 2010 Dec 7.
6. Role of myoglobin in the antioxidant defense of the heart. Flogel U, etal., FASEB J. 2004 Jul;18(10):1156-8. Epub 2004 May 7.
7. Modulation of extracellular matrix components by metalloproteinases and their tissue inhibitors during degeneration and regeneration of rat sural nerve. Gantus MA, etal., Brain Res. 2006 Nov 29;1122(1):36-46. Epub 2006 Oct 6.
8. Thyroid hormone stimulates myoglobin gene expression in rat cardiac muscle. Giannocco G, etal., Mol Cell Endocrinol. 2004 Oct 29;226(1-2):19-26.
9. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
10. Metalloproteinases and their associated genes contribute to the functional integrity and noise-induced damage in the cochlear sensory epithelium. Hu BH, etal., J Neurosci. 2012 Oct 24;32(43):14927-41. doi: 10.1523/JNEUROSCI.1588-12.2012.
11. Activation of adventitial fibroblasts in the early stage of the aortic transplant vasculopathy in rat. Ji J, etal., Transplantation. 2010 Apr 27;89(8):945-53. doi: 10.1097/TP.0b013e3181d05aa7.
12. Implication of matrix metalloproteinase 7 and the noncanonical wingless-type signaling pathway in a model of kidney allograft tolerance induced by the administration of anti-donor class II antibodies. Jovanovic V, etal., J Immunol. 2008 Feb 1;180(3):1317-25.
13. Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barre syndrome. Kieseier BC, etal., Ann Neurol. 1998 Apr;43(4):427-34.
14. Matrix metalloproteinase-9 and -7 are regulated in experimental autoimmune encephalomyelitis. Kieseier BC, etal., Brain. 1998 Jan;121 ( Pt 1):159-66.
15. Matrix metalloproteinase-7 affects connexin-43 levels, electrical conduction, and survival after myocardial infarction. Lindsey ML, etal., Circulation. 2006 Jun 27;113(25):2919-28. Epub 2006 Jun 12.
16. Immunolocalization and gene expression of matrilysin during corneal wound healing. Lu PC, etal., Invest Ophthalmol Vis Sci. 1999 Jan;40(1):20-7.
17. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL. Lynch CC, etal., Cancer Cell. 2005 May;7(5):485-96.
18. Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas. Nakano A, etal., J Neurosurg. 1995 Aug;83(2):298-307.
19. Significance of matrix metalloproteinase-7 [correction of matrix metalloproteinase-2], -11 and tissue inhibitor of metalloproteinase-1 expression in normal, hyperplastic and neoplastic endometrium. Obokata A, etal., Anticancer Res. 2007 Jan-Feb;27(1A):95-105.
20. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
21. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. The matrix metalloproteinase matrilysin influences early-stage mammary tumorigenesis. Rudolph-Owen LA, etal., Cancer Res. 1998 Dec 1;58(23):5500-6.
24. Expression of MMP-7, MMP-9, TIMP-1 and TIMP-2 mRNA in lung tissue of patients with non-small cell lung cancer (NSCLC) and benign pulmonary disease. Safranek J, etal., Anticancer Res. 2009 Jul;29(7):2513-7.
25. Rapamycin attenuates bladder hypertrophy during long-term outlet obstruction in vivo: tissue, matrix and mechanistic insights. Schroder A, etal., J Urol. 2013 Jun;189(6):2377-84. doi: 10.1016/j.juro.2012.12.110. Epub 2013 Jan 9.
26. Evaluation of coronary artery patency using cardiac markers. Tanasijevic MJ J Thromb Thrombolysis. 2005 Feb;19(1):21-4.
27. WNT/beta-catenin signaling is modulated by mechanical ventilation in an experimental model of acute lung injury. Villar J, etal., Intensive Care Med. 2011 Jul;37(7):1201-9. doi: 10.1007/s00134-011-2234-0. Epub 2011 May 13.
28. Activation of the Wnt/beta-catenin signaling pathway by mechanical ventilation is associated with ventilator-induced pulmonary fibrosis in healthy lungs. Villar J, etal., PLoS One. 2011;6(9):e23914. doi: 10.1371/journal.pone.0023914. Epub 2011 Sep 15.
29. Matrix metalloproteinase-7 and ADAM-12 (a disintegrin and metalloproteinase-12) define a signaling axis in agonist-induced hypertension and cardiac hypertrophy. Wang X, etal., Circulation. 2009 May 12;119(18):2480-9. doi: 10.1161/CIRCULATIONAHA.108.835488. Epub 2009 Apr 27.
30. [Defensin-5 and Matrilysin mRNA expression in the intestine of scalded rats and its relation to bacterial translocation]. Yang HM, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2004 Jun;16(6):345-7.
Additional References at PubMed
PMID:1497627   PMID:2253219   PMID:2550050   PMID:2844164   PMID:7694569   PMID:7756291   PMID:7896811   PMID:7980522   PMID:8125298   PMID:8216228   PMID:8294454   PMID:8786845  
PMID:8921407   PMID:8978768   PMID:9148753   PMID:9344615   PMID:9349239   PMID:9360944   PMID:9548733   PMID:9737711   PMID:10419448   PMID:10504457   PMID:10859319   PMID:10986281  
PMID:11220743   PMID:11247893   PMID:11320086   PMID:11323016   PMID:11326276   PMID:11375993   PMID:11701474   PMID:11718469   PMID:11729324   PMID:11801551   PMID:11825873   PMID:11841844  
PMID:11925859   PMID:11927011   PMID:11979071   PMID:11983918   PMID:12005165   PMID:12034345   PMID:12034400   PMID:12112311   PMID:12117418   PMID:12464266   PMID:12477932   PMID:12579270  
PMID:12684625   PMID:12759241   PMID:12759346   PMID:12808021   PMID:12958188   PMID:12963695   PMID:14516315   PMID:14744783   PMID:15040016   PMID:15102692   PMID:15149334   PMID:15239678  
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PMID:17728005   PMID:18006768   PMID:18023162   PMID:18036564   PMID:18179407   PMID:18202161   PMID:18214300   PMID:18308831   PMID:18329694   PMID:18340552   PMID:18364512   PMID:18385523  
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PMID:18653469   PMID:18674869   PMID:18695873   PMID:18713744   PMID:18715618   PMID:18721140   PMID:18768525   PMID:18798254   PMID:18805052   PMID:18823373   PMID:18931651   PMID:18955490  
PMID:18958543   PMID:18974372   PMID:19000448   PMID:19016757   PMID:19020757   PMID:19022775   PMID:19094228   PMID:19121849   PMID:19132754   PMID:19173304   PMID:19181662   PMID:19221016  
PMID:19231585   PMID:19266094   PMID:19303106   PMID:19317620   PMID:19329997   PMID:19360357   PMID:19420105   PMID:19421758   PMID:19435861   PMID:19465902   PMID:19505922   PMID:19586554  
PMID:19608871   PMID:19634113   PMID:19643940   PMID:19654318   PMID:19676133   PMID:19679556   PMID:19682489   PMID:19690403   PMID:19690958   PMID:19701966   PMID:19724852   PMID:19728912  
PMID:19730683   PMID:19785773   PMID:19787626   PMID:19789190   PMID:19834535   PMID:19929564   PMID:20007614   PMID:20040080   PMID:20096949   PMID:20113256   PMID:20132413   PMID:20139113  
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PMID:31299414   PMID:31299935   PMID:31342296   PMID:31350432   PMID:31366549   PMID:31576476   PMID:31644669   PMID:31771979   PMID:31827648   PMID:31882462   PMID:32014910   PMID:32101136  
PMID:32373960   PMID:32377701   PMID:32663776   PMID:32892475   PMID:32961536   PMID:33005257   PMID:33139675   PMID:33237244   PMID:33536476   PMID:33581214   PMID:33655961   PMID:33713636  
PMID:33736747   PMID:33809984   PMID:33961781   PMID:33974241   PMID:34117704   PMID:34225019   PMID:34588190   PMID:34588192   PMID:34769248   PMID:34857952   PMID:34973082   PMID:35045102  
PMID:35152729   PMID:35200585   PMID:35288736   PMID:35303536   PMID:35327637   PMID:35343563   PMID:35496040   PMID:35612832   PMID:35717157   PMID:35729470   PMID:35834547   PMID:35852664  
PMID:35904018   PMID:36066668   PMID:36094664   PMID:36150916   PMID:36275703   PMID:36288882   PMID:36361378   PMID:36508772   PMID:36585199   PMID:36645203   PMID:37181812   PMID:37527206  
PMID:37814323   PMID:37902872   PMID:38073039   PMID:38485250   PMID:38522506   PMID:38914992   PMID:38925847  


Genomics

Comparative Map Data
MMP7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811102,520,508 - 102,530,747 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11102,520,508 - 102,530,750 (-)EnsemblGRCh38hg38GRCh38
GRCh3711102,391,239 - 102,401,478 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611101,896,449 - 101,906,688 (-)NCBINCBI36Build 36hg18NCBI36
Build 3411101,896,448 - 101,906,688NCBI
Celera1199,552,782 - 99,563,021 (-)NCBICelera
Cytogenetic Map11q22.2NCBI
HuRef1198,318,241 - 98,328,480 (-)NCBIHuRef
CHM1_111102,274,287 - 102,284,528 (-)NCBICHM1_1
T2T-CHM13v2.011102,522,678 - 102,532,920 (-)NCBIT2T-CHM13v2.0
Mmp7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3997,692,095 - 7,699,587 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl97,692,091 - 7,699,587 (+)EnsemblGRCm39 Ensembl
GRCm3897,692,090 - 7,699,585 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl97,692,090 - 7,699,585 (+)EnsemblGRCm38mm10GRCm38
MGSCv3797,692,111 - 7,699,416 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3697,692,097 - 7,699,255 (+)NCBIMGSCv36mm8
Celera95,082,790 - 5,090,191 (+)NCBICelera
Cytogenetic Map9A1NCBI
cM Map92.46NCBI
Mmp7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8813,133,043 - 13,140,761 (+)NCBIGRCr8
mRatBN7.284,848,186 - 4,855,908 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl84,848,186 - 4,855,902 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx88,808,955 - 8,816,704 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.087,106,740 - 7,114,491 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.085,107,859 - 5,115,573 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.085,893,253 - 5,900,965 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl85,893,249 - 5,901,049 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.085,895,393 - 5,903,105 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.484,526,018 - 4,533,730 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.184,526,033 - 4,533,729 (+)NCBI
Celera86,407,543 - 6,415,255 (+)NCBICelera
Cytogenetic Map8q11NCBI
Mmp7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554125,778,502 - 5,792,445 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554125,780,772 - 5,792,485 (-)NCBIChiLan1.0ChiLan1.0
MMP7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29103,319,695 - 103,329,920 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111104,408,059 - 104,418,283 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01197,467,037 - 97,477,305 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111100,960,107 - 100,970,355 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11100,960,032 - 100,971,099 (-)Ensemblpanpan1.1panPan2
MMP7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1529,187,902 - 29,196,157 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl529,187,851 - 29,196,153 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha529,135,576 - 29,143,842 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0529,239,121 - 29,247,375 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl529,238,932 - 29,247,371 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1529,273,927 - 29,282,176 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0529,153,310 - 29,161,571 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0529,328,802 - 29,337,062 (+)NCBIUU_Cfam_GSD_1.0
Mmp7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494786,138,756 - 86,148,072 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365515,388,459 - 5,395,071 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365515,388,456 - 5,395,071 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MMP7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl933,214,594 - 33,225,080 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1933,214,590 - 33,225,080 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2937,133,037 - 37,143,432 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MMP7
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1193,889,189 - 93,901,077 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl193,889,198 - 93,899,587 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604331,959,442 - 31,969,839 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mmp7
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624878345,038 - 361,652 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624878345,038 - 364,986 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MMP7
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q14.1-22.3(chr11:78232836-106779420)x1 copy number loss See cases [RCV000052710] Chr11:78232836..106779420 [GRCh38]
Chr11:77943882..106650146 [GRCh37]
Chr11:77621530..106155356 [NCBI36]
Chr11:11q14.1-22.3		 pathogenic
GRCh38/hg38 11q14.1-22.2(chr11:85242847-102920097)x1 copy number loss See cases [RCV000052711] Chr11:85242847..102920097 [GRCh38]
Chr11:84953891..102738968 [GRCh37]
Chr11:84631539..102296037 [NCBI36]
Chr11:11q14.1-22.2		 pathogenic
GRCh38/hg38 11q22.1-25(chr11:100348599-135040246)x3 copy number gain See cases [RCV000053638] Chr11:100348599..135040246 [GRCh38]
Chr11:100219331..134910140 [GRCh37]
Chr11:99724541..134415350 [NCBI36]
Chr11:11q22.1-25		 pathogenic
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3		 pathogenic
GRCh38/hg38 11q22.1-22.3(chr11:98357901-106059146)x1 copy number loss See cases [RCV000136574] Chr11:98357901..106059146 [GRCh38]
Chr11:98228629..105929873 [GRCh37]
Chr11:97733839..105435083 [NCBI36]
Chr11:11q22.1-22.3		 pathogenic
GRCh38/hg38 11q22.1-22.3(chr11:101452984-104044105)x3 copy number gain See cases [RCV000136846] Chr11:101452984..104044105 [GRCh38]
Chr11:101323715..103914833 [GRCh37]
Chr11:100828925..103420043 [NCBI36]
Chr11:11q22.1-22.3		 pathogenic
GRCh38/hg38 11q14.3-22.3(chr11:91086659-109595582)x1 copy number loss See cases [RCV000138038] Chr11:91086659..109595582 [GRCh38]
Chr11:90819827..109466308 [GRCh37]
Chr11:90459475..108971518 [NCBI36]
Chr11:11q14.3-22.3		 pathogenic
GRCh37/hg19 11p13-q25(chr11:32799481-134938470)x3 copy number gain MISSED ABORTION [RCV002282973] Chr11:32799481..134938470 [GRCh37]
Chr11:11p13-q25		 pathogenic
GRCh37/hg19 11q22.2(chr11:102323664-102401448)x3 copy number gain See cases [RCV000446744] Chr11:102323664..102401448 [GRCh37]
Chr11:11q22.2		 uncertain significance
GRCh37/hg19 11q22.2(chr11:102376793-102430735)x1 copy number loss See cases [RCV000448042] Chr11:102376793..102430735 [GRCh37]
Chr11:11q22.2		 likely benign
GRCh37/hg19 11q14.2-22.3(chr11:88152458-109414650)x1 copy number loss See cases [RCV000510457] Chr11:88152458..109414650 [GRCh37]
Chr11:11q14.2-22.3		 pathogenic
GRCh37/hg19 11q22.1-22.3(chr11:98515900-104970876)x1 copy number loss See cases [RCV000511844] Chr11:98515900..104970876 [GRCh37]
Chr11:11q22.1-22.3		 likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q13.4-23.3(chr11:71588805-116680918)x3 copy number gain not provided [RCV000683374] Chr11:71588805..116680918 [GRCh37]
Chr11:11q13.4-23.3		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25		 pathogenic
GRCh37/hg19 11q14.1-23.2(chr11:80053454-113316236)x1 copy number loss not provided [RCV000737595] Chr11:80053454..113316236 [GRCh37]
Chr11:11q14.1-23.2		 pathogenic
NM_002423.5(MMP7):c.722C>T (p.Pro241Leu) single nucleotide variant not provided [RCV000947379] Chr11:102523293 [GRCh38]
Chr11:102394024 [GRCh37]
Chr11:11q22.2		 benign
NM_002423.5(MMP7):c.151A>C (p.Asn51His) single nucleotide variant not provided [RCV000887754] Chr11:102527941 [GRCh38]
Chr11:102398672 [GRCh37]
Chr11:11q22.2		 benign
NM_002423.5(MMP7):c.285C>T (p.Tyr95=) single nucleotide variant not provided [RCV000899698] Chr11:102527807 [GRCh38]
Chr11:102398538 [GRCh37]
Chr11:11q22.2		 benign
NM_002423.5(MMP7):c.231C>T (p.Arg77=) single nucleotide variant not provided [RCV000956995] Chr11:102527861 [GRCh38]
Chr11:102398592 [GRCh37]
Chr11:11q22.2		 benign
NM_002423.5(MMP7):c.339C>T (p.Ile113=) single nucleotide variant not provided [RCV000934285] Chr11:102527669 [GRCh38]
Chr11:102398400 [GRCh37]
Chr11:11q22.2		 benign
GRCh37/hg19 11q22.1-22.3(chr11:99059204-103281943)x3 copy number gain not provided [RCV002472738] Chr11:99059204..103281943 [GRCh37]
Chr11:11q22.1-22.3		 uncertain significance
NC_000011.9:g.(?_94153285)_(111965700_?)del deletion Ataxia-telangiectasia syndrome [RCV001389105] Chr11:94153285..111965700 [GRCh37]
Chr11:11q21-23.1		 pathogenic
GRCh37/hg19 11q22.2(chr11:102376794-102439233)x1 copy number loss not provided [RCV001834211] Chr11:102376794..102439233 [GRCh37]
Chr11:11q22.2		 uncertain significance
GRCh37/hg19 11q22.2(chr11:102308740-102676879) copy number gain not specified [RCV002052953] Chr11:102308740..102676879 [GRCh37]
Chr11:11q22.2		 uncertain significance
GRCh37/hg19 11q14.1-23.3(chr11:85422071-118022671)x1 copy number loss not provided [RCV001832892] Chr11:85422071..118022671 [GRCh37]
Chr11:11q14.1-23.3		 uncertain significance
NC_000011.9:g.(?_101323686)_(103349981_?)del deletion Jeune thoracic dystrophy [RCV001942288]|not provided [RCV001942287] Chr11:101323686..103349981 [GRCh37]
Chr11:11q22.1-22.3		 pathogenic|no classifications from unflagged records
NC_000011.9:g.(?_101374735)_(103349981_?)dup duplication not provided [RCV003122918] Chr11:101374735..103349981 [GRCh37]
Chr11:11q22.1-22.3		 uncertain significance
GRCh37/hg19 11q22.1-22.3(chr11:101371503-109306519)x1 copy number loss not provided [RCV002472494] Chr11:101371503..109306519 [GRCh37]
Chr11:11q22.1-22.3		 pathogenic
GRCh37/hg19 11q22.1-22.3(chr11:98770072-104602846)x1 copy number loss not provided [RCV002472602] Chr11:98770072..104602846 [GRCh37]
Chr11:11q22.1-22.3		 likely pathogenic
GRCh37/hg19 11q14.1-22.3(chr11:81478509-104667040)x1 copy number loss not provided [RCV002475722] Chr11:81478509..104667040 [GRCh37]
Chr11:11q14.1-22.3		 pathogenic
NM_002423.5(MMP7):c.71C>T (p.Ala24Val) single nucleotide variant not specified [RCV004119466] Chr11:102530630 [GRCh38]
Chr11:102401361 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.92A>G (p.Gln31Arg) single nucleotide variant not specified [RCV004214786] Chr11:102530609 [GRCh38]
Chr11:102401340 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.20G>A (p.Cys7Tyr) single nucleotide variant not specified [RCV004178807] Chr11:102530681 [GRCh38]
Chr11:102401412 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.730T>G (p.Phe244Val) single nucleotide variant not specified [RCV004237011] Chr11:102523285 [GRCh38]
Chr11:102394016 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.40G>A (p.Gly14Ser) single nucleotide variant not specified [RCV004137166] Chr11:102530661 [GRCh38]
Chr11:102401392 [GRCh37]
Chr11:11q22.2		 likely benign
NM_002423.5(MMP7):c.136G>A (p.Asp46Asn) single nucleotide variant not specified [RCV004264809] Chr11:102527956 [GRCh38]
Chr11:102398687 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.455C>A (p.Ala152Asp) single nucleotide variant not specified [RCV004358726] Chr11:102527553 [GRCh38]
Chr11:102398284 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.536C>T (p.Ala179Val) single nucleotide variant not specified [RCV004358359] Chr11:102525013 [GRCh38]
Chr11:102395744 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.356A>G (p.Asp119Gly) single nucleotide variant not specified [RCV004354886] Chr11:102527652 [GRCh38]
Chr11:102398383 [GRCh37]
Chr11:11q22.2		 uncertain significance
GRCh37/hg19 11q21-22.3(chr11:97147292-102979905)x3 copy number gain not provided [RCV003484850] Chr11:97147292..102979905 [GRCh37]
Chr11:11q21-22.3		 uncertain significance
Single allele duplication not provided [RCV003448710] Chr11:102134973..134945611 [GRCh37]
Chr11:11q22.2-25		 pathogenic
NM_002423.5(MMP7):c.470G>A (p.Gly157Asp) single nucleotide variant not specified [RCV004460185] Chr11:102527538 [GRCh38]
Chr11:102398269 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.382T>G (p.Leu128Val) single nucleotide variant not specified [RCV004460060] Chr11:102527626 [GRCh38]
Chr11:102398357 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.403A>T (p.Met135Leu) single nucleotide variant not specified [RCV004460086] Chr11:102527605 [GRCh38]
Chr11:102398336 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.56C>T (p.Pro19Leu) single nucleotide variant not specified [RCV004460267] Chr11:102530645 [GRCh38]
Chr11:102401376 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.589C>T (p.Arg197Cys) single nucleotide variant not specified [RCV004643154] Chr11:102524960 [GRCh38]
Chr11:102395691 [GRCh37]
Chr11:11q22.2		 uncertain significance
NM_002423.5(MMP7):c.557T>C (p.Leu186Pro) single nucleotide variant not specified [RCV004643155] Chr11:102524992 [GRCh38]
Chr11:102395723 [GRCh37]
Chr11:11q22.2		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:336
Count of miRNA genes:279
Interacting mature miRNAs:286
Transcripts:ENST00000260227, ENST00000531200, ENST00000533366
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407103799GWAS752775_Hobsolete_prostate specific antigen measurement QTL GWAS752775 (human)3e-25obsolete_prostate specific antigen measurement11102525876102525877Human
407044646GWAS693622_Hmatrilysin measurement QTL GWAS693622 (human)5e-37matrilysin measurement11102525516102525517Human
407256019GWAS904995_Hmatrilysin measurement QTL GWAS904995 (human)4e-31matrilysin measurement11102520936102520937Human
407044651GWAS693627_Hmatrilysin measurement QTL GWAS693627 (human)4e-18matrilysin measurement11102528865102528866Human
407062361GWAS711337_Hmatrix metalloproteinase 7 measurement QTL GWAS711337 (human)6e-28matrix metalloproteinase 7 measurement11102527703102527704Human
406899195GWAS548171_Hmatrix metalloproteinase 7 measurement QTL GWAS548171 (human)0.000007matrix metalloproteinase 7 measurement11102526274102526275Human
1559115SCL20_HSerum cholesterol level QTL 20 (human)3.220.001213Lipid levelLDL cholesterol11100442501126442501Human
406972460GWAS621436_Hobsolete_prostate specific antigen measurement QTL GWAS621436 (human)8e-12obsolete_prostate specific antigen measurement11102525876102525877Human
407213546GWAS862522_Hprostate carcinoma QTL GWAS862522 (human)1e-08prostate carcinoma11102525876102525877Human

Markers in Region
RH46951  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3711102,391,367 - 102,391,491UniSTSGRCh37
Build 3611101,896,577 - 101,896,701RGDNCBI36
Celera1199,552,910 - 99,553,034RGD
Cytogenetic Map11q21-q22UniSTS
HuRef1198,318,369 - 98,318,493UniSTS
GeneMap99-GB4 RH Map11348.76UniSTS
SGC35374  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map11q21-q22UniSTS
GeneMap99-GB4 RH Map11348.76UniSTS
Whitehead-RH Map11464.6UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1070 1829 2149 1648 3091 1409 2090 4 596 1388 441 2032 5436 4908 22 2020 1 822 1568 1382 168 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_002423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AH006461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI675414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK222980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001830 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY795972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003635 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP332706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB109660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ399600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GN341824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X07819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Z11887 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000260227   ⟹   ENSP00000260227
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11102,520,508 - 102,530,747 (-)Ensembl
Ensembl Acc Id: ENST00000531200
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11102,526,986 - 102,530,747 (-)Ensembl
Ensembl Acc Id: ENST00000533366
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl11102,524,276 - 102,530,750 (-)Ensembl
RefSeq Acc Id: NM_002423   ⟹   NP_002414
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811102,520,508 - 102,530,747 (-)NCBI
GRCh3711102,391,239 - 102,401,478 (-)ENTREZGENE
Build 3611101,896,449 - 101,906,688 (-)NCBI Archive
HuRef1198,318,241 - 98,328,480 (-)ENTREZGENE
CHM1_111102,274,287 - 102,284,534 (-)NCBI
T2T-CHM13v2.011102,522,678 - 102,532,920 (-)NCBI
Sequence:
RefSeq Acc Id: NP_002414   ⟸   NM_002423
- Peptide Label: preproprotein
- UniProtKB: Q9BTK9 (UniProtKB/Swiss-Prot),   P09237 (UniProtKB/Swiss-Prot),   Q53GF1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000260227   ⟸   ENST00000260227
Protein Domains
Peptidase M10 metallopeptidase   Peptidase metallopeptidase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P09237-F1-model_v2 AlphaFold P09237 1-267 view protein structure

Promoters
RGD ID:6789111
Promoter ID:HG_KWN:14039
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:NM_002423,   UC009YXD.1
Position:
Human AssemblyChrPosition (strand)Source
Build 3611101,906,296 - 101,906,796 (-)MPROMDB
RGD ID:7221915
Promoter ID:EPDNEW_H16703
Type:initiation region
Name:MMP7_1
Description:matrix metallopeptidase 7
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh3811102,530,747 - 102,530,807EPDNEW
RGD ID:6849906
Promoter ID:EP48001
Type:single initiation site
Name:HS_MMP7
Description:Matrix metalloproteinase 7 (matrilysin, uterine).
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Tissues & Cell Lines:glandular epithelium
Experiment Methods:Sequencing of a full-length cDNA; Primer extension
Position:No map positions available.

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:7174 AgrOrtholog
COSMIC MMP7 COSMIC
Ensembl Genes ENSG00000137673 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000260227 ENTREZGENE
  ENST00000260227.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000137673 GTEx
HGNC ID HGNC:7174 ENTREZGENE
Human Proteome Map MMP7 Human Proteome Map
InterPro M10A_MMP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10_metallopeptidase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pept_M10A_Zn_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidoglycan-bd-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:4316 UniProtKB/Swiss-Prot
NCBI Gene 4316 ENTREZGENE
OMIM 178990 OMIM
PANTHER MATRILYSIN UniProtKB/TrEMBL
  MATRIX METALLOPROTEINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10201:SF143 UniProtKB/Swiss-Prot
Pfam Peptidase_M10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PG_binding_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30887 PharmGKB
PRINTS MATRIXIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE CYSTEINE_SWITCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PGBD-like UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A5GZ72_HUMAN UniProtKB/TrEMBL
  MMP7_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q53GF1 ENTREZGENE, UniProtKB/TrEMBL
  Q9BTK9 ENTREZGENE
UniProt Secondary Q9BTK9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-03-03 MMP7  matrix metallopeptidase 7  MMP7  matrix metallopeptidase 7 (matrilysin, uterine)  Symbol and/or name change 5135510 APPROVED