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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736005
Species: Homo sapiens
RGD Object: Gene
Symbol: MMP7
Name: matrix metallopeptidase 7
Acc ID: CHEBI:6541
Term: losartan
Definition: A biphenylyltetrazole where a 1,1'-biphenyl group is attached at the 5-position and has an additional trisubstituted imidazol-1-ylmethyl group at the 4'-position
Chemical ID: MESH:D019808
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
MMP7multiple interactionsEXP 6480464CTDICG 001 promotes the reaction [Losartan inhibits the reaction [AGT protein results in increased expression of MMP7 protein]]; Losartan inhibits the reaction [AGT protein results in increased expression of MMP7 protein]; Losartan promotes the reaction [ICG 001 inhibits the reaction [AGT protein results in increased expression of MMP7 protein]]PMID:28578904
MMP7multiple interactionsISOMmp7 (Mus musculus)6480464CTDLosartan inhibits the reaction [AGT protein results in increased expression of MMP7 protein]PMID:28578904
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