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Gene: SOD3 (superoxide dismutase 3) Homo sapiens
Symbol: SOD3
Name: superoxide dismutase 3
Description: Predicted to have copper ion binding activity and superoxide dismutase activity. Predicted to be involved in removal of superoxide radicals. Localizes to the collagen-containing extracellular matrix. Implicated in several diseases, including coronary artery disease (multiple); diabetes mellitus (multiple); diabetic retinopathy; lung disease (multiple); and polyneuropathy. Biomarker of intermediate coronary syndrome and myocardial infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EC-SOD; extracellular superoxide dismutase; extracellular superoxide dismutase [Cu-Zn]; MGC20077; superoxide dismutase 3, extracellular; testicular tissue protein Li 175
Mus musculus (house mouse) : Sod3 (superoxide dismutase 3, extracellular)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sod3 (superoxide dismutase 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sod3 (superoxide dismutase 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SOD3 (superoxide dismutase 3)
Canis lupus familiaris (dog) : SOD3 (superoxide dismutase 3)
Sus scrofa (pig) : SOD3 (superoxide dismutase 3)
Chlorocebus sabaeus (green monkey) : SOD3 (superoxide dismutase 3)
Heterocephalus glaber (naked mole-rat) : Sod3 (superoxide dismutase 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl424,789,912 - 24,800,842 (+)Ensembl
GRCh38424,795,478 - 24,800,845 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37424,797,085 - 24,802,467 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36424,406,183 - 24,411,565 (+)NCBINCBI36hg18NCBI36
Build 34424,472,323 - 24,478,733NCBI
Celera425,246,551 - 25,251,936 (+)NCBI
Cytogenetic Map4p15.2NCBI
HuRef424,139,594 - 24,144,972 (+)NCBIHuRef
CHM1_1424,796,442 - 24,801,824 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SOD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736515
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.