CRP (C-reactive protein) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: CRP (C-reactive protein) Homo sapiens
Analyze
Symbol: CRP
Name: C-reactive protein
RGD ID: 736633
HGNC Page HGNC:2367
Description: Enables several functions, including complement component C1q complex binding activity; low-density lipoprotein particle binding activity; and low-density lipoprotein particle receptor binding activity. Involved in several processes, including negative regulation of macrophage derived foam cell differentiation; positive regulation of superoxide anion generation; and regulation of gene expression. Acts upstream of or within vasoconstriction. Located in extracellular space. Implicated in several diseases, including Kawasaki disease; autoimmune disease (multiple); macular degeneration (multiple); middle cerebral artery infarction; and nephritis (multiple). Biomarker of several diseases, including auditory system disease (multiple); autoimmune disease (multiple); cardiovascular system disease (multiple); eye disease (multiple); and lung disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C-reactive protein, pentraxin-related; c-reactive protein, petaxin related; MGC149895; MGC88244; pentraxin 1; PTX1
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: CRPP1  
Allele / Splice: See ClinVar data
Candidate Gene For: GLUCO117_H GLUCO120_H GLUCO149_H GLUCO177_H GLUCO223_H
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene has been reviewed for its involvement in coronavirus biology, and is involved in cytokine storm inflammatory response.
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381159,712,289 - 159,714,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1159,712,289 - 159,714,589 (-)EnsemblGRCh38hg38GRCh38
GRCh371159,682,079 - 159,684,379 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,948,703 - 157,951,003 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,495,152 - 156,497,452NCBI
Celera1132,750,525 - 132,752,817 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,038,539 - 131,040,831 (-)NCBIHuRef
CHM1_11161,076,594 - 161,078,894 (-)NCBICHM1_1
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (IEP)
Acute Coronary Syndrome  (EXP,IDA,IEP)
acute kidney failure  (IDA,ISO)
acute stress disorder  (IEP)
Acute Uveitis  (IEP,ISO)
aggressive periodontitis  (IEP)
Albuminuria  (IEP)
alcoholic liver cirrhosis  (IEP)
Alzheimer's disease  (ISO)
ankylosing spondylitis  (IEP)
antiphospholipid syndrome  (IDA)
anxiety disorder  (EXP,IEP)
Arsenic Poisoning  (EXP)
arthritis  (IAGP)
aspergillosis  (IEP)
asthma  (IEP)
atherosclerosis  (EXP,IEP)
atrial fibrillation  (IEP)
autoimmune interstitial lung, joint, and kidney disease  (IAGP)
Bacteremia  (IEP)
bacterial infectious disease  (IEP)
bacterial meningitis  (IEP)
Behcet's disease  (IEP)
Brain Hypoxia-Ischemia  (IDA)
Brain Injuries  (IEP)
breast cancer  (IEP)
breast carcinoma  (IEP)
bronchiolitis  (IEP)
Burns  (ISO)
Cardiac Arrhythmias  (IEP)
cardiovascular system disease  (EXP,IEP,TAS)
cerebrovascular disease  (EXP)
Chemical and Drug Induced Liver Injury  (EXP)
Chronic Hepatitis C  (IDA)
chronic obstructive pulmonary disease  (EXP,IEP)
colon cancer  (ISO)
congestive heart failure  (EXP)
Contrast-Induced Nephropathy  (IDA)
coronary artery disease  (EXP,IEP)
COVID-19  (EXP,IEP)
Crohn's disease  (EXP,IEP)
depressive disorder  (IEP)
Diabetic Foot  (IEP)
Diabetic Nephropathies  (IDA,IEP)
diabetic retinopathy  (EXP,IEP)
disease by infectious agent  (EXP)
disease of metabolism  (EXP)
Drug Hypersensitivity Syndrome  (EXP)
end stage renal disease  (EXP,IEP)
Experimental Arthritis  (EXP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (ISO)
Fever of Unknown Origin  (IEP)
gastrointestinal stromal tumor  (IAGP)
heart disease  (EXP,IDA)
hepatocellular carcinoma  (EXP)
human immunodeficiency virus infectious disease  (IDA)
Human Influenza  (IEP)
hypertension  (EXP,IDA,IEP,ISO)
hypertensive retinopathy  (IEP)
Hypertriglyceridemia  (EXP)
Hypoxia  (IEP)
Inflammation  (EXP,IAGP,ISO)
inflammatory bowel disease  (IDA)
intermediate coronary syndrome  (IEP)
interstitial cystitis  (IEP)
interstitial nephritis  (EXP,IMP,ISO)
Intestinal Reperfusion Injury  (ISO)
iron deficiency anemia  (ISO)
juvenile rheumatoid arthritis  (IEP)
Kawasaki disease  (IAGP)
kidney failure  (IEP)
Kuhnt-Junius degeneration  (IAGP,IEP)
Left Ventricular Hypertrophy  (IEP)
leishmaniasis  (EXP)
liver cirrhosis  (IEP)
low tension glaucoma  (IEP)
Lung Neoplasms  (EXP)
lupus nephritis  (IAGP,IDA)
Lymphatic Metastasis  (IAGP)
lymphopenia  (IAGP)
macular degeneration  (IDA,IEP)
malaria  (EXP)
mastoiditis  (IEP)
meningitis  (EXP)
metabolic dysfunction and alcohol associated liver disease  (ISO)
Metabolic Syndrome  (EXP,IMP)
mevalonic aciduria  (IEP)
middle cerebral artery infarction  (IDA)
mouth disease  (ISO)
Mycoplasma pneumoniae pneumonia  (IEP)
myocardial infarction  (IEP,ISO)
Myocardial Ischemia  (EXP,ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (EXP)
Neonatal Sepsis  (ISO)
non-arteritic anterior ischemic optic neuropathy  (IEP)
obesity  (EXP,IEP,ISO)
obstructive sleep apnea  (IDA)
opiate dependence  (IEP)
otitis externa  (IEP)
otitis media  (IEP)
overactive bladder syndrome  (IEP)
parathyroid carcinoma  (IAGP)
Parkinson's disease  (IEP)
Pasteurellaceae Infections  (EXP)
pelvic inflammatory disease  (IEP)
periodontitis  (EXP)
pharyngoconjunctival fever  (IEP)
Pneumococcal Pneumonia  (IEP)
pneumonia  (IEP)
polymyalgia rheumatica  (IEP)
Polypoidal Choroidal Vasculopathy  (IEP)
Postoperative Atrial Fibrillation  (IEP)
Pseudomonas Infections  (IDA,ISO)
psoriasis  (EXP,IEP)
pulmonary hypertension  (IEP)
pulmonary sarcoidosis  (IEP)
pulmonary tuberculosis  (IEP)
pyelonephritis  (ISO)
renal cell carcinoma  (IEP)
Renal Colic  (IDA)
renal fibrosis  (IMP,ISO)
renal hypertension  (ISO)
retinal vein occlusion  (IEP)
rheumatoid arthritis  (EXP,IEP,ISO)
secondary hyperparathyroidism  (EXP)
Sepsis  (IEP,ISO)
Serositis  (IAGP)
Sjogren's syndrome  (IEP)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stevens-Johnson syndrome  (EXP)
systemic lupus erythematosus  (EXP,IDA)
temporal arteritis  (IEP)
thrombosis  (EXP)
Tubulointerstitial Nephritis and Uveitis  (IEP)
type 1 diabetes mellitus  (EXP,IEP)
type 2 diabetes mellitus  (IEP)
urticaria  (IEP)
uveal melanoma  (IEP)
vestibular neuronitis  (IEP)
visceral leishmaniasis  (EXP)
withdrawal disorder  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoic acid  (EXP)
(R)-lipoic acid  (ISO)
(R,R,R)-alpha-tocopherol  (EXP)
1,1-dichloroethene  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (EXP)
2-trans,6-trans,10-trans-geranylgeranyl diphosphate  (EXP)
3',5'-cyclic AMP  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (EXP,ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (EXP)
7,12-dimethyltetraphene  (ISO)
abacavir  (EXP)
acalabrutinib  (EXP)
acetamide  (ISO)
acetic acid  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
alclofenac  (EXP)
aluminium atom  (EXP)
aluminium(0)  (EXP)
amiodarone  (EXP)
amlodipine  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
apigenin  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (ISO)
atorvastatin calcium  (EXP,ISO)
benidipine  (ISO)
benzbromarone  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzylpenicillin  (ISO)
bezafibrate  (EXP)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bivalirudin  (EXP)
boron atom  (ISO)
Botulinum toxin type A  (ISO)
Bromperidol  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (EXP)
calcitriol  (EXP)
candesartan  (EXP)
carbon monoxide  (EXP)
carbon nanotube  (ISO)
carnosine  (ISO)
carrageenan  (ISO)
carvedilol  (EXP,ISO)
celecoxib  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibric acid  (ISO)
clozapine  (EXP)
cobalt dichloride  (ISO)
cocaine  (EXP)
colesevelam hydrochloride  (EXP)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP,ISO)
curcumin  (ISO)
cyanocob(III)alamin  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
cyproterone acetate  (EXP)
D-penicillamine  (EXP)
daidzein  (EXP)
delta-tocotrienol  (EXP)
deoxynivalenol  (ISO)
desferrioxamine B  (ISO)
desogestrel  (EXP)
dexamethasone  (ISO)
Diallyl sulfide  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diclofenac  (EXP,ISO)
dienogest  (EXP)
diethyl phthalate  (ISO)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
disodium selenite  (EXP,ISO)
doxazosin  (EXP)
elemental boron  (ISO)
endosulfan  (ISO)
epoxiconazole  (ISO)
eptifibatide  (EXP)
erythromycin A  (ISO)
ethanol  (EXP,ISO)
ezetimibe  (EXP)
fenofibrate  (EXP)
flucloxacillin  (EXP)
flunitrazepam  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fosfomycin  (EXP)
fructose  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gamma-tocopherol  (EXP)
genistein  (EXP,ISO)
gentamycin  (EXP,ISO)
geraniol  (ISO)
gestodene  (EXP)
ginsenoside Re  (ISO)
gossypin  (ISO)
heparin  (EXP)
indinavir  (EXP)
indometacin  (ISO)
iron(2+) sulfate (anhydrous)  (EXP)
iron(III) citrate  (EXP)
isoprenaline  (ISO)
ivermectin  (EXP)
kaempferol  (EXP)
L-arginine  (ISO)
L-ascorbic acid  (EXP)
lead diacetate  (ISO)
lead(0)  (EXP)
levonorgestrel  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
losartan  (ISO)
lovastatin  (ISO)
lupeol  (ISO)
medroxyprogesterone acetate  (EXP)
Mesaconitine  (ISO)
metformin  (EXP,ISO)
methotrexate  (ISO)
mevalonic acid  (EXP)
milrinone  (EXP)
mono(2-ethyl-5-hydroxyhexyl) phthalate  (EXP)
mono(2-ethyl-5-oxohexyl) phthalate  (EXP)
monobenzyl phthalate  (EXP)
Monobutylphthalate  (EXP)
morphine  (EXP)
myricitrin  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
neoechinulin A  (ISO)
nickel atom  (EXP)
nickel dichloride  (EXP)
nicotinic acid  (EXP,ISO)
nitrofen  (ISO)
nitrogen dioxide  (EXP)
nomegestrol  (EXP)
nomegestrol acetate  (EXP)
Nonidet P-40  (EXP)
norgestimate  (EXP)
O-methyleugenol  (EXP)
obeticholic acid  (EXP)
oleic acid  (EXP)
olmesartan  (EXP)
Olmesartan medoxomil  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
pamidronate  (EXP)
paracetamol  (EXP,ISO)
Pentoxifylline  (EXP)
perfluorobutanesulfonic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenethyl caffeate  (ISO)
phenobarbital  (EXP)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidylcholine  (EXP)
pioglitazone  (EXP,ISO)
pirinixic acid  (ISO)
pravastatin  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propiconazole  (ISO)
pterostilbene  (EXP)
quercetin  (EXP,ISO)
resveratrol  (EXP,ISO)
riboflavin  (EXP)
rifampicin  (EXP)
rifamycin SV  (EXP)
rivastigmine  (ISO)
rosmarinic acid  (ISO)
rosuvastatin calcium  (EXP)
rotenone  (ISO)
salvianolic acid B  (EXP,ISO)
SB 203580  (EXP)
simvastatin  (EXP)
sodium arsenite  (EXP,ISO)
sodium nitrite  (ISO)
sterigmatocystin  (ISO)
streptozocin  (ISO)
superoxide  (ISO)
telmisartan  (EXP)
testosterone  (EXP)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thioacetamide  (ISO)
tibolone  (EXP)
titanium dioxide  (ISO)
TMC-120A  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
Triptolide  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (EXP)
vitamin E  (EXP,ISO)
withaferin A  (ISO)
wortmannin  (EXP)
zaragozic acid A  (ISO)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP)
zinc(0)  (EXP,ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Postoperative atrial fibrillation is not correlated to C-reactive protein. Ahlsson AJ, etal., Ann Thorac Surg. 2007 Apr;83(4):1332-7.
2. Hospitalised patients with Influenza A (H1N1) in the Royal Hospital, Oman: Experience of a tertiary care hospital, July-December 2009. Al-Lawati J, etal., Sultan Qaboos Univ Med J. 2010 Dec;10(3):326-34. Epub 2010 Nov 14.
3. Plasma oxidative and inflammatory markers in patients with idiopathic Parkinson's disease. Andican G, etal., Acta Neurol Belg. 2012 Feb 9.
4. The value of C-reactive protein determination in patients with renal colic to decide urgent urinary diversion. Angulo JC, etal., Urology. 2010 Aug;76(2):301-6. Epub 2010 Mar 5.
5. The effectiveness of Echinacea extract or composite glucosamine, chondroitin and methyl sulfonyl methane supplements on acute and chronic rheumatoid arthritis rat model. Arafa NM, etal., Toxicol Ind Health. 2011 Dec 15.
6. Atheroma plaque, metabolic syndrome and inflammation in patients with psoriasis. Arias-Santiago S, etal., Eur J Dermatol. 2012 Apr 16.
7. C-reactive protein (CRP): An important diagnostic and prognostic tool in nursing-home-associated pneumonia. Arinzon Z, etal., Arch Gerontol Geriatr. 2011 Mar 23.
8. Long-term outcome of tumor necrosis factor alpha antagonist's treatment in pediatric Crohn's disease. Assa A, etal., J Crohns Colitis. 2012 Apr 4.
9. Association between C-reactive protein and generalized anxiety disorder in stable coronary heart disease patients. Bankier B, etal., Eur Heart J. 2008 Sep;29(18):2212-7. doi: 10.1093/eurheartj/ehn326. Epub 2008 Jul 4.
10. The effects of melatonin on burn-induced inflammatory responses and coagulation disorders in rats. Bekyarova G, etal., Methods Find Exp Clin Pharmacol. 2010 Jun;32(5):299-303.
11. Promotion of beta-amyloid production by C-reactive protein and its implications in the early pathogenesis of Alzheimer's disease. Bi BT, etal., Neurochem Int. 2012 Feb;60(3):257-66. Epub 2011 Dec 19.
12. Platelet count, mean platelet volume and smoking status in stable chronic obstructive pulmonary disease. Biljak VR, etal., Platelets. 2011 Apr 20.
13. Relationship between inflammatory markers, oxidant-antioxidant status and intima-media thickness in prepubertal children with juvenile idiopathic arthritis. Breda L, etal., Clin Res Cardiol. 2012 Aug 11.
14. Effects of topical indomethacin, bromfenac and nepafenac on lipopolysaccharide-induced ocular inflammation. Bucolo C, etal., J Pharm Pharmacol. 2014 Jul;66(7):954-60. doi: 10.1111/jphp.12224. Epub 2014 Feb 12.
15. Synergistic effects of aminoglycosides and fosfomycin on Pseudomonas aeruginosa in vitro and biofilm infections in a rat model. Cai Y, etal., J Antimicrob Chemother. 2009 Sep;64(3):563-6. Epub 2009 Jun 26.
16. Accuracy of white blood cell count, C-reactive protein, interleukin-6 and tumor necrosis factor alpha for diagnosing late neonatal sepsis. Caldas JP, etal., J Pediatr (Rio J). 2008 Nov-Dec;84(6):536-42. doi: doi:10.2223/JPED.1838.
17. Lack of effect of a single injection of human C-reactive protein on murine lupus or nephrotoxic nephritis. Carlucci F, etal., Arthritis Rheum. 2010 Jan;62(1):245-9.
18. Early proinflammatory cytokines and C-reactive protein trends as predictors of outcome in invasive Aspergillosis. Chai L, etal., J Infect Dis. 2010 Nov 1;202(9):1454-62. doi: 10.1086/656527.
19. Significant elevation of plasma pentraxin 3 in patients with pelvic inflammatory disease. Chang CC, etal., Clin Chem Lab Med. 2011 Oct;49(10):1655-60. doi: 10.1515/CCLM.2011.650. Epub 2011 Jun 17.
20. Augmented nitric oxide generation in neutrophils: oxidative and pro-inflammatory implications in hypertension. Chatterjee M, etal., Free Radic Res. 2009 Dec;43(12):1195-204.
21. [Promoting effect of granulocyto-colony stimulating factor on neovascularization in rats with myocardial infarction]. Chen T, etal., Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2010 Oct;24(10):1239-43.
22. Molecular and clinical characteristics of adenoviral infections in Taiwanese children in 2004-2005. Cheng CC, etal., Eur J Pediatr. 2008 Jun;167(6):633-40. Epub 2007 Sep 18.
23. Inflammatory gene polymorphisms and susceptibility to kawasaki disease and its arterial sequelae. Cheung YF, etal., Pediatrics. 2008 Sep;122(3):e608-14. doi: 10.1542/peds.2008-0646. Epub 2008 Aug 18.
24. Mastoiditis diagnosed by clinical symptoms and imaging studies in children: disease spectrum and evolving diagnostic challenges. Chien JH, etal., J Microbiol Immunol Infect. 2012 Oct;45(5):377-81. doi: 10.1016/j.jmii.2011.12.008. Epub 2012 May 9.
25. Malignant otitis externa: an Australian case series. Chin R, etal., Surgeon. 2012 Oct;10(5):273-7. doi: 10.1016/j.surge.2011.09.004. Epub 2011 Oct 26.
26. C-reactive protein elevation in patients with atrial arrhythmias: inflammatory mechanisms and persistence of atrial fibrillation. Chung MK, etal., Circulation. 2001 Dec 11;104(24):2886-91.
27. Elevation of serum c-reactive protein in patients with OAB and IC/BPS implies chronic inflammation in the urinary bladder. Chung SD, etal., Neurourol Urodyn. 2011 Mar;30(3):417-20. doi: 10.1002/nau.20938. Epub 2011 Jan 31.
28. The association of low-grade systemic inflammation with hypertensive retinopathy. Coban E, etal., Clin Exp Hypertens. 2010;32(8):528-31. doi: 10.3109/10641963.2010.496519.
29. Inflammation reduces HDL protection against primary cardiac risk. Corsetti JP, etal., Eur J Clin Invest. 2010 Jun;40(6):483-9. doi: 10.1111/j.1365-2362.2010.02287.x. Epub 2010 Apr 14.
30. Role of thrombocytosis in diagnosis of giant cell arteritis and differentiation of arteritic from non-arteritic anterior ischemic optic neuropathy. Costello F, etal., Eur J Ophthalmol. 2004 May-Jun;14(3):245-57.
31. Complement activation in patients with COVID-19: A novel therapeutic target. Cugno M, etal., J Allergy Clin Immunol. 2020 May 14. pii: S0091-6749(20)30650-3. doi: 10.1016/j.jaci.2020.05.006.
32. [Assess the impact of concentrations of inflammatory markers IL-6, CRP in the presence of albuminuria in patients with type 2 diabetes]. Czyzewska J, etal., Pol Merkur Lekarski. 2012 Feb;32(188):98-102.
33. C-reactive protein and atrial fibrillation in idiopathic dilated cardiomyopathy. Dai S, etal., Clin Cardiol. 2009 Sep;32(9):E45-50. doi: 10.1002/clc.20430.
34. Selection of Symptomatic Patients With Crohn's Disease for Abdominopelvic Computed Tomography: Role of Serum C-Reactive Protein. Desmond AN, etal., Can Assoc Radiol J. 2012 Mar 14.
35. Retinal vein occlusion: C-reactive protein and arterial hypertension. Dodson PM and Shine B, Acta Ophthalmol (Copenh). 1984 Feb;62(1):123-30.
36. Iron deficiency and renal development in the newborn rat. Drake KA, etal., Pediatr Res. 2009 Dec;66(6):619-24.
37. Cytokine activation during attacks of the hyperimmunoglobulinemia D and periodic fever syndrome. Drenth JP, etal., Blood. 1995 Jun 15;85(12):3586-93.
38. Decreased autoantibody levels and enhanced survival of (NZB x NZW) F1 mice treated with C-reactive protein. Du Clos TW, etal., Clin Immunol Immunopathol. 1994 Jan;70(1):22-7.
39. Risk factors for recurrence of diabetic foot ulcers: prospective follow-up analysis of a Eurodiale subgroup. Dubsky M, etal., Int Wound J. 2012 Jun 19. doi: 10.1111/j.1742-481X.2012.01022.x.
40. Periodontitis in humans and non-human primates: oral-systemic linkage inducing acute phase proteins. Ebersole JL, etal., Ann Periodontol. 2002 Dec;7(1):102-11.
41. Correlation of oxidative stress and inflammatory markers with the severity of sickle cell nephropathy. Emokpae MA, etal., Ann Afr Med. 2010 Jul-Sep;9(3):141-6.
42. Risk factors for contrast induced nephropathy: A study among Italian patients. Evola S, etal., Indian Heart J. 2012 Sep-Oct;64(5):484-91. doi: 10.1016/j.ihj.2012.07.007. Epub 2012 Jul 27.
43. Role of quercetin and arginine in ameliorating nano zinc oxide-induced nephrotoxicity in rats. Faddah LM, etal., BMC Complement Altern Med. 2012 May 2;12:60.
44. Complement factor H Y402H and C-reactive protein polymorphism and photodynamic therapy response in age-related macular degeneration. Feng X, etal., Ophthalmology. 2009 Oct;116(10):1908-12.e1. doi: 10.1016/j.ophtha.2009.03.011. Epub 2009 Aug 18.
45. Autoantibodies against C-reactive protein: clinical associations in systemic lupus erythematosus and primary antiphospholipid syndrome. Figueredo MA, etal., J Rheumatol. 2006 Oct;33(10):1980-6.
46. C-reactive protein is released in the coronary circulation and causes endothelial dysfunction in patients with acute coronary syndromes. Forte L, etal., Int J Cardiol. 2011 Oct 6;152(1):7-12. doi: 10.1016/j.ijcard.2011.05.062. Epub 2011 Jul 26.
47. Effect of antibacterial cathelicidin peptide CAP18/LL-37 on sepsis in neonatal rats. Fukumoto K, etal., Pediatr Surg Int. 2005 Jan;21(1):20-4. doi: 10.1007/s00383-004-1256-x.
48. Diagnostic utility of clinical laboratory data determinations for patients with the severe COVID-19. Gao Y, etal., J Med Virol. 2020 Jul;92(7):791-796. doi: 10.1002/jmv.25770. Epub 2020 Apr 10.
49. Serum markers of inflammation and oxidative stress in chronic opium (Taryak) smokers. Ghazavi A, etal., Immunol Lett. 2013 Jun;153(1-2):22-6. doi: 10.1016/j.imlet.2013.07.001. Epub 2013 Jul 12.
50. Effect of a high-fat diet on the hepatic expression of nuclear receptors and their target genes: relevance to drug disposition. Ghoneim RH, etal., Br J Nutr. 2015 Feb 14;113(3):507-16. doi: 10.1017/S0007114514003717. Epub 2015 Jan 23.
51. Human C-reactive protein increases cerebral infarct size after middle cerebral artery occlusion in adult rats. Gill R, etal., J Cereb Blood Flow Metab. 2004 Nov;24(11):1214-8.
52. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
53. C-reactive protein levels do not correlate with retinal artery occlusion but with atherosclerosis. Goldenberg-Cohen N, etal., Eye (Lond). 2009 Apr;23(4):785-90. doi: 10.1038/eye.2008.159. Epub 2008 Jun 6.
54. Adeno-associated virus-mediated human C-reactive protein gene delivery causes endothelial dysfunction and hypertension in rats. Guan H, etal., Clin Chem. 2009 Feb;55(2):274-84. doi: 10.1373/clinchem.2008.115857. Epub 2008 Dec 4.
55. Docosahexaenoic acid, but not eicosapentaenoic acid, reduces the early inflammatory response following compression spinal cord injury in the rat. Hall JC, etal., J Neurochem. 2012 Jun;121(5):738-50. doi: 10.1111/j.1471-4159.2012.07726.x. Epub 2012 Apr 12.
56. Inhibition of classical complement activation attenuates liver ischaemia and reperfusion injury in a rat model. Heijnen BH, etal., Clin Exp Immunol. 2006 Jan;143(1):15-23.
57. Blood plasma inflammation markers during epileptogenesis in post-status epilepticus rat model for temporal lobe epilepsy. Holtman L, etal., Epilepsia. 2013 Apr;54(4):589-95. doi: 10.1111/epi.12112. Epub 2013 Feb 8.
58. Using IL-2R/lymphocytes for predicting the clinical progression of patients with COVID-19. Hou H, etal., Clin Exp Immunol. 2020 Jul;201(1):76-84. doi: 10.1111/cei.13450. Epub 2020 May 15.
59. Systemic inflammation and innate immune response in patients with previous anterior uveitis. Huhtinen M, etal., Br J Ophthalmol. 2002 Apr;86(4):412-7.
60. C-reactive protein and uric Acid levels in patients with psoriasis. Isha, etal., Indian J Clin Biochem. 2011 Jul;26(3):309-11. doi: 10.1007/s12291-011-0132-4. Epub 2011 May 4.
61. [The relationship between inflammatory mediators and pulmonary hypertension in patients with chronic obstructive pulmonary disease]. Jiang YW, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2011 Dec;34(12):904-8.
62. Association of serum glycated albumin, C-reactive protein and ICAM-1 levels with diffuse coronary artery disease in patients with type 2 diabetes mellitus. Jin C, etal., Clin Chim Acta. 2009 Oct;408(1-2):45-9. Epub 2009 Jul 15.
63. Association between SLE nephritis and polymorphic variants of the CRP and FcgammaRIIIa genes. Jonsen A, etal., Rheumatology (Oxford). 2007 Sep;46(9):1417-21. Epub 2007 Jun 27.
64. Acute phase inflammatory markers in patients with non-steroidal anti-inflammatory drugs (NSAIDs)-induced acute urticaria/angioedema and after aspirin challenge. Kasperska-Zajac A, etal., J Eur Acad Dermatol Venereol. 2012 Feb 21. doi: 10.1111/j.1468-3083.2012.04486.x.
65. Elevated C-reactive protein levels in patients with polypoidal choroidal vasculopathy and patients with neovascular age-related macular degeneration. Kikuchi M, etal., Ophthalmology. 2007 Sep;114(9):1722-7. Epub 2007 Apr 2.
66. Human C-reactive protein enhances vulnerability of immature rats to hypoxic-ischemic brain damage: a preliminary study. Kinugasa-Taniguchi Y, etal., Reprod Sci. 2010 May;17(5):419-25. doi: 10.1177/1933719110361379. Epub 2010 Mar 10.
67. Value of serum C-reactive protein concentrations in febrile children without apparent focus. Kohli V, etal., Ann Trop Paediatr. 1993;13(4):373-8.
68. Long-term prognostic value of baseline C-reactive protein in predicting recurrence of atrial fibrillation after electrical cardioversion. Korantzopoulos P, etal., Pacing Clin Electrophysiol. 2008 Oct;31(10):1272-6. doi: 10.1111/j.1540-8159.2008.01177.x.
69. Lipid peroxidation and erythrocyte antioxidant enzymes in patients with Behcet's disease. Kose K, etal., Tohoku J Exp Med. 2002 May;197(1):9-16.
70. Value of procalcitonin, C-reactive protein, and neopterin in exacerbations of chronic obstructive pulmonary disease. Lacoma A, etal., Int J Chron Obstruct Pulmon Dis. 2011;6:157-69. Epub 2011 Feb 28.
71. Acute-phase proteins and serum immunoglobulins in ankylosing spondylitis. Laurent MR and Panayi GS, Ann Rheum Dis. 1983 Oct;42(5):524-8.
72. Microalbuminuria in non-diabetic stemi: An independent predictor for acute kidney injury. Lazzeri C, etal., Scand Cardiovasc J. 2012 Jul 10.
73. Pre-ART Levels of Inflammation and Coagulation Markers Are Strong Predictors of Death in a South African Cohort with Advanced HIV Disease. Ledwaba L, etal., PLoS One. 2012;7(3):e24243. Epub 2012 Mar 20.
74. Severity of obstructive sleep apnea syndrome and high-sensitivity C-reactive protein reduced after relocation pharyngoplasty. Lee LA, etal., Otolaryngol Head Neck Surg. 2011 Apr;144(4):632-8. Epub 2011 Feb 10.
75. Analysis of systemic endothelin-1, matrix metalloproteinase-9, macrophage chemoattractant protein-1, and high-sensitivity C-reactive protein in normal-tension glaucoma. Lee NY, etal., Curr Eye Res. 2012 Dec;37(12):1121-6. doi: 10.3109/02713683.2012.725798. Epub 2012 Sep 11.
76. C-reactive protein levels in normal tension glaucoma. Leibovitch I, etal., J Glaucoma. 2005 Oct;14(5):384-6.
77. Cardiovascular disease potentially contributes to the progression and poor prognosis of COVID-19. Li M, etal., Nutr Metab Cardiovasc Dis. 2020 Jun 25;30(7):1061-1067. doi: 10.1016/j.numecd.2020.04.013. Epub 2020 Apr 18.
78. Clinical and pathological investigation of severe COVID-19 patients. Li S, etal., JCI Insight. 2020 May 19. pii: 138070. doi: 10.1172/jci.insight.138070.
79. C-reactive protein promotes acute renal inflammation and fibrosis in unilateral ureteral obstructive nephropathy in mice. Li ZI, etal., Lab Invest. 2011 Jun;91(6):837-51. Epub 2011 Mar 7.
80. Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein. Liu SL, etal., J Biomed Sci. 2011 Aug 1;18:52. doi: 10.1186/1423-0127-18-52.
81. Cardiovascular disease in U.S. patients with metabolic syndrome, diabetes, and elevated C-reactive protein. Malik S, etal., Diabetes Care. 2005 Mar;28(3):690-3.
82. Serum C-reactive protein in polymyalgia rheumatica. A prospective serial study. Mallya RK, etal., Arthritis Rheum. 1985 Apr;28(4):383-7.
83. Iron-binding proteins and C-reactive protein in Nipple Aspirate Fluids: role of Iron-driven inflammation in breast cancer microenvironment? Mannello F, etal., Am J Transl Res. 2010 Oct 30;3(1):100-13.
84. Lipoprotein (a) and acute-phase response in patients with vestibular neuronitis. Milionis HJ, etal., Eur J Clin Invest. 2003 Dec;33(12):1045-50.
85. C-Reactive protein levels but not CRP dynamics predict mortality in patients with pneumococcal pneumonia. Mooiweer E, etal., J Infect. 2011 Apr;62(4):314-6. Epub 2011 Jan 31.
86. High-sensitivity C-reactive protein levels predict survival and are related to haemodynamics in alcoholic cirrhosis. Mortensen C, etal., Eur J Gastroenterol Hepatol. 2012 Mar 20.
87. Cardiorenal syndrome in hypertensive rats: microalbuminuria, inflammation and ventricular hypertrophy. Moubarak M, etal., Physiol Res. 2012 Mar 6;61(1):13-24. Epub 2011 Dec 20.
88. Diagnostic markers of serious bacterial infections in febrile infants younger than 90 days old. Nosrati A, etal., Pediatr Int. 2014 Feb;56(1):47-52. doi: 10.1111/ped.12191.
89. Is inflammation a new risk factor of depression in haemodialysis patients? Nowak L, etal., Int Urol Nephrol. 2012 Sep 13.
90. Antioxidant potential, paraoxonase 1, ceruloplasmin activity and C-reactive protein concentration in diabetic retinopathy. Nowak M, etal., Clin Exp Med. 2010 Sep;10(3):185-92. doi: 10.1007/s10238-009-0084-7. Epub 2009 Dec 11.
91. Serum amyloid A and C-reactive protein levels may predict microalbuminuria and macroalbuminuria in newly diagnosed type 1 diabetic patients. Overgaard AJ, etal., J Diabetes Complications. 2012 Aug 10.
92. C-reactive protein and natural IgM antibodies are activators of complement in a rat model of intestinal ischemia and reperfusion. Padilla ND, etal., Surgery. 2007 Nov;142(5):722-33.
93. Chronic infections & coronary artery disease with special reference to Chalmydia pneumoniae. Padmavati S, etal., Indian J Med Res. 2012 Feb;135(2):228-32.
94. Incidence and predisposing factors for severe disease in previously healthy term infants experiencing their first episode of bronchiolitis. Papoff P, etal., Acta Paediatr. 2011 Feb 1. doi: 10.1111/j.1651-2227.2011.02181.x.
95. Long-term dietary antioxidant cocktail supplementation effectively reduces renal inflammation in diabetic mice. Park NY, etal., Br J Nutr. 2011 Nov;106(10):1514-21. Epub 2011 Jun 3.
96. C-reactive protein levels are elevated in asthma and asthma-like conditions. Pellizzaro AM and Heuertz RM, Clin Lab Sci. 2010 Fall;23(4):223-7.
97. C-reactive protein for rapid monitoring of infections of the central nervous system. Peltola HO Lancet. 1982 May 1;1(8279):980-2.
98. Systemic exposure to Pseudomonal bacteria: a potential link between type 1 diabetes and chronic inflammation. Peraneva L, etal., Acta Diabetol. 2012 Aug 5.
99. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
100. Effects of human C-reactive protein on pathogenesis of features of the metabolic syndrome. Pravenec M, etal., Hypertension. 2011 Apr;57(4):731-7. Epub 2011 Feb 28.
101. Serum procalcitonin in pulmonary tuberculosis. Rasmussen TA, etal., Int J Tuberc Lung Dis. 2011 Feb;15(2):251-6, i.
102. Incremental prognostic value of serum levels of troponin T and C-reactive protein on admission in patients with unstable angina pectoris. Rebuzzi AG, etal., Am J Cardiol. 1998 Sep 15;82(6):715-9.
103. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
104. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
105. Experimental alveolitis in rats: microbiological, acute phase response and histometric characterization of delayed alveolar healing. Rodrigues MT, etal., J Appl Oral Sci. 2011 May-Jun;19(3):260-8.
106. Reversal of ongoing proteinuria in autoimmune mice by treatment with C-reactive protein. Rodriguez W, etal., Arthritis Rheum. 2005 Feb;52(2):642-50.
107. Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China. Ruan Q, etal., Intensive Care Med. 2020 May;46(5):846-848. doi: 10.1007/s00134-020-05991-x. Epub 2020 Mar 3.
108. Chemopreventive efficacy of green tea drinking against 1,2-dimethyl hydrazine-induced rat colon carcinogenesis. Sadik NA Cell Biochem Funct. 2012 Sep 24. doi: 10.1002/cbf.2873.
109. Pretherapeutic laboratory findings, extent of metastasis and choice of treatment as prognostic markers in ocular melanoma- a single centre experience. Schicher N, etal., J Eur Acad Dermatol Venereol. 2013 Mar;27(3):e394-9. doi: 10.1111/jdv.12006. Epub 2012 Oct 12.
110. C-reactive protein and CFH, ARMS2/HTRA1 gene variants are independently associated with risk of macular degeneration. Seddon JM, etal., Ophthalmology. 2010 Aug;117(8):1560-6. doi: 10.1016/j.ophtha.2009.11.020. Epub 2010 Mar 26.
111. Role of gender in the associations of microalbuminuria with inflammatory markers in hypertensive subjects: a cross-sectional study. Shantha GP, etal., Kidney Blood Press Res. 2009;32(6):434-9. Epub 2009 Dec 17.
112. C reactive protein (CRP) as a predictor for true bacteremia in children. Shaoul R, etal., Med Sci Monit. 2008 May;14(5):CR255-261.
113. Progressive Increase of Inflammatory Biomarkers in Chronic Kidney Disease and End-Stage Renal Disease. Sharain K, etal., Clin Appl Thromb Hemost. 2012 Aug 3.
114. Up-regulation of PPARgamma, heat shock protein-27 and -72 by naringin attenuates insulin resistance, beta-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. Sharma AK, etal., Br J Nutr. 2011 Dec;106(11):1713-23. Epub 2011 Jun 21.
115. High-sensitivity C-reactive protein: an independent risk factor for left ventricular hypertrophy in patients with lupus nephritis. Shi B, etal., J Biomed Biotechnol. 2010;2010:373426. Epub 2010 Nov 7.
116. Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus. Sjowall C, etal., Arthritis Res Ther. 2004;6(2):R87-94. Epub 2003 Dec 5.
117. High prevalence of autoantibodies to C-reactive protein in patients with chronic hepatitis C infection: association with liver fibrosis and portal inflammation. Sjowall C, etal., Hum Immunol. 2012 Apr;73(4):382-8. Epub 2012 Feb 1.
118. Association of posttraumatic stress disorder with low-grade elevation of C-reactive protein: evidence from the general population. Spitzer C, etal., J Psychiatr Res. 2010 Jan;44(1):15-21. doi: 10.1016/j.jpsychires.2009.06.002. Epub 2009 Jul 22.
119. Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients. Steffens S, etal., BMC Cancer. 2012 Sep 8;12(1):399.
120. Elevated C-reactive protein levels may be a predictor of persistent unfavourable symptoms in patients with mild traumatic brain injury: a preliminary study. Su SH, etal., Brain Behav Immun. 2014 May;38:111-7. doi: 10.1016/j.bbi.2014.01.009. Epub 2014 Jan 21.
121. The effects of C-reactive protein, interleukin-6, and tumor necrosis factor-alpha in rat allograft adventitial inflammation and allograft arteriosclerosis. Sun H, etal., Transplant Proc. 2009 Nov;41(9):3909-12.
122. C-reactive protein predicts response to infliximab in patients with chronic sarcoidosis. Sweiss NJ, etal., Sarcoidosis Vasc Diffuse Lung Dis. 2010 Jul;27(1):49-56.
123. Association between baseline levels of C-reactive protein (CRP) and a dinucleotide repeat polymorphism in the intron of the CRP gene. Szalai AJ, etal., Genes Immun. 2002 Feb;3(1):14-9.
124. Modified C-reactive protein might be a target autoantigen of TINU syndrome. Tan Y, etal., Clin J Am Soc Nephrol. 2011 Jan;6(1):93-100. Epub 2010 Sep 2.
125. Autoantibodies against monomeric C-reactive protein in sera from patients with lupus nephritis are associated with disease activity and renal tubulointerstitial lesions. Tan Y, etal., Hum Immunol. 2008 Dec;69(12):840-4. Epub 2008 Oct 11.
126. A model of experimental acute hematogenous pyelonephritis in the rat. Tancheva S, etal., Folia Med (Plovdiv). 2011 Apr-Jun;53(2):63-8.
127. Ampicillin/sulbactam for children hospitalized with community-acquired pneumonia. Tapisiz A, etal., J Infect Chemother. 2011 Jan 22.
128. Use of C-reactive protein in differentiation between acute bacterial and viral otitis media. Tejani NR, etal., Pediatrics. 1995 May;95(5):664-9.
129. Evaluation of the potential for lymph node metastasis using CRP 1846C>T genetic polymorphism in invasive breast cancer. Terata K, etal., Tumour Biol. 2014 Jun;35(6):5931-5. doi: 10.1007/s13277-014-1786-3. Epub 2014 Mar 16.
130. The levels of soluble CD40 ligand and C-reactive protein in normal weight, overweight and obese people. Unek IT, etal., Clin Med Res. 2010 Jul;8(2):89-95.
131. Biomarkers of cardiovascular disease as risk factors for age-related macular degeneration. Vine AK, etal., Ophthalmology. 2005 Dec;112(12):2076-80. Epub 2005 Oct 12.
132. Clinical features and treatment of COVID-19 patients in northeast Chongqing. Wan S, etal., J Med Virol. 2020 Jul;92(7):797-806. doi: 10.1002/jmv.25783. Epub 2020 Apr 1.
133. Reduced serum levels of autoantibodies against monomeric C-reactive protein (CRP) in patients with acute coronary syndrome. Wettero J, etal., Clin Chim Acta. 2009 Feb;400(1-2):128-31. Epub 2008 Oct 17.
134. The time-averaged inflammatory disease activity estimates the progression of erosions in MRI of the sacroiliac joints in ankylosing spondylitis. Wick MC, etal., Clin Rheumatol. 2012 Mar 16.
135. Antiretroviral treatment-associated tuberculosis in a prospective cohort of HIV-infected patients starting ART. Worodria W, etal., Clin Dev Immunol. 2011;2011:758350. Epub 2010 Dec 8.
136. [Preliminary investigation of the changes and mechanism of Leptin after myocardial ischemia/reperfusion injury]. Xue H, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2010 Nov;22(11):680-3.
137. Clinical characteristics and outcomes of patients with severe covid-19 with diabetes. Yan Y, etal., BMJ Open Diabetes Res Care. 2020 Apr;8(1). pii: 8/1/e001343. doi: 10.1136/bmjdrc-2020-001343.
138. [Effect of electroacupuncture intervention on blood-lipid, high-sensitivity C-reactive protein and adiponectin levels in hyperlipidemia rats]. Yan ZK, etal., Zhen Ci Yan Jiu. 2013 Oct;38(5):365-8, 385.
139. Leptin, triglycerides, and interleukin 6 are independently associated with C-reactive protein in Japanese type 2 diabetic patients. Yanagawa T, etal., Diabetes Res Clin Pract. 2007 Jan;75(1):2-6. Epub 2006 Jun 9.
140. Factors Associated with Hypoxemia in Children Infected with Pandemic H1N1 2009 Influenza Virus. Yeom JS, etal., Pediatr Int. 2010 Dec 30. doi: 10.1111/j.1442-200X.2010.03319.x.
141. Proteomic analysis of aortic smooth muscle cell secretions reveals an association of myosin heavy chain 11 with abdominal aortic aneurysm. Yokoyama U, etal., Am J Physiol Heart Circ Physiol. 2018 Jul 13. doi: 10.1152/ajpheart.00329.2018.
142. Raised C-reactive protein response in rheumatoid arthritis patients with secondary Sjogren's syndrome. Youinou P, etal., Rheumatol Int. 1990;10(1):39-41.
143. The correlation between viral clearance and biochemical outcomes of 94 COVID-19 infected discharged patients. Yuan J, etal., Inflamm Res. 2020 Jun;69(6):599-606. doi: 10.1007/s00011-020-01342-0. Epub 2020 Mar 29.
144. [Assessment of changes in levels of interleukin 6 and C reactive protein in patients with breast tumors]. Zakrzewska I, etal., Pol Merkur Lekarski. 2003 Aug;15(86):115-7.
145. Viral and host factors related to the clinical outcome of COVID-19. Zhang X, etal., Nature. 2020 May 20. pii: 10.1038/s41586-020-2355-0. doi: 10.1038/s41586-020-2355-0.
146. The clinical characteristics and outcomes of patients with diabetes and secondary hyperglycaemia with coronavirus disease 2019: A single-centre, retrospective, observational study in Wuhan. Zhang Y, etal., Diabetes Obes Metab. 2020 May 14. doi: 10.1111/dom.14086.
147. [Value of fluorescence quantitative PCR assay of bronchoalveolar lavage fluid samples in the diagnosis of Mycoplasma pneumoniae pneumonia in children.] Zhong LL, etal., Zhongguo Dang Dai Er Ke Za Zhi. 2011 Mar;13(3):191-194.
Additional References at PubMed
PMID:265538   PMID:403526   PMID:762075   PMID:1477104   PMID:1989977   PMID:2477447   PMID:2477488   PMID:2997165   PMID:3759147   PMID:3840479   PMID:6427230   PMID:6685157  
PMID:6693419   PMID:6857266   PMID:7881902   PMID:8144569   PMID:8482924   PMID:8599761   PMID:8613143   PMID:10368284   PMID:10408362   PMID:10490997   PMID:10675363   PMID:11027634  
PMID:11801683   PMID:11947917   PMID:11964845   PMID:11991668   PMID:12033985   PMID:12037301   PMID:12055255   PMID:12102655   PMID:12104096   PMID:12151853   PMID:12186793   PMID:12198121  
PMID:12213988   PMID:12218140   PMID:12234944   PMID:12244213   PMID:12351483   PMID:12390313   PMID:12393563   PMID:12426217   PMID:12426218   PMID:12460042   PMID:12471137   PMID:12477932  
PMID:12529491   PMID:12552583   PMID:12563060   PMID:12594844   PMID:12616974   PMID:12618085   PMID:12637157   PMID:12654086   PMID:12663465   PMID:12701054   PMID:12716818   PMID:12783932  
PMID:12819031   PMID:12821545   PMID:12835213   PMID:12835218   PMID:12842840   PMID:12850811   PMID:12869354   PMID:12892901   PMID:12934049   PMID:12975260   PMID:14500938   PMID:14506615  
PMID:14508181   PMID:14592848   PMID:14634117   PMID:14718574   PMID:14744975   PMID:14967730   PMID:14967837   PMID:14983228   PMID:15044210   PMID:15047644   PMID:15078802   PMID:15136507  
PMID:15271790   PMID:15277326   PMID:15286457   PMID:15304023   PMID:15306744   PMID:15308783   PMID:15337754   PMID:15358216   PMID:15380464   PMID:15448085   PMID:15456743   PMID:15469865  
PMID:15472120   PMID:15489334   PMID:15517131   PMID:15565375   PMID:15579759   PMID:15585208   PMID:15585211   PMID:15585215   PMID:15585218   PMID:15591095   PMID:15653107   PMID:15692104  
PMID:15746456   PMID:15766555   PMID:15772777   PMID:15777561   PMID:15778807   PMID:15795363   PMID:15797975   PMID:15798948   PMID:15798966   PMID:15808312   PMID:15853546   PMID:15859024  
PMID:15860734   PMID:15866055   PMID:15867284   PMID:15878871   PMID:15887860   PMID:15894122   PMID:15894827   PMID:15897982   PMID:15919817   PMID:15920036   PMID:15920065   PMID:15920074  
PMID:15950309   PMID:15955385   PMID:15955391   PMID:15993896   PMID:15996056   PMID:15997206   PMID:16005364   PMID:16005367   PMID:16026589   PMID:16051899   PMID:16061741   PMID:16087790  
PMID:16087807   PMID:16109328   PMID:16123325   PMID:16131811   PMID:16148535   PMID:16151032   PMID:16153429   PMID:16170833   PMID:16189249   PMID:16213874   PMID:16221209   PMID:16257408  
PMID:16266402   PMID:16306468   PMID:16344720   PMID:16352308   PMID:16380821   PMID:16405882   PMID:16409458   PMID:16417933   PMID:16500582   PMID:16501036   PMID:16511556   PMID:16534007  
PMID:16549465   PMID:16550411   PMID:16565153   PMID:16580524   PMID:16582918   PMID:16603696   PMID:16618976   PMID:16642000   PMID:16643876   PMID:16681424   PMID:16682383   PMID:16685271  
PMID:16698114   PMID:16710414   PMID:16719793   PMID:16723442   PMID:16731635   PMID:16733231   PMID:16751408   PMID:16765355   PMID:16778366   PMID:16803998   PMID:16809555   PMID:16809564  
PMID:16832147   PMID:16832152   PMID:16840032   PMID:16847147   PMID:16854501   PMID:16858645   PMID:16864904   PMID:16879213   PMID:16881737   PMID:16908949   PMID:16916777   PMID:16963054  
PMID:16984505   PMID:17003778   PMID:17011566   PMID:17044845   PMID:17044846   PMID:17079491   PMID:17082472   PMID:17101857   PMID:17110595   PMID:17113035   PMID:17113059   PMID:17114654  
PMID:17126343   PMID:17138933   PMID:17141244   PMID:17143564   PMID:17148079   PMID:17149558   PMID:17157301   PMID:17164456   PMID:17185152   PMID:17202380   PMID:17211240   PMID:17219082  
PMID:17220790   PMID:17234298   PMID:17244159   PMID:17261875   PMID:17264952   PMID:17279354   PMID:17289011   PMID:17292342   PMID:17293598   PMID:17325687   PMID:17327459   PMID:17335789  
PMID:17335903   PMID:17339482   PMID:17343862   PMID:17347578   PMID:17350021   PMID:17351284   PMID:17355554   PMID:17355643   PMID:17369452   PMID:17372148   PMID:17380191   PMID:17382928  
PMID:17383146   PMID:17395501   PMID:17399790   PMID:17400881   PMID:17433639   PMID:17449131   PMID:17449922   PMID:17452737   PMID:17456635   PMID:17459567   PMID:17460724   PMID:17477779  
PMID:17477815   PMID:17498578   PMID:17499233   PMID:17511977   PMID:17513778   PMID:17519779   PMID:17530289   PMID:17531242   PMID:17561469   PMID:17573060   PMID:17575367   PMID:17581635  
PMID:17584642   PMID:17588586   PMID:17597836   PMID:17598370   PMID:17600233   PMID:17613401   PMID:17615382   PMID:17623721   PMID:17623828   PMID:17635239   PMID:17641153   PMID:17650829  
PMID:17652082   PMID:17652155   PMID:17653654   PMID:17673235   PMID:17676666   PMID:17693973   PMID:17697822   PMID:17700210   PMID:17702862   PMID:17702963   PMID:17706955   PMID:17714716  
PMID:17714718   PMID:17722225   PMID:17763921   PMID:17765290   PMID:17785206   PMID:17785926   PMID:17806085   PMID:17827818   PMID:17845537   PMID:17851127   PMID:17851695   PMID:17852082  
PMID:17852826   PMID:17873311   PMID:17878721   PMID:17878753   PMID:17880812   PMID:17885262   PMID:17888441   PMID:17891599   PMID:17900590   PMID:17903293   PMID:17909163   PMID:17917609  
PMID:17920229   PMID:17925606   PMID:17934713   PMID:17942113   PMID:17943468   PMID:17952446   PMID:17956875   PMID:17957146   PMID:17981284   PMID:17991470   PMID:18000615   PMID:18005189  
PMID:18023360   PMID:18036188   PMID:18054331   PMID:18055473   PMID:18055714   PMID:18056120   PMID:18060926   PMID:18063701   PMID:18071779   PMID:18075240   PMID:18078625   PMID:18083122  
PMID:18096828   PMID:18165866   PMID:18167554   PMID:18171282   PMID:18172744   PMID:18178503   PMID:18182444   PMID:18200582   PMID:18206145   PMID:18214695   PMID:18216376   PMID:18217154  
PMID:18218989   PMID:18219371   PMID:18219765   PMID:18226363   PMID:18226879   PMID:18235049   PMID:18241613   PMID:18245530   PMID:18250134   PMID:18262272   PMID:18263601   PMID:18266777  
PMID:18279706   PMID:18280482   PMID:18285551   PMID:18285696   PMID:18288276   PMID:18289549   PMID:18296838   PMID:18297417   PMID:18305316   PMID:18312679   PMID:18316365   PMID:18322245  
PMID:18327405   PMID:18328265   PMID:18332893   PMID:18333373   PMID:18344622   PMID:18347271   PMID:18347963   PMID:18356846   PMID:18359028   PMID:18362454   PMID:18365276   PMID:18369665  
PMID:18372435   PMID:18373721   PMID:18378435   PMID:18379563   PMID:18383516   PMID:18385179   PMID:18385676   PMID:18385743   PMID:18385816   PMID:18386294   PMID:18388036   PMID:18388037  
PMID:18389332   PMID:18393253   PMID:18394761   PMID:18401567   PMID:18403728   PMID:18404970   PMID:18412163   PMID:18413218   PMID:18414778   PMID:18415802   PMID:18418236   PMID:18421029  
PMID:18422436   PMID:18425592   PMID:18428198   PMID:18433460   PMID:18436879   PMID:18436884   PMID:18439548   PMID:18439552   PMID:18450770   PMID:18458051   PMID:18464913   PMID:18476570  
PMID:18486609   PMID:18489822   PMID:18491455   PMID:18493116   PMID:18499652   PMID:18500540   PMID:18505467   PMID:18508060   PMID:18513241   PMID:18513823   PMID:18523031   PMID:18541797  
PMID:18551710   PMID:18556380   PMID:18562472   PMID:18566104   PMID:18573122   PMID:18573197   PMID:18573495   PMID:18577830   PMID:18591402   PMID:18605934   PMID:18607165   PMID:18609082  
PMID:18609102   PMID:18616717   PMID:18621860   PMID:18622582   PMID:18624398   PMID:18632424   PMID:18636307   PMID:18650775   PMID:18654020   PMID:18654021   PMID:18667998   PMID:18675273  
PMID:18676680   PMID:18685607   PMID:18688084   PMID:18695743   PMID:18700811   PMID:18702945   PMID:18704199   PMID:18704713   PMID:18708524   PMID:18714381   PMID:18714384   PMID:18753723  
PMID:18753952   PMID:18755462   PMID:18757054   PMID:18759279   PMID:18764931   PMID:18784972   PMID:18785307   PMID:18786923   PMID:18790479   PMID:18791482   PMID:18793001   PMID:18801352  
PMID:18805107   PMID:18805592   PMID:18810599   PMID:18810717   PMID:18818748   PMID:18823889   PMID:18829218   PMID:18835219   PMID:18836266   PMID:18840622   PMID:18841009   PMID:18842294  
PMID:18842390   PMID:18845301   PMID:18853099   PMID:18853133   PMID:18924263   PMID:18937150   PMID:18948966   PMID:18952164   PMID:18953261   PMID:18957790   PMID:18971492   PMID:18974842  
PMID:18983663   PMID:18996288   PMID:18997194   PMID:19004040   PMID:19008293   PMID:19010993   PMID:19011614   PMID:19019335   PMID:19023151   PMID:19025443   PMID:19026696   PMID:19029268  
PMID:19034331   PMID:19040303   PMID:19055599   PMID:19060910   PMID:19067532   PMID:19072030   PMID:19073362   PMID:19074515   PMID:19074985   PMID:19075099   PMID:19076828   PMID:19077177  
PMID:19077918   PMID:19078972   PMID:19081678   PMID:19084272   PMID:19095725   PMID:19096002   PMID:19100387   PMID:19101671   PMID:19111610   PMID:19117239   PMID:19118119   PMID:19122170  
PMID:19125286   PMID:19128923   PMID:19130414   PMID:19136614   PMID:19136826   PMID:19138871   PMID:19139603   PMID:19139754   PMID:19147740   PMID:19155486   PMID:19160050   PMID:19168253  
PMID:19170196   PMID:19170684   PMID:19172699   PMID:19178964   PMID:19179966   PMID:19188531   PMID:19191811   PMID:19193941   PMID:19201044   PMID:19201207   PMID:19202332   PMID:19203753  
PMID:19225207   PMID:19228486   PMID:19238141   PMID:19240794   PMID:19244088   PMID:19248087   PMID:19251259   PMID:19252093   PMID:19255512   PMID:19262552   PMID:19267250   PMID:19267370  
PMID:19268605   PMID:19268941   PMID:19270348   PMID:19272152   PMID:19276622   PMID:19281089   PMID:19282426   PMID:19282606   PMID:19282863   PMID:19297430   PMID:19297456   PMID:19322079  
PMID:19323703   PMID:19328934   PMID:19337791   PMID:19343415   PMID:19351632   PMID:19358836   PMID:19359657   PMID:19360108   PMID:19362308   PMID:19369869   PMID:19375128   PMID:19377212  
PMID:19377253   PMID:19387251   PMID:19390179   PMID:19394732   PMID:19403254   PMID:19410251   PMID:19415164   PMID:19415283   PMID:19423540   PMID:19426506   PMID:19428053   PMID:19433520  
PMID:19436122   PMID:19436291   PMID:19436676   PMID:19436686   PMID:19437230   PMID:19439300   PMID:19439303   PMID:19461040   PMID:19469014   PMID:19473152   PMID:19480860   PMID:19482283  
PMID:19492468   PMID:19494488   PMID:19495883   PMID:19499327   PMID:19501581   PMID:19501644   PMID:19520972   PMID:19521085   PMID:19522741   PMID:19523464   PMID:19525580   PMID:19527514  
PMID:19533498   PMID:19534672   PMID:19538326   PMID:19545442   PMID:19560102   PMID:19565490   PMID:19567438   PMID:19568166   PMID:19571581   PMID:19576194   PMID:19577754   PMID:19578796  
PMID:19584180   PMID:19594772   PMID:19595394   PMID:19602903   PMID:19609738   PMID:19614793   PMID:19617288   PMID:19619902   PMID:19620133   PMID:19624831   PMID:19625176   PMID:19626399  
PMID:19631649   PMID:19642908   PMID:19643839   PMID:19643942   PMID:19644070   PMID:19667982   PMID:19670170   PMID:19680263   PMID:19692168   PMID:19695857   PMID:19706826   PMID:19715516  
PMID:19719987   PMID:19719993   PMID:19728551   PMID:19729797   PMID:19736474   PMID:19736479   PMID:19751919   PMID:19755616   PMID:19760027   PMID:19762396   PMID:19762397   PMID:19766699  
PMID:19783155   PMID:19796676   PMID:19800416   PMID:19801321   PMID:19806245   PMID:19808368   PMID:19816865   PMID:19816870   PMID:19818961   PMID:19821022   PMID:19833744   PMID:19834334  
PMID:19850242   PMID:19850925   PMID:19851048   PMID:19853918   PMID:19855269   PMID:19857655   PMID:19857676   PMID:19864399   PMID:19874580   PMID:19879773   PMID:19900432   PMID:19903811  
PMID:19906786   PMID:19913121   PMID:19914996   PMID:19923014   PMID:19929715   PMID:19931932   PMID:19942863   PMID:19944144   PMID:19946607   PMID:19947988   PMID:19948975   PMID:19954777  
PMID:19956729   PMID:19962488   PMID:19965533   PMID:20004425   PMID:20005739   PMID:20006362   PMID:20017311   PMID:20024640   PMID:20031768   PMID:20034371   PMID:20036017   PMID:20042240  
PMID:20047081   PMID:20056225   PMID:20056955   PMID:20060752   PMID:20068351   PMID:20074254   PMID:20075180   PMID:20075509   PMID:20075574   PMID:20078870   PMID:20078877   PMID:20083961  
PMID:20131075   PMID:20136960   PMID:20138378   PMID:20142117   PMID:20145391   PMID:20145925   PMID:20170291   PMID:20173307   PMID:20179497   PMID:20184510   PMID:20184533   PMID:20184536  
PMID:20186934   PMID:20190687   PMID:20200626   PMID:20200627   PMID:20211068   PMID:20214668   PMID:20215002   PMID:20219150   PMID:20227257   PMID:20227921   PMID:20233980   PMID:20237496  
PMID:20306065   PMID:20333461   PMID:20339115   PMID:20339904   PMID:20346360   PMID:20348053   PMID:20359087   PMID:20371432   PMID:20386340   PMID:20403997   PMID:20406964   PMID:20423474  
PMID:20423919   PMID:20437055   PMID:20438785   PMID:20443669   PMID:20453000   PMID:20453690   PMID:20465852   PMID:20466978   PMID:20485444   PMID:20489166   PMID:20494358   PMID:20494378  
PMID:20502295   PMID:20511616   PMID:20522534   PMID:20531240   PMID:20537668   PMID:20538124   PMID:20538278   PMID:20538960   PMID:20539018   PMID:20546810   PMID:20552244   PMID:20556836  
PMID:20573938   PMID:20581772   PMID:20587599   PMID:20592333   PMID:20596037   PMID:20596713   PMID:20599197   PMID:20605213   PMID:20610232   PMID:20614004   PMID:20618287   PMID:20623261  
PMID:20626020   PMID:20626239   PMID:20626701   PMID:20628086   PMID:20638228   PMID:20640440   PMID:20651278   PMID:20669343   PMID:20670634   PMID:20676960   PMID:20679960   PMID:20680929  
PMID:20683147   PMID:20686879   PMID:20690093   PMID:20691829   PMID:20703235   PMID:20704541   PMID:20706769   PMID:20709501   PMID:20722986   PMID:20727736   PMID:20730440   PMID:20733302  
PMID:20734449   PMID:20797493   PMID:20805569   PMID:20813565   PMID:20819268   PMID:20836727   PMID:20843812   PMID:20846522   PMID:20846939   PMID:20850446   PMID:20852043   PMID:20855282  
PMID:20855565   PMID:20856253   PMID:20874781   PMID:20877716   PMID:20881941   PMID:20883364   PMID:20929576   PMID:20929699   PMID:20930309   PMID:20939118   PMID:20949557   PMID:20952358  
PMID:20967757   PMID:20972697   PMID:20974458   PMID:20978825   PMID:20979755   PMID:21029360   PMID:21029457   PMID:21033124   PMID:21034294   PMID:21037097   PMID:21037509   PMID:21043803  
PMID:21044752   PMID:21044781   PMID:21054666   PMID:21054877   PMID:21059738   PMID:21062467   PMID:21067752   PMID:21071964   PMID:21080913   PMID:21081932   PMID:21089116   PMID:21094359  
PMID:21105323   PMID:21108561   PMID:21135979   PMID:21136015   PMID:21143859   PMID:21143879   PMID:21146168   PMID:21149504   PMID:21161711   PMID:21162890   PMID:21167068   PMID:21172733  
PMID:21173097   PMID:21173540   PMID:21182750   PMID:21190868   PMID:21194909   PMID:21195701   PMID:21196492   PMID:21203342   PMID:21204606   PMID:21215477   PMID:21218608   PMID:21226995  
PMID:21258804   PMID:21270838   PMID:21287288   PMID:21293934   PMID:21294915   PMID:21296145   PMID:21296900   PMID:21300955   PMID:21305296   PMID:21309051   PMID:21309632   PMID:21315565  
PMID:21323571   PMID:21324310   PMID:21325005   PMID:21325757   PMID:21357824   PMID:21360619   PMID:21383176   PMID:21402418   PMID:21404895   PMID:21406102   PMID:21413847   PMID:21414621  
PMID:21415385   PMID:21444086   PMID:21447704   PMID:21455669   PMID:21458205   PMID:21465964   PMID:21476028   PMID:21493089   PMID:21508123   PMID:21516340   PMID:21519150   PMID:21526633  
PMID:21536287   PMID:21546857   PMID:21553357   PMID:21565862   PMID:21570260   PMID:21575917   PMID:21592994   PMID:21602602   PMID:21617097   PMID:21624120   PMID:21625240   PMID:21630214  
PMID:21640994   PMID:21645137   PMID:21647738   PMID:21655904   PMID:21658317   PMID:21679689   PMID:21685272   PMID:21696613   PMID:21697747   PMID:21700090   PMID:21714897   PMID:21716910  
PMID:21719129   PMID:21720757   PMID:21729568   PMID:21729973   PMID:21730823   PMID:21737650   PMID:21740772   PMID:21741099   PMID:21757662   PMID:21773944   PMID:21801245   PMID:21804277  
PMID:21814873   PMID:21816845   PMID:21819975   PMID:21821037   PMID:21831326   PMID:21832113   PMID:21839826   PMID:21843630   PMID:21845926   PMID:21856781   PMID:21859817   PMID:21868617  
PMID:21872279   PMID:21873635   PMID:21883780   PMID:21890096   PMID:21901123   PMID:21915265   PMID:21923250   PMID:21928234   PMID:21930971   PMID:21931794   PMID:21933586   PMID:21934067  
PMID:21937998   PMID:21951717   PMID:21958326   PMID:21970447   PMID:21979047   PMID:21988832   PMID:21993388   PMID:22004660   PMID:22014839   PMID:22018511   PMID:22019947   PMID:22019953  
PMID:22025173   PMID:22025360   PMID:22038335   PMID:22048011   PMID:22055258   PMID:22056216   PMID:22079264   PMID:22082888   PMID:22095223   PMID:22103876   PMID:22104116   PMID:22119118  
PMID:22134501   PMID:22153152   PMID:22158621   PMID:22166506   PMID:22178353   PMID:22190020   PMID:22192441   PMID:22196954   PMID:22203929   PMID:22205174   PMID:22208681   PMID:22222005  
PMID:22241816   PMID:22257305   PMID:22260948   PMID:22267327   PMID:22267750   PMID:22267767   PMID:22277294   PMID:22284830   PMID:22291609   PMID:22296194   PMID:22297435   PMID:22306563  
PMID:22311704   PMID:22316266   PMID:22316276   PMID:22328138   PMID:22329434   PMID:22330622   PMID:22357713   PMID:22365588   PMID:22392590   PMID:22418747   PMID:22418989   PMID:22428468  
PMID:22430136   PMID:22435454   PMID:22437883   PMID:22444955   PMID:22446726   PMID:22449109   PMID:22457095   PMID:22459389   PMID:22464286   PMID:22467322   PMID:22474034   PMID:22490475  
PMID:22492993   PMID:22497530   PMID:22529527   PMID:22533665   PMID:22545649   PMID:22547903   PMID:22552174   PMID:22554299   PMID:22556030   PMID:22558327   PMID:22562290   PMID:22569431  
PMID:22569435   PMID:22570140   PMID:22576068   PMID:22580582   PMID:22588996   PMID:22592028   PMID:22607374   PMID:22614460   PMID:22617158   PMID:22641545   PMID:22642594   PMID:22645408  
PMID:22672862   PMID:22676422   PMID:22681496   PMID:22683644   PMID:22685243   PMID:22685586   PMID:22704860   PMID:22732721   PMID:22748017   PMID:22750226   PMID:22763479   PMID:22780440  
PMID:22783580   PMID:22783989   PMID:22796263   PMID:22801596   PMID:22813435   PMID:22813921   PMID:22816656   PMID:22821639   PMID:22828776   PMID:22832641   PMID:22836155   PMID:22843654  
PMID:22847196   PMID:22857740   PMID:22867744   PMID:22869540   PMID:22875408   PMID:22875596   PMID:22884413   PMID:22886358   PMID:22901456   PMID:22906275   PMID:22906998   PMID:22909410  
PMID:22911253   PMID:22912790   PMID:22914173   PMID:22918393   PMID:22939635   PMID:22949303   PMID:22957001   PMID:22976070   PMID:22982460   PMID:22989605   PMID:23013513   PMID:23026925  
PMID:23046580   PMID:23049543   PMID:23066418   PMID:23078984   PMID:23087143   PMID:23087294   PMID:23104422   PMID:23111890   PMID:23116190   PMID:23116196   PMID:23124693   PMID:23125484  
PMID:23126320   PMID:23132698   PMID:23139417   PMID:23141922   PMID:23151405   PMID:23151748   PMID:23157807   PMID:23158132   PMID:23159256   PMID:23166385   PMID:23170819   PMID:23182717  
PMID:23197238   PMID:23197841   PMID:23206444   PMID:23212397   PMID:23212764   PMID:23220502   PMID:23221172   PMID:23224322   PMID:23225486   PMID:23228375   PMID:23241067   PMID:23254637  
PMID:23254959   PMID:23257175   PMID:23257395   PMID:23263911   PMID:23266263   PMID:23270673   PMID:23272049   PMID:23274882   PMID:23277135   PMID:23285029   PMID:23288467   PMID:23306163  
PMID:23343124   PMID:23361365   PMID:23367494   PMID:23375121   PMID:23375154   PMID:23376485   PMID:23379491   PMID:23383155   PMID:23392788   PMID:23393371   PMID:23397258   PMID:23399387  
PMID:23401350   PMID:23409097   PMID:23411851   PMID:23425215   PMID:23427015   PMID:23428789   PMID:23434327   PMID:23440541   PMID:23450030   PMID:23463453   PMID:23468212   PMID:23484158  
PMID:23492986   PMID:23494263   PMID:23515055   PMID:23516493   PMID:23518675   PMID:23527487   PMID:23535585   PMID:23539615   PMID:23544079   PMID:23547018   PMID:23575330   PMID:23576062  
PMID:23578742   PMID:23579782   PMID:23591413   PMID:23592000   PMID:23592127   PMID:23604041   PMID:23618082   PMID:23624671   PMID:23627410   PMID:23635436   PMID:23665253   PMID:23674518  
PMID:23684514   PMID:23688010   PMID:23688319   PMID:23692330   PMID:23697277   PMID:23698155   PMID:23702388   PMID:23716069   PMID:23724031   PMID:23724977   PMID:23725496   PMID:23729554  
PMID:23731527   PMID:23735372   PMID:23742758   PMID:23755178   PMID:23763486   PMID:23766379   PMID:23773138   PMID:23774275   PMID:23784529   PMID:23801460   PMID:23803251   PMID:23808014  
PMID:23813138   PMID:23813627   PMID:23813850   PMID:23828261   PMID:23835994   PMID:23836113   PMID:23844046   PMID:23852903   PMID:23857741   PMID:23867726   PMID:23875844   PMID:23887753  
PMID:23888317   PMID:23910616   PMID:23911413   PMID:23932860   PMID:23935961   PMID:23940726   PMID:23941472   PMID:23950953   PMID:23953546   PMID:23955082   PMID:23955613   PMID:23957657  
PMID:23959959   PMID:23959964   PMID:23968978   PMID:23977389   PMID:23978367   PMID:23980698   PMID:23981122   PMID:23985781   PMID:23991042   PMID:24005810   PMID:24007461   PMID:24010569  
PMID:24012914   PMID:24016543   PMID:24025976   PMID:24028935   PMID:24039853   PMID:24045283   PMID:24051868   PMID:24055729   PMID:24057344   PMID:24060429   PMID:24061501   PMID:24072269  
PMID:24072695   PMID:24074718   PMID:24084772   PMID:24085705   PMID:24095158   PMID:24097561   PMID:24102179   PMID:24102428   PMID:24105071   PMID:24126766   PMID:24130817   PMID:24135623  
PMID:24141169   PMID:24146936   PMID:24148787   PMID:24150223   PMID:24152229   PMID:24163955   PMID:24164492   PMID:24197824   PMID:24204905   PMID:24206243   PMID:24209691   PMID:24217195  
PMID:24217304   PMID:24222149   PMID:24222151   PMID:24228880   PMID:24231564   PMID:24239465   PMID:24243751   PMID:24244755   PMID:24247217   PMID:24247268   PMID:24254894   PMID:24259949  
PMID:24262327   PMID:24266503   PMID:24286072   PMID:24289571   PMID:24290960   PMID:24300392   PMID:24305621   PMID:24312587   PMID:24313319   PMID:24338120   PMID:24339203   PMID:24342328  
PMID:24347428   PMID:24351805   PMID:24356040   PMID:24360158   PMID:24363360   PMID:24368157   PMID:24374086   PMID:24378957   PMID:24379064   PMID:24380782   PMID:24403485   PMID:24410968  
PMID:24418758   PMID:24422709   PMID:24434384   PMID:24440351   PMID:24446242   PMID:24451691   PMID:24456036   PMID:24457057   PMID:24470529   PMID:24474658   PMID:24501104   PMID:24505819  
PMID:24506399   PMID:24517733   PMID:24521195   PMID:24523037   PMID:24524956   PMID:24530944   PMID:24548663   PMID:24554512   PMID:24558466   PMID:24558995   PMID:24564178   PMID:24565000  
PMID:24568622   PMID:24572983   PMID:24574329   PMID:24574805   PMID:24577623   PMID:24587064   PMID:24587705   PMID:24588117   PMID:24602049   PMID:24603645   PMID:24610897   PMID:24611307  
PMID:24622110   PMID:24625581   PMID:24627113   PMID:24630704   PMID:24635486   PMID:24636767   PMID:24647324   PMID:24656623   PMID:24660532   PMID:24670724   PMID:24694904   PMID:24696367  
PMID:24709882   PMID:24711458   PMID:24715304   PMID:24716416   PMID:24716628   PMID:24719979   PMID:24751480   PMID:24761881   PMID:24762112   PMID:24763700   PMID:24771073   PMID:24784714  
PMID:24790070   PMID:24795153   PMID:24796336   PMID:24798783   PMID:24808122   PMID:24811768   PMID:24827394   PMID:24835352   PMID:24835491   PMID:24836084   PMID:24838548   PMID:24844401  
PMID:24861467   PMID:24862635   PMID:24867029   PMID:24877114   PMID:24878684   PMID:24884805   PMID:24885051   PMID:24886302   PMID:24889374   PMID:24894103   PMID:24905620   PMID:24909972  
PMID:24913743   PMID:24924697   PMID:24928303   PMID:24928820   PMID:24937391   PMID:24948846   PMID:24952865   PMID:24956415   PMID:24965144   PMID:24969183   PMID:24969579   PMID:24974939  
PMID:24975656   PMID:24980707   PMID:24981713   PMID:24982116   PMID:24989682   PMID:24991031   PMID:24991721   PMID:25005858   PMID:25014522   PMID:25019352   PMID:25019591   PMID:25027167  
PMID:25027406   PMID:25043606   PMID:25070472   PMID:25070920   PMID:25078741   PMID:25079465   PMID:25081365   PMID:25105149   PMID:25123708   PMID:25132319   PMID:25136879   PMID:25145487  
PMID:25153416   PMID:25155623   PMID:25158036   PMID:25159654   PMID:25170663   PMID:25171778   PMID:25172166   PMID:25172979   PMID:25185422   PMID:25187575   PMID:25190127   PMID:25194730  
PMID:25222341   PMID:25230678   PMID:25260501   PMID:25266886   PMID:25273597   PMID:25277876   PMID:25286759   PMID:25296733   PMID:25299643   PMID:25306212   PMID:25314633   PMID:25329583  
PMID:25331535   PMID:25335739   PMID:25336462   PMID:25338987   PMID:25340395   PMID:25344970   PMID:25351965   PMID:25354266   PMID:25359432   PMID:25364078   PMID:25373740   PMID:25380841  
PMID:25392126   PMID:25411996   PMID:25416956   PMID:25426616   PMID:25426618   PMID:25433580   PMID:25436282   PMID:25436306   PMID:25449469   PMID:25460573   PMID:25463127   PMID:25467832  
PMID:25470633   PMID:25491620   PMID:25491624   PMID:25492251   PMID:25501922   PMID:25526927   PMID:25542737   PMID:25548320   PMID:25552313   PMID:25561281   PMID:25594234   PMID:25596909  
PMID:25601896   PMID:25603415   PMID:25603416   PMID:25604866   PMID:25613713   PMID:25618827   PMID:25636121   PMID:25651710   PMID:25651728   PMID:25651736   PMID:25658658   PMID:25682033  
PMID:25690104   PMID:25691533   PMID:25697203   PMID:25708781   PMID:25711952   PMID:25735198   PMID:25748492   PMID:25768928   PMID:25781366   PMID:25804556   PMID:25804952   PMID:25809368  
PMID:25814554   PMID:25817719   PMID:25821796   PMID:25822970   PMID:25827033   PMID:25829237   PMID:25832424   PMID:25854969   PMID:25855626   PMID:25856390   PMID:25864110   PMID:25874450  
PMID:25879749   PMID:25886998   PMID:25887518   PMID:25889630   PMID:25893544   PMID:25903822   PMID:25911075   PMID:25913621   PMID:25916049   PMID:25916065   PMID:25917100   PMID:25921150  
PMID:25922147   PMID:25926728   PMID:25935447   PMID:25941076   PMID:25957466   PMID:25963492   PMID:25970741   PMID:25974422   PMID:25982004   PMID:25986475   PMID:25987110   PMID:25990058  
PMID:25991421   PMID:25993353   PMID:25994228   PMID:25999661   PMID:26013044   PMID:26013149   PMID:26018813   PMID:26021292   PMID:26025192   PMID:26026118   PMID:26026588   PMID:26032849  
PMID:26033244   PMID:26043285   PMID:26044709   PMID:26046926   PMID:26058824   PMID:26060162   PMID:26063371   PMID:26077975   PMID:26079659   PMID:26080030   PMID:26088452   PMID:26096228  
PMID:26098322   PMID:26106052   PMID:26106150   PMID:26125767   PMID:26130785   PMID:26133301   PMID:26146067   PMID:26161003   PMID:26177029   PMID:26200604   PMID:26202142   PMID:26208640  
PMID:26218286   PMID:26222902   PMID:26226010   PMID:26229958   PMID:26232108   PMID:26241961   PMID:26247033   PMID:26256894   PMID:26260869   PMID:26266345   PMID:26271020   PMID:26278889  
PMID:26280117   PMID:26283879   PMID:26299079   PMID:26302926   PMID:26308525   PMID:26310275   PMID:26339423   PMID:26339617   PMID:26348353   PMID:26351389   PMID:26354559   PMID:26357470  
PMID:26390126   PMID:26391131   PMID:26396066   PMID:26425690   PMID:26434105   PMID:26451493   PMID:26453329   PMID:26456189   PMID:26458341   PMID:26473826   PMID:26474473   PMID:26480896  
PMID:26497374   PMID:26499778   PMID:26525102   PMID:26530188   PMID:26539647   PMID:26559885   PMID:26566216   PMID:26576922   PMID:26579988   PMID:26607724   PMID:26625129   PMID:26628300  
PMID:26635226   PMID:26643974   PMID:26644355   PMID:26665555   PMID:26698253   PMID:26700933   PMID:26718567   PMID:26721294   PMID:26728665   PMID:26752692   PMID:26771969   PMID:26791379  
PMID:26810014   PMID:26817828   PMID:26822196   PMID:26824043   PMID:26832367   PMID:26833068   PMID:26849008   PMID:26850725   PMID:26857687   PMID:26857805   PMID:26862048   PMID:26871443  
PMID:26874351   PMID:26884133   PMID:26884882   PMID:26891844   PMID:26894972   PMID:26898490   PMID:26910885   PMID:26912098   PMID:26919511   PMID:26921743   PMID:26922829   PMID:26933237  
PMID:26933799   PMID:26940485   PMID:26942752   PMID:26951183   PMID:26963617   PMID:26984957   PMID:26996570   PMID:26999249   PMID:27016573   PMID:27022914   PMID:27023106   PMID:27044366  
PMID:27049070   PMID:27056089   PMID:27061480   PMID:27091202   PMID:27093616   PMID:27095586   PMID:27096761   PMID:27105046   PMID:27121518   PMID:27135541   PMID:27150021   PMID:27164124  
PMID:27173614   PMID:27177774   PMID:27182730   PMID:27235695   PMID:27237221   PMID:27266621   PMID:27268644   PMID:27271159   PMID:27276070   PMID:27287260   PMID:27294662   PMID:27295905  
PMID:27311068   PMID:27312194   PMID:27312245   PMID:27313400   PMID:27323094   PMID:27333717   PMID:27359302   PMID:27364992   PMID:27385219   PMID:27388709   PMID:27389865   PMID:27444618  
PMID:27448592   PMID:27470679   PMID:27476050   PMID:27485861   PMID:27487299   PMID:27492718   PMID:27493807   PMID:27496931   PMID:27507606   PMID:27560308   PMID:27562034   PMID:27566075  
PMID:27579325   PMID:27580453   PMID:27585799   PMID:27608842   PMID:27619398   PMID:27622678   PMID:27630314   PMID:27633999   PMID:27638106   PMID:27643980   PMID:27650825   PMID:27663770  
PMID:27696432   PMID:27697536   PMID:27705004   PMID:27706779   PMID:27733196   PMID:27738330   PMID:27741061   PMID:27752903   PMID:27760719   PMID:27778189   PMID:27784852   PMID:27788529  
PMID:27799762   PMID:27808345   PMID:27809289   PMID:27823974   PMID:27863333   PMID:27867158   PMID:27878726   PMID:27882931   PMID:27884320   PMID:27900989   PMID:27915263   PMID:27916142  
PMID:27941423   PMID:27984485   PMID:27994452   PMID:28003224   PMID:28055283   PMID:28079845   PMID:28095127   PMID:28096464   PMID:28102774   PMID:28110894   PMID:28119309   PMID:28121954  
PMID:28125601   PMID:28128229   PMID:28128312   PMID:28129995   PMID:28132052   PMID:28138990   PMID:28143876   PMID:28167277   PMID:28181636   PMID:28183448   PMID:28185443   PMID:28207502  
PMID:28209200   PMID:28218562   PMID:28222033   PMID:28225631   PMID:28228104   PMID:28247593   PMID:28262856   PMID:28284664   PMID:28287042   PMID:28299332   PMID:28300543   PMID:28302952  
PMID:28321403   PMID:28336391   PMID:28350535   PMID:28351163   PMID:28358790   PMID:28368304   PMID:28393357   PMID:28432705   PMID:28434325   PMID:28454850   PMID:28456936   PMID:28489774  
PMID:28489776   PMID:28498565   PMID:28506639   PMID:28514442   PMID:28514756   PMID:28533443   PMID:28535403   PMID:28540883   PMID:28549956   PMID:28550906   PMID:28566480   PMID:28567557  
PMID:28577953   PMID:28585145   PMID:28586387   PMID:28616918   PMID:28618965   PMID:28619036   PMID:28620227   PMID:28622356   PMID:28624829   PMID:28666785   PMID:28667300   PMID:28676043  
PMID:28686695   PMID:28687081   PMID:28693979   PMID:28706007   PMID:28716139   PMID:28721654   PMID:28724840   PMID:28728065   PMID:28733795   PMID:28734805   PMID:28739188   PMID:28750115  
PMID:28770703   PMID:28778585   PMID:28801369   PMID:28801571   PMID:28813455   PMID:28823374   PMID:28826799   PMID:28838917   PMID:28846105   PMID:28867284   PMID:28876618   PMID:28898742  
PMID:28901315   PMID:28918433   PMID:28920169   PMID:28937461   PMID:28942872   PMID:28945626   PMID:28946036   PMID:28982904   PMID:29024426   PMID:29026382   PMID:29043995   PMID:29066452  
PMID:29066453   PMID:29078256   PMID:29080691   PMID:29111402   PMID:29117798   PMID:29118378   PMID:29172154   PMID:29181397   PMID:29187474   PMID:29198208   PMID:29202702   PMID:29223510  
PMID:29233917   PMID:29243511   PMID:29254299   PMID:29257244   PMID:29298663   PMID:29306175   PMID:29317123   PMID:29325799   PMID:29351749   PMID:29374201   PMID:29379005   PMID:29380890  
PMID:29384797   PMID:29385406   PMID:29396658   PMID:29402404   PMID:29402657   PMID:29426269   PMID:29430983   PMID:29436255   PMID:29439678   PMID:29452544   PMID:29482547   PMID:29491077  
PMID:29499122   PMID:29502925   PMID:29549910   PMID:29552019   PMID:29556849   PMID:29556980   PMID:29577860   PMID:29581482   PMID:29630649   PMID:29635941   PMID:29644527   PMID:29656292  
PMID:29668751   PMID:29674505   PMID:29687414   PMID:29701260   PMID:29715162   PMID:29718222   PMID:29792017   PMID:29854731   PMID:29855349   PMID:29857573   PMID:29861471   PMID:29878111  
PMID:29895445   PMID:29895893   PMID:29910808   PMID:29921457   PMID:29927991   PMID:29932219   PMID:29954070   PMID:29991774   PMID:29992240   PMID:30015514   PMID:30021884   PMID:30026044  
PMID:30030926   PMID:30031673   PMID:30056003   PMID:30059659   PMID:30094934   PMID:30119141   PMID:30137576   PMID:30138391   PMID:30143494   PMID:30143887   PMID:30154790   PMID:30158031  
PMID:30178394   PMID:30237086   PMID:30259282   PMID:30268067   PMID:30268671   PMID:30273893   PMID:30278950   PMID:30280549   PMID:30297724   PMID:30298649   PMID:30336524   PMID:30338815  
PMID:30352089   PMID:30353300   PMID:30364161   PMID:30377862   PMID:30407267   PMID:30408622   PMID:30409736   PMID:30451721   PMID:30451748   PMID:30456501   PMID:30459761   PMID:30463115  
PMID:30483265   PMID:30533423   PMID:30541988   PMID:30562090   PMID:30591494   PMID:30600958   PMID:30607764   PMID:30610790   PMID:30619374   PMID:30630560   PMID:30632650   PMID:30641758  
PMID:30656987   PMID:30718369   PMID:30777536   PMID:30794227   PMID:30810658   PMID:30862180   PMID:30874448   PMID:30882594   PMID:30888211   PMID:30903199   PMID:30912862   PMID:30952746  
PMID:30952767   PMID:30961517   PMID:30976022   PMID:31016379   PMID:31036824   PMID:31074311   PMID:31078361   PMID:31091356   PMID:31092463   PMID:31118224   PMID:31135903   PMID:31138314  
PMID:31140334   PMID:31141720   PMID:31142628   PMID:31186149   PMID:31195938   PMID:31267817   PMID:31281843   PMID:31299414   PMID:31302740   PMID:31331321   PMID:31336145   PMID:31342266  
PMID:31350553   PMID:31356989   PMID:31358306   PMID:31377747   PMID:31396293   PMID:31399624   PMID:31410012   PMID:31414767   PMID:31416781   PMID:31418936   PMID:31469126   PMID:31471424  
PMID:31494638   PMID:31500937   PMID:31511566   PMID:31584351   PMID:31599438   PMID:31608892   PMID:31622379   PMID:31642812   PMID:31645641   PMID:31666656   PMID:31691187   PMID:31692152  
PMID:31694563   PMID:31721795   PMID:31768828   PMID:31769325   PMID:31798002   PMID:31810721   PMID:31875617   PMID:31907827   PMID:31945605   PMID:31962161   PMID:31971480   PMID:31971845  
PMID:31985315   PMID:31996746   PMID:32000385   PMID:32022122   PMID:32076032   PMID:32166607   PMID:32185759   PMID:32189313   PMID:32200354   PMID:32205702   PMID:32222842   PMID:32234939  
PMID:32238865   PMID:32253920   PMID:32281668   PMID:32283288   PMID:32286427   PMID:32303612   PMID:32306287   PMID:32307906   PMID:32311164   PMID:32329054   PMID:32354366   PMID:32354388  
PMID:32359394   PMID:32400228   PMID:32402651   PMID:32416678   PMID:32431027   PMID:32434368   PMID:32437868   PMID:32470505   PMID:32477370   PMID:32503410   PMID:32507340   PMID:32507777  
PMID:32507953   PMID:32511972   PMID:32513543   PMID:32531257   PMID:32534387   PMID:32538747   PMID:32538759   PMID:32543756   PMID:32545848   PMID:32561398   PMID:32564084   PMID:32577988  
PMID:32578463   PMID:32581042   PMID:32602547   PMID:32620647   PMID:32639009   PMID:32643402   PMID:32645077   PMID:32654566   PMID:32671825   PMID:32690576   PMID:32715769   PMID:32715784  
PMID:32720219   PMID:32724277   PMID:32735982   PMID:32745312   PMID:32755646   PMID:32804580   PMID:32822785   PMID:32837031   PMID:32840917   PMID:32841297   PMID:32873770   PMID:32892646  
PMID:32895405   PMID:32937187   PMID:32940549   PMID:32952850   PMID:32959132   PMID:32963635   PMID:32970496   PMID:32988897   PMID:33080689   PMID:33081810   PMID:33084992   PMID:33089708  
PMID:33116232   PMID:33130259   PMID:33145348   PMID:33161875   PMID:33188660   PMID:33190115   PMID:33198782   PMID:33208875   PMID:33247320   PMID:33296257   PMID:33309637   PMID:33321161  
PMID:33326672   PMID:33326704   PMID:33334321   PMID:33345630   PMID:33348178   PMID:33359278   PMID:33371718   PMID:33385735   PMID:33392755   PMID:33415152   PMID:33415573   PMID:33479472  
PMID:33485312   PMID:33488610   PMID:33527329   PMID:33538655   PMID:33542341   PMID:33564690   PMID:33577066   PMID:33584722   PMID:33609292   PMID:33615804   PMID:33624037   PMID:33624897  
PMID:33635872   PMID:33649360   PMID:33650305   PMID:33657762   PMID:33663300   PMID:33668004   PMID:33670593   PMID:33679775   PMID:33682035   PMID:33707594   PMID:33709785   PMID:33714740  
PMID:33722242   PMID:33740951   PMID:33750215   PMID:33767361   PMID:33790888   PMID:33796111   PMID:33799436   PMID:33849839   PMID:33861985   PMID:33902353   PMID:33906709   PMID:33932814  
PMID:33952490   PMID:33961781   PMID:33973261   PMID:33985349   PMID:34019244   PMID:34049444   PMID:34052362   PMID:34091325   PMID:34153093   PMID:34157178   PMID:34160712   PMID:34170079  
PMID:34180324   PMID:34227058   PMID:34234877   PMID:34237966   PMID:34242184   PMID:34252128   PMID:34273357   PMID:34292580   PMID:34340611   PMID:34367126   PMID:34391864   PMID:34439862  
PMID:34447388   PMID:34449869   PMID:34468926   PMID:34493377   PMID:34497035   PMID:34506994   PMID:34507654   PMID:34538509   PMID:34559143   PMID:34611064   PMID:34631892   PMID:34636117  
PMID:34671810   PMID:34673211   PMID:34680168   PMID:34686516   PMID:34699035   PMID:34769069   PMID:34794144   PMID:34824534   PMID:34856793   PMID:34879502   PMID:34887479   PMID:34909891  
PMID:34909913   PMID:34910426   PMID:34915091   PMID:34920091   PMID:34930392   PMID:34933739   PMID:34975846   PMID:35058385   PMID:35062811   PMID:35066901   PMID:35112776   PMID:35113419  
PMID:35192610   PMID:35197177   PMID:35242241   PMID:35248663   PMID:35275462   PMID:35296708   PMID:35357792   PMID:35379263   PMID:35379317   PMID:35432388   PMID:35437619   PMID:35459240  
PMID:35614177   PMID:35614388   PMID:35739525   PMID:35758963   PMID:35784528   PMID:35792017   PMID:35821191   PMID:35874670   PMID:35896901   PMID:35907785   PMID:36062874   PMID:36111938  
PMID:36117174   PMID:36162594   PMID:36237420   PMID:36346047   PMID:36355253   PMID:36376304   PMID:36430593   PMID:36470180   PMID:36479675   PMID:36589832   PMID:36609091   PMID:36809395  
PMID:36834488   PMID:36877030   PMID:36949309   PMID:36976377   PMID:36977496   PMID:36996866   PMID:37069442   PMID:37081535   PMID:37087459   PMID:37148961   PMID:37150315   PMID:37158153  
PMID:37195992   PMID:37197571   PMID:37221147   PMID:37235788   PMID:37239434   PMID:37244790   PMID:37329537   PMID:37348803   PMID:37396735   PMID:37406418   PMID:37443809   PMID:37462305  
PMID:37481511   PMID:37493001   PMID:37534674   PMID:37568161   PMID:37640989   PMID:37665407   PMID:37720216   PMID:37777916   PMID:37801334   PMID:37833739   PMID:37844994   PMID:37852738  
PMID:37905346   PMID:37906712   PMID:37943853   PMID:38063118   PMID:38077346   PMID:38215120   PMID:38235562   PMID:38332001   PMID:38439017   PMID:38566874   PMID:38627621   PMID:38634265  
PMID:38785970   PMID:38947332   PMID:39240968   PMID:39280318  


Genomics

Comparative Map Data
CRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381159,712,289 - 159,714,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1159,712,289 - 159,714,589 (-)EnsemblGRCh38hg38GRCh38
GRCh371159,682,079 - 159,684,379 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,948,703 - 157,951,003 (-)NCBINCBI36Build 36hg18NCBI36
Build 341156,495,152 - 156,497,452NCBI
Celera1132,750,525 - 132,752,817 (-)NCBICelera
Cytogenetic Map1q23.2NCBI
HuRef1131,038,539 - 131,040,831 (-)NCBIHuRef
CHM1_11161,076,594 - 161,078,894 (-)NCBICHM1_1
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBIT2T-CHM13v2.0
Crp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,525,623 - 172,527,533 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1172,525,622 - 172,660,598 (+)EnsemblGRCm39 Ensembl
GRCm381172,698,056 - 172,699,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,698,055 - 172,833,031 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,628,187 - 174,630,097 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361174,534,741 - 174,536,635 (+)NCBIMGSCv36mm8
Celera1175,548,254 - 175,550,142 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.13NCBI
Crp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81387,694,062 - 87,695,978 (+)NCBIGRCr8
mRatBN7.21385,135,384 - 85,175,178 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1385,124,977 - 85,175,178 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1387,664,967 - 87,666,915 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01389,065,246 - 89,067,190 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01386,249,976 - 86,251,928 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01391,080,448 - 91,081,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,054,974 - 91,093,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,599,418 - 95,600,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,702,243 - 88,703,153 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11388,891,058 - 88,892,928 (+)NCBI
Celera1384,770,843 - 84,771,753 (+)NCBICelera
Cytogenetic Map13q24NCBI
CRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2190,140,428 - 90,143,900 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1189,880,463 - 89,883,937 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01135,062,102 - 135,064,402 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11138,858,353 - 138,860,652 (-)NCBIpanpan1.1PanPan1.1panPan2
CRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,396,787 - 22,398,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,396,263 - 22,399,166 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,473,724 - 22,475,116 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03822,519,785 - 22,521,176 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3822,519,714 - 22,522,146 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13822,286,369 - 22,287,757 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03822,818,770 - 22,820,163 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03823,230,160 - 23,231,548 (+)NCBIUU_Cfam_GSD_1.0
Crp
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050585,866,551 - 5,870,192 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936740883,272 - 890,606 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936740885,855 - 888,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,793,350 - 90,805,218 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,793,361 - 90,801,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,764,964 - 98,772,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CRP
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1204,232,262 - 4,235,826 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl204,232,913 - 4,235,377 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660383,340,251 - 3,342,511 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,531,571 - 1,533,804 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247941,531,555 - 1,533,804 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CRP
22 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q23.2-24.1(chr1:159479887-166895086)x1 copy number loss See cases [RCV000051172] Chr1:159479887..166895086 [GRCh38]
Chr1:159449677..166864323 [GRCh37]
Chr1:157716301..165130947 [NCBI36]
Chr1:1q23.2-24.1		 pathogenic
GRCh38/hg38 1q23.1-25.1(chr1:157747246-176021247)x3 copy number gain See cases [RCV000051854] Chr1:157747246..176021247 [GRCh38]
Chr1:157717036..175990383 [GRCh37]
Chr1:155983660..174257006 [NCBI36]
Chr1:1q23.1-25.1		 pathogenic
GRCh38/hg38 1q23.1-23.3(chr1:156664483-160727411)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051851]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051851]|See cases [RCV000051851] Chr1:156664483..160727411 [GRCh38]
Chr1:156634275..160697201 [GRCh37]
Chr1:154900899..158963825 [NCBI36]
Chr1:1q23.1-23.3		 pathogenic
NM_000567.2(CRP):c.31A>C (p.Thr11Pro) single nucleotide variant Malignant melanoma [RCV000064246] Chr1:159714455 [GRCh38]
Chr1:159684245 [GRCh37]
Chr1:157950869 [NCBI36]
Chr1:1q23.2		 not provided
GRCh38/hg38 1q21.2-25.2(chr1:149854269-180267197)x3 copy number gain See cases [RCV000143515] Chr1:149854269..180267197 [GRCh38]
Chr1:149825831..180236332 [GRCh37]
Chr1:148092455..178502955 [NCBI36]
Chr1:1q21.2-25.2		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_000567.3(CRP):c.576C>G (p.Ile192Met) single nucleotide variant not specified [RCV004299255] Chr1:159713624 [GRCh38]
Chr1:159683414 [GRCh37]
Chr1:1q23.2		 uncertain significance
GRCh37/hg19 1q23.1-24.2(chr1:157321299-167391423)x1 copy number loss not provided [RCV000848773] Chr1:157321299..167391423 [GRCh37]
Chr1:1q23.1-24.2		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44		 pathogenic
NM_000567.3(CRP):c.636G>T (p.Val212=) single nucleotide variant not provided [RCV000929232] Chr1:159713564 [GRCh38]
Chr1:159683354 [GRCh37]
Chr1:1q23.2		 likely benign
NM_000567.3(CRP):c.360C>T (p.Ser120=) single nucleotide variant not provided [RCV000900681] Chr1:159713840 [GRCh38]
Chr1:159683630 [GRCh37]
Chr1:1q23.2		 likely benign
NM_000567.3(CRP):c.105T>G (p.Thr35=) single nucleotide variant not provided [RCV000880978] Chr1:159714095 [GRCh38]
Chr1:159683885 [GRCh37]
Chr1:1q23.2		 benign
NM_000567.3(CRP):c.129G>A (p.Pro43=) single nucleotide variant not provided [RCV000974601] Chr1:159714071 [GRCh38]
Chr1:159683861 [GRCh37]
Chr1:1q23.2		 benign
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44		 uncertain significance
NM_000567.3(CRP):c.176C>T (p.Thr59Met) single nucleotide variant CRP-related disorder [RCV003918877]|not provided [RCV001355473] Chr1:159714024 [GRCh38]
Chr1:159714024..159714025 [GRCh38]
Chr1:159683814 [GRCh37]
Chr1:159683814..159683815 [GRCh37]
Chr1:1q23.2		 likely benign|uncertain significance
NC_000001.10:g.(?_158581054)_(162750036_?)dup duplication Autoimmune interstitial lung disease-arthritis syndrome [RCV001918952]|not provided [RCV001918953] Chr1:158581054..162750036 [GRCh37]
Chr1:1q23.1-23.3		 uncertain significance|no classifications from unflagged records
NM_000567.3(CRP):c.*1082G>A single nucleotide variant Inflammation [RCV002259422] Chr1:159712443 [GRCh38]
Chr1:159682233 [GRCh37]
Chr1:1q23.2		 uncertain significance
GRCh37/hg19 1q23.2(chr1:159600385-159715180)x1 copy number loss not provided [RCV002474894] Chr1:159600385..159715180 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.619G>C (p.Ala207Pro) single nucleotide variant not specified [RCV004241197] Chr1:159713581 [GRCh38]
Chr1:159683371 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.635T>C (p.Val212Ala) single nucleotide variant not specified [RCV004091986] Chr1:159713565 [GRCh38]
Chr1:159683355 [GRCh37]
Chr1:1q23.2		 likely benign
NM_000567.3(CRP):c.496G>A (p.Gly166Arg) single nucleotide variant not specified [RCV004121295] Chr1:159713704 [GRCh38]
Chr1:159683494 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.212C>G (p.Ser71Trp) single nucleotide variant not specified [RCV004154188] Chr1:159713988 [GRCh38]
Chr1:159683778 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.646G>A (p.Val216Met) single nucleotide variant not specified [RCV004126140] Chr1:159713554 [GRCh38]
Chr1:159683344 [GRCh37]
Chr1:1q23.2		 uncertain significance
GRCh37/hg19 1q23.1-23.3(chr1:158001058-162858285)x1 copy number loss not provided [RCV003483944] Chr1:158001058..162858285 [GRCh37]
Chr1:1q23.1-23.3		 likely pathogenic
NM_000567.3(CRP):c.339C>T (p.His113=) single nucleotide variant not provided [RCV003409179] Chr1:159713861 [GRCh38]
Chr1:159683651 [GRCh37]
Chr1:1q23.2		 likely benign
NM_000567.3(CRP):c.149C>G (p.Ala50Gly) single nucleotide variant not specified [RCV004369955] Chr1:159714051 [GRCh38]
Chr1:159683841 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.212C>T (p.Ser71Leu) single nucleotide variant not specified [RCV004369956] Chr1:159713988 [GRCh38]
Chr1:159683778 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.302T>C (p.Leu101Ser) single nucleotide variant not specified [RCV004369957] Chr1:159713898 [GRCh38]
Chr1:159683688 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.521T>C (p.Ile174Thr) single nucleotide variant CRP-related disorder [RCV003933910] Chr1:159713679 [GRCh38]
Chr1:159683469 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.357G>C (p.Glu119Asp) single nucleotide variant CRP-related disorder [RCV003982728] Chr1:159713843 [GRCh38]
Chr1:159683633 [GRCh37]
Chr1:1q23.2		 uncertain significance
NM_000567.3(CRP):c.134C>T (p.Thr45Met) single nucleotide variant CRP-related disorder [RCV004758549] Chr1:159714066 [GRCh38]
Chr1:159683856 [GRCh37]
Chr1:1q23.2		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2538
Count of miRNA genes:796
Interacting mature miRNAs:901
Transcripts:ENST00000255030, ENST00000343919, ENST00000368110, ENST00000368111, ENST00000368112, ENST00000437342, ENST00000473196, ENST00000489317
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
596956916GWAS1076435_HC-reactive protein measurement QTL GWAS1076435 (human)1e-48C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159713648159713649Human
1357381BW57_HBody weight QTL 57 (human)10.0001Body weightfat free mass after exercise training1140630236166630236Human
597099445GWAS1195519_HC-reactive protein measurement QTL GWAS1195519 (human)2e-157C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159712443159712444Human
597116658GWAS1212732_HC-reactive protein measurement QTL GWAS1212732 (human)5e-23C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159714026159714027Human
597147505GWAS1243579_Hlow density lipoprotein cholesterol measurement QTL GWAS1243579 (human)2e-205low density lipoprotein cholesterol measurementblood low density lipoprotein cholesterol level (CMO:0000053)1159712443159712444Human
597115793GWAS1211867_HC-reactive protein measurement QTL GWAS1211867 (human)2e-200C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159713648159713649Human
597116657GWAS1212731_HC-reactive protein measurement QTL GWAS1212731 (human)6e-09C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159714007159714008Human
597222863GWAS1318937_HC-reactive protein measurement QTL GWAS1318937 (human)4e-287C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159714024159714025Human
597232625GWAS1328699_Herythropoetin measurement QTL GWAS1328699 (human)4e-23erythropoetin measurement1159713301159713302Human
597250608GWAS1346682_HC-reactive protein measurement QTL GWAS1346682 (human)1e-48C-reactive protein measurementblood C-reactive protein level (CMO:0003160)1159713648159713649Human
597342150GWAS1438224_Hcomplex trait QTL GWAS1438224 (human)1e-24complex trait1159713648159713649Human
597341940GWAS1438014_Hcomplex trait QTL GWAS1438014 (human)5e-35complex trait1159712443159712444Human

Markers in Region
D1S3335  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,085 - 159,682,407UniSTSGRCh37
Build 361157,948,709 - 157,949,031RGDNCBI36
Celera1132,750,531 - 132,750,853RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,545 - 131,038,867UniSTS
GeneMap99-GB4 RH Map1587.74UniSTS
Whitehead-YAC Contig Map1 UniSTS
NCBI RH Map11436.5UniSTS
RH11610  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,143 - 159,682,280UniSTSGRCh37
Build 361157,948,767 - 157,948,904RGDNCBI36
Celera1132,750,589 - 132,750,726RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,603 - 131,038,740UniSTS
GeneMap99-GB4 RH Map1574.66UniSTS
NCBI RH Map11436.5UniSTS
G54038  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,155 - 159,682,306UniSTSGRCh37
Build 361157,948,779 - 157,948,930RGDNCBI36
Celera1132,750,601 - 132,750,752RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,615 - 131,038,766UniSTS
PMC311069P8  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,194 - 159,682,273UniSTSGRCh37
Build 361157,948,818 - 157,948,897RGDNCBI36
Celera1132,750,640 - 132,750,719RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,654 - 131,038,733UniSTS
PMC98081P1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,683,463 - 159,683,784UniSTSGRCh37
Build 361157,950,087 - 157,950,408RGDNCBI36
Celera1132,751,909 - 132,752,230RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,039,923 - 131,040,244UniSTS
PMC98081P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,683,329 - 159,683,922UniSTSGRCh37
Build 361157,949,953 - 157,950,546RGDNCBI36
Celera1132,751,775 - 132,752,368RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,039,789 - 131,040,382UniSTS
CRP_559  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,384 - 159,683,084UniSTSGRCh37
Build 361157,949,008 - 157,949,708RGDNCBI36
Celera1132,750,830 - 132,751,530RGD
HuRef1131,038,844 - 131,039,544UniSTS
GDB:190880  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,683,978 - 159,684,116UniSTSGRCh37
Build 361157,950,602 - 157,950,740RGDNCBI36
Celera1132,752,424 - 132,752,554RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,040,438 - 131,040,568UniSTS
Marshfield Genetic Map1165.62UniSTS
WIAF-2117  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,130 - 159,682,357UniSTSGRCh37
Build 361157,948,754 - 157,948,981RGDNCBI36
Celera1132,750,576 - 132,750,803RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,590 - 131,038,817UniSTS
GeneMap99-GB4 RH Map1588.98UniSTS
RH18109  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,514 - 159,682,748UniSTSGRCh37
Build 361157,949,138 - 157,949,372RGDNCBI36
Celera1132,750,960 - 132,751,194RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,974 - 131,039,208UniSTS
GeneMap99-GB4 RH Map1574.66UniSTS
NCBI RH Map11436.5UniSTS
RH11065  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,683,281 - 159,683,541UniSTSGRCh37
Build 361157,949,905 - 157,950,165RGDNCBI36
Celera1132,751,727 - 132,751,987RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,039,741 - 131,040,001UniSTS
GeneMap99-GB4 RH Map1587.43UniSTS
NCBI RH Map11436.5UniSTS
D1S2384  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371159,682,467 - 159,682,815UniSTSGRCh37
Build 361157,949,091 - 157,949,439RGDNCBI36
Celera1132,750,913 - 132,751,261RGD
Cytogenetic Map1q23.2UniSTS
HuRef1131,038,927 - 131,039,275UniSTS
Whitehead-YAC Contig Map1 UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1176 1952 2311 1795 3387 1517 1889 2 593 975 444 1713 5191 4908 1 2686 605 1377 1217 152

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_013007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329057 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001329058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001382703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF442818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF449713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI609949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL445528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC070257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG533281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG618397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG618967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA514417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  K00518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC276934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC276935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC276936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC276937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LC276938 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M11880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35163 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X56692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000255030   ⟹   ENSP00000255030
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,289 - 159,714,589 (-)Ensembl
Ensembl Acc Id: ENST00000368110   ⟹   ENSP00000357091
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,563 - 159,714,589 (-)Ensembl
Ensembl Acc Id: ENST00000368111   ⟹   ENSP00000357092
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,504 - 159,714,589 (-)Ensembl
Ensembl Acc Id: ENST00000368112   ⟹   ENSP00000357093
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,410 - 159,714,589 (-)Ensembl
Ensembl Acc Id: ENST00000437342   ⟹   ENSP00000402788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,293 - 159,714,589 (-)Ensembl
Ensembl Acc Id: ENST00000473196
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,291 - 159,713,767 (-)Ensembl
Ensembl Acc Id: ENST00000489317
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1159,712,535 - 159,714,080 (-)Ensembl
RefSeq Acc Id: NM_000567   ⟹   NP_000558
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381159,712,289 - 159,714,589 (-)NCBI
GRCh371159,682,079 - 159,684,396 (-)NCBI
Build 361157,948,703 - 157,951,003 (-)NCBI Archive
HuRef1131,038,539 - 131,040,831 (-)ENTREZGENE
CHM1_11161,076,594 - 161,078,894 (-)NCBI
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001329057   ⟹   NP_001315986
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381159,712,289 - 159,714,589 (-)NCBI
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001329058   ⟹   NP_001315987
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381159,712,289 - 159,714,589 (-)NCBI
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001382703   ⟹   NP_001369632
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381159,712,289 - 159,714,589 (-)NCBI
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBI
Sequence:
RefSeq Acc Id: NP_000558   ⟸   NM_000567
- Peptide Label: isoform 1 precursor
- UniProtKB: P02741 (UniProtKB/Swiss-Prot),   Q08AK3 (UniProtKB/Swiss-Prot),   D3DVE0 (UniProtKB/Swiss-Prot),   D3DVD9 (UniProtKB/Swiss-Prot),   A8K078 (UniProtKB/Swiss-Prot),   Q8WW75 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001315987   ⟸   NM_001329058
- Peptide Label: isoform 2 precursor
- UniProtKB: P02741 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001315986   ⟸   NM_001329057
- Peptide Label: isoform 1 precursor
- UniProtKB: P02741 (UniProtKB/Swiss-Prot),   Q08AK3 (UniProtKB/Swiss-Prot),   D3DVE0 (UniProtKB/Swiss-Prot),   D3DVD9 (UniProtKB/Swiss-Prot),   A8K078 (UniProtKB/Swiss-Prot),   Q8WW75 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001369632   ⟸   NM_001382703
- Peptide Label: isoform 3 precursor
- UniProtKB: Q5VVP7 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSP00000255030   ⟸   ENST00000255030
Ensembl Acc Id: ENSP00000357091   ⟸   ENST00000368110
Ensembl Acc Id: ENSP00000357093   ⟸   ENST00000368112
Ensembl Acc Id: ENSP00000357092   ⟸   ENST00000368111
Ensembl Acc Id: ENSP00000402788   ⟸   ENST00000437342
Protein Domains
Pentraxin (PTX)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P02741-F1-model_v2 AlphaFold P02741 1-224 view protein structure

Promoters
RGD ID:6849600
Promoter ID:EP26029
Type:single initiation site
Name:HS_CRP
Description:C-reactive protein.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Primer extension; Primer extension; transgenic organisms
Regulation:liver; (induced by or strongly expressed in) acute phase
Position:
Human AssemblyChrPosition (strand)Source
Build 361157,951,003 - 157,951,063EPD
RGD ID:6857722
Promoter ID:EPDNEW_H2026
Type:multiple initiation site
Name:CRP_1
Description:C-reactive protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381159,714,589 - 159,714,649EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:2367 AgrOrtholog
COSMIC CRP COSMIC
Ensembl Genes ENSG00000132693 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000255030 ENTREZGENE
  ENST00000255030.9 UniProtKB/Swiss-Prot
  ENST00000368110 ENTREZGENE
  ENST00000368110.1 UniProtKB/TrEMBL
  ENST00000368111.5 UniProtKB/TrEMBL
  ENST00000368112 ENTREZGENE
  ENST00000368112.5 UniProtKB/Swiss-Prot
  ENST00000437342.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000132693 GTEx
HGNC ID HGNC:2367 ENTREZGENE
Human Proteome Map CRP Human Proteome Map
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pentaxin_CS UniProtKB/Swiss-Prot
  Pentraxin-related UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pentraxin_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:1401 UniProtKB/Swiss-Prot
NCBI Gene 1401 ENTREZGENE
OMIM 123260 OMIM
PANTHER C-REACTIVE PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-REACTIVE PROTEIN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pentaxin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB CRP RGD, PharmGKB
PRINTS PENTAXIN UniProtKB/Swiss-Prot
PROSITE PTX_1 UniProtKB/Swiss-Prot
  PTX_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PTX UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K078 ENTREZGENE
  C9JRE9_HUMAN UniProtKB/TrEMBL
  CRP_HUMAN UniProtKB/Swiss-Prot
  D3DVD9 ENTREZGENE
  D3DVE0 ENTREZGENE
  P02741 ENTREZGENE
  Q08AK3 ENTREZGENE
  Q5VVP7 ENTREZGENE, UniProtKB/TrEMBL
  Q8WW75 ENTREZGENE
UniProt Secondary A8K078 UniProtKB/Swiss-Prot
  D3DVD9 UniProtKB/Swiss-Prot
  D3DVE0 UniProtKB/Swiss-Prot
  Q08AK3 UniProtKB/Swiss-Prot
  Q8WW75 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-23 CRP  C-reactive protein    C-reactive protein, pentraxin-related  Symbol and/or name change 5135510 APPROVED