LOC101969640 (C-reactive protein) - Rat Genome Database

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Gene: LOC101969640 (C-reactive protein) Ictidomys tridecemlineatus
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Symbol: LOC101969640
Name: C-reactive protein
RGD ID: 12713388
Description: ENCODES a protein that exhibits cholesterol binding (ortholog); identical protein binding (ortholog); low-density lipoprotein particle binding (ortholog); INVOLVED IN acute-phase response (ortholog); aging (ortholog); cellular response to calcium ion (ortholog); PARTICIPATES IN classical complement pathway; interleukin-6 signaling pathway; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Acute Coronary Syndrome (ortholog); acute kidney failure (ortholog); FOUND IN extracellular space (ortholog); filopodium (ortholog); growth cone (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Crp
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050585,866,551 - 5,870,192 (-)NCBI
SpeTri2.0NW_004936740885,855 - 888,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (ISO)
Acute Coronary Syndrome  (ISO)
acute kidney failure  (ISO)
acute stress disorder  (ISO)
Acute Uveitis  (ISO)
aggressive periodontitis  (ISO)
Albuminuria  (ISO)
Alcoholic Fatty Liver  (ISO)
alcoholic liver cirrhosis  (ISO)
Alzheimer's disease  (ISO)
ankylosing spondylitis  (ISO)
antiphospholipid syndrome  (ISO)
anxiety disorder  (ISO)
Arsenic Poisoning  (ISO)
aspergillosis  (ISO)
asthma  (ISO)
atherosclerosis  (ISO)
atrial fibrillation  (ISO)
Autoimmune Interstitial Lung, Joint, and Kidney Disease  (ISO)
Bacteremia  (ISO)
bacterial infectious disease  (ISO)
bacterial meningitis  (ISO)
Behcet's disease  (ISO)
Brain Injuries  (ISO)
breast cancer  (ISO)
breast carcinoma  (ISO)
bronchiolitis  (ISO)
Burns  (ISO)
Cardiac Arrhythmias  (ISO)
cardiovascular system disease  (ISO)
cerebrovascular disease  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chronic Hepatitis C  (ISO)
chronic obstructive pulmonary disease  (ISO)
colon cancer  (ISO)
congestive heart failure  (ISO)
Contrast-Induced Nephropathy  (ISO)
coronary artery disease  (ISO)
COVID-19  (ISO)
Crohn's disease  (ISO)
Diabetic Foot  (ISO)
Diabetic Nephropathies  (ISO)
diabetic retinopathy  (ISO)
disease by infectious agent  (ISO)
disease of metabolism  (ISO)
Drug Hypersensitivity Syndrome  (ISO)
end stage renal disease  (ISO)
Experimental Arthritis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
familial hyperlipidemia  (ISO)
Fever of Unknown Origin  (ISO)
gastrointestinal stromal tumor  (ISO)
heart disease  (ISO)
hepatocellular carcinoma  (ISO)
human immunodeficiency virus infectious disease  (ISO)
Human Influenza  (ISO)
hypertension  (ISO)
hypertensive retinopathy  (ISO)
Hypertriglyceridemia  (ISO)
Hypoxia  (ISO)
Hypoxia-Ischemia, Brain  (ISO)
Inflammation  (ISO)
inflammatory bowel disease  (ISO)
intermediate coronary syndrome  (ISO)
interstitial cystitis  (ISO)
interstitial nephritis  (ISO)
Intestinal Reperfusion Injury  (ISO)
iron deficiency anemia  (ISO)
juvenile rheumatoid arthritis  (ISO)
Kawasaki disease  (ISO)
kidney failure  (ISO)
Kuhnt-Junius degeneration  (ISO)
Left Ventricular Hypertrophy  (ISO)
leishmaniasis  (ISO)
liver cirrhosis  (ISO)
low tension glaucoma  (ISO)
Lung Neoplasms  (ISO)
lupus nephritis  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
malaria  (ISO)
mastoiditis  (ISO)
meningitis  (ISO)
mental depression  (ISO)
Metabolic Syndrome  (ISO)
mevalonic aciduria  (ISO)
middle cerebral artery infarction  (ISO)
mouth disease  (ISO)
Mycoplasma pneumoniae pneumonia  (ISO)
myocardial infarction  (ISO)
Myocardial Ischemia  (ISO)
Myocardial Reperfusion Injury  (ISO)
myocarditis  (ISO)
non-arteritic anterior ischemic optic neuropathy  (ISO)
obesity  (ISO)
obstructive sleep apnea  (ISO)
otitis externa  (ISO)
otitis media  (ISO)
Overactive Urinary Bladder  (ISO)
parathyroid carcinoma  (ISO)
Parkinson's disease  (ISO)
Pasteurellaceae Infections  (ISO)
pelvic inflammatory disease  (ISO)
periodontitis  (ISO)
pharyngoconjunctival fever  (ISO)
Pneumococcal Pneumonia  (ISO)
pneumonia  (ISO)
polymyalgia rheumatica  (ISO)
Polypoidal Choroidal Vasculopathy  (ISO)
Postoperative Atrial Fibrillation  (ISO)
Pseudomonas Infections  (ISO)
psoriasis  (ISO)
pulmonary hypertension  (ISO)
pulmonary sarcoidosis  (ISO)
pulmonary tuberculosis  (ISO)
pyelonephritis  (ISO)
renal cell carcinoma  (ISO)
Renal Colic  (ISO)
renal fibrosis  (ISO)
renal hypertension  (ISO)
retinal vein occlusion  (ISO)
rheumatoid arthritis  (ISO)
secondary hyperparathyroidism  (ISO)
Sepsis  (ISO)
Sjogren's syndrome  (ISO)
Spinal Cord Injuries  (ISO)
status epilepticus  (ISO)
Stevens-Johnson syndrome  (ISO)
systemic lupus erythematosus  (ISO)
temporal arteritis  (ISO)
thrombosis  (ISO)
Tubulointerstitial Nephritis and Uveitis  (ISO)
type 1 diabetes mellitus  (ISO)
type 2 diabetes mellitus  (ISO)
urticaria  (ISO)
uveal melanoma  (ISO)
vestibular neuronitis  (ISO)
visceral leishmaniasis  (ISO)
withdrawal disorder  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
LOC101969640
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050585,866,551 - 5,870,192 (-)NCBI
SpeTri2.0NW_004936740885,855 - 888,854 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381159,712,289 - 159,714,589 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1159,712,289 - 159,714,589 (-)EnsemblGRCh38hg38GRCh38
GRCh371159,682,079 - 159,684,379 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361157,948,703 - 157,951,003 (-)NCBINCBI36hg18NCBI36
Build 341156,495,152 - 156,497,452NCBI
Celera1132,750,525 - 132,752,817 (-)NCBI
Cytogenetic Map1q23.2NCBI
HuRef1131,038,539 - 131,040,831 (-)NCBIHuRef
CHM1_11161,076,594 - 161,078,894 (-)NCBICHM1_1
T2T-CHM13v2.01158,849,333 - 158,851,633 (-)NCBI
Crp
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391172,525,623 - 172,527,533 (+)NCBIGRCm39mm39
GRCm39 Ensembl1172,525,622 - 172,660,598 (+)Ensembl
GRCm381172,698,056 - 172,699,966 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1172,698,055 - 172,833,031 (+)EnsemblGRCm38mm10GRCm38
MGSCv371174,628,187 - 174,630,097 (+)NCBIGRCm37mm9NCBIm37
MGSCv361174,534,741 - 174,536,635 (+)NCBImm8
Celera1175,548,254 - 175,550,142 (+)NCBICelera
Cytogenetic Map1H3NCBI
cM Map180.13NCBI
Crp
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21385,131,635 - 85,175,179 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1385,124,977 - 85,175,178 (+)Ensembl
Rnor_6.01391,080,448 - 91,081,358 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1391,054,974 - 91,093,713 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01395,599,418 - 95,600,328 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41388,702,243 - 88,703,153 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11388,891,058 - 88,892,928 (+)NCBI
Celera1384,770,843 - 84,771,753 (+)NCBICelera
Cytogenetic Map13q24NCBI
CRP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11138,858,353 - 138,860,652 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01135,062,102 - 135,064,402 (-)NCBIMhudiblu_PPA_v0panPan3
CRP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13822,396,787 - 22,398,180 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3822,396,263 - 22,399,166 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3822,473,724 - 22,475,116 (+)NCBI
ROS_Cfam_1.03822,519,785 - 22,521,176 (+)NCBI
ROS_Cfam_1.0 Ensembl3822,519,714 - 22,522,146 (+)Ensembl
UMICH_Zoey_3.13822,286,369 - 22,287,757 (+)NCBI
UNSW_CanFamBas_1.03822,818,770 - 22,820,163 (+)NCBI
UU_Cfam_GSD_1.03823,230,160 - 23,231,548 (+)NCBI
CRP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl490,793,350 - 90,805,218 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1490,793,361 - 90,801,020 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2498,764,964 - 98,772,727 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103223751
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1204,232,262 - 4,235,826 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl204,232,913 - 4,235,377 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660383,340,251 - 3,342,511 (+)NCBIVero_WHO_p1.0
Crp
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247941,531,571 - 1,533,804 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247941,531,555 - 1,533,804 (+)NCBIHetGla_female_1.0hetGla2


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005339386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_005339386   ⟹   XP_005339443
RefSeq Status:
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_0244050585,866,551 - 5,870,192 (-)NCBI
SpeTri2.0NW_004936740885,855 - 888,854 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005339443 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3281031 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005339443   ⟸   XM_005339386
- UniProtKB: I3MS19 (UniProtKB/TrEMBL)
- Sequence:


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSTOG00000024783 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSSTOP00000014914 ENTREZGENE
  ENSSTOP00000014914.2 UniProtKB/TrEMBL
Ensembl Transcript ENSSTOT00000029422.2 UniProtKB/TrEMBL
InterPro ConA-like_dom_sf UniProtKB/TrEMBL
  Pentaxin_CS UniProtKB/TrEMBL
  Pentraxin-related UniProtKB/TrEMBL
NCBI Gene Crp ENTREZGENE
Pfam Pentaxin UniProtKB/TrEMBL
PRINTS PENTAXIN UniProtKB/TrEMBL
PROSITE PTX_1 UniProtKB/TrEMBL
  PTX_2 UniProtKB/TrEMBL
SMART PTX UniProtKB/TrEMBL
Superfamily-SCOP SSF49899 UniProtKB/TrEMBL
UniProt I3MS19 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-26 LOC101969640  C-reactive protein  Crp  C-reactive protein  Symbol and/or name change 5135510 APPROVED