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Gene: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Homo sapiens
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Symbol: KCNMA1
Name: potassium calcium-activated channel subfamily M alpha 1
Description: Exhibits actin binding activity; identical protein binding activity; and potassium channel activity. Involved in several processes, including cellular potassium ion homeostasis; negative regulation of cell volume; and smooth muscle contraction involved in micturition. Localizes to the apical plasma membrane; caveola; and voltage-gated potassium channel complex. Implicated in Alzheimer's disease and idiopathic generalized epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA205K10.1; big potassium channel alpha subunit; BK channel; BK channel alpha subunit; BKCA alpha subunit; BKTM; CADEDS; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; DKFZp686K1437; Drosophila slowpoke-like; hSlo; IEG16; k(VCA)alpha; KCa1.1; LIWAS; maxi K channel; maxi-K channel HSLO; MaxiK; MGC71881; mSLO1; PNKD3; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SAKCA; SLO; slo homolog; SLO-ALPHA; SLO1; slowpoke homolog; stretch-activated Kca channel
Orthologs:
Mus musculus (house mouse) : Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Kcnma1 (potassium calcium-activated channel subfamily M alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Kcnma1 (potassium calcium-activated channel subfamily M alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : KCNMA1 (potassium calcium-activated channel subfamily M alpha 1)
Canis lupus familiaris (dog) : KCNMA1 (potassium calcium-activated channel subfamily M alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Kcnma1 (potassium calcium-activated channel subfamily M alpha 1)
Sus scrofa (pig) : KCNMA1 (potassium calcium-activated channel subfamily M alpha 1)
Chlorocebus sabaeus (green monkey) : KCNMA1 (potassium calcium-activated channel subfamily M alpha 1)
Heterocephalus glaber (naked mole-rat) : Kcnma1 (potassium calcium-activated channel subfamily M alpha 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1076,869,601 - 77,638,369 (-)Ensembl
GRCh381076,869,601 - 77,637,969 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371078,629,359 - 79,397,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361078,299,366 - 79,067,583 (-)NCBINCBI36hg18NCBI36
Build 341078,314,640 - 79,067,583NCBI
Celera1071,914,113 - 72,684,182 (-)NCBI
Cytogenetic Map10q22.3NCBI
HuRef1072,624,294 - 73,391,824 (-)NCBIHuRef
CHM1_11078,911,952 - 79,680,009 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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