SMAD7 Human (+)-schisandrin B multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 mRNA] CTD PMID:31150632 SMAD7 Human (-)-ephedrine decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Ephedrine results in decreased expression of SMAD7 protein CTD PMID:32729338 SMAD7 Human (1->4)-beta-D-glucan multiple interactions ISO Smad7 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SMAD7 mRNA CTD PMID:36331819 SMAD7 Human 1,3-dinitrobenzene increases expression ISO Smad7 (Rattus norvegicus) 6480464 3-dinitrobenzene results in increased expression of SMAD7 mRNA CTD PMID:22841810 SMAD7 Human 17alpha-ethynylestradiol affects expression ISO Smad7 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of SMAD7 mRNA CTD PMID:17555576 SMAD7 Human 17beta-estradiol affects expression ISO Smad7 (Mus musculus) 6480464 Estradiol affects the expression of SMAD7 mRNA CTD PMID:15598610 SMAD7 Human 17beta-estradiol increases expression ISO Smad7 (Rattus norvegicus) 6480464 Estradiol results in increased expression of SMAD7 mRNA CTD PMID:32145629 SMAD7 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of SMAD7 mRNA CTD PMID:30165855 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Smad7 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of SMAD7 mRNA CTD PMID:24058054 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Smad7 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SMAD7 mRNA CTD PMID:33387578 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Smad7 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SMAD7 protein CTD PMID:33812962 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SMAD7 mRNA CTD PMID:20106945 and PMID:21632981 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Smad7 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of SMAD7 mRNA CTD PMID:22298810 and PMID:34747641 SMAD7 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Smad7 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of SMAD7 mRNA CTD PMID:19933214 SMAD7 Human 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Genistein inhibits the reaction [Galactosamine results in decreased expression of SMAD7 protein] CTD PMID:27876602 SMAD7 Human 2-amino-2-deoxy-D-galactopyranose decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Galactosamine results in decreased expression of SMAD7 protein CTD PMID:27876602 SMAD7 Human 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO Smad7 (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 SMAD7 Human 3,3',4,4',5-pentachlorobiphenyl increases expression EXP 6480464 3 more ... CTD PMID:35618242 SMAD7 Human 3-Methoxynobiletin affects phosphorylation EXP 6480464 3 more ... CTD PMID:29470423 SMAD7 Human 4,4'-diaminodiphenylmethane decreases expression ISO Smad7 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of SMAD7 mRNA CTD PMID:18648102 SMAD7 Human 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol S co-treated with Fulvestrant] results in decreased methylation of SMAD7 gene CTD PMID:31601247 SMAD7 Human 5-aza-2'-deoxycytidine multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Decitabine inhibits the reaction [TGFB1 protein results in decreased expression of SMAD7 mRNA] more ... CTD PMID:24211420 SMAD7 Human 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of SMAD7 mRNA CTD PMID:19194470 SMAD7 Human 6-propyl-2-thiouracil decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of SMAD7 mRNA CTD PMID:24780913 SMAD7 Human 7,9-dihydro-1H-purine-2,6,8(3H)-trione decreases expression EXP 6480464 Uric Acid results in decreased expression of SMAD7 mRNA CTD PMID:36850003 SMAD7 Human acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of SMAD7 mRNA CTD PMID:32763439 SMAD7 Human acteoside increases expression EXP 6480464 acteoside results in increased expression of SMAD7 protein CTD PMID:33522686 SMAD7 Human aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of SMAD7 gene and Aflatoxin B1 results in increased methylation of SMAD7 intron CTD PMID:28458013 and PMID:30157460 SMAD7 Human aflatoxin B1 increases expression ISO Smad7 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of SMAD7 mRNA CTD PMID:33354967 SMAD7 Human all-trans-retinoic acid increases expression ISO Smad7 (Mus musculus) 6480464 Tretinoin results in increased expression of SMAD7 protein CTD PMID:16410076 and PMID:33493612 SMAD7 Human all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of SMAD7 and Tretinoin results in increased expression of SMAD7 mRNA CTD PMID:21934132 more ... SMAD7 Human ammonium chloride affects expression ISO Smad7 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of SMAD7 mRNA CTD PMID:16483693 SMAD7 Human Ammothamnine increases expression ISO Smad7 (Mus musculus) 6480464 oxymatrine results in increased expression of SMAD7 mRNA CTD PMID:18395914 SMAD7 Human antigen multiple interactions ISO Smad7 (Mus musculus) 6480464 [Dronabinol inhibits the reaction [Antigens results in decreased expression of MIR29B-1 mRNA]] which results in increased expression of SMAD7 mRNA CTD PMID:27038180 SMAD7 Human aristolochic acid A decreases expression ISO Smad7 (Mus musculus) 6480464 aristolochic acid I results in decreased expression of SMAD7 mRNA and aristolochic acid I results in decreased expression of SMAD7 protein CTD PMID:26108275 SMAD7 Human arsane affects methylation EXP 6480464 Arsenic affects the methylation of SMAD7 gene CTD PMID:25304211 SMAD7 Human arsenic atom affects methylation EXP 6480464 Arsenic affects the methylation of SMAD7 gene CTD PMID:25304211 SMAD7 Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of SMAD7 mRNA CTD PMID:22378314 SMAD7 Human atrazine affects methylation ISO Smad7 (Rattus norvegicus) 6480464 Atrazine affects the methylation of SMAD7 gene CTD PMID:35440735 SMAD7 Human azoxystrobin multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 SMAD7 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of SMAD7 mRNA CTD PMID:26238291 SMAD7 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of SMAD7 3' UTR CTD PMID:27901495 SMAD7 Human benzo[e]pyrene increases methylation EXP 6480464 benzo(e)pyrene results in increased methylation of SMAD7 intron CTD PMID:30157460 SMAD7 Human beta-lapachone decreases expression EXP 6480464 beta-lapachone results in decreased expression of SMAD7 mRNA CTD PMID:38218311 SMAD7 Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of SMAD7 mRNA CTD PMID:38218311 SMAD7 Human bis(2-ethylhexyl) phthalate increases expression ISO Smad7 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of SMAD7 mRNA CTD PMID:35716406 SMAD7 Human bisphenol A affects expression ISO Smad7 (Rattus norvegicus) 6480464 bisphenol A affects the expression of SMAD7 mRNA CTD PMID:25181051 SMAD7 Human bisphenol A decreases expression ISO Smad7 (Mus musculus) 6480464 bisphenol A results in decreased expression of SMAD7 mRNA CTD PMID:35598803 SMAD7 Human bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of SMAD7 gene CTD PMID:31601247 SMAD7 Human bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SMAD7 gene CTD PMID:31601247 SMAD7 Human bisphenol A increases expression ISO Smad7 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of SMAD7 mRNA CTD PMID:34947998 SMAD7 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SMAD7 mRNA CTD PMID:29275510 SMAD7 Human bisphenol A affects methylation ISO Smad7 (Mus musculus) 6480464 bisphenol A affects the methylation of SMAD7 promoter CTD PMID:27334623 SMAD7 Human bleomycin A2 multiple interactions ISO Smad7 (Mus musculus) 6480464 S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] CTD PMID:29033951 SMAD7 Human bleomycin A2 decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Bleomycin results in decreased expression of SMAD7 mRNA CTD PMID:26093215 SMAD7 Human bleomycin A2 increases expression ISO Smad7 (Mus musculus) 6480464 Bleomycin results in increased expression of SMAD7 mRNA CTD PMID:29033951 SMAD7 Human cadmium atom multiple interactions ISO Smad7 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMAD7 mRNA CTD PMID:37325564 SMAD7 Human cadmium dichloride decreases expression EXP 6480464 Cadmium Chloride results in decreased expression of SMAD7 mRNA CTD PMID:38568856 SMAD7 Human cadmium dichloride multiple interactions ISO Smad7 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SMAD7 mRNA CTD PMID:37325564 SMAD7 Human cadmium sulfate multiple interactions ISO Smad7 (Mus musculus) 6480464 cadmium sulfate affects the reaction [MTF1 affects the expression of SMAD7 mRNA] CTD PMID:16221973 SMAD7 Human calcitriol increases expression EXP 6480464 Calcitriol results in increased expression of SMAD7 mRNA CTD PMID:16002434 and PMID:23589129 SMAD7 Human calcitriol multiple interactions EXP 6480464 FST protein inhibits the reaction [Calcitriol results in decreased expression of SMAD7 mRNA] CTD PMID:23589129 SMAD7 Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of SMAD7 mRNA CTD PMID:25979313 SMAD7 Human carbofuran decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Carbofuran results in decreased expression of SMAD7 mRNA and Carbofuran results in decreased expression of SMAD7 protein CTD PMID:28982980 SMAD7 Human carbon nanotube increases expression ISO Smad7 (Mus musculus) 6480464 Nanotubes and Carbon results in increased expression of SMAD7 mRNA CTD PMID:25554681 SMAD7 Human carbon nanotube decreases expression ISO Smad7 (Mus musculus) 6480464 Nanotubes and Carbon results in decreased expression of SMAD7 mRNA CTD PMID:25926378 SMAD7 Human carvedilol multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Carvedilol inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein] CTD PMID:30254303 SMAD7 Human chlordecone decreases expression ISO Smad7 (Mus musculus) 6480464 Chlordecone results in decreased expression of SMAD7 mRNA CTD PMID:33711761 SMAD7 Human chlorpyrifos multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 SMAD7 Human chlorpyrifos affects expression ISO Smad7 (Mus musculus) 6480464 Chlorpyrifos affects the expression of SMAD7 mRNA CTD PMID:37019170 SMAD7 Human choline multiple interactions ISO Smad7 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD7 gene more ... CTD PMID:20938992 and PMID:22915297 SMAD7 Human cisplatin decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of SMAD7 mRNA CTD PMID:22023808 SMAD7 Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of SMAD7 mRNA CTD PMID:27392435 SMAD7 Human cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of SMAD7 mRNA CTD PMID:27392435 SMAD7 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of SMAD7 mRNA CTD PMID:27594783 SMAD7 Human copper atom decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Copper results in decreased expression of SMAD7 mRNA CTD PMID:22465980 SMAD7 Human copper(0) decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Copper results in decreased expression of SMAD7 mRNA CTD PMID:22465980 SMAD7 Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of SMAD7 mRNA CTD PMID:19549813 SMAD7 Human crocidolite asbestos decreases expression EXP 6480464 Asbestos and Crocidolite results in decreased expression of SMAD7 mRNA CTD PMID:23634900 SMAD7 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of SMAD7 mRNA CTD PMID:27989131 SMAD7 Human dexamethasone decreases expression EXP 6480464 Dexamethasone results in decreased expression of SMAD7 mRNA CTD PMID:25047013 SMAD7 Human Dibutyl phosphate affects expression EXP 6480464 di-n-butylphosphoric acid affects the expression of SMAD7 mRNA CTD PMID:37042841 SMAD7 Human dibutyl phthalate decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of SMAD7 mRNA CTD PMID:21266533 SMAD7 Human dimethylarsinous acid decreases expression EXP 6480464 dimethylarsinous acid results in decreased expression of SMAD7 mRNA CTD PMID:16507463 SMAD7 Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of SMAD7 mRNA CTD PMID:26516004 SMAD7 Human diuron increases expression ISO Smad7 (Rattus norvegicus) 6480464 Diuron results in increased expression of SMAD7 mRNA CTD PMID:25152437 SMAD7 Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SMAD7 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of SMAD7 protein CTD PMID:18606404 SMAD7 Human enalapril increases expression ISO Smad7 (Rattus norvegicus) 6480464 Enalapril results in increased expression of SMAD7 mRNA and Enalapril results in increased expression of SMAD7 protein CTD PMID:19197123 and PMID:19349682 SMAD7 Human endosulfan decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of SMAD7 mRNA CTD PMID:29391264 SMAD7 Human endosulfan multiple interactions EXP 6480464 LY2109761 inhibits the reaction [Endosulfan results in decreased expression of SMAD7 protein] CTD PMID:34856488 SMAD7 Human endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of SMAD7 protein CTD PMID:34856488 and PMID:36513242 SMAD7 Human entinostat increases expression EXP 6480464 entinostat results in increased expression of SMAD7 mRNA CTD PMID:26272509 SMAD7 Human entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMAD7 mRNA CTD PMID:27188386 SMAD7 Human epoxiconazole decreases expression ISO Smad7 (Mus musculus) 6480464 epoxiconazole results in decreased expression of SMAD7 mRNA CTD PMID:35436446 SMAD7 Human ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of SMAD7 mRNA CTD PMID:23649840 SMAD7 Human flavonoids decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Flavonoids results in decreased expression of SMAD7 mRNA CTD PMID:18035473 SMAD7 Human flutamide increases expression ISO Smad7 (Rattus norvegicus) 6480464 Flutamide results in increased expression of SMAD7 mRNA and Flutamide results in increased expression of SMAD7 protein CTD PMID:16166221 SMAD7 Human folic acid multiple interactions ISO Smad7 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD7 gene CTD PMID:20938992 SMAD7 Human folic acid decreases expression ISO Smad7 (Mus musculus) 6480464 Folic Acid results in decreased expression of SMAD7 mRNA CTD PMID:25629700 SMAD7 Human formaldehyde decreases expression EXP 6480464 Formaldehyde results in decreased expression of SMAD7 mRNA CTD PMID:20655997 SMAD7 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of SMAD7 mRNA CTD PMID:23649840 SMAD7 Human fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of SMAD7 gene and [bisphenol S co-treated with Fulvestrant] results in decreased methylation of SMAD7 gene CTD PMID:31601247 SMAD7 Human galangin decreases expression EXP 6480464 galangin results in decreased expression of SMAD7 mRNA CTD PMID:25268046 SMAD7 Human genistein multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Genistein inhibits the reaction [Galactosamine results in decreased expression of SMAD7 protein] CTD PMID:27876602 SMAD7 Human gentamycin increases expression ISO Smad7 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of SMAD7 mRNA CTD PMID:33387578 SMAD7 Human geraniol increases expression EXP 6480464 geraniol results in increased expression of SMAD7 mRNA CTD PMID:27683099 SMAD7 Human glycyrrhizinic acid increases expression EXP 6480464 Glycyrrhizic Acid results in increased expression of SMAD7 protein CTD PMID:33522686 SMAD7 Human glyphosate multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 SMAD7 Human imidacloprid multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 SMAD7 Human indometacin increases expression EXP 6480464 Indomethacin results in increased expression of SMAD7 mRNA CTD PMID:16984733 SMAD7 Human inulin multiple interactions ISO Smad7 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SMAD7 mRNA CTD PMID:36331819 SMAD7 Human isobutyl nitrite increases expression ISO Smad7 (Mus musculus) 6480464 isobutyl nitrite results in increased expression of SMAD7 mRNA CTD PMID:16288974 SMAD7 Human L-methionine multiple interactions ISO Smad7 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of SMAD7 gene more ... CTD PMID:20938992 and PMID:22915297 SMAD7 Human lactucin increases expression ISO Smad7 (Mus musculus) 6480464 lactucin results in increased expression of SMAD7 protein CTD PMID:39164375 SMAD7 Human lactucin increases expression ISO Smad7 (Rattus norvegicus) 6480464 lactucin results in increased expression of SMAD7 protein CTD PMID:39164375 SMAD7 Human leflunomide increases expression EXP 6480464 leflunomide results in increased expression of SMAD7 mRNA CTD PMID:28988120 SMAD7 Human Licochalcone B increases expression EXP 6480464 licochalcone B results in increased expression of SMAD7 mRNA CTD PMID:33647349 SMAD7 Human manganese(II) chloride increases methylation EXP 6480464 manganese chloride results in increased methylation of SMAD7 gene CTD PMID:27913844 SMAD7 Human methapyrilene increases methylation EXP 6480464 Methapyrilene results in increased methylation of SMAD7 intron CTD PMID:30157460 SMAD7 Human methotrexate affects expression ISO Smad7 (Mus musculus) 6480464 Methotrexate affects the expression of SMAD7 mRNA CTD PMID:18502557 SMAD7 Human methoxychlor affects methylation ISO Smad7 (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of SMAD7 gene CTD PMID:35440735 SMAD7 Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of SMAD7 mRNA CTD PMID:23649840 SMAD7 Human methylseleninic acid increases expression EXP 6480464 methylselenic acid results in increased expression of SMAD7 mRNA CTD PMID:18548127 SMAD7 Human mono(2-ethylhexyl) phthalate affects expression ISO Smad7 (Mus musculus) 6480464 mono-(2-ethylhexyl)phthalate affects the expression of SMAD7 mRNA CTD PMID:21195148 SMAD7 Human Monobutylphthalate affects expression ISO Smad7 (Mus musculus) 6480464 monobutyl phthalate affects the expression of SMAD7 mRNA CTD PMID:21195148 SMAD7 Human N-methyl-4-phenylpyridinium decreases expression ISO Smad7 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of SMAD7 mRNA CTD PMID:28801915 SMAD7 Human N-methyl-N-nitrosourea decreases expression ISO Smad7 (Mus musculus) 6480464 Methylnitrosourea results in decreased expression of SMAD7 mRNA CTD PMID:25270620 SMAD7 Human N-nitrosodiethylamine increases expression ISO Smad7 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of SMAD7 protein CTD PMID:18971187 SMAD7 Human naphthalenes increases expression ISO Smad7 (Rattus norvegicus) 6480464 Naphthalenes results in increased expression of SMAD7 protein CTD PMID:17337753 SMAD7 Human nickel atom increases expression EXP 6480464 Nickel results in increased expression of SMAD7 mRNA CTD PMID:23195993 SMAD7 Human nicotinamide decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Niacinamide results in decreased expression of SMAD7 mRNA and Niacinamide results in decreased expression of SMAD7 protein CTD PMID:38555046 SMAD7 Human nitrofen decreases expression ISO Smad7 (Mus musculus) 6480464 nitrofen results in decreased expression of SMAD7 mRNA CTD PMID:12149686 SMAD7 Human octreotide decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Octreotide results in decreased expression of SMAD7 mRNA CTD PMID:23137853 SMAD7 Human ozone multiple interactions ISO Smad7 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of SMAD7 mRNA CTD PMID:34911549 SMAD7 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SMAD7 mRNA CTD PMID:22230336 SMAD7 Human paracetamol increases expression ISO Smad7 (Mus musculus) 6480464 Acetaminophen results in increased expression of SMAD7 mRNA CTD PMID:37179516 SMAD7 Human paracetamol decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Acetaminophen results in decreased expression of SMAD7 mRNA CTD PMID:33387578 SMAD7 Human paraquat increases secretion ISO Smad7 (Rattus norvegicus) 6480464 Paraquat results in increased secretion of SMAD7 protein CTD PMID:33000210 SMAD7 Human paraquat increases expression ISO Smad7 (Rattus norvegicus) 6480464 Paraquat results in increased expression of SMAD7 mRNA CTD PMID:33000210 SMAD7 Human paraquat multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 LY2109761 affects the reaction [Paraquat results in increased expression of and results in increased secretion of SMAD7 protein] more ... CTD PMID:33000210 SMAD7 Human pasireotide decreases expression ISO Smad7 (Rattus norvegicus) 6480464 pasireotide results in decreased expression of SMAD7 mRNA CTD PMID:23137853 SMAD7 Human perfluorohexanesulfonic acid decreases expression ISO Smad7 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in decreased expression of SMAD7 mRNA CTD PMID:37995155 SMAD7 Human perfluorooctane-1-sulfonic acid decreases expression ISO Smad7 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in decreased expression of SMAD7 mRNA CTD PMID:19162173 SMAD7 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Smad7 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of SMAD7 mRNA and [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of SMAD7 mRNA CTD PMID:36331819 SMAD7 Human perindopril increases expression ISO Smad7 (Rattus norvegicus) 6480464 Perindopril results in increased expression of SMAD7 protein CTD PMID:15619341 SMAD7 Human perindopril multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Perindopril inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein] CTD PMID:16872305 SMAD7 Human picrotoxin decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Picrotoxin results in decreased expression of SMAD7 mRNA CTD PMID:15170462 SMAD7 Human pirfenidone multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SMAD7 mRNA] CTD PMID:12445421 SMAD7 Human pirinixic acid decreases expression ISO Smad7 (Mus musculus) 6480464 pirinixic acid results in decreased expression of SMAD7 mRNA CTD PMID:20059764 SMAD7 Human pirinixic acid multiple interactions ISO Smad7 (Mus musculus) 6480464 PPARA protein promotes the reaction [pirinixic acid results in decreased expression of SMAD7 mRNA] CTD PMID:20059764 SMAD7 Human potassium chromate decreases expression EXP 6480464 potassium chromate(VI) results in decreased expression of SMAD7 mRNA CTD PMID:22714537 SMAD7 Human progesterone increases expression ISO Smad7 (Rattus norvegicus) 6480464 Progesterone results in increased expression of SMAD7 mRNA CTD PMID:20726854 SMAD7 Human propiconazole decreases expression ISO Smad7 (Mus musculus) 6480464 propiconazole results in decreased expression of SMAD7 mRNA CTD PMID:21278054 SMAD7 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of SMAD7 mRNA CTD PMID:21632981 SMAD7 Human quercetin multiple interactions ISO Smad7 (Mus musculus) 6480464 Quercetin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SMAD7 mRNA] CTD PMID:22915297 SMAD7 Human raloxifene affects expression EXP 6480464 Raloxifene Hydrochloride affects the expression of SMAD7 mRNA CTD PMID:14699072 SMAD7 Human rebaudioside A multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] CTD PMID:30883860 SMAD7 Human resorcinol decreases expression EXP 6480464 resorcinol results in decreased expression of SMAD7 mRNA CTD PMID:22623647 SMAD7 Human resveratrol increases expression EXP 6480464 Resveratrol results in increased expression of SMAD7 mRNA and Resveratrol results in increased expression of SMAD7 protein CTD PMID:18089832 more ... SMAD7 Human resveratrol increases expression ISO Smad7 (Rattus norvegicus) 6480464 Resveratrol results in increased expression of SMAD7 mRNA and Resveratrol results in increased expression of SMAD7 protein CTD PMID:38555046 SMAD7 Human SB 431542 decreases expression ISO Smad7 (Mus musculus) 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide results in decreased expression of SMAD7 mRNA CTD PMID:20852150 SMAD7 Human SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SMAD7 Human serpentine asbestos decreases expression ISO Smad7 (Mus musculus) 6480464 Asbestos and Serpentine results in decreased expression of SMAD7 mRNA CTD PMID:16251409 SMAD7 Human silicon dioxide multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [tanshinone inhibits the reaction [Silicon Dioxide results in decreased expression of SMAD7 protein]] and tanshinone inhibits the reaction [Silicon Dioxide results in decreased expression of SMAD7 protein] CTD PMID:32097614 SMAD7 Human silicon dioxide decreases expression EXP 6480464 Silicon Dioxide results in decreased expression of SMAD7 protein CTD PMID:32097614 SMAD7 Human silver atom increases expression EXP 6480464 Silver results in increased expression of SMAD7 mRNA CTD PMID:26014281 and PMID:28959546 SMAD7 Human silver atom decreases expression ISO Smad7 (Mus musculus) 6480464 Silver results in decreased expression of SMAD7 mRNA CTD PMID:27131904 SMAD7 Human silver(0) increases expression EXP 6480464 Silver results in increased expression of SMAD7 mRNA CTD PMID:26014281 and PMID:28959546 SMAD7 Human silver(0) decreases expression ISO Smad7 (Mus musculus) 6480464 Silver results in decreased expression of SMAD7 mRNA CTD PMID:27131904 SMAD7 Human sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of SMAD7 mRNA CTD PMID:16507463 SMAD7 Human sorafenib decreases expression ISO Smad7 (Mus musculus) 6480464 sorafenib results in decreased expression of SMAD7 mRNA CTD PMID:21360571 SMAD7 Human streptozocin affects expression ISO Smad7 (Rattus norvegicus) 6480464 Streptozocin affects the expression of SMAD7 mRNA and Streptozocin affects the expression of SMAD7 protein CTD PMID:17437042 SMAD7 Human streptozocin decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Streptozocin results in decreased expression of SMAD7 mRNA CTD PMID:32959695 SMAD7 Human succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of SMAD7 mRNA CTD PMID:26378955 SMAD7 Human sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of SMAD7 mRNA CTD PMID:31533062 SMAD7 Human tacrolimus hydrate multiple interactions EXP 6480464 Tacrolimus inhibits the reaction [FKBP1A protein promotes the reaction [SMURF1 protein binds to SMAD7 protein binds to ACVR1B protein]] and Tacrolimus inhibits the reaction [SMAD7 protein binds to SMURF1 protein] CTD PMID:16720724 SMAD7 Human tacrolimus hydrate multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Tacrolimus promotes the reaction [Paraquat results in increased expression of and results in increased secretion of SMAD7 protein] and Tacrolimus promotes the reaction [Paraquat results in increased expression of SMAD7 mRNA] CTD PMID:33000210 SMAD7 Human tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of SMAD7 mRNA CTD PMID:14699072 SMAD7 Human tamoxifen affects expression ISO Smad7 (Mus musculus) 6480464 Tamoxifen affects the expression of SMAD7 mRNA CTD PMID:17555576 SMAD7 Human Tanshinone I multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [tanshinone inhibits the reaction [Silicon Dioxide results in decreased expression of SMAD7 protein]] and tanshinone inhibits the reaction [Silicon Dioxide results in decreased expression of SMAD7 protein] CTD PMID:32097614 SMAD7 Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of SMAD7 mRNA CTD PMID:15336504 SMAD7 Human testosterone increases expression ISO Smad7 (Mus musculus) 6480464 Testosterone results in increased expression of SMAD7 mRNA CTD PMID:22138414 SMAD7 Human tetrachloromethane increases expression ISO Smad7 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of SMAD7 mRNA CTD PMID:12445421 SMAD7 Human tetrachloromethane decreases expression ISO Smad7 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of SMAD7 mRNA CTD PMID:25912033 SMAD7 Human tetrachloromethane increases expression ISO Smad7 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of SMAD7 mRNA CTD PMID:25827057 SMAD7 Human tetrachloromethane increases methylation ISO Smad7 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased methylation of SMAD7 promoter CTD PMID:24211420 SMAD7 Human tetrachloromethane decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of SMAD7 mRNA and Carbon Tetrachloride results in decreased expression of SMAD7 protein CTD PMID:16872305 more ... SMAD7 Human tetrachloromethane multiple interactions ISO Smad7 (Mus musculus) 6480464 SMAD7 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of CCN2 protein] CTD PMID:17657819 SMAD7 Human tetrachloromethane multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Carvedilol inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein] more ... CTD PMID:12445421 more ... SMAD7 Human thapsigargin decreases expression ISO Smad7 (Mus musculus) 6480464 Thapsigargin results in decreased expression of SMAD7 protein CTD PMID:24648495 SMAD7 Human thiabendazole multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with Glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of SMAD7 mRNA CTD PMID:33854195 SMAD7 Human thioacetamide decreases expression ISO Smad7 (Rattus norvegicus) 6480464 Thioacetamide results in decreased expression of SMAD7 protein CTD PMID:30883860 SMAD7 Human thioacetamide increases expression ISO Smad7 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of SMAD7 mRNA CTD PMID:34492290 and PMID:38504479 SMAD7 Human thioacetamide multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 rebaudioside A inhibits the reaction [Thioacetamide results in decreased expression of SMAD7 protein] more ... CTD PMID:30883860 and PMID:38504479 SMAD7 Human thiram increases expression EXP 6480464 Thiram results in increased expression of SMAD7 mRNA CTD PMID:38568856 SMAD7 Human thymoquinone multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 thymoquinone inhibits the reaction [Thioacetamide results in increased expression of SMAD7 mRNA] CTD PMID:38504479 SMAD7 Human titanium dioxide decreases expression ISO Smad7 (Mus musculus) 6480464 titanium dioxide results in decreased expression of SMAD7 mRNA CTD PMID:23557971 SMAD7 Human titanium dioxide increases methylation ISO Smad7 (Mus musculus) 6480464 titanium dioxide results in increased methylation of SMAD7 gene CTD PMID:35295148 SMAD7 Human titanium dioxide decreases methylation ISO Smad7 (Mus musculus) 6480464 titanium dioxide results in decreased methylation of SMAD7 promoter CTD PMID:35295148 SMAD7 Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of SMAD7 mRNA CTD PMID:24935251 and PMID:26272509 SMAD7 Human trichostatin A multiple interactions EXP 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMAD7 mRNA CTD PMID:27188386 SMAD7 Human triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of SMAD7 mRNA CTD PMID:37042841 SMAD7 Human triptonide increases expression ISO Smad7 (Mus musculus) 6480464 triptonide results in increased expression of SMAD7 mRNA CTD PMID:33045310 SMAD7 Human ursodeoxycholic acid increases expression ISO Smad7 (Rattus norvegicus) 6480464 Ursodeoxycholic Acid results in increased expression of SMAD7 mRNA and Ursodeoxycholic Acid results in increased expression of SMAD7 protein CTD PMID:19493473 SMAD7 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of SMAD7 mRNA CTD PMID:25979313 SMAD7 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of SMAD7 mRNA CTD PMID:24383497 more ... SMAD7 Human valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SMAD7 mRNA CTD PMID:27188386 SMAD7 Human valsartan increases expression ISO Smad7 (Rattus norvegicus) 6480464 Valsartan results in increased expression of SMAD7 protein CTD PMID:15619341 SMAD7 Human valsartan multiple interactions ISO Smad7 (Rattus norvegicus) 6480464 Valsartan inhibits the reaction [Carbon Tetrachloride results in decreased expression of SMAD7 protein] CTD PMID:16872305 SMAD7 Human vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of SMAD7 mRNA CTD PMID:27188386
