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Gene: RPS6KB1 (ribosomal protein S6 kinase B1) Homo sapiens
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Symbol: RPS6KB1
Name: ribosomal protein S6 kinase B1
Description: Exhibits protein serine/threonine/tyrosine kinase activity. Involved in several processes, including G1/S transition of mitotic cell cycle; TOR signaling; and negative regulation of insulin receptor signaling pathway. Localizes to the mitochondrion and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 70 kDa ribosomal protein S6 kinase 1; p70 ribosomal S6 kinase alpha; p70 S6 kinase alpha; p70 S6 kinase, alpha; p70 S6 kinase, alpha 1; p70 S6 kinase, alpha 2; p70 S6K-alpha; p70 S6KA; p70(S6K)-alpha; p70-alpha; p70-S6K; p70-S6K 1; P70S6K1; PS6K; ribosomal protein S6 kinase beta-1; ribosomal protein S6 kinase I; ribosomal protein S6 kinase, 70kDa, polypeptide 1; s6 kinase; S6K; S6K-beta-1; S6K1; serine/threonine kinase 14 alpha; serine/threonine-protein kinase 14A; STK14A
Orthologs:
Mus musculus (house mouse) : Rps6kb1 (ribosomal protein S6 kinase, polypeptide 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rps6kb1 (ribosomal protein S6 kinase B1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6kb1 (ribosomal protein S6 kinase B1)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KB1 (ribosomal protein S6 kinase B1)
Canis lupus familiaris (dog) : RPS6KB1 (ribosomal protein S6 kinase B1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6kb1 (ribosomal protein S6 kinase B1)
Sus scrofa (pig) : RPS6KB1 (ribosomal protein S6 kinase B1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381759,893,046 - 59,950,574 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371757,970,407 - 58,027,787 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361755,325,225 - 55,382,569 (+)NCBINCBI36hg18NCBI36
Build 341755,325,224 - 55,382,566NCBI
Celera1754,433,949 - 54,491,301 (+)NCBI
Cytogenetic Map17q23.1NCBI
HuRef1753,342,941 - 53,400,248 (+)NCBIHuRef
CHM1_11758,034,428 - 58,091,804 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RPS6KB1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731644
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.