ARRB2 (arrestin beta 2) - Rat Genome Database

Name: ARRB2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: ARRB2 (arrestin beta 2) Homo sapiens

Analyze

Symbol:

ARRB2

Name:

arrestin beta 2

RGD ID:

731570

HGNC Page

HGNC:712

Description:

Enables angiotensin receptor binding activity and ubiquitin protein ligase binding activity. Involved in several processes, including desensitization of G protein-coupled receptor signaling pathway; negative regulation of NF-kappaB transcription factor activity; and positive regulation of ERK1 and ERK2 cascade. Located in several cellular components, including cytosol; endocytic vesicle; and nucleoplasm. Biomarker of portal hypertension.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

ARB2; ARR2; arrestin 3; arrestin beta-2; arrestin, beta 2; BARR2; beta-arrestin-2; DKFZp686L0365; non-visual arrestin-3

RGD Orthologs

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Arrb2 (arrestin, beta 2)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Arrb2 (arrestin, beta 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Chinchilla lanigera (long-tailed chinchilla):	Arrb2 (arrestin beta 2)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	ARRB2 (arrestin beta 2)	NCBI	Ortholog
Canis lupus familiaris (dog):	ARRB2 (arrestin beta 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Arrb2 (arrestin beta 2)	NCBI	Ortholog
Sus scrofa (pig):	ARRB2 (arrestin beta 2)	HGNC	EggNOG, Ensembl, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Chlorocebus sabaeus (green monkey):	ARRB2 (arrestin beta 2)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Arrb2 (arrestin beta 2)	NCBI	Ortholog
Other homologs ²
Mus musculus (house mouse):	Arrb1 (arrestin, beta 1)	HGNC	OrthoDB, OrthoMCL
Rattus norvegicus (Norway rat):	Arrb1 (arrestin, beta 1)	HGNC	OrthoDB
Sus scrofa (pig):	ARRB1 (arrestin beta 1)	HGNC	OrthoDB
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Arrb2 (arrestin, beta 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Arrb2 (arrestin, beta 2)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	arrb2b (arrestin, beta 2b)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Danio rerio (zebrafish):	arrb2a (arrestin, beta 2a)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Caenorhabditis elegans (roundworm):	arr-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	krz	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	17	4,710,596 - 4,721,499 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	4,613,927 - 4,624,792 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	4,560,538 - 4,571,544 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	4,560,537 - 4,571,543	NCBI
Celera	17	4,629,166 - 4,639,975 (+)	NCBI		Celera
Cytogenetic Map	17	p13.2	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI		HuRef
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI		T2T-CHM13v2.0

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (EXP)

Arteriovenous Fistula (ISO)

Experimental Arthritis (ISO)

Experimental Liver Cirrhosis (EXP)

Experimental Liver Neoplasms (ISO)

genetic disease (IAGP)

hepatocellular carcinoma (ISO)

hypertension (ISO)

Myocardial Reperfusion Injury (ISO)

portal hypertension (IEP,ISO)

renal fibrosis (ISO)

Transplant Rejection (ISO)

type 2 diabetes mellitus (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin (EXP,ISO)

1,1-dichloroethene (ISO)

1,2-dichloroethane (ISO)

1-naphthyl isothiocyanate (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2-arachidonoylglycerol (EXP)

3',5'-cyclic AMP (EXP)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

acetamide (ISO)

acrolein (EXP)

Aflatoxin B2 alpha (EXP)

all-trans-retinoic acid (EXP)

alpha-pinene (EXP)

alprenolol (EXP)

ammonium chloride (ISO)

anandamide (EXP)

antirheumatic drug (EXP)

ATP (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[e]pyrene (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

calcium atom (ISO)

calcium(0) (ISO)

cannabidiol (ISO)

carbon nanotube (ISO)

carvedilol (EXP,ISO)

celastrol (EXP)

CGP 52608 (EXP)

chrysin (ISO)

cisplatin (EXP)

copper atom (EXP)

copper(0) (EXP)

corticosterone (ISO)

dextran sulfate (ISO)

dibutyl phthalate (ISO)

dichlorine (ISO)

dobutamine (EXP)

dopamine (EXP)

Endomorphin-2 (ISO)

enzyme inhibitor (EXP)

ethanol (ISO)

fentanyl (EXP,ISO)

fenthion (ISO)

flavonoids (ISO)

fluoxetine (ISO)

gentamycin (ISO)

hydromorphone (ISO)

ICI 118551 (EXP)

isoprenaline (EXP,ISO)

ivermectin (EXP)

leukotriene D4 (EXP)

methamphetamine (EXP)

methapyrilene (EXP)

methidathion (ISO)

methoxyacetic acid (ISO)

methylmercury chloride (ISO)

metoprolol (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Monobutylphthalate (ISO)

morphine (EXP,ISO)

N-nitrosodiethylamine (ISO)

N-nitrosodimethylamine (ISO)

nickel atom (EXP)

nickel dichloride (EXP)

ozone (EXP,ISO)

pamoic acid (EXP)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

propranolol (EXP)

resveratrol (EXP)

rimonabant (EXP)

S-nitroso-L-cysteine (EXP)

silicon dioxide (ISO)

sodium chloride (EXP)

superoxide (ISO)

T-2 toxin (EXP)

testosterone (EXP)

tetrachloromethane (ISO)

thioacetamide (ISO)

titanium dioxide (ISO)

trichloroethene (ISO)

triptonide (ISO)

tungsten (ISO)

valproic acid (EXP)

vancomycin (ISO)

WIN 55212-2 (EXP)

zinc atom (EXP)

zinc dichloride (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adult walking behavior (IEA)

brain development (IEA)

brain development (IEA,ISO)

cell chemotaxis (IMP)

desensitization of G protein-coupled receptor signaling pathway by arrestin (IEA,IMP,ISO)

detection of temperature stimulus involved in sensory perception of pain (IEA,ISO)

dopamine receptor signaling pathway (NAS)

endocytosis (IEA,ISO)

excitatory postsynaptic potential (NAS)

follicle-stimulating hormone signaling pathway (IEA,ISO)

G protein-coupled receptor internalization (IBA,IDA,IMP,TAS)

G protein-coupled receptor signaling pathway (IEA,ISO)

modulation of chemical synaptic transmission (IEA)

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process (IEA,ISO)

negative regulation of GTPase activity (IEA,ISO)

negative regulation of I-kappaB kinase/NF-kappaB signaling (IDA)

negative regulation of interleukin-1 beta production (IEA)

negative regulation of interleukin-12 production (IEA)

negative regulation of interleukin-6 production (IEA)

negative regulation of natural killer cell mediated cytotoxicity (IMP)

negative regulation of neuron apoptotic process (IEA,ISO)

negative regulation of NF-kappaB transcription factor activity (IDA)

negative regulation of protein kinase B signaling (NAS)

negative regulation of protein phosphorylation (IEA)

negative regulation of protein ubiquitination (IDA,IEA,ISO)

negative regulation of release of cytochrome c from mitochondria (IEA,ISO)

negative regulation of signal transduction (IEA)

negative regulation of smooth muscle cell apoptotic process (IEA,ISO)

negative regulation of toll-like receptor signaling pathway (IEA)

negative regulation of tumor necrosis factor production (IEA)

positive regulation of calcium ion transport (IEA,ISO)

positive regulation of cardiac muscle cell differentiation (IEA)

positive regulation of collagen biosynthetic process (IEA,ISO)

positive regulation of DNA biosynthetic process (IEA,ISO)

positive regulation of epithelial cell apoptotic process (IEA,ISO)

positive regulation of ERK1 and ERK2 cascade (IBA,IDA,IEA,IMP,ISO)

positive regulation of gene expression (IEA)

positive regulation of peptidyl-serine phosphorylation (IEA,ISO)

positive regulation of peptidyl-tyrosine phosphorylation (IEA,ISO)

positive regulation of protein kinase B signaling (IEA,ISO)

positive regulation of protein phosphorylation (IEA,ISO)

positive regulation of receptor internalization (IEA,IMP,ISO)

positive regulation of synaptic transmission, dopaminergic (IEA)

postsynaptic signal transduction (IEA)

proteasome-mediated ubiquitin-dependent protein catabolic process (IMP)

protein transport (IEA)

protein ubiquitination (IMP)

receptor internalization (IDA)

regulation of G protein-coupled receptor signaling pathway (IEA,ISO)

regulation of protein phosphorylation (IEA,ISO)

signal transduction (IEA)

transcription by RNA polymerase II (IDA)

transforming growth factor beta receptor signaling pathway (IDA)

Cellular Component

basolateral plasma membrane (IEA,ISO)

clathrin-coated pit (IEA)

cytoplasm (IBA)

cytoplasm (IC)

cytoplasm (IDA)

cytoplasm (IDA,IEA)

cytoplasm (ISO)

cytoplasmic vesicle (IDA)

cytoplasmic vesicle (IEA)

cytosol (IDA)

cytosol (IDA,TAS)

cytosol (TAS)

dendritic spine (IEA,ISO)

endocytic vesicle (IDA)

endosome (IEA,ISO)

glutamatergic synapse (IEA,ISO)

membrane (IEA)

nucleoplasm (IDA)

nucleus (IDA)

nucleus (IEA)

plasma membrane (IDA)

plasma membrane (IEA)

plasma membrane (TAS)

postsynaptic density (IEA)

postsynaptic density (ISO)

postsynaptic membrane (IEA,ISO)

Molecular Function

14-3-3 protein binding (IEA,ISO)

alpha-1A adrenergic receptor binding (IEA,ISO)

alpha-1B adrenergic receptor binding (IEA,ISO)

angiotensin receptor binding (IBA,IPI)

arrestin family protein binding (IEA)

D1 dopamine receptor binding (IEA,ISO)

enzyme binding (IPI)

follicle-stimulating hormone receptor binding (IEA,ISO)

G protein-coupled receptor binding (IBA,IPI)

identical protein binding (IEA)

mitogen-activated protein kinase binding (IEA,ISO)

molecular adaptor activity (IDA)

platelet activating factor receptor binding (IEA,ISO)

protein binding (IPI,ISO)

protein domain specific binding (IEA,ISO)

protein kinase B binding (IEA)

protein-containing complex binding (IEA,ISO)

signaling receptor binding (IPI)

type 1 angiotensin receptor binding (IEA,ISO)

type 2A serotonin receptor binding (IEA,ISO)

ubiquitin protein ligase binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

angiotensin II signaling pathway via AT1 receptor (TAS)

calcium signaling pathway via the calcium-sensing receptor (IDA,ISO)

corticotropin-releasing hormone signaling pathway (TAS)

dopamine signaling pathway via D1 family of receptors (TAS)

dopamine signaling pathway via D2 family of receptors (TAS)

eicosanoid signaling pathway (EXP)

endocytosis pathway (IEA)

epinephrine signaling pathway via adrenergic receptor beta (TAS)

Hedgehog signaling pathway (EXP)

kinin signaling pathway (IDA)

mitogen activated protein kinase signaling pathway (IEA)

nuclear factor kappa B signaling pathway (EXP)

parathyroid hormone signaling pathway (TAS)

transforming growth factor-beta Smad dependent signaling pathway (EXP)

visual phototransduction pathway (IEA)

Wnt signaling, non-canonical pathway (EXP)

References

References - curated

#	Reference Title	Reference Citation
1.	Beta-arrestins: multifunctional cellular mediators.	Barki-Harrington L and Rockman HA, Physiology (Bethesda). 2008 Feb;23:17-22.
2.	The physiology, signaling, and pharmacology of dopamine receptors.	Beaulieu JM and Gainetdinov RR, Pharmacol Rev. 2011 Mar;63(1):182-217. doi: 10.1124/pr.110.002642. Epub 2011 Feb 8.
3.	Reactive oxygen species are involved in regulating hypocontractility of mesenteric artery to norepinephrine in cirrhotic rats with portal hypertension.	Chen W, etal., Int J Biol Sci. 2014 Mar 15;10(4):386-95. doi: 10.7150/ijbs.8081. eCollection 2014.
4.	Gender related alterations of beta-adrenoceptor mechanisms in heart failure due to arteriovenous fistula.	Dent MR, etal., J Cell Physiol. 2011 Oct 20. doi: 10.1002/jcp.23058.
5.	GRK mythology: G-protein receptor kinases in cardiovascular disease.	Dorn GW 2nd J Mol Med (Berl). 2009 May;87(5):455-63. Epub 2009 Feb 20.
6.	Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice.	Fong AM, etal., Proc Natl Acad Sci U S A 2002 May 28;99(11):7478-83.
7.	GOAs Human GO annotations	GOA_HUMAN data from the GO Consortium
8.	Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets.	Hauger RL, etal., CNS Neurol Disord Drug Targets. 2006 Aug;5(4):453-79.
9.	Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats.	Khan MS, etal., Toxicol Appl Pharmacol. 2011 Feb 15;251(1):85-94. Epub 2010 Dec 15.
10.	Effects of Chinese Fructus Mume formula and its separated prescription extract on insulin resistance in type 2 diabetic rats.	Li JB, etal., J Huazhong Univ Sci Technolog Med Sci. 2013 Dec;33(6):877-85. doi: 10.1007/s11596-013-1215-7. Epub 2013 Dec 13.
11.	Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization.	Pi M, etal., Mol Endocrinol. 2005 Apr;19(4):1078-87. Epub 2005 Jan 6.
12.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
13.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
14.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
16.	Licochalcone B Ameliorates Liver Cancer via Targeting of Apoptotic Genes, DNA Repair Systems, and Cell Cycle Control.	Sadek K, etal., Iran J Pharm Res. 2020 Fall;19(4):372-386. doi: 10.22037/ijpr.2020.1101292.
17.	Angiotensin II-stimulated signaling through G proteins and beta-arrestin.	Shenoy SK and Lefkowitz RJ, Sci STKE. 2005 Nov 22;2005(311):cm14.
18.	Biased agonism of the calcium-sensing receptor.	Thomsen AR, etal., Cell Calcium. 2012 Feb;51(2):107-16. doi: 10.1016/j.ceca.2011.11.009. Epub 2011 Dec 20.
19.	Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm.	Vilardaga JP, etal., Cell Mol Life Sci. 2011 Jan;68(1):1-13. doi: 10.1007/s00018-010-0465-9. Epub 2010 Aug 12.
20.	The expression change of beta-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony.	Wang QT, etal., J Ethnopharmacol. 2011 Jan 27;133(2):511-6. Epub 2010 Oct 19.
21.	Overactivation of cannabinoid receptor type 1 in rostral ventrolateral medulla promotes cardiovascular responses in spontaneously hypertensive rats.	Wang T, etal., J Hypertens. 2017 Mar;35(3):538-545. doi: 10.1097/HJH.0000000000001179.
22.	ß-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis.	Wang Y, etal., Am J Physiol Renal Physiol. 2017 Jul 1;313(1):F1-F8. doi: 10.1152/ajprenal.00588.2016. Epub 2017 Mar 8.
23.	ß-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signalling.	Wang Y, etal., Cardiovasc Res. 2017 Nov 1;113(13):1615-1626. doi: 10.1093/cvr/cvx147.
24.	Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys.	Zakrzewicz A, etal., Immunobiology. 2011 Jul;216(7):854-61. doi: 10.1016/j.imbio.2010.11.005. Epub 2010 Dec 3.
25.	Role of ssarrestins in bradykinin B2 receptor-mediated signalling.	Zimmerman B, etal., Cell Signal. 2011 Apr;23(4):648-59. doi: 10.1016/j.cellsig.2010.11.016. Epub 2010 Dec 8.

Additional References at PubMed

PMID:1517224	PMID:1587386	PMID:7695743	PMID:8486659	PMID:9037196	PMID:9169477	PMID:9346876	PMID:9668034	PMID:9852134	PMID:10097102	PMID:10644702	PMID:10858453
PMID:11090355	PMID:11226259	PMID:11259507	PMID:11279203	PMID:11356842	PMID:11418617	PMID:11533043	PMID:11535606	PMID:11588219	PMID:11723231	PMID:11729201	PMID:11867621
PMID:11877451	PMID:12070169	PMID:12105416	PMID:12186555	PMID:12370187	PMID:12393857	PMID:12464600	PMID:12473660	PMID:12477932	PMID:12488444	PMID:12538596	PMID:12582207
PMID:12654503	PMID:12949261	PMID:12958364	PMID:12958365	PMID:14500724	PMID:14602721	PMID:14702039	PMID:14711824	PMID:14769794	PMID:15125834	PMID:15173580	PMID:15231748
PMID:15355986	PMID:15361545	PMID:15364949	PMID:15489220	PMID:15489334	PMID:15528268	PMID:15611106	PMID:15618519	PMID:15626751	PMID:15634674	PMID:15635042	PMID:15687500
PMID:15699045	PMID:15699339	PMID:15728711	PMID:15817468	PMID:15878855	PMID:15888437	PMID:16038799	PMID:16051150	PMID:16103897	PMID:16169070	PMID:16181421	PMID:16308565
PMID:16325578	PMID:16378096	PMID:16412099	PMID:16513835	PMID:16524428	PMID:16580177	PMID:16605244	PMID:16611986	PMID:16689683	PMID:16820410	PMID:16894395	PMID:16956790
PMID:16968782	PMID:17005854	PMID:17038311	PMID:17148612	PMID:17233643	PMID:17256744	PMID:17272726	PMID:17353931	PMID:17377064	PMID:17500066	PMID:17540773	PMID:17565992
PMID:17579607	PMID:17620599	PMID:17713785	PMID:17761157	PMID:17846866	PMID:17855543	PMID:17947233	PMID:17978999	PMID:17984062	PMID:18006496	PMID:18036556	PMID:18039931
PMID:18191226	PMID:18408005	PMID:18435604	PMID:18445652	PMID:18544533	PMID:18604210	PMID:18621717	PMID:18691971	PMID:18703513	PMID:18768750	PMID:18787115	PMID:18801735
PMID:18802075	PMID:18937294	PMID:18940181	PMID:19008961	PMID:19049562	PMID:19060904	PMID:19071087	PMID:19122674	PMID:19165858	PMID:19171933	PMID:19188335	PMID:19202075
PMID:19219857	PMID:19239323	PMID:19262695	PMID:19279230	PMID:19306926	PMID:19363159	PMID:19416857	PMID:19424180	PMID:19453261	PMID:19458261	PMID:19531493	PMID:19730683
PMID:19782076	PMID:19794961	PMID:19846537	PMID:19874574	PMID:19955404	PMID:20035620	PMID:20056609	PMID:20100572	PMID:20228252	PMID:20360068	PMID:20457218	PMID:20478633
PMID:20497256	PMID:20505072	PMID:20514076	PMID:20656684	PMID:20664520	PMID:20734064	PMID:20801186	PMID:20802461	PMID:20864483	PMID:20936779	PMID:21081496	PMID:21112970
PMID:21118812	PMID:21149639	PMID:21152433	PMID:21256133	PMID:21258807	PMID:21296876	PMID:21306178	PMID:21318602	PMID:21321125	PMID:21378163	PMID:21389118	PMID:21466165
PMID:21502318	PMID:21589858	PMID:21642958	PMID:21644508	PMID:21645452	PMID:21708946	PMID:21711983	PMID:21833475	PMID:21873635	PMID:21952200	PMID:21988832	PMID:22006018
PMID:22190034	PMID:22242112	PMID:22282525	PMID:22300987	PMID:22333895	PMID:22369787	PMID:22457824	PMID:22472784	PMID:22523395	PMID:22562249	PMID:22610101	PMID:22735336
PMID:22773819	PMID:22871966	PMID:23011268	PMID:23069267	PMID:23077507	PMID:23139825	PMID:23188799	PMID:23208550	PMID:23236378	PMID:23242524	PMID:23266473	PMID:23290307
PMID:23297229	PMID:23302795	PMID:23341447	PMID:23382074	PMID:23449980	PMID:23527545	PMID:23541635	PMID:23782696	PMID:23809162	PMID:23818521	PMID:23820308	PMID:23826079
PMID:23985900	PMID:24056371	PMID:24069330	PMID:24157794	PMID:24169548	PMID:24265322	PMID:24377933	PMID:24386388	PMID:24561123	PMID:24568448	PMID:24635845	PMID:24658140
PMID:24733850	PMID:24817116	PMID:24817122	PMID:24867953	PMID:24898255	PMID:25038452	PMID:25134464	PMID:25162404	PMID:25170081	PMID:25241761	PMID:25281560	PMID:25354317
PMID:25402006	PMID:25416956	PMID:25425640	PMID:25450229	PMID:25752515	PMID:25766502	PMID:25973019	PMID:26077142	PMID:26157145	PMID:26186194	PMID:26211463	PMID:26211551
PMID:26257302	PMID:26324936	PMID:26344197	PMID:26371162	PMID:26372541	PMID:26399832	PMID:26449263	PMID:26467309	PMID:26496610	PMID:26545496	PMID:26638075	PMID:26673895
PMID:26829388	PMID:26839314	PMID:26850854	PMID:26852662	PMID:26885983	PMID:26898829	PMID:26927499	PMID:26957205	PMID:27007855	PMID:27155323	PMID:27188791	PMID:27226565
PMID:27468652	PMID:27502035	PMID:27523794	PMID:27561318	PMID:27657826	PMID:27818291	PMID:27835898	PMID:27895162	PMID:28062183	PMID:28140695	PMID:28169830	PMID:28298427
PMID:28300069	PMID:28325822	PMID:28427767	PMID:28472170	PMID:28485809	PMID:28514442	PMID:28515276	PMID:28581517	PMID:28611215	PMID:28652403	PMID:28733084	PMID:28947386
PMID:29031912	PMID:29054428	PMID:29330504	PMID:29377493	PMID:29467282	PMID:29515120	PMID:29620228	PMID:29658513	PMID:29734363	PMID:29999490	PMID:30196744	PMID:30354204
PMID:30355935	PMID:30462309	PMID:30504423	PMID:30554943	PMID:30787175	PMID:31091453	PMID:31106661	PMID:31239290	PMID:31344440	PMID:31515488	PMID:31776446	PMID:32027601
PMID:32132133	PMID:32296183	PMID:32450252	PMID:32505358	PMID:32513696	PMID:32601232	PMID:32707033	PMID:32780723	PMID:32819604	PMID:32828283	PMID:32860951	PMID:32877691
PMID:32962859	PMID:33042017	PMID:33158816	PMID:33187986	PMID:33204724	PMID:33288675	PMID:33367479	PMID:33649538	PMID:33710266	PMID:33741415	PMID:33783060	PMID:33811988
PMID:33871024	PMID:33961781	PMID:34001657	PMID:34007068	PMID:34031190	PMID:34450275	PMID:34484125	PMID:34507982	PMID:34710848	PMID:34887409	PMID:35189719	PMID:35256949
PMID:35788718	PMID:36095012	PMID:36215168	PMID:36284990	PMID:36744494	PMID:36853120

Genomics

Comparative Map Data

ARRB2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	17	4,710,596 - 4,721,499 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	4,613,927 - 4,624,792 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	4,560,538 - 4,571,544 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	4,560,537 - 4,571,543	NCBI
Celera	17	4,629,166 - 4,639,975 (+)	NCBI		Celera
Cytogenetic Map	17	p13.2	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI		HuRef
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI		T2T-CHM13v2.0

Arrb2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	70,323,051 - 70,331,654 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	70,323,461 - 70,331,654 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	70,432,485 - 70,440,828 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	70,432,635 - 70,440,828 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	70,246,155 - 70,254,176 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	70,248,893 - 70,257,018 (+)	NCBI		MGSCv36	mm8
Celera	11	77,978,619 - 77,986,640 (+)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.99	NCBI

Arrb2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	55,146,887 - 55,154,854 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	55,146,818 - 55,154,850 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	59,825,196 - 59,833,080 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	10	59,313,709 - 59,321,593 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	10	54,812,911 - 54,820,795 (+)	NCBI	Rnor_WKY
Rnor_6.0	10	57,040,252 - 57,048,045 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	57,040,267 - 57,048,134 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	56,797,489 - 56,805,282 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	57,244,071 - 57,284,166 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	57,289,995 - 57,297,789 (+)	NCBI
Celera	10	54,285,120 - 54,301,063 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

Arrb2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	10,110,003 - 10,123,022 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	10,109,985 - 10,118,687 (+)	NCBI	ChiLan1.0	ChiLan1.0

ARRB2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	17	4,757,048 - 4,767,517 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	4,757,048 - 4,767,517 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	17	4,766,616 - 4,777,253 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

ARRB2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	31,831,208 - 31,838,875 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	31,829,864 - 31,839,454 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	31,968,270 - 31,977,918 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	31,934,052 - 31,943,706 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	31,934,872 - 31,943,667 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	31,900,361 - 31,910,009 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	31,860,046 - 31,869,691 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	32,036,284 - 32,045,935 (-)	NCBI		UU_Cfam_GSD_1.0

Arrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	52,719,545 - 52,727,921 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936677	3,172,925 - 3,181,520 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936677	3,173,054 - 3,181,475 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ARRB2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	52,161,778 - 52,170,342 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	52,161,776 - 52,170,362 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	54,280,938 - 54,286,249 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ARRB2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	4,191,040 - 4,202,382 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	4,191,172 - 4,202,385 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	17,439,881 - 17,451,765 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Arrb2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	8,568,198 - 8,577,914 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	8,568,102 - 8,576,445 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in ARRB2
7 total Variants

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 17p13.3-13.2(chr17:193307-5652222)x1	copy number loss	See cases [RCV000053384]	Chr17:193307..5652222 [GRCh38] Chr17:45835..5555542 [GRCh37] Chr17:43098..5496266 [NCBI36] Chr17:17p13.3-13.2	pathogenic
GRCh38/hg38 17p13.2-13.1(chr17:3601515-7178024)x1	copy number loss	See cases [RCV000053406]	Chr17:3601515..7178024 [GRCh38] Chr17:3504809..7081343 [GRCh37] Chr17:3451558..7022067 [NCBI36] Chr17:17p13.2-13.1	pathogenic
GRCh38/hg38 17p13.2(chr17:4141725-4841701)x3	copy number gain	Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054003]\|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054003]\|See cases [RCV000054003]	Chr17:4141725..4841701 [GRCh38] Chr17:4045019..4744996 [GRCh37] Chr17:3991768..4691654 [NCBI36] Chr17:17p13.2	uncertain significance
NM_004313.3(ARRB2):c.541C>T (p.Pro181Ser)	single nucleotide variant	Malignant melanoma [RCV000071558]	Chr17:4717943 [GRCh38] Chr17:4621238 [GRCh37] Chr17:4567987 [NCBI36] Chr17:17p13.2	not provided
NM_004313.3(ARRB2):c.542C>T (p.Pro181Leu)	single nucleotide variant	Malignant melanoma [RCV000071559]	Chr17:4717944 [GRCh38] Chr17:4621239 [GRCh37] Chr17:4567988 [NCBI36] Chr17:17p13.2	not provided
GRCh38/hg38 17p13.3-13.2(chr17:2062380-5258340)x1	copy number loss	See cases [RCV000133721]	Chr17:2062380..5258340 [GRCh38] Chr17:1965674..5161635 [GRCh37] Chr17:1912424..5102359 [NCBI36] Chr17:17p13.3-13.2	pathogenic
GRCh38/hg38 17p13.3-13.1(chr17:162088-6959050)x1	copy number loss	See cases [RCV000134135]	Chr17:162088..6959050 [GRCh38] Chr17:45835..6862369 [GRCh37] Chr17:11879..6803093 [NCBI36] Chr17:17p13.3-13.1	pathogenic
GRCh38/hg38 17p13.3-13.1(chr17:198748-7491129)x3	copy number gain	See cases [RCV000134970]	Chr17:198748..7491129 [GRCh38] Chr17:50690..7394448 [GRCh37] Chr17:48539..7335172 [NCBI36] Chr17:17p13.3-13.1	pathogenic
GRCh38/hg38 17p13.2(chr17:4044302-5943772)x1	copy number loss	See cases [RCV000135548]	Chr17:4044302..5943772 [GRCh38] Chr17:3947596..5847092 [GRCh37] Chr17:3894345..5787816 [NCBI36] Chr17:17p13.2	likely pathogenic
GRCh38/hg38 17p13.2(chr17:4141725-4778120)x1	copy number loss	See cases [RCV000137514]	Chr17:4141725..4778120 [GRCh38] Chr17:4045019..4681415 [GRCh37] Chr17:3991768..4628164 [NCBI36] Chr17:17p13.2	uncertain significance
GRCh38/hg38 17p13.3-13.1(chr17:162016-7697012)x1	copy number loss	See cases [RCV000138214]	Chr17:162016..7697012 [GRCh38] Chr17:45835..7600330 [GRCh37] Chr17:11807..7541055 [NCBI36] Chr17:17p13.3-13.1	pathogenic
GRCh38/hg38 17p13.3-12(chr17:162016-12343901)x3	copy number gain	See cases [RCV000138531]	Chr17:162016..12343901 [GRCh38] Chr17:45835..12247218 [GRCh37] Chr17:11807..12187943 [NCBI36] Chr17:17p13.3-12	pathogenic
GRCh38/hg38 17p13.2(chr17:4092608-5354473)x3	copy number gain	See cases [RCV000139650]	Chr17:4092608..5354473 [GRCh38] Chr17:3995902..5257768 [GRCh37] Chr17:3942651..5198492 [NCBI36] Chr17:17p13.2	likely benign
GRCh38/hg38 17p13.3-13.2(chr17:150732-5935377)x1	copy number loss	See cases [RCV000141658]	Chr17:150732..5935377 [GRCh38] Chr17:525..5838697 [GRCh37] Chr17:525..5779421 [NCBI36] Chr17:17p13.3-13.2	pathogenic
GRCh38/hg38 17p13.3-13.2(chr17:237248-4735533)x1	copy number loss	See cases [RCV000141559]	Chr17:237248..4735533 [GRCh38] Chr17:396627..4638828 [GRCh37] Chr17:87039..4585577 [NCBI36] Chr17:17p13.3-13.2	pathogenic
GRCh38/hg38 17p13.3-12(chr17:150732-14764202)x3	copy number gain	See cases [RCV000142236]	Chr17:150732..14764202 [GRCh38] Chr17:525..14667519 [GRCh37] Chr17:525..14608244 [NCBI36] Chr17:17p13.3-12	pathogenic
GRCh38/hg38 17p13.2(chr17:4141725-4873241)x3	copy number gain	See cases [RCV000143014]	Chr17:4141725..4873241 [GRCh38] Chr17:4045019..4776536 [GRCh37] Chr17:3991768..4722711 [NCBI36] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.2(chr17:4475016-4648525)x1	copy number loss	See cases [RCV000449426]	Chr17:4475016..4648525 [GRCh37] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.3-13.2(chr17:1751557-5378509)x1	copy number loss	See cases [RCV000445994]	Chr17:1751557..5378509 [GRCh37] Chr17:17p13.3-13.2	pathogenic
GRCh37/hg19 17p13.3-13.1(chr17:1113102-6742486)	copy number gain	See cases [RCV000445679]	Chr17:1113102..6742486 [GRCh37] Chr17:17p13.3-13.1	pathogenic
GRCh37/hg19 17p13.2(chr17:4389607-4829150)x3	copy number gain	See cases [RCV000448511]	Chr17:4389607..4829150 [GRCh37] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.3-12(chr17:525-15027737)x3	copy number gain	See cases [RCV000511786]	Chr17:525..15027737 [GRCh37] Chr17:17p13.3-12	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)	copy number gain	See cases [RCV000511439]	Chr17:526..81041938 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-13.2(chr17:47546-6287620)	copy number gain	Chromosome 17P13.3, telomeric, duplication syndrome [RCV000767586]	Chr17:47546..6287620 [GRCh37] Chr17:17p13.3-13.2	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3	copy number gain	See cases [RCV000512441]	Chr17:526..81041938 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-12(chr17:525-11186432)x3	copy number gain	not provided [RCV000683866]	Chr17:525..11186432 [GRCh37] Chr17:17p13.3-12	pathogenic
GRCh37/hg19 17p13.2(chr17:4475016-4884701)x3	copy number gain	not provided [RCV000683882]	Chr17:4475016..4884701 [GRCh37] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.2(chr17:4036861-5174346)x3	copy number gain	not provided [RCV000683881]	Chr17:4036861..5174346 [GRCh37] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3	copy number gain	not provided [RCV000739324]	Chr17:8547..81060040 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3	copy number gain	not provided [RCV000739320]	Chr17:7214..81058310 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3	copy number gain	not provided [RCV000739325]	Chr17:12344..81057996 [GRCh37] Chr17:17p13.3-q25.3	pathogenic
GRCh37/hg19 17p13.2(chr17:3336162-4918458)x1	copy number loss	not provided [RCV000739374]	Chr17:3336162..4918458 [GRCh37] Chr17:17p13.2	likely pathogenic
GRCh37/hg19 17p13.3-13.2(chr17:8547-5627408)x1	copy number loss	See cases [RCV001007429]	Chr17:8547..5627408 [GRCh37] Chr17:17p13.3-13.2	pathogenic
GRCh37/hg19 17p13.2(chr17:3759126-6128911)x1	copy number loss	not provided [RCV000849625]	Chr17:3759126..6128911 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.246C>T (p.Ile82=)	single nucleotide variant	not provided [RCV000888200]	Chr17:4716497 [GRCh38] Chr17:4619792 [GRCh37] Chr17:17p13.2	benign
NM_004313.4(ARRB2):c.864C>T (p.Leu288=)	single nucleotide variant	not provided [RCV000888201]	Chr17:4719367 [GRCh38] Chr17:4622662 [GRCh37] Chr17:17p13.2	benign
GRCh37/hg19 17p13.2(chr17:4113551-5023913)	copy number loss	not specified [RCV002052580]	Chr17:4113551..5023913 [GRCh37] Chr17:17p13.2	uncertain significance
GRCh37/hg19 17p13.2(chr17:4475016-4648525)	copy number loss	not specified [RCV002052581]	Chr17:4475016..4648525 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.38C>T (p.Ser13Leu)	single nucleotide variant	Inborn genetic diseases [RCV002925670]	Chr17:4715027 [GRCh38] Chr17:4618322 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.847C>T (p.Arg283Trp)	single nucleotide variant	Inborn genetic diseases [RCV002950253]	Chr17:4719350 [GRCh38] Chr17:4622645 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.1145C>T (p.Thr382Ile)	single nucleotide variant	Inborn genetic diseases [RCV002984545]	Chr17:4720954 [GRCh38] Chr17:4624249 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.1061C>T (p.Pro354Leu)	single nucleotide variant	Inborn genetic diseases [RCV002804691]	Chr17:4720452 [GRCh38] Chr17:4623747 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.747G>T (p.Gln249His)	single nucleotide variant	Inborn genetic diseases [RCV002855033]	Chr17:4718652 [GRCh38] Chr17:4621947 [GRCh37] Chr17:17p13.2	uncertain significance
NM_004313.4(ARRB2):c.1216G>A (p.Asp406Asn)	single nucleotide variant	Inborn genetic diseases [RCV002897503]	Chr17:4721025 [GRCh38] Chr17:4624320 [GRCh37] Chr17:17p13.2	uncertain significance

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	6542
Count of miRNA genes:	1080
Interacting mature miRNAs:	1410
Transcripts:	ENST00000269260, ENST00000346341, ENST00000381488, ENST00000412477, ENST00000570718, ENST00000570739, ENST00000571206, ENST00000571428, ENST00000571791, ENST00000572457, ENST00000572497, ENST00000572782, ENST00000573886, ENST00000574502, ENST00000574888, ENST00000574954, ENST00000575131, ENST00000575877, ENST00000576235, ENST00000577054
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region

D17S1272

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	17	4,622,896 - 4,623,018	UniSTS	GRCh37
Build 36	17	4,569,645 - 4,569,767	RGD	NCBI36
Celera	17	4,638,076 - 4,638,198	RGD
Cytogenetic Map	17	p13	UniSTS
HuRef	17	4,511,967 - 4,512,089	UniSTS

ARRB2_8210

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	17	4,624,313 - 4,624,990	UniSTS	GRCh37
Build 36	17	4,571,062 - 4,571,739	RGD	NCBI36
Celera	17	4,639,493 - 4,640,170	RGD
HuRef	17	4,513,384 - 4,514,061	UniSTS

RH18345

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	17	4,624,584 - 4,624,764	UniSTS	GRCh37
Build 36	17	4,571,333 - 4,571,513	RGD	NCBI36
Celera	17	4,639,764 - 4,639,944	RGD
Cytogenetic Map	17	p13	UniSTS
HuRef	17	4,513,655 - 4,513,835	UniSTS
GeneMap99-GB4 RH Map	17	42.11	UniSTS
NCBI RH Map	17	54.6	UniSTS

WI-11146

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	17	4,624,534 - 4,624,723	UniSTS	GRCh37
Build 36	17	4,571,283 - 4,571,472	RGD	NCBI36
Celera	17	4,639,714 - 4,639,903	RGD
Cytogenetic Map	17	p13	UniSTS
HuRef	17	4,513,605 - 4,513,794	UniSTS
GeneMap99-GB4 RH Map	17	44.76	UniSTS
Whitehead-RH Map	17	55.3	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

205

Medium

2416

2311

1625

537

1728

395

3481

1223

3525

350

1266

1558

155

1203

1971

Low

470

875

971

195

183

817

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001257328	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001257329	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001257330	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001257331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001330064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_004313	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_199004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NR_047516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_011523858	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017024645	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024450751	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024450752	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_024450753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436064	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436065	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_047436067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002958006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_002958007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB209786	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC091153	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF106941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK097542	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK290951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK297059	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK297181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC007427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC039066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC067368	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC095450	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG723452	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471108	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CP068261	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR450310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CR749218	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ314866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ664180	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	EU883572	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HF583760	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	Z11501	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENST00000269260 ⟹ ENSP00000269260

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,632 - 4,721,497 (+)	Ensembl

RefSeq Acc Id:

ENST00000346341 ⟹ ENSP00000341895

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,634 - 4,721,499 (+)	Ensembl

RefSeq Acc Id:

ENST00000381488 ⟹ ENSP00000370898

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,693 - 4,721,061 (+)	Ensembl

RefSeq Acc Id:

ENST00000412477 ⟹ ENSP00000403701

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,693 - 4,721,496 (+)	Ensembl

RefSeq Acc Id:

ENST00000570718

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,632 - 4,716,539 (+)	Ensembl

RefSeq Acc Id:

ENST00000570739

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,632 - 4,717,941 (+)	Ensembl

RefSeq Acc Id:

ENST00000571206 ⟹ ENSP00000460607

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,715,589 - 4,721,138 (+)	Ensembl

RefSeq Acc Id:

ENST00000571428 ⟹ ENSP00000465877

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,697 - 4,719,418 (+)	Ensembl

RefSeq Acc Id:

ENST00000571791

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,682 - 4,717,062 (+)	Ensembl

RefSeq Acc Id:

ENST00000572457 ⟹ ENSP00000465296

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,643 - 4,721,482 (+)	Ensembl

RefSeq Acc Id:

ENST00000572497 ⟹ ENSP00000458946

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,691 - 4,716,515 (+)	Ensembl

RefSeq Acc Id:

ENST00000572782

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,714,551 - 4,716,002 (+)	Ensembl

RefSeq Acc Id:

ENST00000573886

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,691 - 4,718,370 (+)	Ensembl

RefSeq Acc Id:

ENST00000574502 ⟹ ENSP00000458371

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,596 - 4,719,413 (+)	Ensembl

RefSeq Acc Id:

ENST00000574888

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,655 - 4,716,473 (+)	Ensembl

RefSeq Acc Id:

ENST00000574954 ⟹ ENSP00000466344

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,630 - 4,721,096 (+)	Ensembl

RefSeq Acc Id:

ENST00000575131

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,661 - 4,717,379 (+)	Ensembl

RefSeq Acc Id:

ENST00000575877 ⟹ ENSP00000466857

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,699 - 4,721,496 (+)	Ensembl

RefSeq Acc Id:

ENST00000576235 ⟹ ENSP00000460879

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,710,724 - 4,720,407 (+)	Ensembl

RefSeq Acc Id:

ENST00000577054

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	17	4,717,436 - 4,718,149 (+)	Ensembl

RefSeq Acc Id:

NM_001257328 ⟹ NP_001244257

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTG
TGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCG
CAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCC
ACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCG
TGAGGATGCCCCTGCCCTCTGAGGGCCAGGGGGCTGGGGCTGGGACTGTGTCTGGGGTGGGGAT
ACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGC
GGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGA
ACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTC
AGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGAC
AAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACCA
AGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCGC
CCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATTC
TGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGG
ATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAA
CAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGC
GGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCC
TCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATT
TGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAG
GGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGG
GATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGC
CCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATC
CCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTC
TGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACA
GTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAA
CACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCC
GTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_001257329 ⟹ NP_001244258

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTG
TGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCG
CAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCC
ACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCA
TACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTG
CGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGG
AACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTT
CAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGA
CAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACC
AAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCG
CCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGCGTGAAGGAGGGTGCCAACA
AGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGG
GGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTC
CCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTG
ATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGG
GATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGA
TGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCC
CTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCC
CCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTG
CTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGT
GAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACA
CCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGT
TTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_001257330 ⟹ NP_001244259

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTG
TGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCG
CAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCC
ACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCA
TACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTG
CGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGG
AACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTT
CAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGA
CAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACC
AAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCG
CCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATT
CTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTG
GATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCA
ACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGG
CGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCC
CTCCCCAGACCCCAGTCAGCACCCACCCCCACACCCCCTCTTCCCGTCCCCCCAGCCGCTCCGG
AGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGA
CATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGAT
CAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGG
ATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAG
CTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTC
TTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGC
AAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAA
GGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCC
CCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAG
AAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_001257331 ⟹ NP_001244260

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATG
TGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCC
CAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCC
CACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAG
AGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGA
AGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAG
AAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGC
ACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCA
CGTCACCAACAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGAC
ATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGG
TATCTCCCAGCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGA
GAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACC
ATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGA
AGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAA
GCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCACCCACCCCCACACCCCCTCTTCCC
GTCCCCCCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCA
ACTATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAA
GGATGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGT
TGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTC
CCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAG
ATACACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTC
CAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAG
AGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCC
ATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTT
GTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_001330064 ⟹ NP_001316993

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGCTCACCGTGTACTTG
GGCAAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGTGTTTGTGACCCTCACCT
GCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTT
CATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAG
GACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATC
TTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTT
TGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGG
CTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCA
CACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTA
CTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACCAAGACCGTCAAG
AAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGT
GTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTA
CACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTC
AAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGC
TGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTC
TGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGACCC
CAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACT
ATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGA
TGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGG
GAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCT
TCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATA
CACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAG
CCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGG
AGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCCATT
ATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTT
TCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_004313 ⟹ NP_004304

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	ENTREZGENE
Build 36	17	4,560,538 - 4,571,544 (+)	NCBI Archive
HuRef	17	4,502,952 - 4,513,866 (+)	ENTREZGENE
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTG
TGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCG
CAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCC
ACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCA
TACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTG
CGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGG
AACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTT
CAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGA
CAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACC
AAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCG
CCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATT
CTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTG
GATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCA
ACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGG
CGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCC
CTCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAAT
TTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAA
GGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGG
GGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAG
CCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCAT
CCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCT
CTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGAC
AGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCA
ACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGC
CGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

NM_199004 ⟹ NP_945355

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	ENTREZGENE
Build 36	17	4,560,538 - 4,571,544 (+)	NCBI Archive
HuRef	17	4,502,952 - 4,513,866 (+)	ENTREZGENE
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGGGTCTTCAAGAAGTC
GAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAA
GTGGACCCTGTAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATG
TGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCC
CAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCC
CACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAG
AGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGA
AGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAG
AAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGC
ACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCA
CGTCACCAACAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGAC
ATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGG
TATCTCCCAGCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGA
GAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACC
ATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGA
AGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAA
GCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCCTGTG
GACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACT
TTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGC
GGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGT
CAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCC
TTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCAT
TAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCT
AAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCC
TACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGA
GACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACT
AAGCA

hide sequence

RefSeq Acc Id:

NR_047516

RefSeq Status:

REVIEWED

Type:

NON-CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI
GRCh37	17	4,613,789 - 4,624,795 (+)	NCBI
HuRef	17	4,502,952 - 4,513,866 (+)	NCBI
CHM1_1	17	4,622,557 - 4,633,518 (+)	NCBI
T2T-CHM13v2.0	17	4,600,371 - 4,611,146 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGCTCACCGTGTACTTG
GGCAAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGATGGCGTGGTGCTTGTGG
ACCCTGACTACCTGAAGGACCGCAAAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCG
TGAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCC
TTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGC
TGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACT
GCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGT
GCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGC
AGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTC
TGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTC
AATGTAAATGTCCACGTCACCAACAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGA
GACAGTACGCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGA
ACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTC
AGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACC
TGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTA
CAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTT
CTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCCGCTCCGGAGA
CAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACAT
TGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAA
CTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATT
AAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTT
CTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTG
CTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAG
CTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGG
GGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCA
TTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAA
ATAAATCTTTTACTAAGCA

hide sequence

RefSeq Acc Id:

XM_011523858 ⟹ XP_011522160

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,759 - 4,721,497 (+)	NCBI

Sequence:

show sequence

GTGGGGCCACGCGGCGGGGCATGGGCGGCGGCTCGGGGCGGGGGCTGGGACGGTCCCAGACGAG
GGCGCAGCGGAGAGGATCTGGGGGCCGGACGCCTGGGTCCCTAGGGACAGCCATCCGGGGCCGC
ACGCGCAGGGTCTTCAAGAAGTCGAGCCCTAACTGCAAGCTCACCGTGTACTTGGGCAAGCGGG
ACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTA
CCTGAAGGACCGCAAAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTG
GATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGG
TGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCA
TGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGC
CCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCAC
TAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCC
GGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCC
CTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATG
TCCACGTCACCAACAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGC
CGACATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGAC
CAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACC
GGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAG
CACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAG
GTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACC
CCAAGCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCAGCCGCTCCGGAGACAGATGTCCC
TGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAG
GACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGG
AAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCA
CTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAA
TCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGG
GCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCAT
ACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAA
CTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAG
AGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTT
TACTAAGCATGA

hide sequence

RefSeq Acc Id:

XM_017024645 ⟹ XP_016880134

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,715,186 - 4,721,497 (+)	NCBI

Sequence:

show sequence

TTCCTTCCCTCCTGAAGCCCCTTGCCGCAGAGGCTGCTCAGCCTGAGCCAGCCACAGGGCTGGG
TGGGGCAGGCTTGGGTCCCCAAGCAAGACCACAGAGGAGGAGGCCAAAAGCAAGCCATGTGCCT
GTAGCCCTCCTAGGAGCCAACCCAAGCTCACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCA
CCTGGACAAAGTGGACCCTGTAGATGGCGTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGC
AAAGTGTTTGTGACCCTCACCTGCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCT
TGTCCTTCCGCAAAGACCTGTTCATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACC
CCGGCCCCCCACCCGCCTGCAGGACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTC
TTCTTCACCATACCCCAGAATCTTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAG
GAAAGGCCTGCGGCGTAGACTTTGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAG
CCACAAAAGGAACTCTGTGCGGCTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGC
CCCCAGCCTTCAGCCGAAACCACACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGG
CTTCCCTGGACAAGGAGCTGTACTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAA
CAACTCCACCAAGACCGTCAAGAAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTC
TTCAGCACCGCCCAGTACAAGTGTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCA
GCTCCACATTCTGTAAGGTGTACACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGG
TCTCGCCCTGGATGGGAAACTCAAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAG
GAGGGTGCCAACAAGGAGGTGCTGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGG
TGTCTCGAGGCGGGGATGTCTCTGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGA
CCACATCCCCCTCCCCAGACCCCAGTCAGCACCCACCCCCACACCCCCTCTTCCCGTCCCCCCA
GCCGCTCCGGAGACAGATGTCCCTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCA
CAGATGATGACATTGTGTTTGAGGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGA
CTATGATGATCAACTCTGCTAGGAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGG
TGAGGGCAGGATTAAGATCCCCACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCT
CACCTGGAAGCTTCTTCAACCAATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACT
GGACCCTCTCTTGCTGAATGTGGGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGC
CGTGGGTGGCAAGCTGTGTTCATACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGAC
AGGAGGGAAAGGGGGAGACAAAACTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACT
CTCTCTGCCCCCATTCCTTCAAGAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAG
CATAAAGAAGAAAATAAATCTTTTACTAAGCATGA

hide sequence

RefSeq Acc Id:

XM_024450752 ⟹ XP_024306520

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI

Sequence:

show sequence

AGGGCGCGCGTGCGCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCG
AGCGAGCCGCGAACCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGCT
CACCGTGTACTTGGGCAAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGATGGC
GTGGTGCTTGTGGACCCTGACTACCTGAAGGACCGCAAAGTGTTTGTGACCCTCACCTGCGCCT
TCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTTCATCGC
CACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAGGACCGG
CTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATCTTCCAT
GCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTTTGAGAT
TCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGGCTGGTG
ATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCACACGCC
ACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTACTACCA
TGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACCAAGACCGTCAAGAAGATC
AAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGTGTCCTG
TGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTACACCAT
AACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTCAAGCAC
GAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGCTGGGAA
TCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTCTGTGGA
GCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGACCCCAGTCA
GCACCCACCCCCACACCCCCTCTTCCCGTCCCCCCAGCCGCTCCGGAGACAGATGTCCCTGTGG
ACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGAGGACTT
TGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAGGAAGCG
GGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCCACTGTC
AATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCAATCCCT
TCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTGGGCATT
AATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCATACCTA
AATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAAACTCCT
ACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAAGAGGAG
ACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTTTTACTA
AGCATGA

hide sequence

RefSeq Acc Id:

XM_024450753 ⟹ XP_024306521

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI

Sequence:

show sequence

GCATTGGCGCGGGGAGGAGCAGGGATCTTGGCAGCGGGCGAGGAGGCTGCGAGCGAGCCGCGAA
CCGAGCGGGCGGCGGGCGCGCGCACCATGGGGGAGAAACCCGGGACCAGCTCACCGTGTACTTG
GGCAAGCGGGACTTCGTAGATCACCTGGACAAAGTGGACCCTGTAGTGTTTGTGACCCTCACCT
GCGCCTTCCGCTATGGCCGTGAAGACCTGGATGTGCTGGGCTTGTCCTTCCGCAAAGACCTGTT
CATCGCCACCTACCAGGCCTTCCCCCCGGTGCCCAACCCACCCCGGCCCCCCACCCGCCTGCAG
GACCGGCTGCTGAGGAAGCTGGGCCAGCATGCCCACCCCTTCTTCTTCACCATACCCCAGAATC
TTCCATGCTCCGTCACACTGCAGCCAGGCCCAGAGGATACAGGAAAGGCCTGCGGCGTAGACTT
TGAGATTCGAGCCTTCTGTGCTAAATCACTAGAAGAGAAAAGCCACAAAAGGAACTCTGTGCGG
CTGGTGATCCGAAAGGTGCAGTTCGCCCCGGAGAAACCCGGCCCCCAGCCTTCAGCCGAAACCA
CACGCCACTTCCTCATGTCTGACCGGTCCCTGCACCTCGAGGCTTCCCTGGACAAGGAGCTGTA
CTACCATGGGGAGCCCCTCAATGTAAATGTCCACGTCACCAACAACTCCACCAAGACCGTCAAG
AAGATCAAAGTCTCTGTGAGACAGTACGCCGACATCTGCCTCTTCAGCACCGCCCAGTACAAGT
GTCCTGTGGCTCAACTCGAACAAGATGACCAGGTATCTCCCAGCTCCACATTCTGTAAGGTGTA
CACCATAACCCCACTGCTCAGCGACAACCGGGAGAAGCGGGGTCTCGCCCTGGATGGGAAACTC
AAGCACGAGGACACCAACCTGGCTTCCAGCACCATCGTGAAGGAGGGTGCCAACAAGGAGGTGC
TGGGAATCCTGGTGTCCTACAGGGTCAAGGTGAAGCTGGTGGTGTCTCGAGGCGGGGATGTCTC
TGTGGAGCTGCCTTTTGTTCTTATGCACCCCAAGCCCCACGACCACATCCCCCTCCCCAGACCC
CAGTCAGCACCCACCCCCACACCCCCTCTTCCCGTCCCCCCAGCCGCTCCGGAGACAGATGTCC
CTGTGGACACCAACCTCATTGAATTTGATACCAACTATGCCACAGATGATGACATTGTGTTTGA
GGACTTTGCCCGGCTTCGGCTGAAGGGGATGAAGGATGACGACTATGATGATCAACTCTGCTAG
GAAGCGGGGTGGGAAGAAGGGAGGGGATGGGGTTGGGAGAGGTGAGGGCAGGATTAAGATCCCC
ACTGTCAATGGGGGATTGTCCCAGCCCCTCTTCCCTTCCCCTCACCTGGAAGCTTCTTCAACCA
ATCCCTTCACACTCTCTCCCCCATCCCCCCAAGATACACACTGGACCCTCTCTTGCTGAATGTG
GGCATTAATTTTTTGACTGCAGCTCTGCTTCTCCAGCCCCGCCGTGGGTGGCAAGCTGTGTTCA
TACCTAAATTTTCTGGAAGGGGACAGTGAAAAGAGGAGTGACAGGAGGGAAAGGGGGAGACAAA
ACTCCTACTCTCAACCTCACACCAACACCTCCCATTATCACTCTCTCTGCCCCCATTCCTTCAA
GAGGAGACCCTTTGGGGACAAGGCCGTTTCTTTGTTTCTGAGCATAAAGAAGAAAATAAATCTT
TTACTAAGCATGA

hide sequence

RefSeq Acc Id:

XM_047436062 ⟹ XP_047292018

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,811 - 4,721,497 (+)	NCBI

RefSeq Acc Id:

XM_047436063 ⟹ XP_047292019

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,811 - 4,721,497 (+)	NCBI

RefSeq Acc Id:

XM_047436064 ⟹ XP_047292020

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,811 - 4,721,497 (+)	NCBI

RefSeq Acc Id:

XM_047436065 ⟹ XP_047292021

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,811 - 4,721,497 (+)	NCBI

RefSeq Acc Id:

XM_047436066 ⟹ XP_047292022

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI

RefSeq Acc Id:

XM_047436067 ⟹ XP_047292023

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,632 - 4,721,497 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001244257	(Get FASTA)	NCBI Sequence Viewer
	NP_001244258	(Get FASTA)	NCBI Sequence Viewer
	NP_001244259	(Get FASTA)	NCBI Sequence Viewer
	NP_001244260	(Get FASTA)	NCBI Sequence Viewer
	NP_001316993	(Get FASTA)	NCBI Sequence Viewer
	NP_004304	(Get FASTA)	NCBI Sequence Viewer
	NP_945355	(Get FASTA)	NCBI Sequence Viewer
	XP_011522160	(Get FASTA)	NCBI Sequence Viewer
	XP_016880134	(Get FASTA)	NCBI Sequence Viewer
	XP_024306520	(Get FASTA)	NCBI Sequence Viewer
	XP_024306521	(Get FASTA)	NCBI Sequence Viewer
	XP_047292018	(Get FASTA)	NCBI Sequence Viewer
	XP_047292019	(Get FASTA)	NCBI Sequence Viewer
	XP_047292020	(Get FASTA)	NCBI Sequence Viewer
	XP_047292021	(Get FASTA)	NCBI Sequence Viewer
	XP_047292022	(Get FASTA)	NCBI Sequence Viewer
	XP_047292023	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC99468	(Get FASTA)	NCBI Sequence Viewer
	AAH07427	(Get FASTA)	NCBI Sequence Viewer
	AAH67368	(Get FASTA)	NCBI Sequence Viewer
	ABC40725	(Get FASTA)	NCBI Sequence Viewer
	ABG47460	(Get FASTA)	NCBI Sequence Viewer
	ACG60646	(Get FASTA)	NCBI Sequence Viewer
	BAC05094	(Get FASTA)	NCBI Sequence Viewer
	BAD93023	(Get FASTA)	NCBI Sequence Viewer
	BAF83640	(Get FASTA)	NCBI Sequence Viewer
	BAG59581	(Get FASTA)	NCBI Sequence Viewer
	BAG59672	(Get FASTA)	NCBI Sequence Viewer
	CAA77577	(Get FASTA)	NCBI Sequence Viewer
	CAG29306	(Get FASTA)	NCBI Sequence Viewer
	CAH18075	(Get FASTA)	NCBI Sequence Viewer
	CCQ43257	(Get FASTA)	NCBI Sequence Viewer
	EAW90419	(Get FASTA)	NCBI Sequence Viewer
	EAW90420	(Get FASTA)	NCBI Sequence Viewer
	EAW90421	(Get FASTA)	NCBI Sequence Viewer
	EAW90422	(Get FASTA)	NCBI Sequence Viewer
	P32121	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_004304 ⟸ NM_004313
- Peptide Label:	isoform 1
- UniProtKB:	Q9UEQ6 (UniProtKB/Swiss-Prot), P32121 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRY GREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSV TLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFL MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDD DIVFEDFARLRLKGMKDDDYDDQLC hide sequence

RefSeq Acc Id:	NP_945355 ⟸ NM_199004
- Peptide Label:	isoform 2
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVVFVTLTCAFRYGREDLDVLGLSFRKD LFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGV DFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKE LYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCK VYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGD VSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGM KDDDYDDQLC hide sequence

RefSeq Acc Id:	NP_001244257 ⟸ NM_001257328
- Peptide Label:	isoform 3
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot), Q59EM5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRY GREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTVRMPLPSEG QGAGAGTVSGVGIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRK VQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVS VRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDT NLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAP ETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC hide sequence

RefSeq Acc Id:	NP_001244259 ⟸ NM_001257330
- Peptide Label:	isoform 5
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRY GREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSV TLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFL MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAPTPTPPLPVPPAAPETDVPVDTN LIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC hide sequence

RefSeq Acc Id:	NP_001244258 ⟸ NM_001257329
- Peptide Label:	isoform 4
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot), K7ENA6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTCAFRY GREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSV TLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFL MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ LEQDDQREGGCQQGGAGNPGVLQGQGEAGGVSRRGCLCGAAFCSYAPQAPRPHPPPQTPVSRSG DRCPCGHQPH hide sequence

RefSeq Acc Id:	NP_001244260 ⟸ NM_001257331
- Peptide Label:	isoform 6
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVVFVTLTCAFRYGREDLDVLGLSFRKD LFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGV DFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKE LYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCK VYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGD VSVELPFVLMHPKPHDHIPLPRPQSAPTPTPPLPVPPAAPETDVPVDTNLIEFDTNYATDDDIV FEDFARLRLKGMKDDDYDDQLC hide sequence

RefSeq Acc Id:

XP_011522160 ⟸ XM_011523858

- Peptide Label:

isoform X2

- Sequence:

show sequence

MGGGSGRGLGRSQTRAQRRGSGGRTPGSLGTAIRGRTRRVFKKSSPNCKLTVYLGKRDFVDHLD
KVDPVDGVVLVDPDYLKDRKVFVTLTCAFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRP
PTRLQDRLLRKLGQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHK
RNSVRLVIRKVQFAPEKPGPQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNS
TKTVKKIKVSVRQYADICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLA
LDGKLKHEDTNLASSTIVKEGANKEVLGILVSYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHI
PLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC

hide sequence

RefSeq Acc Id:

XP_016880134 ⟸ XM_017024645

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ
LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV
SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAPTPTPPLPVPPAAPETDVPVDTN
LIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC

hide sequence

RefSeq Acc Id:	NP_001316993 ⟸ NM_001330064
- Peptide Label:	isoform 7
- UniProtKB:	P32121 (UniProtKB/Swiss-Prot), Q68DZ5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAAPETDVPVDTNLIEFDTNYATDD DIVFEDFARLRLKGMKDDDYDDQLC hide sequence

RefSeq Acc Id:

XP_024306520 ⟸ XM_024450752

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ
LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV
SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAPTPTPPLPVPPAAPETDVPVDTN
LIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC

hide sequence

RefSeq Acc Id:

XP_024306521 ⟸ XM_024450753

- Peptide Label:

isoform X1

- Sequence:

show sequence

MSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYADICLFSTAQYKCPVAQ
LEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTNLASSTIVKEGANKEVLGILV
SYRVKVKLVVSRGGDVSVELPFVLMHPKPHDHIPLPRPQSAPTPTPPLPVPPAAPETDVPVDTN
LIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC

hide sequence

RefSeq Acc Id:

ENSP00000341895 ⟸ ENST00000346341

RefSeq Acc Id:

ENSP00000269260 ⟸ ENST00000269260

RefSeq Acc Id:

ENSP00000403701 ⟸ ENST00000412477

RefSeq Acc Id:

ENSP00000460607 ⟸ ENST00000571206

RefSeq Acc Id:

ENSP00000465877 ⟸ ENST00000571428

RefSeq Acc Id:

ENSP00000458946 ⟸ ENST00000572497

RefSeq Acc Id:

ENSP00000465296 ⟸ ENST00000572457

RefSeq Acc Id:

ENSP00000466344 ⟸ ENST00000574954

RefSeq Acc Id:

ENSP00000458371 ⟸ ENST00000574502

RefSeq Acc Id:

ENSP00000466857 ⟸ ENST00000575877

RefSeq Acc Id:

ENSP00000460879 ⟸ ENST00000576235

RefSeq Acc Id:

ENSP00000370898 ⟸ ENST00000381488

RefSeq Acc Id:	XP_047292022 ⟸ XM_047436066
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_047292023 ⟸ XM_047436067
- Peptide Label:	isoform X3
- UniProtKB:	Q68DZ5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_047292018 ⟸ XM_047436062
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_047292021 ⟸ XM_047436065
- Peptide Label:	isoform X4

RefSeq Acc Id:	XP_047292019 ⟸ XM_047436063
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_047292020 ⟸ XM_047436064
- Peptide Label:	isoform X3
- UniProtKB:	Q68DZ5 (UniProtKB/TrEMBL)

Protein Domains

Arrestin C-terminal-like Arrestin-like N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P32121-F1-model_v2	AlphaFold	P32121	1-409	view protein structure

Promoters

RGD ID:

6793753

Promoter ID:

HG_KWN:24741

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell, CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, K562, Lymphoblastoid, NB4

Transcripts:

ENST00000381488, NM_004313, NM_199004, UC002FYM.1, UC002FYN.1, UC010CKQ.1

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	17	4,560,131 - 4,560,787 (+)	MPROMDB

RGD ID:

7233429

Promoter ID:

EPDNEW_H22460

Type:

initiation region

Name:

ARRB2_2

Description:

arrestin beta 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H22461 EPDNEW_H22463

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,427 - 4,710,487	EPDNEW

RGD ID:

7233431

Promoter ID:

EPDNEW_H22461

Type:

initiation region

Name:

ARRB2_1

Description:

arrestin beta 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H22460 EPDNEW_H22463

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,710,682 - 4,710,742	EPDNEW

RGD ID:

7233435

Promoter ID:

EPDNEW_H22463

Type:

initiation region

Name:

ARRB2_3

Description:

arrestin beta 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H22460 EPDNEW_H22461

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	17	4,714,891 - 4,714,951	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:712	AgrOrtholog
COSMIC	ARRB2	COSMIC
Ensembl Genes	ENSG00000141480	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein	ENSP00000269260	ENTREZGENE
	ENSP00000269260.2	UniProtKB/Swiss-Prot
	ENSP00000341895	ENTREZGENE
	ENSP00000341895.2	UniProtKB/Swiss-Prot
	ENSP00000370898	ENTREZGENE
	ENSP00000370898.6	UniProtKB/Swiss-Prot
	ENSP00000403701	ENTREZGENE
	ENSP00000403701.3	UniProtKB/Swiss-Prot
	ENSP00000458371.1	UniProtKB/TrEMBL
	ENSP00000458946.1	UniProtKB/TrEMBL
	ENSP00000460607.1	UniProtKB/TrEMBL
	ENSP00000460879.1	UniProtKB/TrEMBL
	ENSP00000465296	ENTREZGENE
	ENSP00000465296.1	UniProtKB/TrEMBL
	ENSP00000465877.1	UniProtKB/TrEMBL
	ENSP00000466344.1	UniProtKB/TrEMBL
	ENSP00000466857	ENTREZGENE
	ENSP00000466857.1	UniProtKB/TrEMBL
Ensembl Transcript	ENST00000269260	ENTREZGENE
	ENST00000269260.7	UniProtKB/Swiss-Prot
	ENST00000346341	ENTREZGENE
	ENST00000346341.6	UniProtKB/Swiss-Prot
	ENST00000381488	ENTREZGENE
	ENST00000381488.10	UniProtKB/Swiss-Prot
	ENST00000412477	ENTREZGENE
	ENST00000412477.7	UniProtKB/Swiss-Prot
	ENST00000571206.1	UniProtKB/TrEMBL
	ENST00000571428.5	UniProtKB/TrEMBL
	ENST00000572457	ENTREZGENE
	ENST00000572457.5	UniProtKB/TrEMBL
	ENST00000572497.5	UniProtKB/TrEMBL
	ENST00000574502.5	UniProtKB/TrEMBL
	ENST00000574954.5	UniProtKB/TrEMBL
	ENST00000575877	ENTREZGENE
	ENST00000575877.5	UniProtKB/TrEMBL
	ENST00000576235.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.640	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.40.840	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000141480	GTEx
HGNC ID	HGNC:712	ENTREZGENE
Human Proteome Map	ARRB2	Human Proteome Map
InterPro	Arrestin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin-like_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin_C-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_E-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:409	UniProtKB/Swiss-Prot
NCBI Gene	409	ENTREZGENE
OMIM	107941	OMIM
PANTHER	BETA-ARRESTIN-2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11792	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Arrestin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Arrestin_N	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA60	PharmGKB
PRINTS	ARRESTIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	ARRESTINS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	Arrestin_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF81296	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	ARRB2_HUMAN	UniProtKB/Swiss-Prot
	I3L0V6_HUMAN	UniProtKB/TrEMBL
	I3L1M6_HUMAN	UniProtKB/TrEMBL
	I3L412_HUMAN	UniProtKB/TrEMBL
	K7EL17_HUMAN	UniProtKB/TrEMBL
	K7ENA6	ENTREZGENE, UniProtKB/TrEMBL
	L8ECB1_HUMAN	UniProtKB/TrEMBL
	P32121	ENTREZGENE
	Q59EM5	ENTREZGENE, UniProtKB/TrEMBL
	Q68DZ5	ENTREZGENE, UniProtKB/TrEMBL
	Q9UEQ6	ENTREZGENE
UniProt Secondary	B4DLW0	UniProtKB/Swiss-Prot
	B5B0C0	UniProtKB/Swiss-Prot
	B7WPL3	UniProtKB/Swiss-Prot
	D3DTK2	UniProtKB/Swiss-Prot
	E7EMN1	UniProtKB/TrEMBL
	H0Y688	UniProtKB/Swiss-Prot
	Q0Z8D3	UniProtKB/Swiss-Prot
	Q2PP19	UniProtKB/Swiss-Prot
	Q6ICT3	UniProtKB/Swiss-Prot
	Q8N7Y2	UniProtKB/Swiss-Prot
	Q9UEQ6	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-04-04	ARRB2	arrestin beta 2		arrestin, beta 2	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)