GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | ARRB2 | multiple interactions | EXP | | 6480464 | CTD | ARRB2 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK1 protein]]; ARRB2 protein promotes the reaction [carvedilol promotes the reaction [[ADRB1 protein co-treated with EGFR protein] results in increased phosphorylation of MAPK3 protein]]; ARRB2 protein promotes the reaction [carvedilol results in increased phosphorylation of MAPK1 protein]; ARRB2 protein promotes the reaction [carvedilol results in increased phosphorylation of MAPK3 protein]; carvedilol promotes the reaction [ADRB1 protein binds to ARRB2 protein]; carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]; ICI 118551 inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]]; Propranolol inhibits the reaction [carvedilol promotes the reaction [ADRB2 protein binds to ARRB2 protein]] | PMID:17925438 PMID:18787115 | ARRB2 | affects localization | ISO | Arrb2 (Rattus norvegicus) | 6480464 | CTD | carvedilol affects the localization of ARRB2 protein | PMID:21078978 | ARRB2 | multiple interactions | ISO | Arrb2 (Rattus norvegicus) | 6480464 | CTD | ARRB2 promotes the reaction [carvedilol results in increased uptake of Calcium] | PMID:21078978 | | ||||||||||||||||||||||
| Go Back to source page | Continue to Ontology report |