Arrb2 (arrestin, beta 2) - Rat Genome Database

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Gene: Arrb2 (arrestin, beta 2) Mus musculus
Analyze
Symbol: Arrb2
Name: arrestin, beta 2
RGD ID: 10192
MGI Page MGI
Description: Enables protein kinase B binding activity. Involved in several processes, including adult walking behavior; negative regulation of cytokine production; and positive regulation of cell communication. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway and regulation of protein phosphorylation. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in glioblastoma; heroin dependence; nicotine dependence; and opiate dependence. Orthologous to human ARRB2 (arrestin beta 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A; AI326910; Arr3; arrestin 3; arrestin beta-2; AW122872; beta arr2; beta-arrestin-2; beta-arrestin2; RP23-42P20.7
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,323,051 - 70,331,654 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,323,461 - 70,331,654 (+)EnsemblGRCm39 Ensembl
GRCm381170,432,485 - 70,440,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,432,635 - 70,440,828 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,246,155 - 70,254,176 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,248,893 - 70,257,018 (+)NCBIMGSCv36mm8
Celera1177,978,619 - 77,986,640 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(D-Ala(2)-mephe(4)-gly-ol(5))enkephalin  (EXP,ISO)
1,1-dichloroethene  (EXP)
1,2-dichloroethane  (EXP)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2-arachidonoylglycerol  (ISO)
3',5'-cyclic AMP  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
acetamide  (ISO)
acrolein  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
alprenolol  (ISO)
ammonium chloride  (ISO)
anandamide  (ISO)
antirheumatic drug  (ISO)
ATP  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP,ISO)
caffeine  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
carteolol  (ISO)
carvedilol  (ISO)
celastrol  (ISO)
CGP 52608  (ISO)
chrysin  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (EXP)
DDE  (ISO)
dextran sulfate  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichlorine  (ISO)
dobutamine  (ISO)
dopamine  (ISO)
Endomorphin-2  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fentanyl  (ISO)
fenthion  (EXP)
flavonoids  (ISO)
fluoxetine  (EXP)
gentamycin  (ISO)
hydromorphone  (ISO)
ICI 118551  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
leukotriene D4  (ISO)
methamphetamine  (ISO)
methapyrilene  (ISO)
methidathion  (EXP)
methoxyacetic acid  (ISO)
methylmercury chloride  (ISO)
metoprolol  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
Monobutylphthalate  (ISO)
morphine  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (ISO)
nitrates  (EXP)
ozone  (ISO)
pamoic acid  (ISO)
paracetamol  (EXP,ISO)
pirinixic acid  (EXP)
propranolol  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
S-nitroso-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
superoxide  (EXP)
T-2 toxin  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
tungsten  (EXP)
valproic acid  (ISO)
vancomycin  (EXP)
WIN 55212-2  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult walking behavior  (IMP)
cell chemotaxis  (IEA,ISO)
circadian rhythm  (ISO)
desensitization of G protein-coupled receptor signaling pathway  (ISO)
detection of temperature stimulus involved in sensory perception of pain  (ISO)
endocytosis  (ISO)
follicle-stimulating hormone signaling pathway  (ISO)
G protein-coupled receptor internalization  (IBA,IEA,ISO)
G protein-coupled receptor signaling pathway  (ISO)
modulation of chemical synaptic transmission  (IDA,IMP)
negative regulation of canonical NF-kappaB signal transduction  (IEA,ISO)
negative regulation of GTPase activity  (ISO)
negative regulation of interleukin-1 beta production  (IMP)
negative regulation of interleukin-12 production  (IMP)
negative regulation of interleukin-6 production  (IMP)
negative regulation of natural killer cell mediated cytotoxicity  (IEA,ISO)
negative regulation of neuron apoptotic process  (ISO)
negative regulation of NF-kappaB transcription factor activity  (ISO)
negative regulation of opioid receptor signaling pathway  (ISO)
negative regulation of protein ubiquitination  (IEA,ISO)
negative regulation of release of cytochrome c from mitochondria  (ISO)
negative regulation of smooth muscle cell apoptotic process  (ISO)
negative regulation of toll-like receptor signaling pathway  (IMP)
negative regulation of tumor necrosis factor production  (IMP)
positive regulation of calcium ion transport  (ISO)
positive regulation of cardiac muscle cell differentiation  (IDA)
positive regulation of collagen biosynthetic process  (ISO)
positive regulation of DNA biosynthetic process  (ISO)
positive regulation of epithelial cell apoptotic process  (ISO)
positive regulation of ERK1 and ERK2 cascade  (IBA,IEA,ISO)
positive regulation of gene expression  (IDA)
positive regulation of glial cell proliferation  (ISO)
positive regulation of opioid receptor signaling pathway  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of peptidyl-tyrosine phosphorylation  (ISO)
positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction  (IMP,ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of receptor internalization  (ISO,ISS)
positive regulation of synaptic transmission, dopaminergic  (IMP)
postsynaptic signal transduction  (IDA,IMP)
proteasome-mediated ubiquitin-dependent protein catabolic process  (IEA,ISO)
protein transport  (IEA)
protein ubiquitination  (IEA,ISO)
receptor internalization  (ISO)
regulation of G protein-coupled receptor signaling pathway  (IMP,ISO)
regulation of protein phosphorylation  (IDA,IGI)
response to morphine  (ISO)
transcription by RNA polymerase II  (IEA,ISO)
transforming growth factor beta receptor signaling pathway  (IEA,ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. β-arrestin 2 stimulates degradation of HIF-1α and modulates tumor progression of glioblastoma. Bae WY, etal., Cell Death Differ. 2021 Nov;28(11):3092-3104. doi: 10.1038/s41418-021-00802-2. Epub 2021 May 18.
2. Beta-arrestins: multifunctional cellular mediators. Barki-Harrington L and Rockman HA, Physiology (Bethesda). 2008 Feb;23:17-22.
3. The physiology, signaling, and pharmacology of dopamine receptors. Beaulieu JM and Gainetdinov RR, Pharmacol Rev. 2011 Mar;63(1):182-217. doi: 10.1124/pr.110.002642. Epub 2011 Feb 8.
4. Reactive oxygen species are involved in regulating hypocontractility of mesenteric artery to norepinephrine in cirrhotic rats with portal hypertension. Chen W, etal., Int J Biol Sci. 2014 Mar 15;10(4):386-95. doi: 10.7150/ijbs.8081. eCollection 2014.
5. Gender related alterations of beta-adrenoceptor mechanisms in heart failure due to arteriovenous fistula. Dent MR, etal., J Cell Physiol. 2011 Oct 20. doi: 10.1002/jcp.23058.
6. GRK mythology: G-protein receptor kinases in cardiovascular disease. Dorn GW 2nd J Mol Med (Berl). 2009 May;87(5):455-63. Epub 2009 Feb 20.
7. Decreased immunodensities of micro-opioid receptors, receptor kinases GRK 2/6 and beta-arrestin-2 in postmortem brains of opiate addicts. Ferrer-Alcón M, etal., Brain Res Mol Brain Res. 2004 Feb 5;121(1-2):114-22. doi: 10.1016/j.molbrainres.2003.11.009.
8. Defective lymphocyte chemotaxis in beta-arrestin2- and GRK6-deficient mice. Fong AM, etal., Proc Natl Acad Sci U S A 2002 May 28;99(11):7478-83.
9. Corticotropin releasing factor (CRF) receptor signaling in the central nervous system: new molecular targets. Hauger RL, etal., CNS Neurol Disord Drug Targets. 2006 Aug;5(4):453-79.
10. Vascular dysfunction in human and rat cirrhosis: role of receptor-desensitizing and calcium-sensitizing proteins. Hennenberg M, etal., Hepatology. 2007 Feb;45(2):495-506.
11. β-Arrestin 2 (ARRB2) Polymorphism is Associated With Adverse Consequences of Chronic Heroin Use. Karavidha KK, etal., Am J Addict. 2021 Jul;30(4):351-357. doi: 10.1111/ajad.13150. Epub 2021 Mar 30.
12. Chrysin abrogates early hepatocarcinogenesis and induces apoptosis in N-nitrosodiethylamine-induced preneoplastic nodules in rats. Khan MS, etal., Toxicol Appl Pharmacol. 2011 Feb 15;251(1):85-94. Epub 2010 Dec 15.
13. Effects of Chinese Fructus Mume formula and its separated prescription extract on insulin resistance in type 2 diabetic rats. Li JB, etal., J Huazhong Univ Sci Technolog Med Sci. 2013 Dec;33(6):877-85. doi: 10.1007/s11596-013-1215-7. Epub 2013 Dec 13.
14. Improvement of morphine-mediated analgesia by inhibition of β-arrestin2 expression in mice periaqueductal gray matter. Li Y, etal., Int J Mol Sci. 2009 Mar;10(3):954-63. doi: 10.3390/ijms10030954. Epub 2009 Mar 5.
15. Impact of SNP-SNP interaction among ABCB1, ARRB2, DRD1 and OPRD1 on methadone dosage requirement in Han Chinese patients. Luo R, etal., Pharmacogenomics. 2017 Dec;18(18):1659-1670. doi: 10.2217/pgs-2017-0072. Epub 2017 Nov 27.
16. Disrupted circadian expression of β-arrestin 2 affects reward-related µ-opioid receptor function in alcohol dependence. Meinhardt MW, etal., J Neurochem. 2022 Feb;160(4):454-468. doi: 10.1111/jnc.15559. Epub 2022 Jan 4.
17. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
18. MGDs mouse GO annotations MGD data from the GO Consortium
19. MGD IEA MGD IEA
20. G protein-coupled receptor kinase 6/beta-arrestin 2 system in a rat model of dopamine supersensitivity psychosis. Oda Y, etal., J Psychopharmacol. 2015 Dec;29(12):1308-13. doi: 10.1177/0269881115593903. Epub 2015 Jul 14.
21. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
22. β-Arrestin2 influences the response to methadone in opioid-dependent patients. Oneda B, etal., Pharmacogenomics J. 2011 Aug;11(4):258-66. doi: 10.1038/tpj.2010.37. Epub 2010 Jun 1.
23. Beta-arrestin- and G protein receptor kinase-mediated calcium-sensing receptor desensitization. Pi M, etal., Mol Endocrinol. 2005 Apr;19(4):1078-87. Epub 2005 Jan 6.
24. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
25. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
26. Mouse MP Annotation Import Pipeline RGD automated import pipeline
27. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
28. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
29. Licochalcone B Ameliorates Liver Cancer via Targeting of Apoptotic Genes, DNA Repair Systems, and Cell Cycle Control. Sadek K, etal., Iran J Pharm Res. 2020 Fall;19(4):372-386. doi: 10.22037/ijpr.2020.1101292.
30. Angiotensin II-stimulated signaling through G proteins and beta-arrestin. Shenoy SK and Lefkowitz RJ, Sci STKE. 2005 Nov 22;2005(311):cm14.
31. Beta-arrestins 1 and 2 are associated with nicotine dependence in European American smokers. Sun D, etal., Mol Psychiatry. 2008 Apr;13(4):398-406. doi: 10.1038/sj.mp.4002036. Epub 2007 Jun 19.
32. Arrb2 causes hepatic lipid metabolism disorder via AMPK pathway based on metabolomics in alcoholic fatty liver. Sun YY, etal.
33. Biased agonism of the calcium-sensing receptor. Thomsen AR, etal., Cell Calcium. 2012 Feb;51(2):107-16. doi: 10.1016/j.ceca.2011.11.009. Epub 2011 Dec 20.
34. Molecular basis of parathyroid hormone receptor signaling and trafficking: a family B GPCR paradigm. Vilardaga JP, etal., Cell Mol Life Sci. 2011 Jan;68(1):1-13. doi: 10.1007/s00018-010-0465-9. Epub 2010 Aug 12.
35. β-arrestin2 functions as a key regulator in the sympathetic-triggered immunodepression after stroke. Wang H, etal., J Neuroinflammation. 2018 Apr 10;15(1):102. doi: 10.1186/s12974-018-1142-4.
36. The expression change of beta-arrestins in fibroblast-like synoviocytes from rats with collagen-induced arthritis and the effect of total glucosides of paeony. Wang QT, etal., J Ethnopharmacol. 2011 Jan 27;133(2):511-6. Epub 2010 Oct 19.
37. Overactivation of cannabinoid receptor type 1 in rostral ventrolateral medulla promotes cardiovascular responses in spontaneously hypertensive rats. Wang T, etal., J Hypertens. 2017 Mar;35(3):538-545. doi: 10.1097/HJH.0000000000001179.
38. ß-Arrestin-biased AT1R stimulation promotes extracellular matrix synthesis in renal fibrosis. Wang Y, etal., Am J Physiol Renal Physiol. 2017 Jul 1;313(1):F1-F8. doi: 10.1152/ajprenal.00588.2016. Epub 2017 Mar 8.
39. ß-arrestin 2 mediates cardiac ischemia-reperfusion injury via inhibiting GPCR-independent cell survival signalling. Wang Y, etal., Cardiovasc Res. 2017 Nov 1;113(13):1615-1626. doi: 10.1093/cvr/cvx147.
40. The contribution of rare and common variants in 30 genes to risk nicotine dependence. Yang J, etal., Mol Psychiatry. 2015 Nov;20(11):1467-78. doi: 10.1038/mp.2014.156. Epub 2014 Dec 2.
41. Reduced expression of arrestin beta 2 by graft monocytes during acute rejection of rat kidneys. Zakrzewicz A, etal., Immunobiology. 2011 Jul;216(7):854-61. doi: 10.1016/j.imbio.2010.11.005. Epub 2010 Dec 3.
42. Role of ssarrestins in bradykinin B2 receptor-mediated signalling. Zimmerman B, etal., Cell Signal. 2011 Apr;23(4):648-59. doi: 10.1016/j.cellsig.2010.11.016. Epub 2010 Dec 8.
Additional References at PubMed
PMID:1458825   PMID:7613043   PMID:7932878   PMID:8889548   PMID:9333241   PMID:10349636   PMID:10508404   PMID:10549660   PMID:10617462   PMID:11042159   PMID:11076861   PMID:11130073  
PMID:11171997   PMID:11217851   PMID:11588219   PMID:12167659   PMID:12393857   PMID:12451149   PMID:12477932   PMID:12925697   PMID:12944399   PMID:12947104   PMID:12958365   PMID:14610273  
PMID:14614085   PMID:14744875   PMID:15218143   PMID:15364949   PMID:15489334   PMID:15705780   PMID:15718284   PMID:15765183   PMID:15782199   PMID:15788776   PMID:16027114   PMID:16051150  
PMID:16141072   PMID:16141073   PMID:16210646   PMID:16263766   PMID:16319069   PMID:16325578   PMID:16378096   PMID:16809338   PMID:16980301   PMID:17060617   PMID:17060906   PMID:17418896  
PMID:17426148   PMID:17442737   PMID:17494695   PMID:17525124   PMID:17540773   PMID:17594911   PMID:17618287   PMID:17680774   PMID:18180038   PMID:18191226   PMID:18194271   PMID:18195357  
PMID:18367649   PMID:18390755   PMID:18497258   PMID:18519945   PMID:18604210   PMID:18612077   PMID:18622177   PMID:18691971   PMID:18775329   PMID:18802075   PMID:18952848   PMID:19008961  
PMID:19047375   PMID:19113915   PMID:19122674   PMID:19126537   PMID:19129399   PMID:19224602   PMID:19279269   PMID:19309759   PMID:19349687   PMID:19429870   PMID:19477151   PMID:19477204  
PMID:19560570   PMID:19783052   PMID:19794961   PMID:19805483   PMID:19896992   PMID:19955404   PMID:20060823   PMID:20207744   PMID:20368153   PMID:20421423   PMID:20460106   PMID:20465566  
PMID:20497256   PMID:20530803   PMID:20589830   PMID:20713067   PMID:20813258   PMID:20886089   PMID:20926677   PMID:20980993   PMID:21106537   PMID:21139074   PMID:21183229   PMID:21228603  
PMID:21267068   PMID:21321125   PMID:21369867   PMID:21389118   PMID:21411739   PMID:21543334   PMID:21630325   PMID:21677750   PMID:21700709   PMID:21757712   PMID:21821916   PMID:21824517  
PMID:21855149   PMID:21857681   PMID:21873635   PMID:21891823   PMID:22025682   PMID:22025698   PMID:22034973   PMID:22174878   PMID:22264443   PMID:22308427   PMID:22315403   PMID:22318609  
PMID:22491351   PMID:22523395   PMID:22581458   PMID:22688330   PMID:22689562   PMID:22699970   PMID:22773819   PMID:22886417   PMID:22888001   PMID:22952227   PMID:23012429   PMID:23166351  
PMID:23188793   PMID:23202293   PMID:23235155   PMID:23449980   PMID:23524589   PMID:23536892   PMID:23541635   PMID:23557604   PMID:23589623   PMID:23660189   PMID:23689346   PMID:23753627  
PMID:23775075   PMID:23809162   PMID:23839051   PMID:23859136   PMID:23861891   PMID:23960234   PMID:24056371   PMID:24094141   PMID:24194600   PMID:24317793   PMID:24577407   PMID:24597632  
PMID:24695785   PMID:24817116   PMID:24911523   PMID:24947582   PMID:24974728   PMID:25012660   PMID:25083714   PMID:25104498   PMID:25147978   PMID:25194025   PMID:25196998   PMID:25318610  
PMID:25354317   PMID:25569510   PMID:25658948   PMID:25800153   PMID:25831532   PMID:25918399   PMID:25964346   PMID:26012717   PMID:26056051   PMID:26077142   PMID:26103985   PMID:26138465  
PMID:26157145   PMID:26169958   PMID:26240334   PMID:26244553   PMID:26296063   PMID:26318102   PMID:26362717   PMID:26371162   PMID:26459714   PMID:26496610   PMID:26503786   PMID:26582201  
PMID:26663782   PMID:26702092   PMID:26703465   PMID:26839314   PMID:27013682   PMID:27054338   PMID:27128598   PMID:27152166   PMID:27452469   PMID:27538456   PMID:27626380   PMID:27664421  
PMID:27759077   PMID:27815373   PMID:27886171   PMID:27911784   PMID:27911814   PMID:27974210   PMID:28145434   PMID:28181498   PMID:28329674   PMID:28419873   PMID:28650340   PMID:28855588  
PMID:28912160   PMID:28941296   PMID:28973019   PMID:29073113   PMID:29133163   PMID:29166587   PMID:29263312   PMID:29317519   PMID:29361236   PMID:29375207   PMID:29483145   PMID:29515120  
PMID:29627294   PMID:29669290   PMID:29713080   PMID:29727618   PMID:29786071   PMID:30087177   PMID:30196744   PMID:30333137   PMID:30335499   PMID:30401786   PMID:30485815   PMID:30541881  
PMID:30556810   PMID:30576947   PMID:30586762   PMID:30718498   PMID:30721232   PMID:30726732   PMID:30793522   PMID:30923807   PMID:31077686   PMID:31088898   PMID:31108170   PMID:31163126  
PMID:31270323   PMID:31469177   PMID:31612867   PMID:31622341   PMID:31780259   PMID:32035036   PMID:32052419   PMID:32071246   PMID:32071304   PMID:32165725   PMID:32325033   PMID:32403971  
PMID:32404425   PMID:32413335   PMID:32470395   PMID:32471718   PMID:32537493   PMID:32855529   PMID:32978390   PMID:33116250   PMID:33243993   PMID:33367479   PMID:33378226   PMID:33526871  
PMID:33668926   PMID:33710266   PMID:33811988   PMID:34031190   PMID:34344831   PMID:34480046   PMID:34512376   PMID:34570983   PMID:34710848   PMID:34873237   PMID:34879231   PMID:35008921  
PMID:35398487   PMID:35449600   PMID:35472681   PMID:35644498   PMID:36183107   PMID:36215165   PMID:36384129   PMID:36399825   PMID:36744494   PMID:36796753   PMID:36976866   PMID:37046359  
PMID:37225848   PMID:37316665   PMID:37897727   PMID:38267365   PMID:38355793   PMID:38613153   PMID:38629290   PMID:38844905   PMID:38883814  


Genomics

Comparative Map Data
Arrb2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391170,323,051 - 70,331,654 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1170,323,461 - 70,331,654 (+)EnsemblGRCm39 Ensembl
GRCm381170,432,485 - 70,440,828 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1170,432,635 - 70,440,828 (+)EnsemblGRCm38mm10GRCm38
MGSCv371170,246,155 - 70,254,176 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361170,248,893 - 70,257,018 (+)NCBIMGSCv36mm8
Celera1177,978,619 - 77,986,640 (+)NCBICelera
Cytogenetic Map11B3NCBI
cM Map1142.99NCBI
ARRB2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38174,710,632 - 4,721,497 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl174,710,596 - 4,721,499 (+)EnsemblGRCh38hg38GRCh38
GRCh37174,613,927 - 4,624,792 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,560,538 - 4,571,544 (+)NCBINCBI36Build 36hg18NCBI36
Build 34174,560,537 - 4,571,543NCBI
Celera174,629,166 - 4,639,975 (+)NCBICelera
Cytogenetic Map17p13.2NCBI
HuRef174,502,952 - 4,513,866 (+)NCBIHuRef
CHM1_1174,622,557 - 4,633,518 (+)NCBICHM1_1
T2T-CHM13v2.0174,600,371 - 4,611,146 (+)NCBIT2T-CHM13v2.0
Arrb2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81055,645,539 - 55,653,485 (+)NCBIGRCr8
mRatBN7.21055,146,887 - 55,154,854 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1055,146,818 - 55,154,850 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1059,825,196 - 59,833,080 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01059,313,709 - 59,321,593 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01054,812,911 - 54,820,795 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01057,040,252 - 57,048,045 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1057,040,267 - 57,048,134 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01056,797,489 - 56,805,282 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41057,244,071 - 57,284,166 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11057,289,995 - 57,297,789 (+)NCBI
Celera1054,285,120 - 54,301,063 (+)NCBICelera
Cytogenetic Map10q24NCBI
Arrb2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546710,110,003 - 10,123,022 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495546710,109,985 - 10,118,687 (+)NCBIChiLan1.0ChiLan1.0
ARRB2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21912,328,333 - 12,339,069 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11714,296,695 - 14,307,332 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0174,766,616 - 4,777,253 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1174,757,048 - 4,767,517 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl174,757,048 - 4,767,517 (+)Ensemblpanpan1.1panPan2
ARRB2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1531,831,208 - 31,838,875 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl531,829,864 - 31,839,454 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha531,968,270 - 31,977,918 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0531,934,052 - 31,943,706 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl531,934,872 - 31,943,667 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1531,900,361 - 31,910,009 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0531,860,046 - 31,869,691 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0532,036,284 - 32,045,935 (-)NCBIUU_Cfam_GSD_1.0
Arrb2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560252,719,545 - 52,727,921 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366773,172,925 - 3,181,520 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366773,173,054 - 3,181,475 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARRB2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1252,161,778 - 52,170,342 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11252,161,776 - 52,170,362 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21254,280,938 - 54,286,249 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ARRB2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1164,191,040 - 4,202,382 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl164,191,172 - 4,202,385 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605917,439,881 - 17,451,765 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arrb2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247868,568,198 - 8,577,914 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247868,568,102 - 8,576,445 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:3289
Count of miRNA genes:784
Interacting mature miRNAs:1030
Transcripts:ENSMUST00000079056, ENSMUST00000084954, ENSMUST00000102563, ENSMUST00000102564, ENSMUST00000108568, ENSMUST00000124112, ENSMUST00000124943, ENSMUST00000125441, ENSMUST00000128748, ENSMUST00000138006, ENSMUST00000143232, ENSMUST00000144454, ENSMUST00000150076
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
4141875Etax9_methanol induced ataxia 9 (mouse)Not determined5528498572209927Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114618516780185262Mouse
1301788Lbw8_mlupus NZB x NZW 8 (mouse)Not determined113650328770509492Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114516587379978324Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
1301896Tria1_mT-cell receptor induced activation 1 (mouse)Not determined113661356570613855Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5871926685066529Mouse
4141853Skmw17_mskeletal muscle weight 17 (mouse)Not determined113708094171081064Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114570858189818733Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
13208559Wght10_mweight 10 (mouse)11395000088890826Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115249438586494385Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
36049792Ars5_mantibody response to SARS-CoV 5, day 7, IgM (mouse)116899082672490826Mouse
13208558Lgth12_mbody length 12 (mouse)11395000094890826Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115775466091754758Mouse
10053682Eae45_mexperimental allergic encephalomyelitis susceptibility 45 (mouse)Not determined115849055574754758Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15850803087695238Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113589082784890826Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
11532699Sluc36b_msusceptibility to lung cancer 36b (mouse)114225661776256730Mouse
11532698Sluc36a_msusceptibility to lung cancer 36a (mouse)114225661776256730Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115339058887390737Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115412675283733652Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11688027789019734Mouse
35673314Ari2_mantibody response to influenza 2, day 10, IgG3 (mouse)116899082672490826Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113628257783481356Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112180736495881231Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116707819179813912Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116215600596156153Mouse
36049778Ars6_mantibody response to SARS-CoV 6, day 15, IgM (mouse)116899082672490826Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115007819184078411Mouse
36049779Ars7_mantibody response to SARS-CoV 7, day 29, IgG1 (mouse)116899082672490826Mouse
36049790Ars3_mantibody response to SARS-CoV 3, day 7, IgG2b (mouse)116899082672490826Mouse
36049791Ars4_mantibody response to SARS-CoV 4, day 7, IgG3 (mouse)116899082672490826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
36049788Ars1_mantibody response to SARS-CoV 1, day 7, IgG1 (mouse)116899082672490826Mouse
36049789Ars2_mantibody response to SARS-CoV 2, day 7, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049786Ars10_mantibody response to SARS-CoV 10, 4 days post-rechallenge, IgG2a+IgG2c (mouse)116899082672490826Mouse
10766457Nwa3_mNew Zealand White autoimmunity 3 (mouse)113801611572016209Mouse
36049787Ars11_mantibody response to SARS-CoV 11, 4 days post-rechallenge, IgM (mouse)116899082672490826Mouse
36049784Ars8_mantibody response to SARS-CoV 8, day 29, IgG2a+IgG2c (mouse)116899082672490826Mouse
36049785Ars9_mantibody response to SARS-CoV 9, day 29, IgM (mouse)116899082672490826Mouse
4142300Ctrq3_mC. trachomatis resistance QTL 3 (mouse)Not determined114463003876854757Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116168682088699728Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114631940780319522Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1912420496897826Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116331940781830473Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116331940794063918Mouse
26884453Sklq16_mskull length QTL 16, 16 week (mouse)11325000072690826Mouse

Markers in Region
AI326910  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381170,440,521 - 70,440,613UniSTSGRCm38
MGSCv371170,254,023 - 70,254,115UniSTSGRCm37
Celera1177,986,487 - 77,986,579UniSTS
Cytogenetic Map11B3UniSTS
cM Map1145.0UniSTS
Whitehead/MRC_RH11906.87UniSTS
Whitehead/MRC_RH11906.67UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001271358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271359 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001271360 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_145429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036156574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003949383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003949384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK089542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170647 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY201367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR936841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000079056   ⟹   ENSMUSP00000078065
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,471 - 70,331,654 (+)Ensembl
GRCm38.p6 Ensembl1170,432,645 - 70,440,828 (+)Ensembl
Ensembl Acc Id: ENSMUST00000084954   ⟹   ENSMUSP00000082018
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,463 - 70,331,500 (+)Ensembl
GRCm38.p6 Ensembl1170,432,637 - 70,440,674 (+)Ensembl
Ensembl Acc Id: ENSMUST00000102563   ⟹   ENSMUSP00000099623
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,524 - 70,331,649 (+)Ensembl
GRCm38.p6 Ensembl1170,432,698 - 70,440,823 (+)Ensembl
Ensembl Acc Id: ENSMUST00000102564   ⟹   ENSMUSP00000099624
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,479 - 70,331,620 (+)Ensembl
GRCm38.p6 Ensembl1170,432,653 - 70,440,794 (+)Ensembl
Ensembl Acc Id: ENSMUST00000108568   ⟹   ENSMUSP00000104208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,463 - 70,331,500 (+)Ensembl
GRCm38.p6 Ensembl1170,432,637 - 70,440,674 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124112
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,461 - 70,326,822 (+)Ensembl
GRCm38.p6 Ensembl1170,432,635 - 70,435,996 (+)Ensembl
Ensembl Acc Id: ENSMUST00000124943   ⟹   ENSMUSP00000136978
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,503 - 70,328,431 (+)Ensembl
GRCm38.p6 Ensembl1170,432,677 - 70,437,605 (+)Ensembl
Ensembl Acc Id: ENSMUST00000125441
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,327,729 - 70,329,548 (+)Ensembl
GRCm38.p6 Ensembl1170,436,903 - 70,438,722 (+)Ensembl
Ensembl Acc Id: ENSMUST00000128748   ⟹   ENSMUSP00000134349
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,508 - 70,329,573 (+)Ensembl
GRCm38.p6 Ensembl1170,432,682 - 70,438,747 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138006
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,327,525 - 70,331,059 (+)Ensembl
GRCm38.p6 Ensembl1170,436,699 - 70,440,233 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143232
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,328,118 - 70,330,379 (+)Ensembl
GRCm38.p6 Ensembl1170,437,292 - 70,439,553 (+)Ensembl
Ensembl Acc Id: ENSMUST00000144454
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,329,408 - 70,331,054 (+)Ensembl
GRCm38.p6 Ensembl1170,438,582 - 70,440,228 (+)Ensembl
Ensembl Acc Id: ENSMUST00000150076   ⟹   ENSMUSP00000136601
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1170,323,508 - 70,327,578 (+)Ensembl
GRCm38.p6 Ensembl1170,432,682 - 70,436,752 (+)Ensembl
RefSeq Acc Id: NM_001271358   ⟹   NP_001258287
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,406 - 70,331,654 (+)NCBI
GRCm381170,432,580 - 70,440,828 (+)NCBI
Celera1177,978,546 - 77,986,794 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271359   ⟹   NP_001258288
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,406 - 70,331,654 (+)NCBI
GRCm381170,432,580 - 70,440,828 (+)NCBI
Celera1177,978,546 - 77,986,794 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001271360   ⟹   NP_001258289
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,406 - 70,331,654 (+)NCBI
GRCm381170,432,580 - 70,440,828 (+)NCBI
Celera1177,978,546 - 77,986,794 (+)NCBI
Sequence:
RefSeq Acc Id: NM_145429   ⟹   NP_663404
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,406 - 70,331,654 (+)NCBI
GRCm381170,432,580 - 70,440,828 (+)NCBI
MGSCv371170,246,155 - 70,254,176 (+)RGD
Celera1177,978,546 - 77,986,794 (+)NCBI
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036156573   ⟹   XP_036012466
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,479 - 70,331,649 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036156574   ⟹   XP_036012467
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,474 - 70,331,649 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003949383
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,051 - 70,331,649 (+)NCBI
GRCm381170,432,485 - 70,440,823 (+)NCBI
Sequence:
RefSeq Acc Id: XR_003949384
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391170,323,051 - 70,331,649 (+)NCBI
GRCm381170,432,485 - 70,440,823 (+)NCBI
Sequence:
RefSeq Acc Id: NP_663404   ⟸   NM_145429
- Peptide Label: isoform b
- UniProtKB: Q91YI4 (UniProtKB/Swiss-Prot),   Q5F2E0 (UniProtKB/Swiss-Prot),   Q5F2D8 (UniProtKB/Swiss-Prot),   Q3TCM2 (UniProtKB/Swiss-Prot),   A0A158SIT9 (UniProtKB/TrEMBL),   Q3TRC8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258287   ⟸   NM_001271358
- Peptide Label: isoform a
- UniProtKB: J3JS97 (UniProtKB/TrEMBL),   Q5F2D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258288   ⟸   NM_001271359
- Peptide Label: isoform a
- UniProtKB: J3JS97 (UniProtKB/TrEMBL),   Q5F2D9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001258289   ⟸   NM_001271360
- Peptide Label: isoform b
- UniProtKB: Q91YI4 (UniProtKB/Swiss-Prot),   Q5F2E0 (UniProtKB/Swiss-Prot),   Q5F2D8 (UniProtKB/Swiss-Prot),   Q3TCM2 (UniProtKB/Swiss-Prot),   A0A158SIT9 (UniProtKB/TrEMBL),   Q3TRC8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000136601   ⟸   ENSMUST00000150076
Ensembl Acc Id: ENSMUSP00000136978   ⟸   ENSMUST00000124943
Ensembl Acc Id: ENSMUSP00000082018   ⟸   ENSMUST00000084954
Ensembl Acc Id: ENSMUSP00000078065   ⟸   ENSMUST00000079056
Ensembl Acc Id: ENSMUSP00000104208   ⟸   ENSMUST00000108568
Ensembl Acc Id: ENSMUSP00000134349   ⟸   ENSMUST00000128748
Ensembl Acc Id: ENSMUSP00000099624   ⟸   ENSMUST00000102564
Ensembl Acc Id: ENSMUSP00000099623   ⟸   ENSMUST00000102563
RefSeq Acc Id: XP_036012467   ⟸   XM_036156574
- Peptide Label: isoform X2
RefSeq Acc Id: XP_036012466   ⟸   XM_036156573
- Peptide Label: isoform X1
- UniProtKB: Q5F2D9 (UniProtKB/TrEMBL)
Protein Domains
Arrestin C-terminal-like   Arrestin-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q91YI4-F1-model_v2 AlphaFold Q91YI4 1-410 view protein structure

Promoters
RGD ID:6820422
Promoter ID:MM_KWN:8208
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   Spleen
Transcripts:ENSMUST00000079056,   OTTMUST00000013621,   OTTMUST00000013622,   OTTMUST00000013623,   OTTMUST00000013624,   OTTMUST00000013625,   OTTMUST00000013626,   OTTMUST00000040715,   UC007JUU.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,245,849 - 70,246,349 (+)MPROMDB
RGD ID:6849019
Promoter ID:MM_XEF:1135
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:NM_001092112,   NM_001093097,   NM_001100251,   NM_001171899,   NM_001172094,   NM_201124,   NM_214681
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,248,786 - 70,249,286 (+)MPROMDB
RGD ID:6820421
Promoter ID:MM_KWN:8209
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:OTTMUST00000013616,   OTTMUST00000013617,   OTTMUST00000013627
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,249,836 - 70,250,687 (+)MPROMDB
RGD ID:6820417
Promoter ID:MM_KWN:8210
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour
Transcripts:OTTMUST00000013618
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361170,251,486 - 70,251,986 (+)MPROMDB
RGD ID:8675314
Promoter ID:EPDNEW_M15688
Type:initiation region
Name:Arrb2_1
Description:Mus musculus arrestin, beta 2 , transcript variant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381170,432,664 - 70,432,724EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99474 AgrOrtholog
Ensembl Genes ENSMUSG00000060216 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000079056 ENTREZGENE
  ENSMUST00000079056.9 UniProtKB/Swiss-Prot
  ENSMUST00000084954.13 UniProtKB/TrEMBL
  ENSMUST00000102563 ENTREZGENE
  ENSMUST00000102563.2 UniProtKB/Swiss-Prot
  ENSMUST00000102564 ENTREZGENE
  ENSMUST00000102564.11 UniProtKB/Swiss-Prot
  ENSMUST00000108568 ENTREZGENE
  ENSMUST00000108568.10 UniProtKB/Swiss-Prot
  ENSMUST00000124943.8 UniProtKB/TrEMBL
  ENSMUST00000128748.8 UniProtKB/TrEMBL
  ENSMUST00000150076.8 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.640 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  2.60.40.840 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Arrestin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin-like_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_C-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_E-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:216869 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:99474 ENTREZGENE
NCBI Gene Arrb2 ENTREZGENE
PANTHER BETA-ARRESTIN-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11792 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Arrestin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Arrb2 PhenoGen
PRINTS ARRESTIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ARRESTINS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Arrestin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF81296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A158SIT9 ENTREZGENE, UniProtKB/TrEMBL
  ARRB2_MOUSE UniProtKB/Swiss-Prot
  G3UZ54_MOUSE UniProtKB/TrEMBL
  J3JS97 ENTREZGENE, UniProtKB/TrEMBL
  J3QN53_MOUSE UniProtKB/TrEMBL
  J3QNV6_MOUSE UniProtKB/TrEMBL
  Q3TCM2 ENTREZGENE
  Q3TRC8 ENTREZGENE, UniProtKB/TrEMBL
  Q3UCU5_MOUSE UniProtKB/TrEMBL
  Q5F2D8 ENTREZGENE
  Q5F2D9 ENTREZGENE, UniProtKB/TrEMBL
  Q5F2E0 ENTREZGENE
  Q91YI4 ENTREZGENE
UniProt Secondary Q3TCM2 UniProtKB/Swiss-Prot
  Q5F2D8 UniProtKB/Swiss-Prot
  Q5F2E0 UniProtKB/Swiss-Prot