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Gene: Arrb1 (arrestin, beta 1) Mus musculus
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Symbol: Arrb1
Name: arrestin, beta 1
Description: Exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process and mitogen-activated protein kinase kinase binding activity. Involved in several processes, including positive regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of cellular protein metabolic process; and regulation of signal transduction. Localizes to the cytosol and pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human ARRB1 (arrestin beta 1); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; corticotropin-releasing hormone signaling pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-butoxyethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200006I17Rik; arrestin beta-1; arrestin, beta 1, isoform B; AW208571; beta-arrestin-1; beta-arrestin1; G430100A01Rik; MGC124269; MGC124270
Orthologs:
Homo sapiens (human) : ARRB1 (arrestin beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arrb1 (arrestin, beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrb1 (arrestin beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRB1 (arrestin beta 1)
Canis lupus familiaris (dog) : ARRB1 (arrestin beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrb1 (arrestin beta 1)
Sus scrofa (pig) : ARRB1 (arrestin beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38799,535,147 - 99,606,772 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377106,683,996 - 106,755,281 (+)NCBIGRCm37mm9NCBIm37
MGSCv36799,409,569 - 99,480,854 (+)NCBImm8
Celera799,859,615 - 99,932,041 (+)NCBICelera
Cytogenetic Map7 E1NCBI
cM Map754.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Arrb1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10191
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.