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Gene: Arrb1 (arrestin, beta 1) Mus musculus
Symbol: Arrb1
Name: arrestin, beta 1
RGD ID: 10191
Description: Exhibits cysteine-type endopeptidase inhibitor activity involved in apoptotic process and mitogen-activated protein kinase kinase binding activity. Involved in several processes, including positive regulation of insulin secretion involved in cellular response to glucose stimulus; regulation of cellular protein metabolic process; and regulation of signal transduction. Localizes to cytosol and pseudopodium. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver; and respiratory system. Orthologous to human ARRB1 (arrestin beta 1); PARTICIPATES IN angiotensin II signaling pathway via AT1 receptor; calcium signaling pathway via the calcium-sensing receptor; corticotropin-releasing hormone signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1200006I17Rik; arrestin beta-1; arrestin, beta 1, isoform B; AW208571; beta-arrestin-1; beta-arrestin1; G430100A01Rik; MGC124269; MGC124270
Homo sapiens (human) : ARRB1 (arrestin beta 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Arrb1 (arrestin, beta 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Arrb1 (arrestin beta 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ARRB1 (arrestin beta 1)
Canis lupus familiaris (dog) : ARRB1 (arrestin beta 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Arrb1 (arrestin beta 1)
Sus scrofa (pig) : ARRB1 (arrestin beta 1)
Chlorocebus sabaeus (African green monkey) : ARRB1 (arrestin beta 1)
Heterocephalus glaber (naked mole-rat) : Arrb1 (arrestin beta 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39799,184,356 - 99,255,979 (+)NCBI
GRCm38799,535,147 - 99,606,772 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl799,535,466 - 99,606,771 (+)EnsemblGRCm38mm10GRCm38
MGSCv377106,683,996 - 106,755,281 (+)NCBIGRCm37mm9NCBIm37
MGSCv36799,409,569 - 99,480,854 (+)NCBImm8
Celera799,859,615 - 99,932,041 (+)NCBICelera
Cytogenetic Map7E1NCBI
cM Map754.09NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Arrb1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10191
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.