RGD Reference Report - Beta-arrestins: multifunctional cellular mediators. - Rat Genome Database

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Beta-arrestins: multifunctional cellular mediators.

Authors: Barki-Harrington, L  Rockman, HA 
Citation: Barki-Harrington L and Rockman HA, Physiology (Bethesda). 2008 Feb;23:17-22.
RGD ID: 4140419
Pubmed: PMID:18268361   (View Abstract at PubMed)
DOI: DOI:10.1152/physiol.00042.2007   (Journal Full-text)

Initially thought to play a role only in G-protein-coupled receptor desensitization, beta-arrestins are ascribed with new roles such as scaffolding and signaling proteins by their own right. This review explores the many functions of beta-arrestins, with an emphasis on their recently identified role as regulators of receptor signaling.

Molecular Pathway Annotations    Click to see Annotation Detail View

RGD Manual Annotations

Objects Annotated

Genes (Rattus norvegicus)
Arrb1  (arrestin, beta 1)
Arrb2  (arrestin, beta 2)

Genes (Mus musculus)
Arrb1  (arrestin, beta 1)
Arrb2  (arrestin, beta 2)

Genes (Homo sapiens)
ARRB1  (arrestin beta 1)
ARRB2  (arrestin beta 2)


Additional Information