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Gene: KLF7 (Kruppel like factor 7) Homo sapiens
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Symbol: KLF7
Name: Kruppel like factor 7
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including negative regulation of adipose tissue development; negative regulation of insulin secretion involved in cellular response to glucose stimulus; and regulation of transcription by RNA polymerase II. Localizes to nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Krueppel-like factor 7; Kruppel-like factor 7 (ubiquitous); ubiquitous krueppel-like factor; ubiquitous Kruppel-like factor; ubiquitous Kruppel-like transcription factor; UKLF
Orthologs:
Mus musculus (house mouse) : Klf7 (Kruppel-like factor 7 (ubiquitous))  MGI  Alliance
Rattus norvegicus (Norway rat) : Klf7 (Kruppel like factor 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Klf7 (Kruppel like factor 7)
Pan paniscus (bonobo/pygmy chimpanzee) : KLF7 (Kruppel like factor 7)
Canis lupus familiaris (dog) : KLF7 (Kruppel like factor 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Klf7 (Kruppel like factor 7)
Sus scrofa (pig) : KLF7 (Kruppel like factor 7)
Chlorocebus sabaeus (African green monkey) : KLF7 (Kruppel like factor 7)
Heterocephalus glaber (naked mole-rat) : Klf7 (Kruppel like factor 7)
more info ...
Related Pseudogenes: KLF7P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl2207,074,137 - 207,167,267 (-)EnsemblGRCh38hg38GRCh38
GRCh382207,074,137 - 207,173,851 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372207,938,861 - 208,031,970 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362207,653,774 - 207,738,859 (-)NCBINCBI36hg18NCBI36
Build 342207,771,034 - 207,856,120NCBI
Celera2201,706,987 - 201,792,085 (-)NCBI
Cytogenetic Map2q33.3NCBI
HuRef2199,788,743 - 199,882,048 (-)NCBIHuRef
CHM1_12207,944,767 - 208,037,841 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KLF7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314410
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.