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Gene: CCND2 (cyclin D2) Homo sapiens
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Symbol: CCND2
Name: cyclin D2
Description: Exhibits protein kinase binding activity. Involved in negative regulation of apoptotic process; positive regulation of cell cycle; and positive regulation of cell population proliferation. Localizes to several cellular components, including chromatin; cyclin-dependent protein kinase holoenzyme complex; and nucleus. Implicated in ductal carcinoma in situ; invasive lobular carcinoma; prostate cancer; and transitional cell carcinoma. Biomarker of germinoma; granulosa cell tumor; multiple myeloma; nephroblastoma; and seminoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: G1/S-specific cyclin D2; G1/S-specific cyclin-D2; KIAK0002; MGC102758; MPPH3
Orthologs:
Mus musculus (house mouse) : Ccnd2 (cyclin D2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ccnd2 (cyclin D2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccnd2 (cyclin D2)
Pan paniscus (bonobo/pygmy chimpanzee) : CCND2 (cyclin D2)
Canis lupus familiaris (dog) : CCND2 (cyclin D2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccnd2 (cyclin D2)
Sus scrofa (pig) : CCND2 (cyclin D2)
Chlorocebus sabaeus (African green monkey) : CCND2 (cyclin D2)
Heterocephalus glaber (naked mole-rat) : Ccnd2 (cyclin D2)
more info ...
Related Pseudogenes: CCND2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl124,273,762 - 4,305,353 (+)EnsemblGRCh38hg38GRCh38
GRCh38124,273,762 - 4,305,353 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37124,382,901 - 4,414,522 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,253,199 - 4,284,777 (+)NCBINCBI36hg18NCBI36
Build 34124,253,198 - 4,284,777NCBI
Celera126,004,961 - 6,036,590 (+)NCBI
Cytogenetic Map12p13.32NCBI
HuRef124,239,192 - 4,271,184 (+)NCBIHuRef
CHM1_1124,382,561 - 4,414,148 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
 
More on CCND2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730903
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.