(+)-alpha-tocopherol multiple interactions ISO RGD:10118 6480464 alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein], alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 (+)-catechin multiple interactions EXP 6480464 [Quercetin co-treated with Catechin] inhibits the reaction [AGT protein affects the localization of NCF1 protein] CTD PMID:22295890 (+)-taxifolin decreases expression ISO RGD:10118 6480464 taxifolin results in decreased expression of AGT protein modified form CTD PMID:24269735 (R)-lipoic acid multiple interactions ISO RGD:10118 6480464 [Thioctic Acid co-treated with Dietary Fats] results in decreased expression of AGT mRNA CTD PMID:27260466 (R)-mevalonic acid multiple interactions ISO RGD:2069 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]] CTD PMID:22306966 (R)-noradrenaline increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Norepinephrine CTD PMID:15741261 (R)-noradrenaline affects abundance ISO RGD:2069 6480464 Norepinephrine affects the abundance of AGT protein CTD PMID:614752 (R)-noradrenaline multiple interactions ISO RGD:2069 6480464 carvedilol inhibits the reaction [AGT protein results in increased abundance of Norepinephrine], Losartan inhibits the reaction [AGT protein results in increased abundance of Norepinephrine] CTD PMID:15741261 (S)-amphetamine affects expression ISO RGD:10118 6480464 Dextroamphetamine affects the expression of AGT mRNA CTD PMID:12558987 1-(5-isoquinolinesulfonyl)-2-methylpiperazine multiple interactions ISO RGD:2069 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA], 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 11-deoxycorticosterone increases activity ISO RGD:2069 6480464 Desoxycorticosterone results in increased activity of AGT protein CTD PMID:9087624 13-BETA-ETHYL-17-ALPHA-ETHYNYL-17-BETA-HYDROXYGON-4-EN-3-ONE multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of AGT protein CTD PMID:17519148 14,15-EET multiple interactions ISO RGD:10118 6480464 14 more ... CTD PMID:27428043 14,15-EET multiple interactions ISO RGD:2069 6480464 [14 more ... CTD PMID:27428043 14,15-EET decreases expression ISO RGD:2069 6480464 14 more ... CTD PMID:27428043 14,15-EET increases cleavage ISO RGD:2069 6480464 14 more ... CTD PMID:27428043 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO RGD:2069 6480464 15-deoxy-delta(12 more ... CTD PMID:18278065 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of AGT protein more ... CTD PMID:11095476 , PMID:17519148 17alpha-ethynylestradiol increases expression EXP 6480464 Ethinyl Estradiol results in increased expression of AGT protein CTD PMID:11095476 , PMID:17374706 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of AGT mRNA CTD PMID:25136773 17beta-estradiol increases expression ISO RGD:10118 6480464 Estradiol results in increased expression of AGT mRNA CTD PMID:19484750 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of AGT mRNA CTD PMID:14699072 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of AGT mRNA more ... CTD PMID:14699072 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10118 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGT mRNA CTD PMID:23864506 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGT mRNA CTD PMID:28011154 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10118 6480464 Tetrachlorodibenzodioxin affects the expression of AGT mRNA CTD PMID:26377647 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2069 6480464 Tetrachlorodibenzodioxin results in decreased expression of AGT mRNA CTD PMID:20959002 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:2069 6480464 AHR protein alternative form affects the reaction [Tetrachlorodibenzodioxin results in decreased expression of AGT mRNA] CTD PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10118 6480464 Tetrachlorodibenzodioxin promotes the reaction [AGT protein modified form results in increased expression of COL1A1 mRNA] CTD PMID:18670907 2,6-di-tert-butyl-4-methylphenol multiple interactions ISO RGD:10118 6480464 Butylated Hydroxytoluene inhibits the reaction [AGT protein results in increased expression of PSMC6 protein], Butylated Hydroxytoluene inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 2,6-dinitrotoluene affects expression ISO RGD:2069 6480464 2, 6-dinitrotoluene affects the expression of AGT mRNA CTD PMID:21346803 2-amino-2-deoxy-D-glucopyranose increases expression ISO RGD:10118 6480464 Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 3',5'-cyclic GMP multiple interactions ISO RGD:2069 6480464 AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP] more ... CTD PMID:11696475 , PMID:28299329 3',5'-cyclic GMP increases abundance ISO RGD:2069 6480464 AGT protein modified form results in increased abundance of Cyclic GMP CTD PMID:28299329 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine affects expression ISO RGD:2069 6480464 Puromycin Aminonucleoside affects the expression of AGT protein CTD PMID:8446257 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine decreases expression ISO RGD:2069 6480464 Puromycin Aminonucleoside results in decreased expression of AGT protein CTD PMID:2236972 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO RGD:2069 6480464 Puromycin Aminonucleoside results in increased expression of AGT mRNA CTD PMID:12495295 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO RGD:2069 6480464 [Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGT mRNA CTD PMID:12495295 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:10118 6480464 3 more ... CTD PMID:19467301 3,3',4,4'-tetrachlorobiphenyl increases expression ISO RGD:10118 6480464 3 more ... CTD PMID:21925196 3,4-methylenedioxymethamphetamine increases expression ISO RGD:10118 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of AGT mRNA CTD PMID:20188158 3,4-methylenedioxymethamphetamine increases methylation ISO RGD:10118 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in increased methylation of AGT promoter CTD PMID:26251327 3,4-methylenedioxymethamphetamine decreases expression ISO RGD:10118 6480464 N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of AGT mRNA CTD PMID:26251327 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide multiple interactions EXP 6480464 Clozapine promotes the reaction [Raclopride promotes the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]] more ... CTD PMID:11549694 3,7-dihydropurine-6-thione decreases expression ISO RGD:2069 6480464 Mercaptopurine results in decreased expression of AGT mRNA CTD PMID:23358152 3-[3-acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl]-1,1-diethylurea affects response to substance EXP 6480464 AGT protein polymorphism affects the susceptibility to Celiprolol CTD PMID:12911327 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO RGD:2069 6480464 bisindolylmaleimide I inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 mRNA] more ... CTD PMID:12409145 , PMID:18250367 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [AGT protein results in increased expression of KDR mRNA] CTD PMID:15005273 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:10118 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of AGT mRNA more ... CTD PMID:16054899 , PMID:28285642 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of AGT mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGT mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of AGT mRNA CTD PMID:27685785 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of AGT mRNA CTD PMID:28628672 4-hydroperoxycyclophosphamide decreases response to substance EXP 6480464 AGT protein results in decreased susceptibility to perfosfamide CTD PMID:11034089 4-hydroxynon-2-enal affects binding EXP 6480464 4-hydroxy-2-nonenal binds to AGT protein modified form, AGT protein modified form binds to 4-hydroxy-2-nonenal CTD PMID:20977208 , PMID:31144504 4-hydroxynon-2-enal multiple interactions EXP 6480464 4-hydroxy-2-nonenal binds to and results in increased lipidation of AGT protein modified form more ... CTD PMID:26111765 , PMID:31144504 4-methyl-N1-(3-phenylpropyl)benzene-1,2-diamine multiple interactions EXP 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1, 2-diamine inhibits the reaction [cyanidin 3-O-glucoside inhibits the reaction [AGT protein results in increased expression of NOS2 protein]] CTD PMID:27983965 4-phenylbutyric acid multiple interactions ISO RGD:2069 6480464 4-phenylbutyric acid inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein] more ... CTD PMID:25398788 5-(2-methylpiperazine-1-sulfonyl)isoquinoline multiple interactions ISO RGD:2069 6480464 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1A mRNA], 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine inhibits the reaction [AGT protein results in increased expression of ADRA1D mRNA] CTD PMID:7900855 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole affects expression ISO RGD:2069 6480464 Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 6-oxoprostaglandin F1alpha increases abundance ISO RGD:2069 6480464 AGT protein alternative form results in increased abundance of 6-Ketoprostaglandin F1 alpha CTD PMID:4030047 6-oxoprostaglandin F1alpha multiple interactions ISO RGD:2069 6480464 Dexamethasone inhibits the reaction [AGT protein alternative form results in increased abundance of 6-Ketoprostaglandin F1 alpha] CTD PMID:4030047 6-propyl-2-thiouracil affects expression ISO RGD:2069 6480464 Propylthiouracil affects the expression of AGT mRNA CTD PMID:19483382 6-propyl-2-thiouracil decreases expression ISO RGD:2069 6480464 Propylthiouracil results in decreased expression of AGT mRNA CTD PMID:24780913 more ... 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 resveratrol inhibits the reaction [Uric Acid results in increased expression of AGT mRNA], resveratrol inhibits the reaction [Uric Acid results in increased expression of AGT protein] CTD PMID:25493383 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression ISO RGD:10118 6480464 Uric Acid results in increased expression of AGT mRNA, Uric Acid results in increased expression of AGT protein modified form CTD PMID:30710622 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:10118 6480464 APLN protein modified form inhibits the reaction [Uric Acid results in increased expression of AGT mRNA], APLN protein modified form inhibits the reaction [Uric Acid results in increased expression of AGT protein modified form] CTD PMID:30710622 7,9-dihydro-1H-purine-2,6,8(3H)-trione increases expression EXP 6480464 Uric Acid results in increased expression of AGT mRNA, Uric Acid results in increased expression of AGT protein CTD PMID:25493383 8-bromo-3',5'-cyclic AMP decreases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of AGT mRNA CTD PMID:22079614 AACOCF3 multiple interactions ISO RGD:2069 6480464 arachidonyltrifluoromethane inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] CTD PMID:14613874 acetylcholine multiple interactions ISO RGD:10118 6480464 ATOX1 protein inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine] more ... CTD PMID:18768397 more ... acetylcholine decreases response to substance ISO RGD:10118 6480464 AGT protein modified form results in decreased susceptibility to Acetylcholine, AGT protein results in decreased susceptibility to Acetylcholine CTD PMID:18174886 more ... acetylsalicylic acid affects activity EXP 6480464 Aspirin affects the activity of AGT protein CTD PMID:3189434 actinomycin D multiple interactions EXP 6480464 Dactinomycin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA], Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA] CTD PMID:16705055 , PMID:17214612 actinomycin D multiple interactions ISO RGD:2069 6480464 Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA] more ... CTD PMID:19292980 , PMID:23288202 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of AGT protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:10118 6480464 Aflatoxin B1 results in decreased expression of AGT mRNA CTD PMID:19770486 aldehydo-D-glucosamine increases expression ISO RGD:10118 6480464 Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 aldehydo-D-glucose multiple interactions EXP 6480464 (3 more ... CTD PMID:15677497 more ... aldehydo-D-glucose increases expression ISO RGD:2069 6480464 Glucose results in increased expression of AGT mRNA, Glucose results in increased expression of AGT protein CTD PMID:12130563 , PMID:19861503 aldehydo-D-glucose affects metabolic processing ISO RGD:2069 6480464 AGT protein affects the metabolism of Glucose CTD PMID:11115780 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of AGT protein CTD PMID:16452552 aldehydo-D-glucose multiple interactions ISO RGD:2069 6480464 1 more ... CTD PMID:12130563 , PMID:19861503 aldosterone increases secretion ISO RGD:10118 6480464 AGT protein results in increased secretion of Aldosterone CTD PMID:20175999 aldosterone increases secretion EXP 6480464 AGT protein results in increased secretion of Aldosterone CTD PMID:11549694 more ... aldosterone multiple interactions ISO RGD:10118 6480464 AGT protein affects the reaction [SLC9A3 gene mutant form results in increased abundance of Aldosterone] CTD PMID:26564064 aldosterone increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Aldosterone, AGT protein results in increased abundance of Aldosterone CTD PMID:25617244 , PMID:26564064 aldosterone increases abundance ISO RGD:2069 6480464 AGT protein modified form results in increased abundance of Aldosterone, AGT protein results in increased abundance of Aldosterone CTD PMID:16788141 more ... aldosterone increases expression ISO RGD:2069 6480464 Aldosterone results in increased expression of AGT protein alternative form CTD PMID:18660453 aldosterone multiple interactions ISO RGD:2069 6480464 AGT protein affects the reaction [DAB2 protein results in increased secretion of Aldosterone], AGT protein alternative form promotes the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:17303656 , PMID:18660453 aldosterone multiple interactions EXP 6480464 [AGT co-treated with REN] results in increased abundance of Aldosterone more ... CTD PMID:11549694 more ... aldosterone increases abundance EXP 6480464 AGT protein modified form results in increased abundance of Aldosterone, AGT protein results in increased abundance of Aldosterone CTD PMID:18331727 more ... aliskiren multiple interactions ISO RGD:2069 6480464 aliskiren inhibits the reaction [Indomethacin results in increased expression of AGT protein] CTD PMID:27645307 aliskiren multiple interactions ISO RGD:10118 6480464 aliskiren inhibits the reaction [microcystin RR results in increased expression of AGT protein] CTD PMID:28330766 aliskiren decreases expression ISO RGD:2069 6480464 aliskiren results in decreased expression of AGT protein modified form CTD PMID:18829990 all-trans-retinoic acid multiple interactions ISO RGD:10118 6480464 AGN 193109 inhibits the reaction [Tretinoin results in increased expression of AGT mRNA] CTD PMID:16505366 all-trans-retinoic acid multiple interactions ISO RGD:2069 6480464 Tretinoin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein], Tretinoin inhibits the reaction [AGT protein results in increased secretion of COL3A1 protein] CTD PMID:16539842 all-trans-retinoic acid increases expression ISO RGD:10118 6480464 Tretinoin results in increased expression of AGT mRNA CTD PMID:16505366 allopurinol multiple interactions ISO RGD:2069 6480464 Allopurinol inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species], Allopurinol inhibits the reaction [AGT protein results in increased expression of PTGS2 protein] CTD PMID:17244722 , PMID:19145780 alpha-cyano-4-hydroxycinnamic acid multiple interactions ISO RGD:2069 6480464 alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT mRNA], alpha-cyano-4-hydroxycinnamate inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 amidotrizoic acid multiple interactions ISO RGD:2069 6480464 telmisartan inhibits the reaction [Diatrizoate results in increased expression of AGT protein] CTD PMID:19452295 amidotrizoic acid increases expression ISO RGD:2069 6480464 Diatrizoate results in increased expression of AGT protein CTD PMID:19452295 amiloride multiple interactions ISO RGD:2069 6480464 Amiloride inhibits the reaction [AGT protein results in increased expression of ATP1A1 mRNA] CTD PMID:14630723 amiloride increases expression EXP 6480464 Amiloride results in increased expression of AGT protein modified form CTD PMID:7357812 amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of AGT mRNA, Amiodarone results in increased expression of AGT protein CTD PMID:17214612 amiodarone affects expression ISO RGD:2069 6480464 Amiodarone affects the expression of AGT mRNA CTD PMID:19483382 amiodarone increases expression ISO RGD:2069 6480464 Amiodarone results in increased expression of AGT mRNA, Amiodarone results in increased expression of AGT protein CTD PMID:17214612 amiodarone multiple interactions EXP 6480464 [FOS protein co-treated with JUN protein] promotes the reaction [Amiodarone results in increased expression of AGT mRNA], Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA] CTD PMID:17214612 amitrole multiple interactions ISO RGD:2069 6480464 Amitrole promotes the reaction [AGT protein results in increased degradation of NFKBIA protein] CTD PMID:10712386 amlodipine multiple interactions EXP 6480464 Amlodipine inhibits the reaction [AGT results in decreased expression of BCL2 mRNA] more ... CTD PMID:21376258 ammonia increases secretion ISO RGD:10118 6480464 AGT protein results in increased secretion of Ammonia CTD PMID:18287403 ammonia increases chemical synthesis ISO RGD:10118 6480464 AGT protein results in increased chemical synthesis of Ammonia CTD PMID:18287403 ammonium chloride affects expression ISO RGD:2069 6480464 Ammonium Chloride affects the expression of AGT mRNA CTD PMID:16483693 apocynin decreases activity ISO RGD:2069 6480464 acetovanillone results in decreased activity of AGT protein CTD PMID:17224469 apocynin multiple interactions ISO RGD:2069 6480464 acetovanillone inhibits the reaction [AGT protein results in decreased export of Sodium] more ... CTD PMID:14597645 more ... apocynin multiple interactions ISO RGD:10118 6480464 acetovanillone inhibits the reaction [AGT protein results in increased abundance of Superoxides], acetovanillone inhibits the reaction [AGT protein results in increased expression of EDN1 mRNA] CTD PMID:17391658 apocynin multiple interactions EXP 6480464 [acetovanillone co-treated with AGT protein] results in increased expression of and affects the localization of NFE2L2 protein, acetovanillone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 , PMID:27983965 arachidonic acid multiple interactions ISO RGD:10118 6480464 Eicosapentaenoic Acid inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid], Quinacrine inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid] CTD PMID:16257180 atenolol affects response to substance EXP 6480464 AGT gene SNP affects the susceptibility to Atenolol CTD PMID:14700505 atenolol decreases expression EXP 6480464 Atenolol results in decreased expression of AGT protein CTD PMID:14639093 atorvastatin calcium multiple interactions ISO RGD:2069 6480464 Atorvastatin inhibits the reaction [AGT protein results in decreased expression of SOD1 protein] more ... CTD PMID:19451411 bafilomycin A1 multiple interactions ISO RGD:2069 6480464 bafilomycin A1 inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 BAPTA multiple interactions ISO RGD:10118 6480464 1 more ... CTD PMID:12606818 benazepril decreases expression EXP 6480464 benazepril results in decreased expression of AGT protein, benazepril results in decreased expression of AGT protein modified form CTD PMID:12676074 , PMID:18390891 benazepril affects response to substance EXP 6480464 AGT gene SNP affects the susceptibility to benazepril CTD PMID:17261659 benazepril multiple interactions ISO RGD:2069 6480464 benazepril inhibits the reaction [Doxorubicin results in increased expression of AGT protein modified form] more ... CTD PMID:10515446 more ... benazepril decreases expression ISO RGD:2069 6480464 benazepril results in decreased expression of AGT protein, benazepril results in decreased expression of AGT protein modified form CTD PMID:11501062 more ... benazepril multiple interactions EXP 6480464 [AGT gene polymorphism co-treated with ACE2 gene polymorphism] affects the susceptibility to benazepril more ... CTD PMID:12676074 more ... benidipine multiple interactions EXP 6480464 [Valsartan co-treated with benidipine] inhibits the reaction [AGT protein results in increased abundance of Aldosterone] more ... CTD PMID:18331727 benzbromarone affects expression ISO RGD:2069 6480464 Benzbromarone affects the expression of AGT mRNA CTD PMID:19483382 benzo[a]pyrene decreases expression ISO RGD:10118 6480464 Benzo(a)pyrene results in decreased expression of AGT mRNA CTD PMID:19770486 , PMID:27195522 benzo[a]pyrene increases expression ISO RGD:2069 6480464 Benzo(a)pyrene results in increased expression of AGT mRNA CTD PMID:22374506 benzo[a]pyrene multiple interactions ISO RGD:10118 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to AGT promoter] CTD PMID:19654925 beta-D-glucosamine increases expression ISO RGD:10118 6480464 Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 biopterin multiple interactions ISO RGD:10118 6480464 ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Biopterin analog] CTD PMID:17272743 biopterin decreases abundance ISO RGD:10118 6480464 AGT protein results in decreased abundance of Biopterin analog CTD PMID:17272743 bis(2-ethylhexyl) phthalate decreases expression ISO RGD:2069 6480464 Diethylhexyl Phthalate results in decreased expression of AGT mRNA CTD PMID:20920545 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of AGT mRNA CTD PMID:31163220 bis(2-ethylhexyl) phthalate affects expression ISO RGD:2069 6480464 Diethylhexyl Phthalate affects the expression of AGT protein modified form CTD PMID:22677342 bisphenol A decreases expression ISO RGD:2069 6480464 bisphenol A results in decreased expression of AGT mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:2069 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [bisphenol A results in increased expression of AGT mRNA] more ... CTD PMID:30677511 bisphenol A multiple interactions EXP 6480464 4-(6-bromo-1 more ... CTD PMID:30677511 bisphenol A increases expression ISO RGD:2069 6480464 bisphenol A results in increased expression of AGT mRNA, bisphenol A results in increased expression of AGT protein CTD PMID:30677511 bisphenol A increases methylation ISO RGD:10118 6480464 bisphenol A results in increased methylation of AGT promoter CTD PMID:27312807 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of AGT mRNA, bisphenol A results in increased expression of AGT protein CTD PMID:27685785 , PMID:30677511 bisphenol A increases expression ISO RGD:10118 6480464 bisphenol A results in increased expression of AGT mRNA, bisphenol A results in increased expression of AGT protein CTD PMID:25103225 Bisphenol A diglycidyl ether multiple interactions ISO RGD:2069 6480464 2 more ... CTD PMID:18278065 , PMID:25874449 boric acid multiple interactions ISO RGD:10118 6480464 boric acid inhibits the reaction [[Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of AGT mRNA] CTD PMID:28285642 BQ 123 multiple interactions ISO RGD:10118 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of COL1A1 protein], EDN1 protein affects the reaction [cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of COL1A1 protein]] CTD PMID:17391658 BQ 123 multiple interactions ISO RGD:2069 6480464 cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of MYL2 protein], cyclo(Trp-Asp-Pro-Val-Leu) inhibits the reaction [AGT protein results in increased expression of NPPA protein] CTD PMID:15007106 brefeldin A multiple interactions ISO RGD:2069 6480464 Brefeldin A inhibits the reaction [AGT protein results in increased phosphorylation of AKT1 protein] CTD PMID:15525798 brimonidine tartrate multiple interactions ISO RGD:2069 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:18250367 Brodifacoum increases expression ISO RGD:2069 6480464 bromfenacoum results in increased expression of AGT protein CTD PMID:28903499 butan-1-ol multiple interactions EXP 6480464 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK1 protein], 1-Butanol inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:12890486 butan-1-ol multiple interactions ISO RGD:2069 6480464 1-Butanol inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] more ... CTD PMID:14613874 , PMID:15525798 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of AGT mRNA CTD PMID:26079696 cadmium atom decreases activity ISO RGD:2069 6480464 Cadmium results in decreased activity of AGT protein CTD PMID:11369112 cadmium atom affects binding EXP 6480464 AGT protein binds to Cadmium CTD PMID:23896426 cadmium dichloride multiple interactions ISO RGD:10118 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA CTD PMID:19840844 caffeine increases expression ISO RGD:2069 6480464 Caffeine results in increased expression of AGT protein CTD PMID:30423288 calciol decreases expression ISO RGD:10118 6480464 Cholecalciferol results in decreased expression of AGT mRNA CTD PMID:16508948 calcium atom increases uptake EXP 6480464 AGT protein results in increased uptake of Calcium CTD PMID:18331727 calcium atom affects localization ISO RGD:2069 6480464 AGT protein affects the localization of Calcium CTD PMID:21613610 calcium atom multiple interactions ISO RGD:2069 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:21613610 calcium atom increases abundance ISO RGD:2069 6480464 [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species CTD PMID:18854758 calcium atom multiple interactions ISO RGD:10118 6480464 Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein], Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:10660688 calcium atom multiple interactions EXP 6480464 benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium], Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] CTD PMID:18331727 calcium(0) increases uptake EXP 6480464 AGT protein results in increased uptake of Calcium CTD PMID:18331727 calcium(0) affects localization ISO RGD:2069 6480464 AGT protein affects the localization of Calcium CTD PMID:21613610 calcium(0) multiple interactions ISO RGD:2069 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:21613610 calcium(0) increases abundance ISO RGD:2069 6480464 [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species CTD PMID:18854758 calcium(0) multiple interactions ISO RGD:10118 6480464 Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein], Calcium deficiency inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein] CTD PMID:10660688 calcium(0) multiple interactions EXP 6480464 benidipine inhibits the reaction [AGT protein results in increased uptake of Calcium], Mibefradil inhibits the reaction [AGT protein results in increased uptake of Calcium] CTD PMID:18331727 candesartan multiple interactions EXP 6480464 candesartan inhibits the reaction [[AGT co-treated with REN] results in increased abundance of Aldosterone] more ... CTD PMID:18551021 , PMID:18679781 candesartan multiple interactions ISO RGD:2069 6480464 candesartan inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] more ... CTD PMID:10525314 more ... candesartan multiple interactions ISO RGD:10118 6480464 candesartan inhibits the reaction [AGT protein modified form results in increased expression of COL1A2 protein] more ... CTD PMID:11729239 , PMID:12065685 Candesartan cilexetil multiple interactions EXP 6480464 candesartan cilexetil inhibits the reaction [AGT protein results in increased expression of ICAM1 mRNA], candesartan cilexetil inhibits the reaction [AGT protein results in increased secretion of ICAM1 protein] CTD PMID:10517737 Candesartan cilexetil multiple interactions ISO RGD:2069 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of AGT protein modified form] CTD PMID:27889505 Candesartan cilexetil increases expression ISO RGD:2069 6480464 candesartan cilexetil results in increased expression of AGT protein modified form CTD PMID:22120037 Candesartan cilexetil decreases activity EXP 6480464 candesartan cilexetil results in decreased activity of AGT protein CTD PMID:15361886 carbon monoxide decreases response to substance ISO RGD:10118 6480464 AGT protein results in decreased susceptibility to Carbon Monoxide CTD PMID:18174886 carbon nanotube affects expression ISO RGD:10118 6480464 Nanotubes, Carbon affects the expression of AGT mRNA CTD PMID:23845593 carbonyl cyanide p-trifluoromethoxyphenylhydrazone multiple interactions ISO RGD:2069 6480464 [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 carmustine decreases response to substance EXP 6480464 AGT protein mutant form results in decreased susceptibility to Carmustine, AGT protein results in decreased susceptibility to Carmustine CTD PMID:11034089 carvedilol multiple interactions ISO RGD:2069 6480464 [Losartan co-treated with carvedilol] results in decreased susceptibility to AGT protein modified form more ... CTD PMID:15741261 more ... carvedilol decreases response to substance ISO RGD:2069 6480464 carvedilol results in decreased susceptibility to AGT protein modified form CTD PMID:19183357 more ... carvedilol decreases response to substance EXP 6480464 carvedilol results in decreased susceptibility to AGT protein modified form CTD PMID:12538430 carvedilol multiple interactions EXP 6480464 carvedilol inhibits the reaction [AGT protein modified form promotes the reaction [Phenylephrine results in increased abundance of Inositol Phosphates]], carvedilol inhibits the reaction [AGT protein modified form results in increased susceptibility to Phenylephrine] CTD PMID:16794485 carvedilol decreases expression EXP 6480464 carvedilol results in decreased expression of AGT protein CTD PMID:12004934 catechin multiple interactions EXP 6480464 [Quercetin co-treated with Catechin] inhibits the reaction [AGT protein affects the localization of NCF1 protein] CTD PMID:22295890 CCCP multiple interactions ISO RGD:2069 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT mRNA], Carbonyl Cyanide m-Chlorophenyl Hydrazone inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 chlorpyrifos increases expression ISO RGD:10118 6480464 Chlorpyrifos results in increased expression of AGT mRNA CTD PMID:20350560 cholesterol multiple interactions ISO RGD:10118 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AGT protein] CTD PMID:19028402 cholesterol multiple interactions ISO RGD:2069 6480464 [Puromycin Aminonucleoside co-treated with Cholesterol] results in increased expression of AGT mRNA more ... CTD PMID:12495295 , PMID:19109942 cholesterol affects abundance ISO RGD:2069 6480464 AGT protein affects the abundance of Cholesterol CTD PMID:19109942 cholesterol increases expression ISO RGD:10118 6480464 Cholesterol results in increased expression of AGT protein CTD PMID:19028402 chromium atom decreases expression ISO RGD:2069 6480464 Chromium results in decreased expression of AGT protein CTD PMID:18374418 chromium(3+) decreases expression ISO RGD:2069 6480464 Chromium results in decreased expression of AGT protein CTD PMID:18374418 chymostatin multiple interactions ISO RGD:2069 6480464 Enalapril affects the reaction [chymostatin results in decreased susceptibility to AGT protein modified form] CTD PMID:21602471 chymostatin decreases response to substance ISO RGD:2069 6480464 chymostatin results in decreased susceptibility to AGT protein modified form CTD PMID:21602471 chymostatin decreases expression ISO RGD:10118 6480464 chymostatin results in decreased expression of AGT protein modified form CTD PMID:18300870 ciglitazone decreases response to substance ISO RGD:2069 6480464 ciglitazone results in decreased susceptibility to AGT protein modified form CTD PMID:16820301 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of AGT mRNA CTD PMID:20705681 cisplatin increases expression ISO RGD:10118 6480464 Cisplatin results in increased expression of AGT mRNA CTD PMID:26546572 clofibrate multiple interactions ISO RGD:10118 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of AGT mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of AGT mRNA] CTD PMID:17585979 clofibrate decreases response to substance ISO RGD:2069 6480464 Clofibrate results in decreased susceptibility to AGT protein, Clofibrate results in decreased susceptibility to AGT protein modified form CTD PMID:18300857 , PMID:21098870 clofibrate affects expression ISO RGD:2069 6480464 Clofibrate affects the expression of AGT mRNA CTD PMID:19483382 clofibrate decreases expression ISO RGD:10118 6480464 Clofibrate results in decreased expression of AGT mRNA CTD PMID:17585979 clofibric acid multiple interactions ISO RGD:2069 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGT mRNA CTD PMID:17602206 clozapine multiple interactions EXP 6480464 Clozapine inhibits the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]], Clozapine promotes the reaction [Raclopride promotes the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]]] CTD PMID:11549694 cobalt dichloride multiple interactions ISO RGD:10118 6480464 cobaltous chloride results in increased expression of and results in increased secretion of AGT protein CTD PMID:25511041 cobalt dichloride decreases expression ISO RGD:2069 6480464 cobaltous chloride results in decreased expression of AGT mRNA CTD PMID:24386269 copper atom affects binding EXP 6480464 AGT protein binds to Copper CTD PMID:23896426 copper atom decreases abundance ISO RGD:10118 6480464 AGT protein modified form results in decreased abundance of Copper CTD PMID:22753205 copper(0) decreases abundance ISO RGD:10118 6480464 AGT protein modified form results in decreased abundance of Copper CTD PMID:22753205 copper(0) affects binding EXP 6480464 AGT protein binds to Copper CTD PMID:23896426 copper(2+) decreases abundance ISO RGD:10118 6480464 AGT protein modified form results in decreased abundance of Copper CTD PMID:22753205 copper(2+) affects binding EXP 6480464 AGT protein binds to Copper CTD PMID:23896426 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of AGT mRNA CTD PMID:19549813 copper(II) sulfate multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]] more ... CTD PMID:31144504 corticosterone increases secretion EXP 6480464 AGT protein results in increased secretion of Corticosterone CTD PMID:28235592 cortisol decreases expression EXP 6480464 Hydrocortisone results in decreased expression of AGT protein CTD PMID:7473517 cortisol increases secretion EXP 6480464 AGT protein results in increased secretion of Hydrocortisone CTD PMID:28235592 curcumin multiple interactions ISO RGD:2069 6480464 [Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein] more ... CTD PMID:26612707 cyanidin 3-O-beta-D-glucoside multiple interactions EXP 6480464 4-methyl-N1-(3-phenylpropyl)benzene-1 more ... CTD PMID:27983965 cyclosporin A increases expression ISO RGD:2069 6480464 Cyclosporine results in increased expression of AGT protein CTD PMID:14659064 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of AGT mRNA CTD PMID:20106945 more ... cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Cholic Acids] affects the expression of AGT mRNA CTD PMID:27344345 cyclosporin A decreases expression ISO RGD:10118 6480464 Cyclosporine results in decreased expression of AGT mRNA CTD PMID:23830897 cyclosporin A multiple interactions ISO RGD:2069 6480464 Enalapril inhibits the reaction [Cyclosporine results in increased expression of AGT protein] CTD PMID:14659064 cypermethrin affects expression ISO RGD:2069 6480464 cypermethrin affects the expression of AGT CTD PMID:25816392 cypermethrin multiple interactions ISO RGD:2069 6480464 Sesame Oil affects the reaction [cypermethrin affects the expression of AGT] CTD PMID:25816392 D-glucosamine increases expression ISO RGD:10118 6480464 Glucosamine results in increased expression of AGT mRNA CTD PMID:17178593 D-glucose multiple interactions EXP 6480464 (3 more ... CTD PMID:15677497 more ... D-glucose increases expression EXP 6480464 Glucose results in increased expression of AGT protein CTD PMID:16452552 D-glucose increases expression ISO RGD:2069 6480464 Glucose results in increased expression of AGT mRNA, Glucose results in increased expression of AGT protein CTD PMID:12130563 , PMID:19861503 D-glucose affects metabolic processing ISO RGD:2069 6480464 AGT protein affects the metabolism of Glucose CTD PMID:11115780 D-glucose multiple interactions ISO RGD:2069 6480464 1 more ... CTD PMID:12130563 , PMID:19861503 dexamethasone multiple interactions ISO RGD:10118 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein] results in increased expression of AGT mRNA more ... CTD PMID:16054899 more ... dexamethasone multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of AGT mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGT mRNA CTD PMID:28628672 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of AGT mRNA CTD PMID:19853017 dexamethasone multiple interactions ISO RGD:2069 6480464 Dexamethasone inhibits the reaction [AGT protein alternative form results in increased abundance of 6-Ketoprostaglandin F1 alpha], Dexamethasone inhibits the reaction [AGT protein alternative form results in increased abundance of Dinoprostone] CTD PMID:4030047 , PMID:6421564 dexamethasone increases expression ISO RGD:10118 6480464 Dexamethasone results in increased expression of AGT protein CTD PMID:7843740 dextran sulfate multiple interactions ISO RGD:10118 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AGT mRNA CTD PMID:29950665 dibenziodolium multiple interactions ISO RGD:10118 6480464 diphenyleneiodonium inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides] more ... CTD PMID:12606818 , PMID:17391658 dibenziodolium multiple interactions ISO RGD:2069 6480464 diphenyleneiodonium inhibits the reaction [AGT protein affects the localization of RHOA protein] more ... CTD PMID:16569756 , PMID:18250367 diethyl malate affects expression ISO RGD:10118 6480464 diethyl malate affects the expression of AGT mRNA CTD PMID:24814887 diminazene diaceturate increases expression ISO RGD:10118 6480464 diminazene aceturate results in increased expression of AGT protein modified form CTD PMID:25301841 dioxygen multiple interactions ISO RGD:2069 6480464 acetovanillone inhibits the reaction [AGT protein results in increased abundance of Oxygen] more ... CTD PMID:11897773 , PMID:14597645 dioxygen multiple interactions ISO RGD:10118 6480464 Oxygen deficiency results in increased expression of and results in increased secretion of AGT protein CTD PMID:25511041 dioxygen decreases expression ISO RGD:2069 6480464 Oxygen deficiency results in decreased expression of AGT protein CTD PMID:19118600 dioxygen increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Oxygen CTD PMID:14597645 diuron decreases expression ISO RGD:2069 6480464 Diuron results in decreased expression of AGT mRNA CTD PMID:25152437 dopamine multiple interactions EXP 6480464 Clozapine inhibits the reaction [Dopamine promotes the reaction [AGT protein results in increased secretion of Aldosterone]] more ... CTD PMID:11549694 dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [AGT protein results in increased phosphorylation of PPP1R12A protein]] CTD PMID:24965170 dorsomorphin multiple interactions ISO RGD:10118 6480464 dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [AGT protein results in increased activity of RHOA protein]], dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [AGT protein results in increased phosphorylation of PPP1R12A protein]] CTD PMID:24965170 doxorubicin multiple interactions ISO RGD:2069 6480464 benazepril inhibits the reaction [Doxorubicin results in increased expression of AGT protein modified form], wulingsan inhibits the reaction [Doxorubicin results in increased expression of AGT protein] CTD PMID:10515446 more ... doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of AGT mRNA CTD PMID:29803840 doxorubicin increases expression ISO RGD:2069 6480464 Doxorubicin results in increased expression of AGT protein, Doxorubicin results in increased expression of AGT protein modified form CTD PMID:10515446 more ... doxycycline multiple interactions ISO RGD:2069 6480464 Doxycycline inhibits the reaction [AGT protein modified form results in increased activity of MMP2 protein], Doxycycline inhibits the reaction [AGT protein modified form results in increased activity of MMP9 protein] CTD PMID:20837116 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor multiple interactions ISO RGD:2069 6480464 AGT protein alternative form inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors results in increased secretion of REN protein], Indomethacin inhibits the reaction [Angiotensin-Converting Enzyme Inhibitors results in increased expression of AGT protein alternative form] CTD PMID:3078272 , PMID:6753910 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor decreases expression EXP 6480464 Angiotensin-Converting Enzyme Inhibitors results in decreased expression of AGT protein modified form CTD PMID:2474097 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor affects expression EXP 6480464 Angiotensin-Converting Enzyme Inhibitors affects the expression of AGT protein, Angiotensin-Converting Enzyme Inhibitors affects the expression of AGT protein alternative form CTD PMID:6105291 , PMID:7000102 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor decreases expression ISO RGD:2069 6480464 Angiotensin-Converting Enzyme Inhibitors results in decreased expression of AGT protein, Angiotensin-Converting Enzyme Inhibitors results in decreased expression of AGT protein alternative form CTD PMID:16413583 , PMID:9533614 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor increases expression EXP 6480464 Angiotensin-Converting Enzyme Inhibitors results in increased expression of AGT protein, Angiotensin-Converting Enzyme Inhibitors results in increased expression of AGT protein alternative form CTD PMID:1668233 , PMID:6388325 EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor increases metabolic processing ISO RGD:2069 6480464 Angiotensin-Converting Enzyme Inhibitors results in increased metabolism of AGT protein CTD PMID:17850902 Efonidipine hydrochloride multiple interactions EXP 6480464 efonidipine inhibits the reaction [AGT protein results in increased abundance of Aldosterone] CTD PMID:18331727 elcometrine multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with ST 1435] results in increased expression of AGT protein CTD PMID:17519148 emodin multiple interactions ISO RGD:2069 6480464 Emodin inhibits the reaction [AGT protein results in increased expression of MYC protein], Emodin inhibits the reaction [AGT protein results in increased expression of PCNA protein] CTD PMID:17886230 enalapril decreases activity ISO RGD:2069 6480464 Enalapril results in decreased activity of AGT protein modified form CTD PMID:6319675 enalapril affects response to substance EXP 6480464 AGT gene alternative form affects the susceptibility to Enalapril, AGT protein polymorphism affects the susceptibility to Enalapril CTD PMID:12911327 , PMID:16685205 enalapril increases expression ISO RGD:2069 6480464 Enalapril results in increased expression of AGT mRNA CTD PMID:18796534 enalapril decreases response to substance ISO RGD:10118 6480464 Enalapril results in decreased susceptibility to AGT protein modified form CTD PMID:12003776 enalapril multiple interactions ISO RGD:2069 6480464 Enalapril affects the reaction [chymostatin results in decreased susceptibility to AGT protein modified form] more ... CTD PMID:14659064 more ... enalapril decreases expression ISO RGD:10118 6480464 Enalapril results in decreased expression of AGT protein modified form CTD PMID:18300870 enalapril multiple interactions EXP 6480464 [Enalapril co-treated with Sodium Chloride] results in increased susceptibility to AGT protein modified form more ... CTD PMID:18679781 , PMID:20829712 enalapril decreases expression ISO RGD:2069 6480464 Enalapril results in decreased expression of AGT mRNA CTD PMID:1330361 enalapril decreases expression EXP 6480464 Enalapril results in decreased expression of AGT protein modified form CTD PMID:2474097 enalaprilat dihydrate decreases expression ISO RGD:2069 6480464 Enalaprilat results in decreased expression of AGT protein modified form CTD PMID:21795644 enalaprilat dihydrate multiple interactions EXP 6480464 Enalaprilat inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:16452552 endosulfan increases expression ISO RGD:2069 6480464 Endosulfan results in increased expression of AGT mRNA CTD PMID:29391264 eplerenone multiple interactions ISO RGD:10118 6480464 eplerenone inhibits the reaction [AGT protein results in increased phosphorylation of OSR1 protein], eplerenone inhibits the reaction [AGT protein results in increased phosphorylation of SLC12A3 protein] CTD PMID:20175999 ergosta-4,6,8(14),22-tetraen-3-one multiple interactions EXP 6480464 ergosta-4 more ... CTD PMID:28578904 ergosta-4,6,8(14),22-tetraen-3-one multiple interactions ISO RGD:10118 6480464 ergosta-4 more ... CTD PMID:28578904 ethanol increases secretion ISO RGD:2069 6480464 Ethanol results in increased secretion of AGT protein alternative form, Ethanol results in increased secretion of AGT protein modified form CTD PMID:22497828 , PMID:22982071 ethanol increases expression ISO RGD:10118 6480464 Ethanol results in increased expression of AGT mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:2069 6480464 Losartan inhibits the reaction [Ethanol results in increased secretion of AGT protein alternative form] CTD PMID:22982071 ethanol increases expression ISO RGD:2069 6480464 Ethanol results in increased expression of AGT protein modified form CTD PMID:22497828 , PMID:29548890 ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO RGD:2069 6480464 [Egtazic Acid co-treated with Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone] inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18854758 famotidine multiple interactions ISO RGD:2069 6480464 Famotidine inhibits the reaction [Indomethacin results in increased expression of AGT protein] CTD PMID:27645307 fenofibrate multiple interactions ISO RGD:10118 6480464 Fenofibrate affects the reaction [[AHR protein affects the susceptibility to AGT protein] which affects the expression of EDN1 mRNA] more ... CTD PMID:31016362 flavonoids multiple interactions EXP 6480464 Flavonoids inhibits the reaction [AGT protein results in decreased expression of BCL2 mRNA] more ... CTD PMID:23994555 flutamide increases expression ISO RGD:2069 6480464 Flutamide results in increased expression of AGT mRNA CTD PMID:24793618 folic acid multiple interactions ISO RGD:2069 6480464 AGT protein promotes the reaction [Folic Acid results in increased expression of PTHLH protein] more ... CTD PMID:15728788 folic acid increases localization ISO RGD:2069 6480464 Folic Acid results in increased localization of AGT protein CTD PMID:15728788 fosinopril decreases expression ISO RGD:2069 6480464 Fosinopril results in decreased expression of AGT protein CTD PMID:12411096 fructose increases expression ISO RGD:2069 6480464 Fructose results in increased expression of AGT mRNA more ... CTD PMID:11741341 more ... fructose multiple interactions ISO RGD:2069 6480464 APLN protein modified form inhibits the reaction [Fructose results in increased expression of AGT mRNA] more ... CTD PMID:30710622 fructose increases expression ISO RGD:10118 6480464 Fructose results in increased expression of AGT protein CTD PMID:16843071 fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT mRNA] CTD PMID:30677511 fulvestrant multiple interactions ISO RGD:2069 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT mRNA], Fulvestrant inhibits the reaction [bisphenol A results in increased expression of AGT protein] CTD PMID:30677511 fumonisin B1 multiple interactions EXP 6480464 fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 mRNA], fumonisin B1 inhibits the reaction [AGT protein results in increased expression of MDM2 protein] CTD PMID:18206046 fumonisin B1 decreases expression ISO RGD:10118 6480464 fumonisin B1 results in decreased expression of AGT mRNA CTD PMID:16221962 furan decreases expression ISO RGD:2069 6480464 furan results in decreased expression of AGT mRNA CTD PMID:25539665 , PMID:26194646 furosemide increases expression EXP 6480464 Furosemide results in increased expression of AGT protein modified form CTD PMID:18081357 genistein multiple interactions EXP 6480464 ESR1 mutant form inhibits the reaction [Genistein results in increased expression of AGT mRNA] CTD PMID:25136773 genistein increases expression EXP 6480464 Genistein results in increased expression of AGT mRNA CTD PMID:25136773 gentamycin increases expression ISO RGD:2069 6480464 Gentamicins results in increased expression of AGT protein CTD PMID:12495276 Ginkgoic acid multiple interactions ISO RGD:10118 6480464 ginkgolic acid inhibits the reaction [AGT protein modified form results in increased expression of ACTA2 protein] more ... CTD PMID:29524504 glucose multiple interactions EXP 6480464 (3 more ... CTD PMID:15677497 more ... glucose increases expression EXP 6480464 Glucose results in increased expression of AGT protein CTD PMID:16452552 glucose increases expression ISO RGD:2069 6480464 Glucose results in increased expression of AGT mRNA, Glucose results in increased expression of AGT protein CTD PMID:12130563 , PMID:19861503 glucose affects metabolic processing ISO RGD:2069 6480464 AGT protein affects the metabolism of Glucose CTD PMID:11115780 glucose multiple interactions ISO RGD:2069 6480464 1 more ... CTD PMID:12130563 , PMID:19861503 glutathione multiple interactions ISO RGD:10118 6480464 ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Glutathione] more ... CTD PMID:17272743 , PMID:30703374 glutathione multiple interactions EXP 6480464 AGT protein modified form results in increased chemical synthesis of [4-oxo-2-nonenal binds to Glutathione] CTD PMID:31144504 glutathione decreases abundance ISO RGD:10118 6480464 AGT protein modified form results in decreased abundance of Glutathione, AGT protein results in decreased abundance of Glutathione CTD PMID:17272743 , PMID:30703374 glutathione disulfide multiple interactions ISO RGD:10118 6480464 ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Glutathione Disulfide] CTD PMID:17272743 glutathione disulfide increases export ISO RGD:10118 6480464 AGT protein results in increased export of Glutathione Disulfide CTD PMID:17272743 glutathione disulfide decreases abundance ISO RGD:10118 6480464 AGT protein results in decreased abundance of Glutathione Disulfide CTD PMID:17272743 glycerol increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Glycerol CTD PMID:15741261 glycerol multiple interactions ISO RGD:2069 6480464 carvedilol inhibits the reaction [AGT protein results in increased abundance of Glycerol], Losartan inhibits the reaction [AGT protein results in increased abundance of Glycerol] CTD PMID:15741261 glycochenodeoxycholic acid decreases response to substance ISO RGD:2069 6480464 AGT protein results in decreased susceptibility to Glycochenodeoxycholic Acid CTD PMID:23300732 glycochenodeoxycholic acid multiple interactions ISO RGD:2069 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] more ... CTD PMID:23300732 heparin multiple interactions ISO RGD:2069 6480464 Heparin inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 hydralazine multiple interactions ISO RGD:2069 6480464 Hydralazine affects the reaction [AGT protein results in increased abundance of Fatty Acids, Nonesterified] more ... CTD PMID:16344371 , PMID:19109942 hydralazine decreases response to substance ISO RGD:10118 6480464 Hydralazine results in decreased susceptibility to AGT protein modified form CTD PMID:21289285 hydrazines decreases expression ISO RGD:10118 6480464 Hydrazines results in decreased expression of AGT mRNA CTD PMID:21647536 hydrogen peroxide increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Hydrogen Peroxide CTD PMID:12606818 hydrogen peroxide increases expression ISO RGD:10118 6480464 Hydrogen Peroxide results in increased expression of AGT mRNA, Hydrogen Peroxide results in increased expression of AGT protein modified form CTD PMID:30710622 hydrogen peroxide increases chemical synthesis ISO RGD:2069 6480464 AGT protein modified form results in increased chemical synthesis of Hydrogen Peroxide CTD PMID:29609002 hydrogen peroxide multiple interactions ISO RGD:10118 6480464 [GMFB protein co-treated with AGT protein] results in increased abundance of Hydrogen Peroxide CTD PMID:12791701 hydrogen peroxide increases expression ISO RGD:2069 6480464 Hydrogen Peroxide results in increased expression of AGT protein modified form CTD PMID:15867141 hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of AGT mRNA CTD PMID:20044591 hydrogen peroxide increases abundance ISO RGD:2069 6480464 AGT protein modified form results in increased abundance of Hydrogen Peroxide, AGT protein results in increased abundance of Hydrogen Peroxide CTD PMID:10712386 , PMID:20881940 hydrogen peroxide multiple interactions ISO RGD:2069 6480464 Hydrogen Peroxide promotes the reaction [Glucose results in increased expression of AGT mRNA] more ... CTD PMID:12130563 , PMID:15607907 hydrogen sulfide multiple interactions EXP 6480464 Hydrogen Sulfide promotes the reaction [AGT protein modified form results in increased chemical synthesis of Nitric Oxide] CTD PMID:29084084 ibuprofen increases expression ISO RGD:2069 6480464 Ibuprofen results in increased expression of AGT protein CTD PMID:18096423 ICI 118551 multiple interactions ISO RGD:10118 6480464 ICI 118551 inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]] CTD PMID:7843740 imidaprilat multiple interactions ISO RGD:10118 6480464 imidaprilat inhibits the reaction [AGT protein results in increased activity of and results in increased localization of PRKCA protein] CTD PMID:16257180 imperatorin multiple interactions ISO RGD:2069 6480464 imperatorin analog inhibits the reaction [AGT protein results in decreased expression of ACTA2 protein], imperatorin analog inhibits the reaction [AGT protein results in increased expression of SPP1 protein] CTD PMID:25727310 indometacin multiple interactions ISO RGD:2069 6480464 aliskiren inhibits the reaction [Indomethacin results in increased expression of AGT protein] more ... CTD PMID:27645307 , PMID:6753910 indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bis(4-hydroxyphenyl)sulfone] results in decreased expression of AGT mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of AGT mRNA CTD PMID:28628672 indometacin increases expression ISO RGD:2069 6480464 Indomethacin results in increased expression of AGT protein CTD PMID:27645307 indometacin decreases expression EXP 6480464 Indomethacin results in decreased expression of AGT protein CTD PMID:3038419 iohexol increases expression ISO RGD:2069 6480464 Iohexol results in increased expression of AGT protein CTD PMID:19452295 iohexol multiple interactions ISO RGD:2069 6480464 telmisartan inhibits the reaction [Iohexol results in increased expression of AGT protein] CTD PMID:19452295 irbesartan affects response to substance EXP 6480464 AGT gene polymorphism affects the susceptibility to irbesartan, AGT gene SNP affects the susceptibility to irbesartan CTD PMID:11910301 , PMID:15614026 irbesartan multiple interactions EXP 6480464 irbesartan inhibits the reaction [AGT protein modified form results in increased susceptibility to Phenylephrine] CTD PMID:16794485 irbesartan increases expression EXP 6480464 irbesartan results in increased expression of AGT protein CTD PMID:10082498 , PMID:14639093 irbesartan multiple interactions ISO RGD:2069 6480464 irbesartan inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] CTD PMID:23300732 irbesartan multiple interactions ISO RGD:10118 6480464 Cholesterol inhibits the reaction [irbesartan results in increased expression of AGT protein] CTD PMID:19028402 irinotecan decreases expression EXP 6480464 Irinotecan analog results in decreased expression of AGT mRNA CTD PMID:18927307 isoprenaline multiple interactions ISO RGD:10118 6480464 adenosine-3' more ... CTD PMID:7843740 isoprenaline increases expression ISO RGD:2069 6480464 Isoproterenol results in increased expression of AGT protein CTD PMID:11709406 more ... isoprenaline multiple interactions ISO RGD:2069 6480464 AGT affects the reaction [Isoproterenol results in decreased expression of ADRB1 mRNA] more ... CTD PMID:11709406 more ... isoprenaline increases expression ISO RGD:10118 6480464 Isoproterenol results in increased expression of AGT mRNA, Isoproterenol results in increased expression of AGT protein CTD PMID:19023134 , PMID:20003209 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of AGT protein CTD PMID:1653766 isoprenaline multiple interactions EXP 6480464 Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:1653766 isorhamnetin multiple interactions ISO RGD:2069 6480464 3-methylquercetin inhibits the reaction [AGT protein results in increased expression of NCF1 protein] CTD PMID:17374653 ketamine decreases expression EXP 6480464 Ketamine results in decreased expression of AGT protein CTD PMID:6349867 ketamine increases expression ISO RGD:2069 6480464 Ketamine results in increased expression of AGT mRNA CTD PMID:20080153 L-ascorbic acid multiple interactions ISO RGD:2069 6480464 Ascorbic Acid inhibits the reaction [AGT protein modified form results in decreased hydroxylation of HIF1A protein], Ascorbic Acid inhibits the reaction [AGT protein modified form results in increased expression of TIMP1 protein] CTD PMID:20881940 L-ascorbic acid multiple interactions EXP 6480464 [Ascorbic Acid co-treated with Copper Sulfate] promotes the reaction [AGT protein modified form results in increased chemical synthesis of [4-hydroxy-2-nonenal binds to AGT protein modified form]] more ... CTD PMID:26111765 , PMID:31144504 L-erythro-biopterin decreases abundance ISO RGD:10118 6480464 AGT protein results in decreased abundance of Biopterin analog CTD PMID:17272743 L-erythro-biopterin multiple interactions ISO RGD:10118 6480464 ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Biopterin analog] CTD PMID:17272743 L-ethionine affects expression ISO RGD:2069 6480464 Ethionine affects the expression of AGT mRNA CTD PMID:19483382 labetalol decreases expression EXP 6480464 Labetalol results in decreased expression of AGT protein CTD PMID:14627 lactacystin multiple interactions ISO RGD:2069 6480464 lactacystin inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452 lead(0) decreases activity ISO RGD:2069 6480464 Lead results in decreased activity of AGT protein CTD PMID:11369112 lead(0) affects binding EXP 6480464 AGT protein binds to Lead CTD PMID:23896426 lead(2+) decreases activity ISO RGD:2069 6480464 Lead results in decreased activity of AGT protein CTD PMID:11369112 lead(2+) affects binding EXP 6480464 AGT protein binds to Lead CTD PMID:23896426 levonorgestrel multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of AGT protein CTD PMID:17519148 linoleic acid hydroperoxide multiple interactions EXP 6480464 Ascorbic Acid promotes the reaction [linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form] CTD PMID:26111765 linoleic acid hydroperoxide increases lipidation EXP 6480464 linoleic acid hydroperoxide results in increased lipidation of AGT protein modified form CTD PMID:26111765 lipoic acid multiple interactions ISO RGD:10118 6480464 [Thioctic Acid co-treated with Dietary Fats] results in decreased expression of AGT mRNA CTD PMID:27260466 lipopolysaccharide increases expression ISO RGD:2069 6480464 Lipopolysaccharides results in increased expression of AGT mRNA CTD PMID:12575980 lipopolysaccharide multiple interactions ISO RGD:2069 6480464 AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA], candesartan inhibits the reaction [AGT protein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]] CTD PMID:10525314 lipopolysaccharide decreases expression ISO RGD:2069 6480464 Lipopolysaccharides results in decreased expression of AGT protein CTD PMID:19118600 lisinopril dihydrate decreases expression EXP 6480464 Lisinopril results in decreased expression of AGT protein CTD PMID:8393685 lisinopril dihydrate affects response to substance EXP 6480464 AGT gene alternative form affects the susceptibility to Lisinopril CTD PMID:16685205 lisinopril dihydrate increases expression ISO RGD:2069 6480464 Lisinopril results in increased expression of AGT mRNA CTD PMID:8915971 losartan decreases activity ISO RGD:10118 6480464 [Losartan results in decreased activity of AGT protein] which results in decreased activity of TGFB1 protein, Losartan results in decreased activity of AGT protein CTD PMID:21152098 losartan increases expression EXP 6480464 Losartan results in increased expression of AGT protein CTD PMID:10082498 more ... losartan decreases response to substance ISO RGD:2069 6480464 Losartan results in decreased susceptibility to AGT protein modified form CTD PMID:19183357 more ... losartan decreases activity ISO RGD:2069 6480464 Losartan results in decreased activity of AGT protein, Losartan results in decreased activity of AGT protein modified form CTD PMID:12084390 more ... losartan increases expression ISO RGD:2069 6480464 Losartan results in increased expression of AGT protein CTD PMID:12411096 more ... losartan decreases expression ISO RGD:2069 6480464 Losartan results in decreased expression of AGT protein more ... CTD PMID:15213268 more ... losartan multiple interactions ISO RGD:2069 6480464 [Losartan co-treated with Carvedilol] results in decreased susceptibility to AGT protein modified form more ... CTD PMID:11463773 more ... losartan multiple interactions ISO RGD:10118 6480464 Losartan inhibits the reaction [AGT protein affects the localization of CTNNB1 protein] more ... CTD PMID:10400907 more ... losartan decreases activity EXP 6480464 Losartan results in decreased activity of AGT protein CTD PMID:15361886 losartan multiple interactions EXP 6480464 [Losartan co-treated with ICG 001] inhibits the reaction [AGT protein results in decreased expression of NPHS2 protein] more ... CTD PMID:10517737 more ... LY294002 multiple interactions ISO RGD:2069 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] more ... CTD PMID:15121739 more ... malonaldehyde increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Malondialdehyde CTD PMID:19451411 malonaldehyde multiple interactions ISO RGD:10118 6480464 FNDC5 protein inhibits the reaction [AGT protein modified form results in increased abundance of Malondialdehyde] CTD PMID:30703374 malonaldehyde increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Malondialdehyde CTD PMID:30703374 malonaldehyde affects binding EXP 6480464 Malondialdehyde binds to AGT protein modified form CTD PMID:26111765 malonaldehyde multiple interactions ISO RGD:2069 6480464 Atorvastatin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde], isorhapontigenin inhibits the reaction [AGT protein results in increased abundance of Malondialdehyde] CTD PMID:15607907 , PMID:19451411 mangiferin multiple interactions ISO RGD:2069 6480464 mangiferin inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA] more ... CTD PMID:17645561 , PMID:19706694 melatonin decreases expression ISO RGD:2069 6480464 Melatonin results in decreased expression of AGT protein CTD PMID:19018803 mercaptopurine decreases expression ISO RGD:2069 6480464 Mercaptopurine results in decreased expression of AGT mRNA CTD PMID:23358152 mercury dichloride increases expression ISO RGD:2069 6480464 Mercuric Chloride results in increased expression of AGT protein, Mercuric Chloride results in increased expression of AGT protein modified form CTD PMID:18093879 , PMID:22822941 metformin multiple interactions ISO RGD:10118 6480464 Metformin inhibits the reaction [AGT protein results in increased activity of and results in increased phosphorylation of HMGCR protein] more ... CTD PMID:29499335 methotrexate affects expression ISO RGD:10118 6480464 Methotrexate affects the expression of AGT mRNA CTD PMID:18502557 methylglyoxal affects expression ISO RGD:2069 6480464 Pyruvaldehyde affects the expression of AGT protein CTD PMID:24402234 Mibefradil multiple interactions EXP 6480464 Mibefradil inhibits the reaction [AGT protein results in increased abundance of Aldosterone] more ... CTD PMID:18331727 microcystin RR increases expression ISO RGD:10118 6480464 microcystin RR results in increased expression of AGT mRNA, microcystin RR results in increased expression of AGT protein CTD PMID:28330766 microcystin RR multiple interactions ISO RGD:10118 6480464 aliskiren inhibits the reaction [microcystin RR results in increased expression of AGT protein] CTD PMID:28330766 midostaurin multiple interactions ISO RGD:2069 6480464 midostaurin inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] CTD PMID:14613874 miquelianin multiple interactions EXP 6480464 quercetin 3-O-glucuronide analog inhibits the reaction [AGT protein results in increased phosphorylation of JUN protein] CTD PMID:12054679 mithramycin multiple interactions ISO RGD:2069 6480464 Plicamycin inhibits the reaction [AGT protein results in increased expression of TGFB1 mRNA] CTD PMID:25398788 monocrotaline increases expression ISO RGD:2069 6480464 Monocrotaline results in increased expression of AGT protein CTD PMID:16936438 montelukast affects response to substance EXP 6480464 AGT polymorphism affects the susceptibility to montelukast CTD PMID:21624492 mycophenolic acid decreases expression ISO RGD:2069 6480464 Mycophenolic Acid results in decreased expression of AGT protein alternative form CTD PMID:15213268 N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO RGD:2069 6480464 N more ... CTD PMID:22427991 N-acetyl-L-cysteine multiple interactions ISO RGD:2069 6480464 Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein] CTD PMID:15849355 N-acetyl-L-cysteine multiple interactions ISO RGD:10118 6480464 Acetylcysteine inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species] CTD PMID:30703374 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:2069 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Curcumin binds to carboxymethyl-chitosan analog] inhibits the reaction [AGT protein modified form results in decreased degradation of TP53 protein]], benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [AGT protein results in increased degradation of SYP protein] CTD PMID:18487452 , PMID:26612707 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of AGT mRNA CTD PMID:24810058 N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO RGD:10118 6480464 [Methylnitronitrosoguanidine co-treated with Cadmium Chloride] results in increased expression of AGT mRNA more ... CTD PMID:19840844 N-nitrosodiethylamine multiple interactions ISO RGD:10118 6480464 IKBKB protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA], MAPK14 protein inhibits the reaction [Diethylnitrosamine results in increased expression of AGT mRNA] CTD PMID:18691550 N-nitrosodiethylamine multiple interactions ISO RGD:2069 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of AGT mRNA, [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AGT mRNA CTD PMID:17602206 , PMID:28943392 N-nitrosodimethylamine increases expression ISO RGD:2069 6480464 Dimethylnitrosamine results in increased expression of AGT protein CTD PMID:15504291 N-nitrosodimethylamine multiple interactions ISO RGD:2069 6480464 valsartan inhibits the reaction [Dimethylnitrosamine results in increased expression of AGT protein] CTD PMID:15504291 naringin multiple interactions EXP 6480464 naringin inhibits the reaction [AGT protein results in increased expression of CYP11B2 mRNA], naringin inhibits the reaction [AGT protein results in increased secretion of Aldosterone] CTD PMID:22798349 nebivolol multiple interactions ISO RGD:2069 6480464 Nebivolol inhibits the reaction [AGT protein affects the localization of NCF2 protein] more ... CTD PMID:16940222 nickel atom affects binding EXP 6480464 AGT protein binds to Nickel CTD PMID:23896426 nicorandil multiple interactions ISO RGD:10118 6480464 Nicorandil inhibits the reaction [AGT protein modified form results in increased expression of XDH protein] CTD PMID:22622455 nicotinic acid multiple interactions EXP 6480464 Niacin inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] CTD PMID:18550065 nicotinic acid decreases expression ISO RGD:2069 6480464 Niacin results in decreased expression of AGT protein CTD PMID:18374418 nimesulide decreases activity ISO RGD:10118 6480464 nimesulide results in decreased activity of AGT CTD PMID:12065685 nitric oxide decreases secretion EXP 6480464 AGT protein modified form results in decreased secretion of Nitric Oxide CTD PMID:17666345 nitric oxide increases chemical synthesis EXP 6480464 AGT protein modified form results in increased chemical synthesis of Nitric Oxide CTD PMID:29084084 nitric oxide increases activity ISO RGD:2069 6480464 Nitric Oxide deficiency results in increased activity of AGT protein modified form CTD PMID:12198334 nitric oxide increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Nitric Oxide CTD PMID:14597853 nitric oxide increases secretion ISO RGD:2069 6480464 AGT protein alternative form results in increased secretion of Nitric Oxide CTD PMID:18990443 nitric oxide decreases abundance ISO RGD:10118 6480464 AGT protein results in decreased abundance of Nitric Oxide CTD PMID:17272743 nitric oxide multiple interactions ISO RGD:2069 6480464 AGT protein alternative form promotes the reaction [NOS3 protein results in increased chemical synthesis of Nitric Oxide] more ... CTD PMID:14597853 more ... nitric oxide multiple interactions ISO RGD:10118 6480464 ABCC1 protein affects the reaction [AGT protein results in decreased abundance of Nitric Oxide] CTD PMID:17272743 nitric oxide multiple interactions EXP 6480464 candesartan inhibits the reaction [AGT protein results in increased chemical synthesis of Nitric Oxide] more ... CTD PMID:17666345 more ... nitrites increases abundance ISO RGD:2069 6480464 AGT protein modified form results in increased abundance of Nitrites CTD PMID:28299329 nitrofen decreases expression ISO RGD:2069 6480464 nitrofen results in decreased expression of AGT mRNA CTD PMID:16292651 nitrofurantoin decreases activity ISO RGD:2069 6480464 Nitrofurantoin results in decreased activity of AGT protein CTD PMID:1313237 nitroprusside decreases response to substance ISO RGD:10118 6480464 AGT protein results in decreased susceptibility to Nitroprusside CTD PMID:18174886 NS-398 multiple interactions ISO RGD:2069 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [AGT protein results in increased abundance of Prostaglandins E] CTD PMID:19145780 ochratoxin A decreases expression ISO RGD:2069 6480464 ochratoxin A results in decreased expression of AGT mRNA CTD PMID:16251485 okadaic acid multiple interactions ISO RGD:10118 6480464 [Methylnitronitrosoguanidine co-treated with Okadaic Acid] results in increased expression of AGT mRNA CTD PMID:19840844 olmesartan decreases expression ISO RGD:2069 6480464 olmesartan results in decreased expression of AGT protein modified form CTD PMID:19171689 olmesartan multiple interactions EXP 6480464 [olmesartan co-treated with PD 123319] inhibits the reaction [AGT protein modified form results in increased abundance of Fatty Acids, Nonesterified], [olmesartan co-treated with PD 123319] inhibits the reaction [AGT protein modified form results in increased secretion of and results in increased abundance of Triglycerides] CTD PMID:16003179 omeprazole affects expression ISO RGD:2069 6480464 Omeprazole affects the expression of AGT mRNA CTD PMID:19483382 ouabain affects expression ISO RGD:2069 6480464 Ouabain affects the expression of AGT protein CTD PMID:16565308 ouabain increases expression ISO RGD:2069 6480464 Ouabain results in increased expression of AGT protein CTD PMID:11768735 Pachymic acid multiple interactions EXP 6480464 pachymic acid analog inhibits the reaction [AGT protein results in decreased expression of CDH1 protein] more ... CTD PMID:28578904 Pachymic acid multiple interactions ISO RGD:10118 6480464 pachymic acid analog inhibits the reaction [AGT protein results in decreased expression of HMOX1 protein] more ... CTD PMID:28578904 paclitaxel multiple interactions EXP 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of AGT mRNA CTD PMID:20705681 paracetamol multiple interactions ISO RGD:10118 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of AGT mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of AGT mRNA] CTD PMID:17585979 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of AGT mRNA CTD PMID:29067470 paraquat multiple interactions EXP 6480464 AGT protein modified form promotes the reaction [Paraquat results in increased expression of TGFB1 protein], CMA1 protein promotes the reaction [Paraquat results in increased expression of AGT protein modified form] CTD PMID:19969051 paraquat increases expression EXP 6480464 Paraquat results in increased expression of AGT mRNA, Paraquat results in increased expression of AGT protein modified form CTD PMID:19969051 paraquat increases secretion EXP 6480464 Paraquat results in increased secretion of AGT protein CTD PMID:20035857 PD 168393 multiple interactions ISO RGD:2069 6480464 PD168393 inhibits the reaction [AGT protein promotes the reaction [SP1 protein binds to TGFB1 promoter]] more ... CTD PMID:25398788 PD123319 multiple interactions EXP 6480464 [olmesartan co-treated with PD 123319] inhibits the reaction [AGT protein modified form results in increased abundance of Fatty Acids, Nonesterified] more ... CTD PMID:16003179 , PMID:18206046 PD123319 decreases response to substance ISO RGD:2069 6480464 PD 123319 results in decreased susceptibility to AGT protein CTD PMID:18300857 PD123319 decreases activity ISO RGD:2069 6480464 PD 123319 results in decreased activity of AGT protein modified form CTD PMID:9176287 , PMID:9519251 PD123319 multiple interactions ISO RGD:2069 6480464 PD 123319 affects the reaction [AGT protein promotes the reaction [PTPN6 protein binds to MTUS1 protein]] more ... CTD PMID:11115077 more ... PD123319 multiple interactions ISO RGD:10118 6480464 PD 123319 inhibits the reaction [AGT protein results in increased expression of UBE2V2 mRNA] more ... CTD PMID:16769992 more ... perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of AGT protein CTD PMID:26879310 perindopril decreases expression EXP 6480464 Perindopril results in decreased expression of AGT protein alternative form CTD PMID:2549899 , PMID:2605800 perindopril decreases expression ISO RGD:2069 6480464 Perindopril results in decreased expression of AGT protein alternative form CTD PMID:9808682 perindopril multiple interactions ISO RGD:2069 6480464 [Perindopril co-treated with racecadotril] results in increased expression of AGT protein alternative form CTD PMID:9808682 perindopril increases expression EXP 6480464 Perindopril results in increased expression of AGT protein alternative form CTD PMID:2549899 , PMID:2605800 peroxynitrous acid increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Peroxynitrous Acid CTD PMID:12606818 phenylarsine oxide multiple interactions ISO RGD:2069 6480464 oxophenylarsine inhibits the reaction [[AGT protein binds to and results in increased localization of AGTR1A protein] which results in increased expression of PTGS2 protein], oxophenylarsine inhibits the reaction [AGT protein binds to and results in increased localization of AGTR1A protein] CTD PMID:18267125 phenylephrine affects response to substance ISO RGD:2069 6480464 AGT protein affects the susceptibility to Phenylephrine CTD PMID:2298476 phenylephrine increases response to substance EXP 6480464 AGT protein modified form results in increased susceptibility to Phenylephrine CTD PMID:16794485 phenylephrine multiple interactions EXP 6480464 AGT protein modified form promotes the reaction [Phenylephrine results in increased abundance of Inositol Phosphates] more ... CTD PMID:16794485 phenylephrine increases expression ISO RGD:2069 6480464 Phenylephrine results in increased expression of AGT mRNA, Phenylephrine results in increased expression of AGT protein CTD PMID:16251426 , PMID:27094369 phenylephrine multiple interactions ISO RGD:2069 6480464 [Phenylephrine results in increased expression of AGT protein] which results in increased activity of MMP2 protein more ... CTD PMID:16251426 more ... phorbol 13-acetate 12-myristate multiple interactions ISO RGD:10118 6480464 [Methylnitronitrosoguanidine co-treated with Tetradecanoylphorbol Acetate] results in increased expression of AGT mRNA CTD PMID:19840844 phosphatidic acid increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Phosphatidic Acids CTD PMID:14613874 phosphoramidon multiple interactions ISO RGD:2069 6480464 phosphoramidon inhibits the reaction [AGT protein results in increased expression of EDNRA protein] CTD PMID:15007106 pindolol multiple interactions EXP 6480464 Pindolol inhibits the reaction [REN protein results in increased cleavage of AGT protein] CTD PMID:7104148 pioglitazone multiple interactions ISO RGD:2069 6480464 pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 mRNA], pioglitazone inhibits the reaction [AGT protein results in increased expression of KLF5 protein] CTD PMID:25874449 pirinixic acid decreases expression ISO RGD:10118 6480464 pirinixic acid results in decreased expression of AGT mRNA CTD PMID:16221962 pirinixic acid decreases expression ISO RGD:2069 6480464 pirinixic acid results in decreased expression of AGT mRNA CTD PMID:19162173 pirinixic acid affects expression ISO RGD:2069 6480464 pirinixic acid affects the expression of AGT mRNA CTD PMID:19483382 pirinixic acid increases expression ISO RGD:10118 6480464 pirinixic acid results in increased expression of AGT mRNA CTD PMID:16985257 , PMID:18445702 potassium atom decreases abundance EXP 6480464 AGT protein results in decreased abundance of Potassium CTD PMID:12869368 potassium dichromate decreases expression ISO RGD:10118 6480464 Potassium Dichromate results in decreased expression of AGT mRNA CTD PMID:23608068 pravastatin decreases expression ISO RGD:2069 6480464 Pravastatin results in decreased expression of AGT mRNA CTD PMID:27225895 pravastatin decreases expression ISO RGD:10118 6480464 Pravastatin results in decreased expression of AGT mRNA CTD PMID:27225895 progesterone multiple interactions EXP 6480464 Progesterone inhibits the reaction [AGT protein results in increased abundance of Inositol Phosphates] CTD PMID:1337236 progesterone decreases secretion EXP 6480464 AGT protein results in decreased secretion of Progesterone CTD PMID:28235592 progesterone decreases expression ISO RGD:10118 6480464 Progesterone results in decreased expression of AGT mRNA CTD PMID:22095930 propanal decreases expression EXP 6480464 propionaldehyde results in decreased expression of AGT mRNA CTD PMID:26079696 propranolol multiple interactions EXP 6480464 Propranolol inhibits the reaction [Isoproterenol results in increased expression of AGT protein], Propranolol inhibits the reaction [REN protein results in increased cleavage of AGT protein] CTD PMID:1653766 , PMID:7104148 propranolol multiple interactions ISO RGD:10118 6480464 Propranolol inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides], Propranolol inhibits the reaction [Isoproterenol promotes the reaction [Dexamethasone results in increased expression of AGT protein]] CTD PMID:12606818 , PMID:7843740 propranolol decreases expression EXP 6480464 Propranolol results in decreased expression of AGT protein CTD PMID:14627 prostaglandin E1 increases expression EXP 6480464 Alprostadil results in increased expression of AGT protein CTD PMID:9195357 prostaglandin E2 multiple interactions ISO RGD:2069 6480464 Dexamethasone inhibits the reaction [AGT protein alternative form results in increased abundance of Dinoprostone] CTD PMID:4030047 , PMID:6421564 prostaglandin E2 increases abundance ISO RGD:2069 6480464 AGT protein alternative form results in increased abundance of Dinoprostone CTD PMID:4030047 , PMID:6421564 prostaglandin I2 multiple interactions ISO RGD:2069 6480464 1-Butanol inhibits the reaction [AGT protein results in increased abundance of Epoprostenol] more ... CTD PMID:14613874 prostaglandin I2 increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Epoprostenol, AGT results in increased abundance of Epoprostenol CTD PMID:14613874 , PMID:3888613 prostaglandins E increases abundance ISO RGD:2069 6480464 AGT protein results in increased abundance of Prostaglandins E CTD PMID:19145780 , PMID:19246637 prostaglandins E multiple interactions ISO RGD:2069 6480464 N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide inhibits the reaction [AGT protein results in increased abundance of Prostaglandins E] more ... CTD PMID:19145780 , PMID:19246637 purine-6-thiol decreases expression ISO RGD:2069 6480464 Mercaptopurine results in decreased expression of AGT mRNA CTD PMID:23358152 pyrrolidine dithiocarbamate multiple interactions ISO RGD:2069 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 mRNA], pyrrolidine dithiocarbamic acid inhibits the reaction [AGT protein results in increased expression of VCAM1 protein] CTD PMID:10712386 quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of AGT mRNA CTD PMID:21632981 quercetin multiple interactions EXP 6480464 [Quercetin co-treated with Catechin] inhibits the reaction [AGT protein affects the localization of NCF1 protein] CTD PMID:22295890 quercetin multiple interactions ISO RGD:2069 6480464 PPARG protein affects the reaction [Quercetin inhibits the reaction [AGT protein results in increased expression of FOS protein]] more ... CTD PMID:17059008 more ... quercetin multiple interactions ISO RGD:10118 6480464 [Quercetin co-treated with Dietary Fats] results in decreased expression of AGT mRNA CTD PMID:27260466 quinacrine multiple interactions ISO RGD:10118 6480464 Quinacrine inhibits the reaction [AGT protein results in increased metabolism of and results in increased abundance of Arachidonic Acid] CTD PMID:16257180 quinapril decreases activity ISO RGD:2069 6480464 Quinapril results in decreased activity of AGT protein CTD PMID:15728788 quinapril multiple interactions ISO RGD:2069 6480464 Quinapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein], Quinapril promotes the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:11709406 raloxifene multiple interactions EXP 6480464 [Raloxifene Hydrochloride co-treated with Estradiol] inhibits the reaction [AGT protein results in increased phosphorylation of STAT3 protein] more ... CTD PMID:17336289 reactive oxygen species multiple interactions EXP 6480464 BCL2 mutant form promotes the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:18550065 more ... reactive oxygen species multiple interactions ISO RGD:2069 6480464 [AGT protein modified form results in increased abundance of Reactive Oxygen Species] which results in increased activity of TRPC6 protein more ... CTD PMID:15123525 more ... reactive oxygen species increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Reactive Oxygen Species CTD PMID:27099261 , PMID:30703374 reactive oxygen species multiple interactions ISO RGD:10118 6480464 [AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased abundance of Reactive Oxygen Species more ... CTD PMID:17620961 more ... reactive oxygen species increases abundance ISO RGD:2069 6480464 [AGT protein results in increased abundance of Calcium] which results in increased abundance of Reactive Oxygen Species more ... CTD PMID:15123525 more ... reactive oxygen species increases abundance EXP 6480464 AGT protein modified form results in increased abundance of Reactive Oxygen Species, AGT protein results in increased abundance of Reactive Oxygen Species CTD PMID:18550065 more ... reboxetine decreases expression EXP 6480464 reboxetine results in decreased expression of AGT protein modified form CTD PMID:16717144 resveratrol multiple interactions ISO RGD:2069 6480464 resveratrol inhibits the reaction [AGT protein modified form results in increased expression of RCAN1 mRNA] more ... CTD PMID:12237323 more ... resveratrol multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Resveratrol inhibits the reaction [AGT protein results in increased phosphorylation of PPP1R12A protein]] more ... CTD PMID:24965170 , PMID:25493383 resveratrol increases phosphorylation EXP 6480464 resveratrol results in increased phosphorylation of AGT protein CTD PMID:20709957 resveratrol multiple interactions ISO RGD:10118 6480464 [Resveratrol co-treated with Dietary Fats] results in decreased expression of AGT mRNA more ... CTD PMID:16257180 more ... resveratrol decreases response to substance EXP 6480464 resveratrol results in decreased susceptibility to AGT protein modified form CTD PMID:20429690 rotenone multiple interactions EXP 6480464 Rotenone inhibits the reaction [Glucose promotes the reaction [AGT protein results in increased phosphorylation of JAK2 protein]] CTD PMID:15677497 rotenone multiple interactions ISO RGD:10118 6480464 [AGT protein co-treated with Rotenone] results in increased expression of AGTR2 protein more ... CTD PMID:25446015 rotenone multiple interactions ISO RGD:2069 6480464 Rotenone inhibits the reaction [AGT protein results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:10712386 more ... rottlerin multiple interactions ISO RGD:2069 6480464 rottlerin inhibits the reaction [AGT protein affects the localization of ELAVL1 protein] CTD PMID:19246637 rutin multiple interactions ISO RGD:2069 6480464 Rutin inhibits the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:24117263 salubrinal multiple interactions ISO RGD:2069 6480464 salubrinal inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] more ... CTD PMID:25398788 saralasin multiple interactions ISO RGD:2069 6480464 Saralasin inhibits the reaction [AGT protein affects the localization of Calcium], Saralasin inhibits the reaction [AGT protein results in increased activity of SERPINE1 protein] CTD PMID:11244025 , PMID:21613610 SB 203580 decreases response to substance ISO RGD:10118 6480464 SB 203580 results in decreased susceptibility to AGT protein modified form CTD PMID:21289285 SB 203580 multiple interactions ISO RGD:10118 6480464 SB 203580 inhibits the reaction [AGT protein modified form results in decreased susceptibility to Acetylcholine] more ... CTD PMID:21289285 SB 203580 multiple interactions ISO RGD:2069 6480464 SB 203580 inhibits the reaction [AGT protein inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]] more ... CTD PMID:12130563 more ... scopolamine multiple interactions EXP 6480464 [AGT protein modified form binds to and results in decreased activity of LNPEP protein] which results in decreased susceptibility to Scopolamine CTD PMID:11707427 sildenafil citrate increases expression EXP 6480464 Sildenafil Citrate results in increased expression of AGT protein modified form CTD PMID:15613622 sildenafil citrate multiple interactions ISO RGD:10118 6480464 PRKG1 protein promotes the reaction [Sildenafil Citrate inhibits the reaction [AGT protein modified form results in increased expression of CCN2 mRNA]] more ... CTD PMID:25139994 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of AGT mRNA CTD PMID:25895662 silicon dioxide multiple interactions ISO RGD:2069 6480464 AGT protein modified form inhibits the reaction [Silicon Dioxide results in decreased expression of GLI3 protein] more ... CTD PMID:31181250 silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of AGT mRNA CTD PMID:23806026 silver atom decreases expression ISO RGD:2069 6480464 Silver results in decreased expression of AGT mRNA CTD PMID:26277626 silver(0) decreases expression ISO RGD:2069 6480464 Silver results in decreased expression of AGT mRNA CTD PMID:26277626 silver(1+) decreases expression ISO RGD:2069 6480464 Silver results in decreased expression of AGT mRNA CTD PMID:26277626 simvastatin multiple interactions EXP 6480464 [Valsartan co-treated with Simvastatin] inhibits the reaction [AGT protein results in increased expression of KLF10 mRNA] more ... CTD PMID:17513949 , PMID:19225232 simvastatin multiple interactions ISO RGD:2069 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]] more ... CTD PMID:18400235 more ... simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of AGT mRNA CTD PMID:18475152 sirolimus multiple interactions ISO RGD:2069 6480464 Sirolimus inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of AGT mRNA CTD PMID:28973481 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of AGT mRNA CTD PMID:29301061 sodium arsenite multiple interactions ISO RGD:2069 6480464 candesartan cilexetil inhibits the reaction [sodium arsenite results in increased expression of AGT protein modified form] CTD PMID:27889505 sodium arsenite increases response to substance EXP 6480464 AGT protein modified form results in increased susceptibility to sodium arsenite CTD PMID:27889505 sodium arsenite increases expression ISO RGD:10118 6480464 sodium arsenite results in increased expression of AGT protein CTD PMID:22750630 sodium arsenite increases expression ISO RGD:2069 6480464 sodium arsenite results in increased expression of AGT protein modified form CTD PMID:26079204 , PMID:27889505 sodium arsenite multiple interactions EXP 6480464 ERN1 affects the reaction [sodium arsenite results in increased expression of AGT mRNA] more ... CTD PMID:28973481 sodium atom multiple interactions ISO RGD:2069 6480464 acetovanillone inhibits the reaction [AGT protein results in decreased export of Sodium] more ... CTD PMID:14597645 sodium atom decreases abundance EXP 6480464 AGT protein results in decreased abundance of Sodium CTD PMID:12869368 sodium atom increases expression ISO RGD:2069 6480464 Sodium deficiency results in increased expression of AGT protein CTD PMID:3028957 sodium atom decreases export ISO RGD:2069 6480464 AGT protein results in decreased export of Sodium CTD PMID:14597645 sodium chloride multiple interactions EXP 6480464 [Enalapril co-treated with Sodium Chloride] results in increased susceptibility to AGT protein modified form, ACE gene polymorphism inhibits the reaction [[Enalapril co-treated with Sodium Chloride] results in increased susceptibility to AGT protein modified form] CTD PMID:20829712 sodium chloride increases expression ISO RGD:2069 6480464 Sodium Chloride results in increased expression of AGT protein CTD PMID:20232302 sodium chloride multiple interactions ISO RGD:2069 6480464 [AGT protein co-treated with Sodium Chloride] affects the expression of ALOX5 mRNA more ... CTD PMID:15809360 more ... Soman decreases expression ISO RGD:2069 6480464 Soman results in decreased expression of AGT mRNA CTD PMID:19281266 spironolactone decreases expression ISO RGD:2069 6480464 Spironolactone results in decreased expression of AGT protein modified form CTD PMID:19114643 spironolactone multiple interactions ISO RGD:2069 6480464 Dactinomycin promotes the reaction [Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]], Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA] CTD PMID:23288202 spironolactone increases expression EXP 6480464 Spironolactone results in increased expression of AGT protein modified form CTD PMID:7357812 , PMID:9595286 streptozocin multiple interactions ISO RGD:10118 6480464 IGF1 protein inhibits the reaction [Streptozocin results in increased expression of AGT protein] CTD PMID:11375343 streptozocin increases expression ISO RGD:10118 6480464 Streptozocin results in increased expression of AGT mRNA, Streptozocin results in increased expression of AGT protein CTD PMID:11375343 more ... streptozocin increases expression ISO RGD:2069 6480464 Streptozocin results in increased expression of AGT mRNA more ... CTD PMID:15643138 more ... streptozocin multiple interactions ISO RGD:2069 6480464 ACE2 inhibits the reaction [Streptozocin results in increased expression of AGT protein modified form] more ... CTD PMID:20547220 more ... succimer multiple interactions EXP 6480464 [Succimer co-treated with Magnetite Nanoparticles] results in decreased expression of AGT mRNA CTD PMID:26378955 sucrose multiple interactions ISO RGD:2069 6480464 Sucrose inhibits the reaction [[AGT protein binds to and results in increased localization of AGTR1A protein] which results in increased expression of PTGS2 protein], Sucrose inhibits the reaction [AGT protein binds to and results in increased localization of AGTR1A protein] CTD PMID:18267125 sulforaphane multiple interactions ISO RGD:10118 6480464 NFE2L2 gene mutant form inhibits the reaction [sulforafan inhibits the reaction [AGT protein modified form results in increased expression of CTGF protein]] more ... CTD PMID:29353218 superoxide multiple interactions ISO RGD:10118 6480464 1 more ... CTD PMID:12606818 more ... superoxide multiple interactions EXP 6480464 SOD1 protein inhibits the reaction [AGT protein modified form results in increased abundance of Superoxides] CTD PMID:24363997 superoxide increases abundance ISO RGD:10118 6480464 AGT protein modified form results in increased abundance of Superoxides, AGT protein results in increased abundance of Superoxides CTD PMID:12606818 more ... superoxide increases abundance ISO RGD:2069 6480464 AGT protein modified form results in increased abundance of Superoxides, AGT protein results in increased abundance of Superoxides CTD PMID:16531806 more ... superoxide multiple interactions ISO RGD:2069 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:16531806 , PMID:18250367 tamibarotene multiple interactions ISO RGD:10118 6480464 tamibarotene inhibits the reaction [AGT protein results in increased expression of IL6 mRNA], tamibarotene inhibits the reaction [AGT protein results in increased secretion of IL6 protein] CTD PMID:16484594 tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of AGT mRNA CTD PMID:14699072 taurine multiple interactions ISO RGD:2069 6480464 Taurine inhibits the reaction [Glucose results in increased expression of AGT mRNA], Taurine inhibits the reaction [Glucose results in increased expression of AGT protein] CTD PMID:12130563 taurolithocholic acid sulfate multiple interactions ISO RGD:2069 6480464 AGT protein inhibits the reaction [taurolithocholic acid 3-sulfate results in increased activity of CASP3 protein] CTD PMID:23300732 taurolithocholic acid sulfate decreases response to substance ISO RGD:2069 6480464 AGT protein results in decreased susceptibility to taurolithocholic acid 3-sulfate CTD PMID:23300732 tauroursodeoxycholic acid decreases expression ISO RGD:2069 6480464 tauroursodeoxycholic acid results in decreased expression of AGT mRNA CTD PMID:15885361 tauroursodeoxycholic acid multiple interactions ISO RGD:2069 6480464 tauroursodeoxycholic acid inhibits the reaction [AGT protein promotes the reaction [SREBF1 protein binds to TGFB1 promoter]] more ... CTD PMID:25398788 telmisartan multiple interactions ISO RGD:10118 6480464 telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA], telmisartan inhibits the reaction [AGT protein results in increased expression of IL6 protein] CTD PMID:17620961 , PMID:19289654 telmisartan decreases expression ISO RGD:2069 6480464 telmisartan results in decreased expression of AGT mRNA, telmisartan results in decreased expression of AGT protein CTD PMID:19171132 , PMID:9533614 telmisartan multiple interactions ISO RGD:2069 6480464 telmisartan inhibits the reaction [AGT protein results in decreased expression of PLAU mRNA] more ... CTD PMID:18487452 more ... temozolomide decreases response to substance EXP 6480464 AGT protein mutant form results in decreased susceptibility to temozolomide, AGT protein results in decreased susceptibility to temozolomide CTD PMID:11034089 testosterone multiple interactions ISO RGD:2069 6480464 Testosterone affects the reaction [Sodium Chloride, Dietary results in increased expression of AGT mRNA], Testosterone affects the reaction [Sodium Chloride, Dietary results in increased expression of AGT protein] CTD PMID:19211690 Testosterone propionate increases expression ISO RGD:2069 6480464 Testosterone Propionate results in increased expression of AGT mRNA CTD PMID:1568764 tetrachloromethane multiple interactions ISO RGD:2069 6480464 IL10 protein inhibits the reaction [Carbon Tetrachloride results in increased expression of AGT protein] CTD PMID:12632514 tetrachloromethane increases expression ISO RGD:2069 6480464 Carbon Tetrachloride results in increased expression of AGT protein CTD PMID:12632514 tetracycline decreases expression ISO RGD:10118 6480464 Tetracycline results in decreased expression of AGT mRNA CTD PMID:24489787 thioacetamide affects expression ISO RGD:2069 6480464 Thioacetamide affects the expression of AGT mRNA CTD PMID:19483382 thioacetamide multiple interactions ISO RGD:2069 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in decreased expression of AGT mRNA CTD PMID:28943392 thioacetamide decreases expression ISO RGD:2069 6480464 Thioacetamide results in decreased expression of AGT mRNA CTD PMID:23411599 thiopental increases expression EXP 6480464 Thiopental results in increased expression of AGT protein CTD PMID:6349867 Tiron multiple interactions EXP 6480464 1 more ... CTD PMID:15677497 Tiron multiple interactions ISO RGD:2069 6480464 1 more ... CTD PMID:12130563 Tiron multiple interactions ISO RGD:10118 6480464 1 more ... CTD PMID:17391658 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of AGT protein CTD PMID:22352400 titanium dioxide multiple interactions ISO RGD:10118 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of AGT mRNA CTD PMID:29950665 titanium dioxide decreases expression ISO RGD:2069 6480464 titanium dioxide results in decreased expression of AGT mRNA, titanium dioxide results in decreased expression of AGT protein CTD PMID:26277626 titanium dioxide decreases expression ISO RGD:10118 6480464 titanium dioxide results in decreased expression of AGT mRNA CTD PMID:23557971 trandolapril decreases expression ISO RGD:2069 6480464 trandolapril results in decreased expression of AGT protein modified form CTD PMID:27428043 trandolapril multiple interactions ISO RGD:2069 6480464 trandolapril inhibits the reaction [Isoproterenol results in increased expression of AGT protein] CTD PMID:1534315 trandolapril multiple interactions ISO RGD:10118 6480464 trandolapril inhibits the reaction [REN2 protein results in increased expression of AGT protein modified form] CTD PMID:27428043 trans-piceid multiple interactions ISO RGD:2069 6480464 polydatin inhibits the reaction [AGT protein modified form results in increased expression of CYBB mRNA] more ... CTD PMID:25488910 tributylstannane increases expression ISO RGD:10118 6480464 tributyltin results in increased expression of AGT mRNA CTD PMID:23428407 tributylstannane decreases expression ISO RGD:2069 6480464 tributyltin results in decreased expression of AGT protein modified form CTD PMID:30172001 trichloroethene decreases expression ISO RGD:2069 6480464 Trichloroethylene results in decreased expression of AGT mRNA CTD PMID:17905399 , PMID:19448997 triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of AGT mRNA CTD PMID:30510588 troglitazone multiple interactions EXP 6480464 troglitazone inhibits the reaction [AGT protein modified form results in decreased secretion of Nitric Oxide], troglitazone inhibits the reaction [AGT protein modified form results in increased expression of EDN1 protein] CTD PMID:17666345 tyrphostin AG 1478 multiple interactions ISO RGD:2069 6480464 RTKI cpd inhibits the reaction [AGT protein promotes the reaction [SP1 protein binds to TGFB1 promoter]] more ... CTD PMID:15849355 , PMID:25398788 U-73122 multiple interactions ISO RGD:2069 6480464 1-(6-((3-methoxyestra-1 more ... CTD PMID:18250367 , PMID:21613610 valproic acid affects expression ISO RGD:10118 6480464 Valproic Acid affects the expression of AGT mRNA CTD PMID:17292431 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of AGT mRNA CTD PMID:23527032 more ... valsartan multiple interactions EXP 6480464 [benazepril co-treated with Valsartan] results in decreased expression of AGT protein modified form more ... CTD PMID:11244025 more ... valsartan increases expression ISO RGD:2069 6480464 Valsartan results in increased expression of AGT protein, Valsartan results in increased expression of AGT protein modified form CTD PMID:11501062 , PMID:15831366 valsartan multiple interactions ISO RGD:10118 6480464 [Valsartan co-treated with AGT protein] results in increased activity of LPL protein more ... CTD PMID:16769992 more ... valsartan increases expression EXP 6480464 Valsartan results in increased expression of AGT protein, Valsartan results in increased expression of AGT protein modified form CTD PMID:10082498 more ... valsartan multiple interactions ISO RGD:2069 6480464 Dactinomycin promotes the reaction [Valsartan inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]] more ... CTD PMID:11115077 more ... Vinpocetine multiple interactions ISO RGD:2069 6480464 vinpocetine inhibits the reaction [AGT protein inhibits the reaction [NPPA protein results in increased abundance of Cyclic GMP]] CTD PMID:11696475 vismodegib multiple interactions EXP 6480464 HhAntag691 inhibits the reaction [AGT protein results in decreased expression of GLI3 protein] more ... CTD PMID:31181250 vitamin E multiple interactions ISO RGD:10118 6480464 alpha-Tocopherol inhibits the reaction [AGT protein results in increased expression of PSMC6 protein], alpha-Tocopherol inhibits the reaction [AGT protein results in increased phosphorylation of NFKBIA protein] CTD PMID:17532611 wortmannin multiple interactions ISO RGD:2069 6480464 Wortmannin inhibits the reaction [AGT protein results in increased cleavage of SREBF1 protein] more ... CTD PMID:15121739 more ... xestospongin C multiple interactions ISO RGD:2069 6480464 xestospongin C inhibits the reaction [AGT protein affects the localization of Calcium] CTD PMID:21613610 zaragozic acid A affects expression ISO RGD:2069 6480464 squalestatin 1 affects the expression of AGT mRNA CTD PMID:27225895 zaragozic acid A decreases expression ISO RGD:10118 6480464 squalestatin 1 results in decreased expression of AGT mRNA CTD PMID:27225895 zinc atom increases localization ISO RGD:2069 6480464 AGT protein results in increased localization of Zinc CTD PMID:22427991 zinc atom affects binding EXP 6480464 AGT protein binds to Zinc CTD PMID:23896426 zinc atom multiple interactions ISO RGD:2069 6480464 N more ... CTD PMID:22427991 zinc protoporphyrin multiple interactions EXP 6480464 [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK1 protein]], [zinc protoporphyrin results in decreased activity of HMOX1 protein] inhibits the reaction [neferine inhibits the reaction [AGT protein results in increased phosphorylation of MAPK3 protein]] CTD PMID:20523338 zinc(0) increases localization ISO RGD:2069 6480464 AGT protein results in increased localization of Zinc CTD PMID:22427991 zinc(0) multiple interactions ISO RGD:2069 6480464 N more ... CTD PMID:22427991 zinc(0) affects binding EXP 6480464 AGT protein binds to Zinc CTD PMID:23896426
Gene-Chemical Interaction Annotations
