GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | AGT | increases expression | ISO | Agt (Mus musculus) | 6480464 | CTD | Tretinoin results in increased expression of AGT mRNA | PMID:16505366 | AGT | multiple interactions | ISO | Agt (Mus musculus) | 6480464 | CTD | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of AGT mRNA; AGN 193109 inhibits the reaction [Tretinoin results in increased expression of AGT mRNA] | PMID:16505366 PMID:36189433 | AGT | multiple interactions | ISO | Agt (Rattus norvegicus) | 6480464 | CTD | Tretinoin inhibits the reaction [AGT protein results in increased expression of TGFB1 protein]; Tretinoin inhibits the reaction [AGT protein results in increased secretion of COL3A1 protein] | PMID:16539842 | | ||||||||||||||||||||||
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