AGT (angiotensinogen) - Rat Genome Database

Name: AGT
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| FTP Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes QTLs Strains Markers Genome Information Ontologies Cell Lines References FTP Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) RatMine GViewer (Genome Viewer) Overgo Probe Designer ACP Haplotyper Genome Scanner Aging & Age-Related Disease Cancer Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models PhenoMiner (Quantitative Phenotypes) Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: AGT (angiotensinogen) Sus scrofa

Analyze

Symbol:

AGT

Name:

angiotensinogen

RGD ID:

14230380

Description:

ENCODES a protein that exhibits hormone activity (ortholog); receptor ligand activity (ortholog); sodium channel regulator activity (ortholog); INVOLVED IN activation of MAPK activity (ortholog); activation of NF-kappaB-inducing kinase activity (ortholog); activation of phospholipase C activity (ortholog); PARTICIPATES IN angiotensin (1-7) signaling pathway; angiotensin II signaling pathway; angiotensin II signaling pathway via AT1 receptor; ASSOCIATED WITH abdominal aortic aneurysm (ortholog); Albuminuria (ortholog); alcoholic cardiomyopathy (ortholog); FOUND IN cytoplasm (ortholog); INTERACTS WITH aldosterone; clofibrate; cortisol

Type:

protein-coding

RefSeq Status:

MODEL

Also known as:

angiotensinogen (serpin peptidase inhibitor, clade A, member 8); serpin peptidase inhibitor, clade A, member 8

RGD Orthologs

Human

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	AGT (angiotensinogen)	HGNC	EggNOG, Ensembl, NCBI, OrthoDB, Panther
Mus musculus (house mouse):	Agt (angiotensinogen (serpin peptidase inhibitor, clade A, member 8))	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus norvegicus (Norway rat):	Agt (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Agt (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	AGT (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	AGT (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Agt (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):	AGT (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Agt (angiotensinogen)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	59,643,292 - 59,672,428 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	59,643,030 - 59,656,835 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	64,380,799 - 64,385,995 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

abdominal aortic aneurysm (ISO)

Albuminuria (ISO)

alcoholic cardiomyopathy (ISO)

alcoholic hepatitis (ISO)

Alkalosis (ISO)

Allanson Pantzar McLeod Syndrome (ISO)

allergic disease (ISO)

Alzheimer's disease (ISO)

Anaphylaxis (ISO)

anemia (ISO)

anti-basement membrane glomerulonephritis (ISO)

anuria (ISO)

aortic aneurysm (ISO)

Aortic Calcification (ISO)

Aortic Coarctation (ISO)

atherosclerosis (ISO)

atrial fibrillation (ISO)

Bradycardia (ISO)

breast cancer (ISO)

Cardiac Arrhythmias (ISO)

Cardiomegaly (ISO)

cardiomyopathy (ISO)

Cardiovascular Abnormalities (ISO)

cardiovascular system disease (ISO)

carotid artery disease (ISO)

Catalepsy (ISO)

cerebrovascular disease (ISO)

Chemical and Drug Induced Liver Injury (ISO)

cholestasis (ISO)

Chronic Intermittent Hypoxia (ISO)

chronic myeloid leukemia (ISO)

cognitive disorder (ISO)

congestive heart failure (ISO)

corneal neovascularization (ISO)

Crohn's disease (ISO)

Diabetic Cardiomyopathies (ISO)

Diabetic Nephropathies (ISO)

diabetic retinopathy (ISO)

Diaphragmatic Hernia (ISO)

diffuse scleroderma (ISO)

dilated cardiomyopathy (ISO)

Dissecting Aneurysm (ISO)

Drug Overdose (ISO)

endomyocardial fibrosis (ISO)

essential hypertension (ISO)

Experimental Diabetes Mellitus (ISO)

Experimental Liver Cirrhosis (ISO)

Fabry disease (ISO)

Fetal Growth Retardation (ISO)

Fibrosis (ISO)

focal segmental glomerulosclerosis (ISO)

gastric ulcer (ISO)

glomerulonephritis (ISO)

glucose intolerance (ISO)

heart disease (ISO)

Hemorrhage (ISO)

Henoch-Schoenlein purpura (ISO)

hydronephrosis (ISO)

Hyperalgesia (ISO)

Hyperemia (ISO)

hyperhomocysteinemia (ISO)

hyperinsulinism (ISO)

hypertension (ISO)

Hypertensive Nephropathy (ISO)

hypertrophic cardiomyopathy (ISO)

Hypertrophy (ISO)

hypokalemia (ISO)

Hypotension (ISO)

IgA glomerulonephritis (ISO)

impotence (ISO)

Inflammation (ISO)

inflammatory bowel disease (ISO)

intermediate coronary syndrome (ISO)

Intestinal Reperfusion Injury (ISO)

kidney disease (ISO)

kidney failure (ISO)

Left Ventricular Hypertrophy (ISO)

liver cirrhosis (ISO)

malignant hypertension (ISO)

Mammary Neoplasms, Experimental (ISO)

meconium aspiration syndrome (ISO)

Metabolic Syndrome (ISO)

microcephaly (ISO)

middle cerebral artery infarction (ISO)

mitral valve prolapse (ISO)

multiple sclerosis (ISO)

myocardial infarction (ISO)

Myocardial Ischemia (ISO)

Myocardial Reperfusion Injury (ISO)

Necrosis (ISO)

Neointima (ISO)

nephrosis (ISO)

Neurobehavioral Manifestations (ISO)

obesity (ISO)

otosclerosis (ISO)

Peptic Ulcer Hemorrhage (ISO)

pneumonia (ISO)

polycystic kidney disease (ISO)

pre-eclampsia (ISO)

prediabetes syndrome (ISO)

Pregnancy-Induced Hypertension (ISO)

primary biliary cholangitis (ISO)

proteinuria (ISO)

pulmonary edema (ISO)

pulmonary fibrosis (ISO)

pulmonary hypertension (ISO)

Puromycin Aminonucleoside Nephrosis (ISO)

renal hypertension (ISO)

Renal Tubular Dysgenesis (ISO)

Reperfusion Injury (ISO)

retinal vasculitis (ISO)

retinopathy of prematurity (ISO)

sciatic neuropathy (ISO)

sick sinus syndrome (ISO)

skin melanoma (ISO)

Stroke (ISO)

Sudden Death (ISO)

systemic scleroderma (ISO)

temporal lobe epilepsy (ISO)

thrombosis (ISO)

transient cerebral ischemia (ISO)

type 2 diabetes mellitus (ISO)

ureteral obstruction (ISO)

Vascular Remodeling (ISO)

Ventricular Dysfunction, Left (ISO)

Ventricular Remodeling (ISO)

visual epilepsy (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

aldosterone (EXP)

clofibrate (EXP)

cortisol (EXP)

DPDPE (EXP)

enalapril (EXP)

enalaprilat dihydrate (EXP)

indometacin (EXP)

losartan (EXP)

nitric oxide (EXP)

progesterone (EXP)

Tanshinone I (EXP)

U50488 (EXP)

valsartan (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of MAPK activity (ISO)

activation of NF-kappaB-inducing kinase activity (ISO)

activation of phospholipase C activity (ISO)

aging (ISO)

angiotensin-activated signaling pathway (ISO)

angiotensin-mediated drinking behavior (ISO)

angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (ISO)

artery smooth muscle contraction (ISO)

associative learning (ISO)

astrocyte activation (ISO)

blood vessel development (ISO)

brain renin-angiotensin system (ISO)

branching involved in ureteric bud morphogenesis (ISO)

cell growth involved in cardiac muscle cell development (ISO)

cell surface receptor signaling pathway (ISO)

cell-matrix adhesion (ISO)

cellular response to angiotensin (ISO)

cellular response to mechanical stimulus (ISO)

cellular sodium ion homeostasis (ISO)

cytokine production (ISO)

drinking behavior (ISO)

ERK1 and ERK2 cascade (ISO)

establishment of blood-nerve barrier (ISO)

excretion (ISO)

extracellular matrix organization (ISO)

female pregnancy (ISO)

fibroblast proliferation (ISO)

G protein-coupled receptor signaling pathway (ISO)

hormone metabolic process (ISO)

kidney development (ISO)

negative regulation of angiogenesis (ISO)

negative regulation of cell growth (ISO)

negative regulation of cell population proliferation (ISO)

negative regulation of endopeptidase activity (IBA)

negative regulation of gene expression (ISO)

negative regulation of MAP kinase activity (ISO)

negative regulation of neuron apoptotic process (ISO)

negative regulation of neurotrophin TRK receptor signaling pathway (ISO)

negative regulation of tissue remodeling (ISO)

obsolete positive regulation of blood vessel diameter (ISO)

operant conditioning (ISO)

ovarian follicle rupture (ISO)

peristalsis (ISO)

positive regulation of activation of Janus kinase activity (ISO)

positive regulation of blood pressure (ISO)

positive regulation of branching involved in ureteric bud morphogenesis (ISO)

positive regulation of cardiac muscle cell apoptotic process (ISO)

positive regulation of cardiac muscle hypertrophy (ISO)

positive regulation of catalytic activity (ISO)

positive regulation of cell population proliferation (ISO)

positive regulation of cellular protein metabolic process (ISO)

positive regulation of cholesterol esterification (ISO)

positive regulation of cytokine production (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of endothelial cell migration (ISO)

positive regulation of epidermal growth factor receptor signaling pathway (ISO)

positive regulation of extracellular matrix constituent secretion (ISO)

positive regulation of extrinsic apoptotic signaling pathway (ISO)

positive regulation of fatty acid biosynthetic process (ISO)

positive regulation of fibroblast proliferation (ISO)

positive regulation of gap junction assembly (ISO)

positive regulation of gene expression (ISO)

positive regulation of insulin receptor signaling pathway (ISO)

positive regulation of L-arginine import across plasma membrane (ISO)

positive regulation of L-lysine import across plasma membrane (ISO)

positive regulation of MAPK cascade (ISO)

positive regulation of membrane hyperpolarization (ISO)

positive regulation of multicellular organism growth (ISO)

positive regulation of neuron projection development (ISO)

positive regulation of nitric oxide biosynthetic process (ISO)

positive regulation of organ growth (ISO)

positive regulation of peptidyl-serine phosphorylation (ISO)

positive regulation of peptidyl-tyrosine phosphorylation (ISO)

positive regulation of phosphatidylinositol 3-kinase signaling (ISO)

positive regulation of protein kinase C activity (ISO)

positive regulation of protein tyrosine kinase activity (ISO)

positive regulation of renal sodium excretion (ISO)

positive regulation of superoxide anion generation (ISO)

positive regulation of transcription, DNA-templated (ISO)

positive regulation of vascular associated smooth muscle cell migration (ISO)

positive regulation of vascular associated smooth muscle cell proliferation (ISO)

protein import into nucleus (ISO)

regulation of apoptotic process (ISO)

regulation of blood pressure (ISO)

regulation of calcium ion transport (ISO)

regulation of cardiac conduction (ISO)

regulation of extracellular matrix assembly (ISO)

regulation of gene expression (ISO)

regulation of heart rate (ISO)

regulation of inflammatory response (ISO)

regulation of long-term neuronal synaptic plasticity (ISO)

regulation of norepinephrine secretion (ISO)

regulation of renal output by angiotensin (ISO)

regulation of renal sodium excretion (ISO)

regulation of systemic arterial blood pressure by circulatory renin-angiotensin (ISO)

regulation of systemic arterial blood pressure by renin-angiotensin (IEA)

regulation of transmission of nerve impulse (ISO)

renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure (ISO)

renal system process (ISO)

renin-angiotensin regulation of aldosterone production (ISO)

response to cold (ISO)

response to estradiol (ISO)

response to muscle activity involved in regulation of muscle adaptation (ISO)

response to salt stress (ISO)

smooth muscle cell differentiation (ISO)

smooth muscle cell proliferation (ISO)

stress-activated MAPK cascade (ISO)

uterine smooth muscle contraction (ISO)

vasoconstriction (IEA)

vasodilation (ISO)

Cellular Component

cytoplasm (ISO)

extracellular space (IBA,IEA)

mitochondrion (ISO)

Molecular Function

hormone activity (ISO)

protein binding (ISO)

receptor ligand activity (ISO)

serine-type endopeptidase inhibitor activity (IBA)

sodium channel regulator activity (ISO)

type 1 angiotensin receptor binding (ISO)

type 2 angiotensin receptor binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

angiotensin (1-7) signaling pathway (ISO)

angiotensin II signaling pathway (ISO)

angiotensin II signaling pathway via AT1 receptor (ISO)

angiotensin II signaling pathway via AT2 receptor (ISO)

angiotensin III signaling pathway (ISO)

angiotensin III signaling pathway via AT1 receptor (ISO)

angiotensin III signaling pathway via AT2 receptor (ISO)

angiotensin IV signaling pathway (ISO)

angiotensin signaling pathway (ISO)

benazepril pharmacodynamics pathway (ISO)

candesartan pharmacodynamics pathway (ISO)

captopril pharmacodynamics pathway (ISO)

cilazapril pharmacodynamics pathway (ISO)

enalapril pharmacodynamics pathway (ISO)

eprosartan pharmacodynamics pathway (ISO)

forasartsn pharmacodynamics pathway (ISO)

fosinopril pharmacodynamics pathway (ISO)

irbesartan pharmacodynamics pathway (ISO)

lisinopril pharmacodynamics pathway (ISO)

long term potentiation (ISO)

losartan pharmacodynamics pathway (ISO)

moexipril pharmacodynamics pathway (ISO)

myocardial infarction pathway (ISO)

olmesartan pharmacodynamics pathway (ISO)

perindopril pharmacodynamics pathway (ISO)

quinapril pharmacodynamics pathway (ISO)

ramipril pharmacodynamics pathway (ISO)

renin-angiotensin cascade pathway (ISO)

spirapril pharmacodynamics pathway (ISO)

telmisartan pharmacodynamics pathway (ISO)

trandolapril pharmacodynamics pathway (ISO)

valsartan pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:14681463	PMID:16390332	PMID:17145712	PMID:18310517	PMID:18331442	PMID:27443965

Genomics

Comparative Map Data

AGT
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	59,643,292 - 59,672,428 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	59,643,030 - 59,656,835 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	64,380,799 - 64,385,995 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

AGT
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	230,702,523 - 230,714,122 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	230,702,523 - 230,745,583 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	230,838,269 - 230,850,336 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	228,904,892 - 228,916,564 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	227,145,019 - 227,156,602	NCBI
Celera	1	204,104,291 - 204,116,358 (-)	NCBI
Cytogenetic Map	1	q42.2	NCBI
HuRef	1	201,323,209 - 201,335,277 (-)	NCBI		HuRef
CHM1_1	1	232,111,282 - 232,123,349 (-)	NCBI		CHM1_1

Agt
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	125,283,326 - 125,296,445 (-)	NCBI	GRCm39		mm39
GRCm38	8	124,556,587 - 124,569,706 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	124,556,534 - 124,569,706 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	127,080,487 - 127,093,607 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	8	127,442,677 - 127,455,773 (-)	NCBI			mm8
Celera	8	128,860,995 - 128,873,954 (-)	NCBI		Celera
Cytogenetic Map	8	E2	NCBI
cM Map	8	72.81	NCBI

Agt
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	19	57,321,594 - 57,333,460 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	19	57,321,640 - 57,333,433 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	19	68,026,182 - 68,038,550 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	19	54,738,556 - 54,750,349 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	19	54,743,436 - 54,755,230 (-)	NCBI
Celera	19	51,899,180 - 51,910,819 (-)	NCBI		Celera
Cytogenetic Map	19	q12	NCBI

Agt
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955492	7,866,833 - 7,873,357 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955492	7,863,662 - 7,874,863 (+)	NCBI	ChiLan1.0	ChiLan1.0

AGT
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	211,279,015 - 211,291,044 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	211,279,015 - 211,291,044 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	206,252,141 - 206,263,830 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

AGT
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	4	8,683,798 - 8,693,880 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	4	8,681,192 - 8,694,059 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Agt
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936484	19,713,299 - 19,721,144 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

AGT
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1 Ensembl	25	67,962,401 - 67,973,324 (-)	Ensembl
ChlSab1.1	25	67,964,840 - 67,977,006 (-)	NCBI

Agt
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624775	18,846,222 - 18,856,093 (+)	NCBI

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	hemolymphoid system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium		1				19
Low	10	3	3	4	2	4	1	1
Below cutoff				1			1	2	3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_021073990	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000096	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK232926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK391972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK399866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01116031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSSSCT00000011150 ⟹ ENSSSCP00000010861

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	59,643,300 - 59,672,428 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000036625 ⟹ ENSSSCP00000029872

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	59,648,471 - 59,672,428 (+)	Ensembl

RefSeq Acc Id:

ENSSSCT00000050329 ⟹ ENSSSCP00000044037

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	14	59,643,292 - 59,653,040 (+)	Ensembl

RefSeq Acc Id:

XM_021073990 ⟹ XP_020929649

RefSeq Status:

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	14	59,643,030 - 59,656,835 (+)	NCBI

Sequence:

show sequence

GTCAATGTGTAACTCAGCTGTGTACCAGCTCCCTCTGTTCAGCAGCAGCAGCGTGCATTGCATC
GATCCCGCTTCCTGGAAGGAGCCCAGCGTGAGTTGCCTGGCGCCTGTCCCCCTCGTGGGCCGGC
TGCCTGAGGCCCCCACCCCCTCGGCCCAGCCAAGTGATGCAACCCTTCCCACCGCCTGGGCACA
GGACGGCCTGGGAACGGCTCCATCCCCTCCCTTCAGACATAAATAGGCCTCGGTGGCCAGTGGC
CTGGCCAGGAAAGAGGCCACCCTTGTCTCAGACGAGAGCTTAAGGGTCGCAAGAGTGAACCCCA
TCAGAGATGGCTCCTGCTGGCCTGAGCCTCGGCGCCACTGTCCTCGGCCTCTTGGCCTGGGCCA
GCCTGGCCGCCGGGGACCGGGTTTATATACACCCCTTCCACCTCCTCGTCTACAGCAAGAGCAG
CTGTGAGCAGCTGGAGAAAACTGGGGCAGAGACCCCCGCAGACCCGACATTCGCGCCTGTCCCC
ATTCAGGCCAAGTCGTCCCCCGTGGACGAGGAGGCCCTGCGGGAAGCGCTGGTTCAAGCCACCG
AGGGGCTGGAGGCCGAGGACCGGCTGAGGGCTGCGAAAGTGGGGATGCTGCTCAATTTCATGGG
CTTCCACATGTACAAGACGCTGAGCGCCACATGGAGCGTGGCCGGCGGGGCTGTGTTCTCCCCG
GTGGCTCTCTTTGGCACACTGACCTCCTTCTACCTGGGCGCCTCAGACCCCACGGCCAGAAGAC
TACAGGCCTTCCTGGGCGTCCCTGGGGAGGATCAGGGCTGCACCTCCCGGCTGGACGGTCACAA
GGTCCTGTCTGCCCTGCAGACCATCCAGGGCCTTCTGGTCACCCAGGGTGGGGCCGGCAGCCAG
GCCAGGCTGCTCCTATCCACAGTGGTCGGCCTGTTCACGGCCCCCGGGCTGCGCCTGAAGCAGC
GGTTCGTGCAGGACCTGGCTCCCTTCGCCGTCACCCTCCCACGCTCCCTAGACCTGTCCTCAGA
CCCAGATCTCGCTGCTGAGAAGATCAACAGGTTCATGCAGGCGGTGACAGGGTGGAAGATGGGC
ACGCCGCTGAGAGGGGTCAGCCCAGACAGCACCCTACTCCTCAATACCTACGTGCACTTCCAAG
GAAAGGTGAAGGGCTTCTCCCTGCTGCCGGGGCTCCAGGAGTTCCGGGTGGACAACACCACCTC
AGTGTCGGTCCCCATGCTCTCGGGCACTGGTACCTTCCACTACTGGAGCGACGACCAGAACAAC
CTCTCAGTGATCCGCGTGCCCCTCAGCGCCCATGCCAGCCTGCTGCTCATCCAGCCACACACCT
TCGACCTGCACAAGGTCGAGGCCCTCACCTTCCAGCACAACTTCCTGACCTGGACCAAGAACCT
GTCTCCCCGGGCCATCCGCCTGACAATGCCCCAGCTGACACTGCAAGGGTCCTATGACCTGCAG
GACCTGCTGGCCCAGACCAAGCTGCCCACGCTGCTAGGTGCTGAGGCAAACCTGCGCAAAATCA
GTGATGATGACCTCAGGGTTGGAAAGGTGCTGAACAGCGTCCTTTTTGAGCTCAAAGCAGACGA
GGGAGAGCAGCCCACGGAGTCCGCCCTGCAGCCGGCCGGGCCCGAGGCCTTGGAGGTGACGCTG
AACAGCCCATTCCTATTGGCCGTCTTGGAGCGAGAATCAGCTGCCCTGACCTTCCTGGGCCGTG
TGGCCAACCCCATAAGTGCCGCCTGAGGCTTGGCCCTGGCATCACCAGGGCCACCAGCGTGCCA
CCACCAGTCACCACCCATCTCCATTCTCTTCCATGGAGTCTGCCTAGAGCCAAGAGCGGCGCTG
CTCTGAGAACCATGCTGTGTACAAAGGGTGGCAGCCCAGGGCAGGTGCCGGGCAGAGCCGAGTC
TGGCACAGACCCCGTTCCCCAAAGAGCTTGAACACACCGGCTTATTGGTGAAACCTGAAACACA
TTCCCTTTTCACTGAGAACAGGCATTGGGCTTTAAAACAAAAACATCCATTTTCTTTCATTGCC
CCAGACTCACCTATGGCTTATTGAGTATGGCGACCTGCAGGAAACCACAGTGCCTTCCTTTCTC
TAAATTTCTTGGTATTTCTTTCCCCTGATACTTGTGGTTTTTGAAAAACACATCATGAAAACAC
AAGCCTGTGAATGTATGTTAGACCGTAATCCTGCGGCTGGTTATCCCTGTGTTATTAATAAATG
TCTTGCAACAATAAACAAAAAGGAAACACTC

hide sequence

Protein Sequences


Protein RefSeqs	XP_020929649	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

XP_020929649 ⟸ XM_021073990

- Sequence:

show sequence

MAPAGLSLGATVLGLLAWASLAAGDRVYIHPFHLLVYSKSSCEQLEKTGAETPADPTFAPVPIQ
AKSSPVDEEALREALVQATEGLEAEDRLRAAKVGMLLNFMGFHMYKTLSATWSVAGGAVFSPVA
LFGTLTSFYLGASDPTARRLQAFLGVPGEDQGCTSRLDGHKVLSALQTIQGLLVTQGGAGSQAR
LLLSTVVGLFTAPGLRLKQRFVQDLAPFAVTLPRSLDLSSDPDLAAEKINRFMQAVTGWKMGTP
LRGVSPDSTLLLNTYVHFQGKVKGFSLLPGLQEFRVDNTTSVSVPMLSGTGTFHYWSDDQNNLS
VIRVPLSAHASLLLIQPHTFDLHKVEALTFQHNFLTWTKNLSPRAIRLTMPQLTLQGSYDLQDL
LAQTKLPTLLGAEANLRKISDDDLRVGKVLNSVLFELKADEGEQPTESALQPAGPEALEVTLNS
PFLLAVLERESAALTFLGRVANPISAA

hide sequence

RefSeq Acc Id:

ENSSSCP00000044037 ⟸ ENSSSCT00000050329

RefSeq Acc Id:

ENSSSCP00000010861 ⟸ ENSSSCT00000011150

RefSeq Acc Id:

ENSSSCP00000029872 ⟸ ENSSSCT00000036625

Protein Domains

SERPIN

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000010184	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00070015511	UniProtKB/TrEMBL
Ensembl Protein	ENSSSCP00000010861	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCP00000029872	UniProtKB/TrEMBL
	ENSSSCP00000044037	UniProtKB/TrEMBL
	ENSSSCP00070025388	UniProtKB/TrEMBL
	ENSSSCP00070025395	UniProtKB/TrEMBL
	ENSSSCP00070025400	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000011150	ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCT00000036625	UniProtKB/TrEMBL
	ENSSSCT00000050329	UniProtKB/TrEMBL
	ENSSSCT00070030443	UniProtKB/TrEMBL
	ENSSSCT00070030451	UniProtKB/TrEMBL
	ENSSSCT00070030455	UniProtKB/TrEMBL
Gene3D-CATH	2.30.39.10	UniProtKB/TrEMBL
	3.30.497.10	UniProtKB/TrEMBL
InterPro	Angiotensinogen	UniProtKB/TrEMBL
	Serpin_CS	UniProtKB/TrEMBL
	Serpin_dom	UniProtKB/TrEMBL
	Serpin_fam	UniProtKB/TrEMBL
	Serpin_sf	UniProtKB/TrEMBL
	Serpin_sf_1	UniProtKB/TrEMBL
	Serpin_sf_2	UniProtKB/TrEMBL
NCBI Gene	AGT	ENTREZGENE
PANTHER	PTHR11461	UniProtKB/TrEMBL
	PTHR11461:SF13	UniProtKB/TrEMBL
Pfam	Serpin	UniProtKB/TrEMBL
PRINTS	ANGIOTENSNGN	UniProtKB/TrEMBL
PROSITE	SERPIN	UniProtKB/TrEMBL
SMART	SERPIN	UniProtKB/TrEMBL
Superfamily-SCOP	SSF56574	UniProtKB/TrEMBL
UniGene	Ssc.54070	ENTREZGENE
	Ssc.89585	ENTREZGENE
UniProt	A0A287AJ51_PIG	UniProtKB/TrEMBL
	A0A4X1UAY5_PIG	UniProtKB/TrEMBL
	A0A5K1UCV8_PIG	UniProtKB/TrEMBL
	F1RG45_PIG	UniProtKB/TrEMBL
UniProt Secondary	K7GPQ7	UniProtKB/TrEMBL
VGNC ID	VGNC:85190	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - SMPDB