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Gene: IMPA1 (inositol monophosphatase 1) Homo sapiens
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Symbol: IMPA1
Name: inositol monophosphatase 1
Description: Exhibits inositol monophosphate 1-phosphatase activity; metal ion binding activity; and protein homodimerization activity. Involved in inositol phosphate dephosphorylation; phosphatidylinositol biosynthetic process; and signal transduction. Localizes to the cytoplasm. Implicated in autosomal recessive non-syndromic intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D-galactose 1-phosphate phosphatase; IMP; IMP 1; IMPA; IMPase 1; inositol (myo)-1(or 4)-monophosphatase 1; inositol(myo)-1(or 4)-monophosphatase 1; inositol-1(or 4)-monophosphatase 1; lithium-sensitive myo-inositol monophosphatase A1; MRT59; myo-inositol monophosphatase 1; testicular tissue protein Li 94
Orthologs:
Mus musculus (house mouse) : Impa1 (inositol (myo)-1(or 4)-monophosphatase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Impa1 (inositol monophosphatase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Impa1 (inositol monophosphatase 1)
Canis lupus familiaris (dog) : IMPA1 (inositol monophosphatase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Impa1 (inositol monophosphatase 1)
Sus scrofa (pig) : IMPA1 (inositol monophosphatase 1)
Chlorocebus sabaeus (green monkey) : IMPA1 (inositol monophosphatase 1)
Heterocephalus glaber (naked mole-rat) : Impa1 (inositol monophosphatase 1)
more info ...
Related Pseudogenes: IMPA1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl881,656,914 - 81,686,331 (-)Ensembl
GRCh38881,656,914 - 81,686,354 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37882,569,151 - 82,599,029 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36882,732,751 - 82,761,115 (-)NCBINCBI36hg18NCBI36
Build 34882,732,750 - 82,761,115NCBI
Celera878,574,122 - 78,603,090 (-)NCBI
Cytogenetic Map8q21.13NCBI
HuRef878,058,964 - 78,088,484 (-)NCBIHuRef
CHM1_1882,620,772 - 82,650,210 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on IMPA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 737559
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.