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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:serpentine asbestos
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Accession:CHEBI:46680 term browser browse the term
Synonyms:related_synonym: White asbestos
 xref: CAS:132207-32-0
 xref_mesh: MESH:D017632


show annotations for term's descendants           Sort by:
serpentine asbestos term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aatk apoptosis-associated tyrosine kinase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of AATK promoter CTD PMID:29626692 NCBI chr10:105,290,752...105,327,219
Ensembl chr10:105,291,585...105,327,112 		JBrowse link
G Abr ABR activator of RhoGEF and GTPase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ABR promoter CTD PMID:29626692 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505 		JBrowse link
G Acsbg1 acyl-CoA synthetase bubblegum family member 1 increases expression ISO Asbestos, Serpentine results in increased expression of ACSBG1 mRNA CTD PMID:23917077 NCBI chr 8:54,991,294...55,047,276
Ensembl chr 8:54,991,296...55,047,391 		JBrowse link
G Acta2 actin alpha 2, smooth muscle multiple interactions
increases expression
decreases expression		 ISO TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of ACTA2 protein]
Asbestos, Serpentine results in increased expression of ACTA2 mRNA; Asbestos, Serpentine results in increased expression of ACTA2 protein
Asbestos, Serpentine results in decreased expression of ACTA2 mRNA		 CTD PMID:24160326 PMID:26685284 PMID:29523930 PMID:30609805 NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actb actin, beta increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of ACTB mRNA
Asbestos, Serpentine results in increased expression of and results in increased phosphorylation of ACTB protein		 CTD PMID:23706555 NCBI chr12:11,663,112...11,666,697
Ensembl chr12:11,663,109...11,672,877 		JBrowse link
G Actg2 actin gamma 2, smooth muscle decreases expression ISO Asbestos, Serpentine results in decreased expression of ACTG2 mRNA CTD PMID:29523930 NCBI chr 4:116,021,832...116,046,475
Ensembl chr 4:116,021,832...116,046,465 		JBrowse link
G Actn2 actinin alpha 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of ACTN2 5' UTR CTD PMID:29523930 NCBI chr17:58,143,334...58,210,622
Ensembl chr17:58,142,625...58,210,622 		JBrowse link
G Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of ADAMTS2 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of ADAMTS2 mRNA]		 CTD PMID:21514415 NCBI chr10:34,920,992...35,126,465
Ensembl chr10:34,921,049...35,123,821 		JBrowse link
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 increases expression ISO Asbestos, Serpentine results in increased expression of ADAMTS5 mRNA CTD PMID:24160326 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 increases expression ISO Asbestos, Serpentine results in increased expression of ADAMTS9 mRNA CTD PMID:24160326 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Adarb2 adenosine deaminase RNA specific B2 increases methylation ISO Asbestos, Serpentine results in increased methylation of ADARB2 gene CTD PMID:29523930 NCBI chr17:61,750,437...62,300,984
Ensembl chr17:61,756,067...62,300,831 		JBrowse link
G Adcyap1r1 ADCYAP receptor type I decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ADCYAP1R1 5' UTR CTD PMID:29523930 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700 		JBrowse link
G Adgrg1 adhesion G protein-coupled receptor G1 decreases expression ISO Asbestos, Serpentine results in decreased expression of ADGRG1 mRNA CTD PMID:21148743 NCBI chr19:10,003,963...10,041,122
Ensembl chr19:10,003,975...10,041,108 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO Asbestos, Serpentine results in decreased expression of ADIPOQ mRNA CTD PMID:23917077 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adm adrenomedullin increases expression ISO Asbestos, Serpentine results in increased expression of ADM mRNA CTD PMID:29523930 NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654 		JBrowse link
G Aff3 ALF transcription elongation factor 3 increases expression ISO Asbestos, Serpentine results in increased expression of AFF3 mRNA CTD PMID:21148743 NCBI chr 9:40,399,099...40,856,716
Ensembl chr 9:40,404,375...40,857,247 		JBrowse link
G Agr2 anterior gradient 2, protein disulphide isomerase family member increases expression ISO Asbestos, Serpentine results in increased expression of AGR2 mRNA CTD PMID:16251409 NCBI chr 6:52,708,602...52,729,378
Ensembl chr 6:52,708,602...52,729,371 		JBrowse link
G Akap12 A-kinase anchoring protein 12 increases expression ISO Asbestos, Serpentine results in increased expression of AKAP12 mRNA CTD PMID:21148743 PMID:29523930 NCBI chr 1:40,730,123...40,819,863
Ensembl chr 1:40,730,123...40,819,886 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Asbestos, Serpentine results in increased phosphorylation of AKT1 protein CTD PMID:26685284 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alpk2 alpha-kinase 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of ALPK2 mRNA CTD PMID:29523930 NCBI chr18:58,775,603...58,906,150
Ensembl chr18:58,775,605...58,906,258 		JBrowse link
G Ambra1 autophagy and beclin 1 regulator 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of AMBRA1 gene CTD PMID:29523930 NCBI chr 3:77,700,936...77,890,221
Ensembl chr 3:77,700,936...77,890,221 		JBrowse link
G Amigo2 adhesion molecule with Ig like domain 2 affects expression
decreases methylation		 ISO Asbestos, Serpentine affects the expression of AMIGO2 mRNA
Asbestos, Serpentine results in decreased methylation of AMIGO2 5' UTR		 CTD PMID:24160326 PMID:29523930 NCBI chr 7:128,391,493...128,394,589
Ensembl chr 7:128,390,412...128,394,695 		JBrowse link
G Angptl4 angiopoietin-like 4 increases expression ISO Asbestos, Serpentine results in increased expression of ANGPTL4 mRNA CTD PMID:29523930 NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519 		JBrowse link
G Ankdd1a ankyrin repeat and death domain containing 1A decreases expression ISO Asbestos, Serpentine results in decreased expression of ANKDD1A mRNA CTD PMID:21148743 NCBI chr 8:66,017,571...66,043,738
Ensembl chr 8:66,017,773...66,042,651 		JBrowse link
G Ankrd11 ankyrin repeat domain containing 11 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ANKRD11 promoter CTD PMID:29626692 NCBI chr19:50,940,284...51,098,962
Ensembl chr19:50,940,299...51,098,962 		JBrowse link
G Ankrd52 ankyrin repeat domain 52 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ANKRD52 promoter CTD PMID:29626692 NCBI chr 7:806,829...820,481
Ensembl chr 7:806,767...820,481 		JBrowse link
G Ankrd53 ankyrin repeat domain 53 increases methylation ISO Asbestos, Serpentine results in increased methylation of ANKRD53 5' UTR CTD PMID:29523930 NCBI chr 4:116,245,561...116,253,018
Ensembl chr 4:116,246,955...116,253,017 		JBrowse link
G Anp32a acidic nuclear phosphoprotein 32 family member A increases methylation ISO Asbestos, Serpentine results in increased methylation of ANP32A gene CTD PMID:29523930 NCBI chr 8:62,829,099...62,865,443
Ensembl chr 8:62,827,456...62,865,443 		JBrowse link
G Anpep alanyl aminopeptidase, membrane increases expression ISO Asbestos, Serpentine results in increased expression of ANPEP mRNA CTD PMID:24160326 NCBI chr 1:133,767,332...133,810,137
Ensembl chr 1:133,767,332...133,785,789 		JBrowse link
G Anxa8 annexin A8 decreases expression ISO Asbestos, Serpentine results in decreased expression of ANXA8 mRNA CTD PMID:29523930 NCBI chr16:9,397,144...9,412,072
Ensembl chr16:9,397,113...9,412,043 		JBrowse link
G Apoc1 apolipoprotein C1 decreases expression ISO Asbestos, Serpentine results in decreased expression of APOC1 mRNA CTD PMID:21148743 NCBI chr 1:79,347,057...79,350,340
Ensembl chr 1:79,346,136...79,350,375 		JBrowse link
G Aqp9 aquaporin 9 increases expression ISO Asbestos, Serpentine results in increased expression of AQP9 mRNA CTD PMID:24160326 NCBI chr 8:71,797,231...71,837,485
Ensembl chr 8:71,797,234...71,837,395 		JBrowse link
G Areg amphiregulin increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of AREG mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of AREG mRNA]		 CTD PMID:21514415 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arfgap3 ARF GTPase activating protein 3 affects expression ISO Asbestos, Serpentine affects the expression of ARFGAP3 mRNA CTD PMID:24160326 NCBI chr 7:114,432,873...114,479,206
Ensembl chr 7:114,432,873...114,479,208 		JBrowse link
G Arhgap21 Rho GTPase activating protein 21 increases methylation ISO Asbestos, Serpentine results in increased methylation of ARHGAP21 5' UTR CTD PMID:29523930 NCBI chr17:83,348,673...83,472,202
Ensembl chr17:83,348,673...83,472,444 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ARHGAP42 5' UTR CTD PMID:29523930 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Arhgef17 Rho guanine nucleotide exchange factor 17 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ARHGEF17 promoter CTD PMID:29626692 NCBI chr 1:155,230,607...155,290,163
Ensembl chr 1:155,233,168...155,290,498 		JBrowse link
G Arhgef4 Rho guanine nucleotide exchange factor 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ARHGEF4 promoter CTD PMID:29626692 NCBI chr 9:36,861,800...37,005,079
Ensembl chr 9:36,861,835...37,005,075 		JBrowse link
G Ascl2 achaete-scute family bHLH transcription factor 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ASCL2 3' UTR CTD PMID:29523930 NCBI chr 1:198,148,999...198,151,406
Ensembl chr 1:198,148,999...198,151,406 		JBrowse link
G Asrgl1 asparaginase and isoaspartyl peptidase 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of ASRGL1 mRNA CTD PMID:21148743 NCBI chr 1:206,006,103...206,027,115
Ensembl chr 1:206,006,109...206,027,108 		JBrowse link
G Atf3 activating transcription factor 3 increases expression ISO Asbestos, Serpentine results in increased expression of ATF3 mRNA CTD PMID:18197826 NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO Asbestos, Serpentine results in increased expression of ATF6 protein CTD PMID:25324550 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Atl3 atlastin GTPase 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of ATL3 mRNA CTD PMID:24160326 NCBI chr 1:204,680,958...204,727,360
Ensembl chr 1:204,680,968...204,723,354 		JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 increases expression ISO Asbestos, Serpentine results in increased expression of ATP2B1 mRNA CTD PMID:24160326 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295 		JBrowse link
G Aurkc aurora kinase C decreases methylation ISO Asbestos, Serpentine results in decreased methylation of AURKC promoter CTD PMID:29626692 NCBI chr 1:66,843,653...66,849,775
Ensembl chr 1:66,843,653...66,864,386 		JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Asbestos, Serpentine results in increased expression of AXL mRNA CTD PMID:29523930 NCBI chr 1:81,265,088...81,296,278
Ensembl chr 1:81,265,088...81,296,265 		JBrowse link
G B3gnt5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 increases expression ISO Asbestos, Serpentine results in increased expression of B3GNT5 mRNA CTD PMID:24160326 NCBI chr11:81,141,102...81,153,206
Ensembl chr11:81,140,599...81,156,166 		JBrowse link
G Barx1 BARX homeobox 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of BARX1 promoter CTD PMID:29626692 NCBI chr17:15,990,412...15,993,887
Ensembl chr17:15,990,412...15,993,887 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Asbestos, Serpentine results in increased expression of BAX CTD PMID:15882436 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bbs12 Bardet-Biedl syndrome 12 affects methylation ISO Asbestos, Serpentine affects the methylation of BBS12 5' UTR CTD PMID:29523930 NCBI chr 2:120,203,396...120,221,024
Ensembl chr 2:120,203,428...120,219,255 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member decreases expression ISO Asbestos, Serpentine results in decreased expression of BCAR3 mRNA CTD PMID:21148743 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bcas3 BCAS3, microtubule associated cell migration factor decreases methylation ISO Asbestos, Serpentine results in decreased methylation of BCAS3 gene CTD PMID:29523930 NCBI chr10:70,213,710...70,673,080
Ensembl chr10:70,214,098...70,673,080 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
affects response to substance		 ISO [Asbestos, Serpentine results in decreased susceptibility to Asbestos, Serpentine] which results in increased expression of BCL2 mRNA; [Asbestos, Serpentine results in decreased susceptibility to Asbestos, Serpentine] which results in increased expression of BCL2 protein
BCL2 protein affects the susceptibility to Asbestos, Serpentine		 CTD PMID:16850164 PMID:22608188 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l11 Bcl2-like 11 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of BCL2L11 protein
PRKD1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]; U 0126 promotes the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]		 CTD PMID:19116364 NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase increases expression ISO Asbestos, Serpentine results in increased expression of BCR mRNA CTD PMID:21148743 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Bdkrb1 bradykinin receptor B1 decreases expression ISO Asbestos, Serpentine results in decreased expression of BDKRB1 mRNA CTD PMID:24160326 NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747 		JBrowse link
G Begain brain-enriched guanylate kinase-associated increases expression ISO Asbestos, Serpentine results in increased expression of BEGAIN mRNA CTD PMID:29523930 NCBI chr 6:127,943,651...127,979,876
Ensembl chr 6:127,943,651...127,979,841 		JBrowse link
G Bhlhe41 basic helix-loop-helix family, member e41 decreases expression ISO Asbestos, Serpentine results in decreased expression of BHLHE41 mRNA CTD PMID:24160326 NCBI chr 4:178,834,264...178,838,618
Ensembl chr 4:178,834,271...178,838,468 		JBrowse link
G Bmp6 bone morphogenetic protein 6 decreases expression ISO Asbestos, Serpentine results in decreased expression of BMP6 mRNA CTD PMID:16251409 NCBI chr17:26,318,121...26,469,691
Ensembl chr17:26,318,569...26,470,365 		JBrowse link
G Boc BOC cell adhesion associated, oncogene regulated decreases methylation ISO Asbestos, Serpentine results in decreased methylation of BOC gene CTD PMID:29523930 NCBI chr11:56,122,697...56,198,060
Ensembl chr11:56,122,750...56,198,059 		JBrowse link
G Bpifa1 BPI fold containing family A, member 1 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of BPIFA1 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of BPIFA1 mRNA]		 CTD PMID:21514415 NCBI chr 3:142,627,810...142,633,553
Ensembl chr 3:142,627,810...142,633,552 		JBrowse link
G Bst2 bone marrow stromal cell antigen 2 increases expression ISO Asbestos, Serpentine results in increased expression of BST2 mRNA CTD PMID:24160326 NCBI chr16:18,216,605...18,220,979
Ensembl chr16:18,217,407...18,220,979 		JBrowse link
G C13h1orf226 similar to human chromosome 1 open reading frame 226 decreases expression ISO Asbestos, Serpentine results in decreased expression of C1ORF226 mRNA CTD PMID:21148743 NCBI chr13:82,530,589...82,538,676
Ensembl chr13:82,530,577...82,820,949 		JBrowse link
G C3 complement C3 increases expression ISO Asbestos, Serpentine results in increased expression of C3 mRNA CTD PMID:24160326 NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G C5 complement C5 multiple interactions
increases cleavage		 ISO 1,3-dimethylthiourea inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein]; [Egtazic Acid co-treated with Asbestos, Serpentine] results in increased cleavage of C5 protein; [Ethylene Glycol co-treated with Asbestos, Serpentine] results in increased cleavage of C5 protein; Ascorbic Acid inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein]; Deferoxamine inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein]; Dithionite inhibits the reaction [Asbestos, Serpentine results in increased cleavage of C5 protein] CTD PMID:10777245 NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994 		JBrowse link
G C8h19orf38 similar to human chromosome 19 open reading frame 38 decreases expression ISO Asbestos, Serpentine results in decreased expression of C19ORF38 mRNA CTD PMID:21148743 NCBI chr 8:20,061,494...20,095,705
Ensembl chr 8:20,078,639...20,095,696 		JBrowse link
G Cab39l calcium binding protein 39-like increases expression ISO Asbestos, Serpentine results in increased expression of CAB39L mRNA CTD PMID:21148743 NCBI chr15:33,606,588...33,710,518
Ensembl chr15:33,606,694...33,743,545 		JBrowse link
G Cabp7 calcium binding protein 7 increases expression ISO Asbestos, Serpentine results in increased expression of CABP7 mRNA CTD PMID:21148743 NCBI chr14:79,598,822...79,609,172
Ensembl chr14:79,598,827...79,609,240 		JBrowse link
G Cacng8 calcium voltage-gated channel auxiliary subunit gamma 8 increases methylation ISO Asbestos, Serpentine results in increased methylation of CACNG8 5' UTR CTD PMID:29523930 NCBI chr 1:65,755,334...65,775,567
Ensembl chr 1:65,755,334...65,779,089 		JBrowse link
G Calm3 calmodulin 3 increases expression ISO Asbestos, Serpentine results in increased expression of CALM3 mRNA CTD PMID:16251409 NCBI chr 1:77,590,668...77,597,776
Ensembl chr 1:77,589,230...77,592,207 		JBrowse link
G Camk4 calcium/calmodulin-dependent protein kinase IV decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CAMK4 promoter CTD PMID:29626692 NCBI chr18:24,582,988...24,811,918
Ensembl chr18:24,585,269...24,802,487 		JBrowse link
G Cap2 cyclase associated actin cytoskeleton regulatory protein 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CAP2 3' UTR CTD PMID:29523930 NCBI chr17:18,054,234...18,203,453
Ensembl chr17:18,054,431...18,203,373 		JBrowse link
G Car2 carbonic anhydrase 2 increases expression ISO Asbestos, Serpentine results in increased expression of CA2 mRNA CTD PMID:21148743 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Car9 carbonic anhydrase 9 increases expression ISO Asbestos, Serpentine results in increased expression of CA9 mRNA CTD PMID:29523930 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838 		JBrowse link
G Cask calcium/calmodulin dependent serine protein kinase decreases expression ISO Asbestos, Serpentine results in decreased expression of CASK mRNA CTD PMID:21148743 NCBI chr  X:8,899,500...9,243,014
Ensembl chr  X:8,899,833...9,238,694 		JBrowse link
G Caskin2 cask-interacting protein 2 increases expression ISO Asbestos, Serpentine results in increased expression of CASKIN2 mRNA CTD PMID:21148743 NCBI chr10:101,027,196...101,041,429
Ensembl chr10:101,027,260...101,041,414 		JBrowse link
G Casp1 caspase 1 increases activity
increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased activity of CASP1 protein
Asbestos, Serpentine results in increased expression of CASP1 protein modified form
tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Asbestos, Serpentine results in increased expression of CASP1 protein modified form]		 CTD PMID:23017228 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383 		JBrowse link
G Casp3 caspase 3 increases cleavage
increases activity		 ISO
EXP		 Asbestos, Serpentine results in increased cleavage of CASP3 protein
Asbestos, Serpentine results in increased activity of CASP3 protein		 CTD PMID:18300051 PMID:22608188 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 increases cleavage
increases expression		 ISO
EXP		 Asbestos, Serpentine results in increased cleavage of CASP9 protein
Asbestos, Serpentine results in increased expression of CASP9 protein		 CTD PMID:18300051 PMID:24735948 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Ccdc141 coiled-coil domain containing 141 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CCDC141 5' UTR CTD PMID:29523930 NCBI chr 3:61,948,614...62,109,968
Ensembl chr 3:61,948,646...62,110,079 		JBrowse link
G Ccdc149 coiled-coil domain containing 149 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CCDC149 3' UTR; Asbestos, Serpentine results in decreased methylation of CCDC149 gene CTD PMID:29523930 NCBI chr14:58,509,583...58,605,017
Ensembl chr14:58,509,811...58,604,696 		JBrowse link
G Ccdc66 coiled-coil domain containing 66 increases expression ISO Asbestos, Serpentine results in increased expression of CCDC66 mRNA CTD PMID:21148743 NCBI chr16:2,662,125...2,694,031
Ensembl chr16:2,662,131...2,694,023 		JBrowse link
G Ccdc88a coiled coil domain containing 88A increases expression ISO Asbestos, Serpentine results in increased expression of CCDC88A mRNA CTD PMID:21148743 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases secretion
decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased secretion of CCL11 protein
Asbestos, Serpentine results in decreased expression of CCL11 protein
SPP1 gene mutant form promotes the reaction [Asbestos, Serpentine results in decreased expression of CCL11 protein]		 CTD PMID:21514415 PMID:23017228 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression ISO Asbestos, Serpentine results in increased expression of CCL12 mRNA CTD PMID:16251409 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion		 ISO
EXP		 Asbestos, Serpentine results in increased expression of CCL2 mRNA
Asbestos, Serpentine results in increased expression of CCL2 mRNA; Asbestos, Serpentine results in increased expression of CCL2 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL2 protein]
IL1B protein promotes the reaction [Asbestos, Serpentine results in increased expression of CCL2 mRNA]; IL1B protein promotes the reaction [Asbestos, Serpentine results in increased secretion of CCL2 protein]; TNF protein promotes the reaction [Asbestos, Serpentine results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Asbestos, Serpentine results in increased secretion of CCL2 protein]		 CTD PMID:10923243 PMID:17200189 PMID:21514415 PMID:23917077 PMID:24160326 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl20 C-C motif chemokine ligand 20 increases expression ISO Asbestos, Serpentine results in increased expression of CCL20 mRNA CTD PMID:24160326 NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 multiple interactions
increases expression		 ISO PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL3 protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CCL3 protein] CTD PMID:17200189 PMID:21514415 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression
increases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of CCL4 mRNA
Asbestos, Serpentine results in increased expression of CCL4 protein
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CCL4 protein]		 CTD PMID:17200189 PMID:21148743 PMID:21514415 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of CCL5 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL5 protein]		 CTD PMID:17200189 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Asbestos, Serpentine results in increased expression of CCL6 mRNA CTD PMID:16251409 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of CCN2
TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of CCN2]		 CTD PMID:19817698 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccnb2 cyclin B2 increases expression ISO Asbestos, Serpentine results in increased expression of CCNB2 mRNA CTD PMID:16251409 NCBI chr 8:71,087,594...71,100,794
Ensembl chr 8:71,087,595...71,100,874 		JBrowse link
G Ccnd1 cyclin D1 multiple interactions ISO [MPO protein affects the susceptibility to Asbestos, Serpentine] which affects the expression of CCND1 protein CTD PMID:16266986 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 increases expression ISO Asbestos, Serpentine results in increased expression of CCR2 mRNA CTD PMID:16251409 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Cd164 CD164 molecule decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CD164 gene CTD PMID:29523930 NCBI chr20:45,024,051...45,035,628
Ensembl chr20:45,023,973...45,035,634 		JBrowse link
G Cd209d CD209d molecule decreases expression ISO Asbestos, Serpentine results in decreased expression of CD209 mRNA CTD PMID:24160326 NCBI chr12:1,891,109...1,897,559
Ensembl chr12:1,891,113...1,901,171 		JBrowse link
G Cd244 CD244 molecule decreases expression ISO Asbestos, Serpentine results in decreased expression of CD244 protein CTD PMID:19822075 NCBI chr13:84,051,339...84,082,864
Ensembl chr13:84,052,493...84,074,492 		JBrowse link
G Cd36 CD36 molecule decreases expression ISO Asbestos, Serpentine results in decreased expression of CD36 mRNA CTD PMID:24160326 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd44 CD44 molecule increases expression ISO Asbestos, Serpentine results in increased expression of CD44 mRNA CTD PMID:21514415 PMID:29523930 PMID:33581214 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd59b CD59b molecule increases mutagenesis ISO Asbestos, Serpentine results in increased mutagenesis of CD59 protein CTD PMID:17045307 NCBI chr 3:90,459,085...90,477,571
Ensembl chr 3:90,459,162...90,478,847 		JBrowse link
G Cd68 Cd68 molecule increases expression ISO Asbestos, Serpentine results in increased expression of CD68 mRNA CTD PMID:29523930 NCBI chr10:54,381,814...54,383,693
Ensembl chr10:54,381,815...54,383,697 		JBrowse link
G Cd79b CD79b molecule increases expression ISO Asbestos, Serpentine results in increased expression of CD79B mRNA CTD PMID:29523930 NCBI chr10:91,239,354...91,242,500
Ensembl chr10:91,239,356...91,242,625 		JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Asbestos, Serpentine results in increased expression of CDC20 mRNA CTD PMID:16251409 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdcp1 CUB domain containing protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of CDCP1 mRNA CTD PMID:29523930 NCBI chr 8:122,828,685...122,865,345
Ensembl chr 8:122,828,685...122,865,388 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression		 ISO 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one analog inhibits the reaction [Asbestos, Serpentine results in decreased expression of CDH1 protein]; SB 216763 inhibits the reaction [Asbestos, Serpentine results in decreased expression of CDH1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of CDH1 protein]
Asbestos, Serpentine results in decreased expression of CDH1 mRNA; Asbestos, Serpentine results in decreased expression of CDH1 protein		 CTD PMID:24160326 PMID:26685284 PMID:30609805 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh13 cadherin 13 increases expression ISO Asbestos, Serpentine results in increased expression of CDH13 mRNA CTD PMID:24160326 NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459 		JBrowse link
G Cdhr1 cadherin-related family member 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CDHR1 gene CTD PMID:29523930 NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396 		JBrowse link
G Cdk18 cyclin-dependent kinase 18 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CDK18 promoter CTD PMID:29626692 NCBI chr13:43,555,597...43,582,210
Ensembl chr13:43,556,748...43,588,525 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B decreases expression ISO Asbestos, Serpentine results in decreased expression of CDKN1B mRNA CTD PMID:16251409 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
G Cdkn1c cyclin-dependent kinase inhibitor 1C decreases expression ISO Asbestos, Serpentine results in decreased expression of CDKN1C mRNA CTD PMID:29523930 NCBI chr 1:198,655,394...198,658,097
Ensembl chr 1:198,655,407...198,658,048 		JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A decreases expression EXP Asbestos, Serpentine results in decreased expression of CDKN2A mRNA; Asbestos, Serpentine results in decreased expression of CDKN2A protein CTD PMID:32755622 NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149 		JBrowse link
G Cdo1 cysteine dioxygenase type 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of CDO1 mRNA CTD PMID:16251409 NCBI chr18:39,432,473...39,447,253
Ensembl chr18:39,432,474...39,447,296 		JBrowse link
G Cdx2 caudal type homeo box 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CDX2 promoter CTD PMID:29626692 NCBI chr12:7,726,798...7,733,142
Ensembl chr12:7,726,798...7,733,142 		JBrowse link
G Cemip cell migration inducing hyaluronidase 1 increases expression ISO Asbestos, Serpentine results in increased expression of CEMIP mRNA CTD PMID:29523930 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415 		JBrowse link
G Cenpj centromere protein J increases methylation ISO Asbestos, Serpentine results in increased methylation of CPAP gene CTD PMID:29523930 NCBI chr15:30,627,206...30,690,384
Ensembl chr15:30,627,224...30,686,791 		JBrowse link
G Cep112 centrosomal protein 112 increases methylation ISO Asbestos, Serpentine results in increased methylation of CEP112 5' UTR CTD PMID:29523930 NCBI chr10:93,366,059...93,833,133
Ensembl chr10:93,366,136...93,833,131 		JBrowse link
G Ces3a carboxylesterase 3a decreases expression ISO Asbestos, Serpentine results in decreased expression of CES3 mRNA CTD PMID:16251409 NCBI chr19:32,992,386...33,000,562 JBrowse link
G Cgas cyclic GMP-AMP synthase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CGAS gene CTD PMID:29523930 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Ch25h cholesterol 25-hydroxylase increases expression ISO Asbestos, Serpentine results in increased expression of CH25H mRNA CTD PMID:16251409 NCBI chr 1:232,014,877...232,016,195
Ensembl chr 1:232,014,880...232,016,195 		JBrowse link
G Chl1 cell adhesion molecule L1-like increases methylation ISO Asbestos, Serpentine results in increased methylation of CHL1 gene CTD PMID:29523930 NCBI chr 4:136,291,504...136,505,830
Ensembl chr 4:136,291,463...136,503,265 		JBrowse link
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 increases expression ISO Asbestos, Serpentine results in increased expression of CITED1 mRNA CTD PMID:18197826 NCBI chr  X:67,350,376...67,355,072
Ensembl chr  X:67,350,373...67,355,162 		JBrowse link
G Ckap2 cytoskeleton associated protein 2 multiple interactions
increases expression		 ISO SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CKAP2 mRNA] CTD PMID:21514415 NCBI chr16:69,839,668...69,864,852
Ensembl chr16:69,839,630...69,864,913 		JBrowse link
G Ckb creatine kinase B decreases expression ISO Asbestos, Serpentine results in decreased expression of CKB mRNA CTD PMID:21148743 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 increases expression ISO Asbestos, Serpentine results in increased expression of CKS2 mRNA CTD PMID:16251409 NCBI chr17:13,570,611...13,575,770 JBrowse link
G Clca1 chloride channel accessory 1 increases expression ISO Asbestos, Serpentine results in increased expression of CLCA1 mRNA; Asbestos, Serpentine results in increased expression of CLCA1 protein CTD PMID:16251409 NCBI chr 2:233,938,677...233,964,369
Ensembl chr 2:233,938,677...233,964,369 		JBrowse link
G Cldn11 claudin 11 increases expression ISO Asbestos, Serpentine results in increased expression of CLDN11 mRNA CTD PMID:24160326 NCBI chr 2:112,207,745...112,221,050
Ensembl chr 2:112,207,745...112,221,050 		JBrowse link
G Cldnd2 claudin domain containing 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CLDND2 5' UTR CTD PMID:29523930 NCBI chr 1:93,848,533...93,851,693
Ensembl chr 1:93,848,533...93,851,217 		JBrowse link
G Clic3 chloride intracellular channel 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of CLIC3 mRNA CTD PMID:29523930 NCBI chr 3:8,271,416...8,274,023
Ensembl chr 3:8,272,097...8,274,018 		JBrowse link
G Clip3 CAP-GLY domain containing linker protein 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of CLIP3 mRNA CTD PMID:29523930 NCBI chr 1:85,547,170...85,563,187
Ensembl chr 1:85,547,206...85,563,184 		JBrowse link
G Cltc clathrin heavy chain decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CLTC gene CTD PMID:29523930 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Cmss1 cms1 ribosomal small subunit homolog affects methylation ISO Asbestos, Serpentine affects the methylation of CMSS1 gene CTD PMID:29523930 NCBI chr11:42,934,390...43,232,624
Ensembl chr11:42,934,440...43,232,624 		JBrowse link
G Cnr1 cannabinoid receptor 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of CNR1 5' UTR CTD PMID:29523930 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col19a1 collagen type XIX alpha 1 chain increases methylation ISO Asbestos, Serpentine results in increased methylation of COL19A1 gene CTD PMID:29523930 NCBI chr 9:26,673,916...27,022,139
Ensembl chr 9:26,675,391...27,022,106 		JBrowse link
G Col1a1 collagen type I alpha 1 chain increases expression ISO Asbestos, Serpentine results in increased expression of COL1A1 mRNA CTD PMID:18039278 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain decreases expression
increases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of COL1A2 mRNA
Asbestos, Serpentine results in increased expression of COL1A2 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of COL1A2 mRNA]		 CTD PMID:16251409 PMID:21514415 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col3a1 collagen type III alpha 1 chain increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of COL3A1 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of COL3A1 mRNA]		 CTD PMID:21514415 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain increases expression ISO Asbestos, Serpentine results in increased expression of COL4A1 mRNA CTD PMID:21514415 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col5a1 collagen type V alpha 1 chain increases expression ISO Asbestos, Serpentine results in increased expression of COL5A1 mRNA CTD PMID:21514415 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Cp ceruloplasmin increases expression ISO Asbestos, Serpentine results in increased expression of CP mRNA CTD PMID:24160326 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Cplx1 complexin 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of CPLX1 5' UTR CTD PMID:29523930 NCBI chr14:1,184,677...1,216,392 JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain decreases expression ISO Asbestos, Serpentine results in decreased expression of CRADD mRNA CTD PMID:21148743 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907 		JBrowse link
G Crisp1 cysteine-rich secretory protein 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of CRISP1 5' UTR CTD PMID:29523930 NCBI chr 9:20,741,775...20,768,796
Ensembl chr 9:20,741,777...20,768,796 		JBrowse link
G Crispld2 cysteine-rich secretory protein LCCL domain containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of CRISPLD2 mRNA CTD PMID:21148743 NCBI chr19:48,053,153...48,111,485
Ensembl chr19:48,053,287...48,110,465 		JBrowse link
G Cryl1 crystallin, lambda 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of CRYL1 gene CTD PMID:29523930 NCBI chr15:31,427,011...31,545,997
Ensembl chr15:31,427,054...31,545,997 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression
increases secretion
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of CSF2 mRNA
[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of CSF2 protein
Asbestos, Serpentine results in increased expression of CSF2 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CSF2 protein]		 CTD PMID:17200189 PMID:23017228 PMID:24160326 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf3 colony stimulating factor 3 increases expression
increases secretion		 ISO Asbestos, Serpentine results in increased expression of CSF3 mRNA
Asbestos, Serpentine results in increased secretion of CSF3 protein
Asbestos, Serpentine results in increased expression of CSF3 protein		 CTD PMID:17200189 PMID:23017228 PMID:24160326 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Csta cystatin A increases expression ISO Asbestos, Serpentine results in increased expression of CSTA mRNA CTD PMID:21148743 NCBI chr11:64,620,483...64,631,488
Ensembl chr11:64,620,483...64,631,488 		JBrowse link
G Ctnnb1 catenin beta 1 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of CTNNB1 mRNA; Asbestos, Serpentine results in decreased expression of CTNNB1 protein
Asbestos, Serpentine results in increased phosphorylation of and affects the localization of CTNNB1 protein; TGFB1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of CTNNB1 protein]; TNF protein promotes the reaction [Asbestos, Serpentine affects the localization of CTNNB1 protein]		 CTD PMID:24160326 PMID:26685284 PMID:30609805 NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111 		JBrowse link
G Ctsk cathepsin K increases expression ISO Asbestos, Serpentine results in increased expression of CTSK mRNA; Asbestos, Serpentine results in increased expression of CTSK protein CTD PMID:16251409 NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550 		JBrowse link
G Ctss cathepsin S increases expression ISO Asbestos, Serpentine results in increased expression of CTSS mRNA CTD PMID:16251409 PMID:24160326 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Ctsz cathepsin Z increases expression ISO Asbestos, Serpentine results in increased expression of CTSZ mRNA CTD PMID:16251409 NCBI chr 3:163,224,875...163,235,645
Ensembl chr 3:163,224,875...163,235,645 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression		 ISO [Asbestos, Serpentine co-treated with 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide] results in increased expression of CXCL1 mRNA
Asbestos, Serpentine results in increased expression of CXCL1 mRNA		 CTD PMID:18197826 PMID:24160326 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 decreases expression
increases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of CXCL10 protein
Asbestos, Serpentine results in increased expression of CXCL10 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CXCL10 mRNA]		 CTD PMID:21148743 PMID:21514415 PMID:24160326 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Asbestos, Serpentine results in increased expression of CXCL12 mRNA CTD PMID:19105532 PMID:24160326 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 increases expression ISO Asbestos, Serpentine results in increased expression of CXCL13 mRNA CTD PMID:33581214 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO Asbestos, Serpentine results in increased expression of CXCL2 mRNA CTD PMID:24160326 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of CXCL1 protein
NLRP3 protein affects the reaction [Asbestos, Serpentine results in increased expression of CXCL1 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CXCL1 protein]
[Asbestos, Serpentine co-treated with 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide] results in increased expression of CXCL1 mRNA
Asbestos, Serpentine results in increased expression of CXCL1 mRNA		 CTD PMID:17200189 PMID:18197826 PMID:18403674 PMID:24160326 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO Asbestos, Serpentine results in increased expression of CXCL6 mRNA CTD PMID:24160326 NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093 		JBrowse link
G Cxcr3 C-X-C motif chemokine receptor 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of CXCR3 mRNA; Asbestos, Serpentine results in decreased expression of CXCR3 protein CTD PMID:21148743 PMID:21357438 NCBI chr  X:66,844,318...66,846,969
Ensembl chr  X:66,844,318...66,846,969 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO Asbestos, Serpentine results in increased expression of CXCR4 mRNA CTD PMID:24160326 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Cxxc5 CXXC finger protein 5 decreases expression ISO Asbestos, Serpentine results in decreased expression of CXXC5 mRNA CTD PMID:21148743 NCBI chr18:27,427,591...27,458,579
Ensembl chr18:27,427,230...27,458,673 		JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CYP11A1 promoter CTD PMID:29626692 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338 		JBrowse link
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of CYP19A1 mRNA CTD PMID:24160326 NCBI chr 8:54,552,978...54,580,375
Ensembl chr 8:54,553,165...54,580,758 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 affects activity ISO Asbestos, Serpentine affects the activity of CYP1A1 protein CTD PMID:12641979 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125 		JBrowse link
G Cyp26c1 cytochrome P450, family 26, subfamily C, polypeptide 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CYP26C1 promoter CTD PMID:29626692 NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842 		JBrowse link
G Cyp27a1 cytochrome P450, family 27, subfamily a, polypeptide 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CYP27A1 promoter CTD PMID:29626692 NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551 		JBrowse link
G Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CYP27B1 promoter CTD PMID:29626692 NCBI chr 7:62,869,340...62,876,242
Ensembl chr 7:62,871,297...62,876,241 		JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of CYP2A4 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of CYP2A4 mRNA]		 CTD PMID:21514415 NCBI chr 1:82,171,914...82,179,980
Ensembl chr 1:82,169,949...82,179,979 		JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 increases methylation ISO Asbestos, Serpentine results in increased methylation of CYP2F1 gene CTD PMID:29523930 NCBI chr 1:82,416,107...82,429,897
Ensembl chr 1:82,416,130...82,429,896 		JBrowse link
G Cyp2w1 cytochrome P450, family 2, subfamily w, polypeptide 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of CYP2W1 promoter CTD PMID:29626692 NCBI chr12:15,291,552...15,296,421
Ensembl chr12:15,291,704...15,296,421 		JBrowse link
G Cytip cytohesin 1 interacting protein increases expression ISO Asbestos, Serpentine results in increased expression of CYTIP mRNA CTD PMID:24160326 NCBI chr 3:42,698,058...42,774,955
Ensembl chr 3:42,698,768...42,725,993 		JBrowse link
G Cytl1 cytokine like 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of CYTL1 mRNA CTD PMID:21514415 NCBI chr14:73,053,876...73,058,886
Ensembl chr14:73,053,877...73,058,886 		JBrowse link
G Dazl deleted in azoospermia-like decreases methylation ISO Asbestos, Serpentine results in decreased methylation of DAZL promoter CTD PMID:29626692 NCBI chr 9:10,695,593...10,712,330
Ensembl chr 9:10,695,592...10,712,323 		JBrowse link
G Dcakd dephospho-CoA kinase domain containing increases methylation ISO Asbestos, Serpentine results in increased methylation of DCAKD 5' UTR CTD PMID:29523930 NCBI chr10:87,957,738...87,989,002
Ensembl chr10:87,957,740...87,980,054 		JBrowse link
G Dchs2 dachsous cadherin-related 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of DCHS2 gene CTD PMID:29523930 NCBI chr 2:168,478,298...168,685,802
Ensembl chr 2:168,478,826...168,682,732 		JBrowse link
G Dclk1 doublecortin-like kinase 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of DCLK1 promoter CTD PMID:29626692 NCBI chr 2:139,417,234...139,710,956
Ensembl chr 2:139,417,163...139,710,956 		JBrowse link
G Dcn decorin increases expression ISO Asbestos, Serpentine results in increased expression of DCN mRNA CTD PMID:24160326 NCBI chr 7:32,281,252...32,321,291
Ensembl chr 7:32,281,252...32,321,270 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression ISO Asbestos, Serpentine results in increased expression of DDIT3 mRNA CTD PMID:25324550 NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Dennd1b DENN domain containing 1B decreases expression ISO Asbestos, Serpentine results in decreased expression of DENND1B mRNA CTD PMID:21148743 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Dennd5a DENN domain containing 5A affects expression ISO Asbestos, Serpentine affects the expression of DENND5A mRNA CTD PMID:24160326 NCBI chr 1:163,928,183...163,994,207
Ensembl chr 1:163,928,183...163,994,316 		JBrowse link
G Dhrs9 dehydrogenase/reductase 9 increases expression ISO Asbestos, Serpentine results in increased expression of DHRS9 mRNA CTD PMID:21148743 NCBI chr 3:54,147,834...54,170,052
Ensembl chr 3:54,147,803...54,220,241 		JBrowse link
G Dio2 iodothyronine deiodinase 2 increases expression ISO Asbestos, Serpentine results in increased expression of DIO2 mRNA CTD PMID:29523930 NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809 		JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 increases expression ISO Asbestos, Serpentine results in increased expression of DKK1 mRNA CTD PMID:29523930 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202 		JBrowse link
G Dmd dystrophin increases expression ISO Asbestos, Serpentine results in increased expression of DMD mRNA CTD PMID:21148743 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Dmpk DM1 protein kinase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of DMPK promoter CTD PMID:29626692 NCBI chr 1:78,730,255...78,740,585
Ensembl chr 1:78,730,275...78,740,593 		JBrowse link
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 increases expression ISO Asbestos, Serpentine results in increased expression of DNAJC3 mRNA CTD PMID:25324550 NCBI chr15:96,025,605...96,068,585
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Dner delta/notch-like EGF repeat containing increases expression ISO Asbestos, Serpentine results in increased expression of DNER mRNA CTD PMID:29523930 NCBI chr 9:85,586,985...85,902,461
Ensembl chr 9:85,586,987...85,902,637 		JBrowse link
G Dpep1 dipeptidase 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of DPEP1 mRNA CTD PMID:16251409 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Drap1 Dr1 associated protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of DRAP1 mRNA CTD PMID:29523930 NCBI chr 1:202,731,775...202,734,468
Ensembl chr 1:202,731,788...202,734,425 		JBrowse link
G Dscam DS cell adhesion molecule decreases methylation ISO Asbestos, Serpentine results in decreased methylation of DSCAM 3' UTR CTD PMID:29523930 NCBI chr11:35,921,924...36,507,100
Ensembl chr11:35,926,896...36,507,415 		JBrowse link
G Dtnbp1 dystrobrevin binding protein 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of DTNBP1 5' UTR CTD PMID:29523930 NCBI chr17:19,685,218...19,776,668
Ensembl chr17:19,685,215...19,776,661 		JBrowse link
G Dusp10 dual specificity phosphatase 10 decreases expression ISO Asbestos, Serpentine results in decreased expression of DUSP10 mRNA CTD PMID:24160326 NCBI chr13:95,613,716...95,651,716
Ensembl chr13:95,614,292...95,651,716 		JBrowse link
G Ece1 endothelin converting enzyme 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ECE1 gene CTD PMID:29523930 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edil3 EGF like repeats and discoidin domains 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of EDIL3 gene CTD PMID:29523930 NCBI chr 2:19,890,396...20,405,028
Ensembl chr 2:19,890,373...20,405,008 		JBrowse link
G Ednrb endothelin receptor type B increases methylation ISO Asbestos, Serpentine results in increased methylation of EDNRB 5' UTR CTD PMID:29523930 NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Efhd1 EF-hand domain family, member D1 decreases expression
decreases methylation		 ISO Asbestos, Serpentine results in decreased expression of EFHD1 mRNA
Asbestos, Serpentine results in decreased methylation of EFHD1 gene		 CTD PMID:29523930 NCBI chr 9:87,938,259...87,984,917
Ensembl chr 9:87,938,284...87,984,917 		JBrowse link
G Efl1 elongation factor like GTPase 1 increases expression ISO Asbestos, Serpentine results in increased expression of EFL1 mRNA CTD PMID:21148743 NCBI chr 1:136,638,527...136,763,518
Ensembl chr 1:136,638,527...136,763,518 		JBrowse link
G Efna3 ephrin A3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of EFNA3 gene CTD PMID:29523930 NCBI chr 2:174,729,192...174,738,111
Ensembl chr 2:174,729,764...174,738,736 		JBrowse link
G Egfr epidermal growth factor receptor decreases phosphorylation
increases activity
multiple interactions		 ISO Asbestos, Serpentine results in decreased phosphorylation of EGFR protein
Asbestos, Serpentine results in increased activity of EGFR protein
N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos, Serpentine results in increased activity of EGFR protein]		 CTD PMID:15626777 PMID:16571779 NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of EGR1 mRNA
clinoptilolite inhibits the reaction [Asbestos, Serpentine results in increased expression of EGR1 mRNA]		 CTD PMID:32123850 NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Ehd1 EH-domain containing 1 affects expression ISO Asbestos, Serpentine affects the expression of EHD1 mRNA CTD PMID:24160326 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212 		JBrowse link
G Ehf ets homologous factor increases expression ISO Asbestos, Serpentine results in increased expression of EHF mRNA CTD PMID:24160326 NCBI chr 3:89,639,845...89,680,061
Ensembl chr 3:89,641,833...89,679,997 		JBrowse link
G Eif3g eukaryotic translation initiation factor 3, subunit G decreases methylation ISO Asbestos, Serpentine results in decreased methylation of EIF3G promoter CTD PMID:29626692 NCBI chr 8:19,429,728...19,433,760
Ensembl chr 8:19,429,643...19,433,808 		JBrowse link
G Eif3h eukaryotic translation initiation factor 3, subunit H increases expression ISO Asbestos, Serpentine results in increased expression of EIF3H mRNA CTD PMID:21148743 NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451 		JBrowse link
G Eif4g3 eukaryotic translation initiation factor 4 gamma, 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of EIF4G3 mRNA CTD PMID:21148743 NCBI chr 5:150,197,410...150,418,862
Ensembl chr 5:150,195,226...150,418,363 		JBrowse link
G Elk1 ETS transcription factor ELK1 increases phosphorylation EXP [Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of ELK1 protein; [Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of ELK1 protein CTD PMID:12495932 NCBI chr  X:1,138,826...1,155,713
Ensembl chr  X:1,139,756...1,155,713 		JBrowse link
G Eln elastin increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of ELN mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of ELN mRNA]		 CTD PMID:21514415 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 increases expression ISO Asbestos, Serpentine results in increased expression of EMILIN1 mRNA CTD PMID:21514415 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Eng endoglin decreases expression ISO Asbestos, Serpentine results in decreased expression of ENG mRNA CTD PMID:16251409 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of ENPP2 gene CTD PMID:29523930 NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827 		JBrowse link
G Epsti1 epithelial stromal interaction 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of EPSTI1 mRNA CTD PMID:29523930 NCBI chr15:53,283,964...53,382,192
Ensembl chr15:53,284,216...53,382,191 		JBrowse link
G Erc2 ELKS/RAB6-interacting/CAST family member 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ERC2 3' UTR CTD PMID:29523930 NCBI chr16:2,812,712...3,673,624
Ensembl chr16:2,848,620...3,670,776 		JBrowse link
G Ereg epiregulin increases expression ISO Asbestos, Serpentine results in increased expression of EREG mRNA CTD PMID:23917077 PMID:24160326 NCBI chr14:17,027,287...17,041,062
Ensembl chr14:17,027,287...17,041,062 		JBrowse link
G Ern2 endoplasmic reticulum to nucleus signaling 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ERN2 promoter CTD PMID:29626692 NCBI chr 1:176,726,454...176,743,289
Ensembl chr 1:176,726,454...176,743,289 		JBrowse link
G Ero1a endoplasmic reticulum oxidoreductase 1 alpha increases expression ISO Asbestos, Serpentine results in increased expression of ERO1A mRNA CTD PMID:29523930 NCBI chr15:18,495,037...18,530,440
Ensembl chr15:18,492,945...18,530,478 		JBrowse link
G Esr2 estrogen receptor 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ESR2 5' UTR CTD PMID:29523930 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Esrrg estrogen-related receptor gamma decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ESRRG 5' UTR CTD PMID:29523930 NCBI chr13:99,167,656...99,788,016
Ensembl chr13:99,564,669...99,783,397 		JBrowse link
G F3 coagulation factor III, tissue factor increases activity
increases expression		 ISO Asbestos, Serpentine results in increased activity of F3 protein
Asbestos, Serpentine results in increased expression of F3 mRNA		 CTD PMID:15636197 PMID:29523930 NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668 		JBrowse link
G Fam124b family with sequence similarity 124 member B increases expression ISO Asbestos, Serpentine results in increased expression of FAM124B mRNA CTD PMID:21148743 NCBI chr 9:81,513,018...81,533,621
Ensembl chr 9:81,515,399...81,533,341 		JBrowse link
G Fam193b family with sequence similarity 193, member B increases expression ISO Asbestos, Serpentine results in increased expression of FAM193B mRNA CTD PMID:21148743 NCBI chr17:9,066,818...9,099,511
Ensembl chr17:9,066,707...9,099,508 		JBrowse link
G Fam20c FAM20C, golgi associated secretory pathway kinase increases expression ISO Asbestos, Serpentine results in increased expression of FAM20C mRNA CTD PMID:29523930 NCBI chr12:15,826,864...15,885,423
Ensembl chr12:15,826,871...15,884,543 		JBrowse link
G Fam3b FAM3 metabolism regulating signaling molecule B increases expression ISO Asbestos, Serpentine results in increased expression of FAM3B mRNA CTD PMID:33581214 NCBI chr11:36,831,532...36,863,902
Ensembl chr11:36,831,532...36,869,713 		JBrowse link
G Farp1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 increases methylation
decreases methylation		 ISO Asbestos, Serpentine results in increased methylation of FARP1 3' UTR
Asbestos, Serpentine results in decreased methylation of FARP1 promoter		 CTD PMID:29523930 PMID:29626692 NCBI chr15:98,124,304...98,363,299
Ensembl chr15:98,182,329...98,363,299 		JBrowse link
G Fbll1 fibrillarin-like 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of FBLL1 mRNA CTD PMID:21148743 NCBI chr10:20,258,656...20,260,299
Ensembl chr10:20,258,656...20,260,299 		JBrowse link
G Fbxo2 F-box protein 2 increases expression ISO Asbestos, Serpentine results in increased expression of FBXO2 mRNA CTD PMID:21148743 NCBI chr 5:158,592,926...158,598,355
Ensembl chr 5:158,592,925...158,598,355 		JBrowse link
G Fcer1g Fc epsilon receptor Ig decreases expression ISO Asbestos, Serpentine results in decreased expression of FCER1G mRNA CTD PMID:24160326 NCBI chr13:83,649,447...83,654,248
Ensembl chr13:83,649,449...83,671,443 		JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of FCHO1 5' UTR CTD PMID:29523930 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases secretion
increases expression		 ISO
EXP		 [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of FGF2 protein
Asbestos, Serpentine results in increased expression of FGF2 mRNA		 CTD PMID:9400719 PMID:23017228 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgl1 fibrinogen-like 1 increases expression ISO Asbestos, Serpentine results in increased expression of FGL1 mRNA CTD PMID:23917077 NCBI chr16:51,120,652...51,150,907
Ensembl chr16:51,120,694...51,151,093 		JBrowse link
G Filip1l filamin A interacting protein 1-like affects methylation ISO Asbestos, Serpentine affects the methylation of FILIP1L 5' UTR CTD PMID:29523930 NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of FLT1 mRNA CTD PMID:16251409 NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fmo3 flavin containing dimethylaniline monoxygenase 3 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of FMO3 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of FMO3 mRNA]		 CTD PMID:16251409 PMID:21514415 NCBI chr13:75,309,367...75,334,915
Ensembl chr13:75,309,374...75,328,028 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
increases metabolic processing		 ISO
EXP		 Asbestos, Serpentine results in increased expression of FN1 mRNA; Asbestos, Serpentine results in increased expression of FN1 protein
TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of FN1 protein]
Asbestos, Serpentine results in increased metabolism of FN1 protein		 CTD PMID:18569384 PMID:21514415 PMID:26685284 PMID:30609805 PMID:33581214 NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fndc9 fibronectin type III domain containing 9 decreases expression ISO Asbestos, Serpentine results in decreased expression of FNDC9 mRNA CTD PMID:21148743 NCBI chr10:30,664,435...30,668,213
Ensembl chr10:30,667,091...30,667,771 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression EXP Asbestos, Serpentine results in increased expression of FOS mRNA; Asbestos, Serpentine results in increased expression of FOS protein CTD PMID:8386370 PMID:32755622 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO Asbestos, Serpentine results in increased expression of FOSL1 mRNA CTD PMID:23917077 PMID:29523930 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930 		JBrowse link
G Foxd2 forkhead box D2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of FOXD2 promoter CTD PMID:29626692 NCBI chr 5:128,427,986...128,430,709
Ensembl chr 5:128,429,020...128,430,504 		JBrowse link
G Foxf2 forkhead box F2 increases expression ISO Asbestos, Serpentine results in increased expression of FOXF2 mRNA CTD PMID:21148743 NCBI chr17:32,835,730...32,842,547
Ensembl chr17:32,836,777...32,842,176 		JBrowse link
G Foxi2 forkhead box I2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of FOXI2 promoter CTD PMID:29626692 NCBI chr 1:190,222,857...190,226,657
Ensembl chr 1:190,222,703...190,226,433 		JBrowse link
G Foxo1 forkhead box O1 decreases expression ISO Asbestos, Serpentine results in decreased expression of FOXO1 mRNA CTD PMID:21148743 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Fst follistatin decreases expression ISO Asbestos, Serpentine results in decreased expression of FST mRNA CTD PMID:24160326 NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571 		JBrowse link
G G0s2 G0/G1switch 2 affects expression ISO Asbestos, Serpentine affects the expression of G0S2 mRNA CTD PMID:24160326 NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase decreases activity
multiple interactions		 ISO
EXP		 Asbestos, Serpentine results in decreased activity of G6PD protein
[Kerosene co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein; [Soot co-treated with Asbestos, Serpentine] results in increased activity of G6PD protein		 CTD PMID:9177657 PMID:16039947 PMID:18370412 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gab2 GRB2-associated binding protein 2 increases expression ISO Asbestos, Serpentine results in increased expression of GAB2 mRNA CTD PMID:21148743 NCBI chr 1:151,429,844...151,625,708
Ensembl chr 1:151,429,695...151,625,031 		JBrowse link
G Gabre gamma-aminobutyric acid type A receptor subunit epsilon decreases expression ISO Asbestos, Serpentine results in decreased expression of GABRE mRNA CTD PMID:29523930 NCBI chr  X:150,060,035...150,078,773
Ensembl chr  X:150,060,040...150,078,693 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression ISO Asbestos, Serpentine results in increased expression of GADD45A mRNA CTD PMID:16251409 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Gak cyclin G associated kinase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of GAK promoter CTD PMID:29626692 NCBI chr14:1,089,853...1,164,098
Ensembl chr14:1,089,866...1,216,398 		JBrowse link
G Galnt18 polypeptide N-acetylgalactosaminyltransferase 18 increases methylation ISO Asbestos, Serpentine results in increased methylation of GALNT18 gene CTD PMID:29523930 NCBI chr 1:165,593,180...165,904,268
Ensembl chr 1:165,593,187...165,904,268 		JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression EXP Asbestos, Serpentine results in increased expression of GAPDH mRNA CTD PMID:7677184 NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235 		JBrowse link
G Gas5 growth arrest specific 5 affects methylation ISO Asbestos, Serpentine affects the methylation of GAS5 gene CTD PMID:29523930 NCBI chr13:73,303,611...73,306,932 JBrowse link
G Gcc2 GRIP and coiled-coil domain containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of GCC2 mRNA CTD PMID:21148743 NCBI chr20:26,247,394...26,293,613
Ensembl chr20:26,247,404...26,293,613 		JBrowse link
G Gdf15 growth differentiation factor 15 increases expression ISO Asbestos, Serpentine results in increased expression of GDF15 mRNA CTD PMID:24160326 NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055 		JBrowse link
G Gfpt2 glutamine-fructose-6-phosphate transaminase 2 increases expression ISO Asbestos, Serpentine results in increased expression of GFPT2 mRNA CTD PMID:24160326 NCBI chr10:34,115,005...34,161,329
Ensembl chr10:34,115,052...34,161,329 		JBrowse link
G Ghr growth hormone receptor increases expression ISO Asbestos, Serpentine results in increased expression of GHR mRNA CTD PMID:33581214 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Gpam glycerol-3-phosphate acyltransferase, mitochondrial decreases expression ISO Asbestos, Serpentine results in decreased expression of GPAM mRNA CTD PMID:24160326 NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639 		JBrowse link
G Gpc5 glypican 5 increases methylation ISO Asbestos, Serpentine results in increased methylation of GPC5 3' UTR CTD PMID:29523930 NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282 		JBrowse link
G Gpr85 G protein-coupled receptor 85 increases methylation ISO Asbestos, Serpentine results in increased methylation of GPR85 5' UTR CTD PMID:29523930 NCBI chr 4:42,100,138...42,109,584
Ensembl chr 4:42,102,941...42,109,566 		JBrowse link
G Gramd1c GRAM domain containing 1C increases expression ISO Asbestos, Serpentine results in increased expression of GRAMD1C mRNA CTD PMID:21148743 NCBI chr11:56,633,229...56,718,570
Ensembl chr11:56,633,227...56,718,570 		JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist increases expression ISO Asbestos, Serpentine results in increased expression of GREM1 mRNA CTD PMID:29523930 NCBI chr 3:100,512,317...100,524,001
Ensembl chr 3:100,512,313...100,524,082 		JBrowse link
G Grin2d glutamate ionotropic receptor NMDA type subunit 2D decreases methylation ISO Asbestos, Serpentine results in decreased methylation of GRIN2D gene CTD PMID:29523930 NCBI chr 1:96,306,871...96,346,994
Ensembl chr 1:96,308,365...96,344,793 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta increases phosphorylation
multiple interactions		 ISO Asbestos, Serpentine results in increased phosphorylation of GSK3B protein
1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one analog inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of GSK3B protein]		 CTD PMID:26685284 PMID:30609805 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of GTF2IRD1 promoter CTD PMID:29626692 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040 		JBrowse link
G Gzma granzyme A decreases expression ISO Asbestos, Serpentine results in decreased expression of GZMA protein CTD PMID:19822075 NCBI chr 2:44,740,569...44,752,502
Ensembl chr 2:44,740,569...44,752,493 		JBrowse link
G H19 H19 imprinted maternally expressed transcript decreases expression ISO Asbestos, Serpentine results in decreased expression of H19 mRNA CTD PMID:29523930 NCBI chr 1:197,730,698...197,733,374
Ensembl chr 1:197,730,698...197,733,134 		JBrowse link
G H6pd hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) multiple interactions ISO Asbestos, Serpentine results in increased metabolism of and results in decreased activity of H6PD protein CTD PMID:20211231 NCBI chr 5:160,434,499...160,470,203
Ensembl chr 5:160,438,697...160,470,171 		JBrowse link
G Hamp hepcidin antimicrobial peptide decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of HAMP mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of HAMP mRNA]		 CTD PMID:21514415 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Has2 hyaluronan synthase 2 increases expression ISO Asbestos, Serpentine results in increased expression of HAS2 mRNA CTD PMID:24160326 NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933 		JBrowse link
G Hdgfl3 HDGF like 3 increases expression ISO Asbestos, Serpentine results in increased expression of HDGFL3 mRNA CTD PMID:21148743 PMID:33581214 NCBI chr 1:135,822,600...135,876,719
Ensembl chr 1:135,827,549...135,876,719 		JBrowse link
G Herc4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 increases expression ISO Asbestos, Serpentine results in increased expression of HERC4 mRNA CTD PMID:29523930 NCBI chr20:25,329,972...25,404,657
Ensembl chr20:25,330,280...25,404,657 		JBrowse link
G Herc6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 decreases expression ISO Asbestos, Serpentine results in decreased expression of HERC6 mRNA CTD PMID:29523930 NCBI chr 4:87,524,470...87,566,895
Ensembl chr 4:87,524,493...87,581,744 		JBrowse link
G Hint3 histidine triad nucleotide binding protein 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of HINT3 mRNA CTD PMID:29523930 NCBI chr 1:27,035,936...27,045,799
Ensembl chr 1:27,035,905...27,047,721 		JBrowse link
G Hipk2 homeodomain interacting protein kinase 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HIPK2 3' UTR CTD PMID:29523930 NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223 		JBrowse link
G Hivep2 HIVEP zinc finger 2 affects expression ISO Asbestos, Serpentine affects the expression of HIVEP2 mRNA CTD PMID:24160326 NCBI chr 1:8,358,205...8,555,993
Ensembl chr 1:8,359,289...8,555,993 		JBrowse link
G Hk2 hexokinase 2 increases expression ISO Asbestos, Serpentine results in increased expression of HK2 mRNA CTD PMID:29523930 NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530 		JBrowse link
G Hlf HLF transcription factor, PAR bZIP family member decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of HLF mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of HLF mRNA]		 CTD PMID:21514415 NCBI chr10:75,154,244...75,211,884
Ensembl chr10:75,154,507...75,211,935 		JBrowse link
G Hmga2 high mobility group AT-hook 2 increases expression ISO Asbestos, Serpentine results in increased expression of HMGA2 mRNA CTD PMID:23917077 NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784 		JBrowse link
G Hmgb1 high mobility group box 1 increases secretion ISO Asbestos, Serpentine results in increased secretion of HMGB1 protein CTD PMID:24160326 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression ISO Asbestos, Serpentine results in increased expression of HMOX1 mRNA CTD PMID:8118652 PMID:16251409 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HNRNPH1 5' UTR CTD PMID:29523930 NCBI chr10:34,692,868...34,702,849
Ensembl chr10:34,693,555...34,702,846 		JBrowse link
G Hnrnpu heterogeneous nuclear ribonucleoprotein U decreases expression ISO Asbestos, Serpentine results in decreased expression of HNRNPU mRNA CTD PMID:29523930 NCBI chr13:90,069,058...90,086,905
Ensembl chr13:90,074,181...90,086,588 		JBrowse link
G Hoxa3 homeobox A3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXA3 promoter CTD PMID:29626692 NCBI chr 4:81,269,243...81,313,218
Ensembl chr 4:81,269,243...81,313,218 		JBrowse link
G Hoxb3 homeo box B3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXB3 promoter CTD PMID:29626692 NCBI chr10:81,258,739...81,314,134
Ensembl chr10:81,299,357...81,313,107 		JBrowse link
G Hoxb7 homeo box B7 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXB7 promoter CTD PMID:29626692 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034 		JBrowse link
G Hoxc11 homeobox C11 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXC11 promoter CTD PMID:29626692 NCBI chr 7:134,091,224...134,094,738
Ensembl chr 7:134,091,552...134,094,738 		JBrowse link
G Hoxd11 homeobox D11 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXD11 promoter CTD PMID:29626692 NCBI chr 3:59,584,840...59,587,257
Ensembl chr 3:59,585,039...59,586,783 		JBrowse link
G Hoxd12 homeo box D12 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HOXD12 promoter CTD PMID:29626692 NCBI chr 3:59,577,677...59,578,798
Ensembl chr 3:59,577,677...59,578,798 		JBrowse link
G Hp haptoglobin decreases expression ISO Asbestos, Serpentine results in decreased expression of HP mRNA CTD PMID:24160326 NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Hras HRas proto-oncogene, GTPase increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of HRAS protein
tobacco tar promotes the reaction [Asbestos, Serpentine results in increased expression of HRAS protein]		 CTD PMID:10905503 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Hs3st1 heparan sulfate-glucosamine 3-sulfotransferase 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of HS3ST1 5' UTR CTD PMID:29523930 NCBI chr14:71,185,826...71,223,263
Ensembl chr14:71,185,682...71,223,248 		JBrowse link
G Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 increases expression
decreases expression		 ISO Asbestos, Serpentine results in increased expression of HSD11B1 mRNA
Asbestos, Serpentine results in decreased expression of HSD11B1 mRNA		 CTD PMID:16251409 PMID:24160326 NCBI chr13:104,728,539...104,798,884
Ensembl chr13:104,728,539...104,788,687 		JBrowse link
G Hsf4 heat shock transcription factor 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HSF4 promoter CTD PMID:29626692 NCBI chr19:33,147,755...33,153,479
Ensembl chr19:33,147,755...33,153,479 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 increases expression ISO Asbestos, Serpentine results in increased expression of HSP90B1 mRNA CTD PMID:25324550 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa2 heat shock protein family A (Hsp70) member 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of HSPA2 mRNA CTD PMID:29523930 NCBI chr 6:95,128,504...95,131,281
Ensembl chr 6:95,128,350...95,131,287 		JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 increases methylation ISO Asbestos, Serpentine results in increased methylation of HSPA4 5' UTR CTD PMID:29523930 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression ISO Asbestos, Serpentine results in increased expression of HSPA5 mRNA; Asbestos, Serpentine results in increased expression of HSPA5 protein CTD PMID:25324550 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Htra1 HtrA serine peptidase 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of HTRA1 gene CTD PMID:29523930 NCBI chr 1:185,497,815...185,547,380
Ensembl chr 1:185,497,735...185,547,379 		JBrowse link
G Icam5 intercellular adhesion molecule 5 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ICAM5 5' UTR CTD PMID:29523930 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588 		JBrowse link
G Ifi44 interferon-induced protein 44 decreases expression ISO Asbestos, Serpentine results in decreased expression of IFI44 mRNA CTD PMID:29523930 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844 		JBrowse link
G Ifit2 interferon-induced protein with tetratricopeptide repeats 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of IFIT2 mRNA CTD PMID:21148743 PMID:29523930 NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635 		JBrowse link
G Ifit3 interferon-induced protein with tetratricopeptide repeats 3 increases expression
decreases expression		 ISO Asbestos, Serpentine results in increased expression of IFIT3 mRNA
Asbestos, Serpentine results in decreased expression of IFIT3 mRNA		 CTD PMID:24160326 PMID:29523930 NCBI chr 1:232,114,166...232,119,311
Ensembl chr 1:232,114,166...232,119,307 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of IFITM1 mRNA CTD PMID:24160326 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifng interferon gamma decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of IFNG protein
[Asbestos, Serpentine results in decreased susceptibility to Asbestos, Serpentine] which results in decreased expression of IFNG protein		 CTD PMID:21148743 PMID:22608188 PMID:23449737 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Ifngr2 interferon gamma receptor 2 affects expression ISO Asbestos, Serpentine affects the expression of IFNGR2 mRNA CTD PMID:24160326 NCBI chr11:30,779,733...30,798,005
Ensembl chr11:30,779,733...30,798,005 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Asbestos, Serpentine results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Igf2 insulin-like growth factor 2 increases expression ISO Asbestos, Serpentine results in increased expression of IGF2 mRNA CTD PMID:24160326 NCBI chr 1:197,814,409...197,831,802
Ensembl chr 1:197,814,410...197,823,018 		JBrowse link
G Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 increases expression ISO Asbestos, Serpentine results in increased expression of IGF2BP2 mRNA CTD PMID:21148743 NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377 		JBrowse link
G Igfbp3 insulin-like growth factor binding protein 3 increases expression ISO Asbestos, Serpentine results in increased expression of IGFBP3 mRNA CTD PMID:21148743 NCBI chr14:82,056,347...82,064,083
Ensembl chr14:82,056,347...82,064,083 		JBrowse link
G Igfbp6 insulin-like growth factor binding protein 6 decreases expression ISO Asbestos, Serpentine results in decreased expression of IGFBP6 mRNA CTD PMID:16251409 PMID:29523930 NCBI chr 7:133,276,309...133,280,944
Ensembl chr 7:133,276,234...133,280,966 		JBrowse link
G Il10 interleukin 10 decreases expression
multiple interactions
increases expression		 ISO Asbestos, Serpentine results in decreased expression of IL10 protein
[Asbestos, Serpentine results in decreased susceptibility to Asbestos, Serpentine] which results in increased expression of IL10 protein
Asbestos, Serpentine results in increased expression of IL10 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL10 protein]		 CTD PMID:17200189 PMID:22608188 PMID:23449737 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il12b interleukin 12B increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of IL12B protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]		 CTD PMID:17200189 PMID:18403674 PMID:21514415 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il13 interleukin 13 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of IL13 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL13 protein]		 CTD PMID:17200189 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il18 interleukin 18 decreases expression ISO Asbestos, Serpentine results in decreased expression of IL18 mRNA CTD PMID:24160326 NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887 		JBrowse link
G Il19 interleukin 19 increases expression ISO Asbestos, Serpentine results in increased expression of IL19 mRNA CTD PMID:24160326 NCBI chr13:42,397,715...42,411,637
Ensembl chr13:42,399,138...42,405,473 		JBrowse link
G Il1a interleukin 1 alpha increases expression
multiple interactions		 ISO
EXP		 Asbestos, Serpentine results in increased expression of IL1A protein
Asbestos, Serpentine results in increased expression of IL1A mRNA
[Asbestos, Serpentine co-treated with Lipopolysaccharides] results in increased expression of IL1A mRNA		 CTD PMID:9400719 PMID:17200189 PMID:24160326 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta increases expression
multiple interactions
increases secretion		 ISO
EXP		 Asbestos, Serpentine results in increased expression of IL1B mRNA
[Asbestos, Serpentine co-treated with IL1B protein] results in increased abundance of 3-nitrotyrosine; [Asbestos, Serpentine co-treated with IL1B protein] results in increased abundance of Nitrates; [Asbestos, Serpentine co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [Asbestos, Serpentine co-treated with IL1B protein] results in increased expression of NOS2 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAP3K8 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAPK1 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAPK3 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of RELA protein; Asbestos, Serpentine promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]; Cytochalasin B inhibits the reaction [Asbestos, Serpentine promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; IL1RN protein inhibits the reaction [[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of IL6 protein]; pimagedine inhibits the reaction [Asbestos, Serpentine promotes the reaction [IL1B protein results in increased abundance of Nitric Oxide]]; tyrosyl-valyl-alanyl-aspartic acid fluoromethyl ketone analog inhibits the reaction [Asbestos, Serpentine results in increased secretion of IL1B protein]
[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of CSF2 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of FGF2 protein; [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of IL6 protein; Asbestos, Serpentine results in increased secretion of IL1B protein
Asbestos, Serpentine results in increased expression of IL1B mRNA; Asbestos, Serpentine results in increased expression of IL1B protein
Asbestos, Serpentine promotes the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Asbestos, Serpentine promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]; IL1B protein promotes the reaction [Asbestos, Serpentine results in increased expression of CCL2 mRNA]; IL1B protein promotes the reaction [Asbestos, Serpentine results in increased secretion of CCL2 protein]
NLRP3 protein affects the reaction [Asbestos, Serpentine results in increased expression of IL1B protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL1B protein]		 CTD PMID:8473757 PMID:9698594 PMID:10444523 PMID:10923243 PMID:16251409 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Asbestos, Serpentine results in increased expression of IL1RL1 mRNA CTD PMID:23917077 PMID:24160326 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il1rn interleukin 1 receptor antagonist increases secretion
multiple interactions
increases expression		 ISO Asbestos, Serpentine results in increased secretion of IL1RN protein
IL1RN protein inhibits the reaction [[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of IL6 protein]
Asbestos, Serpentine results in increased expression of IL1RN mRNA		 CTD PMID:23017228 PMID:24160326 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il2 interleukin 2 increases secretion ISO Asbestos, Serpentine results in increased secretion of IL2 protein CTD PMID:23017228 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il24 interleukin 24 increases expression ISO Asbestos, Serpentine results in increased expression of IL24 mRNA CTD PMID:24160326 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487 		JBrowse link
G Il4 interleukin 4 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of IL4 mRNA; Asbestos, Serpentine results in increased expression of IL4 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL4 protein]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of IL4 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL4 protein]		 CTD PMID:16251409 PMID:17200189 PMID:21514415 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il5 interleukin 5 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of IL5 protein
PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL5 protein]		 CTD PMID:16251409 PMID:17200189 PMID:21514415 NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213 		JBrowse link
G Il6 interleukin 6 increases secretion
multiple interactions
increases expression		 ISO
EXP		 [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of IL6 protein; Asbestos, Serpentine results in increased secretion of IL6 protein
IL1RN protein inhibits the reaction [[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased secretion of IL6 protein]
Asbestos, Serpentine results in increased expression of IL6 mRNA; Asbestos, Serpentine results in increased expression of IL6 protein
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL6 protein]
[Asbestos, Serpentine co-treated with Lipopolysaccharides] results in increased expression of IL6 mRNA		 CTD PMID:9400719 PMID:15790520 PMID:16251409 PMID:17200189 PMID:21514415 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il6st interleukin 6 cytokine family signal transducer increases expression ISO Asbestos, Serpentine results in increased expression of IL6ST mRNA CTD PMID:16251409 NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936 		JBrowse link
G Il7r interleukin 7 receptor increases expression ISO Asbestos, Serpentine results in increased expression of IL7R mRNA CTD PMID:16251409 PMID:24160326 NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757 		JBrowse link
G Inhba inhibin subunit beta A decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of INHBA mRNA
Asbestos, Serpentine results in increased expression of INHBA mRNA		 CTD PMID:24160326 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Iqce IQ motif containing E decreases methylation ISO Asbestos, Serpentine results in decreased methylation of IQCE gene CTD PMID:29523930 NCBI chr12:13,943,290...13,982,708
Ensembl chr12:13,943,487...13,982,693 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of IQGAP1 mRNA CTD PMID:16251409 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Irak2 interleukin-1 receptor-associated kinase 2 affects expression ISO Asbestos, Serpentine affects the expression of IRAK2 mRNA CTD PMID:24160326 NCBI chr 4:146,786,004...146,842,615
Ensembl chr 4:146,786,100...146,842,602 		JBrowse link
G Irf8 interferon regulatory factor 8 decreases expression ISO Asbestos, Serpentine results in decreased expression of IRF8 mRNA CTD PMID:24160326 NCBI chr19:48,790,581...48,812,363
Ensembl chr19:48,790,588...48,811,829 		JBrowse link
G Irf9 interferon regulatory factor 9 decreases expression ISO Asbestos, Serpentine results in decreased expression of IRF9 mRNA CTD PMID:21148743 NCBI chr15:29,095,474...29,101,924
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Irs2 insulin receptor substrate 2 increases expression ISO Asbestos, Serpentine results in increased expression of IRS2 mRNA CTD PMID:29523930 NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482 		JBrowse link
G Irx4 iroquois homeobox 4 increases expression ISO Asbestos, Serpentine results in increased expression of IRX4 mRNA CTD PMID:33581214 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549 		JBrowse link
G Irx5 iroquois homeobox 5 increases expression ISO Asbestos, Serpentine results in increased expression of IRX5 mRNA CTD PMID:21148743 NCBI chr19:14,639,052...14,643,911
Ensembl chr19:14,624,225...14,642,318 		JBrowse link
G Isg15 ISG15 ubiquitin-like modifier decreases expression ISO Asbestos, Serpentine results in decreased expression of ISG15 mRNA CTD PMID:29523930 NCBI chr 5:166,784,148...166,785,435
Ensembl chr 5:166,784,148...166,785,435 		JBrowse link
G Itgax integrin subunit alpha X increases expression ISO Asbestos, Serpentine results in increased expression of ITGAX mRNA CTD PMID:16251409 NCBI chr 1:182,709,653...182,740,709
Ensembl chr 1:182,719,609...182,740,698 		JBrowse link
G Itgb7 integrin subunit beta 7 decreases expression ISO Asbestos, Serpentine results in decreased expression of ITGB7 mRNA CTD PMID:21148743 NCBI chr 7:133,347,927...133,364,955
Ensembl chr 7:133,347,960...133,364,876 		JBrowse link
G Itgb8 integrin subunit beta 8 increases expression
decreases methylation		 ISO Asbestos, Serpentine results in increased expression of ITGB8 mRNA
Asbestos, Serpentine results in decreased methylation of ITGB8 gene		 CTD PMID:24160326 PMID:29523930 PMID:33581214 NCBI chr 6:140,125,002...140,208,261
Ensembl chr 6:140,127,203...140,208,476 		JBrowse link
G Itprip inositol 1,4,5-trisphosphate receptor interacting protein affects expression ISO Asbestos, Serpentine affects the expression of ITPRIP mRNA CTD PMID:24160326 NCBI chr 1:246,762,804...246,786,379
Ensembl chr 1:246,762,472...246,786,408 		JBrowse link
G Itpripl2 ITPRIP like 2 increases expression ISO Asbestos, Serpentine results in increased expression of ITPRIPL2 mRNA CTD PMID:33581214 NCBI chr 1:172,801,152...172,803,047
Ensembl chr 1:172,796,849...172,802,950 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of JARID2 mRNA CTD PMID:24160326 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Jchain joining chain of multimeric IgA and IgM increases expression ISO Asbestos, Serpentine results in increased expression of JCHAIN mRNA CTD PMID:16251409 NCBI chr14:19,538,927...19,547,023
Ensembl chr14:19,538,952...19,546,298 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
increases expression		 ISO
EXP		 Asbestos, Serpentine results in increased expression of and results in increased phosphorylation of JUN protein; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased expression of and results in increased phosphorylation of JUN protein]
Asbestos, Serpentine results in increased expression of JUN mRNA; Asbestos, Serpentine results in increased expression of JUN protein		 CTD PMID:8386370 PMID:19116364 PMID:32755622 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Kcna4 potassium voltage-gated channel subfamily A member 4 increases methylation ISO Asbestos, Serpentine results in increased methylation of KCNA4 exon CTD PMID:29523930 NCBI chr 3:93,756,399...93,778,004
Ensembl chr 3:93,756,446...93,769,162 		JBrowse link
G Kcnb2 potassium voltage-gated channel subfamily B member 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of KCNB2 gene CTD PMID:29523930 NCBI chr 5:3,567,012...4,028,564
Ensembl chr 5:3,569,685...4,028,599 		JBrowse link
G Kcnd2 potassium voltage-gated channel subfamily D member 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of KCND2 gene CTD PMID:29523930 NCBI chr 4:49,775,812...50,277,746
Ensembl chr 4:49,776,246...50,277,728 		JBrowse link
G Kcnk2 potassium two pore domain channel subfamily K member 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of KCNK2 gene CTD PMID:29523930 NCBI chr13:100,766,101...100,963,435
Ensembl chr13:100,766,113...100,963,435 		JBrowse link
G Kctd12 potassium channel tetramerization domain containing 12 decreases expression ISO Asbestos, Serpentine results in decreased expression of KCTD12 mRNA CTD PMID:29523930 NCBI chr15:79,800,078...79,806,017
Ensembl chr15:79,801,191...79,806,282 		JBrowse link
G Kdm6b lysine demethylase 6B increases expression
multiple interactions
affects expression		 ISO Asbestos, Serpentine results in increased expression of KDM6B mRNA
Asbestos, Serpentine promotes the reaction [KDM6B protein affects the expression of TNF mRNA]; Asbestos, Serpentine promotes the reaction [STAT6 protein binds to KDM6B promoter]; KDM6B protein affects the reaction [Asbestos, Serpentine results in increased expression of RETNLA mRNA]; KDM6B protein affects the reaction [Asbestos, Serpentine results in increased expression of TNF mRNA]; leflunomide inhibits the reaction [Asbestos, Serpentine results in increased expression of KDM6B mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of KDM6B mRNA]		 CTD PMID:26699812 NCBI chr10:54,120,716...54,142,212
Ensembl chr10:54,121,848...54,130,794 		JBrowse link
G Kif20a kinesin family member 20A increases expression ISO Asbestos, Serpentine results in increased expression of KIF20A mRNA CTD PMID:24160326 NCBI chr18:26,230,294...26,238,780
Ensembl chr18:26,230,230...26,238,780 		JBrowse link
G Klf12 KLF transcription factor 12 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of KLF12 5' UTR CTD PMID:29523930 NCBI chr15:76,628,778...77,062,000
Ensembl chr15:76,637,654...77,062,056 		JBrowse link
G Klhl36 kelch-like family member 36 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of KLHL36 gene CTD PMID:29523930 NCBI chr19:47,921,590...47,942,627
Ensembl chr19:47,921,590...47,942,620 		JBrowse link
G Klk1 kallikrein 1 increases activity ISO Asbestos, Serpentine results in increased activity of KLK1 protein CTD PMID:10777245 NCBI chr 1:94,642,644...94,646,760
Ensembl chr 1:94,642,687...94,646,754 		JBrowse link
G Klrk1 killer cell lectin like receptor K1 decreases expression ISO Asbestos, Serpentine results in decreased expression of KLRK1 protein CTD PMID:19822075 NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459 		JBrowse link
G Krt17 keratin 17 decreases expression ISO Asbestos, Serpentine results in decreased expression of KRT17 mRNA CTD PMID:29523930 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392 		JBrowse link
G Krt18 keratin 18 decreases expression ISO Asbestos, Serpentine results in decreased expression of KRT18 mRNA CTD PMID:29523930 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166 		JBrowse link
G Krt19 keratin 19 decreases expression ISO Asbestos, Serpentine results in decreased expression of KRT19 mRNA CTD PMID:24160326 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt81 keratin 81 increases expression ISO Asbestos, Serpentine results in increased expression of KRT81 mRNA CTD PMID:29523930 NCBI chr 7:132,577,112...132,582,238
Ensembl chr 7:132,576,492...132,582,170 		JBrowse link
G Kynu kynureninase increases expression ISO Asbestos, Serpentine results in increased expression of KYNU mRNA CTD PMID:24160326 NCBI chr 3:27,778,646...27,929,470
Ensembl chr 3:27,778,772...27,929,488 		JBrowse link
G L3mbtl1 L3MBTL histone methyl-lysine binding protein 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of L3MBTL1 5' UTR CTD PMID:29523930 NCBI chr 3:151,597,903...151,633,657
Ensembl chr 3:151,602,980...151,631,233 		JBrowse link
G Lamc1 laminin subunit gamma 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of LAMC1 gene CTD PMID:29523930 NCBI chr13:65,374,372...65,501,492
Ensembl chr13:65,374,372...65,501,492 		JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Asbestos, Serpentine results in increased expression of LAMC2 mRNA CTD PMID:23917077 NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Asbestos, Serpentine results in increased expression of LCN2 mRNA CTD PMID:16251409 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Ldhb lactate dehydrogenase B increases methylation ISO Asbestos, Serpentine results in increased methylation of LDHB gene CTD PMID:29523930 NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403 		JBrowse link
G Ldlrad4 low density lipoprotein receptor class A domain containing 4 increases methylation ISO Asbestos, Serpentine results in increased methylation of LDLRAD4 5' UTR CTD PMID:29523930 NCBI chr18:61,519,253...61,848,403
Ensembl chr18:61,521,428...61,843,238 		JBrowse link
G Lep leptin decreases expression ISO Asbestos, Serpentine results in decreased expression of LEP mRNA CTD PMID:23917077 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lhx2 LIM homeobox 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LHX2 promoter CTD PMID:29626692 NCBI chr 3:22,113,619...22,143,909
Ensembl chr 3:22,126,007...22,143,908 		JBrowse link
G Lhx8 LIM homeobox 8 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LHX8 gene CTD PMID:29523930 NCBI chr 2:243,244,958...243,269,624
Ensembl chr 2:243,244,961...243,269,416 		JBrowse link
G Lif LIF, interleukin 6 family cytokine decreases expression ISO Asbestos, Serpentine results in decreased expression of LIF mRNA CTD PMID:21148743 NCBI chr14:79,131,049...79,140,486
Ensembl chr14:79,134,574...79,140,482 		JBrowse link
G Lmo3 LIM domain only 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LMO3 5' UTR CTD PMID:29523930 NCBI chr 4:171,234,686...171,297,677
Ensembl chr 4:171,234,696...171,292,222 		JBrowse link
G Lmo7 LIM domain 7 increases methylation ISO Asbestos, Serpentine results in increased methylation of LMO7 exon CTD PMID:29523930 NCBI chr15:78,566,999...78,769,833
Ensembl chr15:78,567,023...78,769,783 		JBrowse link
G Lmod2 leiomodin 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LMOD2 3' UTR CTD PMID:29523930 NCBI chr 4:53,067,428...53,075,124
Ensembl chr 4:53,067,428...53,075,120 		JBrowse link
G Lmx1a LIM homeobox transcription factor 1 alpha decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LMX1A gene CTD PMID:29523930 NCBI chr13:79,834,614...79,978,253
Ensembl chr13:79,835,019...79,978,253 		JBrowse link
G LOC120094551 U6 spliceosomal RNA increases expression ISO Asbestos, Serpentine results in increased expression of RNU6-1 mRNA CTD PMID:29523930 NCBI chr 8:63,594,040...63,594,146
Ensembl chr 8:63,594,040...63,594,146 		JBrowse link
G LOC120098377 U1 spliceosomal RNA increases expression ISO Asbestos, Serpentine results in increased expression of RNVU1-7 mRNA CTD PMID:29523930 NCBI chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477
Ensembl chr18:79,901,335...79,901,477 		JBrowse link
G LOC120098722 5S ribosomal RNA increases expression ISO Asbestos, Serpentine results in increased expression of RNA5S9 mRNA CTD PMID:29523930 NCBI chr19:51,610,075...51,610,193
Ensembl chr19:51,610,075...51,610,193 		JBrowse link
G Loxl2 lysyl oxidase-like 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LOXL2 5' UTR CTD PMID:29523930 NCBI chr15:44,683,449...44,773,067
Ensembl chr15:44,683,880...44,773,067 		JBrowse link
G Lrrc2 leucine rich repeat containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of LRRC2 mRNA CTD PMID:21148743 NCBI chr 8:110,936,119...110,969,189
Ensembl chr 8:110,938,165...110,969,185 		JBrowse link
G Lrrc66 leucine rich repeat containing 66 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LRRC66 3' UTR CTD PMID:29523930 NCBI chr14:34,578,934...34,604,977
Ensembl chr14:34,581,240...34,604,541 		JBrowse link
G Ltk leukocyte receptor tyrosine kinase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of LTK promoter CTD PMID:29626692 NCBI chr 3:106,734,675...106,741,552
Ensembl chr 3:106,734,676...106,743,369 		JBrowse link
G Luzp1 leucine zipper protein 1 affects expression ISO Asbestos, Serpentine affects the expression of LUZP1 mRNA CTD PMID:24160326 NCBI chr 5:148,706,094...148,781,616
Ensembl chr 5:148,706,138...148,781,609 		JBrowse link
G Macir macrophage immunometabolism regulator decreases expression ISO Asbestos, Serpentine results in decreased expression of MACIR mRNA CTD PMID:21148743 NCBI chr 9:98,420,760...98,440,818
Ensembl chr 9:98,420,376...98,441,733 		JBrowse link
G Mal mal, T-cell differentiation protein increases expression ISO Asbestos, Serpentine results in increased expression of MAL mRNA CTD PMID:33581214 NCBI chr 3:114,864,378...114,888,136
Ensembl chr 3:114,864,378...114,888,136 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression ISO Asbestos, Serpentine results in increased expression of MAP1LC3B mRNA CTD PMID:24735948 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 affects expression ISO Asbestos, Serpentine affects the expression of MAP2K1 mRNA CTD PMID:24160326 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map3k12 mitogen activated protein kinase kinase kinase 12 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MAP3K12 promoter CTD PMID:29626692 NCBI chr 7:133,630,267...133,648,464
Ensembl chr 7:133,630,835...133,640,789 		JBrowse link
G Map3k4 mitogen activated protein kinase kinase kinase 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MAP3K4 promoter CTD PMID:29626692 NCBI chr 1:48,431,801...48,519,358
Ensembl chr 1:48,431,830...48,519,358 		JBrowse link
G Map3k6 mitogen-activated protein kinase kinase kinase 6 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MAP3K6 promoter CTD PMID:29626692 NCBI chr 5:145,440,126...145,452,213
Ensembl chr 5:145,440,346...145,452,212 		JBrowse link
G Map3k8 mitogen-activated protein kinase kinase kinase 8 increases phosphorylation
multiple interactions		 ISO Asbestos, Serpentine results in increased phosphorylation of MAP3K8 protein
[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAP3K8 protein		 CTD PMID:23017228 NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases phosphorylation
decreases phosphorylation		 ISO
EXP		 [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAPK1 protein
Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein
Asbestos, Serpentine results in decreased phosphorylation of MAPK1 protein
Asbestos, Serpentine promotes the reaction [MAPK1 protein binds to PRKD1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein]
[Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein] which results in increased phosphorylation of ELK1 protein; Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein		 CTD PMID:10751356 PMID:12495932 PMID:16571779 PMID:19116364 PMID:23017228 More... NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk14 mitogen activated protein kinase 14 increases phosphorylation ISO Asbestos, Serpentine results in increased phosphorylation of MAPK14 protein CTD PMID:15882436 NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 decreases phosphorylation
multiple interactions
increases phosphorylation		 ISO
EXP		 Asbestos, Serpentine results in decreased phosphorylation of MAPK3 protein
[Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of MAPK3 protein
Asbestos, Serpentine promotes the reaction [MAPK3 protein binds to PRKD1 protein]; N-(2(R)-2-(hydroxamidocarbonylmethyl)-4-methylpentanoyl)-L-tryptophan methylamide inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein]
[Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein] which results in increased phosphorylation of ELK1 protein; Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein		 CTD PMID:10751356 PMID:12495932 PMID:16571779 PMID:19116364 PMID:23017228 More... NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein] CTD PMID:15882436 PMID:24735948 NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Mapk9 mitogen-activated protein kinase 9 multiple interactions
increases phosphorylation		 ISO Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK9 protein] CTD PMID:24735948 NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178 		JBrowse link
G Mapt microtubule-associated protein tau decreases expression ISO Asbestos, Serpentine results in decreased expression of MAPT mRNA CTD PMID:16251409 NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129 		JBrowse link
G Marchf3 membrane associated ring-CH-type finger 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of MARCHF3 mRNA CTD PMID:21148743 NCBI chr18:50,237,218...50,389,343
Ensembl chr18:50,237,230...50,389,150 		JBrowse link
G Mb myoglobin decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of MB mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MB mRNA]		 CTD PMID:21514415 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383 		JBrowse link
G Mbnl1 muscleblind-like splicing regulator 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of MBNL1 exon CTD PMID:29523930 NCBI chr 2:144,639,819...144,814,395
Ensembl chr 2:144,670,285...144,814,368 		JBrowse link
G Mcam melanoma cell adhesion molecule increases expression ISO Asbestos, Serpentine results in increased expression of MCAM mRNA CTD PMID:24160326 NCBI chr 8:44,479,391...44,487,575
Ensembl chr 8:44,479,376...44,487,571 		JBrowse link
G Mcf2l MCF.2 cell line derived transforming sequence-like decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MCF2L promoter CTD PMID:29626692 NCBI chr16:76,507,133...76,652,893
Ensembl chr16:76,507,133...76,652,733 		JBrowse link
G Med19 mediator complex subunit 19 increases expression ISO Asbestos, Serpentine results in increased expression of MED19 mRNA CTD PMID:21148743 NCBI chr 3:69,762,138...69,772,661
Ensembl chr 3:69,762,166...69,772,036 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase decreases expression ISO Asbestos, Serpentine results in decreased expression of MERTK mRNA CTD PMID:21148743 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554 		JBrowse link
G Mfsd4a major facilitator superfamily domain containing 4A decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MFSD4A 5' UTR CTD PMID:29523930 NCBI chr13:43,469,488...43,510,467
Ensembl chr13:43,469,488...43,510,467 		JBrowse link
G Mgat4c MGAT4 family, member C increases methylation ISO Asbestos, Serpentine results in increased methylation of MGAT4C 5' UTR CTD PMID:29523930 NCBI chr 7:36,709,564...37,485,810
Ensembl chr 7:37,260,321...37,474,571 		JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 increases expression ISO Asbestos, Serpentine results in increased expression of MGST1 mRNA CTD PMID:29523930 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892 		JBrowse link
G Mia3 MIA SH3 domain ER export factor 3 increases expression ISO Asbestos, Serpentine results in increased expression of MIA3 mRNA CTD PMID:21148743 NCBI chr13:94,970,421...95,012,071
Ensembl chr13:94,970,424...95,011,972 		JBrowse link
G Miip migration and invasion inhibitory protein increases methylation ISO Asbestos, Serpentine results in increased methylation of MIIP 5' UTR CTD PMID:29523930 NCBI chr 5:158,292,510...158,299,533
Ensembl chr 5:158,292,511...158,299,694 		JBrowse link
G Mir129-2 microRNA 129-2 increases methylation ISO Asbestos, Serpentine results in increased methylation of MIR129-2 5' UTR CTD PMID:29523930 NCBI chr 3:80,202,044...80,202,140
Ensembl chr 3:80,202,044...80,202,140 		JBrowse link
G Mir30d microRNA 30d decreases expression ISO Asbestos, Serpentine results in decreased expression of MIR30D mRNA CTD PMID:28979837 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472 		JBrowse link
G Mki67 marker of proliferation Ki-67 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of MKI67 protein
[MPO protein affects the susceptibility to Asbestos, Serpentine] which affects the expression of MKI67 protein; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MKI67 protein]		 CTD PMID:16266986 PMID:17200189 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762 		JBrowse link
G Mknk2 MAPK interacting serine/threonine kinase 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MKNK2 promoter CTD PMID:29626692 NCBI chr 7:9,039,771...9,050,832
Ensembl chr 7:9,039,728...9,050,827 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Asbestos, Serpentine results in increased expression of MMP1 mRNA CTD PMID:24160326 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp10 matrix metallopeptidase 10 increases expression ISO Asbestos, Serpentine results in increased expression of MMP10 mRNA CTD PMID:23917077 NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748 		JBrowse link
G Mmp12 matrix metallopeptidase 12 multiple interactions
increases activity
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; rottlerin inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]
Asbestos, Serpentine results in increased activity of MMP12 protein		 CTD PMID:16251409 PMID:16571779 NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp13 matrix metallopeptidase 13 multiple interactions
increases expression		 ISO 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; rottlerin inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; RTKI cpd inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA]; U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA] CTD PMID:16571779 PMID:23917077 NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp14 matrix metallopeptidase 14 increases expression ISO Asbestos, Serpentine results in increased expression of MMP14 mRNA CTD PMID:21514415 NCBI chr15:27,887,795...27,897,020
Ensembl chr15:27,887,727...27,899,864 		JBrowse link
G Mmp2 matrix metallopeptidase 2 increases secretion
increases activity		 ISO Asbestos, Serpentine results in increased secretion of MMP2 protein
Asbestos, Serpentine results in increased activity of MMP2 protein		 CTD PMID:16571779 PMID:26685284 PMID:30609805 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp20 matrix metallopeptidase 20 increases expression ISO Asbestos, Serpentine results in increased expression of MMP20 mRNA CTD PMID:21514415 NCBI chr 8:4,789,415...4,830,035
Ensembl chr 8:4,789,415...4,830,035 		JBrowse link
G Mmp3 matrix metallopeptidase 3 increases expression
decreases expression		 ISO Asbestos, Serpentine results in increased expression of MMP3 mRNA
Asbestos, Serpentine results in decreased expression of MMP3 mRNA		 CTD PMID:16251409 PMID:23917077 PMID:24160326 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression
increases secretion		 ISO Asbestos, Serpentine results in increased expression of MMP7
Asbestos, Serpentine results in increased secretion of MMP7 protein
Asbestos, Serpentine results in increased expression of MMP7 mRNA		 CTD PMID:19105532 PMID:33581214 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases secretion
increases activity
increases expression		 ISO Asbestos, Serpentine results in increased secretion of MMP9 protein
Asbestos, Serpentine results in increased activity of MMP9 protein
Asbestos, Serpentine results in increased expression of MMP9; Asbestos, Serpentine results in increased expression of MMP9 mRNA		 CTD PMID:16571779 PMID:18039278 PMID:19105532 PMID:26685284 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mnda myeloid cell nuclear differentiation antigen decreases expression ISO Asbestos, Serpentine results in decreased expression of MNDA mRNA CTD PMID:21148743 NCBI chr13:86,017,888...86,035,556
Ensembl chr13:86,017,892...86,034,201 		JBrowse link
G Mpo myeloperoxidase increases expression
affects response to substance
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of MPO protein
MPO protein affects the susceptibility to Asbestos, Serpentine
[MPO protein affects the susceptibility to Asbestos, Serpentine] which affects the expression of CCND1 protein; [MPO protein affects the susceptibility to Asbestos, Serpentine] which affects the expression of MKI67 protein		 CTD PMID:16266986 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrgprx3 MAS related GPR family member X3 affects expression ISO Asbestos, Serpentine affects the expression of MRGPRX3 mRNA CTD PMID:24160326 NCBI chr 1:97,720,377...97,746,953
Ensembl chr 1:97,721,436...97,746,900 		JBrowse link
G Msln mesothelin increases expression EXP Asbestos, Serpentine results in increased expression of MSLN protein CTD PMID:20933535 NCBI chr10:14,771,946...14,781,382
Ensembl chr10:14,771,961...14,777,643 		JBrowse link
G Msrb1 methionine sulfoxide reductase B1 increases methylation ISO Asbestos, Serpentine results in increased methylation of MSRB1 gene CTD PMID:29523930 NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609 		JBrowse link
G Mt1 metallothionein 1 increases expression ISO Asbestos, Serpentine results in increased expression of MT1 mRNA CTD PMID:16251409 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049 		JBrowse link
G Mtcl2 microtubule crosslinking factor 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of MTCL2 mRNA CTD PMID:29523930 NCBI chr 3:145,669,102...145,741,578
Ensembl chr 3:145,675,443...145,740,871 		JBrowse link
G Mthfsd methenyltetrahydrofolate synthetase domain containing decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MTHFSD promoter CTD PMID:29626692 NCBI chr19:49,164,266...49,178,233
Ensembl chr19:49,167,183...49,178,232 		JBrowse link
G Mtor mechanistic target of rapamycin kinase decreases phosphorylation ISO Asbestos, Serpentine results in decreased phosphorylation of MTOR protein CTD PMID:24735948 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mx1 MX dynamin like GTPase 1 decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of MX1 mRNA
Asbestos, Serpentine results in increased expression of MX1 mRNA		 CTD PMID:24160326 PMID:29523930 NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507 		JBrowse link
G Mxd1 max dimerization protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of MXD1 mRNA CTD PMID:21148743 NCBI chr 4:119,097,353...119,118,080
Ensembl chr 4:119,097,353...119,117,751 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor multiple interactions
increases expression		 ISO aluminum citrate inhibits the reaction [Asbestos, Serpentine results in increased expression of MYC mRNA]; Sodium Selenite inhibits the reaction [Asbestos, Serpentine results in increased expression of MYC mRNA] CTD PMID:11198217 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myl4 myosin, light chain 4 decreases expression ISO Asbestos, Serpentine results in decreased expression of MYL4 mRNA CTD PMID:16251409 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myl7 myosin light chain 7 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of MYL7 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYL7 mRNA]		 CTD PMID:21514415 PMID:29523930 NCBI chr14:80,780,684...80,783,259
Ensembl chr14:80,779,776...80,783,244 		JBrowse link
G Mylk3 myosin light chain kinase 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of MYLK3 promoter CTD PMID:29626692 NCBI chr19:21,685,085...21,743,587
Ensembl chr19:21,691,929...21,742,954 		JBrowse link
G Myoz2 myozenin 2 decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of MYOZ2 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYOZ2 mRNA]		 CTD PMID:21514415 NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221 		JBrowse link
G Myrip myosin VIIA and Rab interacting protein decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of MYRIP mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYRIP mRNA]		 CTD PMID:21514415 NCBI chr 8:120,017,749...120,184,821
Ensembl chr 8:120,017,524...120,183,833 		JBrowse link
G Naa16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit increases methylation ISO Asbestos, Serpentine results in increased methylation of NAA16 3' UTR CTD PMID:29523930 NCBI chr15:54,711,620...54,770,915
Ensembl chr15:54,711,621...54,770,896 		JBrowse link
G Napsa napsin A aspartic peptidase decreases expression ISO Asbestos, Serpentine results in decreased expression of NAPSA mRNA CTD PMID:21148743 NCBI chr 1:95,064,726...95,077,101
Ensembl chr 1:95,064,900...95,077,094 		JBrowse link
G Ncf2 neutrophil cytosolic factor 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of NCF2 mRNA CTD PMID:24160326 NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277 		JBrowse link
G Ncr1 natural cytotoxicity triggering receptor 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of NCR1 protein CTD PMID:19822075 NCBI chr 1:69,614,744...69,622,594
Ensembl chr 1:69,616,601...69,660,558 		JBrowse link
G Ndfip1 Nedd4 family interacting protein 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of NDFIP1 mRNA CTD PMID:21148743 NCBI chr18:30,265,808...30,316,068
Ensembl chr18:30,250,613...30,322,311 		JBrowse link
G Ndp norrin cystine knot growth factor NDP increases expression ISO Asbestos, Serpentine results in increased expression of NDP mRNA CTD PMID:21148743 NCBI chr  X:5,796,487...5,820,934
Ensembl chr  X:5,796,487...5,820,934 		JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO Asbestos, Serpentine results in increased expression of NDRG1 mRNA CTD PMID:29523930 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880 		JBrowse link
G Nebl nebulette decreases methylation ISO Asbestos, Serpentine results in decreased methylation of NEBL gene CTD PMID:29523930 NCBI chr17:80,113,891...80,466,331
Ensembl chr17:80,118,543...80,466,210 		JBrowse link
G Neu1 neuraminidase 1 increases expression ISO Asbestos, Serpentine results in increased expression of NEU1 mRNA CTD PMID:29523930 NCBI chr20:3,897,480...3,901,745
Ensembl chr20:3,897,480...3,901,745 		JBrowse link
G Neurod2 neuronal differentiation 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of NEUROD2 5' UTR CTD PMID:29523930 NCBI chr10:83,323,801...83,327,986
Ensembl chr10:83,324,442...83,327,986 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 increases expression ISO Asbestos, Serpentine results in increased expression of NFATC2 mRNA CTD PMID:24160326 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfix nuclear factor I X decreases methylation ISO Asbestos, Serpentine results in decreased methylation of NFIX promoter CTD PMID:29626692 NCBI chr19:23,355,388...23,450,360
Ensembl chr19:23,355,498...23,448,265 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 affects expression
increases expression		 ISO Asbestos, Serpentine affects the expression of NFKB1 mRNA
Asbestos, Serpentine results in increased expression of NFKB1 mRNA		 CTD PMID:10541885 PMID:24160326 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 affects expression ISO Asbestos, Serpentine affects the expression of NFKB2 mRNA CTD PMID:24160326 NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha affects expression ISO Asbestos, Serpentine affects the expression of NFKBIA mRNA CTD PMID:24160326 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbid NFKB inhibitor delta decreases methylation ISO Asbestos, Serpentine results in decreased methylation of NFKBID promoter CTD PMID:29626692 NCBI chr 1:85,679,353...85,690,415
Ensembl chr 1:85,680,861...85,690,447 		JBrowse link
G Nfkbiz NFKB inhibitor zeta affects expression ISO Asbestos, Serpentine affects the expression of NFKBIZ mRNA CTD PMID:24160326 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nhsl1 NHS-like 1 increases expression ISO Asbestos, Serpentine results in increased expression of NHSL1 mRNA CTD PMID:21148743 NCBI chr 1:12,956,525...13,188,580
Ensembl chr 1:12,956,021...13,187,547 		JBrowse link
G Nin ninein increases expression ISO Asbestos, Serpentine results in increased expression of NIN mRNA CTD PMID:21148743 NCBI chr 6:88,525,405...88,627,710
Ensembl chr 6:88,525,742...88,627,639 		JBrowse link
G Nkx3-1 NK3 homeobox 1 affects expression ISO Asbestos, Serpentine affects the expression of NKX3-1 mRNA CTD PMID:24160326 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441 		JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO NLRP3 protein affects the reaction [Asbestos, Serpentine results in increased expression of CXCL1 protein]; NLRP3 protein affects the reaction [Asbestos, Serpentine results in increased expression of IL1B protein] CTD PMID:18403674 NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811 		JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO Asbestos, Serpentine results in increased expression of NOS1 mRNA CTD PMID:21148743 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions		 EXP
ISO		 Asbestos, Serpentine results in increased expression of NOS2 mRNA
[Asbestos, Serpentine co-treated with IL1B protein] results in increased expression of NOS2 mRNA; [Asbestos, Serpentine co-treated with IL1B protein] results in increased expression of NOS2 protein		 CTD PMID:9400719 PMID:9698594 PMID:9826428 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notum NOTUM, palmitoleoyl-protein carboxylesterase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of NOTUM 3' UTR CTD PMID:29523930 NCBI chr10:105,933,245...105,940,327
Ensembl chr10:105,933,249...105,940,315 		JBrowse link
G Npc1 NPC intracellular cholesterol transporter 1 increases expression ISO Asbestos, Serpentine results in increased expression of NPC1 mRNA CTD PMID:29523930 NCBI chr18:3,379,482...3,425,100
Ensembl chr18:3,379,482...3,425,049 		JBrowse link
G Nppb natriuretic peptide B decreases expression ISO Asbestos, Serpentine results in decreased expression of NPPB mRNA CTD PMID:24160326 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Nptx1 neuronal pentraxin 1 increases expression ISO Asbestos, Serpentine results in increased expression of NPTX1 mRNA CTD PMID:29523930 NCBI chr10:104,811,107...104,820,358
Ensembl chr10:104,811,403...104,820,367 		JBrowse link
G Nr4a2 nuclear receptor subfamily 4, group A, member 2 increases expression ISO Asbestos, Serpentine results in increased expression of NR4A2 mRNA CTD PMID:24160326 NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877 		JBrowse link
G Nrcam neuronal cell adhesion molecule increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of NRCAM mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of NRCAM mRNA]		 CTD PMID:21514415 NCBI chr 6:61,402,813...61,698,536
Ensembl chr 6:61,329,863...61,702,992 		JBrowse link
G Nrep neuronal regeneration related protein decreases expression ISO Asbestos, Serpentine results in decreased expression of NREP mRNA CTD PMID:29523930 NCBI chr18:25,017,069...25,046,593
Ensembl chr18:25,017,083...25,046,591 		JBrowse link
G Nrg1 neuregulin 1 affects expression ISO Asbestos, Serpentine affects the expression of NRG1 mRNA CTD PMID:24160326 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Nrip2 nuclear receptor interacting protein 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of NRIP2 5' UTR CTD PMID:29523930 NCBI chr 4:161,673,964...161,684,055
Ensembl chr 4:161,639,356...161,684,070 		JBrowse link
G Nrp1 neuropilin 1 increases expression ISO Asbestos, Serpentine results in increased expression of NRP1 mRNA CTD PMID:29523930 NCBI chr19:56,359,455...56,514,628
Ensembl chr19:56,359,455...56,513,633 		JBrowse link
G Nrxn3 neurexin 3 increases methylation ISO Asbestos, Serpentine results in increased methylation of NRXN3 gene CTD PMID:29523930 NCBI chr 6:107,641,760...109,272,849
Ensembl chr 6:107,641,780...109,272,044 		JBrowse link
G Nuf2 NUF2 component of NDC80 kinetochore complex increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of NUF2 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of NUF2 mRNA]		 CTD PMID:21514415 NCBI chr13:81,693,675...81,722,765
Ensembl chr13:81,693,598...81,722,766 		JBrowse link
G Nup50 nucleoporin 50 increases methylation ISO Asbestos, Serpentine results in increased methylation of NUP50 5' UTR CTD PMID:29523930 NCBI chr 7:116,047,960...116,065,231
Ensembl chr 7:116,048,021...116,066,905 		JBrowse link
G Nxph1 neurexophilin 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of NXPH1 gene CTD PMID:29523930 NCBI chr 4:36,998,068...37,311,135
Ensembl chr 4:36,997,669...37,311,132 		JBrowse link
G Oas1a 2'-5' oligoadenylate synthetase 1A increases expression ISO Asbestos, Serpentine results in increased expression of OAS1 mRNA CTD PMID:24160326 NCBI chr12:35,669,798...35,680,505
Ensembl chr12:35,669,801...35,680,517 		JBrowse link
G Oas2 2'-5' oligoadenylate synthetase 2 increases expression ISO Asbestos, Serpentine results in increased expression of OAS2 mRNA CTD PMID:24160326 NCBI chr12:35,802,824...35,830,778
Ensembl chr12:35,806,759...35,829,371 		JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 increases expression ISO Asbestos, Serpentine results in increased expression of OAS3 mRNA CTD PMID:24160326 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781 		JBrowse link
G Oasl 2'-5'-oligoadenylate synthetase-like increases expression
decreases expression		 ISO Asbestos, Serpentine results in increased expression of OASL mRNA
Asbestos, Serpentine results in decreased expression of OASL mRNA		 CTD PMID:24160326 PMID:29523930 NCBI chr12:41,682,900...41,695,641
Ensembl chr12:41,682,900...41,695,641 		JBrowse link
G Ocln occludin decreases expression ISO Asbestos, Serpentine results in decreased expression of OCLN protein CTD PMID:30609805 NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150 		JBrowse link
G Ogn osteoglycin decreases expression ISO Asbestos, Serpentine results in decreased expression of OGN mRNA CTD PMID:16251409 NCBI chr17:15,032,069...15,052,626
Ensembl chr17:15,032,069...15,052,739 		JBrowse link
G Olfm2 olfactomedin 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of OLFM2 gene CTD PMID:29523930 NCBI chr 8:19,204,472...19,282,154
Ensembl chr 8:19,204,475...19,282,117 		JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO Asbestos, Serpentine results in increased expression of OLR1 mRNA CTD PMID:24160326 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523 		JBrowse link
G Onecut1 one cut homeobox 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ONECUT1 promoter CTD PMID:29626692 NCBI chr 8:75,599,432...75,633,598
Ensembl chr 8:75,599,740...75,627,277 		JBrowse link
G Or10al6 olfactory receptor family 10 subfamily AL member 6 decreases expression ISO Asbestos, Serpentine results in decreased expression of OR10AL6 mRNA CTD PMID:23917077 NCBI chr20:738,257...739,607
Ensembl chr20:734,965...811,125 		JBrowse link
G Or2h2c olfactory receptor family 2 subfamily H member 2C increases methylation ISO Asbestos, Serpentine results in increased methylation of OR2H2 exon CTD PMID:29523930 NCBI chr20:1,398,964...1,399,902
Ensembl chr20:1,395,108...1,400,441 		JBrowse link
G Otop1 otopetrin 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of OTOP1 mRNA CTD PMID:23917077 NCBI chr14:72,505,036...72,532,497
Ensembl chr14:72,503,592...72,532,497 		JBrowse link
G P4ha2 prolyl 4-hydroxylase subunit alpha 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of P4HA2 5' UTR CTD PMID:29523930 NCBI chr10:38,243,136...38,271,983
Ensembl chr10:38,243,139...38,287,314 		JBrowse link
G Panx1 Pannexin 1 affects expression ISO Asbestos, Serpentine affects the expression of PANX1 mRNA CTD PMID:24160326 NCBI chr 8:11,851,176...11,889,774
Ensembl chr 8:11,850,730...11,889,774 		JBrowse link
G Pappa pappalysin increases expression ISO Asbestos, Serpentine results in increased expression of PAPPA mRNA CTD PMID:24160326 NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666 		JBrowse link
G Parm1 prostate androgen-regulated mucin-like protein 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PARM1 mRNA CTD PMID:21148743 NCBI chr14:16,468,309...16,577,339
Ensembl chr14:16,468,459...16,577,314 		JBrowse link
G Pax2 paired box 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of PAX2 gene CTD PMID:29523930 NCBI chr 1:243,616,509...243,697,454
Ensembl chr 1:243,616,606...243,695,321 		JBrowse link
G Paxip1 PAX interacting protein 1 affects methylation ISO Asbestos, Serpentine affects the methylation of PAXIP1 gene CTD PMID:29523930 NCBI chr 4:7,525,132...7,576,659
Ensembl chr 4:7,525,004...7,576,548 		JBrowse link
G Pbk PDZ binding kinase increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of PBK mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of PBK mRNA]		 CTD PMID:21514415 NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014 		JBrowse link
G Pcdh9 protocadherin 9 increases methylation ISO Asbestos, Serpentine results in increased methylation of PCDH9 gene CTD PMID:29523930 NCBI chr15:69,340,108...70,237,531
Ensembl chr15:69,340,645...70,237,538 		JBrowse link
G Pcdha1 protocadherin alpha 1 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA1 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha10 protocadherin alpha 10 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA10 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha11 protocadherin alpha 11 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA11 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha12 protocadherin alpha 12 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA12 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha13 protocadherin alpha 13 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA13 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha2 protocadherin alpha 2 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA2 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha3 protocadherin alpha 3 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA3 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha4 protocadherin alpha 4 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA4 gene CTD PMID:29523930 NCBI chr18:28,581,040...28,846,214
Ensembl chr18:28,581,225...28,846,211 		JBrowse link
G Pcdha5 protocadherin alpha 5 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA5 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha6 protocadherin alpha 6 decreases expression
affects methylation		 ISO Asbestos, Serpentine results in decreased expression of PCDHA6 mRNA
Asbestos, Serpentine affects the methylation of PCDHA6 gene		 CTD PMID:16251409 PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha7 protocadherin alpha 7 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA7 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha8 protocadherin alpha 8 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA8 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdha9 protocadherin alpha 9 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHA9 gene CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdhac1 protocadherin alpha subfamily C, 1 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHAC1 gene CTD PMID:29523930 NCBI chr18:28,740,353...28,750,216
Ensembl chr18:28,581,225...28,846,211 		JBrowse link
G Pcdhac2 protocadherin alpha subfamily C, 2 affects methylation ISO Asbestos, Serpentine affects the methylation of PCDHAC2 5' UTR CTD PMID:29523930 Ensembl chr18:28,581,225...28,846,211 JBrowse link
G Pcdhga4 protocadherin gamma subfamily A, 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PCDHGA4 gene CTD PMID:29523930 NCBI chr18:29,508,152...29,543,103 JBrowse link
G Pcna proliferating cell nuclear antigen increases expression EXP Asbestos, Serpentine results in increased expression of PCNA mRNA; Asbestos, Serpentine results in increased expression of PCNA protein CTD PMID:8686744 PMID:9115760 NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995 		JBrowse link
G Pdgfa platelet derived growth factor subunit A increases expression
multiple interactions		 ISO
EXP		 Asbestos, Serpentine results in increased expression of PDGFA mRNA
[TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of PDGFA mRNA]
Asbestos, Serpentine results in increased expression of PDGFA mRNA; Asbestos, Serpentine results in increased expression of PDGFA protein		 CTD PMID:9271299 PMID:9846974 PMID:18039278 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497 		JBrowse link
G Pdgfb platelet derived growth factor subunit B increases expression
increases response to substance
decreases methylation		 ISO
EXP		 Asbestos, Serpentine results in increased expression of PDGFB mRNA
PDGFB protein results in increased susceptibility to Asbestos, Serpentine
Asbestos, Serpentine results in decreased methylation of PDGFB 5' UTR
Asbestos, Serpentine results in increased expression of PDGFB mRNA; Asbestos, Serpentine results in increased expression of PDGFB protein		 CTD PMID:9271299 PMID:15511213 PMID:18039278 PMID:29523930 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
G Pdgfra platelet derived growth factor receptor alpha decreases expression
increases expression		 ISO
EXP		 Asbestos, Serpentine results in decreased expression of PDGFRA mRNA
Asbestos, Serpentine results in increased expression of PDGFRA mRNA; Asbestos, Serpentine results in increased expression of PDGFRA protein		 CTD PMID:8392089 PMID:9603151 PMID:16251409 NCBI chr14:33,005,838...33,054,347
Ensembl chr14:33,005,839...33,054,335 		JBrowse link
G Pdp1 pyruvate dehydrogenase phosphatase catalytic subunit 1 increases expression ISO Asbestos, Serpentine results in increased expression of PDP1 mRNA CTD PMID:29523930 NCBI chr 5:25,446,843...25,455,107
Ensembl chr 5:25,446,272...25,455,217 		JBrowse link
G Pdzd2 PDZ domain containing 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of PDZD2 mRNA CTD PMID:29523930 NCBI chr 2:61,384,614...61,770,516
Ensembl chr 2:61,386,381...61,770,524 		JBrowse link
G Pea15 proliferation and apoptosis adaptor protein 15 increases expression ISO Asbestos, Serpentine results in increased expression of PEA15 mRNA CTD PMID:21148743 NCBI chr13:84,657,815...84,667,437
Ensembl chr13:84,654,870...84,667,499 		JBrowse link
G Phldb1 pleckstrin homology-like domain, family B, member 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PHLDB1 mRNA CTD PMID:29523930 NCBI chr 8:45,003,543...45,051,541
Ensembl chr 8:45,003,538...45,051,522 		JBrowse link
G Pid1 phosphotyrosine interaction domain containing 1 affects expression ISO Asbestos, Serpentine affects the expression of PID1 mRNA CTD PMID:24160326 NCBI chr 9:85,284,335...85,503,035
Ensembl chr 9:85,284,335...85,503,044 		JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO Asbestos, Serpentine results in increased expression of PIK3R5 mRNA CTD PMID:21148743 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374 		JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PIM1 promoter CTD PMID:29626692 NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174 		JBrowse link
G Pim3 Pim-3 proto-oncogene, serine/threonine kinase affects expression ISO Asbestos, Serpentine affects the expression of PIM3 mRNA CTD PMID:24160326 NCBI chr 7:119,953,377...119,956,587
Ensembl chr 7:119,953,175...119,956,587 		JBrowse link
G Plau plasminogen activator, urokinase increases expression ISO Asbestos, Serpentine results in increased expression of PLAU mRNA CTD PMID:9853007 PMID:23917077 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor increases expression ISO Asbestos, Serpentine results in increased expression of PLAUR mRNA; Asbestos, Serpentine results in increased expression of PLAUR protein CTD PMID:9853007 PMID:10536123 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Plcb2 phospholipase C, beta 2 increases expression ISO Asbestos, Serpentine results in increased expression of PLCB2 mRNA CTD PMID:21148743 NCBI chr 3:105,683,676...105,704,384
Ensembl chr 3:105,684,815...105,704,302 		JBrowse link
G Plekhg2 pleckstrin homology and RhoGEF domain containing G2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PLEKHG2 promoter CTD PMID:29626692 NCBI chr 1:83,651,902...83,665,063
Ensembl chr 1:83,647,748...83,665,063 		JBrowse link
G Plin2 perilipin 2 increases expression ISO Asbestos, Serpentine results in increased expression of PLIN2 mRNA CTD PMID:29523930 NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319 		JBrowse link
G Plk1 polo-like kinase 1 increases expression ISO Asbestos, Serpentine results in increased expression of PLK1 mRNA CTD PMID:24160326 NCBI chr 1:176,716,420...176,726,400
Ensembl chr 1:176,716,420...176,726,400 		JBrowse link
G Plpp3 phospholipid phosphatase 3 affects expression ISO Asbestos, Serpentine affects the expression of PLPP3 mRNA CTD PMID:24160326 NCBI chr 5:119,927,085...120,002,206
Ensembl chr 5:119,927,085...120,002,205 		JBrowse link
G Plxnb2 plexin B2 increases expression ISO Asbestos, Serpentine results in increased expression of PLXNB2 mRNA CTD PMID:16251409 NCBI chr 7:120,232,276...120,258,385
Ensembl chr 7:120,232,331...120,258,330 		JBrowse link
G Pmp2 peripheral myelin protein 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of PMP2 5' UTR CTD PMID:29523930 NCBI chr 2:91,611,334...91,615,252
Ensembl chr 2:91,611,334...91,615,252 		JBrowse link
G Poglut2 protein O-glucosyltransferase 2 increases expression ISO Asbestos, Serpentine results in increased expression of POGLUT2 mRNA CTD PMID:33581214 NCBI chr 9:46,256,388...46,268,714
Ensembl chr 9:46,256,390...46,268,532 		JBrowse link
G Potefam1 POTE ankyrin domain family member 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ANKRD30A promoter CTD PMID:29626692 NCBI chr 3:97,641,258...97,826,965
Ensembl chr 3:97,641,261...97,826,949 		JBrowse link
G Pou2f2 POU class 2 homeobox 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of POU2F2 promoter CTD PMID:29626692 NCBI chr 1:80,682,330...80,769,756
Ensembl chr 1:80,685,741...80,724,261 		JBrowse link
G Ppm1f protein phosphatase, Mg2+/Mn2+ dependent, 1F increases expression ISO Asbestos, Serpentine results in increased expression of PPM1F mRNA CTD PMID:21148743 NCBI chr11:84,064,422...84,094,410
Ensembl chr11:84,064,420...84,094,340 		JBrowse link
G Ppp1r12c protein phosphatase 1, regulatory subunit 12C decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PPP1R12C promoter CTD PMID:29626692 NCBI chr 1:69,320,240...69,343,200
Ensembl chr 1:69,320,255...69,343,200 		JBrowse link
G Ppp1r16b protein phosphatase 1, regulatory subunit 16B decreases expression ISO Asbestos, Serpentine results in decreased expression of PPP1R16B mRNA CTD PMID:21148743 NCBI chr 3:147,323,652...147,419,658
Ensembl chr 3:147,324,126...147,418,937 		JBrowse link
G Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PPP2R2A gene CTD PMID:29523930 NCBI chr15:41,204,659...41,263,924
Ensembl chr15:41,204,200...41,263,924 		JBrowse link
G Ppp6r1 protein phosphatase 6, regulatory subunit 1 increases expression ISO Asbestos, Serpentine results in increased expression of PPP6R1 mRNA CTD PMID:21148743 NCBI chr 1:69,190,856...69,217,598
Ensembl chr 1:69,189,822...69,216,272 		JBrowse link
G Prag1 PEAK1 related kinase activating pseudokinase 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PRAG1 mRNA CTD PMID:29523930 NCBI chr16:56,087,885...56,141,153
Ensembl chr16:56,087,885...56,141,153 		JBrowse link
G Prdm1 PR/SET domain 1 increases expression ISO Asbestos, Serpentine results in increased expression of PRDM1 mRNA CTD PMID:24160326 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PREX1 mRNA CTD PMID:21148743 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Prf1 perforin 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PRF1 protein CTD PMID:19822075 NCBI chr20:29,246,202...29,251,712
Ensembl chr20:29,246,202...29,251,701 		JBrowse link
G Prkaa2 protein kinase AMP-activated catalytic subunit alpha 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PRKAA2 promoter CTD PMID:29626692 NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543 		JBrowse link
G Prkaca protein kinase cAMP-activated catalytic subunit alpha decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PRKACA 3' UTR CTD PMID:29523930 NCBI chr19:24,155,081...24,178,430
Ensembl chr19:24,155,090...24,178,430 		JBrowse link
G Prkcb protein kinase C, beta decreases expression ISO Asbestos, Serpentine results in decreased expression of PRKCB mRNA CTD PMID:21148743 NCBI chr 1:176,832,173...177,163,539
Ensembl chr 1:176,832,226...177,163,536 		JBrowse link
G Prkcd protein kinase C, delta multiple interactions
decreases response to substance		 ISO Asbestos, Serpentine promotes the reaction [PRKCD protein binds to PRKD1 protein]; PRKCD protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of PRKD1 protein]
PRKCD gene mutant form results in decreased susceptibility to Asbestos, Serpentine		 CTD PMID:19116364 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Prkcsh PRKCSH beta subunit of glucosidase II increases expression ISO Asbestos, Serpentine results in increased expression of PRKCSH mRNA CTD PMID:29523930 NCBI chr 8:20,534,787...20,546,493
Ensembl chr 8:20,534,880...20,546,492 		JBrowse link
G Prkd1 protein kinase D1 multiple interactions
increases phosphorylation		 ISO Asbestos, Serpentine promotes the reaction [MAPK1 protein binds to PRKD1 protein]; Asbestos, Serpentine promotes the reaction [MAPK3 protein binds to PRKD1 protein]; Asbestos, Serpentine promotes the reaction [PRKCD protein binds to PRKD1 protein]; PRKCD protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of PRKD1 protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of BCL2L11 protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased expression of and results in increased phosphorylation of JUN protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK1 protein]; PRKD1 protein affects the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK3 protein] CTD PMID:19116364 NCBI chr 6:67,725,193...68,039,002
Ensembl chr 6:67,725,905...68,039,042 		JBrowse link
G Prkdc protein kinase, DNA-activated, catalytic subunit multiple interactions ISO PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL2 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL3 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CCL5 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CSF2 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of CXCL1 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL10 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL13 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL4 protein]; PRKDC affects the reaction [Asbestos, Serpentine results in increased expression of IL5 protein]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of IL4 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MKI67 protein]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP12 mRNA]; PRKDC protein affects the reaction [Asbestos, Serpentine results in increased expression of MMP13 mRNA] CTD PMID:16571779 PMID:17200189 NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952 		JBrowse link
G Prrx1 paired related homeobox 1 affects expression ISO Asbestos, Serpentine affects the expression of PRRX1 mRNA CTD PMID:24160326 NCBI chr13:75,600,777...75,671,896
Ensembl chr13:75,601,706...75,670,866 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 increases expression ISO Asbestos, Serpentine results in increased expression of PSMB9 mRNA CTD PMID:24160326 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Ptges prostaglandin E synthase increases expression ISO Asbestos, Serpentine results in increased expression of PTGES mRNA CTD PMID:24160326 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Ptges3 prostaglandin E synthase 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of PTGES3 gene CTD PMID:29523930 NCBI chr 7:490,698...507,759
Ensembl chr 7:490,656...508,084 		JBrowse link
G Ptgr3 prostaglandin reductase 3 increases expression
increases methylation		 ISO Asbestos, Serpentine results in increased expression of PTGR3 mRNA
Asbestos, Serpentine results in increased methylation of PTGR3 gene		 CTD PMID:21148743 PMID:29523930 NCBI chr18:77,454,435...77,463,785
Ensembl chr18:77,454,435...77,463,785 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO Asbestos, Serpentine results in increased expression of PTGS2 mRNA CTD PMID:24160326 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptprn protein tyrosine phosphatase, receptor type, N increases expression ISO Asbestos, Serpentine results in increased expression of PTPRN mRNA CTD PMID:24160326 NCBI chr 9:76,741,010...76,756,704
Ensembl chr 9:76,741,016...76,756,190 		JBrowse link
G Ptprn2 protein tyrosine phosphatase, receptor type N2 increases methylation
decreases methylation		 ISO Asbestos, Serpentine results in increased methylation of PTPRN2 gene
Asbestos, Serpentine results in decreased methylation of PTPRN2 gene		 CTD PMID:29523930 NCBI chr 6:137,439,572...138,191,575
Ensembl chr 6:137,439,540...138,191,575 		JBrowse link
G Ptx3 pentraxin 3 increases expression ISO Asbestos, Serpentine results in increased expression of PTX3 mRNA CTD PMID:21148743 NCBI chr 2:150,487,513...150,493,323
Ensembl chr 2:150,487,513...150,493,323 		JBrowse link
G Pxylp1 2-phosphoxylose phosphatase 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of PXYLP1 mRNA CTD PMID:21148743 NCBI chr 8:97,419,766...97,485,163
Ensembl chr 8:97,419,776...97,485,064 		JBrowse link
G Rac1 Rac family small GTPase 1 increases activity
multiple interactions
decreases response to substance		 ISO Asbestos, Serpentine results in increased activity of RAC1 protein
RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein]
RAC1 gene mutant form results in decreased susceptibility to Asbestos, Serpentine
RAC1 protein affects the reaction [Asbestos, Serpentine results in increased expression of TNF mRNA]; RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein]		 CTD PMID:19684199 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein increases expression ISO Asbestos, Serpentine results in increased expression of RAP1GAP mRNA CTD PMID:21148743 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253 		JBrowse link
G Raph1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 increases expression ISO Asbestos, Serpentine results in increased expression of RAPH1 mRNA CTD PMID:21148743 NCBI chr 9:61,907,476...61,990,170
Ensembl chr 9:61,907,758...61,961,209 		JBrowse link
G Rasa3 RAS p21 protein activator 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RASA3 gene CTD PMID:29523930 NCBI chr16:75,855,360...75,969,349
Ensembl chr16:75,855,265...75,970,804 		JBrowse link
G Rbfox1 RNA binding fox-1 homolog 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of RBFOX1 gene CTD PMID:29523930 NCBI chr10:8,152,198...10,248,120
Ensembl chr10:8,152,198...9,686,659 		JBrowse link
G Rbm12b RNA binding motif protein 12B decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RBM12B promoter CTD PMID:29626692 NCBI chr 5:25,597,405...25,610,324
Ensembl chr 5:25,590,493...25,611,245 		JBrowse link
G Rbm22 RNA binding motif protein 22 increases expression ISO Asbestos, Serpentine results in increased expression of RBM22 mRNA CTD PMID:21148743 NCBI chr18:54,013,374...54,024,182
Ensembl chr18:54,013,351...54,024,569 		JBrowse link
G Rbm27 RNA binding motif protein 27 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RBM27 promoter CTD PMID:29626692 NCBI chr18:34,273,527...34,336,124
Ensembl chr18:34,273,527...34,334,126 		JBrowse link
G Rbm44 RNA binding motif protein 44 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RBM44 promoter CTD PMID:29626692 NCBI chr 9:91,731,153...91,756,783
Ensembl chr 9:91,731,115...91,756,772 		JBrowse link
G Rbms1 RNA binding motif, single stranded interacting protein 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of RBMS1 gene CTD PMID:29523930 NCBI chr 3:45,195,828...45,420,406
Ensembl chr 3:45,197,972...45,420,376 		JBrowse link
G Rdx radixin decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RDX 5' UTR CTD PMID:29523930 NCBI chr 8:52,379,494...52,437,673
Ensembl chr 8:52,379,494...52,437,678 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [Asbestos, Serpentine results in increased secretion of IL1B protein] which results in increased phosphorylation of RELA protein CTD PMID:23017228 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Rfk riboflavin kinase increases expression ISO Asbestos, Serpentine results in increased expression of RFK mRNA CTD PMID:21148743 NCBI chr 1:214,799,880...214,807,440
Ensembl chr 1:214,799,825...214,807,438
Ensembl chr  X:214,799,825...214,807,438 		JBrowse link
G Rflnb refilin B increases expression ISO Asbestos, Serpentine results in increased expression of RFLNB mRNA CTD PMID:33581214 NCBI chr10:60,893,693...60,899,970
Ensembl chr10:60,893,713...60,899,976 		JBrowse link
G Rgcc regulator of cell cycle decreases expression ISO Asbestos, Serpentine results in decreased expression of RGCC mRNA CTD PMID:21148743 NCBI chr15:54,662,483...54,675,320
Ensembl chr15:54,662,483...54,681,141 		JBrowse link
G Rhbdl3 rhomboid like 3 increases methylation ISO Asbestos, Serpentine results in increased methylation of RHBDL3 gene CTD PMID:29523930 NCBI chr10:65,299,250...65,354,099
Ensembl chr10:65,299,194...65,354,099 		JBrowse link
G Rims3 regulating synaptic membrane exocytosis 3 increases expression ISO Asbestos, Serpentine results in increased expression of RIMS3 mRNA CTD PMID:21148743 NCBI chr 5:134,429,092...134,468,935
Ensembl chr 5:134,435,829...134,640,489 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 affects expression ISO Asbestos, Serpentine affects the expression of RIPK2 mRNA CTD PMID:24160326 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Ripk3 receptor-interacting serine-threonine kinase 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of RIPK3 promoter CTD PMID:29626692 NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121 		JBrowse link
G Rnase1 ribonuclease A family member 1, pancreatic decreases expression ISO Asbestos, Serpentine results in decreased expression of RNASE1 mRNA CTD PMID:21148743 NCBI chr15:24,361,924...24,363,633
Ensembl chr15:24,361,927...24,363,624 		JBrowse link
G Rnase2 ribonuclease A family member 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of RNASE2 mRNA CTD PMID:24160326 NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479 		JBrowse link
G Rnf19b ring finger protein 19B affects expression ISO Asbestos, Serpentine affects the expression of RNF19B mRNA CTD PMID:24160326 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 decreases phosphorylation ISO Asbestos, Serpentine results in decreased phosphorylation of RPS6KB1 protein CTD PMID:24735948 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Rrm2 ribonucleotide reductase regulatory subunit M2 increases expression ISO Asbestos, Serpentine results in increased expression of RRM2 mRNA CTD PMID:24160326 NCBI chr 6:41,339,858...41,346,774
Ensembl chr 6:41,340,557...41,346,773 		JBrowse link
G Rsad2 radical S-adenosyl methionine domain containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of RSAD2 mRNA CTD PMID:24160326 NCBI chr 6:43,046,514...43,059,737
Ensembl chr 6:43,047,658...43,059,699 		JBrowse link
G Rsph1 radial spoke head component 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of RSPH1 mRNA CTD PMID:21148743 NCBI chr20:9,341,910...9,360,640
Ensembl chr20:9,341,913...9,360,640 		JBrowse link
G Runx1 RUNX family transcription factor 1 increases expression
decreases expression		 ISO Asbestos, Serpentine results in increased expression of RUNX1 mRNA
Asbestos, Serpentine results in decreased expression of RUNX1 mRNA		 CTD PMID:21148743 PMID:23917077 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G S100a16 S100 calcium binding protein A16 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of S100A16 5' UTR CTD PMID:29523930 NCBI chr 2:176,016,405...176,022,117
Ensembl chr 2:176,016,268...176,022,117 		JBrowse link
G Satb1 SATB homeobox 1 increases expression ISO Asbestos, Serpentine results in increased expression of SATB1 mRNA CTD PMID:21148743 NCBI chr 9:4,677,817...4,773,061
Ensembl chr 9:4,680,920...4,753,251 		JBrowse link
G Satb2 SATB homeobox 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SATB2 promoter CTD PMID:29626692 NCBI chr 9:58,348,027...58,534,256
Ensembl chr 9:58,350,246...58,530,707 		JBrowse link
G Scg2 secretogranin II increases expression ISO Asbestos, Serpentine results in increased expression of SCG2 mRNA CTD PMID:29523930 NCBI chr 9:80,803,074...80,808,646
Ensembl chr 9:80,803,075...80,821,097 		JBrowse link
G Sema6a semaphorin 6A decreases expression ISO Asbestos, Serpentine results in decreased expression of SEMA6A mRNA CTD PMID:21148743 NCBI chr18:40,050,623...40,171,954
Ensembl chr18:40,050,624...40,171,954 		JBrowse link
G Septin1 septin 1 increases expression ISO Asbestos, Serpentine results in increased expression of SEPTIN1 mRNA CTD PMID:21148743 NCBI chr 1:181,832,700...181,836,566
Ensembl chr 1:181,832,701...181,836,566 		JBrowse link
G Septin4 septin 4 decreases expression ISO Asbestos, Serpentine results in decreased expression of SEPTIN4 mRNA CTD PMID:29523930 NCBI chr10:72,366,729...72,390,764
Ensembl chr10:72,366,873...72,390,768 		JBrowse link
G Serp2 stress-associated endoplasmic reticulum protein family member 2 increases expression ISO Asbestos, Serpentine results in increased expression of SERP2 mRNA CTD PMID:21148743 NCBI chr15:51,879,882...51,903,958
Ensembl chr15:51,879,877...51,904,785 		JBrowse link
G Serpine1 serpin family E member 1 decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of SERPINE1 mRNA
Asbestos, Serpentine results in increased expression of SERPINE1 mRNA		 CTD PMID:23917077 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Sertm1 serine-rich and transmembrane domain containing 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of SERTM1 5' UTR CTD PMID:29523930 NCBI chr 2:139,086,905...139,106,528
Ensembl chr 2:139,086,908...139,106,459 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of SFRP1 mRNA CTD PMID:21148743 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sfswap splicing factor SWAP decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SFSWAP gene CTD PMID:29523930 NCBI chr12:27,109,607...27,179,941
Ensembl chr12:27,109,611...27,179,884 		JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SGK1 promoter CTD PMID:29626692 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283 		JBrowse link
G Shank3 SH3 and multiple ankyrin repeat domains 3 increases methylation ISO Asbestos, Serpentine results in increased methylation of SHANK3 5' UTR CTD PMID:29523930 NCBI chr 7:120,568,707...120,630,796
Ensembl chr 7:120,570,402...120,630,374 		JBrowse link
G Siglecl1 SIGLEC family like 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SIGLECL1 3' UTR CTD PMID:29523930 NCBI chr 1:93,916,971...93,924,742
Ensembl chr 1:93,900,773...93,913,028
Ensembl chr 1:93,900,773...93,913,028 		JBrowse link
G Slc10a1 solute carrier family 10 member 1 increases expression ISO Asbestos, Serpentine results in increased expression of SLC10A1 mRNA CTD PMID:21148743 NCBI chr 6:100,613,045...100,626,670
Ensembl chr 6:100,613,045...100,626,670 		JBrowse link
G Slc15a3 solute carrier family 15 member 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of SLC15A3 mRNA CTD PMID:21148743 NCBI chr 1:207,492,365...207,507,158
Ensembl chr 1:207,492,365...207,507,157 		JBrowse link
G Slc16a3 solute carrier family 16 member 3 increases expression ISO Asbestos, Serpentine results in increased expression of SLC16A3 mRNA CTD PMID:29523930 NCBI chr10:106,212,679...106,222,564
Ensembl chr10:106,212,778...106,222,562 		JBrowse link
G Slc1a5 solute carrier family 1 member 5 increases expression ISO Asbestos, Serpentine results in increased expression of SLC1A5 mRNA CTD PMID:29523930 NCBI chr 1:77,456,849...77,470,952
Ensembl chr 1:77,456,694...77,470,952 		JBrowse link
G Slc22a4 solute carrier family 22 member 4 increases expression ISO Asbestos, Serpentine results in increased expression of SLC22A4 mRNA CTD PMID:24160326 NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720 		JBrowse link
G Slc25a33 solute carrier family 25 member 33 increases methylation ISO Asbestos, Serpentine results in increased methylation of SLC25A33 gene CTD PMID:29523930 NCBI chr 5:160,195,040...160,219,961
Ensembl chr 5:160,195,042...160,219,961 		JBrowse link
G Slc25a37 solute carrier family 25 member 37 affects expression ISO Asbestos, Serpentine affects the expression of SLC25A37 mRNA CTD PMID:24160326 NCBI chr15:44,534,280...44,576,697
Ensembl chr15:44,536,727...44,577,199 		JBrowse link
G Slc26a7 solute carrier family 26 member 7 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SLC26A7 gene CTD PMID:29523930 NCBI chr 5:27,884,400...28,021,865
Ensembl chr 5:27,887,042...28,021,658 		JBrowse link
G Slc2a1 solute carrier family 2 member 1 increases expression ISO Asbestos, Serpentine results in increased expression of SLC2A1 mRNA CTD PMID:29523930 NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416 		JBrowse link
G Slc2a3 solute carrier family 2 member 3 increases expression ISO Asbestos, Serpentine results in increased expression of SLC2A3 mRNA CTD PMID:29523930 NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472 		JBrowse link
G Slc39a6 solute carrier family 39 member 6 increases expression ISO Asbestos, Serpentine results in increased expression of SLC39A6 mRNA CTD PMID:21148743 NCBI chr18:15,864,874...15,885,417
Ensembl chr18:15,864,875...15,885,417 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 increases expression ISO Asbestos, Serpentine results in increased expression of SLC3A2 mRNA CTD PMID:29523930 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Slc43a3 solute carrier family 43, member 3 increases expression ISO Asbestos, Serpentine results in increased expression of SLC43A3 mRNA CTD PMID:33581214 NCBI chr 3:70,008,160...70,030,324
Ensembl chr 3:70,009,313...70,029,749 		JBrowse link
G Slc45a4 solute carrier family 45, member 4 increases expression ISO Asbestos, Serpentine results in increased expression of SLC45A4 mRNA CTD PMID:21148743 NCBI chr 7:105,478,886...105,550,160
Ensembl chr 7:105,481,792...105,550,170 		JBrowse link
G Slc51b SLC51 subunit beta increases expression ISO Asbestos, Serpentine results in increased expression of SLC51B mRNA CTD PMID:21148743 NCBI chr 8:65,931,891...65,939,953
Ensembl chr 8:65,931,890...65,940,145 		JBrowse link
G Slc6a6 solute carrier family 6 member 6 decreases expression ISO Asbestos, Serpentine results in decreased expression of SLC6A6 mRNA CTD PMID:21148743 NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875 		JBrowse link
G Slc7a14 solute carrier family 7, member 14 increases methylation ISO Asbestos, Serpentine results in increased methylation of SLC7A14 gene CTD PMID:29523930 NCBI chr 2:112,065,286...112,171,319
Ensembl chr 2:112,065,286...112,171,313 		JBrowse link
G Slc7a2 solute carrier family 7 member 2 affects expression ISO Asbestos, Serpentine affects the expression of SLC7A2 mRNA CTD PMID:24160326 NCBI chr16:51,417,478...51,470,784
Ensembl chr16:51,417,493...51,470,784 		JBrowse link
G Slco1a4 solute carrier organic anion transporter family, member 1a4 increases methylation ISO Asbestos, Serpentine results in increased methylation of SLCO1A2 5' UTR CTD PMID:29523930 NCBI chr 4:174,710,004...174,764,810
Ensembl chr 4:174,710,004...175,254,573 		JBrowse link
G Slitrk3 SLIT and NTRK-like family, member 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SLITRK3 5' UTR CTD PMID:29523930 NCBI chr 2:157,680,067...157,697,404
Ensembl chr 2:157,687,535...157,696,709 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of SLPI mRNA
Asbestos, Serpentine results in increased expression of SLPI mRNA		 CTD PMID:24160326 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Slx4 SLX4 structure-specific endonuclease subunit decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SLX4 5' UTR CTD PMID:29523930 NCBI chr10:11,526,623...11,549,313
Ensembl chr10:11,528,424...11,549,295 		JBrowse link
G Smad2 SMAD family member 2 affects localization
multiple interactions
increases phosphorylation		 ISO Asbestos, Serpentine affects the localization of SMAD2 protein modified form
[Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased expression of SMAD2 mRNA; [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in increased phosphorylation of SMAD2 protein
Asbestos, Serpentine results in increased phosphorylation of SMAD2 protein		 CTD PMID:25358858 PMID:26685284 PMID:30609805 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions ISO [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of and results in increased phosphorylation of SMAD3 protein; [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of SMAD3 mRNA CTD PMID:25358858 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad7 SMAD family member 7 decreases expression ISO Asbestos, Serpentine results in decreased expression of SMAD7 mRNA CTD PMID:16251409 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smad9 SMAD family member 9 increases methylation ISO Asbestos, Serpentine results in increased methylation of SMAD9 5' UTR CTD PMID:29523930 NCBI chr 2:138,956,326...139,006,315
Ensembl chr 2:138,986,471...139,006,307 		JBrowse link
G Smim3 small integral membrane protein 3 affects expression ISO Asbestos, Serpentine affects the expression of SMIM3 mRNA CTD PMID:24160326 NCBI chr18:53,930,019...53,982,339
Ensembl chr18:53,930,020...53,957,416 		JBrowse link
G Smox spermine oxidase affects expression ISO Asbestos, Serpentine affects the expression of SMOX mRNA CTD PMID:24160326 NCBI chr 3:118,731,814...118,767,242
Ensembl chr 3:118,731,900...118,765,710 		JBrowse link
G Snai1 snail family transcriptional repressor 1 multiple interactions
affects localization
increases expression		 ISO 1,3-dihydro-1-(1-((4-(6-phenyl-1H-imidazo(4,5-g)quinoxalin-7-yl)phenyl)methyl)-4-piperidinyl)-2H-benzimidazol-2-one analog inhibits the reaction [Asbestos, Serpentine affects the localization of SNAI1 protein]; SB 216763 inhibits the reaction [Asbestos, Serpentine affects the localization of SNAI1 protein]
Asbestos, Serpentine results in increased expression of SNAI1 protein		 CTD PMID:26685284 PMID:30609805 NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969 		JBrowse link
G Snora12 small nucleolar RNA, H/ACA box 12 increases expression ISO Asbestos, Serpentine results in increased expression of SNORA12 mRNA CTD PMID:29523930 NCBI chr 1:243,001,398...243,001,540
Ensembl chr 1:243,001,398...243,001,540 		JBrowse link
G Snord13 small nucleolar RNA, C/D box 13 increases expression ISO Asbestos, Serpentine results in increased expression of SNORD13 mRNA CTD PMID:29523930 NCBI chr16:60,988,909...60,989,013
Ensembl chr16:60,988,909...60,989,013 		JBrowse link
G Snrpf small nuclear ribonucleoprotein polypeptide F increases methylation ISO Asbestos, Serpentine results in increased methylation of SNRPF 5' UTR CTD PMID:29523930 NCBI chr 7:28,130,427...28,137,129
Ensembl chr 7:28,130,427...28,137,129 		JBrowse link
G Snw1 SNW domain containing 1 increases expression ISO Asbestos, Serpentine results in increased expression of SNW1 mRNA CTD PMID:16251409 NCBI chr 6:107,095,450...107,119,536
Ensembl chr 6:107,095,457...107,119,536 		JBrowse link
G Snx7 sorting nexin 7 increases methylation ISO Asbestos, Serpentine results in increased methylation of SNX7 5' UTR CTD PMID:29523930 NCBI chr 2:205,843,164...205,927,737
Ensembl chr 2:205,842,837...205,927,763 		JBrowse link
G Snx9 sorting nexin 9 affects expression ISO Asbestos, Serpentine affects the expression of SNX9 mRNA CTD PMID:24160326 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression		 ISO Dithiothreitol inhibits the reaction [SOD1 protein affects the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]]; SOD1 protein affects the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]
Asbestos, Serpentine results in increased expression of SOD1 protein		 CTD PMID:26699812 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression ISO
EXP		 Asbestos, Serpentine results in increased expression of SOD2 mRNA; Asbestos, Serpentine results in increased expression of SOD2 protein CTD PMID:7677184 PMID:8118652 PMID:23017228 PMID:24160326 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sod3 superoxide dismutase 3 decreases expression ISO Asbestos, Serpentine results in decreased expression of SOD3 mRNA CTD PMID:16251409 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990 		JBrowse link
G Sorbs1 sorbin and SH3 domain containing 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of SORBS1 5' UTR CTD PMID:29523930 NCBI chr 1:239,107,882...239,330,276
Ensembl chr 1:239,108,777...239,330,169 		JBrowse link
G Sox2 SRY-box transcription factor 2 affects methylation ISO Asbestos, Serpentine affects the methylation of SOX2 exon CTD PMID:29523930 NCBI chr 2:117,536,929...117,539,340
Ensembl chr 2:117,536,929...117,539,338 		JBrowse link
G Sox4 SRY-box transcription factor 4 increases expression ISO Asbestos, Serpentine results in increased expression of SOX4 mRNA CTD PMID:16251409 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Sparc secreted protein acidic and cysteine rich decreases expression ISO Asbestos, Serpentine results in decreased expression of SPARC mRNA CTD PMID:21148743 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Sphk1 sphingosine kinase 1 increases expression ISO Asbestos, Serpentine results in increased expression of SPHK1 mRNA CTD PMID:29523930 NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240 		JBrowse link
G Spink13 serine peptidase inhibitor Kazal type 13 decreases expression ISO Asbestos, Serpentine results in decreased expression of SPINK13 mRNA CTD PMID:21148743 NCBI chr18:56,064,839...56,206,257
Ensembl chr18:56,064,839...56,206,257 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression
multiple interactions
decreases response to substance		 ISO Asbestos, Serpentine results in increased expression of SPP1 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of BPIFA1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of CYP2A4 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of FMO3 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of HAMP mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of HLF mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MB mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYL7 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYOZ2 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of MYRIP mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of SULT1D1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of TCAP mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of THRSP mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of ADAMTS2 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of AREG mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CCL3 protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CCL4 protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CKAP2 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of COL1A2 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of COL3A1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of CXCL10 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of ELN mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL12B protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL1B protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL4 protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of IL6 protein]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of NRCAM mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of NUF2 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of PBK mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of STBD1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of THBS1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TNC mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TSP1 mRNA]; SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of VCAN mRNA]; SPP1 gene mutant form promotes the reaction [Asbestos, Serpentine results in decreased expression of CCL11 protein]
SPP1 gene mutant form results in decreased susceptibility to Asbestos, Serpentine		 CTD PMID:16251409 PMID:21514415 PMID:23917077 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sprr2a small proline rich protein 2A increases expression ISO Asbestos, Serpentine results in increased expression of SPRR2A mRNA CTD PMID:16251409 NCBI chr 2:177,815,964...177,816,236
Ensembl chr 2:177,815,964...177,816,236 		JBrowse link
G Spty2d1 SPT2 chromatin protein domain containing 1 increases expression ISO Asbestos, Serpentine results in increased expression of SPTY2D1 mRNA CTD PMID:21148743 NCBI chr 1:97,531,495...97,549,616
Ensembl chr 1:97,531,508...97,549,581 		JBrowse link
G Srgn serglycin increases expression ISO Asbestos, Serpentine results in increased expression of SRGN mRNA CTD PMID:29523930 NCBI chr20:30,442,810...30,479,549
Ensembl chr20:30,442,813...30,457,406 		JBrowse link
G Ssr2 signal sequence receptor subunit 2 increases expression ISO Asbestos, Serpentine results in increased expression of SSR2 mRNA CTD PMID:21148743 NCBI chr 2:174,048,291...174,057,043
Ensembl chr 2:174,048,460...174,057,042 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Asbestos, Serpentine results in decreased expression of ST3GAL5 mRNA CTD PMID:24160326 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558 		JBrowse link
G Stag3 STAG3 cohesin complex component decreases expression ISO Asbestos, Serpentine results in decreased expression of STAG3 mRNA CTD PMID:21148743 NCBI chr12:17,284,677...17,314,936
Ensembl chr12:17,284,794...17,314,935 		JBrowse link
G Stambp Stam binding protein increases expression ISO Asbestos, Serpentine results in increased expression of STAMBP mRNA CTD PMID:21148743 NCBI chr 4:116,055,563...116,083,563
Ensembl chr 4:116,056,057...116,080,543 		JBrowse link
G Stard13 StAR-related lipid transfer domain containing 13 increases expression ISO Asbestos, Serpentine results in increased expression of STARD13 mRNA CTD PMID:21148743 NCBI chr12:566,282...959,372
Ensembl chr12:566,310...959,421 		JBrowse link
G Stat4 signal transducer and activator of transcription 4 increases expression ISO Asbestos, Serpentine results in increased expression of STAT4 mRNA CTD PMID:24160326 NCBI chr 9:49,472,660...49,588,540
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
increases oxidation		 ISO Asbestos, Serpentine promotes the reaction [Polyethylene Glycols results in increased oxidation of STAT6 protein]; Asbestos, Serpentine promotes the reaction [STAT6 protein binds to KDM6B promoter]; Asbestos, Serpentine results in increased oxidation of and results in increased phosphorylation of STAT6 protein; Dithiothreitol inhibits the reaction [Asbestos, Serpentine promotes the reaction [polyethylene glycol-superoxide dismutase results in increased oxidation of STAT6 protein]]; Dithiothreitol inhibits the reaction [Asbestos, Serpentine promotes the reaction [Polyethylene Glycols results in increased oxidation of STAT6 protein]]; Dithiothreitol inhibits the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]; Dithiothreitol inhibits the reaction [SOD1 protein affects the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]]; leflunomide inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of STAT6 protein]; polyethylene glycol-superoxide dismutase affects the reaction [STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF mRNA]]; SOD1 protein affects the reaction [Asbestos, Serpentine results in increased oxidation of STAT6 protein]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of CHIL3 mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of CHIL3 protein]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of KDM6B mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of RETNLA mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TGFB1 protein]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF protein] CTD PMID:26699812 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Stbd1 starch binding domain 1 multiple interactions
increases expression		 ISO SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of STBD1 mRNA] CTD PMID:21514415 NCBI chr14:15,470,452...15,473,857
Ensembl chr14:15,469,582...15,477,443 		JBrowse link
G Stc2 stanniocalcin 2 increases expression ISO Asbestos, Serpentine results in increased expression of STC2 mRNA CTD PMID:29523930 NCBI chr10:16,251,046...16,260,815
Ensembl chr10:16,250,853...16,262,973 		JBrowse link
G Steap4 STEAP4 metalloreductase decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of STEAP4 mRNA
Asbestos, Serpentine results in increased expression of STEAP4 mRNA		 CTD PMID:24160326 NCBI chr 4:26,077,182...26,099,859
Ensembl chr 4:26,054,671...26,099,859 		JBrowse link
G Stk24 serine/threonine kinase 24 increases methylation ISO Asbestos, Serpentine results in increased methylation of STK24 gene CTD PMID:29523930 NCBI chr15:98,363,707...98,458,940
Ensembl chr15:98,365,791...98,460,553 		JBrowse link
G Stk32c serine/threonine kinase 32C increases methylation ISO Asbestos, Serpentine results in increased methylation of STK32C gene CTD PMID:29523930 NCBI chr 1:193,900,718...193,981,723
Ensembl chr 1:193,900,718...193,981,723 		JBrowse link
G Stom stomatin decreases expression ISO Asbestos, Serpentine results in decreased expression of STOM mRNA CTD PMID:21148743 NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354 		JBrowse link
G Styk1 serine/threonine/tyrosine kinase 1 increases expression ISO Asbestos, Serpentine results in increased expression of STYK1 mRNA CTD PMID:23917077 NCBI chr 4:165,047,613...165,097,890
Ensembl chr 4:165,048,440...165,096,440 		JBrowse link
G Suco SUN domain containing ossification factor decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SUCO 5' UTR CTD PMID:29523930 NCBI chr13:74,192,808...74,257,896
Ensembl chr13:74,193,573...74,257,896 		JBrowse link
G Sulf2 sulfatase 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of SULF2 mRNA CTD PMID:29523930 NCBI chr 3:154,822,079...154,904,566
Ensembl chr 3:154,822,085...154,904,415 		JBrowse link
G Susd6 sushi domain containing 6 affects expression ISO Asbestos, Serpentine affects the expression of SUSD6 mRNA CTD PMID:24160326 NCBI chr 6:100,437,834...100,531,621
Ensembl chr 6:100,437,642...100,531,606 		JBrowse link
G Sync syncoilin, intermediate filament protein decreases methylation ISO Asbestos, Serpentine results in decreased methylation of SYNC 5' UTR CTD PMID:29523930 NCBI chr 5:141,631,837...141,656,184
Ensembl chr 5:141,632,367...141,688,659 		JBrowse link
G Tbr1 T-box brain transcription factor 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TBR1 promoter CTD PMID:29626692 NCBI chr 3:46,350,237...46,368,397
Ensembl chr 3:46,351,213...46,361,041 		JBrowse link
G Tbx4 T-box transcription factor 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TBX4 promoter CTD PMID:29626692 NCBI chr10:70,730,686...70,760,829
Ensembl chr10:70,731,163...70,760,825 		JBrowse link
G Tcap titin-cap multiple interactions
decreases expression		 ISO SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of TCAP mRNA] CTD PMID:21514415 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
G Tceanc2 transcription elongation factor A N-terminal and central domain containing 2 affects methylation ISO Asbestos, Serpentine affects the methylation of TCEANC2 5' UTR CTD PMID:29523930 NCBI chr 5:121,923,959...121,963,018
Ensembl chr 5:121,923,956...121,962,183 		JBrowse link
G Tert telomerase reverse transcriptase increases response to substance ISO TERT protein results in increased susceptibility to Asbestos, Serpentine CTD PMID:15182483 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tex19.2 testis expressed gene 19.2 increases expression ISO Asbestos, Serpentine results in increased expression of TEX19 mRNA CTD PMID:21148743 NCBI chr10:106,379,757...106,382,344
Ensembl chr10:106,379,757...106,382,344 		JBrowse link
G Tfpi2 tissue factor pathway inhibitor 2 increases expression ISO Asbestos, Serpentine results in increased expression of TFPI2 mRNA CTD PMID:24160326 NCBI chr 4:31,981,786...31,986,707
Ensembl chr 4:31,982,178...31,986,600 		JBrowse link
G Tgfa transforming growth factor alpha multiple interactions
increases expression		 ISO
EXP		 [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of TGFA mRNA]
Asbestos, Serpentine results in increased expression of TGFA mRNA; Asbestos, Serpentine results in increased expression of TGFA protein		 CTD PMID:8686744 PMID:9846974 NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases secretion
increases expression
increases activity
affects expression		 ISO
EXP		 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Asbestos, Serpentine results in increased secretion of TGFB1 protein]; pyrazolanthrone inhibits the reaction [Asbestos, Serpentine results in increased secretion of TGFB1 protein]; SB 203580 inhibits the reaction [Asbestos, Serpentine results in increased secretion of TGFB1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of CDH1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in decreased expression of CTNNB1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of ACTA2 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of FN1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of VIM protein]
Asbestos, Serpentine results in increased expression of TGFB1 protein
Asbestos, Serpentine promotes the reaction [TNF protein results in increased expression of TGFB1 mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TGFB1 protein]; TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of CCN2]
Asbestos, Serpentine results in increased activity of TGFB1 protein
Asbestos, Serpentine results in increased expression of TGFB1; Asbestos, Serpentine results in increased expression of TGFB1 mRNA; Asbestos, Serpentine results in increased expression of TGFB1 protein		 CTD PMID:18039278 PMID:18569384 PMID:19105532 PMID:19817698 PMID:25324550 More... NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO [Asbestos, Serpentine results in decreased susceptibility to Asbestos] which results in decreased expression of TGFBR2 mRNA CTD PMID:25358858 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgif1 TGFB-induced factor homeobox 1 increases methylation ISO Asbestos, Serpentine results in increased methylation of TGIF1 5' UTR CTD PMID:29523930 NCBI chr 9:110,748,094...110,757,714
Ensembl chr 9:110,720,921...110,757,802 		JBrowse link
G Thbd thrombomodulin decreases expression ISO Asbestos, Serpentine results in decreased expression of THBD mRNA CTD PMID:16251409 NCBI chr 3:135,863,366...135,867,018
Ensembl chr 3:135,862,835...135,867,193 		JBrowse link
G Thbs1 thrombospondin 1 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of THBS1 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of THBS1 mRNA]		 CTD PMID:21514415 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 increases expression ISO Asbestos, Serpentine results in increased expression of THBS2 mRNA CTD PMID:29523930 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Thrsp thyroid hormone responsive decreases expression
multiple interactions		 ISO Asbestos, Serpentine results in decreased expression of THRSP mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in decreased expression of THRSP mRNA]		 CTD PMID:21514415 NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075 		JBrowse link
G Tiam2 TIAM Rac1 associated GEF 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TIAM2 promoter CTD PMID:29626692 NCBI chr 1:43,918,179...44,119,499
Ensembl chr 1:43,918,174...44,119,493 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of TIMP1 mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]; U 0126 inhibits the reaction [Asbestos, Serpentine results in increased expression of TIMP1 mRNA]		 CTD PMID:16571779 PMID:21514415 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Timp3 TIMP metallopeptidase inhibitor 3 decreases expression
increases expression		 ISO Asbestos, Serpentine results in decreased expression of TIMP3 mRNA
Asbestos, Serpentine results in increased expression of TIMP3 mRNA		 CTD PMID:24160326 NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839 		JBrowse link
G Tinagl1 tubulointerstitial nephritis antigen-like 1 decreases expression ISO Asbestos, Serpentine results in decreased expression of TINAGL1 mRNA CTD PMID:16251409 NCBI chr 5:142,513,710...142,523,730
Ensembl chr 5:142,513,714...142,523,720 		JBrowse link
G Tinf2 TERF1 interacting nuclear factor 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of TINF2 mRNA CTD PMID:29523930 NCBI chr15:29,170,663...29,178,015
Ensembl chr15:29,170,652...29,176,984 		JBrowse link
G Tjp1 tight junction protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of TJP1 mRNA CTD PMID:21148743 NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlcd4 TLC domain containing 4 increases expression ISO Asbestos, Serpentine results in increased expression of TLCD4 mRNA CTD PMID:21148743 NCBI chr 2:209,284,873...209,360,156
Ensembl chr 2:209,289,732...209,341,353 		JBrowse link
G Tlr3 toll-like receptor 3 increases expression ISO Asbestos, Serpentine results in increased expression of TLR3 mRNA CTD PMID:24160326 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Tlx2 T-cell leukemia homeobox 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TLX2 promoter CTD PMID:29626692 NCBI chr 4:115,573,736...115,576,097
Ensembl chr 4:115,573,799...115,575,642 		JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of TMCC2 mRNA CTD PMID:21148743 NCBI chr13:43,794,029...43,831,716
Ensembl chr13:43,794,029...43,831,716 		JBrowse link
G Tmem106a transmembrane protein 106A decreases expression ISO Asbestos, Serpentine results in decreased expression of TMEM106A mRNA CTD PMID:29523930 NCBI chr10:86,506,908...86,515,915
Ensembl chr10:86,506,936...86,515,892 		JBrowse link
G Tmem132d transmembrane protein 132D decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TMEM132D gene CTD PMID:29523930 NCBI chr12:28,270,039...28,917,324
Ensembl chr12:28,270,712...28,915,374 		JBrowse link
G Tmem158 transmembrane protein 158 increases expression ISO Asbestos, Serpentine results in increased expression of TMEM158 mRNA CTD PMID:29523930 NCBI chr 8:122,913,675...122,914,673
Ensembl chr 8:122,913,675...122,914,673 		JBrowse link
G Tmem59 transmembrane protein 59 affects methylation ISO Asbestos, Serpentine affects the methylation of TMEM59 gene CTD PMID:29523930 NCBI chr 5:121,962,507...121,983,625
Ensembl chr 5:121,962,440...121,983,625 		JBrowse link
G Tmprss11d transmembrane serine protease 11D decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TMPRSS11D gene CTD PMID:29523930 NCBI chr14:21,707,336...21,769,398
Ensembl chr14:21,707,336...21,769,396 		JBrowse link
G Tmprss15 transmembrane serine protease 15 affects expression ISO Asbestos, Serpentine affects the expression of TMPRSS15 mRNA CTD PMID:24160326 NCBI chr11:17,677,741...17,802,255
Ensembl chr11:17,677,741...17,802,255 		JBrowse link
G Tmprss3 transmembrane serine protease 3 increases expression ISO Asbestos, Serpentine results in increased expression of TMPRSS3 mRNA CTD PMID:21148743 NCBI chr20:9,254,102...9,273,808
Ensembl chr20:9,254,109...9,274,363 		JBrowse link
G Tnc tenascin C increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of TNC mRNA
SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of TNC mRNA]		 CTD PMID:21514415 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
increases secretion
multiple interactions
affects expression		 ISO
EXP		 Asbestos, Serpentine results in decreased expression of TNF protein
Asbestos, Serpentine results in increased expression of TNF mRNA; Asbestos, Serpentine results in increased expression of TNF protein
Asbestos, Serpentine results in increased secretion of TNF protein
[Asbestos, Serpentine results in decreased susceptibility to Asbestos, Serpentine] which results in decreased expression of TNF protein; RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein]; TNF protein promotes the reaction [Asbestos, Serpentine affects the localization of CTNNB1 protein]
Asbestos, Serpentine promotes the reaction [KDM6B protein affects the expression of TNF mRNA]; Asbestos, Serpentine promotes the reaction [TNF protein results in increased expression of TGFB1 mRNA]; KDM6B protein affects the reaction [Asbestos, Serpentine results in increased expression of TNF mRNA]; leflunomide affects the reaction [Asbestos, Serpentine affects the expression of TNF mRNA]; polyethylene glycol-superoxide dismutase affects the reaction [STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF mRNA]]; RAC1 protein affects the reaction [Asbestos, Serpentine results in increased expression of TNF mRNA]; RAC1 protein inhibits the reaction [Asbestos, Serpentine results in increased secretion of TNF protein]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF mRNA]; STAT6 protein affects the reaction [Asbestos, Serpentine affects the expression of TNF protein]
[Asbestos, Serpentine co-treated with Lipopolysaccharides] results in increased expression of TNF mRNA; Asbestos, Serpentine affects the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Asbestos, Serpentine affects the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; TNF protein promotes the reaction [Asbestos, Serpentine results in increased expression of CCL2 mRNA]; TNF protein promotes the reaction [Asbestos, Serpentine results in increased secretion of CCL2 protein]
Asbestos, Serpentine affects the expression of TNF mRNA; Asbestos, Serpentine affects the expression of TNF protein		 CTD PMID:7539275 PMID:7849857 PMID:8454952 PMID:8473757 PMID:9400719 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfaip2 TNF alpha induced protein 2 affects expression ISO Asbestos, Serpentine affects the expression of TNFAIP2 mRNA CTD PMID:24160326 NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914 		JBrowse link
G Tnfaip3 TNF alpha induced protein 3 affects expression ISO Asbestos, Serpentine affects the expression of TNFAIP3 mRNA CTD PMID:24160326 NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282 		JBrowse link
G Tnfaip6 TNF alpha induced protein 6 increases expression ISO Asbestos, Serpentine results in increased expression of TNFAIP6 mRNA CTD PMID:24160326 NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649 		JBrowse link
G Tnfaip8 TNF alpha induced protein 8 affects expression
decreases methylation		 ISO Asbestos, Serpentine affects the expression of TNFAIP8 mRNA
Asbestos, Serpentine results in decreased methylation of TNFAIP8 gene		 CTD PMID:24160326 PMID:29523930 NCBI chr18:43,183,854...43,299,512
Ensembl chr18:43,183,916...43,299,517 		JBrowse link
G Tnfaip8l2 TNF alpha induced protein 8 like 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of TNFAIP8L2 5' UTR CTD PMID:29523930 NCBI chr 2:182,710,433...182,726,724
Ensembl chr 2:182,709,378...182,726,760 		JBrowse link
G Tnfrsf19 TNF receptor superfamily member 19 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TNFRSF19 5' UTR CTD PMID:29523930 NCBI chr15:35,092,206...35,158,472
Ensembl chr15:35,092,206...35,180,795 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A multiple interactions ISO [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of PDGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of TGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] results in decreased susceptibility to Asbestos, Serpentine CTD PMID:9846974 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B multiple interactions ISO [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of PDGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] inhibits the reaction [Asbestos, Serpentine results in increased expression of TGFA mRNA]; [TNFRSF1A gene mutant form co-treated with TNFRSF1B gene mutant form] results in decreased susceptibility to Asbestos, Serpentine CTD PMID:9846974 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO Asbestos, Serpentine results in increased expression of TNFRSF9 mRNA CTD PMID:23917077 PMID:24160326 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO Asbestos, Serpentine results in increased expression of TNFSF10 mRNA CTD PMID:24160326 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tnip1 TNFAIP3 interacting protein 1 affects expression ISO Asbestos, Serpentine affects the expression of TNIP1 mRNA CTD PMID:24160326 NCBI chr10:39,037,048...39,084,328
Ensembl chr10:39,037,058...39,077,625 		JBrowse link
G Tnnt2 troponin T2, cardiac type increases expression ISO Asbestos, Serpentine results in increased expression of TNNT2 mRNA CTD PMID:23917077 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388 		JBrowse link
G Tnr tenascin R increases methylation ISO Asbestos, Serpentine results in increased methylation of TNR 5' UTR CTD PMID:29523930 NCBI chr13:71,751,714...72,172,731
Ensembl chr13:72,091,585...72,167,641 		JBrowse link
G Tns2 tensin 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of TNS2 mRNA CTD PMID:16251409 NCBI chr 7:133,229,746...133,247,889
Ensembl chr 7:133,206,364...133,247,888 		JBrowse link
G Tollip toll interacting protein increases expression ISO Asbestos, Serpentine results in increased expression of TOLLIP mRNA CTD PMID:21148743 NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625 		JBrowse link
G Tomm22 translocase of outer mitochondrial membrane 22 decreases expression ISO Asbestos, Serpentine results in decreased expression of TOMM22 mRNA CTD PMID:21148743 NCBI chr 7:111,223,508...111,228,671
Ensembl chr 7:111,216,571...111,246,799 		JBrowse link
G Tox2 TOX high mobility group box family member 2 increases expression ISO Asbestos, Serpentine results in increased expression of TOX2 mRNA CTD PMID:16251409 NCBI chr 3:151,853,294...151,980,086
Ensembl chr 3:151,853,294...151,980,749 		JBrowse link
G Tp53 tumor protein p53 increases phosphorylation
multiple interactions
increases expression
decreases expression		 ISO
EXP		 Asbestos, Serpentine results in increased phosphorylation of TP53 protein
wortmannin inhibits the reaction [Asbestos, Serpentine results in increased expression of TP53 protein]; wortmannin inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of TP53 protein]
Asbestos, Serpentine results in decreased expression of TP53 mRNA; Asbestos, Serpentine results in decreased expression of TP53 protein		 CTD PMID:9115760 PMID:12676607 PMID:32755622 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpbg trophoblast glycoprotein increases expression ISO Asbestos, Serpentine results in increased expression of TPBG mRNA CTD PMID:29523930 NCBI chr 8:86,793,953...86,797,324
Ensembl chr 8:86,793,749...86,797,741 		JBrowse link
G Traf1 TNF receptor-associated factor 1 affects expression ISO Asbestos, Serpentine affects the expression of TRAF1 mRNA CTD PMID:24160326 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Tram1 translocation associated membrane protein 1 increases expression ISO Asbestos, Serpentine results in increased expression of TRAM1 mRNA CTD PMID:16251409 NCBI chr 5:5,642,579...5,667,666
Ensembl chr 5:5,642,546...5,686,971 		JBrowse link
G Trim29 tripartite motif-containing 29 increases methylation ISO Asbestos, Serpentine results in increased methylation of TRIM29 exon CTD PMID:29523930 NCBI chr 8:43,682,221...43,706,992
Ensembl chr 8:43,682,221...43,706,992 		JBrowse link
G Trnau1ap tRNA selenocysteine 1 associated protein 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of TRNAU1AP 5' UTR CTD PMID:29523930 NCBI chr 5:144,507,044...144,524,142
Ensembl chr 5:144,507,615...144,524,131 		JBrowse link
G Trrap transformation/transcription domain-associated protein increases methylation ISO Asbestos, Serpentine results in increased methylation of TRRAP gene CTD PMID:29523930 NCBI chr12:9,738,006...9,827,708
Ensembl chr12:9,738,006...9,827,674 		JBrowse link
G Tshz1 teashirt zinc finger homeobox 1 increases expression ISO Asbestos, Serpentine results in increased expression of TSHZ1 mRNA CTD PMID:21148743 NCBI chr18:77,376,399...77,452,815
Ensembl chr18:77,377,394...77,453,509 		JBrowse link
G Tshz3 teashirt zinc finger homeobox 3 increases methylation ISO Asbestos, Serpentine results in increased methylation of TSHZ3 3' UTR CTD PMID:29523930 NCBI chr 1:89,386,732...89,460,719
Ensembl chr 1:89,381,858...89,460,874 		JBrowse link
G Tslp thymic stromal lymphopoietin increases expression ISO Asbestos, Serpentine results in increased expression of TSLP mRNA CTD PMID:24160326 NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548 		JBrowse link
G Ttn titin increases methylation ISO Asbestos, Serpentine results in increased methylation of TTN 5' UTR CTD PMID:29523930 NCBI chr 3:61,652,432...61,924,912
Ensembl chr 3:61,652,439...61,924,741 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Asbestos, Serpentine results in increased expression of TWIST1 protein CTD PMID:30609805 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Ubp1 upstream binding protein 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of UBP1 promoter CTD PMID:29626692 NCBI chr 8:113,869,771...113,915,625
Ensembl chr 8:113,869,979...113,915,625 		JBrowse link
G Ubtd2 ubiquitin domain containing 2 affects expression ISO Asbestos, Serpentine affects the expression of UBTD2 mRNA CTD PMID:24160326 NCBI chr10:17,037,716...17,100,263
Ensembl chr10:17,038,019...17,104,411 		JBrowse link
G Ugp2 UDP-glucose pyrophosphorylase 2 affects expression ISO Asbestos, Serpentine affects the expression of UGP2 mRNA CTD PMID:24160326 NCBI chr14:95,456,330...95,497,483
Ensembl chr14:95,456,330...95,496,830 		JBrowse link
G Unc45b unc-45 myosin chaperone B decreases methylation ISO Asbestos, Serpentine results in decreased methylation of UNC45B 3' UTR; Asbestos, Serpentine results in decreased methylation of UNC45B 5' UTR CTD PMID:29523930 NCBI chr10:67,845,464...67,873,143
Ensembl chr10:67,845,462...67,873,389 		JBrowse link
G Uqcc2 ubiquinol-cytochrome c reductase complex assembly factor 2 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of UQCC2 5' UTR CTD PMID:29523930 NCBI chr20:5,202,837...5,214,541
Ensembl chr20:5,202,837...5,214,164 		JBrowse link
G Ush2a usherin decreases methylation ISO Asbestos, Serpentine results in decreased methylation of USH2A gene CTD PMID:29523930 NCBI chr13:99,837,445...100,503,935
Ensembl chr13:99,837,445...100,503,922 		JBrowse link
G Usp2 ubiquitin specific peptidase 2 decreases expression ISO Asbestos, Serpentine results in decreased expression of USP2 mRNA CTD PMID:24160326 NCBI chr 8:44,411,457...44,439,668
Ensembl chr 8:44,411,607...44,438,331 		JBrowse link
G Usp36 ubiquitin specific peptidase 36 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of USP36 5' UTR CTD PMID:29523930 NCBI chr10:103,497,349...103,528,877
Ensembl chr10:103,497,349...103,528,877 		JBrowse link
G Vax1 ventral anterior homeobox 1 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of VAX1 promoter CTD PMID:29626692 NCBI chr 1:258,324,571...258,342,396
Ensembl chr 1:258,326,276...258,330,192 		JBrowse link
G Vcam1 vascular cell adhesion molecule 1 decreases expression
increases expression
multiple interactions		 ISO
EXP		 Asbestos, Serpentine results in decreased expression of VCAM1 mRNA
Asbestos, Serpentine results in increased expression of VCAM1 mRNA
Asbestos, Serpentine promotes the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Asbestos, Serpentine promotes the reaction [IL1B protein results in increased expression of VCAM1 protein]		 CTD PMID:10444523 PMID:24160326 NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958 		JBrowse link
G Vcan versican multiple interactions
increases expression		 ISO SPP1 gene mutant form inhibits the reaction [Asbestos, Serpentine results in increased expression of VCAN mRNA] CTD PMID:21514415 NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637 		JBrowse link
G Vezt vezatin, adherens junctions transmembrane protein decreases methylation ISO Asbestos, Serpentine results in decreased methylation of VEZT gene CTD PMID:29523930 NCBI chr 7:28,512,214...28,597,429
Ensembl chr 7:28,534,249...28,597,356 		JBrowse link
G Vgf VGF nerve growth factor inducible increases expression ISO Asbestos, Serpentine results in increased expression of VGF mRNA CTD PMID:29523930 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341 		JBrowse link
G Vim vimentin increases expression
multiple interactions		 ISO Asbestos, Serpentine results in increased expression of VIM mRNA; Asbestos, Serpentine results in increased expression of VIM protein
TGFB1 protein affects the reaction [Asbestos, Serpentine results in increased expression of VIM protein]		 CTD PMID:24160326 PMID:26685284 PMID:30609805 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vps4b vacuolar protein sorting 4 homolog B increases expression ISO Asbestos, Serpentine results in increased expression of VPS4B CTD PMID:19105532 NCBI chr13:22,907,105...22,932,200
Ensembl chr13:22,907,109...22,932,229 		JBrowse link
G Vrk3 VRK serine/threonine kinase 3 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of VRK3 promoter CTD PMID:29626692 NCBI chr 1:95,243,344...95,270,780
Ensembl chr 1:95,243,364...95,270,780 		JBrowse link
G Vsig10 V-set and immunoglobulin domain containing 10 increases expression ISO Asbestos, Serpentine results in increased expression of VSIG10 mRNA CTD PMID:23917077 NCBI chr12:39,241,332...39,277,302
Ensembl chr12:39,241,334...39,275,360 		JBrowse link
G Vti1a vesicle transport through interaction with t-SNAREs 1A increases methylation ISO Asbestos, Serpentine results in increased methylation of VTI1A gene CTD PMID:29523930 NCBI chr 1:254,356,343...254,661,854
Ensembl chr 1:254,356,429...254,661,852 		JBrowse link
G Vwa8 von Willebrand factor A domain containing 8 increases methylation ISO Asbestos, Serpentine results in increased methylation of VWA8 gene CTD PMID:29523930 NCBI chr15:54,252,703...54,576,871
Ensembl chr15:54,252,584...54,576,870 		JBrowse link
G Vwf von Willebrand factor decreases expression ISO Asbestos, Serpentine results in decreased expression of VWF mRNA CTD PMID:21148743 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wdr33 WD repeat domain 33 increases expression ISO Asbestos, Serpentine results in increased expression of WDR33 mRNA CTD PMID:21148743 NCBI chr18:23,432,233...23,535,460
Ensembl chr18:23,432,191...23,468,597 		JBrowse link
G Wnk4 WNK lysine deficient protein kinase 4 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of WNK4 promoter CTD PMID:29626692 NCBI chr10:86,202,552...86,219,655
Ensembl chr10:86,188,812...86,231,829 		JBrowse link
G Wnt10a Wnt family member 10A decreases methylation ISO Asbestos, Serpentine results in decreased methylation of WNT10A promoter CTD PMID:29626692 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Wnt11 Wnt family member 11 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of WNT11 promoter CTD PMID:29626692 NCBI chr 1:153,134,503...153,154,294
Ensembl chr 1:153,138,197...153,154,294 		JBrowse link
G Wnt5b Wnt family member 5B increases expression
decreases methylation		 ISO Asbestos, Serpentine results in increased expression of WNT5B mRNA
Asbestos, Serpentine results in decreased methylation of WNT5B promoter		 CTD PMID:29523930 PMID:29626692 NCBI chr 4:152,609,566...152,733,790
Ensembl chr 4:152,609,569...152,733,407 		JBrowse link
G Wnt7a Wnt family member 7A decreases methylation ISO Asbestos, Serpentine results in decreased methylation of WNT7A promoter CTD PMID:29626692 NCBI chr 4:123,863,108...123,908,981
Ensembl chr 4:123,863,108...123,908,981 		JBrowse link
G Wwox WW domain-containing oxidoreductase increases expression ISO Asbestos, Serpentine results in increased expression of WWOX mRNA CTD PMID:21148743 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
G Xbp1 X-box binding protein 1 increases splicing ISO Asbestos, Serpentine results in increased splicing of XBP1 mRNA CTD PMID:25324550 NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693 		JBrowse link
G Xk X-linked Kx blood group antigen, Kell and VPS13A binding protein decreases expression ISO Asbestos, Serpentine results in decreased expression of XK mRNA CTD PMID:21148743 NCBI chr  X:13,436,412...13,472,830
Ensembl chr  X:13,436,418...13,472,830 		JBrowse link
G Zc3h12d zinc finger CCCH type containing 12D decreases expression ISO Asbestos, Serpentine results in decreased expression of ZC3H12D mRNA CTD PMID:21148743 NCBI chr 1:2,313,110...2,348,820
Ensembl chr 1:2,314,324...2,348,819 		JBrowse link
G Zc3h7a zinc finger CCCH type containing 7 A increases expression ISO Asbestos, Serpentine results in increased expression of ZC3H7A mRNA CTD PMID:21148743 NCBI chr10:4,473,177...4,512,668
Ensembl chr10:4,473,203...4,512,665 		JBrowse link
G Zcchc2 zinc finger CCHC-type containing 2 increases expression ISO Asbestos, Serpentine results in increased expression of ZCCHC2 mRNA CTD PMID:21148743 NCBI chr13:22,118,677...22,193,626
Ensembl chr13:22,119,568...22,166,373 		JBrowse link
G Zeb1 zinc finger E-box binding homeobox 1 increases expression ISO Asbestos, Serpentine results in increased expression of ZEB1 protein CTD PMID:30609805 NCBI chr17:51,948,948...52,116,018
Ensembl chr17:51,948,948...52,115,214 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of ZEB2 gene CTD PMID:29523930 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
G Zfhx3 zinc finger homeobox 3 increases methylation ISO Asbestos, Serpentine results in increased methylation of ZFHX3 5' UTR CTD PMID:29523930 NCBI chr19:36,257,196...36,886,104
Ensembl chr19:36,630,254...36,881,771 		JBrowse link
G Zfp385b zinc finger protein 385B increases methylation ISO Asbestos, Serpentine results in increased methylation of ZNF385B 5' UTR CTD PMID:29523930 NCBI chr 3:62,355,182...62,640,417
Ensembl chr 3:62,355,196...62,640,510 		JBrowse link
G Zfp42 zinc finger protein 42 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ZFP42 5' UTR CTD PMID:29523930 NCBI chr16:48,836,463...48,845,443
Ensembl chr16:48,836,648...48,845,401 		JBrowse link
G Zfp483 zinc finger protein 483 decreases expression ISO Asbestos, Serpentine results in decreased expression of ZNF483 mRNA CTD PMID:29523930 NCBI chr 5:73,763,201...73,780,511
Ensembl chr 5:73,763,179...73,776,223 		JBrowse link
G Znrf2 zinc and ring finger 2 increases methylation ISO Asbestos, Serpentine results in increased methylation of ZNRF2 gene CTD PMID:29523930 NCBI chr 4:83,950,406...84,032,676
Ensembl chr 4:83,949,309...84,027,818 		JBrowse link
G Zswim5 zinc finger, SWIM-type containing 5 decreases methylation ISO Asbestos, Serpentine results in decreased methylation of ZSWIM5 gene CTD PMID:29523930 NCBI chr 5:130,346,733...130,463,791
Ensembl chr 5:130,343,034...130,463,784 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19890
    chemical entity 19867
      chemical substance 14415
        mineral 4326
          silicate mineral 3762
            serpentine mineral 772
              serpentine asbestos 772
                chrysotile 0
paths to the root