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Gene: Cap2 (cyclase associated actin cytoskeleton regulatory protein 2) Rattus norvegicus

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Symbol:

Cap2

Name:

cyclase associated actin cytoskeleton regulatory protein 2

RGD ID:

620310

Description:

Predicted to enable actin binding activity; adenylate cyclase binding activity; and identical protein binding activity. Involved in regulation of modification of postsynaptic actin cytoskeleton. Is active in glutamatergic synapse and postsynapse. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human CAP2 (cyclase associated actin cytoskeleton regulatory protein 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 3,3',4,4',5-pentachlorobiphenyl.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

adenylyl cyclase-associated protein 2; CAP 2; CAP, adenylate cyclase-associated protein, 2; CAP, adenylate cyclase-associated protein, 2 (yeast)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	18,260,462 - 18,409,681 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	18,261,646 - 18,409,563 (-)	Ensembl				GRCr8
mRatBN7.2	17	18,054,234 - 18,203,453 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	18,054,431 - 18,203,373 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	17,941,405 - 18,089,565 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	19,545,274 - 19,693,435 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	17,868,534 - 18,016,688 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	18,441,614 - 18,592,866 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	18,442,127 - 18,592,750 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	19,345,220 - 19,493,214 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	17	17,763,871 - 17,910,638 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

dilated cardiomyopathy (ISS)

Dilated Cardiomyopathy 2I (ISO)

hepatocellular carcinoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene (ISO)

17beta-hydroxy-5alpha-androstan-3-one (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,2',5,5'-tetrachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,4'-trichlorobiphenyl (ISO)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,7-dihydropurine-6-thione (EXP)

5-fluorouracil (ISO)

6-propyl-2-thiouracil (EXP)

acrylamide (EXP,ISO)

actinomycin D (ISO)

afimoxifene (ISO)

alpha-Zearalanol (EXP)

AM-251 (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cantharidin (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chloropicrin (ISO)

cisplatin (ISO)

clofibrate (EXP)

clofibric acid (EXP)

cocaine (EXP)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

corosolic acid (ISO)

coumarin (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

dibutyl phthalate (EXP,ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

furan (EXP)

gentamycin (EXP)

hydrogen peroxide (ISO)

mercaptopurine (EXP)

methotrexate (ISO)

methoxychlor (EXP)

nickel atom (ISO)

nitrofen (EXP)

Nutlin-3 (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

paraquat (EXP)

PCB138 (ISO)

perfluorooctanoic acid (EXP)

phenobarbital (ISO)

progesterone (EXP)

purine-6-thiol (EXP)

rac-lactic acid (ISO)

raloxifene (EXP)

resveratrol (ISO)

SB 431542 (ISO)

selenium atom (ISO)

serpentine asbestos (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

streptozocin (ISO)

sunitinib (ISO)

tamoxifen (ISO)

taurine (ISO)

tetrachloromethane (EXP)

triclosan (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA,TAS)

actin filament organization (IBA)

cell morphogenesis (IBA)

cytoskeleton organization (IEA,TAS)

obsolete cAMP-mediated signaling (IBA)

presynaptic actin cytoskeleton organization (ISO)

regulation of modification of postsynaptic actin cytoskeleton (IDA,IMP)

Cellular Component

cytoplasm (IBA)

glutamatergic synapse (IDA,IEP)

plasma membrane (IEA)

postsynapse (IDA,IEP)

postsynaptic density (ISO)

Molecular Function

actin binding (IBA,IEA)

adenylate cyclase binding (IBA)

identical protein binding (ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	An actin-binding protein, CAP, is expressed in a subset of rat taste bud cells.	Ishimaru Y, etal., Neuroreport 2001 Feb 12,;12(2):233-5.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	Cyclase-associated protein 2 dimerization regulates cofilin in synaptic plasticity and Alzheimer's disease.	Pelucchi S, etal., Brain Commun. 2020 Jun 26;2(2):fcaa086. doi: 10.1093/braincomms/fcaa086. eCollection 2020.
7.	GOA pipeline	RGD automated data pipeline
8.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
10.	Differential expression of CAP and CAP2 in adult rat tissues.	Swiston J, etal., Gene 1995 Nov 20;165(2):273-7.

Additional References at PubMed

PMID:17114649	PMID:22871113	PMID:25416956	PMID:29476059

Genomics

Comparative Map Data

Cap2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	17	18,260,462 - 18,409,681 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	17	18,261,646 - 18,409,563 (-)	Ensembl				GRCr8
mRatBN7.2	17	18,054,234 - 18,203,453 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	17	18,054,431 - 18,203,373 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	17	17,941,405 - 18,089,565 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	17	19,545,274 - 19,693,435 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	17	17,868,534 - 18,016,688 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	17	18,441,614 - 18,592,866 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	18,442,127 - 18,592,750 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	17	19,345,220 - 19,493,214 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
Celera	17	17,763,871 - 17,910,638 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

CAP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	6	17,393,595 - 17,557,780 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	6	17,393,375 - 17,557,792 (+)	Ensembl			hg38	GRCh38
GRCh37	6	17,393,826 - 17,558,011 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	6	17,501,715 - 17,666,002 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	6	17,501,714 - 17,666,000	NCBI
Celera	6	18,632,068 - 18,796,067 (+)	NCBI		Celera
Cytogenetic Map	6	p22.3	NCBI
HuRef	6	17,340,107 - 17,502,548 (+)	NCBI		HuRef
CHM1_1	6	17,396,197 - 17,560,514 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	6	17,265,693 - 17,429,911 (+)	NCBI		T2T-CHM13v2.0

Cap2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	46,655,379 - 46,803,757 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	13	46,655,324 - 46,803,757 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	13	46,501,903 - 46,650,281 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	46,501,848 - 46,650,281 (+)	Ensembl			mm10	GRCm38
MGSCv37	13	46,597,272 - 46,745,650 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	13	46,513,119 - 46,661,250 (+)	NCBI		MGSCv36	mm8
Celera	13	47,582,526 - 47,733,794 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI
cM Map	13	23.83	NCBI

Cap2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955483	8,484,427 - 8,603,234 (-)	Ensembl
ChiLan1.0	NW_004955483	8,484,427 - 8,602,748 (-)	NCBI	ChiLan1.0	ChiLan1.0

CAP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	5	32,059,995 - 32,223,059 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	6	28,045,423 - 28,208,045 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	6	17,248,751 - 17,411,593 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	6	17,608,046 - 17,770,160 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	6	17,608,046 - 17,770,160 (+)	Ensembl			panPan2	panpan1.1

CAP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	35	16,336,716 - 16,476,166 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	35	16,336,753 - 16,474,913 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	35	16,289,467 - 16,426,701 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	35	16,443,075 - 16,582,657 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	35	16,442,937 - 16,582,653 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	35	16,259,869 - 16,397,153 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	35	16,312,854 - 16,450,700 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	35	17,646,682 - 17,784,200 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Cap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404946	8,228,988 - 8,335,156 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936552	3,395,649 - 3,501,940 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936552	3,395,785 - 3,501,949 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	13,211,574 - 13,350,961 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	7	13,211,110 - 13,350,966 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	14,007,002 - 14,053,037 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAP2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	17	54,575,289 - 54,742,565 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	17	54,574,145 - 54,742,757 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666044	17,486,737 - 17,764,077 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Cap2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624756	8,989,203 - 9,174,283 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624756	8,990,151 - 9,174,208 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Cap2
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	14	65,479,979 - 65,626,518 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Cap2
950 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	29
Count of miRNA genes:	27
Interacting mature miRNAs:	29
Transcripts:	ENSRNOT00000065742
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	43999106	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9266755	40968173	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4360057	27233623	Rat
8552966	Pigfal18	Plasma insulin-like growth factor 1 level QTL 18	8.7		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	17	12860942	57860942	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2120843	42054133	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9206505	23859062	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
2302377	Scl61	Serum cholesterol level QTL 61	4.36		blood HDL cholesterol amount (VT:0000184)	serum high density lipoprotein cholesterol level (CMO:0000361)	17	6221998	58177198	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9589151	Insul30	Insulin level QTL 30	8.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	12860942	57860942	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31706603	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4733534	49733534	Rat
9589057	Scfw6	Subcutaneous fat weight QTL 6	8.62	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	17	12860942	57860942	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9206505	23859062	Rat
9590154	Scort9	Serum corticosterone level QTL 9	23.57	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	12860942	57860942	Rat
9590088	Insglur7	Insulin/glucose ratio QTL 7	20.38	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	17	12860942	57860942	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	1	22181410	Rat
1331720	Rf43	Renal function QTL 43	2.881		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	17	15537025	28637951	Rat
2317053	Aia25	Adjuvant induced arthritis QTL 25	2.69		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	17	10604694	55604694	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	1	36045694	Rat
1331765	Hrtrt15	Heart rate QTL 15	4.094		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	17	15537025	60531414	Rat
7411666	Foco31	Food consumption QTL 31	11.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	17	12860942	57860942	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	1	21499218	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4733534	49733534	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	8574342	32199534	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	38037084	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9206505	23859062	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	43999106	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4360057	27233623	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	43999106	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2120843	22087569	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9206505	23859062	Rat
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22877318	Rat

Markers in Region

BF387059

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	18,075,482 - 18,075,640 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	18,463,089 - 18,463,246	NCBI	Rnor6.0
Rnor_5.0	17	19,472,585 - 19,472,742	UniSTS	Rnor5.0
Celera	17	17,784,203 - 17,784,360	UniSTS
RH 3.4 Map	17	219.2	UniSTS
Cytogenetic Map	17	p13	UniSTS

RH141344

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	17	18,340,435 - 18,340,624 (+)	Marker Load Pipeline
mRatBN7.2	17	18,134,222 - 18,134,411 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	18,522,062 - 18,522,250	NCBI	Rnor6.0
Rnor_5.0	17	19,413,555 - 19,413,743	UniSTS	Rnor5.0
Celera	17	17,842,767 - 17,842,955	UniSTS
RH 3.4 Map	17	214.7	UniSTS
Cytogenetic Map	17	p13	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
17	13	80	165	78	77	46	35	46	6	315	155	18	138	89	121	31	20	20

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_053874	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253753	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006253754	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039095302	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CH473977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U31935	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000065742 ⟹ ENSRNOP00000062591

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	18,261,646 - 18,409,563 (-)	Ensembl
mRatBN7.2 Ensembl	17	18,054,431 - 18,203,373 (-)	Ensembl
Rnor_6.0 Ensembl	17	18,442,604 - 18,592,750 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078992 ⟹ ENSRNOP00000074020

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	18,261,646 - 18,409,563 (-)	Ensembl
mRatBN7.2 Ensembl	17	18,054,431 - 18,203,373 (-)	Ensembl
Rnor_6.0 Ensembl	17	18,442,127 - 18,590,536 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107796 ⟹ ENSRNOP00000091334

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	18,261,646 - 18,409,563 (-)	Ensembl
mRatBN7.2 Ensembl	17	18,054,431 - 18,203,373 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000144561 ⟹ ENSRNOP00000104613

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	17	18,261,646 - 18,409,082 (-)	Ensembl

RefSeq Acc Id:

NM_053874 ⟹ NP_446326

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	18,261,646 - 18,409,563 (-)	NCBI
mRatBN7.2	17	18,055,420 - 18,203,345 (-)	NCBI
Rnor_6.0	17	18,442,604 - 18,592,750 (-)	NCBI
Rnor_5.0	17	19,345,220 - 19,493,214 (+)	NCBI
Celera	17	17,763,871 - 17,910,638 (-)	RGD

Sequence:

show sequence

GAGCTGGCTTTGCATCACCGAAGCTGGGACCTGGGCTGTACAGCAGAATGGCAGACATGCTGGG
ACTGATGCAGAGGCTGGAATTCGCCGTCAGCCGGCTCGAGCGGCTGTCCTCAGGGTTACACGAA
CCTCCCGGAGGCTGTGGGGAAGTTAACAGCCTCAGTAGAGGCATAGTAGCACCATCCGTGGAAG
CCTTTGACAAACTGATAAACAGTATGGTGGCCGAGTTCTTAAAGAACAGCCGAGTCCTTGCTGG
CGACGTAGAGACTCACGCGGAAATGGTACATGGTGCTTTCCAGGCGCAGCGTGCTTTTCTTCTC
ATGGTCTCTCAGCACCAACAACCCCAGGAGAATGAAGTTGCTGTCCTTCTGAAACCCATATCGG
AGAAGATTCAAGAAATACAGACATTCCGCGAGAGAAACCGGGGGAGCGACATGTTCAACCACCT
CTCGGCAGTCAGCGAGAGCATCGCCGCCCTGGGGTGGATAGCCGTGTCTCCCAAACCTGGTCCA
TATGTCAAGGAGATGAACGACGCCGCCACCTTTTACACTAACAGGGTCCTGAGGGACTACAAGC
ACAGCGATCTGCGCCACGTGGATTGGGTGAGGTCCTATCTCAAGATCTGGAGCGAACTGCAAGC
CTACATCAAGGAGCACCACACCACAGGCCTCACTTGGAGTAAAACTGGTCCTGTAGCATCCACA
GCATCAGCGTTTTCCATTCTCTCCTCTGGGCCCGGTCTCCCTCCACCACCTCCACCACCACCTC
CTCCTGGACCACCTCCCCCTTTTGAGAATGAGGGCGGAAAGGAGGAGCCCTCCCCGTCTCGCTC
AGCTTTGTTTGCCCAGCTAAATCAGGGAGAAGCCATCACAAAAGGGCTCCGACATGTCACGGAC
GACAAGAAAATATACAAGAATCCCAGCTTGAGGGCCCAAGGACAAATTCGATCTCCAACCAAAA
CCCGCACGCCGAGCCCTACATCTTCAAAATCGAATTCTCCTCAGAAACATGCTCCAGTGTTGGA
GTTGGAAGGGAAGAAATGGAGAGTGGAATACCAAGAGGACAGGAATGACCTTGTCATCTCAGAG
ACTGAGCTAAAACAAGTGGCGTACATTTTCAAATGTGACAAATCCACTCTTCAGATAAAGGGAA
AAGTAAACTCCATCACCGTCGATAACTGCAAGAAGTTTGGCCTGGTGTTCGACCATGTGGTGGG
CATCGTGGAAGTGATCAACTCCAAGGACATTCAGATCCAGGTAATGGGGAGAGTGCCAACAATC
TCCATTAATAAGACAGAAGGATGCCACCTGTACCTCAGTAAAGATGCGCTAGACTGTGAGATCG
TGAGCGCCAAGTCGTCCGAGATGAATGTCCTGGTCCCTCAGGGTGACGATTATAGAGAATTTCC
CATTCCTGAGCAGTTCAAGACGATATGGGACGGATCCAAGCTCATCACCGAACCTGCAGAAATC
ATGGCCTGACCTCCAAGAGATATCCTTCCCCGAGTCCCTCCAGCTGGCAGAAGCAAACAGCTAA
TAGGAGCTAGATTTCACCATAGCCCCGGCGTCCATGTCAGCGTCCTGCAGTTCTGTGCCGTGGA
AAACAGTTTCTTTTCTGGCAGGCTTTTATGGGCGTT

hide sequence

RefSeq Acc Id:

XM_006253753 ⟹ XP_006253815

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	18,260,462 - 18,408,916 (-)	NCBI
mRatBN7.2	17	18,054,234 - 18,203,104 (-)	NCBI
Rnor_6.0	17	18,441,614 - 18,592,059 (-)	NCBI
Rnor_5.0	17	19,345,220 - 19,493,214 (+)	NCBI

Sequence:

show sequence

TGCACGTGAGAATGTTTATTCTCATCAACACCACAAAGAGGCTGTGCATTTTAGCCATGTCGGA
ATCCAGGCGTTCTTTATGATATGCCGAGCCTAGATGAGTTACGGACATCATATTCAAGGGGGAC
AACTGTGAACTTACTGTCAAGTGTAGACGAAGGCTTGAGAACAAAAGGCTTGTGAAAAGAATGG
CAGACATGCTGGGACTGATGCAGAGGCTGGAATTCGCCGTCAGCCGGCTGGAGCGGCTGTCCTC
AGGGTTACACGAACCTCCCGGAGGCTGTGGGGAAGTTAACAGCCTCAGTAGAGGCATAGTAGCA
CCATCCGTGGAAGCCTTTGACAAACTGATAAACAGTATGGTGGCCGAGTTCTTAAAAAACAGCC
GAGTCCTTGCTGGCGACGTAGAGACTCACGCGGAAATGGTACATGGTGCTTTCCAGGCGCAGCG
TGCTTTTCTTCTCATGGTCTCTCAGCACCAACAACCCCAGGAGAATGAAGTTGCTGTCCTTCTG
AAACCCATATCGGAGAAGATTCAAGAAATACAGACATTCCGCGAGAGAAACCGGGGGAGCGACA
TGTTCAACCACCTCTCGGCAGTCAGCGAGAGCATCGCCGCCCTGGGGTGGATAGCCGTGTCTCC
CAAACCTGGTCCATATGTCAAGGAGATGAACGACGCCGCCACCTTTTACACTAACAGGGTCCTG
AGGGACTACAAGCACAGCGATCTGCGCCACGTGGATTGGGTGAGGTCCTATCTCAAGATCTGGA
GCGAACTGCAAGCCTACATCAAGGAGCACCACACCACAGGCCTCACTTGGAGTAAAACTGGTCC
TGTAGCATCCACAGCATCAGCGTTTTCCATTCTCTCCTCTGGGCCCGGTCTCCCTCCACCACCT
CCACCACCACCTCCTCCTGGACCACCTCCCCCTTTTGAGAATGAGGGCGGAAAGGAGGAGCCCT
CCCCGTCTCGCTCAGCTTTGTTTGCCCAGCTAAATCAGGGAGAAGCCATCACAAAAGGGCTCCG
ACATGTCACGGACGACAAGAAAATATACAAGAATCCCAGCTTGAGGGCCCAAGGACAAATTCGA
TCTCCAACCAAAACCCGCACGCCGAGCCCTACATCTTCAAAATCGAATTCTCCTCAGAAACATG
CTCCAGTGTTGGAGTTGGAAGGGAAGAAATGGAGAGTGGAATACCAAGAGGACAGGAATGACCT
TGTCATCTCAGAGACTGAGCTAAAACAAGTGGCGTACATTTTCAAATGTGACAAATCCACTCTT
CAGATAAAGGGAAAAGTAAACTCCATCACCGTCGATAACTGCAAGAAGTTTGGCCTGGTGTTCG
ACCATGTGGTGGGCATCGTGGAAGTGATCAACTCCAAGGACATTCAGATCCAGGTAATGGGGAG
AGTGCCAACAATCTCCATTAATAAGACAGAAGGATGCCACCTGTACCTCAGTAAAGATGCGCTA
GACTGTGAGATCGTGAGCGCCAAGTCGTCCGAGATGAATGTCCTGGTCCCTCAGGGTGACGATT
ATAGAGAATTTCCCATTCCTGAGCAGTTCAAGACGATATGGGACGGATCCAAGCTCATCACCGA
ACCTGCAGAAATCATGGCCTGACCTCCAAGAGATATCCTTCCCCGAGTCCCTCCAGCTGGCAGA
AGCAAACAGCTAATAGGAGCTAGATTTCACCATAGCCCCGGCGTCCATGTCAGCGTCCTGCAGT
TCTGTGCCGTGGAAAACAGTTTCTTTTCTGGCAGGCTTTTATGGGCGTTTTGAAATATTTACCA
TTTGATCGTGCTTTGTGTGTGATTTTTACTTCCACATGATAACTAGTGAACACAGCAGAGAGAG
AGAGAAAAGGATTCTGTTCCCATCGGATCACACACCGTGACACCCATTTTGTCCTTTTGGTTTA
ATTGCTAGTTGGAAAAAAAAAATGAAGCCTTAGAGAGTCTATGTCTGTTTTTACCTTTCAGACA
ACTTTAGCATGATGAAATAGTCTTGTGCCCTGAAGAATAAGACTATTTTTTAATTTTCACGTGT
TCACCTTCATCACCGAGGACATCCTGTCAGTGTGAATGTACACTTCAATCCATGTTTTTACACA
CACGTCTACACAAAGAGGAAACAGAATTCTAAGTTTATAGTTACTGAAAAATGAAGGAAATCTT
AACTCCTCATCTTAAACATCCTTCCGCTGAGTCACTTTGAAAATTCTTACTTGTCTGCCTTTCC
CTAAGACAAAGGGTGGTGGCAGAGAGGGGTAGGGTAGGGTGGAGACTCAGTCCTCATTTTTTGC
TCTGTAACACCTTATGGTTCTGTTCCAAGAATAGCTCGACTGTTGGACAACCCCATGCAGGTCT
CTAATGCTTATCAGACATGAGTCCCTCTTCCAATGGCCAGGCTCCCCAGTGCTAACCAGCCTCA
AAGGCAAAAGCCCGAGAGCCACAGCCAGACTGTTGCTTCTCGAATCAGTTGCTTGGCTCTGGTT
GGGTTTCCTAGCCTTGACAGCACACTCTCTCCCAGGTGAGCAACAATGCTCTCCATGTCTCTTC
TCTGCACACGGCCGAGAACTCTGAAGCTTTGGGGCCGTGTGGAGCGAAGCCTAGCGCTGAGCTT
TCGGAACCGATGGGAGCATCTAGACTGTGCCTATGAATGCCTTGCTGGAAGTCATTGTCAGTCT
CTGAATAGCTTCTGTATCCATTTAGTATTTGCATCTCTGATAATTGTGTATCAAAGTTTTGCTA
TAAAAGTTCTGTCCT

hide sequence

RefSeq Acc Id:

XM_006253754 ⟹ XP_006253816

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	18,260,462 - 18,409,681 (-)	NCBI
mRatBN7.2	17	18,054,234 - 18,203,453 (-)	NCBI
Rnor_6.0	17	18,441,614 - 18,592,866 (-)	NCBI
Rnor_5.0	17	19,345,220 - 19,493,214 (+)	NCBI

Sequence:

show sequence

GAGCTGCCGGAAGCCGCGGGCGACTCTCCCCGCGAGCAGCGTGACCGACTCGGGCTCCCGTGCA
GGGGGGAGGCGGAGGCAGCACAGGGCCTGCGGGAGGAGGGCGCGAGTGGCCGGAGCTGGCTTTG
CATCACCGAAGCTGGGACCTGGGCTGTACAGCAGGATATGCCGAGCCTAGATGAGTTACGGACA
TCATATTCAAGGGGGACAACTGTGAACTTACTGTCAAGTGTAGACGAAGGCTTGAGAACAAAAG
GCTTGTGAAAAGAATGGCAGACATGCTGGGACTGATGCAGAGGCTGGAATTCGCCGTCAGCCGG
CTGGAGCGGCTGTCCTCAGGGTTACACGAACCTCCCGGAGGCTGTGGGGAAGTTAACAGCCTCA
GTAGAGGCATAGTAGCACCATCCGTGGAAGCCTTTGACAAACTGATAAACAGTATGGTGGCCGA
GTTCTTAAAAAACAGCCGAGTCCTTGCTGGCGACGTAGAGACTCACGCGGAAATGGTACATGGT
GCTTTCCAGGCGCAGCGTGCTTTTCTTCTCATGGTCTCTCAGCACCAACAACCCCAGGAGAATG
AAGTTGCTGTCCTTCTGAAACCCATATCGGAGAAGATTCAAGAAATACAGACATTCCGCGAGAG
AAACCGGGGGAGCGACATGTTCAACCACCTCTCGGCAGTCAGCGAGAGCATCGCCGCCCTGGGG
TGGATAGCCGTGTCTCCCAAACCTGGTCCATATGTCAAGGAGATGAACGACGCCGCCACCTTTT
ACACTAACAGGGTCCTGAGGGACTACAAGCACAGCGATCTGCGCCACGTGGATTGGGTGAGGTC
CTATCTCAAGATCTGGAGCGAACTGCAAGCCTACATCAAGGAGCACCACACCACAGGCCTCACT
TGGAGTAAAACTGGTCCTGTAGCATCCACAGCATCAGCGTTTTCCATTCTCTCCTCTGGGCCCG
GTCTCCCTCCACCACCTCCACCACCACCTCCTCCTGGACCACCTCCCCCTTTTGAGAATGAGGG
CGGAAAGGAGGAGCCCTCCCCGTCTCGCTCAGCTTTGTTTGCCCAGCTAAATCAGGGAGAAGCC
ATCACAAAAGGGCTCCGACATGTCACGGACGACAAGAAAATATACAAGAATCCCAGCTTGAGGG
CCCAAGGACAAATTCGATCTCCAACCAAAACCCGCACGCCGAGCCCTACATCTTCAAAATCGAA
TTCTCCTCAGAAACATGCTCCAGTGTTGGAGTTGGAAGGGAAGAAATGGAGAGTGGAATACCAA
GAGGACAGGAATGACCTTGTCATCTCAGAGACTGAGCTAAAACAAGTGGCGTACATTTTCAAAT
GTGACAAATCCACTCTTCAGATAAAGGGAAAAGTAAACTCCATCACCGTCGATAACTGCAAGAA
GTTTGGCCTGGTGTTCGACCATGTGGTGGGCATCGTGGAAGTGATCAACTCCAAGGACATTCAG
ATCCAGGTAATGGGGAGAGTGCCAACAATCTCCATTAATAAGACAGAAGGATGCCACCTGTACC
TCAGTAAAGATGCGCTAGACTGTGAGATCGTGAGCGCCAAGTCGTCCGAGATGAATGTCCTGGT
CCCTCAGGGTGACGATTATAGAGAATTTCCCATTCCTGAGCAGTTCAAGACGATATGGGACGGA
TCCAAGCTCATCACCGAACCTGCAGAAATCATGGCCTGACCTCCAAGAGATATCCTTCCCCGAG
TCCCTCCAGCTGGCAGAAGCAAACAGCTAATAGGAGCTAGATTTCACCATAGCCCCGGCGTCCA
TGTCAGCGTCCTGCAGTTCTGTGCCGTGGAAAACAGTTTCTTTTCTGGCAGGCTTTTATGGGCG
TTTTGAAATATTTACCATTTGATCGTGCTTTGTGTGTGATTTTTACTTCCACATGATAACTAGT
GAACACAGCAGAGAGAGAGAGAAAAGGATTCTGTTCCCATCGGATCACACACCGTGACACCCAT
TTTGTCCTTTTGGTTTAATTGCTAGTTGGAAAAAAAAAATGAAGCCTTAGAGAGTCTATGTCTG
TTTTTACCTTTCAGACAACTTTAGCATGATGAAATAGTCTTGTGCCCTGAAGAATAAGACTATT
TTTTAATTTTCACGTGTTCACCTTCATCACCGAGGACATCCTGTCAGTGTGAATGTACACTTCA
ATCCATGTTTTTACACACACGTCTACACAAAGAGGAAACAGAATTCTAAGTTTATAGTTACTGA
AAAATGAAGGAAATCTTAACTCCTCATCTTAAACATCCTTCCGCTGAGTCACTTTGAAAATTCT
TACTTGTCTGCCTTTCCCTAAGACAAAGGGTGGTGGCAGAGAGGGGTAGGGTAGGGTGGAGACT
CAGTCCTCATTTTTTGCTCTGTAACACCTTATGGTTCTGTTCCAAGAATAGCTCGACTGTTGGA
CAACCCCATGCAGGTCTCTAATGCTTATCAGACATGAGTCCCTCTTCCAATGGCCAGGCTCCCC
AGTGCTAACCAGCCTCAAAGGCAAAAGCCCGAGAGCCACAGCCAGACTGTTGCTTCTCGAATCA
GTTGCTTGGCTCTGGTTGGGTTTCCTAGCCTTGACAGCACACTCTCTCCCAGGTGAGCAACAAT
GCTCTCCATGTCTCTTCTCTGCACACGGCCGAGAACTCTGAAGCTTTGGGGCCGTGTGGAGCGA
AGCCTAGCGCTGAGCTTTCGGAACCGATGGGAGCATCTAGACTGTGCCTATGAATGCCTTGCTG
GAAGTCATTGTCAGTCTCTGAATAGCTTCTGTATCCATTTAGTATTTGCATCTCTGATAATTGT
GTATCAAAGTTTTGCTATAAAAGTTCTGTCCT

hide sequence

RefSeq Acc Id:

XM_039095302 ⟹ XP_038951230

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	17	18,260,462 - 18,408,850 (-)	NCBI
mRatBN7.2	17	18,054,234 - 18,202,342 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_446326	(Get FASTA)	NCBI Sequence Viewer
	XP_006253815	(Get FASTA)	NCBI Sequence Viewer
	XP_006253816	(Get FASTA)	NCBI Sequence Viewer
	XP_038951230	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA92298	(Get FASTA)	NCBI Sequence Viewer
	EDL98163	(Get FASTA)	NCBI Sequence Viewer
	EDL98164	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000062591
	ENSRNOP00000062591.2
GenBank Protein	P52481	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_446326 ⟸ NM_053874

- UniProtKB:

P52481 (UniProtKB/Swiss-Prot), A6J714 (UniProtKB/TrEMBL), A0A8L2R883 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKN
SRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGS
DMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKI
WSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEE
PSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQK
HAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLV
FDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGD
DYREFPIPEQFKTIWDGSKLITEPAEIMA

hide sequence

RefSeq Acc Id:	XP_006253816 ⟸ XM_006253754
- Peptide Label:	isoform X1
- UniProtKB:	P52481 (UniProtKB/Swiss-Prot), A6J714 (UniProtKB/TrEMBL), A0A8L2R883 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKN SRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGS DMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKI WSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEE PSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQK HAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLV FDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGD DYREFPIPEQFKTIWDGSKLITEPAEIMA hide sequence

RefSeq Acc Id:	XP_006253815 ⟸ XM_006253753
- Peptide Label:	isoform X1
- UniProtKB:	P52481 (UniProtKB/Swiss-Prot), A6J714 (UniProtKB/TrEMBL), A0A8L2R883 (UniProtKB/TrEMBL)
- Sequence:	show sequence MADMLGLMQRLEFAVSRLERLSSGLHEPPGGCGEVNSLSRGIVAPSVEAFDKLINSMVAEFLKN SRVLAGDVETHAEMVHGAFQAQRAFLLMVSQHQQPQENEVAVLLKPISEKIQEIQTFRERNRGS DMFNHLSAVSESIAALGWIAVSPKPGPYVKEMNDAATFYTNRVLRDYKHSDLRHVDWVRSYLKI WSELQAYIKEHHTTGLTWSKTGPVASTASAFSILSSGPGLPPPPPPPPPPGPPPPFENEGGKEE PSPSRSALFAQLNQGEAITKGLRHVTDDKKIYKNPSLRAQGQIRSPTKTRTPSPTSSKSNSPQK HAPVLELEGKKWRVEYQEDRNDLVISETELKQVAYIFKCDKSTLQIKGKVNSITVDNCKKFGLV FDHVVGIVEVINSKDIQIQVMGRVPTISINKTEGCHLYLSKDALDCEIVSAKSSEMNVLVPQGD DYREFPIPEQFKTIWDGSKLITEPAEIMA hide sequence

Ensembl Acc Id:

ENSRNOP00000062591 ⟸ ENSRNOT00000065742

Ensembl Acc Id:

ENSRNOP00000074020 ⟸ ENSRNOT00000078992

RefSeq Acc Id:	XP_038951230 ⟸ XM_039095302
- Peptide Label:	isoform X1
- UniProtKB:	P52481 (UniProtKB/Swiss-Prot), A6J714 (UniProtKB/TrEMBL), A0A8L2R883 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000091334 ⟸ ENSRNOT00000107796

Ensembl Acc Id:

ENSRNOP00000104613 ⟸ ENSRNOT00000144561

Protein Domains

C-CAP/cofactor C-like

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P52481-F1-model_v2	AlphaFold	P52481	1-477	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700369

Promoter ID:

EPDNEW_R10893

Type:

single initiation site

Name:

Cap2_1

Description:

cyclase associated actin cytoskeleton regulatory protein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	18,592,792 - 18,592,852	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620310	AgrOrtholog
BioCyc Gene	G2FUF-9891	BioCyc
Ensembl Genes	ENSRNOG00000043350	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000065742	ENTREZGENE
	ENSRNOT00000065742.3	UniProtKB/Swiss-Prot
Gene3D-CATH	1.25.40.330	UniProtKB/Swiss-Prot
	2.160.20.70	UniProtKB/Swiss-Prot
InterPro	Adenylate_cyclase-assoc_CAP	UniProtKB/Swiss-Prot
	Adenylate_cyclase-assoc_CAP_C	UniProtKB/Swiss-Prot
	C-CAP_CF_C-like	UniProtKB/Swiss-Prot
	CAP/MinC_C	UniProtKB/Swiss-Prot
	CAP_C_sf	UniProtKB/Swiss-Prot
	CAP_CS_C	UniProtKB/Swiss-Prot
	CAP_CS_N	UniProtKB/Swiss-Prot
	CAP_N	UniProtKB/Swiss-Prot
	CAP_N_sf	UniProtKB/Swiss-Prot
	CARP_motif	UniProtKB/Swiss-Prot
KEGG Report	rno:116653	UniProtKB/Swiss-Prot
NCBI Gene	116653	ENTREZGENE
PANTHER	PTHR10652	UniProtKB/Swiss-Prot
	PTHR10652:SF2	UniProtKB/Swiss-Prot
Pfam	CAP_C	UniProtKB/Swiss-Prot
	CAP_N	UniProtKB/Swiss-Prot
PhenoGen	Cap2	PhenoGen
PROSITE	C_CAP_COFACTOR_C	UniProtKB/Swiss-Prot
	CAP_1	UniProtKB/Swiss-Prot
	CAP_2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000043350	RatGTEx
SMART	CARP	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF101278	UniProtKB/Swiss-Prot
	SSF69340	UniProtKB/Swiss-Prot
UniProt	A0A8I6AQS4_RAT	UniProtKB/TrEMBL
	A0A8L2R883	ENTREZGENE, UniProtKB/TrEMBL
	A0ABK0L4P8_RAT	UniProtKB/TrEMBL
	A6J714	ENTREZGENE, UniProtKB/TrEMBL
	CAP2_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-05-24	Cap2	cyclase associated actin cytoskeleton regulatory protein 2	Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Cap2	CAP, adenylate cyclase-associated protein, 2 (yeast)		adenylyl cyclase-associated protein 2	Name updated	1299863	APPROVED
2002-08-07	Cap2	adenylyl cyclase-associated protein 2			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	enriched in testes; moderately expressed in brain, heart, and skeletal muscle	724618

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM