Arhgap21 (Rho GTPase activating protein 21) - Rat Genome Database

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Gene: Arhgap21 (Rho GTPase activating protein 21) Rattus norvegicus
Analyze
Symbol: Arhgap21
Name: Rho GTPase activating protein 21
RGD ID: 1311028
Description: Predicted to enable GTPase activator activity. Predicted to be involved in several processes, including establishment of Golgi localization; maintenance of Golgi location; and organelle transport along microtubule. Predicted to act upstream of or within regulation of endocytosis. Predicted to be located in several cellular components, including Golgi apparatus; actin cytoskeleton; and cell junction. Orthologous to human ARHGAP21 (Rho GTPase activating protein 21); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC307178; rho GTPase-activating protein 21
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21783,348,673 - 83,472,202 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1783,348,673 - 83,472,444 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01787,725,978 - 87,797,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1787,725,867 - 87,826,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01789,415,087 - 89,486,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41794,817,558 - 94,941,088 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11794,828,397 - 94,951,968 (-)NCBI
Celera1782,609,823 - 82,732,937 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:18662671   PMID:20525016   PMID:24792215  


Genomics

Comparative Map Data
Arhgap21
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21783,348,673 - 83,472,202 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1783,348,673 - 83,472,444 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01787,725,978 - 87,797,436 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1787,725,867 - 87,826,421 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01789,415,087 - 89,486,545 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41794,817,558 - 94,941,088 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11794,828,397 - 94,951,968 (-)NCBI
Celera1782,609,823 - 82,732,937 (-)NCBICelera
Cytogenetic Map17q12.3NCBI
ARHGAP21
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381024,583,614 - 24,723,887 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1024,583,609 - 24,723,887 (-)EnsemblGRCh38hg38GRCh38
GRCh371024,872,543 - 25,012,816 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361024,912,549 - 25,052,550 (-)NCBINCBI36Build 36hg18NCBI36
Build 341024,912,550 - 25,052,550NCBI
Celera1024,564,446 - 24,712,895 (-)NCBICelera
Cytogenetic Map10p12.1NCBI
HuRef1024,534,090 - 24,673,492 (-)NCBIHuRef
CHM1_11024,872,464 - 25,013,653 (-)NCBICHM1_1
T2T-CHM13v2.01024,602,382 - 24,742,515 (-)NCBIT2T-CHM13v2.0
Arhgap21
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39220,852,730 - 20,973,761 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl220,852,730 - 20,973,692 (-)EnsemblGRCm39 Ensembl
GRCm38220,847,919 - 20,968,691 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl220,847,919 - 20,968,881 (-)EnsemblGRCm38mm10GRCm38
MGSCv37220,769,546 - 20,889,348 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36220,765,673 - 20,886,635 (-)NCBIMGSCv36mm8
Celera220,722,855 - 20,850,910 (-)NCBICelera
Cytogenetic Map2A3NCBI
Arhgap21
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554294,424,425 - 4,559,596 (+)NCBIChiLan1.0ChiLan1.0
ARHGAP21
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11025,131,262 - 25,267,188 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1025,132,054 - 25,266,378 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01024,761,427 - 24,898,572 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
ARHGAP21
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.128,740,760 - 8,877,399 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl28,740,119 - 8,877,016 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha27,492,699 - 7,570,795 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.026,941,316 - 7,076,212 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl26,941,307 - 7,075,970 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.126,367,333 - 6,445,123 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.026,386,800 - 6,529,731 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.026,612,602 - 6,694,835 (+)NCBIUU_Cfam_GSD_1.0
Arhgap21
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934424,183,514 - 24,257,210 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936484348,671 - 393,993 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGAP21
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1050,638,719 - 50,669,497 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11050,541,582 - 50,680,156 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21055,994,406 - 56,132,994 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGAP21
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1924,325,648 - 24,459,006 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl924,326,454 - 24,406,743 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605130,261,895 - 30,397,345 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgap21
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247964,201,438 - 4,321,507 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247964,201,335 - 4,321,307 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
D17Got104  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21783,401,813 - 83,402,021 (+)MAPPERmRatBN7.2
mRatBN7.21783,401,813 - 83,402,199 (+)MAPPERmRatBN7.2
Rnor_6.01787,778,558 - 87,779,021NCBIRnor6.0
Rnor_6.01787,778,558 - 87,778,765NCBIRnor6.0
Rnor_5.01789,467,667 - 89,467,874UniSTSRnor5.0
Rnor_5.01789,467,667 - 89,468,130UniSTSRnor5.0
RGSC_v3.41794,870,697 - 94,870,904UniSTSRGSC3.4
RGSC_v3.41794,870,696 - 94,870,904RGDRGSC3.4
RGSC_v3.11794,881,530 - 94,881,737RGD
Celera1782,662,922 - 82,663,129UniSTS
RH 3.4 Map17872.1UniSTS
RH 3.4 Map17872.1RGD
RH 2.0 Map17725.2RGD
Cytogenetic Map17q12.3UniSTS
RH144578  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21783,466,473 - 83,466,687 (+)MAPPERmRatBN7.2
Rnor_6.01787,843,978 - 87,844,191NCBIRnor6.0
Rnor_5.01789,533,087 - 89,533,300UniSTSRnor5.0
RGSC_v3.41794,935,360 - 94,935,573UniSTSRGSC3.4
Celera1782,727,257 - 82,727,470UniSTS
Cytogenetic Map17q12.3UniSTS
RH134054  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2173,396,949 - 73,397,159 (+)MAPPERmRatBN7.2
mRatBN7.21783,348,778 - 83,348,988 (-)MAPPERmRatBN7.2
mRatBN7.2173,396,949 - 73,397,159 (-)MAPPERmRatBN7.2
mRatBN7.21783,348,778 - 83,348,988 (+)MAPPERmRatBN7.2
Rnor_6.01787,726,084 - 87,726,293NCBIRnor6.0
Rnor_6.0165,806,400 - 65,806,609NCBIRnor6.0
Rnor_5.0166,617,538 - 66,617,747UniSTSRnor5.0
Rnor_5.01789,415,193 - 89,415,402UniSTSRnor5.0
RGSC_v3.4172,686,261 - 72,686,470UniSTSRGSC3.4
RGSC_v3.41794,817,664 - 94,817,873UniSTSRGSC3.4
Celera1782,609,929 - 82,610,138UniSTS
Celera160,434,515 - 60,434,724UniSTS
RH 3.4 Map17833.7UniSTS
Cytogenetic Map17q12.3UniSTS
Cytogenetic Map1q21UniSTS
RH142975  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21783,458,908 - 83,459,178 (+)MAPPERmRatBN7.2
Rnor_6.01787,836,412 - 87,836,681NCBIRnor6.0
Rnor_5.01789,525,521 - 89,525,790UniSTSRnor5.0
RGSC_v3.41794,927,794 - 94,928,063UniSTSRGSC3.4
Celera1782,719,691 - 82,719,960UniSTS
RH 3.4 Map17874.61UniSTS
Cytogenetic Map17q12.3UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358295Aocep1Aortic cell protein QTL 16.10.00000071thoracic aorta cellular protein amount (VT:0010598)aortic cell percentage174099000585990005Rat
7411575Bw140Body weight QTL 14030.20.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
8694181Bw151Body weight QTL 1514.360.001body mass (VT:0001259)body weight gain (CMO:0000420)174856093586533673Rat
2317038Ginf3Gastrointestinal inflammation QTL 32.890.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)174992015486533673Rat
2303580Gluco49Glucose level QTL 492blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)175004027186533673Rat
4889894Eae33Experimental allergic encephalomyelitis QTL 335.20.0001nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)175090909986022412Rat
2317045Aia11Adjuvant induced arthritis QTL 114.06joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)176078142686533673Rat
7411577Bw141Body weight QTL 1410.001body mass (VT:0001259)body weight gain (CMO:0000420)176261951686533673Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:496
Count of miRNA genes:265
Interacting mature miRNAs:308
Transcripts:ENSRNOT00000068156
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 43 35 25 10 25 1 1 74 35 35 11 1
Low 1 22 16 9 16 7 10 6 7
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001191693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JACYVU010000294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000068156   ⟹   ENSRNOP00000060787
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1783,348,673 - 83,448,927 (-)Ensembl
Rnor_6.0 Ensembl1787,725,867 - 87,826,421 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096893   ⟹   ENSRNOP00000078699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1783,348,819 - 83,472,444 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000110900   ⟹   ENSRNOP00000085743
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1783,348,819 - 83,472,444 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118116   ⟹   ENSRNOP00000097241
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1783,349,454 - 83,448,927 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118737   ⟹   ENSRNOP00000093003
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1783,348,819 - 83,472,444 (-)Ensembl
RefSeq Acc Id: NM_001191693   ⟹   NP_001178622
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21783,348,673 - 83,472,202 (-)NCBI
Rnor_6.01787,725,978 - 87,797,436 (-)NCBI
Rnor_5.01789,415,087 - 89,486,545 (-)NCBI
Celera1782,609,823 - 82,732,937 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001178622 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001178622   ⟸   NM_001191693
- Sequence:
RefSeq Acc Id: ENSRNOP00000060787   ⟸   ENSRNOT00000068156
RefSeq Acc Id: ENSRNOP00000093003   ⟸   ENSRNOT00000118737
RefSeq Acc Id: ENSRNOP00000085743   ⟸   ENSRNOT00000110900
RefSeq Acc Id: ENSRNOP00000078699   ⟸   ENSRNOT00000096893
RefSeq Acc Id: ENSRNOP00000097241   ⟸   ENSRNOT00000118116
Protein Domains
PDZ   PH   Rho-GAP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1LXQ7-F1-model_v2 AlphaFold F1LXQ7 1-1955 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311028 AgrOrtholog
BioCyc Gene G2FUF-8512 BioCyc
Ensembl Genes ENSRNOG00000008659 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000060787.3 UniProtKB/TrEMBL
  ENSRNOP00000078699 ENTREZGENE
  ENSRNOP00000078699.1 UniProtKB/TrEMBL
  ENSRNOP00000085743.1 UniProtKB/TrEMBL
  ENSRNOP00000093003.1 UniProtKB/TrEMBL
  ENSRNOP00000097241.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000068156.4 UniProtKB/TrEMBL
  ENSRNOT00000096893 ENTREZGENE
  ENSRNOT00000096893.1 UniProtKB/TrEMBL
  ENSRNOT00000110900.1 UniProtKB/TrEMBL
  ENSRNOT00000118116.1 UniProtKB/TrEMBL
  ENSRNOT00000118737.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.555.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  2.30.42.10 UniProtKB/TrEMBL
InterPro PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_6 UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Rho_GTPase_activation_prot UniProtKB/TrEMBL
  RhoGAP_dom UniProtKB/TrEMBL
NCBI Gene 307178 ENTREZGENE
Pfam PDZ_6 UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
PhenoGen Arhgap21 PhenoGen
PROSITE PDZ UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  RHOGAP UniProtKB/TrEMBL
SMART PDZ UniProtKB/TrEMBL
  RhoGAP UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  Rho_GAP UniProtKB/TrEMBL
UniProt A0A8I5ZNY8_RAT UniProtKB/TrEMBL
  A0A8I6AIU0_RAT UniProtKB/TrEMBL
  A0A8I6B5H9_RAT UniProtKB/TrEMBL
  A0A8I6GDA1_RAT UniProtKB/TrEMBL
  F1LXQ7_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Arhgap21  Rho GTPase activating protein 21   Arhgap21_predicted  Rho GTPase activating protein 21 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Arhgap21_predicted  Rho GTPase activating protein 21 (predicted)      Symbol and Name status set to approved 70820 APPROVED