Dtnbp1 (dystrobrevin binding protein 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Dtnbp1 (dystrobrevin binding protein 1) Rattus norvegicus
Analyze
Symbol: Dtnbp1
Name: dystrobrevin binding protein 1
RGD ID: 1590759
Description: Involved in several processes, including negative regulation of dendritic spine morphogenesis; positive regulation of transport; and regulation of dopamine receptor signaling pathway. Located in several cellular components, including dendritic spine; neuronal cell body; and synaptic vesicle membrane. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome 7 and schizophrenia. Orthologous to human DTNBP1 (dystrobrevin binding protein 1); INTERACTS WITH 1,3-dinitrobenzene; bisphenol A; Cuprizon.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: biogenesis of lysosome-related organelles complex 1 subunit 8; BLOC-1 subunit 8; distrobrevin binding protein 1; dysbindin; dysbindin-1; dystrobrevin-binding protein 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21719,685,218 - 19,776,668 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,685,215 - 19,776,661 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1719,569,853 - 19,660,683 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01721,173,678 - 21,264,514 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01719,496,978 - 19,587,817 (+)NCBIRnor_WKY
Rnor_6.01720,090,136 - 20,182,332 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1720,090,246 - 20,182,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01722,105,208 - 22,193,087 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1719,386,624 - 19,477,026 (+)NCBICelera
Cytogenetic Map17p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function
protein binding  (IPI,ISO)

References

References - curated
# Reference Title Reference Citation
1. Nucleocytoplasmic shuttling of dysbindin-1, a schizophrenia-related protein, regulates synapsin I expression. Fei E, etal., J Biol Chem. 2010 Dec 3;285(49):38630-40. doi: 10.1074/jbc.M110.107912. Epub 2010 Oct 4.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Evidence that the BLOC-1 protein dysbindin modulates dopamine D2 receptor internalization and signaling but not D1 internalization. Iizuka Y, etal., J Neurosci. 2007 Nov 7;27(45):12390-5.
4. Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation. Ito H, etal., Mol Psychiatry. 2010 Oct;15(10):976-86. doi: 10.1038/mp.2010.69. Epub 2010 Jun 8.
5. Hermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1). Li W, etal., Nat Genet. 2003 Sep;35(1):84-9. Epub 2003 Aug 17.
6. Developmental expression of dysbindin in Muller cells of rat retina. Matteucci A, etal., Exp Eye Res. 2013 Nov;116:1-8. doi: 10.1016/j.exer.2013.08.006. Epub 2013 Aug 14.
7. Evidence of novel neuronal functions of dysbindin, a susceptibility gene for schizophrenia. Numakawa T, etal., Hum Mol Genet. 2004 Nov 1;13(21):2699-708. Epub 2004 Sep 2.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Dysbindin is a potent inducer of RhoA-SRF-mediated cardiomyocyte hypertrophy. Rangrez AY, etal., J Cell Biol. 2013 Nov 25;203(4):643-56. doi: 10.1083/jcb.201303052.
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Schwab SG, etal., Am J Hum Genet 2003 Jan;72(1):185-90. Epub 2002 Dec 9.
14. Direct interaction of Dysbindin with the AP-3 complex via its mu subunit. Taneichi-Kuroda S, etal., Neurochem Int. 2009 Jun;54(7):431-8. doi: 10.1016/j.neuint.2009.01.014. Epub 2009 Jan 31.
15. Upregulation of dysbindin in temporal lobe epileptic foci of human and experimental animals. Zhang Y, etal., Synapse. 2012 Jul;66(7):622-9. doi: 10.1002/syn.21548. Epub 2012 Mar 30.
Additional References at PubMed
PMID:1936982   PMID:11316798   PMID:12477932   PMID:14688250   PMID:15102850   PMID:15489334   PMID:16288221   PMID:16448387   PMID:16980328   PMID:17182842   PMID:18504299   PMID:19094965  
PMID:19546860   PMID:19887632   PMID:21998198   PMID:22203680   PMID:25297099  


Genomics

Comparative Map Data
Dtnbp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21719,685,218 - 19,776,668 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1719,685,215 - 19,776,661 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1719,569,853 - 19,660,683 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01721,173,678 - 21,264,514 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01719,496,978 - 19,587,817 (+)NCBIRnor_WKY
Rnor_6.01720,090,136 - 20,182,332 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1720,090,246 - 20,182,206 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01722,105,208 - 22,193,087 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera1719,386,624 - 19,477,026 (+)NCBICelera
Cytogenetic Map17p14NCBI
DTNBP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38615,522,807 - 15,663,058 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl615,522,807 - 15,663,058 (-)EnsemblGRCh38hg38GRCh38
GRCh37615,523,038 - 15,663,289 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36615,631,017 - 15,771,250 (-)NCBINCBI36Build 36hg18NCBI36
Build 34615,631,019 - 15,771,250NCBI
Celera616,760,985 - 16,901,244 (-)NCBICelera
Cytogenetic Map6p22.3NCBI
HuRef615,470,266 - 15,609,971 (-)NCBIHuRef
CHM1_1615,525,522 - 15,665,696 (-)NCBICHM1_1
T2T-CHM13v2.0615,395,977 - 15,536,251 (-)NCBIT2T-CHM13v2.0
Dtnbp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391345,075,552 - 45,155,614 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1345,075,551 - 45,155,623 (-)EnsemblGRCm39 Ensembl
GRCm381344,922,079 - 45,002,096 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1344,922,075 - 45,002,147 (-)EnsemblGRCm38mm10GRCm38
MGSCv371345,017,448 - 45,097,465 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361344,933,051 - 45,013,068 (-)NCBIMGSCv36mm8
Celera1345,997,733 - 46,077,631 (-)NCBICelera
Cytogenetic Map13A5NCBI
cM Map1321.73NCBI
Dtnbp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955590281,704 - 386,189 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955590276,143 - 382,812 (+)NCBIChiLan1.0ChiLan1.0
DTNBP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1615,741,698 - 15,887,039 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl615,741,698 - 15,887,256 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0615,377,263 - 15,523,317 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
DTNBP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13514,738,025 - 14,862,609 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3514,738,029 - 14,864,169 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3514,686,008 - 14,811,763 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03514,835,041 - 14,960,915 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3514,833,870 - 14,961,018 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13514,660,216 - 14,785,689 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03514,712,028 - 14,837,283 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03516,038,025 - 16,163,457 (-)NCBIUU_Cfam_GSD_1.0
Dtnbp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049469,804,409 - 9,943,254 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049365521,787,687 - 1,926,516 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DTNBP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl711,600,795 - 11,720,318 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1711,602,470 - 11,720,156 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2712,191,535 - 12,309,282 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DTNBP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11756,500,523 - 56,650,925 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1756,500,574 - 56,651,491 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604415,563,141 - 15,713,959 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dtnbp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475610,810,413 - 10,942,034 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475610,810,368 - 10,932,801 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dtnbp1
439 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:22
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000074600
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
9590316Scort21Serum corticosterone level QTL 214.750.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17122871563Rat
10401807Kidm52Kidney mass QTL 52kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17131701463Rat
70184BpQTLcluster14Blood pressure QTL cluster 143.38arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)17131990913Rat
631207Niddm41Non-insulin dependent diabetes mellitus QTL 41blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)17137830672Rat
1354658Spl8Serum phospholipid level QTL 83.8blood VLDL phospholipid amount (VT:0010507)blood very low density lipoprotein phospholipid level (CMO:0001571)17160781592Rat
1354581Bp247Blood pressure QTL 2474.5arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)17169599340Rat
1354662Rf49Renal function QTL 492.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)17169599340Rat
1641902Colcr7Colorectal carcinoma resistance QTL 73.350.0044intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)17211514921881669Rat
1300123Bp194Blood pressure QTL 1942.82arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)17211514934551001Rat
631499Stl1Serum triglyceride level QTL 13.6blood triglyceride amount (VT:0002644)blood triglyceride level (CMO:0000118)17327139827389946Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)17429913021293263Rat
2324619Coatc4Coat color QTL 40.001coat/hair pigmentation trait (VT:0010463)pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)17429913021293263Rat
1354613Kidm14Kidney mass QTL 146.2kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)17429913035837242Rat
1354596Bw32Body weight QTL 324.5body mass (VT:0001259)body weight (CMO:0000012)17429913060781592Rat
1354630Cm34Cardiac mass QTL 348.7heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)17429913069599340Rat
1354638Insul1Insulin level QTL 14.8blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)17429913069599340Rat
1354651Lmblg2Limb length QTL 26tibia length (VT:0004357)tibia length (CMO:0000450)17429913069599340Rat
2293648Bmd31Bone mineral density QTL 314.50.0001femur size trait (VT:1000369)femoral neck cortical cross-sectional area (CMO:0001702)17435448727028127Rat
2293664Bmd28Bone mineral density QTL 285.10.0001femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)17435448727028127Rat
2303627Vencon8Ventilatory control QTL 80.001respiration trait (VT:0001943)tidal volume (CMO:0000222)17452803849528038Rat
10054088Scort28Serum corticosterone level QTL 282.040.0102blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)17452803849528038Rat
2303561Bw91Body weight QTL 912body mass (VT:0001259)body weight (CMO:0000012)17886846253868462Rat
1582199Insul5Insulin level QTL 53.40.0119blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)17920136523653323Rat
1582208Kidm32Kidney mass QTL 323.90.0018kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)17920136523653323Rat
1582224Epfw4Epididymal fat weight QTL 43.50.0058epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)17920136523653323Rat
1582225Bw67Body weight QTL 676.20.0001body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582226Bw64Body weight QTL 644.20.0017body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582241Bw70Body weight QTL 704.60.0003body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582245Bw73Body weight QTL 734.60.0004body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
1582258Bw76Body weight QTL 764.60.0005body mass (VT:0001259)body weight (CMO:0000012)17920136523653323Rat
2300002Iddm36Insulin dependent diabetes mellitus QTL 361.98blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)17999128640540197Rat
1549900Iddm20Insulin dependent diabetes mellitus QTL 203.7pancreas integrity trait (VT:0010560)percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)171398677321975515Rat
1331720Rf43Renal function QTL 432.881kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)171533061323017269Rat
1331765Hrtrt15Heart rate QTL 154.094heart pumping trait (VT:2000009)heart rate (CMO:0000002)171533061355836425Rat
1354640Scl32Serum cholesterol level QTL 325.4blood HDL cholesterol amount (VT:0000184)blood high density lipoprotein cholesterol level (CMO:0000052)171578159260781592Rat
1354659Scl68Serum cholesterol level QTL 683.9blood VLDL cholesterol amount (VT:0005144)blood very low density lipoprotein cholesterol level (CMO:0000648)171578159260781592Rat
7394837Memor18Memory QTL 18exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)171864018263640182Rat

Markers in Region
D17Got123  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1719,438,366 - 19,438,535UniSTS
RH 3.4 Map17238.9UniSTS
RH 3.4 Map17238.9RGD
RH 2.0 Map17180.6RGD
RH129878  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21719,776,508 - 19,776,658 (+)MAPPERmRatBN7.2
Rnor_6.01720,182,180 - 20,182,329NCBIRnor6.0
Rnor_5.01722,192,935 - 22,193,084UniSTSRnor5.0
Celera1719,476,874 - 19,477,023UniSTS
RH 3.4 Map17248.3UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 37 57 41 19 41 8 11 74 35 41 11 8
Low 6
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000074600   ⟹   ENSRNOP00000067149
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,685,319 - 19,776,649 (+)Ensembl
Rnor_6.0 Ensembl1720,090,246 - 20,182,206 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102493   ⟹   ENSRNOP00000091788
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,685,218 - 19,776,658 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111857   ⟹   ENSRNOP00000082433
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,686,545 - 19,776,661 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000115732   ⟹   ENSRNOP00000081366
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1719,685,215 - 19,732,665 (+)Ensembl
RefSeq Acc Id: NM_001037664   ⟹   NP_001032753
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,685,218 - 19,776,661 (+)NCBI
Rnor_6.01720,090,136 - 20,182,332 (+)NCBI
Rnor_5.01722,105,208 - 22,193,087 (+)NCBI
Celera1719,386,624 - 19,477,026 (+)RGD
Sequence:
RefSeq Acc Id: XM_039096045   ⟹   XP_038951973
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,685,483 - 19,776,668 (+)NCBI
RefSeq Acc Id: XM_039096046   ⟹   XP_038951974
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,685,498 - 19,776,666 (+)NCBI
RefSeq Acc Id: XM_039096047   ⟹   XP_038951975
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,738,267 - 19,776,668 (+)NCBI
RefSeq Acc Id: XM_039096048   ⟹   XP_038951976
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,705,220 - 19,776,668 (+)NCBI
RefSeq Acc Id: XM_039096049   ⟹   XP_038951977
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21719,738,301 - 19,776,666 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001032753   ⟸   NM_001037664
- UniProtKB: Q6GX90 (UniProtKB/Swiss-Prot),   Q5M834 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067149   ⟸   ENSRNOT00000074600
RefSeq Acc Id: XP_038951973   ⟸   XM_039096045
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038951974   ⟸   XM_039096046
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038951976   ⟸   XM_039096048
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038951975   ⟸   XM_039096047
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038951977   ⟸   XM_039096049
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000091788   ⟸   ENSRNOT00000102493
RefSeq Acc Id: ENSRNOP00000081366   ⟸   ENSRNOT00000115732
RefSeq Acc Id: ENSRNOP00000082433   ⟸   ENSRNOT00000111857

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M834-F1-model_v2 AlphaFold Q5M834 1-352 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700375
Promoter ID:EPDNEW_R10896
Type:single initiation site
Name:Dtnbp1_1
Description:Dysbindin
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01720,090,281 - 20,090,341EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1590759 AgrOrtholog
BioCyc Gene G2FUF-9848 BioCyc
Ensembl Genes ENSRNOG00000048719 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000067149.3 UniProtKB/TrEMBL
  ENSRNOP00000081366.1 UniProtKB/TrEMBL
  ENSRNOP00000082433.1 UniProtKB/TrEMBL
  ENSRNOP00000091788 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074600.3 UniProtKB/TrEMBL
  ENSRNOT00000102493 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000111857.1 UniProtKB/TrEMBL
  ENSRNOT00000115732.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7379090 IMAGE-MGC_LOAD
InterPro Dysbindin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:641528 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109105 IMAGE-MGC_LOAD
NCBI Gene 641528 ENTREZGENE
PANTHER PTHR16294 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Dysbindin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dtnbp1 PhenoGen
UniProt A0A8I5ZUW2_RAT UniProtKB/TrEMBL
  A0A8I6G7E8_RAT UniProtKB/TrEMBL
  DTBP1_RAT UniProtKB/Swiss-Prot
  M0RC42_RAT UniProtKB/TrEMBL
  Q5M834 ENTREZGENE
  Q6GX90 ENTREZGENE
UniProt Secondary Q6GX90 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-03-20 Dtnbp1  dystrobrevin binding protein 1  Dtnbp1  distrobrevin binding protein 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 Dtnbp1  distrobrevin binding protein 1      Symbol and Name status set to provisional 70820 PROVISIONAL