Gene: Steap4 (STEAP4 metalloreductase) Rattus norvegicus
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Symbol: Steap4
Name: STEAP4 metalloreductase
Description: ENCODES a protein that exhibits cupric reductase activity (ortholog); electron transfer activity (ortholog); FAD binding (ortholog); INVOLVED IN copper ion import (ortholog); fat cell differentiation (ortholog); iron ion import across cell outer membrane (ortholog); ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); pleomorphic xanthoastrocytoma (ortholog); Prostatic Neoplasms (ortholog); FOUND IN endosome (ortholog); Golgi apparatus (ortholog); integral component of membrane (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane
AGR Description: Predicted to have FAD binding activity, heme binding activity, and oxidoreductase activity; predicted to be involved in several processes, including cation transport, fat cell differentiation, and oxidation-reduction process; predicted to localize to the cytoplasm, integral component of membrane, and plasma membrane; orthologous to human STEAP4 (STEAP4 metalloreductase).
Merged Description: Predicted to have FAD binding activity, heme binding activity, and oxidoreductase activity; predicted to be involved in several processes, including cation transport, fat cell differentiation, and oxidation-reduction process; predicted to localize to the cytoplasm, integral component of membrane, and plasma membrane; orthologous to human STEAP4 (STEAP4 metalloreductase); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Ab1-219; LOC499991; metalloreductase STEAP4; six-transmembrane epithelial antigen of prostate 4; STEAP family member 4
Orthologs:
Homo sapiens (human) : STEAP4 (STEAP4 metalloreductase)  HGNC  Alliance
Mus musculus (house mouse) : Steap4 (STEAP family member 4)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Steap4 (STEAP4 metalloreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : STEAP4 (STEAP4 metalloreductase)
Canis lupus familiaris (dog) : STEAP4 (STEAP4 metalloreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Steap4 (STEAP4 metalloreductase)
Sus scrofa (pig) : STEAP4 (STEAP4 metalloreductase)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0423,112,682 - 23,135,354 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0423,040,108 - 23,062,780 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4422,688,597 - 22,711,432 (-)NCBIRGSC3.4rn4RGSC3.4
Celera421,558,227 - 21,580,908 (-)NCBICelera
Cytogenetic Map4q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Steap4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1560331
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2019-04-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.