Ogn (osteoglycin) - Rat Genome Database

Name: Ogn
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ogn (osteoglycin) Rattus norvegicus

Analyze

Symbol:

Ogn

Name:

osteoglycin

RGD ID:

1308171

Description:

Predicted to enable growth factor activity. Involved in negative regulation of smooth muscle cell proliferation. Predicted to be located in endoplasmic reticulum. Orthologous to human OGN (osteoglycin); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC291015; mimecan; NEWGENE_1308171

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OGN (osteoglycin)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ogn (osteoglycin)	HGNC	Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):	Ogn (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OGN (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OGN (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ogn (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OGN (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	OGN (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ogn (osteoglycin)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	OGN (osteoglycin)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Mus musculus (house mouse):	Ogn (osteoglycin)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Danio rerio (zebrafish):	ogna	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|sonicParanoid)
Danio rerio (zebrafish):	ognb	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	17	15,032,069 - 15,052,626 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	17	15,032,069 - 15,052,739 (-)	Ensembl
Rnor_6.0	17	14,607,442 - 14,628,274 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	14,607,442 - 14,627,937 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,447,716 - 15,467,359 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	17,506,166 - 17,527,131 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	20,987,029 - 21,007,525 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	17	20,987,030 - 21,007,504 (-)	NCBI
Celera	17	14,763,600 - 14,783,780 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

hereditary sensory and autonomic neuropathy type 1 (ISO)

hereditary sensory neuropathy (ISO)

Neoplasm Metastasis (ISO)

spinal muscular atrophy with lower extremity predominance 2A (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(2,4,5-trichlorophenoxy)acetic acid (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2,4,6-tribromophenol (ISO)

2,4-diaminotoluene (ISO)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

2,6-dinitrotoluene (EXP)

2-hydroxypropanoic acid (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,7-dihydropurine-6-thione (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

7,12-dimethyltetraphene (EXP)

acrylamide (EXP)

aldrin (ISO)

antirheumatic drug (ISO)

arsenous acid (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt atom (ISO)

copper(II) sulfate (ISO)

coumarin (EXP)

crocidolite asbestos (ISO)

Cuprizon (EXP)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dibutyl phthalate (ISO)

dioxygen (EXP,ISO)

diuron (EXP)

doxorubicin (ISO)

endosulfan (EXP)

furan (EXP)

gentamycin (EXP)

glycidol (EXP)

glyphosate (EXP)

graphene oxide (ISO)

indole-3-methanol (EXP)

indometacin (ISO)

mercaptopurine (EXP)

methotrexate (ISO)

N-nitrosodiethylamine (ISO)

nickel atom (ISO)

orphenadrine (EXP)

oxaliplatin (EXP)

ozone (ISO)

paclitaxel (ISO)

paracetamol (EXP)

paraquat (EXP)

phenylephrine (EXP)

potassium dichromate (ISO)

purine-6-thiol (EXP)

rac-lactic acid (ISO)

rotenone (EXP)

serpentine asbestos (ISO)

silver atom (ISO)

silver(0) (ISO)

sirolimus (EXP)

sodium arsenite (EXP,ISO)

sodium fluoride (ISO)

sulforaphane (ISO)

tacrolimus hydrate (EXP,ISO)

tetrachloromethane (EXP,ISO)

titanium dioxide (ISO)

topotecan (EXP)

triclosan (ISO)

trimellitic anhydride (ISO)

troglitazone (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

articular cartilage development (IBA)

bone development (IBA)

negative regulation of smooth muscle cell proliferation (IMP)

signal transduction (IEA)

Cellular Component

endoplasmic reticulum (ISO)

extracellular matrix (IBA)

Molecular Function

growth factor activity (IEA)

protein binding (ISO)

References

References - curated


1.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Gu XS, etal., Mol Cell Biochem. 2011 Jun;352(1-2):309-16. doi: 10.1007/s11010-011-0767-8. Epub 2011 Apr 26.
3.	MGD data from the GO Consortium
4.	RGD automated data pipeline
5.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:18443592	PMID:20551380	PMID:23533145	PMID:24006456	PMID:24769233	PMID:27068509	PMID:27559042	PMID:29990505	PMID:33215216

Genomics

Comparative Map Data

Ogn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	17	15,032,069 - 15,052,626 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	17	15,032,069 - 15,052,739 (-)	Ensembl
Rnor_6.0	17	14,607,442 - 14,628,274 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	17	14,607,442 - 14,627,937 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0 Ensembl	17	15,447,716 - 15,467,359 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	17	17,506,166 - 17,527,131 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	17	20,987,029 - 21,007,525 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	17	20,987,030 - 21,007,504 (-)	NCBI
Celera	17	14,763,600 - 14,783,780 (-)	NCBI		Celera
Cytogenetic Map	17	p14	NCBI

OGN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	9	92,383,268 - 92,404,699 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	9	92,383,268 - 92,404,696 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	9	95,145,550 - 95,166,981 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	9	94,186,070 - 94,206,758 (-)	NCBI	NCBI36		hg18	NCBI36
Celera	9	65,588,282 - 65,608,970 (-)	NCBI
Cytogenetic Map	9	q22.31	NCBI
HuRef	9	64,823,710 - 64,844,399 (-)	NCBI		HuRef
CHM1_1	9	95,292,689 - 95,313,376 (-)	NCBI		CHM1_1

Ogn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	13	49,761,491 - 49,777,977 (+)	NCBI	GRCm39		mm39
GRCm39 Ensembl	13	49,761,522 - 49,777,977 (+)	Ensembl
GRCm38	13	49,608,015 - 49,624,501 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	13	49,608,046 - 49,624,501 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	13	49,703,440 - 49,719,869 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	13	49,620,008 - 49,636,437 (+)	NCBI			mm8
Celera	13	50,698,836 - 50,715,265 (+)	NCBI		Celera
Cytogenetic Map	13	A5	NCBI

Ogn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955515	5,372,034 - 5,389,954 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955515	5,372,225 - 5,389,954 (+)	NCBI	ChiLan1.0	ChiLan1.0

OGN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	9	91,578,833 - 91,600,741 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	9	91,578,833 - 91,600,738 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	9	63,505,165 - 63,527,761 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

OGN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	1	98,939,374 - 98,959,173 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	1	98,939,429 - 98,957,543 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	1	99,333,213 - 99,353,015 (+)	NCBI
ROS_Cfam_1.0	1	99,556,194 - 99,575,993 (+)	NCBI
ROS_Cfam_1.0 Ensembl	1	99,555,768 - 99,627,336 (+)	Ensembl
UMICH_Zoey_3.1	1	99,169,271 - 99,189,070 (+)	NCBI
UNSW_CanFamBas_1.0	1	98,904,553 - 98,924,354 (+)	NCBI
UU_Cfam_GSD_1.0	1	99,661,321 - 99,681,130 (+)	NCBI

Ogn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404944	7,813,284 - 7,827,902 (-)	NCBI
SpeTri2.0	NW_004936487	2,029,755 - 2,043,242 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OGN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	42,116,531 - 42,135,817 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	42,116,521 - 42,135,940 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	43,250,528 - 43,259,180 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OGN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	12	102,908,482 - 102,928,956 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	12	102,908,479 - 102,928,827 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666038	91,180,673 - 91,201,156 (-)	NCBI	Vero_WHO_p1.0

Ogn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624868	3,950,145 - 3,974,359 (+)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

RH139253

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	17	15,032,432 - 15,032,646 (+)	MAPPER	mRatBN7.2
Rnor_6.0	17	14,607,806 - 14,608,019	NCBI	Rnor6.0
Rnor_6.0	17	15,448,080 - 15,448,293	NCBI	Rnor6.0
Rnor_5.0	17	17,506,530 - 17,506,743	UniSTS	Rnor5.0
Rnor_5.0	17	16,660,127 - 16,660,340	UniSTS	Rnor5.0
RGSC_v3.4	17	20,987,393 - 20,987,606	UniSTS	RGSC3.4
Celera	17	14,763,964 - 14,764,177	UniSTS
RH 3.4 Map	17	179.4	UniSTS
Cytogenetic Map	17	p14	UniSTS

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
9590316	Scort21	Serum corticosterone level QTL 21	4.75	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	1	22871563	Rat
10401807	Kidm52	Kidney mass QTL 52			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	1	31701463	Rat
70184	BpQTLcluster14	Blood pressure QTL cluster 14	3.38		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	17	1	31990913	Rat
631207	Niddm41	Non-insulin dependent diabetes mellitus QTL 41			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	17	1	37830672	Rat
1354658	Spl8	Serum phospholipid level QTL 8	3.8		blood VLDL phospholipid amount (VT:0010507)	blood very low density lipoprotein phospholipid level (CMO:0001571)	17	1	60781592	Rat
1354581	Bp247	Blood pressure QTL 247	4.5		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	17	1	69599340	Rat
1354662	Rf49	Renal function QTL 49	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	17	1	69599340	Rat
1641902	Colcr7	Colorectal carcinoma resistance QTL 7	3.35	0.0044	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	17	2115149	21881669	Rat
1300123	Bp194	Blood pressure QTL 194	2.82		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	17	2115149	34551001	Rat
631499	Stl1	Serum triglyceride level QTL 1	3.6		blood triglyceride amount (VT:0002644)	blood triglyceride level (CMO:0000118)	17	3271398	27389946	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	17	4299130	21293263	Rat
2324619	Coatc4	Coat color QTL 4		0.001	coat/hair pigmentation trait (VT:0010463)	pigmented dorsal coat/hair area to total dorsal coat/hair area ratio (CMO:0001811)	17	4299130	21293263	Rat
1354613	Kidm14	Kidney mass QTL 14	6.2		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	17	4299130	35837242	Rat
1354596	Bw32	Body weight QTL 32	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	17	4299130	60781592	Rat
1354630	Cm34	Cardiac mass QTL 34	8.7		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	17	4299130	69599340	Rat
1354638	Insul1	Insulin level QTL 1	4.8		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	17	4299130	69599340	Rat
1354651	Lmblg2	Limb length QTL 2	6		tibia length (VT:0004357)	tibia length (CMO:0000450)	17	4299130	69599340	Rat
2293648	Bmd31	Bone mineral density QTL 31	4.5	0.0001	femur size trait (VT:1000369)	femoral neck cortical cross-sectional area (CMO:0001702)	17	4354487	27028127	Rat
2293664	Bmd28	Bone mineral density QTL 28	5.1	0.0001	femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	17	4354487	27028127	Rat
2303627	Vencon8	Ventilatory control QTL 8		0.001	respiration trait (VT:0001943)	tidal volume (CMO:0000222)	17	4528038	49528038	Rat
10054088	Scort28	Serum corticosterone level QTL 28	2.04	0.0102	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	17	4528038	49528038	Rat
1581553	Pur14	Proteinuria QTL 14	5.3	0.0001	total urine protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	17	7979968	16317111	Rat
2303561	Bw91	Body weight QTL 91	2		body mass (VT:0001259)	body weight (CMO:0000012)	17	8868462	53868462	Rat
1582199	Insul5	Insulin level QTL 5	3.4	0.0119	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	17	9201365	23653323	Rat
1582208	Kidm32	Kidney mass QTL 32	3.9	0.0018	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	17	9201365	23653323	Rat
1582224	Epfw4	Epididymal fat weight QTL 4	3.5	0.0058	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	17	9201365	23653323	Rat
1582225	Bw67	Body weight QTL 67	6.2	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582226	Bw64	Body weight QTL 64	4.2	0.0017	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582241	Bw70	Body weight QTL 70	4.6	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582245	Bw73	Body weight QTL 73	4.6	0.0004	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
1582258	Bw76	Body weight QTL 76	4.6	0.0005	body mass (VT:0001259)	body weight (CMO:0000012)	17	9201365	23653323	Rat
2300002	Iddm36	Insulin dependent diabetes mellitus QTL 36	1.98		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	17	9991286	40540197	Rat
1549900	Iddm20	Insulin dependent diabetes mellitus QTL 20	3.7		pancreas integrity trait (VT:0010560)	percentage of study population developing diabetes mellitus during a period of time (CMO:0001114)	17	13986773	21975515	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	901
Count of miRNA genes:	285
Interacting mature miRNAs:	357
Transcripts:	ENSRNOT00000020532, ENSRNOT00000072490
Prediction methods:	Microtar, Miranda, Pita, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	33	16		19		8	10	34	32	32	11	8
Low	1	30	41	41		41		1	49	25	30
Below cutoff		8	20	20		20			40	2	6

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106103	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008771490	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC120310	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213759	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ221052	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000020532 ⟹ ENSRNOP00000020532

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	15,032,069 - 15,052,566 (-)	Ensembl
Rnor_6.0 Ensembl	17	14,607,442 - 14,627,937 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000072490 ⟹ ENSRNOP00000065601

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	17	15,448,986 - 15,467,320 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000093561 ⟹ ENSRNOP00000076332

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	17	15,032,072 - 15,052,739 (-)	Ensembl
Rnor_6.0 Ensembl	17	15,447,716 - 15,467,359 (-)	Ensembl

RefSeq Acc Id:

NM_001106103 ⟹ NP_001099573

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	17	15,032,069 - 15,052,566 (-)	NCBI
Rnor_6.0	17	14,607,442 - 14,627,937 (-)	NCBI
Rnor_5.0	17	17,506,166 - 17,527,131 (-)	NCBI
RGSC_v3.4	17	20,987,029 - 21,007,525 (-)	RGD
Celera	17	14,763,600 - 14,783,780 (-)	RGD

Sequence:

show sequence

TCAGCAGTTTGAAGCAATTCCACAGCTTTGCTCATTCACTCTCCCACTTGGGACTAATGCACAG
GAAAACTCAGGGACTTCAACCAGATACTACGGGAAAAAAGAGGTTTGTTCCACAGTCATCAGGT
CAGTAATTTCCTAACTTCTAGTCACCTTGTGTTTGCTGCAATGAAGACTGTGCATCCTACGCTT
CTCCTGCTATTGTTCGTGCCTCTGACACAGCAAACACCACAAACTCAGCTGGACTCACACGTTA
ACTCTAAGTATGGAACAGATAATTCTGAAGAAACCAAATTTATCCAGGATTATGAAGATAAATA
CCTGGATGGGAAAAATATTAAGGAAAAAGAAACTATGATAATTCCTGATGAGAAAAGTCTTCAG
TTACAAAAAGATGAAGTCATACCATCAGTGCCCACCAAGAAAGAAAATGATGAAATGCCCACAT
GCCTGTTGTGTGTCTGTTTAAGTGGCTCTGTCTACTGTGAAGAAGTTGACATTGATGCTGTACC
ACCACTGCCAAAAGAATCAGCTTATCTTTATGCACGATTCAACAAAATTAAAAAGCTGACTGCC
AAGGATTTTGCAGACATGCCTAACTTAAGAAGACTTGATTTTACGGGAAATTTGATAGAAGACA
TAGAAGATGGTACTTTTTCAAAACTTTCTCTGTTAGAAGAACTTACACTTGCTGAAAACCAACT
ACTAAGACTTCCAGTTCTTCCTCCAAAGCTTACTTTACTCAATGCCAAATACAACAAAATCAAG
AGTAAAGGAATTAAAGCAAACACATTCAAAAAACTGAATAAACTCTCTTTTCTCTATTTGGACC
ATAATGATCTGGAATCTGTGCCTCCTAATTTACCAGAAAGTCTACGTGTAATTCACCTTCAGTT
TAACAGCATATCTTCAATTACCGATGATACATTCTGCAAGGCTAATGACACTCGGTACATTCGG
GAGCGCATGGAAGAGATCCGCCTGGAGGGCAATCCGATTGCTCTGGGAAAGCATCCAAACAGCT
TTATCTGCTTAAAAAGATTACCCACAGGGTCATACTTTTAACCTTCATCAGTGCATTTATAATC
TGAGGTACATGCACCTGATGTCTAAAGGAACATACACATTAGTTTAACATTATCGTTTTATCTC
ACTATGATGGAATCTTATGTTTTAACAAAGATGTCCAAATTTCTGAAATGTAATTATAAAAATA
ATCCAGCCTGAATCTCCTAGTTCAAAACAAAGTAACGTGAACATAAACAGCATTAGAAACCTCC
GTGGTTGTAGCAGACCGCCATCTAAACAGTGCGCTTTTACACAAACACTCGCTCACACACACCA
TTGCCATGACTAATGAAGTCAGAGAATTCCAAAAAAACTCTCAACTTTGTCTTCCTTAACATTT
ACTGTGTCTCAAAGGCATTTAAGACAGATGCTCCAGAACCTGTGCACAGCCAAGTGCTCCCAGT
GACCTTCCCCTGACTCTATGACTCACCGGTGTTCTCTGTAAAGCAGAAACTTACTTTCTGTCCA
GGCAGCTACTTCACTGTATTTCTCACTTAGCCTAAGGAAAGGGGAGCCACATGTAGGCAATCAT
TTCCAGAGGAAGTAAAATTTTGCTCTTTGGTACAGAGCCAACTTAGCAAAGTTCAATCTCCTGC
TTTGTGGTCACGTGCATAGTCTTTAGTCAATTACTTAAAAAAAACTTTGTCAGAAAAAAAGTAA
AATTCCTACCCATTTCTCAAAGAATAAGGTTCCTTCGCTTTAAAGATTCTTATTCCAATTTTAG
TGTATGTGTTGCGAAAGCAAGCACAAAGATTCTGAAATATGAAATTAGCTATACACTTTCTCAC
AGTATATTTATTCAAATATAAGAAATGAAAACAAAATACCCCATTATGCTGTGTGCAGTTTCAC
CTGTACATACATGTTCACCTGAACAAACTGAATATTCCCATTCTAGCCCAAGAGTACCATTTCT
CACTGGCCAAGATCTCTACATATATGTAATAGTGAAAACCCAGTCTCCAGTCTGATAGTGAGAG
CGATGCACACTAAGGTTCCAAACGGAACTGCAGAGGAAGGGCATAGCCCACTCACAAATATTAC
TTTATTACTTTGGTGATGAATACAAAATGATCAGTGTCTTAGAAATTATTCATCTTTTATATAT
AAAAGTACCAATATCATTTCCACTATAAGCTATACATCAGACTCTACATGTTCATCCTAGAACA
TCCATTTTAAGCATTTGGTTGTTTTGTTTCAACCCAGACTGACCATTCTCTCATCTGTTAGGGT
TAACCCCAGATGAAACTTTTCATCATTAAAGCATCTGTGATCTATAAGGCCACAACTATTGCTC
TAATAATGTCTACTAGTTTATTTGTTTTTATAAGTTAATTATAGTAACTTTATCTCTCTGTATC
ATTTTGTTCGCAGGCCTCATTTTCTCTGACTGAATGCTCACCAAGAGCACTGAACACAGTTCTA
CTTTTATGATACTTAATACCATATTTCAGCTAAATATACAATAAACACTGTAAAATCTATCCAA
ATAGAAGGGTTCTGTTTATATGGAAAAAACAAATTAGTATAGTCTTGAATAAATCAACAGAAAT
AAAGTGACAAGTTTAAGAACGGTCAA

hide sequence

RefSeq Acc Id:

XM_008771490 ⟹ XP_008769712

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	17	15,032,069 - 15,052,626 (-)	NCBI
Rnor_6.0	17	14,607,442 - 14,628,274 (-)	NCBI

Sequence:

show sequence

TTCTCATTAAATTAAGAACAAAGACTATGCTCAGTTTGGTGTTCTATTTCATTCAAAAGTAAAT
GTCTTCTATACCAGAAAGGCACAAAAATAAAGGCCAGATTTTAAAAAGATTTATAAACTAGCAT
TCACTAAAAGATTCGTGCACAGGGTAACAGGGCAGACGGCAGCATGCTGTAGCTGCCCTGGTGC
TGCAACTTCAAGTGTCTTCAGTACATTCTCCCATGTAACACCCTGCAGTTCACCCCGAGAAGGA
ATGTTGGCCAGGACTTCCACCACATGGAATCTGCTGTTGAATTCCACATGGGAGTTAAGCTGCT
GGGCCCTGAAACTTTATTCAGCAGTTTGAAGCAATTCCACAGCTTTGCTCATTCACTCTCCCAC
TTGGGACTAATGCACAGGAAAACTCAGGGACTTCAACCAGATACTACGGTGCCCTGGGAAGATT
TTGACTGCACACAATACCTCTACTCAAGACTTTGGGCATTTAATAAACTTGCCAGCAGTTTTAA
AATTGTTGATGGGGAAAAAAGAGGTTTGTTCCACAGTCATCAGGTCAGTAATTTCCTAACTTCT
AGTCACCTTGTGTTTGCTGCAATGAAGACTGTGCATCCTACGCTTCTCCTGCTATTGTTCGTGC
CTCTGACACAGCAAACACCACAAACTCAGCTGGACTCACACGTTAACTCTAAGTATGGAACAGA
TAATTCTGAAGAAACCAAATTTATCCAGGATTATGAAGATAAATACCTGGATGGGAAAAATATT
AAGGAAAAAGAAACTATGATAATTCCTGATGAGAAAAGTCTTCAGTTACAAAAAGATGAAGTCA
TACCATCAGTGCCCACCAAGAAAGAAAATGATGAAATGCCCACATGCCTGTTGTGTGTCTGTTT
AAGTGGCTCTGTCTACTGTGAAGAAGTTGACATTGATGCTGTACCACCACTGCCAAAAGAATCA
GCTTATCTTTATGCACGATTCAACAAAATTAAAAAGCTGACTGCCAAGGATTTTGCAGACATGC
CTAACTTAAGAAGACTTGATTTTACGGGAAATTTGATAGAAGACATAGAAGATGGTACTTTTTC
AAAACTTTCTCTGTTAGAAGAACTTACACTTGCTGAAAACCAACTACTAAGACTTCCAGTTCTT
CCTCCAAAGCTTACTTTACTCAATGCCAAATACAACAAAATCAAGAGTAAAGGAATTAAAGCAA
ACACATTCAAAAAACTGAATAAACTCTCTTTTCTCTATTTGGACCATAATGATCTGGAATCTGT
GCCTCCTAATTTACCAGAAAGTCTACGTGTAATTCACCTTCAGTTTAACAGCATATCTTCAATT
ACCGATGATACATTCTGCAAGGCTAATGACACTCGGTACATTCGGGAGCGCATGGAAGAGATCC
GCCTGGAGGGCAATCCGATTGCTCTGGGAAAGCATCCAAACAGCTTTATCTGCTTAAAAAGATT
ACCCACAGGGTCATACTTTTAACCTTCATCAGTGCATTTATAATCTGAGGTACATGCACCTGAT
GTCTAAAGGAACATACACATTAGTTTAACATTATCGTTTTATCTCACTATGATGGAATCTTATG
TTTTAACAAAGATGTCCAAATTTCTGAAATGTAATTATAAAAATAATCCAGCCTGAATCTCCTA
GTTCAAAACAAAGTAACGTGAACATAAACAGCATTAGAAACCTCCGTGGTTGTAGCAGACCGCC
ATCTAAACAGTGCGCTTTTACACAAACACTCGCTCACACACACCATTGCCATGACTAATGAAGT
CAGAGAATTCCAAAAAAACTCTCAACTTTGTCTTCCTTAACATTTACTGTGTCTCAAAGGCATT
TAAGACAGATGCTCCAGAACCTGTGCACAGCCAAGTGCTCCCAGTGACCTTCCCCTGACTCTAT
GACTCACCGGTGTTCTCTGTAAAGCAGAAACTTACTTTCTGTCCAGGCAGCTACTTCACTGTAT
TTCTCACTTAGCCTAAGGAAAGGGGAGCCACATGTAGGCAATCATTTCCAGAGGAAGTAAAATT
TTGCTCTTTGGTACAGAGCCAACTTAGCAAAGTTCAATCTCCTGCTTTGTGGTCACGTGCATAG
TCTTTAGTCAATTACTTAAAAAAAACTTTGTCAGAAAAAAAGTAAAATTCCTACCCATTTCTCA
AAGAATAAGGTTCCTTCGCTTTAAAGATTCTTATTCCAATTTTAGTGTATGTGTTGCGAAAGCA
AGCACAAAGATTCTGAAATATGAAATTAGCTATACACTTTCTCACAGTATATTTATTCAAATAT
AAGAAATGAAAACAAAATACCCCATTATGCTGTGTGCAGTTTCACCTGTACATACATGTTCACC
TGAACAAACTGAATATTCCCATTCTAGCCCAAGAGTACCATTTCTCACTGGCCAAGATCTCTAC
ATATATGTAATAGTGAAAACCCAGTCTCCAGTCTGATAGTGAGAGCAATGCACACTAAGGTTCC
AAACGGAACTGCAGAGGAAGGGCATAGCCCACTCACAAATATTACTTTATTACTTTGGTGATGA
ATACAAAATGATCAGTGTCTTAGAAATTATTCATCTTTTATATATAAAAGTACCAATATCATTT
CCACTATAAGCTATACATCAGACTCTACATGTTCATCCTAGAACATCCATTTTAAGCATTTGGT
TGTTTTGTTTCAACCCAGACTGACCATTCTCTCATCTGTTAGGGTTAACCCCAGATGAAACTTT
TCATCATTAAAGCATCTGTGATCTATAAGGCCACAACTATTGCTCTAATAATGTCTACTAGTTT
ATTTGTTTTTATAAGTTAATTATAGTAACTTTATCTCTCTGTATCATTTTGTTCGCAGGCCTCA
TTTTCTCTGACTGAATGCTCACCAAGAGCACTGAACACAGTTCTACTTTTATGATACTTAATAC
CATATTTCAGCTAAATATACAATAAACACTGTAAAATCTATCCAAATAGAAGGGTTCTGTTTAT
ATGGAAAAAACAAATTAGTATAGTCTTGAATAAATCAACAGAAATAAAGTGACAAGTTTAAGAA
CGGTCAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099573	(Get FASTA)	NCBI Sequence Viewer
	XP_008769712	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	EDL98110	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_001099573 ⟸ NM_001106103
- Peptide Label:	precursor
- UniProtKB:	D3ZVB7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MKTVHPTLLLLLFVPLTQQTPQTQLDSHVNSKYGTDNSEETKFIQDYEDKYLDGKNIKEKETMI IPDEKSLQLQKDEVIPSVPTKKENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARF NKIKKLTAKDFADMPNLRRLDFTGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLL NAKYNKIKSKGIKANTFKKLNKLSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSITDDTFCK ANDTRYIRERMEEIRLEGNPIALGKHPNSFICLKRLPTGSYF hide sequence

RefSeq Acc Id:

XP_008769712 ⟸ XM_008771490

- Peptide Label:

isoform X1

- Sequence:

show sequence

MESAVEFHMGVKLLGPETLFSSLKQFHSFAHSLSHLGLMHRKTQGLQPDTTVPWEDFDCTQYLY
SRLWAFNKLASSFKIVDGEKRGLFHSHQVSNFLTSSHLVFAAMKTVHPTLLLLLFVPLTQQTPQ
TQLDSHVNSKYGTDNSEETKFIQDYEDKYLDGKNIKEKETMIIPDEKSLQLQKDEVIPSVPTKK
ENDEMPTCLLCVCLSGSVYCEEVDIDAVPPLPKESAYLYARFNKIKKLTAKDFADMPNLRRLDF
TGNLIEDIEDGTFSKLSLLEELTLAENQLLRLPVLPPKLTLLNAKYNKIKSKGIKANTFKKLNK
LSFLYLDHNDLESVPPNLPESLRVIHLQFNSISSITDDTFCKANDTRYIRERMEEIRLEGNPIA
LGKHPNSFICLKRLPTGSYF

hide sequence

RefSeq Acc Id:

ENSRNOP00000065601 ⟸ ENSRNOT00000072490

RefSeq Acc Id:

ENSRNOP00000076332 ⟸ ENSRNOT00000093561

RefSeq Acc Id:

ENSRNOP00000020532 ⟸ ENSRNOT00000020532

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D3ZVB7-F1-model_v2	AlphaFold	D3ZVB7	1-298	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700342

Promoter ID:

EPDNEW_R10866

Type:

initiation region

Name:

Ogn_1

Description:

osteoglycin

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	17	14,627,935 - 14,627,995	EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)

ACI/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

ACI/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN-Lx/CubMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/NHsdMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BN/SsN (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BUF/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH2/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

BXH3/CubMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

DA/OlaHsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/DuCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

F344/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FHH/EurMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE16/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

FXLE18/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

GK/FarMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB10/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB2/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB20/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB31/IpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

HXB4/IpcvMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LE/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEW/Crl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF10A/StmMcwi (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF11/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1A/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF1C/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF2B/Stm (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF3/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LEXF4/Stm (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LH/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LL/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

LN/MavRrrcAek (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Kwitek
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

M520/NRrrcMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MR/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

MWF/Hsd (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

PVG/Seac (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Japan
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHR/OlalpcvMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SHRSP/A3NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SR/JrHsd (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Envigo
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

SS/JrHsdMcwi (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	MCW
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WAG/RijCrl (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WKY/NCrl (2019)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	Charles River
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

WN/N (2020)

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Platform:	GSPMC-Illumina-NovaSeq6000
Secondary Analysis:	BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder:	NIH
Description:	Dr. Mindy Dwinell - Hybrid rat diversity program

Damaging Variants

Assembly: mRatBN7.2

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
17	15051696	15051697	G	A	snv	LEXF3/Stm (2020), LEXF2B/Stm (2019), LEXF1C/Stm (2019), FXLE16/Stm (2020), LE/Stm (2019), LEXF4/Stm (2020)
17	15052617	15052618	G	C	snv	LEW/Crl (2019), LEXF11/Stm (2020), LEXF1A/Stm (2019), LH/MavRrrcAek (2020), LL/MavRrrcAek (2020), LN/MavRrrcAek (2020), LEXF10A/StmMcwi (2020), SR/JrHsd (2020), SS/JrHsdMcwi (2019), WAG/RijCrl (2020), WN/N (2020), FHH/EurMcwi (2019), F344/Stm (2019), F344/N (2020), F344/NCrl (2019), F344/DuCrl (2019), FXLE18/Stm (2020)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308171	AgrOrtholog
BioCyc Gene	G2FUF-10003	BioCyc
Ensembl Genes	ENSRNOG00000029792	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOG00000047786	Ensembl, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000020532	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOP00000065601	UniProtKB/TrEMBL
	ENSRNOP00000076332	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000020532	ENTREZGENE, UniProtKB/TrEMBL
	ENSRNOT00000072490	UniProtKB/TrEMBL
	ENSRNOT00000093561	ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH	3.80.10.10	UniProtKB/TrEMBL
InterPro	L_dom-like	UniProtKB/TrEMBL
	Leu-rich_rpt	UniProtKB/TrEMBL
	Leu-rich_rpt_typical-subtyp	UniProtKB/TrEMBL
	Mimecan	UniProtKB/TrEMBL
	Mimecan/Epiphycan	UniProtKB/TrEMBL
KEGG Report	rno:291015	UniProtKB/TrEMBL
NCBI Gene	291015	ENTREZGENE
PANTHER	PTHR46269	UniProtKB/TrEMBL
	PTHR46269:SF1	UniProtKB/TrEMBL
Pfam	LRR_8	UniProtKB/TrEMBL
PhenoGen	Ogn	PhenoGen
PROSITE	LRR	UniProtKB/TrEMBL
SMART	LRR_TYP	UniProtKB/TrEMBL
UniProt	D3ZVB7	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Ogn	osteoglycin	NEWGENE_1308171	osteoglycin	Data Merged	737654	PROVISIONAL
2016-08-02	NEWGENE_1308171	osteoglycin			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-04-07	Ogn	osteoglycin	Ogn_predicted	osteoglycin (predicted)	Symbol and Name updated	1299863	APPROVED
2005-01-12	Ogn_predicted	osteoglycin (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD