Gene: Tlx2 (T-cell leukemia homeobox 2) Rattus norvegicus
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Symbol: Tlx2
Name: T-cell leukemia homeobox 2
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and sequence-specific DNA binding activity; predicted to be involved in mesoderm formation, nervous system development, and positive regulation of transcription by RNA polymerase II; predicted to localize to the cytoplasm and nucleus; orthologous to human TLX2 (T cell leukemia homeobox 2); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; C60 fullerene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Hox11L.1; LOC680117; similar to T-cell leukemia homeobox protein 2 (Homeobox protein Hox-11L1) (Homeobox TLX-2) (PMUR10F); T-cell leukemia, homeobox 2
Orthologs:
Homo sapiens (human) : TLX2 (T cell leukemia homeobox 2)  HGNC  Alliance
Mus musculus (house mouse) : Tlx2 (T cell leukemia, homeobox 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tlx2 (T cell leukemia homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TLX2 (T cell leukemia homeobox 2)
Canis lupus familiaris (dog) : TLX2 (T cell leukemia homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tlx2 (T cell leukemia homeobox 2)
Sus scrofa (pig) : TLX2 (T cell leukemia homeobox 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04114,766,401 - 114,768,243 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04178,585,662 - 178,587,437 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44117,279,091 - 117,281,693 (-)NCBIRGSC3.4rn4RGSC3.4
Celera4104,568,477 - 104,570,295 (-)NCBICelera
Cytogenetic Map4q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tlx2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1595506
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.