Vwa8 (von Willebrand factor A domain containing 8) - Rat Genome Database

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Gene: Vwa8 (von Willebrand factor A domain containing 8) Rattus norvegicus
Analyze
Symbol: Vwa8
Name: von Willebrand factor A domain containing 8
RGD ID: 1308772
Description: Predicted to enable ATP hydrolysis activity. Predicted to be located in mitochondrion and peroxisome. Predicted to be active in cytoplasm. Orthologous to human VWA8 (von Willebrand factor A domain containing 8); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC290381; RGD1308772; similar to KIAA0564 protein; von Willebrand factor A domain-containing protein 8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81560,661,764 - 60,985,971 (+)NCBIGRCr8
mRatBN7.21554,252,703 - 54,576,871 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01561,158,510 - 61,467,462 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01561,069,439 - 61,153,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01564,733,018 - 64,817,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01565,106,678 - 65,131,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41559,993,882 - 60,364,838 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11559,950,242 - 60,379,537 (+)NCBI
Celera1553,842,678 - 54,161,011 (+)NCBICelera
Cytogenetic Map15q11-q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8RatDevelopmental Disabilities  ISOVWA8 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental delayClinVarPMID:34660594 and PMID:36937954
Vwa8Ratorofacial cleft  ISOVWA8 (Homo sapiens)8554872ClinVar Annotator: match by term: Nonsyndromic cleft lip palateClinVarPMID:25741868 and PMID:27229527
Vwa8RatRetinitis Pigmentosa 97  ISOVWA8 (Homo sapiens)8554872ClinVar Annotator: match by term: Retinitis pigmentosa 97ClinVarPMID:25741868 and PMID:27229527
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8Ratautistic disorder  ISOVWA8 (Homo sapiens)11554173CTD Direct Evidence: marker/mechanismCTDPMID:20663923
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8RatRetinitis Pigmentosa 97  ISOVWA8 (Homo sapiens)7240710 OMIM 

1 to 20 of 81 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8Rat(+)-schisandrin B multiple interactionsEXP 6480464schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of VWA8 mRNA]CTDPMID:31150632
Vwa8Rat1,2-dimethylhydrazine multiple interactionsISOVwa8 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VWA8 mRNACTDPMID:22206623
Vwa8Rat17beta-estradiol decreases expressionEXP 6480464Estradiol results in decreased expression of VWA8 mRNACTDPMID:32145629
Vwa8Rat2,2',4,4'-Tetrabromodiphenyl ether decreases expressionISOVWA8 (Homo sapiens)64804642 more ...CTDPMID:31675489
Vwa8Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of VWA8 mRNACTDPMID:21215274
Vwa8Rat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOVwa8 (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of VWA8 mRNACTDPMID:31961203
Vwa8Rat2,4,6-tribromophenol increases expressionISOVWA8 (Homo sapiens)64804642 more ...CTDPMID:31675489
Vwa8Rat3,3',5,5'-tetrabromobisphenol A decreases expressionISOVWA8 (Homo sapiens)6480464tetrabromobisphenol A results in decreased expression of VWA8 proteinCTDPMID:31675489
Vwa8Rat4,4'-sulfonyldiphenol increases methylationISOVWA8 (Homo sapiens)6480464bisphenol S results in increased methylation of VWA8 geneCTDPMID:31601247
Vwa8Rat4,4'-sulfonyldiphenol affects expressionISOVWA8 (Homo sapiens)6480464bisphenol S affects the expression of VWA8 proteinCTDPMID:31945527
Vwa8Rataristolochic acid A decreases expressionISOVWA8 (Homo sapiens)6480464aristolochic acid I results in decreased expression of VWA8 mRNACTDPMID:33212167
Vwa8Ratarsane affects methylationISOVWA8 (Homo sapiens)6480464Arsenic affects the methylation of VWA8 geneCTDPMID:25304211
Vwa8Ratarsenic atom affects methylationISOVWA8 (Homo sapiens)6480464Arsenic affects the methylation of VWA8 geneCTDPMID:25304211
Vwa8Ratatrazine affects methylationEXP 6480464Atrazine affects the methylation of VWA8 geneCTDPMID:35440735
Vwa8Ratbenzo[a]pyrene decreases expressionISOVwa8 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of VWA8 mRNACTDPMID:23735875
Vwa8Ratbenzo[a]pyrene decreases methylationISOVwa8 (Mus musculus)6480464Benzo(a)pyrene results in decreased methylation of VWA8 exon and Benzo(a)pyrene results in decreased methylation of VWA8 intronCTDPMID:27901495
Vwa8Ratbenzo[a]pyrene decreases expressionISOVWA8 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of VWA8 mRNACTDPMID:21632981 and PMID:26238291
Vwa8Ratbenzo[b]fluoranthene increases expressionISOVwa8 (Mus musculus)6480464benzo(b)fluoranthene results in increased expression of VWA8 mRNACTDPMID:26377693
Vwa8Ratbisphenol A affects expressionEXP 6480464bisphenol A affects the expression of VWA8 mRNACTDPMID:25181051
Vwa8Ratbisphenol A decreases methylationISOVWA8 (Homo sapiens)6480464bisphenol A results in decreased methylation of VWA8 geneCTDPMID:31601247

1 to 20 of 81 rows

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8Ratcytoplasm is_active_inIBAMGI:1919008 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Vwa8Ratmitochondrion located_inISOVWA8 (Homo sapiens)1624291 PMID:30204880RGDPMID:30204880
Vwa8Ratmitochondrion located_inIEAUniProtKB:Q8CC88 and ensembl:ENSMUSP000000489251600115GO_REF:0000107EnsemblGO_REF:0000107
Vwa8Ratmitochondrion located_inIEAUniProtKB:A3KMH1 and ensembl:ENSP000003686121600115GO_REF:0000107EnsemblGO_REF:0000107
Vwa8Ratmitochondrion located_inISOVwa8 (Mus musculus)1624291 PMID:28414126RGDPMID:28414126
Vwa8Ratperoxisome located_inISOVWA8 (Homo sapiens) and UniProtKB:A3KMH1-21624291 PMID:30204880RGDPMID:30204880

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Vwa8RatATP binding enablesIEAInterPro:IPR0117041600115GO_REF:0000002InterProGO_REF:0000002
Vwa8RatATP hydrolysis activity enablesISOVwa8 (Mus musculus)1624291 PMID:28414126RGDPMID:28414126
Vwa8RatATP hydrolysis activity enablesIEAInterPro:IPR003593 and InterPro:IPR0117041600115GO_REF:0000002InterProGO_REF:0000002
Vwa8RatATP hydrolysis activity enablesIEAUniProtKB:Q8CC88 and ensembl:ENSMUSP000000489251600115GO_REF:0000107EnsemblGO_REF:0000107
Vwa8Ratprotein binding enablesISOVWA8 (Homo sapiens)1624291UniProtKB:O00628 more ...RGDPMID:30204880


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
PMID:12477932   PMID:14651853   PMID:28414126   PMID:30204880   PMID:31630795  



Vwa8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81560,661,764 - 60,985,971 (+)NCBIGRCr8
mRatBN7.21554,252,703 - 54,576,871 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.01561,158,510 - 61,467,462 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.01561,069,439 - 61,153,292 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01564,733,018 - 64,817,848 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.01565,106,678 - 65,131,504 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41559,993,882 - 60,364,838 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11559,950,242 - 60,379,537 (+)NCBI
Celera1553,842,678 - 54,161,011 (+)NCBICelera
Cytogenetic Map15q11-q12NCBI
VWA8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381341,566,835 - 41,961,109 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1341,566,835 - 41,961,120 (-)EnsemblGRCh38hg38GRCh38
GRCh371342,140,971 - 42,535,245 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361341,038,961 - 41,433,221 (-)NCBINCBI36Build 36hg18NCBI36
Celera1323,199,011 - 23,592,898 (-)NCBICelera
Cytogenetic Map13q14.11NCBI
HuRef1322,941,888 - 23,338,138 (-)NCBIHuRef
CHM1_11342,108,485 - 42,502,867 (-)NCBICHM1_1
T2T-CHM13v2.01340,785,956 - 41,180,365 (-)NCBIT2T-CHM13v2.0
Vwa8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391479,086,489 - 79,439,750 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1479,086,492 - 79,439,750 (+)EnsemblGRCm39 Ensembl
GRCm381478,849,058 - 79,202,310 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1478,849,052 - 79,202,310 (+)EnsemblGRCm38mm10GRCm38
MGSCv371479,248,985 - 79,602,117 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361477,503,772 - 77,936,465 (+)NCBIMGSCv36mm8
Celera1476,362,512 - 76,701,437 (+)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1441.9NCBI
Vwa8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555184,351,781 - 4,723,479 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555184,351,781 - 4,723,479 (+)NCBIChiLan1.0ChiLan1.0
VWA8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21441,065,135 - 41,458,200 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11332,168,718 - 32,561,732 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01322,750,083 - 23,142,860 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11341,339,379 - 41,729,689 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1341,339,379 - 41,729,661 (-)Ensemblpanpan1.1panPan2
VWA8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1228,799,044 - 9,153,627 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl228,798,090 - 9,149,296 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha228,793,300 - 9,146,711 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0229,025,235 - 9,379,824 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl229,039,291 - 9,376,614 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1228,717,913 - 9,072,245 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0228,768,009 - 9,122,199 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0228,780,057 - 9,133,927 (+)NCBIUU_Cfam_GSD_1.0
LOC101965792
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945151,964,945 - 152,276,047 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367471,797,136 - 2,064,072 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367471,798,200 - 2,018,722 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VWA8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1125,064,771 - 25,457,134 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11125,064,780 - 25,455,287 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21125,821,408 - 26,011,445 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VWA8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1319,767,190 - 20,148,027 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl319,866,921 - 20,147,976 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605724,064,072 - 24,448,338 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vwa8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474813,159,518 - 13,631,333 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474813,159,660 - 13,630,727 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Vwa8
1996 total Variants

Predicted Target Of
Summary Value
Count of predictions:152
Count of miRNA genes:117
Interacting mature miRNAs:133
Transcripts:ENSRNOT00000013780, ENSRNOT00000070840, ENSRNOT00000074956
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat

1 to 10 of 25 rows
D15Got65  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,422,038 - 54,422,145 (+)MAPPERmRatBN7.2
Rnor_6.01561,307,664 - 61,307,770NCBIRnor6.0
Rnor_5.01564,972,305 - 64,972,411UniSTSRnor5.0
RGSC_v3.41560,163,434 - 60,163,540RGDRGSC3.4
RGSC_v3.41560,163,435 - 60,163,541UniSTSRGSC3.4
RGSC_v3.11560,179,214 - 60,179,320RGD
Celera1554,011,730 - 54,011,836UniSTS
RH 3.4 Map15452.3RGD
RH 3.4 Map15452.3UniSTS
Cytogenetic Map15q11-q12UniSTS
RH129773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,453,388 - 54,453,540 (+)MAPPERmRatBN7.2
Rnor_6.01561,344,209 - 61,344,360NCBIRnor6.0
Rnor_5.01565,009,677 - 65,009,828UniSTSRnor5.0
RGSC_v3.41560,201,235 - 60,201,386UniSTSRGSC3.4
Celera1554,038,235 - 54,038,386UniSTS
RH 3.4 Map15458.0UniSTS
Cytogenetic Map15q11-q12UniSTS
RH143518  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,414,064 - 54,414,339 (+)MAPPERmRatBN7.2
Rnor_6.01561,299,691 - 61,299,965NCBIRnor6.0
Rnor_5.01564,964,332 - 64,964,606UniSTSRnor5.0
RGSC_v3.41560,155,584 - 60,155,858UniSTSRGSC3.4
Celera1554,003,757 - 54,004,031UniSTS
RH 3.4 Map15458.3UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11-q12UniSTS
Cytogenetic Map15q11UniSTS
RH134704  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81560,985,648 - 60,985,920 (+)Marker Load Pipeline
mRatBN7.21554,576,552 - 54,576,824 (+)MAPPERmRatBN7.2
Rnor_6.01561,467,144 - 61,467,415NCBIRnor6.0
Rnor_5.01565,131,186 - 65,131,457UniSTSRnor5.0
RGSC_v3.41560,364,520 - 60,364,791UniSTSRGSC3.4
Celera1554,160,702 - 54,160,964UniSTS
RH 3.4 Map4685.32UniSTS
Cytogenetic Map15q11-q12UniSTS
Hars  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,415,320 - 54,415,449 (+)MAPPERmRatBN7.2
mRatBN7.21828,382,080 - 28,382,413 (+)MAPPERmRatBN7.2
Rnor_6.01829,611,977 - 29,612,309NCBIRnor6.0
Rnor_6.01561,300,947 - 61,301,075NCBIRnor6.0
Rnor_5.01829,315,784 - 29,316,116UniSTSRnor5.0
Rnor_5.01564,965,588 - 64,965,716UniSTSRnor5.0
RGSC_v3.41829,468,080 - 29,468,412UniSTSRGSC3.4
RGSC_v3.41560,156,840 - 60,156,968UniSTSRGSC3.4
Celera1554,005,013 - 54,005,141UniSTS
Celera1828,102,633 - 28,102,965UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11UniSTS
Cytogenetic Map15q11-q12UniSTS
RH130568  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21828,381,729 - 28,381,937 (+)MAPPERmRatBN7.2
mRatBN7.21554,415,592 - 54,415,947 (+)MAPPERmRatBN7.2
Rnor_6.01561,301,219 - 61,301,573NCBIRnor6.0
Rnor_6.01829,611,626 - 29,611,833NCBIRnor6.0
Rnor_5.01829,315,433 - 29,315,640UniSTSRnor5.0
Rnor_5.01564,965,860 - 64,966,214UniSTSRnor5.0
RGSC_v3.41560,157,112 - 60,157,466UniSTSRGSC3.4
RGSC_v3.41829,467,729 - 29,467,936UniSTSRGSC3.4
Celera1828,102,282 - 28,102,489UniSTS
Celera1554,005,285 - 54,005,639UniSTS
RH 3.4 Map18417.7UniSTS
Cytogenetic Map18p11UniSTS
Cytogenetic Map15q11-q12UniSTS
Cytogenetic Map15q11UniSTS
AU048166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,324,429 - 54,324,627 (+)MAPPERmRatBN7.2
Rnor_6.01561,207,680 - 61,207,877NCBIRnor6.0
Rnor_6.01561,141,190 - 61,141,387NCBIRnor6.0
Rnor_5.01564,806,460 - 64,806,657UniSTSRnor5.0
Rnor_5.01564,872,950 - 64,873,147UniSTSRnor5.0
RGSC_v3.41560,065,439 - 60,065,636UniSTSRGSC3.4
Celera1553,914,382 - 53,914,579UniSTS
Cytogenetic Map15q11-q12UniSTS
BF390452  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,254,161 - 54,254,316 (+)MAPPERmRatBN7.2
Rnor_6.01561,070,877 - 61,071,031NCBIRnor6.0
Rnor_5.01564,736,147 - 64,736,301UniSTSRnor5.0
RGSC_v3.41559,995,178 - 59,995,332UniSTSRGSC3.4
Celera1553,844,124 - 53,844,278UniSTS
RH 3.4 Map15458.7UniSTS
Cytogenetic Map15q11-q12UniSTS
AW535983  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21554,314,352 - 54,314,502 (+)MAPPERmRatBN7.2
Rnor_6.01561,197,603 - 61,197,752NCBIRnor6.0
Rnor_6.01561,131,113 - 61,131,262NCBIRnor6.0
Rnor_5.01564,862,873 - 64,863,022UniSTSRnor5.0
Rnor_5.01564,796,383 - 64,796,532UniSTSRnor5.0
RGSC_v3.41560,055,362 - 60,055,511UniSTSRGSC3.4
Celera1553,904,305 - 53,904,454UniSTS
RH 3.4 Map15456.4UniSTS
Cytogenetic Map15q11-q12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000084333   ⟹   ENSRNOP00000072799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1554,252,584 - 54,576,870 (+)Ensembl
Rnor_6.0 Ensembl1561,069,581 - 61,152,506 (+)Ensembl
RefSeq Acc Id: NM_001427283   ⟹   NP_001414212
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,661,877 - 60,985,971 (+)NCBI
RefSeq Acc Id: XM_039094044   ⟹   XP_038949972
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,681,484 - 60,985,954 (+)NCBI
mRatBN7.21554,253,008 - 54,576,871 (+)NCBI
RefSeq Acc Id: XM_039094045   ⟹   XP_038949973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,789,178 - 60,985,954 (+)NCBI
mRatBN7.21554,380,080 - 54,576,871 (+)NCBI
RefSeq Acc Id: XM_063274157   ⟹   XP_063130227
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,661,764 - 60,985,954 (+)NCBI
RefSeq Acc Id: XM_063274158   ⟹   XP_063130228
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81560,851,713 - 60,985,954 (+)NCBI
1 to 9 of 9 rows
Protein RefSeqs NP_001414212 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949972 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949973 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130227 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130228 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDM02345 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072799
  ENSRNOP00000072799.2
  ENSRNOP00000104923
1 to 9 of 9 rows
Ensembl Acc Id: ENSRNOP00000072799   ⟸   ENSRNOT00000084333
RefSeq Acc Id: XP_038949972   ⟸   XM_039094044
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949973   ⟸   XM_039094045
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063130227   ⟸   XM_063274157
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001414212   ⟸   NM_001427283
- UniProtKB: A0A0G2K3W1 (UniProtKB/TrEMBL)
VWFA

Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K3W1-F1-model_v2 AlphaFold A0A0G2K3W1 1-481 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699846
Promoter ID:EPDNEW_R10367
Type:initiation region
Name:Vwa8_1
Description:von Willebrand factor A domain containing 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01561,069,486 - 61,069,546EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-13006 BioCyc
Ensembl Genes ENSRNOG00000053145 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000084333 ENTREZGENE
  ENSRNOT00000084333.2 UniProtKB/TrEMBL
  ENSRNOT00000170597 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
  3.40.50.410 UniProtKB/TrEMBL
InterPro AAA+_ATPase UniProtKB/TrEMBL
  ATPase_dyneun-rel_AAA UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  VWA8 UniProtKB/TrEMBL
  VWF_A UniProtKB/TrEMBL
  vWFA_dom_sf UniProtKB/TrEMBL
NCBI Gene 290381 ENTREZGENE
PANTHER PTHR21610 UniProtKB/TrEMBL
  VON WILLEBRAND FACTOR A DOMAIN-CONTAINING PROTEIN 8 UniProtKB/TrEMBL
Pfam AAA_5 UniProtKB/TrEMBL
PhenoGen Vwa8 PhenoGen
PROSITE VWFA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053145 RatGTEx
SMART AAA UniProtKB/TrEMBL
  VWA UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF53300 UniProtKB/TrEMBL
UniProt A0A0G2K3W1 ENTREZGENE, UniProtKB/TrEMBL
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-10 Vwa8  von Willebrand factor A domain containing 8  RGD1308772  similar to KIAA0564 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1308772  similar to KIAA0564 protein   RGD1308772_predicted  similar to KIAA0564 protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308772_predicted  similar to KIAA0564 protein (predicted)  LOC290381_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC290381_predicted  similar to KIAA0564 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL