Aurkc (aurora kinase C) - Rat Genome Database

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Gene: Aurkc (aurora kinase C) Rattus norvegicus
Analyze
Symbol: Aurkc
Name: aurora kinase C
RGD ID: 1309573
Description: Predicted to enable histone serine kinase activity. Predicted to be involved in mitotic spindle organization; protein phosphorylation; and regulation of cytokinesis. Predicted to act upstream of or within protein autophosphorylation. Predicted to be located in chromosome; meiotic spindle midzone; and midbody. Predicted to be part of chromosome passenger complex. Predicted to be active in spindle microtubule; spindle midzone; and spindle pole centrosome. Human ortholog(s) of this gene implicated in spermatogenic failure 5. Orthologous to human AURKC (aurora kinase C); INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC103691033; LOC292554; serine/threonine-protein kinase 13; zinc finger protein 264-like; zinc finger protein 805-like
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2166,843,653 - 66,864,348 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl166,843,653 - 66,864,386 (-)Ensembl
Rnor_6.0169,958,452 - 69,964,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,958,452 - 69,963,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,352,903 - 71,372,735 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,242,016 - 65,244,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1165,320,200 - 65,340,826 (-)NCBI
Celera164,597,254 - 64,603,374 (-)NCBICelera
Cytogenetic Map1q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9809744   PMID:12584241   PMID:15670791   PMID:19116339   PMID:21558374  


Genomics

Comparative Map Data
Aurkc
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2166,843,653 - 66,864,348 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl166,843,653 - 66,864,386 (-)Ensembl
Rnor_6.0169,958,452 - 69,964,546 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl169,958,452 - 69,963,592 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,352,903 - 71,372,735 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4165,242,016 - 65,244,450 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1165,320,200 - 65,340,826 (-)NCBI
Celera164,597,254 - 64,603,374 (-)NCBICelera
Cytogenetic Map1q12NCBI
AURKC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381957,231,023 - 57,235,548 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1957,231,009 - 57,235,548 (+)EnsemblGRCh38hg38GRCh38
GRCh371957,742,391 - 57,746,916 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361962,434,189 - 62,438,728 (+)NCBINCBI36hg18NCBI36
Build 341962,433,981 - 62,438,727NCBI
Celera1954,785,675 - 54,790,201 (+)NCBI
Cytogenetic Map19q13.43NCBI
HuRef1954,054,719 - 54,059,120 (+)NCBIHuRef
CHM1_11957,735,964 - 57,740,487 (+)NCBICHM1_1
T2T-CHM13v2.01960,327,568 - 60,332,080 (+)NCBI
Aurkc
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3976,998,346 - 7,006,090 (+)NCBIGRCm39mm39
GRCm39 Ensembl76,998,299 - 7,006,090 (+)Ensembl
GRCm3876,995,347 - 7,003,091 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl76,995,300 - 7,003,091 (+)EnsemblGRCm38mm10GRCm38
MGSCv3776,948,096 - 6,955,802 (+)NCBIGRCm37mm9NCBIm37
MGSCv3676,599,386 - 6,607,177 (+)NCBImm8
Celera76,720,780 - 6,728,614 (+)NCBICelera
Cytogenetic Map7A1NCBI
cM Map74.06NCBI
AURKC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11963,080,977 - 63,086,030 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1963,081,342 - 63,086,030 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01954,246,446 - 54,251,734 (+)NCBIMhudiblu_PPA_v0panPan3
AURKC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11100,834,016 - 100,837,657 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1100,834,115 - 100,837,329 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.01101,480,455 - 101,484,094 (-)NCBI
ROS_Cfam_1.0 Ensembl1101,480,550 - 101,483,959 (-)Ensembl
UMICH_Zoey_3.11101,149,475 - 101,153,108 (-)NCBI
UNSW_CanFamBas_1.01100,835,827 - 100,839,459 (-)NCBI
UU_Cfam_GSD_1.01101,592,105 - 101,595,738 (-)NCBI
LOC101972657
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093492,952,865 - 2,956,209 (-)NCBI
SpeTri2.0NW_00493705514,992 - 17,802 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AURKC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1661,584,575 - 61,588,402 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
AURKC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1649,633,395 - 49,638,637 (+)NCBIChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660452,718,097 - 2,723,514 (+)NCBIVero_WHO_p1.0
Aurkc
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248321,088,996 - 1,094,827 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248321,090,060 - 1,094,814 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH134057  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0169,958,676 - 69,959,220NCBIRnor6.0
Rnor_5.0171,353,127 - 71,353,671UniSTSRnor5.0
RGSC_v3.4165,242,239 - 65,242,824UniSTSRGSC3.4
Celera164,597,478 - 64,598,047UniSTS
RH 3.4 Map1740.6UniSTS
Cytogenetic Map1q12UniSTS
RH134138  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2166,850,793 - 66,850,991 (+)MAPPERmRatBN7.2
Rnor_6.0169,965,565 - 69,965,762NCBIRnor6.0
Celera164,604,393 - 64,604,591UniSTS
RH 3.4 Map1746.4UniSTS
Cytogenetic Map1q12UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:19
Count of miRNA genes:19
Interacting mature miRNAs:19
Transcripts:ENSRNOT00000021245
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 28 4 4 1 4 66 22 37 4
Low 1 15 53 37 18 37 8 11 8 13 4 7 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001308536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017588886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103781 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103803 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021245   ⟹   ENSRNOP00000021248
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,843,672 - 66,864,386 (-)Ensembl
Rnor_6.0 Ensembl169,958,452 - 69,963,592 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119286   ⟹   ENSRNOP00000088690
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,843,653 - 66,849,775 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119494   ⟹   ENSRNOP00000078675
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl166,843,672 - 66,864,386 (-)Ensembl
RefSeq Acc Id: NM_001308536   ⟹   NP_001295465
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,849,775 (-)NCBI
Rnor_6.0169,958,452 - 69,964,546 (-)NCBI
Celera164,597,254 - 64,603,374 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017588885   ⟹   XP_017444374
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,849,663 (-)NCBI
Rnor_6.0169,958,452 - 69,964,499 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039103776   ⟹   XP_038959704
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103780   ⟹   XP_038959708
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103781   ⟹   XP_038959709
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103782   ⟹   XP_038959710
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103786   ⟹   XP_038959714
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103787   ⟹   XP_038959715
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,859,842 (-)NCBI
RefSeq Acc Id: XM_039103789   ⟹   XP_038959717
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,348 (-)NCBI
RefSeq Acc Id: XM_039103790   ⟹   XP_038959718
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103791   ⟹   XP_038959719
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103795   ⟹   XP_038959723
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103797   ⟹   XP_038959725
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,348 (-)NCBI
RefSeq Acc Id: XM_039103799   ⟹   XP_038959727
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,348 (-)NCBI
RefSeq Acc Id: XM_039103803   ⟹   XP_038959731
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,849,304 (-)NCBI
RefSeq Acc Id: XM_039103806   ⟹   XP_038959734
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,658 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103810   ⟹   XP_038959738
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,845,988 - 66,864,346 (-)NCBI
RefSeq Acc Id: XM_039103814   ⟹   XP_038959742
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2166,843,653 - 66,864,346 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001295465   ⟸   NM_001308536
- Sequence:
RefSeq Acc Id: XP_017444374   ⟸   XM_017588885
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000021248   ⟸   ENSRNOT00000021245
RefSeq Acc Id: XP_038959727   ⟸   XM_039103799
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959717   ⟸   XM_039103789
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959725   ⟸   XM_039103797
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959704   ⟸   XM_039103776
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038959723   ⟸   XM_039103795
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959710   ⟸   XM_039103782
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959718   ⟸   XM_039103790
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959719   ⟸   XM_039103791
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959708   ⟸   XM_039103780
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959742   ⟸   XM_039103814
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038959709   ⟸   XM_039103781
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959714   ⟸   XM_039103786
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959715   ⟸   XM_039103787
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959731   ⟸   XM_039103803
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959734   ⟸   XM_039103806
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038959738   ⟸   XM_039103810
- Peptide Label: isoform X4
RefSeq Acc Id: ENSRNOP00000078675   ⟸   ENSRNOT00000119494
RefSeq Acc Id: ENSRNOP00000088690   ⟸   ENSRNOT00000119286

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AD76-F1-model_v2 AlphaFold D4AD76 1-308 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309573 AgrOrtholog
BioCyc Gene G2FUF-60955 BioCyc
Ensembl Genes ENSRNOG00000015825 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021248 ENTREZGENE
  ENSRNOP00000021248.7 UniProtKB/TrEMBL
  ENSRNOP00000078675 ENTREZGENE
  ENSRNOP00000078675.1 UniProtKB/TrEMBL
  ENSRNOP00000088690 ENTREZGENE
  ENSRNOP00000088690.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021245 ENTREZGENE
  ENSRNOT00000021245.8 UniProtKB/TrEMBL
  ENSRNOT00000119286 ENTREZGENE
  ENSRNOT00000119286.1 UniProtKB/TrEMBL
  ENSRNOT00000119494 ENTREZGENE
  ENSRNOT00000119494.1 UniProtKB/TrEMBL
InterPro Aur UniProtKB/TrEMBL
  AURKC UniProtKB/TrEMBL
  Kinase-like_dom UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 292554 ENTREZGENE
PANTHER PTHR24350 UniProtKB/TrEMBL
  PTHR24350:SF3 UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PhenoGen Aurkc PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt A0A8I6G3L3_RAT UniProtKB/TrEMBL
  A0A8I6GHC0_RAT UniProtKB/TrEMBL
  D4AD76_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Aurkc  aurora kinase C  LOC103691033  zinc finger protein 805-like  Data Merged 737654 PROVISIONAL
2014-08-25 LOC103691033  zinc finger protein 805-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 Aurkc  aurora kinase C   Aurkc_predicted  aurora kinase C (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Aurkc_predicted  aurora kinase C (predicted)      Symbol and Name status set to approved 70820 APPROVED