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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Vps4b | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of VPS4B mRNA | CTD | PMID:22206623 | Vps4b | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VPS4B mRNA | CTD | PMID:22206623 | Vps4b | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Vps4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of VPS4B mRNA | CTD | PMID:19770486 | Vps4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of VPS4B mRNA | CTD | PMID:33387578 | Vps4b | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of VPS4B mRNA | CTD | PMID:32109520 | Vps4b | Rat | 2,6-dimethoxyphenol | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization of VPS4B protein | CTD | PMID:38598786 | Vps4b | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of VPS4B mRNA | CTD | PMID:21346803 | Vps4b | Rat | 3,3',5,5'-tetrabromobisphenol A | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | tetrabromobisphenol A results in decreased expression of VPS4B protein | CTD | PMID:31675489 | Vps4b | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of VPS4B protein | CTD | PMID:34915118 | Vps4b | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VPS4B mRNA | CTD | PMID:28628672 | Vps4b | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of VPS4B mRNA | CTD | PMID:18648102 | Vps4b | Rat | acrylamide | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Acrylamide results in increased expression of VPS4B mRNA | CTD | PMID:32763439 | Vps4b | Rat | Aroclor 1254 | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of VPS4B mRNA | CTD | PMID:23650126 | Vps4b | Rat | atrazine | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Atrazine results in decreased expression of VPS4B mRNA | CTD | PMID:22378314 | Vps4b | Rat | benzo[a]pyrene | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of VPS4B mRNA | CTD | PMID:22228805 | Vps4b | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | Vps4b | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Vps4b | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of VPS4B mRNA | CTD | PMID:25181051 | Vps4b | Rat | bisphenol A | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | bisphenol A results in increased expression of VPS4B protein | CTD | PMID:34186270 | Vps4b | Rat | bisphenol A | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of VPS4B protein | CTD | PMID:31675489 | Vps4b | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of VPS4B mRNA | CTD | PMID:34947998 | Vps4b | Rat | bisphenol A | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VPS4B mRNA | CTD | PMID:28628672 | Vps4b | Rat | bisphenol AF | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | bisphenol AF results in increased expression of VPS4B protein | CTD | PMID:34186270 | Vps4b | Rat | cadmium atom | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VPS4B mRNA | CTD | PMID:37325564 | Vps4b | Rat | cadmium dichloride | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VPS4B mRNA | CTD | PMID:37325564 | Vps4b | Rat | CGP 52608 | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to VPS4B gene] | CTD | PMID:28238834 | Vps4b | Rat | cobalt dichloride | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of VPS4B mRNA | CTD | PMID:19376846 | Vps4b | Rat | copper(II) sulfate | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of VPS4B mRNA | CTD | PMID:19549813 | Vps4b | Rat | coumarin | decreases phosphorylation | ISO | VPS4B (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of VPS4B protein | CTD | PMID:35688186 | Vps4b | Rat | cyclosporin A | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Cyclosporine results in increased expression of VPS4B mRNA | CTD | PMID:19770486 | Vps4b | Rat | decabromodiphenyl ether | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | decabromobiphenyl ether results in decreased expression of VPS4B protein | CTD | PMID:31675489 | Vps4b | Rat | dexamethasone | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VPS4B mRNA | CTD | PMID:28628672 | Vps4b | Rat | dicrotophos | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of VPS4B mRNA | CTD | PMID:28302478 | Vps4b | Rat | doxorubicin | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of VPS4B mRNA | CTD | PMID:29803840 | Vps4b | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of VPS4B mRNA | CTD | PMID:24136188 and PMID:24793618 | Vps4b | Rat | folic acid | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of VPS4B mRNA | CTD | PMID:22206623 | Vps4b | Rat | folic acid | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | Folic Acid results in decreased expression of VPS4B mRNA | CTD | PMID:25629700 | Vps4b | Rat | formaldehyde | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of VPS4B mRNA | CTD | PMID:23649840 | Vps4b | Rat | FR900359 | increases phosphorylation | ISO | VPS4B (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of VPS4B protein | CTD | PMID:37730182 | Vps4b | Rat | furfural | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [pyrogallol 1 and 3-dimethyl ether co-treated with Furaldehyde] results in decreased expression of and affects the localization of VPS4B protein | CTD | PMID:38598786 | Vps4b | Rat | genistein | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | Genistein results in decreased expression of VPS4B mRNA | CTD | PMID:32186404 | Vps4b | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of VPS4B mRNA | CTD | PMID:22061828 | Vps4b | Rat | indometacin | multiple interactions | ISO | VPS4B (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of VPS4B mRNA | CTD | PMID:28628672 | Vps4b | Rat | ivermectin | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of VPS4B protein | CTD | PMID:32959892 | Vps4b | Rat | lamivudine | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA | CTD | PMID:16931933 | Vps4b | Rat | leflunomide | decreases expression | ISO | VPS4B (Homo sapiens) | 6480464 | leflunomide results in decreased expression of VPS4B mRNA | CTD | PMID:28988120 | Vps4b | Rat | methyl methanesulfonate | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of VPS4B mRNA | CTD | PMID:23649840 | Vps4b | Rat | N-methyl-4-phenylpyridinium | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of VPS4B protein | CTD | PMID:26558463 | Vps4b | Rat | paracetamol | affects expression | ISO | Vps4b (Mus musculus) | 6480464 | Acetaminophen affects the expression of VPS4B mRNA | CTD | PMID:17562736 | Vps4b | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of VPS4B mRNA | CTD | PMID:33387578 | Vps4b | Rat | serpentine asbestos | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Asbestos and Serpentine results in increased expression of VPS4B | CTD | PMID:19105532 | Vps4b | Rat | sodium arsenite | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of VPS4B mRNA | CTD | PMID:38568856 | Vps4b | Rat | sodium fluoride | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of VPS4B protein | CTD | PMID:28918527 | Vps4b | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of VPS4B mRNA | CTD | PMID:19281266 | Vps4b | Rat | tetrachloromethane | increases expression | ISO | Vps4b (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of VPS4B mRNA | CTD | PMID:31919559 | Vps4b | Rat | triptonide | decreases expression | ISO | Vps4b (Mus musculus) | 6480464 | triptonide results in decreased expression of VPS4B mRNA | CTD | PMID:33045310 | Vps4b | Rat | urethane | increases expression | ISO | VPS4B (Homo sapiens) | 6480464 | Urethane results in increased expression of VPS4B mRNA | CTD | PMID:28818685 | Vps4b | Rat | zidovudine | multiple interactions | ISO | Vps4b (Mus musculus) | 6480464 | [Zidovudine co-treated with Lamivudine] results in decreased expression of VPS4B mRNA | CTD | PMID:16931933 | |