Vps4b (vacuolar protein sorting 4 homolog B) - Rat Genome Database

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Gene: Vps4b (vacuolar protein sorting 4 homolog B) Rattus norvegicus
Analyze
Symbol: Vps4b
Name: vacuolar protein sorting 4 homolog B
RGD ID: 1305969
Description: Predicted to enable ATP hydrolysis activity and protein homodimerization activity. Predicted to be involved in several processes, including proteolysis involved in protein catabolic process; regulation of cell cycle process; and regulation of exosomal secretion. Predicted to act upstream of or within several processes, including endosome organization; establishment of blood-brain barrier; and potassium ion transport. Predicted to be located in several cellular components, including Flemming body; endosome membrane; and microtubule cytoskeleton. Orthologous to human VPS4B (vacuolar protein sorting 4 homolog B); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC360834; MGC116271; vacuolar protein sorting 4 homolog B (S. cerevisiae); vacuolar protein sorting 4b; vacuolar protein sorting 4b (yeast); vacuolar protein sorting-associated protein 4B
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21322,907,105 - 22,932,200 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,907,109 - 22,932,229 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,229,947 - 23,255,030 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,514,416 - 24,539,500 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,200,133 - 23,225,220 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,825,261 - 26,850,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,825,261 - 26,850,460 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,975,737 - 32,000,936 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,959,843 - 12,984,933 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11312,959,842 - 12,984,933 (-)NCBI
Celera1322,765,509 - 22,790,596 (-)NCBICelera
Cytogenetic Map13p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:8082782   PMID:10637304   PMID:11563910   PMID:12477932   PMID:14505570   PMID:15024011   PMID:15173323   PMID:16193069   PMID:16757520   PMID:17928862   PMID:17940959   PMID:18687924  
PMID:19056867   PMID:20616062   PMID:21238931   PMID:22547407   PMID:22660413   PMID:23376485   PMID:23533145   PMID:24077878   PMID:24105262   PMID:24107264  


Genomics

Comparative Map Data
Vps4b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21322,907,105 - 22,932,200 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1322,907,109 - 22,932,229 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1323,229,947 - 23,255,030 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01324,514,416 - 24,539,500 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01323,200,133 - 23,225,220 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01326,825,261 - 26,850,460 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1326,825,261 - 26,850,460 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01331,975,737 - 32,000,936 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41312,959,843 - 12,984,933 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11312,959,842 - 12,984,933 (-)NCBI
Celera1322,765,509 - 22,790,596 (-)NCBICelera
Cytogenetic Map13p11NCBI
VPS4B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381863,389,190 - 63,422,476 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1863,389,190 - 63,422,483 (-)EnsemblGRCh38hg38GRCh38
GRCh371861,056,423 - 61,089,709 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361859,207,403 - 59,240,732 (-)NCBINCBI36Build 36hg18NCBI36
Build 341859,207,406 - 59,240,673NCBI
Celera1857,776,059 - 57,809,388 (-)NCBICelera
Cytogenetic Map18q21.33NCBI
HuRef1857,754,990 - 57,788,280 (-)NCBIHuRef
CHM1_11861,052,390 - 61,085,722 (-)NCBICHM1_1
T2T-CHM13v2.01863,594,233 - 63,627,515 (-)NCBIT2T-CHM13v2.0
Vps4b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391106,698,518 - 106,724,455 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1106,691,801 - 106,724,458 (-)EnsemblGRCm39 Ensembl
GRCm381106,770,788 - 106,796,725 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1106,764,071 - 106,796,728 (-)EnsemblGRCm38mm10GRCm38
MGSCv371108,667,365 - 108,693,302 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361108,598,705 - 108,624,223 (-)NCBIMGSCv36mm8
Celera1109,620,154 - 109,646,158 (-)NCBICelera
Cytogenetic Map1E2.1NCBI
cM Map150.1NCBI
Vps4b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540247,154,007 - 47,184,021 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540247,154,350 - 47,183,979 (-)NCBIChiLan1.0ChiLan1.0
VPS4B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan11866,593,051 - 66,626,392 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01856,749,439 - 56,782,660 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11860,062,080 - 60,095,109 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1860,060,285 - 60,095,109 (-)Ensemblpanpan1.1panPan2
VPS4B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1113,638,965 - 13,673,295 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl113,639,004 - 13,669,072 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha114,605,156 - 14,639,495 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0113,500,614 - 13,534,990 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl113,500,669 - 13,534,959 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1113,538,762 - 13,573,109 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0113,468,029 - 13,502,377 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0113,716,838 - 13,751,163 (+)NCBIUU_Cfam_GSD_1.0
Vps4b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494426,887,096 - 26,922,486 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364972,126,061 - 2,161,485 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364972,126,064 - 2,161,451 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
VPS4B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1158,233,070 - 158,270,679 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11158,233,039 - 158,273,533 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21175,754,073 - 175,760,220 (+)NCBISscrofa10.2Sscrofa10.2susScr3
VPS4B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11816,336,959 - 16,370,208 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1816,336,921 - 16,370,291 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660609,317,729 - 9,350,925 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Vps4b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247929,098,291 - 9,128,931 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Vps4b
139 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:406
Count of miRNA genes:251
Interacting mature miRNAs:286
Transcripts:ENSRNOT00000003715
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317027Aia22Adjuvant induced arthritis QTL 222.29joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)13134266636Rat
738036Lnnr4Liver neoplastic nodule remodeling QTL 43.64liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)13142356786Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131101056920Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131101056920Rat
631672Iddm12Insulin dependent diabetes mellitus QTL 122.20.0032blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)13599466834535351Rat
61339Bp24Blood pressure QTL 240.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13599466844807491Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13599483377046787Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)138897350101631289Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)13931346554313465Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)13931346554313465Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)13983154154831541Rat
2303031Bp326Blood pressure QTL 326arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131176653523001904Rat
2317034Aia9Adjuvant induced arthritis QTL 94.62joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131176653532331607Rat
2317044Aia23Adjuvant induced arthritis QTL 232.3joint integrity trait (VT:0010548)ankle joint diameter (CMO:0002148)131176653532331607Rat
1300163Cardf1Cardiac cell morphology QTL 14.18aorta morphology trait (VT:0000272)artery lesion measurement (CMO:0000975)131192944945417941Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131192944946193066Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131491565559915655Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)131515872260158722Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131769443653050594Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1320605871101339738Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132230187567301875Rat

Markers in Region
RH140013  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21322,907,130 - 22,907,348 (+)MAPPERmRatBN7.2
mRatBN7.22010,280,315 - 10,280,533 (+)MAPPERmRatBN7.2
Rnor_6.02011,001,431 - 11,001,648NCBIRnor6.0
Rnor_6.01326,825,287 - 26,825,504NCBIRnor6.0
Rnor_5.02013,172,334 - 13,172,551UniSTSRnor5.0
Rnor_5.01331,975,763 - 31,975,980UniSTSRnor5.0
RGSC_v3.42010,615,304 - 10,615,521UniSTSRGSC3.4
RGSC_v3.41312,959,869 - 12,960,086UniSTSRGSC3.4
Celera1322,765,535 - 22,765,752UniSTS
Celera2011,789,654 - 11,789,871UniSTS
Cytogenetic Map13p13UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 10 74 35 38 11 8
Low 1 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000003715   ⟹   ENSRNOP00000003715
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,907,109 - 22,932,229 (-)Ensembl
Rnor_6.0 Ensembl1326,825,261 - 26,850,460 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105495   ⟹   ENSRNOP00000089387
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1322,907,224 - 22,931,985 (-)Ensembl
RefSeq Acc Id: NM_001025716   ⟹   NP_001020887
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21322,907,105 - 22,932,200 (-)NCBI
Rnor_6.01326,825,261 - 26,850,460 (-)NCBI
Rnor_5.01331,975,737 - 32,000,936 (-)NCBI
RGSC_v3.41312,959,843 - 12,984,933 (-)RGD
Celera1322,765,509 - 22,790,596 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001020887 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH99128 (Get FASTA)   NCBI Sequence Viewer  
  EDL91749 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000003715
  ENSRNOP00000003715.4
  ENSRNOP00000089387.1
RefSeq Acc Id: NP_001020887   ⟸   NM_001025716
- UniProtKB: Q4KLL7 (UniProtKB/TrEMBL),   A0A8I6GH80 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000003715   ⟸   ENSRNOT00000003715
RefSeq Acc Id: ENSRNOP00000089387   ⟸   ENSRNOT00000105495
Protein Domains
AAA+ ATPase   MIT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KLL7-F1-model_v2 AlphaFold Q4KLL7 1-444 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698751
Promoter ID:EPDNEW_R9276
Type:initiation region
Name:Vps4b_1
Description:vacuolar protein sorting 4 homolog B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01326,850,483 - 26,850,543EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305969 AgrOrtholog
BioCyc Gene G2FUF-18601 BioCyc
Ensembl Genes ENSRNOG00000002705 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003715 ENTREZGENE
  ENSRNOT00000003715.5 UniProtKB/TrEMBL
  ENSRNOT00000105495.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
  Phosphotransferase system, lactose/cellobiose-type IIA subunit UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7459593 IMAGE-MGC_LOAD
InterPro AAA_lid_3 UniProtKB/TrEMBL
  ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  ATPase_AAA_CS UniProtKB/TrEMBL
  MIT UniProtKB/TrEMBL
  MIT_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
  VPS4_MIT UniProtKB/TrEMBL
KEGG Report rno:360834 UniProtKB/TrEMBL
MGC_CLONE MGC:116271 IMAGE-MGC_LOAD
NCBI Gene 360834 ENTREZGENE
PANTHER AAA DOMAIN-CONTAINING UniProtKB/TrEMBL
  PTHR23074:SF72 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  AAA_lid_3 UniProtKB/TrEMBL
  MIT UniProtKB/TrEMBL
  Vps4_C UniProtKB/TrEMBL
PhenoGen Vps4b PhenoGen
PROSITE AAA UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002705 RatGTEx
SMART AAA UniProtKB/TrEMBL
  MIT UniProtKB/TrEMBL
Superfamily-SCOP SSF116846 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A8I6GH80 ENTREZGENE, UniProtKB/TrEMBL
  F7EZ84_RAT UniProtKB/TrEMBL
  Q4KLL7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-13 Vps4b  vacuolar protein sorting 4 homolog B  Vps4b  vacuolar protein sorting 4 homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Vps4b  vacuolar protein sorting 4 homolog B (S. cerevisiae)  Vps4b  vacuolar protein sorting 4b (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Vps4b  vacuolar protein sorting 4b (yeast)  Vps4b_predicted  vacuolar protein sorting 4b (yeast) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Vps4b_predicted  vacuolar protein sorting 4b (yeast) (predicted)      Symbol and Name status set to approved 70820 APPROVED