Gene: Bcr (BCR, RhoGEF and GTPase activating protein) Rattus norvegicus
Symbol: Bcr
Name: BCR, RhoGEF and GTPase activating protein
Description: ENCODES a protein that exhibits enzyme binding; GTPase activator activity (ortholog); INVOLVED IN platelet-derived growth factor receptor signaling pathway; protein autophosphorylation; actin cytoskeleton organization (ortholog); PARTICIPATES IN chronic myeloid leukemia pathway; ASSOCIATED WITH Blast Crisis (ortholog); Leukemia (ortholog); Leukemia, Myelogenous, Chronic, BCR-ABL Positive (ortholog); FOUND IN cytoplasm; cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; bisphenol A; chlorpyrifos
Type: protein-coding
RefSeq Status: MODEL
Also known as: breakpoint cluster region; breakpoint cluster region homolog; LOC309696
Homo sapiens (human) : BCR (BCR, RhoGEF and GTPase activating protein)  HGNC  AGR
Mus musculus (house mouse) : Bcr (breakpoint cluster region)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Bcr (BCR, RhoGEF and GTPase activating protein)
Pan paniscus (bonobo/pygmy chimpanzee) : BCR (BCR, RhoGEF and GTPase activating protein)
Canis lupus familiaris (dog) : BCR (BCR, RhoGEF and GTPase activating protein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bcr (BCR, RhoGEF and GTPase activating protein)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02014,421,250 - 14,546,406 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02016,604,476 - 16,729,388 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42013,972,773 - 14,097,816 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12013,973,364 - 14,098,043 (-)NCBI
Celera2014,955,473 - 15,079,934 (-)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Bcr
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1307993
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE