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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:bleomycin A2
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Accession:CHEBI:3139 term browser browse the term
Definition:A bleomycin that has formula C55H84N17O21S3.
Synonyms:exact_synonym: (betaR)-N(alpha)-{[6-amino-2-((1S)-3-amino-1-{[(2S)-2,3-diamino-3-oxopropyl]amino}-3-oxopropyl)-5-methylpyrimidin-4-yl]carbonyl}-beta-{2-O-[3-O-(aminocarbonyl)-alpha-D-mannopyranosyl]-alpha-L-gulopyranosyloxy}-N-[(1R,2S,3S)-5-({(1S,2R)-1-[({2-[4-({[3-(dimethylsulfonio)propyl]amino}carbonyl)-2,4'-bi-1,3-thiazol-2'-yl]ethyl}amino)carbonyl]-2-hydroxypropyl}amino)-3-hydroxy-4-methyl-5-oxopentan-2-yl]-L-histidinamide
 related_synonym: Bleomycin;   Formula=C55H84N17O21S3;   InChI=1S/C55H83N17O21S3/c1-20-33(69-46(72-44(20)58)25(12-31(57)76)64-13-24(56)45(59)82)50(86)71-35(41(26-14-61-19-65-26)91-54-43(39(80)37(78)29(15-73)90-54)92-53-40(81)42(93-55(60)88)38(79)30(16-74)89-53)51(87)66-22(3)36(77)21(2)47(83)70-34(23(4)75)49(85)63-10-8-32-67-28(18-94-32)52-68-27(17-95-52)48(84)62-9-7-11-96(5)6/h14,17-19,21-25,29-30,34-43,53-54,64,73-75,77-81H,7-13,15-16,56H2,1-6H3,(H13-,57,58,59,60,61,62,63,65,66,69,70,71,72,76,82,83,84,85,86,87,88)/p+1/t21-,22+,23+,24-,25-,29-,30+,34-,35-,36-,37+,38+,39-,40-,41-,42-,43-,53+,54-/m0/s1;   InChIKey=OYVAGSVQBOHSSS-UAPAGMARSA-O;   N(1)-[3-(dimethylsulfonio)propyl]bleomycinamide;   SMILES=[H][C@](C)(NC(=O)[C@@]([H])(NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1c[nH]cn1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCc1nc(cs1)-c1nc(cs1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O
 alt_id: CHEBI:165316;   CHEBI:357107;   CHEBI:41102;   CHEBI:653800
 xref: Beilstein:4379083;   CAS:11056-06-7;   CAS:11116-31-7;   Gmelin:1667354;   KEGG:C06854;   KEGG:C15773;   KEGG:D07535;   KNApSAcK:C00018738
 xref_mesh: MESH:D001761
 xref: PDBeChem:BLM;   PMID:12477361;   Wikipedia:Bleomycin


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bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca3 ATP binding cassette subfamily A member 3 decreases expression EXP Bleomycin results in decreased expression of ABCA3 mRNA; Bleomycin results in decreased expression of ABCA3 protein CTD PMID:34425168 NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions
decreases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] CTD PMID:20581171 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions
decreases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977 		JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
Bleomycin results in decreased expression of ACTA2 protein
Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] 		CTD PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 More... NCBI chr 1:241,159,723...241,172,503
Ensembl chr 1:231,746,548...231,759,554 		JBrowse link
G Actg1 actin, gamma 1 increases expression ISO Bleomycin results in increased expression of ACTG1 mRNA CTD PMID:36087614 NCBI chr10:105,619,738...105,622,587
Ensembl chr10:105,619,737...105,624,232
Ensembl chr 3:105,619,737...105,624,232 		JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251 		JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847 		JBrowse link
G Actr10 actin related protein 10 increases expression ISO Bleomycin results in increased expression of ACTR10 mRNA CTD PMID:36087614 NCBI chr 6:89,446,141...89,472,350
Ensembl chr 6:89,446,093...89,473,047 		JBrowse link
G Actr3b actin related protein 3B increases expression ISO Bleomycin results in increased expression of ACTR3B mRNA CTD PMID:36087614 NCBI chr 4:9,261,631...9,355,496
Ensembl chr 4:9,262,233...9,355,441 		JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639 		JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919 		JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression 		EXP protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705 PMID:25933445 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression 		EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr11:78,121,388...78,127,998
Ensembl chr11:78,117,918...78,145,999 		JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]]; baicalein inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein]; Bleomycin affects the expression of and affects the localization of AIFM1 protein; Diazoxide inhibits the reaction [Bleomycin affects the expression of and affects the localization of AIFM1 protein] CTD PMID:37783230 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256 		JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 PMID:26520185 NCBI chr 6:137,534,810...137,555,131
Ensembl chr 6:131,713,720...131,733,921 		JBrowse link
G Alb albumin increases expression EXP Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961 		JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066 		JBrowse link
G Angptl3 angiopoietin-like 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ANGPTL3 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ANGPTL3 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ANGPTL3 protein] 		CTD PMID:30825431 NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957 		JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919 		JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054 		JBrowse link
G Anxa2 annexin A2 decreases expression EXP Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658 		JBrowse link
G Anxa3 annexin A3 decreases expression EXP Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617 		JBrowse link
G Anxa4 annexin A4 decreases expression EXP Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161 		JBrowse link
G Anxa5 annexin A5 increases expression EXP Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369 		JBrowse link
G Anxa6 annexin A6 decreases expression EXP Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433 		JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385 		JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 4:85,812,784...85,824,964
Ensembl chr 4:84,482,512...84,494,690 		JBrowse link
G Areg amphiregulin increases expression ISO Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535 		JBrowse link
G Arg1 arginase 1 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein
Bleomycin results in decreased expression of ARG1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ARG1 protein] 		CTD PMID:26345256 PMID:26526764 PMID:30825431 PMID:33647319 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422 		JBrowse link
G Atf4 activating transcription factor 4 multiple interactions
increases expression 		EXP pachymic acid inhibits the reaction [Bleomycin results in increased expression of ATF4 protein] CTD PMID:37163307 NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446 		JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation 		ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437 		JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273 		JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Bleomycin results in increased expression of ATP5IF1 protein CTD PMID:25933445 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668 		JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013 		JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Bleomycin results in decreased expression of ATP5PO protein CTD PMID:29733421 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression 		ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Bleomycin results in decreased expression of ATP6V1A protein 		CTD PMID:29733421 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215 		JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression 		EXP
ISO 		allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein]]; baicalein inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of BAX protein] 		CTD PMID:23656969 PMID:26093215 PMID:32278510 PMID:37783230 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
decreases expression 		EXP
ISO 		[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]]; baicalein inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]; Diazoxide inhibits the reaction [Bleomycin results in decreased expression of BCL2 protein] 		CTD PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 More... NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression 		ISO thymoquinone inhibits the reaction [Bleomycin results in decreased expression of BCL2L1 mRNA] CTD PMID:34818114 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974 		JBrowse link
G Bik BCL2-interacting killer increases expression ISO Bleomycin results in increased expression of BIK mRNA CTD PMID:36087614 NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296 		JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression 		ISO
EXP 		BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein 		CTD PMID:10815900 PMID:15371238 NCBI chr 8:13,253,697...13,273,672
Ensembl chr 8:4,968,842...4,988,732 		JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr10:103,567,369...103,580,069
Ensembl chr10:103,073,408...103,081,380 		JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212 		JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788 		JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:205,731,828...205,743,430
Ensembl chr 1:205,733,872...205,743,421 		JBrowse link
G C1qb complement C1q B chain increases expression ISO Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407 		JBrowse link
G Calca calcitonin-related polypeptide alpha increases expression ISO Bleomycin results in increased expression of CALCA mRNA CTD PMID:36087614 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105 		JBrowse link
G Cald1 caldesmon 1 increases expression EXP Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 4:63,265,781...63,446,938
Ensembl chr 4:63,265,942...63,446,932 		JBrowse link
G Calml3 calmodulin-like 3 decreases expression EXP Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175 		JBrowse link
G Calr calreticulin increases expression EXP Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414 		JBrowse link
G Calu calumenin increases expression EXP Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593 		JBrowse link
G Car1 carbonic anhydrase 1 decreases expression EXP Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208 		JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression EXP Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019 		JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
increases expression
increases cleavage 		EXP
ISO 		[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
Bleomycin results in increased activity of CASP3 protein
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein]]; baicalein inhibits the reaction [Bleomycin results in increased cleavage of CASP3 protein] 		CTD PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 More... NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
increases expression 		EXP
ISO 		Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein; pachymic acid inhibits the reaction [Bleomycin results in increased expression of CASP9 protein]
Bleomycin results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA 		CTD PMID:15371238 PMID:22687607 PMID:26800624 PMID:37163307 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cast calpastatin increases expression EXP Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr 2:5,707,633...5,817,213
Ensembl chr 2:3,973,112...4,082,659 		JBrowse link
G Cat catalase increases response to substance
multiple interactions
increases expression
decreases activity 		ISO
EXP 		CAT protein results in increased susceptibility to Bleomycin
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
Bleomycin results in increased expression of CAT protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein]; pachymic acid inhibits the reaction [Bleomycin results in decreased activity of CAT protein] 		CTD PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 More... NCBI chr 3:110,297,340...110,329,526
Ensembl chr 3:89,842,399...89,874,478 		JBrowse link
G Cav1 caveolin 1 decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of CAV1 protein
Bleomycin results in decreased expression of CAV1 mRNA; Bleomycin results in decreased expression of CAV1 protein
yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in decreased expression of CAV1 protein] 		CTD PMID:25933445 PMID:37898439 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression EXP Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147 		JBrowse link
G Cbx8 chromobox 8 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of CBX8 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA] 		CTD PMID:30825431 NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024 		JBrowse link
G Cckar cholecystokinin A receptor decreases expression EXP Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases response to substance
multiple interactions
decreases expression 		ISO Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
Bleomycin results in decreased expression of CCL11 mRNA 		CTD PMID:16314464 PMID:29720568 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl12 C-C motif chemokine ligand 12 increases expression
multiple interactions
decreases expression 		ISO Bleomycin results in increased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
Bleomycin results in decreased expression of CCL12 mRNA 		CTD PMID:28434932 PMID:29720568 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780 		JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256 PMID:29175452 NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
Bleomycin results in decreased expression of CCL2 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein 		CTD PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
Bleomycin results in decreased expression of CCL3 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein
Bleomycin results in decreased expression of CCL3 protein 		CTD PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938 		JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231 		JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CCL5 mRNA
SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA] 		CTD PMID:32828905 NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Ccl9 C-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369 		JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression 		ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein 		CTD PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 More... NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734 		JBrowse link
G Ccng1 cyclin G1 increases expression ISO Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641 		JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
decreases response to substance
increases expression 		ISO CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of CCR2 mRNA 		CTD PMID:14609568 PMID:29033951 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100 		JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990 		JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression
increases expression
multiple interactions 		ISO Bleomycin affects the expression of CCR5 mRNA
Bleomycin results in increased expression of CCR5 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA] 		CTD PMID:26345256 PMID:30825431 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260 		JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079 		JBrowse link
G Cd14 CD14 molecule increases expression ISO Bleomycin results in increased expression of CD14 mRNA CTD PMID:36087614 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd2 Cd2 molecule increases expression ISO Bleomycin results in increased expression of CD2 mRNA CTD PMID:36087614 NCBI chr 2:188,710,895...188,724,044
Ensembl chr 2:188,710,900...188,724,026 		JBrowse link
G Cd33 CD33 molecule increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CD33 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA] 		CTD PMID:30825431 NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149 		JBrowse link
G Cd34 CD34 molecule multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CD34 protein] CTD PMID:30825431 NCBI chr13:106,480,313...106,500,844
Ensembl chr13:106,480,043...106,499,832 		JBrowse link
G Cd36 CD36 molecule decreases expression ISO Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cd44 CD44 molecule multiple interactions
increases expression 		ISO honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein] CTD PMID:32032644 NCBI chr 3:109,610,824...109,699,776
Ensembl chr 3:89,157,058...89,244,620 		JBrowse link
G Cd83 CD83 molecule increases expression ISO Bleomycin results in increased expression of CD83 mRNA CTD PMID:36087614 NCBI chr17:20,887,309...20,907,009
Ensembl chr17:20,887,309...20,907,083 		JBrowse link
G Cd86 CD86 molecule decreases expression ISO Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818 		JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 5:137,251,596...137,255,799
Ensembl chr 5:131,966,215...131,970,512 		JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression 		ISO
EXP 		12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein
Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] 		CTD PMID:28300665 PMID:28694203 PMID:32032644 PMID:34425168 PMID:35472619 More... NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775 		JBrowse link
G Cdh2 cadherin 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CDH2 protein
OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein] 		CTD PMID:35654123 NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167 		JBrowse link
G Cdk8 cyclin-dependent kinase 8 multiple interactions
increases expression 		ISO MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of CDK8 protein] CTD PMID:38460002 NCBI chr12:13,851,024...13,919,017
Ensembl chr12:8,737,262...8,804,177 		JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 PMID:29720568 PMID:32554301 NCBI chr20:7,150,820...7,161,373
Ensembl chr20:7,149,217...7,159,585 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
decreases response to substance
multiple interactions
increases response to substance 		ISO Bleomycin results in increased expression of CEBPB mRNA
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB protein results in increased susceptibility to Bleomycin 		CTD PMID:17177178 PMID:21998664 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473 		JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO Bleomycin results in decreased expression of CEMIP2 mRNA CTD PMID:33770205 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760 		JBrowse link
G Cenpe centromere protein E multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA] CTD PMID:30825431 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669 		JBrowse link
G Cert1 ceramide transporter 1 increases expression ISO Bleomycin results in increased expression of CERT1 mRNA CTD PMID:36087614 NCBI chr 2:27,882,546...27,987,090
Ensembl chr 2:27,882,555...27,987,074 		JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035 		JBrowse link
G Cfl1 cofilin 1 increases expression EXP Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587 		JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] 		CTD PMID:24933654 NCBI chr12:51,448,838...51,481,159
Ensembl chr12:45,788,827...45,821,286 		JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619 		JBrowse link
G Ckb creatine kinase B increases expression EXP Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315 		JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression EXP Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:15,185,380...15,339,977
Ensembl chr  X:15,185,451...15,334,264 		JBrowse link
G Cldn4 claudin 4 increases expression ISO Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436 		JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression EXP Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 5:147,453,702...147,513,455
Ensembl chr 5:147,453,712...147,513,452 		JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr 9:16,710,980...16,813,502
Ensembl chr 9:16,710,980...16,813,427 		JBrowse link
G Cltc clathrin heavy chain decreases expression EXP Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr10:72,014,984...72,073,308
Ensembl chr10:71,517,663...71,573,737 		JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099 		JBrowse link
G Col11a2 collagen type XI alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL11A2 mRNA CTD PMID:36087614 NCBI chr20:4,786,932...4,816,598
Ensembl chr20:4,786,929...4,815,985 		JBrowse link
G Col14a1 collagen type XIV alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL14A1 mRNA CTD PMID:36087614 NCBI chr 7:86,722,093...86,937,215
Ensembl chr 7:86,722,094...86,937,214 		JBrowse link
G Col18a1 collagen type XVIII alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL18A1 mRNA CTD PMID:36087614 NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593 		JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression 		ISO
EXP 		5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]]; [Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; baicalein inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] 		CTD PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 More... NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624 		JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of COL1A2 mRNA; Bleomycin results in increased expression of COL1A2 protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
Bleomycin results in decreased expression of COL1A2 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of COL1A2 protein] 		CTD PMID:19147827 PMID:25933445 PMID:35472619 PMID:37163307 PMID:37307957 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867 		JBrowse link
G Col22a1 collagen type XXII alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL22A1 mRNA CTD PMID:36087614 NCBI chr 7:103,730,939...103,968,452
Ensembl chr 7:103,731,037...103,968,462 		JBrowse link
G Col24a1 collagen type XXIV alpha 1 chain increases expression ISO Bleomycin results in increased expression of COL24A1 mRNA CTD PMID:36087614 NCBI chr 2:234,212,256...234,469,445
Ensembl chr 2:234,212,324...234,469,441 		JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression
increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of COL3A1 protein
Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein] 		CTD PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547 		JBrowse link
G Col4a4 collagen type IV alpha 4 chain increases expression ISO Bleomycin results in increased expression of COL4A4 mRNA CTD PMID:36087614 NCBI chr 9:83,833,173...83,875,436
Ensembl chr 9:83,755,515...83,875,876 		JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of COL5A1 protein
Bleomycin results in increased expression of COL5A1 mRNA 		CTD PMID:25933445 PMID:36087614 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588 		JBrowse link
G Col5a2 collagen type V alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL5A2 mRNA CTD PMID:36087614 NCBI chr 9:47,448,741...47,598,134
Ensembl chr 9:47,448,736...47,598,154 		JBrowse link
G Col5a3 collagen type V alpha 3 chain increases expression ISO Bleomycin results in increased expression of COL5A3 mRNA CTD PMID:36087614 NCBI chr 8:19,304,564...19,349,809
Ensembl chr 8:19,304,571...19,349,853 		JBrowse link
G Col6a3 collagen type VI alpha 3 chain increases expression ISO Bleomycin results in increased expression of COL6A3 mRNA CTD PMID:36087614 NCBI chr 9:91,361,578...91,439,434
Ensembl chr 9:91,361,583...91,439,471 		JBrowse link
G Col9a2 collagen type IX alpha 2 chain increases expression ISO Bleomycin results in increased expression of COL9A2 mRNA CTD PMID:36087614 NCBI chr 5:134,607,616...134,624,678
Ensembl chr 5:134,607,616...134,624,677 		JBrowse link
G Colq collagen like tail subunit of asymmetric acetylcholinesterase increases expression ISO Bleomycin results in increased expression of COLQ mRNA CTD PMID:36087614 NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107 		JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845 		JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression 		ISO tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075 		JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065 		JBrowse link
G Csf2 colony stimulating factor 2 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of CSF2 mRNA; Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of CSF2 mRNA] 		CTD PMID:18684396 PMID:28299617 PMID:29720568 PMID:32554301 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Csf2rb colony stimulating factor 2 receptor subunit beta increases expression ISO Bleomycin results in increased expression of CSF2RB2 mRNA CTD PMID:36087614 NCBI chr 7:109,876,919...109,901,589
Ensembl chr 7:109,886,425...109,904,157 		JBrowse link
G Csf3 colony stimulating factor 3 decreases expression EXP Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr13:49,709,928...49,731,141
Ensembl chr13:47,167,789...47,179,384 		JBrowse link
G Ctsa cathepsin A affects expression ISO Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215 		JBrowse link
G Ctsb cathepsin B affects expression ISO Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500 		JBrowse link
G Ctsh cathepsin H affects expression ISO Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824 		JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 2:183,086,437...183,114,483
Ensembl chr 2:183,086,437...183,114,483 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of CX3CL1 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of CX3CL1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CX3CL1 protein] 		CTD PMID:30825431 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 multiple interactions
increases expression 		ISO 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] CTD PMID:28299617 PMID:32554301 NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of CXCL10 mRNA; Bleomycin results in increased expression of CXCL10 protein
Bleomycin results in decreased expression of CXCL10 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein 		CTD PMID:26345256 PMID:29720568 PMID:33516805 PMID:36087614 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975 		JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 increases expression ISO Bleomycin results in increased expression of CXCL14 mRNA CTD PMID:36087614 NCBI chr17:8,317,930...8,325,956
Ensembl chr17:8,317,933...8,324,839 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
increases secretion
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of CXCL2 protein
Bleomycin results in increased secretion of CXCL2 protein
Bleomycin results in increased expression of CXCL2 mRNA
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein 		CTD PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
increases expression 		ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]
Bleomycin results in increased expression of CXCL1 protein
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of CXCL1 mRNA] 		CTD PMID:26600069 PMID:28299617 PMID:32554301 PMID:36087614 NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511 		JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435 		JBrowse link
G Cxcr1 C-X-C motif chemokine receptor 1 increases expression ISO Bleomycin results in increased expression of CXCR1 mRNA CTD PMID:36087614 NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084 		JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
increases expression 		ISO Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of CYBA mRNA] CTD PMID:35187969 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054 		JBrowse link
G Dbi diazepam binding inhibitor increases expression EXP Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of DDIT3 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of DDIT3 protein] 		CTD PMID:37163307 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Des desmin increases expression EXP Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699 		JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 8:59,875,537...59,900,947
Ensembl chr 8:50,978,051...51,004,479
Ensembl chr 1:50,978,051...51,004,479 		JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP
ISO 		Bleomycin results in increased expression of DLD protein CTD PMID:25933445 PMID:29733421 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795 		JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of DLL4 protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of DLL4 protein] CTD PMID:30825431 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Dnm1l dynamin 1-like increases expression ISO Bleomycin results in increased expression of DNM1L protein CTD PMID:37126650 NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482 		JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659 		JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257 		JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795 		JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression 		EXP Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839 		JBrowse link
G Egr1 early growth response 1 increases expression
multiple interactions
affects expression 		ISO Bleomycin results in increased expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
Bleomycin affects the expression of EGR1 mRNA 		CTD PMID:19147827 PMID:26345256 NCBI chr18:26,737,078...26,740,877
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Egr2 early growth response 2 affects expression ISO Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr20:21,050,149...21,055,201
Ensembl chr20:21,051,277...21,055,562 		JBrowse link
G Ehd1 EH-domain containing 1 decreases expression EXP Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212 		JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783 		JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656 		JBrowse link
G Eln elastin increases expression ISO Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Emcn endomucin increases expression
multiple interactions 		ISO Bleomycin results in increased expression of EMCN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA] 		CTD PMID:30825431 NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929 		JBrowse link
G Eng endoglin multiple interactions
increases expression 		ISO Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ENG protein] CTD PMID:30825431 NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230 		JBrowse link
G Epx eosinophil peroxidase increases expression EXP Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO Bleomycin results in decreased expression of ERRFI1 mRNA CTD PMID:33770205 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Espl1 extra spindle pole bodies like 1, separase multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA] CTD PMID:30825431 NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984 		JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010 		JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319 		JBrowse link
G Ezr ezrin decreases expression EXP Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression 		EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein 		CTD PMID:23656969 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578 		JBrowse link
G Faslg Fas ligand increases expression ISO Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Fgf1 fibroblast growth factor 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FGF1 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF1 protein] 		CTD PMID:30825431 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357 		JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF2 protein] 		CTD PMID:25582705 PMID:30825431 NCBI chr 2:122,164,454...122,218,796
Ensembl chr 2:120,236,328...120,291,221 		JBrowse link
G Fgf21 fibroblast growth factor 21 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of FGF21 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of FGF21 protein] 		CTD PMID:30825431 NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454 		JBrowse link
G Fgf7 fibroblast growth factor 7 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FGF7 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF7 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of FGF7 protein] 		CTD PMID:30825431 NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929 		JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928 		JBrowse link
G Fkbp10 FKBP prolyl isomerase 10 increases expression ISO Bleomycin results in increased expression of FKBP10 mRNA CTD PMID:36087614 NCBI chr10:85,345,434...85,357,998
Ensembl chr10:85,346,126...85,427,330 		JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]; TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of FN1 protein] 		CTD PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 More... NCBI chr 9:80,645,507...80,714,200
Ensembl chr 9:73,196,044...73,264,678 		JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity
multiple interactions 		ISO Bleomycin results in increased activity of FOS protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein] 		CTD PMID:12003776 PMID:37399107 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036 		JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838 		JBrowse link
G Foxq1 forkhead box Q1 increases expression ISO Bleomycin results in increased expression of FOXQ1 mRNA CTD PMID:36087614 NCBI chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377
Ensembl chr17:32,912,744...32,915,377 		JBrowse link
G Foxr1 forkhead box R1 increases expression ISO Bleomycin results in increased expression of FOXR1 mRNA CTD PMID:36087614 NCBI chr 8:44,760,587...44,768,696
Ensembl chr 8:44,760,948...44,768,880 		JBrowse link
G Fshb follicle stimulating hormone subunit beta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FSHB protein
thymoquinone inhibits the reaction [Bleomycin results in increased expression of FSHB protein] 		CTD PMID:34818114 NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370 		JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785 		JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression EXP Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602 		JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA] 		CTD PMID:28726637 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776 		JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression EXP Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844 		JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251 		JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr10:26,374,693...26,463,937
Ensembl chr10:26,374,694...26,464,346 		JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression EXP Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228 		JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr 1:205,793,910...205,813,704
Ensembl chr 1:205,793,895...205,813,695 		JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904 		JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA] 		CTD PMID:29033951 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression 		ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544 		JBrowse link
G Gda guanine deaminase decreases expression EXP Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416 		JBrowse link
G Glb1 galactosidase, beta 1 increases activity ISO Bleomycin results in increased activity of GLB1 protein CTD PMID:32554301 NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127 		JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression EXP Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086 		JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024 		JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510 		JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307 		JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation 		ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin decreases expression EXP Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions 		EXP Bleomycin results in decreased activity of GSR protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein] 		CTD PMID:26768587 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661 		JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 2:198,338,005...198,346,007
Ensembl chr 2:195,649,845...195,655,411 		JBrowse link
G H1f0 H1.0 linker histone affects expression EXP Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr 7:112,473,280...112,475,140
Ensembl chr 7:110,592,208...110,594,694 		JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression EXP Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr17:41,486,574...41,487,355
Ensembl chr17:41,486,560...41,487,403 		JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239
Ensembl chr 4:44,671,786...44,673,239 		JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 6:31,907,801...31,947,434
Ensembl chr 6:26,187,956...26,227,869 		JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698 		JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Bleomycin affects the expression of HBB protein CTD PMID:25933445 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbb-b2 hemoglobin, beta adult minor chain affects expression EXP Bleomycin affects the expression of HBB-B2 protein CTD PMID:25933445 NCBI chr 1:158,243,696...158,245,076
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441 		JBrowse link
G Hcls1 hematopoietic cell specific Lyn substrate 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA] CTD PMID:30825431 NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014 		JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases secretion
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
Bleomycin results in increased secretion of HGF protein
Bleomycin results in increased expression of HGF mRNA
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of HGF protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of HGF protein] 		CTD PMID:16115399 PMID:22687607 PMID:29408570 PMID:30825431 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression 		ISO [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hist1h2bg histone cluster 1, H2bg decreases expression EXP Bleomycin results in decreased expression of HIST1H2BG protein CTD PMID:25933445 NCBI chr17:41,571,234...41,572,202
Ensembl chr17:41,571,210...41,571,896 		JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Bleomycin results in decreased expression of HMCES mRNA CTD PMID:33770205 NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616 		JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression 		EXP
ISO 		protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA] 		CTD PMID:25582705 PMID:32278510 NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565 		JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression 		ISO
EXP 		Bleomycin results in increased expression of HMOX1 protein
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
Bleomycin results in increased expression of HMOX1 mRNA
Bleomycin results in decreased expression of HMOX1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA] 		CTD PMID:16317386 PMID:26093215 PMID:26768587 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249 		JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression EXP Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306 		JBrowse link
G Hpx hemopexin increases expression EXP Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328 		JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268 		JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:22,997,962...23,012,293
Ensembl chr 7:21,110,457...21,124,788 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A increases expression
multiple interactions 		ISO Bleomycin results in increased expression of HSPA1A mRNA
geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1A mRNA] 		CTD PMID:37307957 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B increases expression
multiple interactions 		ISO Bleomycin results in increased expression of HSPA1B mRNA
geranylgeranylacetone promotes the reaction [Bleomycin results in increased expression of HSPA1B mRNA] 		CTD PMID:37307957 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of HSPA5 protein
pachymic acid inhibits the reaction [Bleomycin results in increased expression of HSPA5 protein] 		CTD PMID:25933445 PMID:37163307 NCBI chr 3:38,453,016...38,457,475
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO 		Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445 PMID:29733421 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089 		JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150 		JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A decreases expression EXP Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651 		JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B decreases expression EXP Bleomycin results in decreased expression of HTR5B mRNA CTD PMID:15808516 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835 		JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951 PMID:29720568 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025 		JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of IFITM1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA] 		CTD PMID:30825431 NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169 		JBrowse link
G Ifng interferon gamma increases expression
decreases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of IFNG mRNA
Bleomycin results in decreased expression of IFNG mRNA
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein 		CTD PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 More... NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375 		JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:24,169,608...24,249,446
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Ikbip IKBKB interacting protein increases expression ISO Bleomycin results in increased expression of IKBIP mRNA CTD PMID:36087614 NCBI chr 7:25,579,865...25,598,548
Ensembl chr 7:25,579,832...25,605,162 		JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
increases secretion 		ISO Bleomycin results in increased expression of IL10 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL10 protein] 		CTD PMID:29175452 PMID:37898439 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313 		JBrowse link
G Il10ra interleukin 10 receptor subunit alpha increases expression ISO Bleomycin results in increased expression of IL10RA mRNA CTD PMID:36087614 NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061 		JBrowse link
G Il12b interleukin 12B increases expression ISO Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903 		JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression ISO Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289 		JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions 		ISO IL13 gene mutant form results in decreased susceptibility to Bleomycin
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA] 		CTD PMID:15322207 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737 		JBrowse link
G Il13ra1 interleukin 13 receptor subunit alpha 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA] CTD PMID:30825431 PMID:36087614 NCBI chr  X:115,348,822...115,408,682
Ensembl chr  X:115,348,860...115,408,681
Ensembl chr11:115,348,860...115,408,681 		JBrowse link
G Il17a interleukin 17A multiple interactions
increases expression 		ISO Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] CTD PMID:35716765 NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889 		JBrowse link
G Il17rd interleukin 17 receptor D increases expression ISO Bleomycin results in increased expression of IL17RD mRNA CTD PMID:36087614 NCBI chr16:2,228,438...2,295,122
Ensembl chr16:2,228,287...2,292,556 		JBrowse link
G Il17re interleukin 17 receptor E increases expression ISO Bleomycin results in increased expression of IL17RE mRNA CTD PMID:36087614 NCBI chr 4:146,604,547...146,618,206
Ensembl chr 4:146,605,526...146,618,206 		JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression 		ISO 5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]; IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL1A mRNA]
Bleomycin results in increased expression of IL1A protein 		CTD PMID:8317554 PMID:28299617 PMID:29175452 PMID:32554301 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822 		JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases expression
increases secretion
affects expression 		ISO
EXP 		12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of IL1B mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of IL1B mRNA; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]
Bleomycin affects the expression of IL1B mRNA 		CTD PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rl1 interleukin 1 receptor-like 1 increases expression ISO Bleomycin results in increased expression of IL1RL1 mRNA; Bleomycin results in increased expression of IL1RL1 protein CTD PMID:37399107 NCBI chr 9:42,661,694...42,727,266
Ensembl chr 9:42,697,192...42,727,256 		JBrowse link
G Il2 interleukin 2 multiple interactions EXP [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein CTD PMID:33516805 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566 		JBrowse link
G Il33 interleukin 33 increases expression ISO Bleomycin results in increased expression of IL33 mRNA; Bleomycin results in increased expression of IL33 protein CTD PMID:36087614 PMID:37399107 NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373 		JBrowse link
G Il4 interleukin 4 increases expression
decreases response to substance
multiple interactions
affects response to substance
increases secretion 		ISO Bleomycin results in increased expression of IL4 mRNA
IL4 gene mutant form results in decreased susceptibility to Bleomycin
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]
IL4 protein affects the susceptibility to Bleomycin
Bleomycin results in increased secretion of IL4 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of IL4 protein] 		CTD PMID:11554783 PMID:12574379 PMID:15322207 PMID:30033591 PMID:37898439 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750 		JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
increases secretion 		ISO
EXP 		Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; astragalin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; aurantio-obtusin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; caffeic acid inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; eleutheroside E inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; linarin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; rhoifolin inhibits the reaction [Bleomycin results in increased secretion of IL6 protein]; scoparone inhibits the reaction [Bleomycin results in increased secretion of IL6 protein] 		CTD PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Il7 interleukin 7 increases expression ISO Bleomycin results in increased expression of IL7 protein CTD PMID:36087614 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Insig1 insulin induced gene 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] CTD PMID:30825431 NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952 		JBrowse link
G Itgb2 integrin subunit beta 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ITGB2 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA] 		CTD PMID:30825431 NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression EXP Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513 		JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity
increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased activity of JUN protein
Bleomycin results in increased phosphorylation of JUN protein
Bleomycin results in increased expression of [JUN protein binds to FOS protein]; Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein] 		CTD PMID:12003776 PMID:35716765 PMID:37399107 NCBI chr 5:115,009,900...115,012,993
Ensembl chr 5:109,893,145...109,897,656 		JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of KEAP1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]
Ephedrine inhibits the reaction [Bleomycin results in increased expression of KEAP1 protein] 		CTD PMID:26768587 PMID:37778983 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862 		JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr 9:1,862,555...1,872,403
Ensembl chr 9:1,862,899...1,872,451 		JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions 		ISO Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein 		CTD PMID:29733421 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652 		JBrowse link
G Kl Klotho decreases expression ISO Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080 		JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Bleomycin results in increased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:181,730,343...181,760,899
Ensembl chr 4:180,004,580...180,027,283 		JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt13 keratin 13 increases expression ISO Bleomycin results in increased expression of KRT13 mRNA CTD PMID:36087614 NCBI chr10:85,051,887...85,056,099
Ensembl chr10:85,051,889...85,056,084 		JBrowse link
G Krt19 keratin 19 decreases expression EXP Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799 		JBrowse link
G Krt8 keratin 8 multiple interactions
decreases expression 		ISO Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 mRNA]; Ephedrine inhibits the reaction [Bleomycin results in decreased expression of KRT8 protein]
Bleomycin results in decreased expression of KRT8 mRNA; Bleomycin results in decreased expression of KRT8 protein 		CTD PMID:37778983 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728 		JBrowse link
G Krt87 keratin 87 increases expression ISO Bleomycin results in increased expression of KRT87 mRNA CTD PMID:36087614 NCBI chr 7:132,547,388...132,555,005
Ensembl chr 7:132,548,141...132,554,978 		JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression EXP Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359 		JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292 		JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Lcp1 lymphocyte cytosolic protein 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LCP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA] 		CTD PMID:30825431 NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680 		JBrowse link
G Ldhal1 lactate dehydrogenase A like 1 decreases expression EXP Bleomycin results in decreased expression of LDHAL1 protein CTD PMID:25933445 NCBI chr 8:30,363,220...30,364,836 JBrowse link
G Lep leptin increases expression ISO Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262 		JBrowse link
G Lgals3 galectin 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LGALS3 protein
NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein] 		CTD PMID:26526764 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025 		JBrowse link
G Lgals9 galectin 9 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of LGALS9 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA] 		CTD PMID:30825431 NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045 		JBrowse link
G Lhb luteinizing hormone subunit beta multiple interactions
increases expression 		ISO thymoquinone inhibits the reaction [Bleomycin results in increased expression of LHB protein] CTD PMID:34818114 NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972 		JBrowse link
G Lhfpl6 LHFPL tetraspan subfamily member 6 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of LHFPL6 mRNA] CTD PMID:30825431 NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443 		JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617 		JBrowse link
G Liph lipase H decreases expression ISO Bleomycin results in decreased expression of LIPH mRNA CTD PMID:33770205 NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625 		JBrowse link
G Lmna lamin A/C increases expression EXP Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Lpxn leupaxin multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA] CTD PMID:30825431 NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084 		JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106 		JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072 		JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form] 		CTD PMID:31302203 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
Ensembl chr16:49,665,791...49,677,690 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr11:97,462,025...97,529,193
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 1:190,797,189...190,803,411
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions
increases phosphorylation 		ISO Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein] CTD PMID:35716765 NCBI chr16:8,645,171...8,728,225
Ensembl chr16:8,638,924...8,721,981 		JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression EXP Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein 		CTD PMID:25933445 PMID:29733421 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271 		JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance ISO MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689 		JBrowse link
G Mepce methylphosphate capping enzyme increases expression ISO Bleomycin results in increased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions
increases phosphorylation 		ISO Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein 		CTD PMID:22687607 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554 		JBrowse link
G Mfn1 mitofusin 1 decreases expression ISO Bleomycin results in decreased expression of MFN1 protein CTD PMID:37126650 NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640 		JBrowse link
G Mfn2 mitofusin 2 decreases expression ISO Bleomycin results in decreased expression of MFN2 protein CTD PMID:37126650 NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342 		JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
Ensembl chr 4:12,790,902...12,799,504 		JBrowse link
G Mir100 microRNA 100 decreases expression EXP Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304 		JBrowse link
G Mir101-2 microRNA 101-2 decreases expression EXP
ISO 		Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445 PMID:28726637 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467 		JBrowse link
G Mir101a microRNA 101a multiple interactions
decreases expression 		ISO
EXP 		MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
Bleomycin results in decreased expression of MIR101A mRNA 		CTD PMID:25933445 PMID:28726637 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410 		JBrowse link
G Mir106b microRNA 106b affects expression EXP Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425 		JBrowse link
G Mir107 microRNA 107 decreases expression EXP Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853 		JBrowse link
G Mir10a microRNA 10a decreases expression EXP Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280 		JBrowse link
G Mir10b microRNA 10b decreases expression EXP Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546 		JBrowse link
G Mir1224 microRNA 1224 increases expression EXP Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986 		JBrowse link
G Mir1249 microRNA 1249 affects expression EXP Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712 		JBrowse link
G Mir125a microRNA 125a affects expression EXP Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710 		JBrowse link
G Mir126a microRNA 126a decreases expression EXP Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 3:9,415,063...9,415,180
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir130a microRNA 130a decreases expression EXP Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629 		JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression EXP Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir133b microRNA 133b decreases expression EXP Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217 		JBrowse link
G Mir140 microRNA 140 affects expression EXP Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir141 microRNA 141 affects expression EXP Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332 		JBrowse link
G Mir142 microRNA 142 decreases expression
increases expression 		EXP Bleomycin results in decreased expression of MIR142 mRNA
Bleomycin results in increased expression of MIR142 mRNA 		CTD PMID:25933445 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967 		JBrowse link
G Mir143 microRNA 143 decreases expression EXP Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110 		JBrowse link
G Mir144 microRNA 144 decreases expression EXP Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430 		JBrowse link
G Mir145 microRNA 145 decreases expression EXP Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727 		JBrowse link
G Mir146a microRNA 146a affects expression EXP Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610 		JBrowse link
G Mir146b microRNA 146b increases expression EXP Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525 		JBrowse link
G Mir148b microRNA 148b decreases expression EXP Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494 		JBrowse link
G Mir150 microRNA 150 affects expression EXP Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108 		JBrowse link
G Mir151 microRNA 151 decreases expression EXP Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr 7:105,172,377...105,172,473 JBrowse link
G Mir152 microRNA 152 decreases expression EXP Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir15b microRNA 15b affects expression EXP Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297 		JBrowse link
G Mir16-2 microRNA 16-2 decreases expression EXP Bleomycin results in decreased expression of MIR16-2 mRNA CTD PMID:25933445 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443 		JBrowse link
G Mir17 microRNA 17 affects expression EXP Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712 		JBrowse link
G Mir181a-1 microRNA 181a-1 decreases expression EXP Bleomycin results in decreased expression of MIR181A-1 mRNA CTD PMID:25933445 NCBI chr13:49,485,527...49,485,626 JBrowse link
G Mir181c microRNA 181c decreases expression EXP Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628 		JBrowse link
G Mir181d microRNA 181d decreases expression EXP Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788 		JBrowse link
G Mir182 microRNA 182 increases expression
affects expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of MIR182 mRNA
Bleomycin affects the expression of MIR182 mRNA
MIR182 affects the reaction [Bleomycin results in decreased expression of SMAD7 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of FN1 protein]; MIR182 affects the reaction [Bleomycin results in increased expression of TGFB1 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein] 		CTD PMID:25933445 PMID:31884830 NCBI chr 4:58,784,818...58,784,879
Ensembl chr 4:58,784,818...58,784,879 		JBrowse link
G Mir183 microRNA 183 affects expression EXP Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723 		JBrowse link
G Mir185 microRNA 185 decreases expression EXP Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795 		JBrowse link
G Mir186 microRNA 186 decreases expression EXP Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891 		JBrowse link
G Mir188 microRNA 188 affects expression EXP Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794 		JBrowse link
G Mir18a microRNA 18a increases expression EXP Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860 		JBrowse link
G Mir193 microRNA 193 decreases expression EXP Bleomycin results in decreased expression of MIR193 mRNA CTD PMID:25933445 NCBI chr10:64,672,354...64,672,439 JBrowse link
G Mir1949 microRNA 1949 increases expression EXP Bleomycin results in increased expression of MIR1949 mRNA CTD PMID:25933445 NCBI chr18:27,155,595...27,155,691
Ensembl chr18:27,155,595...27,155,691 		JBrowse link
G Mir195 microRNA 195 decreases expression EXP Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924 		JBrowse link
G Mir199a2 microRNA 199a-2 affects expression EXP Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063 		JBrowse link
G Mir19a microRNA 19a affects expression EXP Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir200a microRNA 200a decreases expression EXP Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir200b microRNA 200b decreases expression EXP Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366 		JBrowse link
G Mir200c microRNA 200c decreases expression EXP Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir203-2 microRNA 203-2 decreases expression EXP Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656 		JBrowse link
G Mir204 microRNA 204 decreases expression EXP Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040 		JBrowse link
G Mir20a microRNA 20a affects expression EXP Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168 		JBrowse link
G Mir20b microRNA 20b affects expression EXP Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282 		JBrowse link
G Mir21 microRNA 21 increases expression EXP Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348 		JBrowse link
G Mir210 microRNA 210 decreases expression EXP Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454 		JBrowse link
G Mir211 microRNA 211 affects expression EXP Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644 		JBrowse link
G Mir212 microRNA 212 affects expression EXP Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513 		JBrowse link
G Mir214 microRNA 214 affects expression EXP Bleomycin affects the expression of MIR214 mRNA CTD PMID:25933445 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir22 microRNA 22 affects expression EXP Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133 		JBrowse link
G Mir221 microRNA 221 decreases expression EXP Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Mir222 microRNA 222 decreases expression
affects expression 		EXP Bleomycin results in decreased expression of MIR222 mRNA
Bleomycin affects the expression of MIR222 mRNA 		CTD PMID:25933445 PMID:34425168 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006 		JBrowse link
G Mir223 microRNA 223 affects expression EXP Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996 		JBrowse link
G Mir23a microRNA 23a decreases expression EXP Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mir23b microRNA 23b decreases expression EXP Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763 		JBrowse link
G Mir24-2 microRNA 24-2 decreases expression EXP Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790 		JBrowse link
G Mir25 microRNA 25 affects expression EXP Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015 		JBrowse link
G Mir26a microRNA 26a decreases expression EXP
ISO 		Bleomycin results in decreased expression of MIR26A mRNA
Bleomycin results in decreased expression of MIR26A-1 		CTD PMID:25933445 PMID:35785413 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378 		JBrowse link
G Mir26b microRNA 26b decreases expression EXP Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680 		JBrowse link
G Mir27a microRNA 27a decreases expression EXP Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917 		JBrowse link
G Mir27b microRNA 27b decreases expression EXP Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529 		JBrowse link
G Mir28 microRNA 28 decreases expression EXP Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608 		JBrowse link
G Mir290 microRNA 290 increases expression EXP Bleomycin results in increased expression of MIR290 mRNA CTD PMID:25933445 NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728 		JBrowse link
G Mir296 microRNA 296 affects expression EXP Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915 		JBrowse link
G Mir2985 microRNA 2985 affects expression EXP Bleomycin affects the expression of MIR2985 mRNA CTD PMID:25933445 NCBI chr 2:165,956,389...165,956,498
Ensembl chr 2:165,956,389...165,956,498 		JBrowse link
G Mir29a microRNA 29a decreases expression EXP Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir29c microRNA 29c decreases expression EXP Bleomycin results in decreased expression of MIR29C mRNA CTD PMID:25933445 NCBI chr13:106,570,899...106,570,986 JBrowse link
G Mir301a microRNA 301a affects expression EXP Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435 		JBrowse link
G Mir3085 microRNA 3085 decreases expression EXP Bleomycin results in decreased expression of MIR3085 mRNA CTD PMID:25933445 NCBI chr 1:241,088,905...241,088,993
Ensembl chr 1:241,088,905...241,088,993 		JBrowse link
G Mir30a microRNA 30a decreases expression EXP Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670 		JBrowse link
G Mir30b microRNA 30b decreases expression EXP Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675 		JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression EXP Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425 		JBrowse link
G Mir30d microRNA 30d decreases expression EXP Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472 		JBrowse link
G Mir30e microRNA 30e decreases expression EXP Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323 		JBrowse link
G Mir31 microRNA 31 decreases expression EXP Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir32 microRNA 32 increases expression EXP Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152 		JBrowse link
G Mir320a microRNA 320a decreases expression EXP Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473 		JBrowse link
G Mir322 microRNA 322 decreases expression EXP Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:132,806,594...132,806,688
Ensembl chr  X:132,806,594...132,806,688 		JBrowse link
G Mir324 microRNA 324 affects expression EXP Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766 		JBrowse link
G Mir326 microRNA 326 decreases expression EXP Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123 		JBrowse link
G Mir328 microRNA 328 affects expression EXP Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849 		JBrowse link
G Mir33 microRNA 33 decreases expression EXP Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923 		JBrowse link
G Mir330 microRNA 330 decreases expression EXP Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274 		JBrowse link
G Mir331 microRNA 331 decreases expression EXP Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485 		JBrowse link
G Mir338 microRNA 338 decreases expression EXP Bleomycin results in decreased expression of MIR338 mRNA CTD PMID:25933445 NCBI chr10:105,297,923...105,297,988 JBrowse link
G Mir340 microRNA 340 increases expression EXP Bleomycin results in increased expression of MIR340 mRNA CTD PMID:25933445 NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665 		JBrowse link
G Mir342 microRNA 342 decreases expression EXP Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367 		JBrowse link
G Mir345 microRNA 345 decreases expression EXP Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122 		JBrowse link
G Mir347 microRNA mir-347 decreases expression EXP Bleomycin results in decreased expression of MIR347 mRNA CTD PMID:25933445
G Mir3473 microRNA 3473 increases expression EXP Bleomycin results in increased expression of MIR3473 mRNA CTD PMID:25933445 NCBI chr13:39,499,246...39,499,312
Ensembl chr13:39,499,246...39,499,312 		JBrowse link
G Mir34a microRNA 34a affects expression
decreases expression 		EXP Bleomycin affects the expression of MIR34A mRNA
Bleomycin results in decreased expression of MIR34A mRNA 		CTD PMID:25933445 PMID:34425168 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103 		JBrowse link
G Mir34b microRNA 34b decreases expression EXP Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327 		JBrowse link
G Mir34c microRNA 34c decreases expression EXP Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802 		JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Bleomycin results in decreased expression of MIR352 mRNA CTD PMID:25933445
G Mir3573 microRNA 3573 decreases expression EXP Bleomycin results in decreased expression of MIR3573 mRNA CTD PMID:25933445 NCBI chr  X:64,259,096...64,259,167
Ensembl chr  X:64,259,096...64,259,167 		JBrowse link
G Mir3584 microRNA 3584 affects expression EXP Bleomycin affects the expression of MIR3584 mRNA CTD PMID:25933445 NCBI chr 1:246,786,249...246,786,329
Ensembl chr 1:246,786,249...246,786,329 		JBrowse link
G Mir361 microRNA 361 decreases expression EXP Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275 		JBrowse link
G Mir362 microRNA 362 affects expression EXP Bleomycin affects the expression of MIR362 mRNA CTD PMID:25933445 NCBI chr  X:15,254,615...15,254,679
Ensembl chr  X:15,254,615...15,254,679 		JBrowse link
G Mir365b microRNA 365b decreases expression EXP Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr10:64,686,255...64,686,340
Ensembl chr10:64,686,252...64,686,351 		JBrowse link
G Mir374b microRNA 374b decreases expression EXP Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:68,591,732...68,591,799
Ensembl chr  X:68,591,732...68,591,799 		JBrowse link
G Mir375 microRNA 375 decreases expression EXP Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985 		JBrowse link
G Mir378 microRNA 378 decreases expression EXP Bleomycin results in decreased expression of MIR378 mRNA CTD PMID:25933445 NCBI chr18:54,858,559...54,858,623 JBrowse link
G Mir409 microRNA 409 affects expression EXP Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr 6:128,757,780...128,757,856
Ensembl chr 6:128,757,779...128,757,858 		JBrowse link
G Mir423 microRNA 423 decreases expression EXP Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226 		JBrowse link
G Mir425 microRNA 425 affects expression EXP Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637 		JBrowse link
G Mir429 microRNA 429 decreases expression EXP Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543 		JBrowse link
G Mir449a microRNA 449a affects expression EXP Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804 		JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:132,801,380...132,801,470
Ensembl chr  X:132,801,380...132,801,470 		JBrowse link
G Mir451a microRNA 451a decreases expression EXP
ISO 		Bleomycin results in decreased expression of MIR451A mRNA
Bleomycin results in decreased expression of MIR451A protein 		CTD PMID:25933445 PMID:34460027 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Mir466b-1 microRNA mir-466b-1 decreases expression EXP Bleomycin results in decreased expression of MIR466B-1 mRNA CTD PMID:25933445 NCBI chr17:68,035,758...68,035,843 JBrowse link
G Mir483 microRNA 483 affects expression EXP Bleomycin affects the expression of MIR483 mRNA CTD PMID:25933445 NCBI chr 1:197,818,396...197,818,468
Ensembl chr 1:197,818,396...197,818,468 		JBrowse link
G Mir494 microRNA 494 decreases expression EXP Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793 		JBrowse link
G Mir497 microRNA 497 decreases expression EXP Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584 		JBrowse link
G Mir500 microRNA 500 affects expression EXP Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:15,258,778...15,258,857
Ensembl chr  X:15,258,768...15,258,859 		JBrowse link
G Mir503 microRNA 503 decreases expression EXP Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:132,806,303...132,806,373
Ensembl chr  X:132,806,303...132,806,373 		JBrowse link
G Mir511 microRNA 511 increases expression EXP Bleomycin results in increased expression of MIR511 mRNA CTD PMID:25933445 NCBI chr17:77,279,415...77,279,493
Ensembl chr17:77,279,415...77,279,493 		JBrowse link
G Mir532 microRNA 532 affects expression EXP Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393 		JBrowse link
G Mir542 microRNA 542 decreases expression EXP Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:132,802,623...132,802,701
Ensembl chr  X:132,802,623...132,802,701 		JBrowse link
G Mir6215 microRNA 6215 decreases expression EXP Bleomycin results in decreased expression of MIR6215 mRNA CTD PMID:25933445 NCBI chr 5:151,850,759...151,850,825
Ensembl chr 5:151,850,759...151,850,825 		JBrowse link
G Mir6216 microRNA 6216 decreases expression EXP Bleomycin results in decreased expression of MIR6216 mRNA CTD PMID:25933445 NCBI chr 3:44,756,861...44,756,938
Ensembl chr 3:44,756,861...44,756,938 		JBrowse link
G Mir6328 microRNA 6328 affects expression EXP Bleomycin affects the expression of MIR6328 mRNA CTD PMID:25933445 NCBI chr20:2,885,300...2,885,396
Ensembl chr20:2,885,300...2,885,396 		JBrowse link
G Mir652 microRNA 652 affects expression EXP Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373 		JBrowse link
G Mir672 microRNA 672 decreases expression EXP Bleomycin results in decreased expression of MIR672 mRNA CTD PMID:25933445 NCBI chr  X:69,126,598...69,126,677
Ensembl chr  X:69,126,598...69,126,677 		JBrowse link
G Mir674 microRNA 674 affects expression EXP Bleomycin affects the expression of MIR674 mRNA CTD PMID:25933445 NCBI chr 3:104,053,133...104,053,209
Ensembl chr 3:104,053,133...104,053,209 		JBrowse link
G Mir702 microRNA 702 affects expression EXP Bleomycin affects the expression of MIR702 mRNA CTD PMID:25933445 NCBI chr12:19,681,809...19,681,915
Ensembl chr12:19,681,809...19,681,915 		JBrowse link
G Mir872 microRNA 872 decreases expression EXP Bleomycin results in decreased expression of MIR872 mRNA CTD PMID:25933445 NCBI chr 5:109,539,086...109,539,166
Ensembl chr 5:109,539,086...109,539,166 		JBrowse link
G Mir93 microRNA 93 affects expression EXP Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221 		JBrowse link
G Mir96 microRNA 96 affects expression EXP Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516 		JBrowse link
G Mir98 microRNA 98 decreases expression EXP Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342 		JBrowse link
G Mir99a microRNA 99a decreases expression EXP Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523 		JBrowse link
G Mir99b microRNA 99b decreases expression EXP Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090 		JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270 		JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990 		JBrowse link
G Mirlet7e microRNA let-7e decreases expression EXP Bleomycin results in decreased expression of MIRLET7E mRNA CTD PMID:25933445 NCBI chr 1:58,677,180...58,677,272 JBrowse link
G Mirlet7i microRNA let-7i decreases expression EXP Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571 		JBrowse link
G Mkln1 muskelin 1 multiple interactions
increases expression 		ISO MKLN1 mRNA alternative form affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of CDK8 protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of VIM protein]
Bleomycin results in increased expression of MKLN1 mRNA alternative form 		CTD PMID:38460002 NCBI chr 4:59,815,912...60,124,047
Ensembl chr 4:60,002,464...60,123,993 		JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression 		EXP
ISO 		allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
Bleomycin results in increased expression of and results in increased secretion of MMP2 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP2 mRNA] 		CTD PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 PMID:35716765 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp23 matrix metallopeptidase 23 increases expression ISO Bleomycin results in increased expression of MMP23 mRNA CTD PMID:36087614 NCBI chr 5:166,239,643...166,242,734
Ensembl chr 5:166,239,644...166,242,433 		JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression 		ISO [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; Apigenin inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA] 		CTD PMID:28299617 PMID:28434932 PMID:32554301 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of MMP7 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of MMP7 protein] 		CTD PMID:32032644 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902 		JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Bleomycin results in increased expression of and results in increased secretion of MMP9 protein; Curcumin inhibits the reaction [Bleomycin results in increased expression of and results in increased secretion of MMP9 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein] 		CTD PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 More... NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mpo myeloperoxidase multiple interactions
increases activity
increases expression 		ISO
EXP 		Oils, Volatile inhibits the reaction [Bleomycin results in increased activity of MPO protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein] 		CTD PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 PMID:28850077 NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819 		JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857 		JBrowse link
G Msn moesin decreases expression EXP Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628 		JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA] 		CTD PMID:18684396 PMID:26093215 NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475 		JBrowse link
G Mucl3 mucin like 3 increases expression ISO Bleomycin results in increased expression of MUCL3 mRNA CTD PMID:36087614 NCBI chr20:3,100,652...3,108,569
Ensembl chr20:3,100,679...3,108,569 		JBrowse link
G Mug2 murinoglobulin 2 increases expression EXP Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 4:155,164,061...155,236,894
Ensembl chr 4:155,164,011...155,236,475 		JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Bleomycin results in decreased expression of MXI1 mRNA CTD PMID:33770205 NCBI chr 1:262,329,274...262,389,037
Ensembl chr 1:252,323,303...252,383,681 		JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance ISO MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr 7:95,483,105...95,488,031
Ensembl chr 7:93,593,705...93,598,630 		JBrowse link
G Myh11 myosin heavy chain 11 decreases expression EXP Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459 		JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myl12b myosin light chain 12B increases expression EXP Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr 9:110,873,855...110,888,187 JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363 		JBrowse link
G Myl6 myosin light chain 6 increases expression EXP Bleomycin results in increased expression of MYL6 protein CTD PMID:25933445 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791 		JBrowse link
G Myo1c myosin 1C decreases expression EXP Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr10:60,498,372...60,520,752
Ensembl chr10:60,498,280...60,520,752 		JBrowse link
G Myo1e myosin IE decreases expression ISO Bleomycin results in decreased expression of MYO1E mRNA CTD PMID:33770205 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169 		JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593 		JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions
increases expression 		ISO MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
increases phosphorylation
decreases expression
multiple interactions
increases expression 		ISO
EXP 		Bleomycin affects the localization of NFE2L2 protein
Bleomycin results in increased phosphorylation of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 protein
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein]
Bleomycin results in increased expression of NFE2L2 protein
Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein
Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; celastrol inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]
Ephedrine inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein] 		CTD PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 PMID:37778983 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
increases expression
multiple interactions 		ISO
EXP 		Bleomycin results in increased activity of NFKB1 protein
Bleomycin results in increased expression of NFKB1 mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein] 		CTD PMID:12003776 PMID:26093215 PMID:26526764 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nfkbiz NFKB inhibitor zeta increases expression
multiple interactions 		ISO Bleomycin results in increased expression of NFKBIZ mRNA; Bleomycin results in increased expression of NFKBIZ protein
5,7-dihydroxy-6-methoxy-2-phenylchromen-4-one inhibits the reaction [Bleomycin results in increased expression of NFKBIZ mRNA]; methyl caffeate inhibits the reaction [Bleomycin results in increased expression of NFKBIZ protein] 		CTD PMID:28299617 PMID:32554301 NCBI chr11:44,782,676...44,810,722
Ensembl chr11:44,782,676...44,810,723 		JBrowse link
G Nherf1 NHERF family PDZ scaffold protein 1 increases expression EXP Bleomycin results in increased expression of NHERF1 protein CTD PMID:25933445 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598 		JBrowse link
G Nherf2 NHERF family PDZ scaffold protein 2 decreases expression EXP Bleomycin results in decreased expression of NHERF2 protein CTD PMID:25933445 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049 		JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024 		JBrowse link
G Nlrp10 NLR family, pyrin domain containing 10 increases expression ISO Bleomycin results in increased expression of NLRP10 mRNA CTD PMID:36087614 NCBI chr 1:162,922,806...162,930,363
Ensembl chr 1:162,922,806...162,930,363 		JBrowse link
G Nmbr neuromedin B receptor decreases expression EXP Bleomycin results in decreased expression of NMBR mRNA CTD PMID:15808516 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462 		JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Bleomycin results in increased expression of NME2 protein CTD PMID:25933445 NCBI chr10:78,898,097...78,903,514
Ensembl chr10:78,897,770...78,903,538
Ensembl chr20:78,897,770...78,903,538 		JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
increases secretion 		ISO
EXP 		Bleomycin results in increased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein
Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased secretion of NOS2 protein
yupingfeng inhibits the reaction [Bleomycin results in increased secretion of NOS2 protein] 		CTD PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Notch4 notch receptor 4 increases expression ISO Bleomycin results in increased expression of NOTCH4 mRNA CTD PMID:36087614 NCBI chr20:4,160,362...4,184,466
Ensembl chr20:4,160,445...4,184,465 		JBrowse link
G Nox4 NADPH oxidase 4 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of NOX4 mRNA
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of NOX4 mRNA] 		CTD PMID:35187969 PMID:37307957 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406 		JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP Bleomycin results in increased expression of NPM1 protein CTD PMID:25933445 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
Ensembl chr  X:17,739,941...17,751,645 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity
multiple interactions 		EXP Bleomycin results in decreased activity of NQO1 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein] 		CTD PMID:26768587 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Bleomycin results in decreased expression of NR3C1 mRNA CTD PMID:15808516 NCBI chr18:31,522,783...31,644,508
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Bleomycin results in decreased expression of NR3C2 mRNA CTD PMID:15808516 NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885 		JBrowse link
G Nucb2 nucleobindin 2 increases expression EXP Bleomycin results in increased expression of NUCB2 protein CTD PMID:25933445 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:196,777,973...196,797,754
Ensembl chr 1:187,347,865...187,367,682 		JBrowse link
G Ogg1 8-oxoguanine DNA glycosylase increases expression
affects response to substance
multiple interactions 		ISO Bleomycin results in increased expression of OGG1 protein
OGG1 protein affects the susceptibility to Bleomycin
OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of OGG1 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of OGG1 protein] 		CTD PMID:35654123 NCBI chr 4:146,474,701...146,481,959
Ensembl chr 4:146,474,750...146,484,766 		JBrowse link
G Osr1 odd-skipped related transcription factor 1 increases expression ISO Bleomycin results in increased expression of OSR1 protein CTD PMID:34460027 NCBI chr 6:32,369,561...32,380,822
Ensembl chr 6:32,373,816...32,380,817 		JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression EXP Bleomycin results in increased expression of OSTF1 protein CTD PMID:25933445 NCBI chr 1:216,002,037...216,049,226
Ensembl chr 1:216,002,044...216,049,221 		JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP Bleomycin results in increased expression of P4HB protein CTD PMID:25933445 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500 		JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression EXP Bleomycin results in increased expression of PABPC1 protein CTD PMID:25933445 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
increases cleavage
multiple interactions 		ISO
EXP 		Bleomycin results in increased expression of PARP1 protein
Bleomycin results in increased cleavage of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein] 		CTD PMID:15371238 PMID:16317386 PMID:32278510 NCBI chr13:94,839,484...94,871,295
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:133,605,375...133,631,312
Ensembl chr 7:133,605,573...133,629,863 		JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236 		JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression EXP Bleomycin results in increased expression of PDLIM1 protein CTD PMID:25933445 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076 		JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression EXP Bleomycin results in increased expression of PDLIM5 protein CTD PMID:25933445 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275 		JBrowse link
G Pdxk pyridoxal kinase increases expression EXP Bleomycin results in increased expression of PDXK protein CTD PMID:25933445 NCBI chr20:10,210,276...10,232,314
Ensembl chr20:10,210,289...10,232,110 		JBrowse link
G Pecam1 platelet and endothelial cell adhesion molecule 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of PECAM1 protein] CTD PMID:30825431 NCBI chr10:91,590,521...91,652,279
Ensembl chr10:91,590,521...91,652,116 		JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein
Bleomycin results in decreased expression of PLAU mRNA; Bleomycin results in decreased expression of PLAU protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAU protein] 		CTD PMID:25648892 PMID:35716765 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plaur plasminogen activator, urokinase receptor decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of PLAUR mRNA; Bleomycin results in decreased expression of PLAUR protein
Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR mRNA]; Curcumin inhibits the reaction [Bleomycin results in decreased expression of PLAUR protein] 		CTD PMID:35716765 NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595 		JBrowse link
G Pml PML nuclear body scaffold multiple interactions
increases expression 		ISO arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 NCBI chr 8:67,523,164...67,557,801
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression EXP Bleomycin results in decreased expression of PNP protein CTD PMID:25933445 NCBI chr15:24,170,607...24,178,269
Ensembl chr15:24,170,602...24,203,986 		JBrowse link
G Podxl podocalyxin-like decreases expression EXP Bleomycin results in decreased expression of PODXL protein CTD PMID:25933445 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899 		JBrowse link
G Polb DNA polymerase beta decreases response to substance ISO POLB results in decreased susceptibility to Bleomycin CTD PMID:21251944 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases response to substance 		ISO PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]
PPARA protein results in decreased susceptibility to Bleomycin 		CTD PMID:16317386 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG protein
lenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]
Berberine inhibits the reaction [Bleomycin binds to PPARG protein] 		CTD PMID:19147827 PMID:27153807 PMID:29408570 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ppfia4 PTPRF interacting protein alpha 4 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PPFIA4 mRNA] CTD PMID:30825431 NCBI chr13:45,753,827...45,802,305
Ensembl chr13:45,753,827...45,802,261 		JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Bleomycin results in increased expression of PPIA protein CTD PMID:25933445 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601 		JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression EXP Bleomycin results in decreased expression of PRDX2 protein CTD PMID:25933445 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 NCBI chr13:76,062,082...76,072,631
Ensembl chr13:73,528,210...73,539,355 		JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein decreases expression EXP Bleomycin results in decreased expression of PRELP protein CTD PMID:25933445 NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270 		JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905 		JBrowse link
G Psme1 proteasome activator subunit 1 increases expression EXP Bleomycin results in increased expression of PSME1 protein CTD PMID:25933445 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890 		JBrowse link
G Psme2 proteasome activator subunit 2 decreases expression EXP Bleomycin results in decreased expression of PSME2 protein CTD PMID:25933445 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946 		JBrowse link
G Ptafr platelet-activating factor receptor multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of PTAFR mRNA] CTD PMID:30825431 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251 		JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP Bleomycin results in increased expression of PTBP1 protein CTD PMID:25933445 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397 		JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression 		ISO ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein]
Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein 		CTD PMID:29408570 NCBI chr 1:240,043,707...240,110,330
Ensembl chr 1:230,630,338...230,696,838 		JBrowse link
G Ptgdr prostaglandin D2 receptor increases expression ISO Bleomycin results in increased expression of PTGDR mRNA CTD PMID:20719937 NCBI chr15:17,360,304...17,367,679
Ensembl chr15:17,360,304...17,367,679 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA] 		CTD PMID:26526764 PMID:27704718 PMID:32828905 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Ptms parathymosin increases expression EXP Bleomycin results in increased expression of PTMS protein CTD PMID:25933445 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009 		JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAB1B protein CTD PMID:25933445 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
Ensembl chr  X:202,405,759...202,413,868 		JBrowse link
G Rac2 Rac family small GTPase 2 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of RAC2 mRNA] CTD PMID:30825431 NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720 		JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of RAD51AP1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of RAD51AP1 mRNA] 		CTD PMID:30825431 NCBI chr 4:159,759,454...159,772,473
Ensembl chr 4:159,759,459...159,772,524 		JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Bleomycin results in increased expression of RALB protein CTD PMID:25933445 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAP1B protein CTD PMID:25933445 NCBI chr 7:53,423,039...53,456,349
Ensembl chr 7:53,423,130...53,456,370 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
increases expression
decreases expression
increases phosphorylation
increases activity 		ISO
EXP 		Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of RELA mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of RELA protein modified form]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Bleomycin results in increased expression of RELA mRNA; Bleomycin results in increased expression of RELA protein; Bleomycin results in increased expression of RELA protein modified form
Bleomycin results in decreased expression of RELA mRNA
Bleomycin results in increased phosphorylation of RELA protein
Ephedrine inhibits the reaction [Bleomycin results in increased phosphorylation of RELA protein]; methyl caffeate inhibits the reaction [Bleomycin results in increased activity of RELA protein] 		CTD PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:28299617 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO Bleomycin results in decreased expression of RELB mRNA CTD PMID:29720568 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G Robo1 roundabout guidance receptor 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of ROBO1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ROBO1 mRNA] 		CTD PMID:30825431 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Rpl12 ribosomal protein L12 increases expression EXP Bleomycin results in increased expression of RPL12 protein CTD PMID:25933445 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642 		JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP Bleomycin results in increased expression of RPL13 protein CTD PMID:25933445 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
Ensembl chr 3:51,153,924...51,163,014 		JBrowse link
G Rpl4 ribosomal protein L4 increases expression EXP Bleomycin results in increased expression of RPL4 protein CTD PMID:25933445 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306 		JBrowse link
G Rpl5 ribosomal protein L5 increases expression EXP Bleomycin results in increased expression of RPL5 protein CTD PMID:25933445 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290 		JBrowse link
G Rpl6 ribosomal protein L6 affects expression EXP Bleomycin affects the expression of RPL6 protein CTD PMID:25933445 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921 		JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Bleomycin results in increased expression of RPS3A1 protein CTD PMID:25933445 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055 		JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Bleomycin results in increased expression of S100A11 protein CTD PMID:25933445 NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044 		JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression
multiple interactions 		EXP Bleomycin results in increased expression of S100A4 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein] 		CTD PMID:25933445 PMID:31706003 NCBI chr 2:178,388,529...178,390,838
Ensembl chr 2:176,091,804...176,093,254 		JBrowse link
G S100a6 S100 calcium binding protein A6 affects expression EXP Bleomycin affects the expression of S100A6 protein CTD PMID:25933445 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180 		JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Bleomycin results in increased expression of S100A8 protein CTD PMID:25933445 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein CTD PMID:29033951 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions
increases expression 		ISO S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] CTD PMID:29033951 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505 		JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 multiple interactions
affects response to substance 		ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] CTD PMID:29033951 NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795 		JBrowse link
G Scarna15 small Cajal body-specific RNA 15 affects expression EXP Bleomycin affects the expression of SCARNA15 mRNA CTD PMID:25933445 NCBI chr 1:135,484,620...135,484,683
Ensembl chr 1:135,484,559...135,484,685
Ensembl chr 1:135,484,559...135,484,685 		JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Bleomycin results in decreased expression of SCGB1A1 protein CTD PMID:25933445 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610 		JBrowse link
G Scp2 sterol carrier protein 2 increases expression EXP Bleomycin results in increased expression of SCP2 protein CTD PMID:25933445 NCBI chr 5:128,035,714...128,110,015
Ensembl chr 5:122,776,549...122,881,287 		JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression EXP Bleomycin results in increased expression of SCPEP1 protein CTD PMID:25933445 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850 		JBrowse link
G Scube3 signal peptide, CUB domain and EGF like domain containing 3 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SCUBE3 mRNA] CTD PMID:30825431 NCBI chr20:6,199,182...6,231,100
Ensembl chr20:6,199,182...6,228,584 		JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression EXP Bleomycin results in decreased expression of SEC14L3 protein CTD PMID:25933445 NCBI chr14:78,944,568...78,955,608
Ensembl chr14:78,912,750...78,956,099 		JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP Bleomycin results in decreased expression of SELENBP1 protein CTD PMID:25933445 NCBI chr 2:182,494,004...182,504,594
Ensembl chr 2:182,493,978...182,504,594 		JBrowse link
G Serpinb2 serpin family B member 2 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SERPINB2 mRNA] CTD PMID:30825431 NCBI chr13:23,537,312...23,551,823
Ensembl chr13:23,541,400...23,550,408 		JBrowse link
G Serpine1 serpin family E member 1 increases expression
decreases expression
multiple interactions 		ISO Bleomycin results in increased expression of SERPINE1 mRNA; Bleomycin results in increased expression of SERPINE1 protein
Bleomycin results in decreased expression of SERPINE1 protein
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein] 		CTD PMID:29175452 PMID:30825431 PMID:35716765 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657 		JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions
increases expression 		EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] CTD PMID:23656969 PMID:25933445 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801 		JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Bleomycin results in increased expression of SFRP1 mRNA CTD PMID:26345256 NCBI chr16:68,575,763...68,614,180
Ensembl chr16:68,575,763...68,614,286 		JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions
decreases expression
increases expression 		ISO
EXP 		[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]
Bleomycin results in decreased expression of SFTPA1 mRNA
Bleomycin results in increased expression of SFTPA1 protein 		CTD PMID:14617519 PMID:15782499 PMID:25933445 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685 		JBrowse link
G Sftpb surfactant protein B decreases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of SFTPB mRNA
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein 		CTD PMID:15782499 PMID:33647319 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436 		JBrowse link
G Sftpc surfactant protein C decreases expression EXP Bleomycin results in decreased expression of SFTPC mRNA; Bleomycin results in decreased expression of SFTPC protein CTD PMID:34425168 NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777 		JBrowse link
G Sftpd surfactant protein D increases expression
increases metabolic processing
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein
Bleomycin results in increased metabolism of SFTPD protein
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein] 		CTD PMID:11880309 PMID:25933445 PMID:26526764 PMID:33647319 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927 		JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein
resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein] 		CTD PMID:25707573 NCBI chr20:25,305,953...25,328,000
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Bleomycin results in increased expression of SLC12A1 mRNA CTD PMID:15808516 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899 		JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Bleomycin results in increased expression of SLC1A2 mRNA CTD PMID:15808516 NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression EXP Bleomycin results in decreased expression of SLC25A4 protein CTD PMID:25933445 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases expression EXP Bleomycin results in decreased expression of SLC25A5 protein CTD PMID:25933445 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967 		JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression EXP Bleomycin results in increased expression of SLC6A12 mRNA CTD PMID:15808516 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750 		JBrowse link
G Slc6a15 solute carrier family 6 member 15 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SLC6A15 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC6A15 mRNA] 		CTD PMID:30825431 NCBI chr 7:38,553,055...38,607,239
Ensembl chr 7:38,553,196...38,607,239 		JBrowse link
G Slc7a1 solute carrier family 7 member 1 decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SLC7A1 mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SLC7A1 mRNA] 		CTD PMID:30825431 NCBI chr12:6,628,288...6,703,849
Ensembl chr12:6,628,007...6,703,849 		JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 increases response to substance
multiple interactions 		ISO SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin
[SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA] 		CTD PMID:32828905 NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353 		JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression
multiple interactions 		ISO Bleomycin results in increased expression of SLPI mRNA; Bleomycin results in increased expression of SLPI protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of SLPI mRNA] 		CTD PMID:26345256 PMID:30825431 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453 		JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
increases expression 		ISO Bleomycin results in increased phosphorylation of SMAD2 protein
camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]
yupingfeng inhibits the reaction [Bleomycin results in increased expression of SMAD2 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein] 		CTD PMID:26599507 PMID:31884830 PMID:32032644 PMID:35187969 PMID:37898439 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases expression
increases phosphorylation 		EXP
ISO 		Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA]
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; MIR182 affects the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein] 		CTD PMID:26093215 PMID:27704718 PMID:31884830 PMID:32032644 PMID:35187969 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
G Smad7 SMAD family member 7 decreases expression
increases expression
multiple interactions 		EXP
ISO 		Bleomycin results in decreased expression of SMAD7 mRNA
Bleomycin results in increased expression of SMAD7 mRNA
MIR182 affects the reaction [Bleomycin results in decreased expression of SMAD7 protein]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] 		CTD PMID:26093215 PMID:29033951 PMID:31884830 NCBI chr18:71,263,508...71,291,849
Ensembl chr18:68,988,429...69,016,765 		JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases phosphorylation ISO Bleomycin results in increased phosphorylation of SMC1A protein CTD PMID:24933654 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056 		JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Bleomycin results in decreased expression of SMIM14 mRNA CTD PMID:33770205 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760 		JBrowse link
G Smtn smoothelin decreases expression
multiple interactions 		ISO Bleomycin results in decreased expression of SMTN mRNA
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of SMTN mRNA] 		CTD PMID:30825431 NCBI chr14:78,398,595...78,420,908
Ensembl chr14:78,397,778...78,420,886 		JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression EXP Bleomycin results in decreased expression of SNORA58 mRNA CTD PMID:25933445 NCBI chr 6:107,080,945...107,081,020
Ensembl chr 6:107,080,945...107,081,020 		JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Bleomycin results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:5,389,574...5,391,265
Ensembl chr10:4,882,560...4,884,383 		JBrowse link
G Sod1 superoxide dismutase 1 increases expression
multiple interactions
decreases expression
decreases activity 		ISO
EXP 		Bleomycin results in increased expression of SOD1 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]
Bleomycin results in decreased expression of SOD1 protein
Bleomycin results in decreased activity of SOD1 protein 		CTD PMID:8317554 PMID:25933445 PMID:30106319 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249 		JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases activity 		ISO
EXP 		Bleomycin results in increased expression of SOD2 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in decreased activity of SOD2 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein] 		CTD PMID:8317554 PMID:26768587 NCBI chr 1:50,043,323...50,050,168
Ensembl chr 1:47,636,528...47,645,189 		JBrowse link
G Sparc secreted protein acidic and cysteine rich increases response to substance ISO SPARC protein results in increased susceptibility to Bleomycin CTD PMID:19446018 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396 		JBrowse link
G Sparcl1 SPARC like 1 decreases expression EXP Bleomycin results in decreased expression of SPARCL1 protein CTD PMID:25933445 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865 		JBrowse link
G Spc25 SPC25 component of NDC80 kinetochore complex increases expression ISO Bleomycin results in increased expression of SPC25 mRNA CTD PMID:36087614 NCBI chr 3:53,930,013...53,988,940
Ensembl chr 3:53,975,704...53,988,959 		JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 PMID:29175452 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP Bleomycin results in decreased expression of SPTAN1 protein CTD PMID:25933445 NCBI chr 3:33,639,020...33,703,890
Ensembl chr 3:13,241,217...13,306,046 		JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Bleomycin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448 		JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP Bleomycin results in decreased expression of SSTR1 mRNA CTD PMID:15808516 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802 		JBrowse link
G Sstr2 somatostatin receptor 2 decreases expression EXP Bleomycin results in decreased expression of SSTR2 mRNA CTD PMID:15808516 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351 		JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression EXP Bleomycin results in decreased expression of SSTR3 mRNA CTD PMID:15808516 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769 		JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ST14 protein CTD PMID:26599507 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517 		JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Bleomycin results in decreased expression of ST3GAL5 mRNA CTD PMID:33770205 NCBI chr 4:104,134,613...104,192,558
Ensembl chr 4:104,134,613...104,192,558 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression 		ISO honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
decreases response to substance 		ISO STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
STAT6 gene mutant form results in decreased susceptibility to Bleomycin 		CTD PMID:15322207 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495 		JBrowse link
G Stk11 serine/threonine kinase 11 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of STK11 protein
Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein] 		CTD PMID:31302203 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315 		JBrowse link
G Stmn1 stathmin 1 increases expression EXP Bleomycin results in increased expression of STMN1 protein CTD PMID:25933445 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154 		JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b increases expression EXP Bleomycin results in increased expression of SV2B mRNA CTD PMID:15808516 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479 		JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression EXP Bleomycin results in decreased expression of TACR2 mRNA CTD PMID:15808516 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446 		JBrowse link
G Tagln transgelin increases expression EXP Bleomycin results in increased expression of TAGLN protein CTD PMID:25933445 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668 		JBrowse link
G Tagln2 transgelin 2 increases expression EXP Bleomycin results in increased expression of TAGLN2 protein CTD PMID:25933445 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972 		JBrowse link
G Taldo1 transaldolase 1 decreases expression EXP Bleomycin results in decreased expression of TALDO1 protein CTD PMID:25933445 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974 		JBrowse link
G Tapbp TAP binding protein affects response to substance ISO TAPBP protein affects the susceptibility to Bleomycin CTD PMID:38992170 NCBI chr20:4,956,937...4,966,191
Ensembl chr20:4,956,937...4,966,181 		JBrowse link
G Tbx21 T-box transcription factor 21 increases expression ISO Bleomycin results in increased expression of TBX21 mRNA CTD PMID:29033951 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831 		JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B decreases expression ISO Bleomycin results in decreased expression of TENT4B mRNA CTD PMID:33770205 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537 		JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tf transferrin increases expression EXP Bleomycin results in increased expression of TF protein CTD PMID:25933445 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases secretion
increases expression 		ISO
EXP 		(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 5-hydroxydecanoic acid inhibits the reaction [baicalein inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; 5-hydroxydecanoic acid inhibits the reaction [Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of TGFB1 mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of TGFB1 mRNA; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Diazoxide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; MIR182 affects the reaction [Bleomycin results in increased expression of TGFB1 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; pachymic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
Bleomycin results in increased secretion of TGFB1 protein
Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein
yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein] 		CTD PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 More... NCBI chr 1:90,324,312...90,340,627
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression EXP Bleomycin results in decreased expression of TGFB1I1 protein CTD PMID:25933445 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] CTD PMID:28434932 NCBI chr13:100,691,540...100,793,227
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TGFB3 mRNA
CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] 		CTD PMID:28434932 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564 		JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression 		ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] 		CTD PMID:28434932 PMID:28726637 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] CTD PMID:28434932 NCBI chr 8:124,672,677...124,761,741
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tgif2 TGFB-induced factor homeobox 2 increases expression ISO Bleomycin results in increased expression of TGIF2 mRNA CTD PMID:36087614 NCBI chr 3:145,333,152...145,348,599
Ensembl chr 3:145,333,418...145,348,596
Ensembl chr17:145,333,418...145,348,596 		JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Bleomycin results in increased expression of THBS1 mRNA CTD PMID:29720568 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of THBS2 protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of THBS2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of THBS2 protein] 		CTD PMID:30825431 NCBI chr 1:55,670,394...55,699,789
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression ISO Bleomycin results in decreased expression of THOP1 protein CTD PMID:29733421 NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275 		JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Bleomycin results in decreased expression of THRB mRNA CTD PMID:15808516 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916 		JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein
Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein] 		CTD PMID:26345256 PMID:28300665 PMID:32032644 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664 		JBrowse link
G Tlr1 toll-like receptor 1 decreases expression ISO Bleomycin results in decreased expression of TLR1 mRNA CTD PMID:29720568 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125 		JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 decreases expression ISO Bleomycin results in decreased expression of TMCC3 mRNA CTD PMID:33770205 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926 		JBrowse link
G Tmem250 transmembrane protein 250 increases expression ISO Bleomycin results in increased expression of TMEM250 mRNA CTD PMID:33770205 NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349 		JBrowse link
G Tmem87a transmembrane protein 87A increases expression ISO Bleomycin results in increased expression of TMEM87A mRNA CTD PMID:33770205 NCBI chr 3:107,307,726...107,353,571
Ensembl chr 3:107,307,726...107,353,551 		JBrowse link
G Tnc tenascin C increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of TNC protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TNC protein] 		CTD PMID:26345256 PMID:30825431 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
affects response to substance 		ISO
EXP 		[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ephedrine inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; yupingfeng inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of TNF protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein]
1-hydroxyalantolactone inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein; Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein]
Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein 		CTD PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases response to substance
increases expression 		ISO TNFRSF1A results in increased susceptibility to Bleomycin
Bleomycin results in increased expression of TNFRSF1A mRNA 		CTD PMID:12003776 PMID:36087614 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression
increases response to substance 		EXP
ISO 		Bleomycin results in increased expression of TNFRSF1B protein
TNFRSF1B results in increased susceptibility to Bleomycin 		CTD PMID:12003776 PMID:15371238 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Bleomycin results in decreased expression of TNFSF11 mRNA CTD PMID:29720568 NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445 		JBrowse link
G Tnfsf4 TNF superfamily member 4 increases expression ISO Bleomycin results in increased expression of TNFSF4 mRNA CTD PMID:36087614 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788 		JBrowse link
G Tp53 tumor protein p53 increases expression
increases response to substance
increases phosphorylation
multiple interactions 		ISO Bleomycin results in increased expression of TRP53 protein
TP53 protein results in increased susceptibility to Bleomycin
Bleomycin results in increased phosphorylation of TP53 protein
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA] 		CTD PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 NCBI chr10:54,798,871...54,810,300
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Bleomycin results in increased expression of TPM1 protein CTD PMID:25933445 NCBI chr 8:76,516,654...76,543,661
Ensembl chr 8:67,635,479...67,662,802 		JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Bleomycin results in increased expression of TPM3 protein CTD PMID:25933445 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013 		JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984 		JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression EXP Bleomycin results in decreased expression of TPPP3 protein CTD PMID:25933445 NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression
increases expression 		EXP
ISO 		Bleomycin results in decreased expression of TRAF2 protein
Bleomycin results in increased expression of TRAF2 mRNA 		CTD PMID:15371238 PMID:36087614 NCBI chr 3:28,740,098...28,764,752
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] CTD PMID:26520185 NCBI chr20:44,565,992...44,609,240
Ensembl chr20:43,011,450...43,054,667 		JBrowse link
G Trim28 tripartite motif-containing 28 increases phosphorylation ISO Bleomycin results in increased phosphorylation of TRIM28 protein CTD PMID:24933654 NCBI chr 1:82,724,842...82,731,566
Ensembl chr 1:73,652,709...73,659,380 		JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] CTD PMID:26600069 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181 		JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538 		JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Bleomycin results in decreased expression of TUBA1C protein CTD PMID:25933445 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP
ISO 		Bleomycin results in decreased expression of TUBB2A protein
Bleomycin results in decreased expression of TUBB2A mRNA 		CTD PMID:25933445 PMID:33770205 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Bleomycin results in decreased expression of TUBB4B protein CTD PMID:25933445 NCBI chr 3:8,037,838...8,040,294
Ensembl chr 3:8,037,799...8,040,296 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 increases expression ISO Bleomycin results in increased expression of TWIST1 protein CTD PMID:37126650 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
G Tymp thymidine phosphorylase increases expression
multiple interactions 		ISO Bleomycin results in increased expression of TYMP protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of TYMP protein] 		CTD PMID:30825431 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874 		JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO Bleomycin results in decreased expression of UGCG mRNA CTD PMID:33770205 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393 		JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression
multiple interactions 		ISO Bleomycin results in increased expression of ULK1 protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form] 		CTD PMID:31302203 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966 		JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression EXP Bleomycin results in decreased expression of UQCRC1 protein CTD PMID:25933445 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 multiple interactions
increases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VAV1 mRNA] CTD PMID:30825431 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Vcl vinculin decreases expression EXP Bleomycin results in decreased expression of VCL protein CTD PMID:25933445 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606 		JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Bleomycin results in increased expression of VEGFA mRNA CTD PMID:26093215 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
G Vegfb vascular endothelial growth factor B increases expression
multiple interactions 		ISO Bleomycin results in increased expression of VEGFB protein
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of VEGFB protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of VEGFB protein] 		CTD PMID:30825431 NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944 		JBrowse link
G Vim vimentin increases expression
decreases expression
affects expression
multiple interactions 		EXP
ISO 		Bleomycin results in increased expression of VIM protein
Bleomycin results in decreased expression of VIM mRNA
Bleomycin affects the expression of VIM protein
Bleomycin results in increased expression of VIM mRNA; Bleomycin results in increased expression of VIM protein
geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; geranylgeranylacetone inhibits the reaction [Bleomycin results in increased expression of VIM protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of VIM protein]; MKLN1 mRNA alternative form affects the reaction [Bleomycin results in increased expression of VIM protein]
Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM mRNA]; Ephedrine inhibits the reaction [Bleomycin results in increased expression of VIM protein] 		CTD PMID:25933445 PMID:34425168 PMID:35267148 PMID:35472619 PMID:37126650 More... NCBI chr17:81,577,261...81,585,746
Ensembl chr17:76,668,647...76,677,187 		JBrowse link
G Vwf von Willebrand factor multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of VWF protein] CTD PMID:30825431 NCBI chr 4:158,360,152...158,491,539
Ensembl chr 4:158,360,152...158,491,539 		JBrowse link
G Wif1 Wnt inhibitory factor 1 multiple interactions
decreases expression 		ISO Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of WIF1 mRNA] CTD PMID:30825431 NCBI chr 7:56,548,060...56,618,364
Ensembl chr 7:56,548,053...56,618,360 		JBrowse link
G Wnt1 Wnt family member 1 increases expression ISO Bleomycin results in increased expression of WNT1 mRNA CTD PMID:36087614 NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651 		JBrowse link
G Wnt10a Wnt family member 10A increases expression ISO Bleomycin results in increased expression of WNT10A mRNA CTD PMID:36087614 NCBI chr 9:76,349,931...76,362,400
Ensembl chr 9:76,349,931...76,362,400 		JBrowse link
G Wnt9a Wnt family member 9A increases expression ISO Bleomycin results in increased expression of WNT9A mRNA CTD PMID:36087614 NCBI chr10:44,094,140...44,121,134
Ensembl chr10:44,094,140...44,121,133 		JBrowse link
G Xrcc1 X-ray repair cross complementing 1 affects response to substance
decreases response to substance 		ISO XRCC1 gene polymorphism affects the susceptibility to Bleomycin
XRCC1 results in decreased susceptibility to Bleomycin 		CTD PMID:12082022 PMID:20705543 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701 		JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Bleomycin CTD PMID:12384553 NCBI chr 9:73,955,216...74,044,020
Ensembl chr 9:73,955,216...74,044,018 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase decreases expression ISO Bleomycin results in decreased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837 		JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression EXP Bleomycin results in decreased expression of YWHAB protein CTD PMID:25933445 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105 		JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO Bleomycin results in increased expression of ZFX mRNA CTD PMID:33770205 NCBI chr  X:58,804,690...58,853,155
Ensembl chr  X:58,804,691...58,853,265 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 20845
    role 20805
      biological role 20803
        antimicrobial agent 18553
          bleomycin 739
            bleomycin A2 662
Path 2
Term Annotations click to browse term
  CHEBI ontology 20845
    subatomic particle 20843
      composite particle 20843
        hadron 20843
          baryon 20843
            nucleon 20843
              atomic nucleus 20843
                atom 20843
                  main group element atom 20766
                    p-block element atom 20766
                      carbon group element atom 20699
                        carbon atom 20693
                          organic molecular entity 20693
                            heteroorganic entity 20202
                              organochalcogen compound 19890
                                organooxygen compound 19792
                                  carbon oxoacid 19137
                                    carboxylic acid 19134
                                      carboacyl group 18064
                                        univalent carboacyl group 18064
                                          carbamoyl group 17899
                                            carboxamide 17899
                                              peptide 11657
                                                peptide antibiotic 2753
                                                  chelate-forming peptide 739
                                                    bleomycin 739
                                                      bleomycin A2 662
paths to the root