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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:peptide antibiotic
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actinomycin D term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb1a ATP binding cassette subfamily B member 1A decreases response to substance
multiple interactions
ISO
EXP
ABCB1 protein results in decreased susceptibility to Dactinomycin
Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1A mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Dactinomycin inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]
Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]; Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]; Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]; Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA]
CTD PMID:1967174, PMID:11455017, PMID:15725475, PMID:18474546, PMID:19813763, PMID:20410605, PMID:30830211 NCBI chr 4:22,339,829...22,517,642
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcb1b ATP-binding cassette, subfamily B (MDR/TAP), member 1B multiple interactions EXP Dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1B mRNA] CTD PMID:20410605 NCBI chr 4:22,225,123...22,307,577
Ensembl chr 4:22,133,521...22,425,515
JBrowse link
G Abcc1 ATP binding cassette subfamily C member 1 decreases response to substance ISO
EXP
ABCC1 protein results in decreased susceptibility to Dactinomycin CTD PMID:11455017, PMID:12067707 NCBI chr10:549,537...672,235
Ensembl chr10:549,883...672,196
JBrowse link
G Abcc2 ATP binding cassette subfamily C member 2 decreases response to substance
multiple interactions
EXP
ISO
ABCC2 protein results in decreased susceptibility to Dactinomycin
Dactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA]
Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA]
CTD PMID:11408547, PMID:11455017, PMID:26049102 NCBI chr 1:263,554,426...263,612,556
Ensembl chr 1:263,554,453...263,613,252
JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 multiple interactions ISO Dactinomycin inhibits the reaction [Daunorubicin results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [Doxorubicin results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [Mitoxantrone results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [SHH protein alternative form results in increased expression of ABCG2 protein]; Dactinomycin inhibits the reaction [Sulfasalazine results in increased expression of ABCG2 mRNA] CTD PMID:20019844, PMID:21625222 NCBI chr 4:88,765,441...88,890,268
Ensembl chr 4:88,832,178...88,890,621
JBrowse link
G Abhd3 abhydrolase domain containing 3, phospholipase increases expression ISO Dactinomycin results in increased expression of ABHD3 mRNA CTD PMID:21527772 NCBI chr18:1,892,413...1,946,840
Ensembl chr18:1,892,413...1,946,840
JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP Dactinomycin inhibits the reaction [Aldosterone results in increased activity of ACE protein]; Dactinomycin inhibits the reaction [Aldosterone results in increased expression of ACE mRNA] CTD PMID:15932931 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Acsl6 acyl-CoA synthetase long-chain family member 6 multiple interactions EXP Dactinomycin inhibits the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of ACSL6 mRNA] CTD PMID:10585473 NCBI chr10:39,654,771...39,717,592
Ensembl chr10:39,655,455...39,719,312
JBrowse link
G Adam9 ADAM metallopeptidase domain 9 multiple interactions ISO Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] CTD PMID:17018608 NCBI chr16:71,810,377...71,887,926
Ensembl chr16:71,810,377...71,887,926
JBrowse link
G Adrb2 adrenoceptor beta 2 multiple interactions ISO Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of ADRB2 protein]; Dactinomycin inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA]; Dactinomycin inhibits the reaction [Formoterol Fumarate affects the expression of ADRB2 mRNA] CTD PMID:22483689, PMID:24705868 NCBI chr18:57,513,792...57,515,834
Ensembl chr18:57,513,793...57,515,834
JBrowse link
G Agt angiotensinogen multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA]
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA]; Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA]; Dactinomycin promotes the reaction [Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]]; Dactinomycin promotes the reaction [Valsartan inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]]
CTD PMID:16705055, PMID:17214612, PMID:19292980, PMID:23288202 NCBI chr19:57,321,594...57,333,460
Ensembl chr19:57,321,640...57,333,433
JBrowse link
G Ahr aryl hydrocarbon receptor multiple interactions ISO Dactinomycin inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA]
ARNT protein promotes the reaction [Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]
CTD PMID:9145908, PMID:16226227, PMID:25637755 NCBI chr 6:54,963,990...55,001,806
Ensembl chr 6:54,963,990...55,001,464
JBrowse link
G Aicda activation-induced cytidine deaminase multiple interactions ISO [Dactinomycin co-treated with Alpha-Amanitin] inhibits the reaction [Estradiol results in increased expression of AICDA mRNA] CTD PMID:19139166 NCBI chr 4:155,359,909...155,371,104
Ensembl chr 4:155,359,921...155,369,671
JBrowse link
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO [Dactinomycin co-treated with TNFSF10 protein] results in increased expression of AIFM1 protein CTD PMID:17707539 NCBI chr  X:135,304,063...135,343,062
Ensembl chr  X:135,304,066...135,343,087
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]
CTD PMID:14640974 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alpi alkaline phosphatase, intestinal multiple interactions EXP Dactinomycin inhibits the reaction [Fish Oils results in increased activity of ALPI protein] CTD PMID:15599000 NCBI chr 9:94,197,616...94,201,910
Ensembl chr 9:94,197,618...94,201,084
JBrowse link
G Alx3 ALX homeobox 3 multiple interactions EXP Dactinomycin inhibits the reaction [Folic Acid results in increased expression of ALX3 mRNA] CTD PMID:20534379 NCBI chr 2:210,376,510...210,386,928
Ensembl chr 2:210,381,829...210,386,928
JBrowse link
G Aoc1 amine oxidase, copper containing 1 multiple interactions EXP Dactinomycin inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Terbutaline results in increased activity of AOC1 protein] CTD PMID:2860926, PMID:6218830 NCBI chr 4:78,496,043...78,515,582
Ensembl chr 4:78,496,043...78,515,584
JBrowse link
G Aqp1 aquaporin 1 multiple interactions ISO Dactinomycin inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA] CTD PMID:22415096 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta increases expression ISO Dactinomycin results in increased expression of ARHGDIB mRNA CTD PMID:21527772 NCBI chr 4:170,913,920...170,932,789
Ensembl chr 4:170,913,923...170,932,618
JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator multiple interactions ISO ARNT protein promotes the reaction [Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]] CTD PMID:16226227 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179
JBrowse link
G Atf4 activating transcription factor 4 multiple interactions ISO Dactinomycin inhibits the reaction [Bortezomib results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Bortezomib results in increased expression of ATF4 protein]; Dactinomycin inhibits the reaction [Fenretinide results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Fenretinide results in increased expression of ATF4 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein] CTD PMID:20022965 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO Dactinomycin inhibits the reaction [Ethanol results in increased expression of ATG7 protein] CTD PMID:24095927 NCBI chr 4:146,570,113...146,777,093
Ensembl chr 4:146,598,413...146,777,124
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions ISO Dactinomycin results in decreased expression of and results in increased phosphorylation of ATM protein CTD PMID:31226288 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Avp arginine vasopressin multiple interactions EXP Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein] CTD PMID:11102496 NCBI chr 3:123,117,482...123,119,460
Ensembl chr 3:123,117,492...123,119,460
JBrowse link
G Axl Axl receptor tyrosine kinase increases expression ISO Dactinomycin results in increased expression of AXL mRNA CTD PMID:21527772 NCBI chr 1:82,550,892...82,580,761
Ensembl chr 1:82,549,420...82,580,761
JBrowse link
G Bag3 BAG cochaperone 3 multiple interactions ISO Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of BAG3 mRNA] CTD PMID:22020323 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191
JBrowse link
G Bak1 BCL2-antagonist/killer 1 multiple interactions EXP
ISO
Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAK1 mRNA]
Dactinomycin promotes the reaction [BAK1 protein binds to BAK1 protein]
CTD PMID:21281706, PMID:26670606 NCBI chr20:5,609,620...5,618,899
Ensembl chr20:5,609,625...5,618,260
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression
multiple interactions
ISO
EXP
Dactinomycin results in increased expression of BAX mRNA; Dactinomycin results in increased expression of BAX protein
Dactinomycin promotes the reaction [BAX protein binds to BAX protein]
Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAX mRNA]
Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]]
CTD PMID:10760829, PMID:12927789, PMID:21281706, PMID:21527772, PMID:26670606 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bbc3 Bcl-2 binding component 3 increases expression ISO Dactinomycin results in increased expression of BBC3 mRNA; Dactinomycin results in increased expression of BBC3 protein CTD PMID:17581298 NCBI chr 1:78,261,491...78,267,802 JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO BCL2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; Dactinomycin inhibits the reaction [IL1B results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of BCL2 protein]; Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]]
Dactinomycin results in decreased expression of BCL2 mRNA; Dactinomycin results in decreased expression of BCL2 protein
CTD PMID:11726273, PMID:11880364, PMID:12927789, PMID:16492401, PMID:17581298 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl2a1 BCL2-related protein A1 multiple interactions ISO BCL2A1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 8:96,551,424...96,559,527
Ensembl chr 8:96,551,245...96,559,483
JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression
multiple interactions
increases expression
ISO Dactinomycin results in decreased expression of BCL2L1 protein
Dexamethasone inhibits the reaction [Dactinomycin results in increased expression of BCL2L1 protein]
Dactinomycin results in increased expression of BCL2L1 protein; Dactinomycin results in increased expression of BCL2L1 protein alternative form
CTD PMID:9326359, PMID:12430140, PMID:15592511 NCBI chr 3:148,259,594...148,314,191
Ensembl chr 3:148,259,596...148,313,810
JBrowse link
G Bcl2l11 BCL2 like 11 multiple interactions ISO Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 mRNA] CTD PMID:16166651 NCBI chr 3:120,726,906...120,764,192
Ensembl chr 3:120,726,906...120,764,192
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions
decreases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of BDNF mRNA]
Dactinomycin results in decreased expression of BDNF mRNA
CTD PMID:22982731 NCBI chr 3:100,768,637...100,819,216
Ensembl chr 3:100,768,637...100,819,210
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Dactinomycin inhibits the reaction [Ethanol results in increased expression of BECN1 protein] CTD PMID:24095927 NCBI chr10:89,209,944...89,225,297
Ensembl chr10:89,209,940...89,225,297
JBrowse link
G Bid BH3 interacting domain death agonist multiple interactions ISO Dactinomycin inhibits the reaction [vorinostat results in increased cleavage of BID protein]
Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of BID mRNA]
CTD PMID:11535817, PMID:16166651 NCBI chr 4:153,439,812...153,465,247
Ensembl chr 4:153,442,218...153,465,203
JBrowse link
G Birc3 baculoviral IAP repeat-containing 3 multiple interactions ISO BIRC3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 8:6,048,590...6,076,828
Ensembl chr 8:6,048,969...6,076,598
JBrowse link
G Bnip3 BCL2 interacting protein 3 multiple interactions ISO [Dactinomycin co-treated with TNF protein] results in increased expression of BNIP3 mRNA; Dactinomycin inhibits the reaction [Ethanol results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] CTD PMID:11592958, PMID:19442826, PMID:24095927 NCBI chr 1:211,248,098...211,265,282
Ensembl chr 1:211,248,098...211,265,282
JBrowse link
G Bsdc1 BSD domain containing 1 increases expression ISO Dactinomycin results in increased expression of BSDC1 mRNA CTD PMID:21527772 NCBI chr 5:147,661,618...147,689,766
Ensembl chr 5:147,661,618...147,689,759
JBrowse link
G C1qbp complement C1q binding protein decreases response to substance ISO C1QBP protein results in decreased susceptibility to Dactinomycin CTD PMID:25354864 NCBI chr10:57,613,876...57,618,527
Ensembl chr10:57,613,879...57,618,527
JBrowse link
G Cacna1g calcium voltage-gated channel subunit alpha1 G multiple interactions EXP Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA] CTD PMID:19292980 NCBI chr10:82,129,071...82,197,828
Ensembl chr10:82,129,506...82,197,848
JBrowse link
G Cacna1h calcium voltage-gated channel subunit alpha1 H multiple interactions EXP Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA] CTD PMID:19292980 NCBI chr10:14,730,932...14,789,201
Ensembl chr10:14,730,941...14,788,617
JBrowse link
G Casp2 caspase 2 increases cleavage ISO Dactinomycin results in increased cleavage of CASP2 protein CTD PMID:10663630 NCBI chr 4:71,652,358...71,670,228
Ensembl chr 4:71,652,354...71,670,239
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
decreases expression
ISO
EXP
[TNF co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP3 protein; Dactinomycin inhibits the reaction [Biological Products results in increased expression of CASP3 mRNA]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP3 protein]
Dactinomycin results in increased cleavage of and results in increased activity of CASP3 protein
[Dactinomycin co-treated with TNF protein] results in increased activity of CASP3 protein
Dactinomycin results in increased activity of CASP3 protein
Dactinomycin results in decreased expression of CASP3 mRNA
CTD PMID:10663630, PMID:16001973, PMID:16492401, PMID:21496118, PMID:22654482, PMID:23300732, PMID:26670606 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp7 caspase 7 multiple interactions
decreases expression
ISO [Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP7 protein; [TNF co-treated with Dactinomycin] results in increased activity of CASP7 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP7 protein; Dactinomycin promotes the reaction [TNF results in increased activity of CASP7 protein]
Dactinomycin results in decreased expression of CASP7 mRNA
CTD PMID:16001973, PMID:16492401, PMID:17707539, PMID:21496118 NCBI chr 1:277,190,557...277,242,779
Ensembl chr 1:277,190,964...277,242,774
JBrowse link
G Casp8 caspase 8 decreases expression ISO Dactinomycin results in decreased expression of CASP8 mRNA CTD PMID:16001973 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases cleavage
ISO [Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP9 protein
Dactinomycin results in increased cleavage of CASP9 protein
CTD PMID:17707539, PMID:26670606 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cav1 caveolin 1 multiple interactions ISO Dactinomycin inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] CTD PMID:15314095 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 multiple interactions ISO Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA] CTD PMID:15531761 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 multiple interactions ISO Dactinomycin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] CTD PMID:15531761, PMID:16705055 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccn4 cellular communication network factor 4 multiple interactions ISO Dactinomycin inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA] CTD PMID:19238344 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ccna2 cyclin A2 multiple interactions EXP Dactinomycin inhibits the reaction [Homocysteine results in increased expression of CCNA2 mRNA] CTD PMID:8550827 NCBI chr 2:123,274,727...123,282,266
Ensembl chr 2:123,275,881...123,282,214
JBrowse link
G Ccnd1 cyclin D1 decreases stability ISO Dactinomycin results in decreased stability of CCND1 mRNA CTD PMID:15610522 NCBI chr 1:218,090,750...218,100,447
Ensembl chr 1:218,090,750...218,100,325
JBrowse link
G Cd1d1 CD1d1 molecule multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of CD1D mRNA] CTD PMID:17392484 NCBI chr 2:186,330,298...186,333,805
Ensembl chr 2:186,330,298...186,333,805
JBrowse link
G Cd28 Cd28 molecule multiple interactions ISO Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein] CTD PMID:11465111 NCBI chr 9:67,546,408...67,573,858
Ensembl chr 9:67,546,408...67,571,871
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions
decreases expression
ISO 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Dactinomycin results in increased expression of and affects the localization of CDKN1A protein]; Dactinomycin results in increased expression of and affects the localization of CDKN1A protein
Dactinomycin results in decreased expression of CDKN1A protein
CTD PMID:12807743, PMID:14601052 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta decreases expression ISO Dactinomycin results in decreased expression of CEBPB mRNA CTD PMID:16001973 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Cel carboxyl ester lipase increases expression ISO Dactinomycin results in increased expression of CEL mRNA CTD PMID:21527772 NCBI chr 3:7,134,021...7,141,522
Ensembl chr 3:7,134,021...7,141,522
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator decreases expression ISO Dactinomycin results in decreased expression of CFLAR protein CTD PMID:11234897, PMID:14601052 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Dactinomycin inhibits the reaction [Estradiol results in increased expression of CKB protein]; Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of CKB protein] CTD PMID:7839363 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clmn calmin multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of CLMN mRNA] CTD PMID:16688769 NCBI chr 6:128,473,592...128,567,267
Ensembl chr 6:128,473,570...128,567,198
JBrowse link
G Cnmd chondromodulin multiple interactions ISO Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein] CTD PMID:19525446 NCBI chr15:61,923,291...61,947,840
Ensembl chr15:61,923,299...61,947,764
JBrowse link
G Cnr1 cannabinoid receptor 1 multiple interactions ISO Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR1 mRNA] CTD PMID:21525939 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO Dactinomycin inhibits the reaction [gemcitabine results in increased expression of CNR2 mRNA] CTD PMID:21525939 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]
Dactinomycin results in decreased expression of COL1A1 mRNA
CTD PMID:11216681, PMID:18253093 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain multiple interactions EXP Dactinomycin inhibits the reaction [LEP protein results in increased expression of COL1A2 mRNA] CTD PMID:12704794 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 increases expression ISO Dactinomycin results in increased expression of CRABP2 mRNA CTD PMID:21527772 NCBI chr 2:187,322,416...187,326,794
Ensembl chr 2:184,882,969...184,883,505
JBrowse link
G Csf2 colony stimulating factor 2 multiple interactions ISO Dactinomycin inhibits the reaction [Reactive Oxygen Species results in increased expression of CSF2 protein]
Dactinomycin inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Dactinomycin inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein]
CTD PMID:9606035, PMID:10645887, PMID:11752025 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Ctf1 cardiotrophin 1 multiple interactions EXP Dactinomycin promotes the reaction [Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]]; Dactinomycin promotes the reaction [Valsartan inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]] CTD PMID:23288202 NCBI chr 1:199,162,319...199,168,296
Ensembl chr 1:199,163,086...199,168,296
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CYCS mRNA] CTD PMID:21281706 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Cygb cytoglobin multiple interactions ISO Dactinomycin inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] CTD PMID:25781201 NCBI chr10:105,618,325...105,628,091
Ensembl chr10:105,618,326...105,628,091
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [chromium trioxide results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [SB 203580 results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tetrandrine results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tetrandrine results in increased expression of CYP1A1 protein]; Dactinomycin promotes the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Dactinomycin promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA]
Dactinomycin results in decreased expression of CYP1A1 mRNA
Dactinomycin inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [afimoxifene results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [harman results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Itraconazole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Sunitinib results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A1 mRNA]
CTD PMID:1934297, PMID:10359656, PMID:11577022, PMID:11752201, PMID:16093525, PMID:17283379, PMID:17606337, PMID:19901195, PMID:20187624, PMID:20732341, PMID:21262253, PMID:21732638, PMID:23288144, PMID:26318284, PMID:26640276, PMID:31470059 NCBI chr 8:62,472,087...62,478,122
Ensembl chr 8:62,472,095...62,478,147
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO Dactinomycin inhibits the reaction [15,16-dihydrotanshinone I results in increased expression of CYP1A2 mRNA]; Dactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]; Dactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA] CTD PMID:21262253 NCBI chr 8:62,451,360...62,458,244
Ensembl chr 8:62,451,329...62,458,301
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA]
Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein]
Dactinomycin results in decreased expression of CYP1B1 mRNA
Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA]
CTD PMID:11577022, PMID:11752201, PMID:21867498 NCBI chr 6:2,308,179...2,316,739
Ensembl chr 6:2,307,808...2,316,722
JBrowse link
G Cyp2a3 cytochrome P450, family 2, subfamily a, polypeptide 3 multiple interactions
increases stability
ISO Dactinomycin affects the reaction [HNRNPA1 protein binds to CYP2A5 mRNA]; Dactinomycin inhibits the reaction [Cyclic AMP results in increased expression of CYP2A5 mRNA]; Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP2A5 mRNA]
Dactinomycin results in increased stability of CYP2A5 mRNA
CTD PMID:12754101 NCBI chr 1:83,653,248...83,662,118
Ensembl chr 1:83,653,234...83,766,484
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 multiple interactions ISO Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA] CTD PMID:9007836 NCBI chr 7:99,142,431...99,183,540
Ensembl chr 7:99,142,450...99,181,783
JBrowse link
G Cyp2f4 cytochrome P450, family 2, subfamily f, polypeptide 4 multiple interactions ISO Dactinomycin inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] CTD PMID:20187624 NCBI chr 1:83,933,974...83,947,804
Ensembl chr 1:83,933,942...83,947,821
JBrowse link
G Cyp2s1 cytochrome P450, family 2, subfamily s, polypeptide 1 multiple interactions ISO Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2S1 mRNA] CTD PMID:17277313 NCBI chr 1:82,595,211...82,610,350
Ensembl chr 1:82,595,211...82,610,350
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions EXP Dactinomycin inhibits the reaction [Methylcholanthrene results in increased expression of CYP3A2 mRNA]; Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP3A2 mRNA]; Dactinomycin inhibits the reaction [pyridine results in increased expression of CYP3A2 mRNA] CTD PMID:11181506 NCBI chr12:11,641,500...11,677,818
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a23-3a1 cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 multiple interactions EXP Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP3A23-3A1 mRNA]; Dactinomycin inhibits the reaction [pyridine results in increased expression of CYP3A23-3A1 mRNA] CTD PMID:11181506 NCBI chr12:11,053,888...11,082,742
Ensembl chr12:11,655,402...11,733,136
JBrowse link
G Cyp3a9 cytochrome P450, family 3, subfamily a, polypeptide 9 multiple interactions ISO Dactinomycin inhibits the reaction [U 0126 results in increased expression of CYP3A5 mRNA] CTD PMID:24819614 NCBI chr12:19,074,288...19,114,491
Ensembl chr12:19,074,583...19,114,399
JBrowse link
G Ddah2 dimethylarginine dimethylaminohydrolase 2 multiple interactions ISO Dactinomycin inhibits the reaction [Nebivolol results in increased expression of DDAH2 mRNA] CTD PMID:17977009 NCBI chr20:5,049,260...5,052,573
Ensembl chr20:5,049,496...5,052,585
JBrowse link
G Dio3 iodothyronine deiodinase 3 multiple interactions EXP Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] CTD PMID:18420745 NCBI chr 6:134,627,278...134,629,139
Ensembl chr 6:134,627,278...134,629,138
JBrowse link
G Dpysl4 dihydropyrimidinase-like 4 increases expression ISO Dactinomycin results in increased expression of DPYSL4 mRNA CTD PMID:21527772 NCBI chr 1:211,423,022...211,438,533
Ensembl chr 1:211,423,022...211,438,531
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO Dactinomycin inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] CTD PMID:22483689 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ednra endothelin receptor type A multiple interactions EXP [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRA mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRA protein] CTD PMID:20561571 NCBI chr19:33,928,356...33,991,703
Ensembl chr19:33,928,356...33,991,703
JBrowse link
G Ednrb endothelin receptor type B multiple interactions EXP Dactinomycin inhibits the reaction [Cyclosporine results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Smoke analog results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA] CTD PMID:20561571, PMID:20716444, PMID:22207076, PMID:25772258 NCBI chr15:88,004,775...88,036,354
Ensembl chr15:88,006,977...88,036,354
JBrowse link
G Efnb2 ephrin B2 multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of EFNB2 mRNA] CTD PMID:16688769 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Egf epidermal growth factor multiple interactions EXP Dactinomycin inhibits the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA] CTD PMID:12632255 NCBI chr 2:68,820,616...68,895,537 JBrowse link
G Egfr epidermal growth factor receptor multiple interactions EXP Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein]; Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] CTD PMID:8888411 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
G Egr1 early growth response 1 multiple interactions EXP Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA] CTD PMID:1717835 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Elovl3 ELOVL fatty acid elongase 3 multiple interactions ISO Dactinomycin inhibits the reaction [Norepinephrine results in increased expression of ELOVL3 mRNA]; Dactinomycin inhibits the reaction [rosiglitazone results in increased expression of ELOVL3 mRNA] CTD PMID:17726147 NCBI chr 1:265,883,353...265,887,181
Ensembl chr 1:265,883,355...265,887,226
JBrowse link
G Emp1 epithelial membrane protein 1 increases expression ISO Dactinomycin results in increased expression of EMP1 mRNA CTD PMID:21527772 NCBI chr 4:169,161,076...169,181,967
Ensembl chr 4:169,147,243...169,181,966
JBrowse link
G Emp3 epithelial membrane protein 3 increases expression ISO Dactinomycin results in increased expression of EMP3 mRNA CTD PMID:21527772 NCBI chr 1:101,900,731...101,903,948
Ensembl chr 1:101,900,733...101,903,910
JBrowse link
G Epas1 endothelial PAS domain protein 1 increases stability EXP Dactinomycin results in increased stability of EPAS1 protein CTD PMID:23545307 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265
JBrowse link
G F3 coagulation factor III, tissue factor decreases expression
multiple interactions
ISO Dactinomycin results in decreased expression of F3 mRNA
Dactinomycin inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA]
CTD PMID:30324315 NCBI chr 2:225,310,686...225,322,281
Ensembl chr 2:225,310,624...225,322,272
JBrowse link
G Fadd Fas associated via death domain decreases expression ISO Dactinomycin results in decreased expression of FADD mRNA CTD PMID:16001973 NCBI chr 1:217,746,176...217,748,581
Ensembl chr 1:217,742,929...217,748,628
JBrowse link
G Fads3 fatty acid desaturase 3 increases expression ISO Dactinomycin results in increased expression of FADS3 mRNA CTD PMID:21527772 NCBI chr 1:226,091,774...226,108,332
Ensembl chr 1:226,091,774...226,108,332
JBrowse link
G Fbl fibrillarin affects localization ISO Dactinomycin analog affects the localization of FBL protein CTD PMID:10942594 NCBI chr 1:85,103,519...85,112,619
Ensembl chr 1:85,103,519...85,112,619
JBrowse link
G Fcar Fc fragment of IgA receptor multiple interactions ISO Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of FCAR mRNA] CTD PMID:21911031 NCBI chr 1:73,230,392...73,263,462
Ensembl chr 1:73,230,390...73,264,302
JBrowse link
G Fgf2 fibroblast growth factor 2 multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA]
Dactinomycin inhibits the reaction [FGF2 protein results in increased expression of SNCA protein]
Dactinomycin results in decreased expression of FGF2 mRNA
CTD PMID:12562524, PMID:26800359 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fgfr1 Fibroblast growth factor receptor 1 multiple interactions EXP Dactinomycin inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA] CTD PMID:12805413 NCBI chr16:71,265,390...71,319,046
Ensembl chr16:71,266,248...71,319,449
JBrowse link
G Fhl1 four and a half LIM domains 1 multiple interactions EXP Dactinomycin promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA] CTD PMID:17161435 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Flnc filamin C increases expression ISO Dactinomycin results in increased expression of FLNC mRNA CTD PMID:21527772 NCBI chr 4:56,710,934...56,738,779
Ensembl chr 4:56,711,049...56,738,791
JBrowse link
G Fn1 fibronectin 1 multiple interactions ISO Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of FN1 mRNA] CTD PMID:18253093 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA]
Dactinomycin inhibits the reaction [Hemin results in increased expression of FOS mRNA]
Dactinomycin results in decreased expression of FOS mRNA
Dactinomycin inhibits the reaction [[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Fructose results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA]
CTD PMID:1696944, PMID:7564102, PMID:10381381, PMID:11123204, PMID:11353138, PMID:11568973, PMID:12632255 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of FOSL1 mRNA]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of FOSL1 mRNA]
Dactinomycin results in decreased expression of FOSL1 mRNA
CTD PMID:14565943 NCBI chr 1:220,826,560...220,835,066
Ensembl chr 1:220,826,560...220,835,066
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase multiple interactions EXP Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] CTD PMID:1978808 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha multiple interactions
increases expression
ISO Dactinomycin inhibits the reaction [arsenite results in increased expression of GADD45A mRNA]
Dactinomycin results in increased expression of GADD45A mRNA
CTD PMID:17616671, PMID:21527772 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Galm galactose mutarotase multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of GALM mRNA] CTD PMID:18052213 NCBI chr 6:2,808,988...2,860,742
Ensembl chr 6:2,808,841...2,860,744
JBrowse link
G Gapdh glyceraldehyde-3-phosphate dehydrogenase increases expression ISO Dactinomycin results in increased expression of GAPDH mRNA CTD PMID:16001973 NCBI chr 4:157,676,336...157,680,322
Ensembl chr 4:157,676,595...157,679,962
JBrowse link
G Gas6 growth arrest specific 6 multiple interactions
increases degradation
ISO Phosphates promotes the reaction [Dactinomycin results in increased degradation of GAS6 mRNA] CTD PMID:20048160 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [Vitamin K 3 results in increased expression of GCLC mRNA]
Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein]
CTD PMID:11972604, PMID:24437944 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gdf15 growth differentiation factor 15 multiple interactions ISO Dactinomycin inhibits the reaction [resveratrol results in increased expression of GDF15 mRNA] CTD PMID:17257620 NCBI chr16:20,555,395...20,557,978
Ensembl chr16:20,555,395...20,557,978
JBrowse link
G Gdnf glial cell derived neurotrophic factor multiple interactions
decreases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of GDNF mRNA]
Dactinomycin results in decreased expression of GDNF mRNA
CTD PMID:22982731 NCBI chr 2:56,884,181...56,912,964
Ensembl chr 2:56,887,987...56,910,238
JBrowse link
G Gfer growth factor, augmenter of liver regeneration increases secretion
multiple interactions
EXP Dactinomycin results in increased secretion of GFER protein
Dactinomycin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of GFER protein]; lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Dactinomycin results in increased secretion of GFER protein]
CTD PMID:23073658 NCBI chr10:14,059,347...14,061,703
Ensembl chr10:14,059,347...14,061,703
JBrowse link
G Gpr137b G protein-coupled receptor 137B increases expression ISO Dactinomycin results in increased expression of GPR137B mRNA CTD PMID:21527772 NCBI chr17:90,670,852...90,709,003
Ensembl chr17:90,670,872...90,746,804
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] CTD PMID:29479035 NCBI chr 7:117,759,083...117,761,932
Ensembl chr 7:117,759,083...117,761,931
JBrowse link
G Grm5 glutamate metabotropic receptor 5 multiple interactions EXP Dactinomycin inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 mRNA]; Dactinomycin inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 protein] CTD PMID:11665859 NCBI chr 1:151,207,846...151,785,038
Ensembl chr 1:151,439,409...151,783,392
JBrowse link
G Gsta1 glutathione S-transferase alpha 1 multiple interactions ISO Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of GSTA1 mRNA] CTD PMID:28483492 NCBI chr 9:27,366,404...27,381,004
Ensembl chr 9:27,368,272...27,452,902
JBrowse link
G Gsta2 glutathione S-transferase alpha 2 multiple interactions ISO Dactinomycin inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA] CTD PMID:16243960 NCBI chr 8:85,640,081...85,645,621 JBrowse link
G Gsta6 glutathione S-transferase alpha 6 multiple interactions ISO Dactinomycin inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA] CTD PMID:16243960 NCBI chr 9:27,475,273...27,533,939
Ensembl chr 9:27,475,273...27,511,176
JBrowse link
G Gstp1 glutathione S-transferase pi 1 decreases response to substance EXP GSTP1 protein results in decreased susceptibility to Dactinomycin CTD PMID:11455017 NCBI chr 1:219,291,679...219,294,147
Ensembl chr 1:219,291,679...219,294,147
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Dactinomycin results in increased expression of H2AX protein CTD PMID:31226288 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hbegf heparin-binding EGF-like growth factor multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA]
Dactinomycin results in decreased expression of HBEGF mRNA
CTD PMID:26800359 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hgf hepatocyte growth factor multiple interactions ISO Dactinomycin inhibits the reaction [Berberine results in increased expression of HGF protein] CTD PMID:29408570 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions ISO Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of HIF1A protein] CTD PMID:12479793, PMID:19958256 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [Ammonium Chloride results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Lipid Peroxides results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Nitroprusside results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Plant Extracts results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Potassium Dichromate results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Ritonavir results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 protein]; Dactinomycin results in decreased susceptibility to [surfactin peptide results in increased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]]
Dactinomycin results in decreased expression of HMOX1 protein
Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA]
Dactinomycin inhibits the reaction [fisetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Triterpenes analog results in increased expression of HMOX1 protein]
CTD PMID:8764571, PMID:9747510, PMID:9808084, PMID:11880364, PMID:12763371, PMID:15118350, PMID:15582353, PMID:15588712, PMID:15876423, PMID:15965080, PMID:16647178, PMID:17002867, PMID:18332044, PMID:18357586, PMID:19781563, PMID:20060010, PMID:20833156, PMID:21840424, PMID:24437944, PMID:25239868, PMID:26283888, PMID:26385185, PMID:26968795, PMID:27867098, PMID:30076913 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 multiple interactions
affects localization
ISO Dactinomycin affects the reaction [HNRNPA1 protein binds to CYP2A5 mRNA]
Dactinomycin affects the localization of HNRNPA1 protein
CTD PMID:12754101 NCBI chr 7:144,865,302...144,871,592
Ensembl chr 7:144,865,608...144,871,585
JBrowse link
G Homer3 homer scaffold protein 3 increases expression ISO Dactinomycin results in increased expression of HOMER3 mRNA CTD PMID:21527772 NCBI chr16:20,880,447...20,890,968
Ensembl chr16:20,881,518...20,890,949
JBrowse link
G Hras HRas proto-oncogene, GTPase multiple interactions ISO Dactinomycin promotes the reaction [[Zinostatin co-treated with Glutathione] results in increased cleavage of HRAS gene] CTD PMID:9345283 NCBI chr 1:214,178,404...214,181,841
Ensembl chr 1:214,178,407...214,181,686
JBrowse link
G Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 multiple interactions ISO Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA] CTD PMID:31927052 NCBI chr19:37,476,083...37,481,326
Ensembl chr19:37,476,095...37,481,307
JBrowse link
G Hsf1 heat shock transcription factor 1 multiple interactions ISO Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of HSF1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of HSF1 protein] CTD PMID:30309986 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [lead acetate results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] CTD PMID:17915553 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Htr3a 5-hydroxytryptamine receptor 3A multiple interactions ISO Dactinomycin promotes the reaction [Dronabinol results in decreased activity of HTR3A protein] CTD PMID:20800662 NCBI chr 8:53,211,436...53,223,878
Ensembl chr 8:53,211,438...53,223,804
JBrowse link
G Id1 inhibitor of DNA binding 1, HLH protein multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of ID1 mRNA] CTD PMID:16494909 NCBI chr 3:148,214,623...148,216,715
Ensembl chr 3:148,215,540...148,216,718
JBrowse link
G Ier3 immediate early response 3 multiple interactions ISO Dactinomycin inhibits the reaction [afimoxifene results in increased expression of IER3 mRNA] CTD PMID:16849584 NCBI chr20:3,438,798...3,440,002
Ensembl chr20:3,438,798...3,440,769
JBrowse link
G Ier5 immediate early response 5 increases expression ISO Dactinomycin results in increased expression of IER5 mRNA CTD PMID:21527772 NCBI chr13:72,742,210...72,744,302
Ensembl chr13:72,742,210...72,744,303
JBrowse link
G Ifnb1 interferon beta 1 multiple interactions ISO Dactinomycin inhibits the reaction [IFNB1 protein results in increased expression of TYMP mRNA] CTD PMID:15937643 NCBI chr 5:106,865,192...106,865,746
Ensembl chr 5:106,865,192...106,865,746
JBrowse link
G Ifng interferon gamma multiple interactions ISO [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA]; Dactinomycin inhibits the reaction [IFNG protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [Tretinoin promotes the reaction [IFNG protein results in increased expression of IRF1 protein]] CTD PMID:15937643, PMID:16085646, PMID:26278786, PMID:29594315 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 decreases response to substance ISO IGF1 protein results in decreased susceptibility to Dactinomycin CTD PMID:9525472 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 multiple interactions ISO Dactinomycin inhibits the reaction [Zymosan results in increased expression of IL10 mRNA] CTD PMID:17458858 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il11 interleukin 11 multiple interactions ISO Dactinomycin inhibits the reaction [Formaldehyde results in increased expression of IL11 mRNA] CTD PMID:22138297 NCBI chr 1:72,636,959...72,643,255
Ensembl chr 1:72,635,267...72,643,255
JBrowse link
G Il17a interleukin 17A multiple interactions ISO Dactinomycin inhibits the reaction [Glucose results in increased secretion of IL17A protein] CTD PMID:18310510 NCBI chr 9:26,841,299...26,844,786
Ensembl chr 9:26,841,299...26,844,786
JBrowse link
G Il1a interleukin 1 alpha multiple interactions EXP Dactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA] CTD PMID:7564102 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of TGFB1 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased secretion of TGFB1 protein]; Dactinomycin inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Dactinomycin inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Dactinomycin inhibits the reaction [IL1B results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [IL1B results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [IL1B results in increased secretion of CSF2 protein]
Dactinomycin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA alternative form]; Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA]
CTD PMID:9606035, PMID:11286988, PMID:12512699, PMID:16338976, PMID:16365456, PMID:16492401, PMID:17641275 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il2 interleukin 2 multiple interactions ISO [Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA CTD PMID:29594315 NCBI chr 2:123,847,150...123,851,854
Ensembl chr 2:123,847,150...123,851,854
JBrowse link
G Il27ra interleukin 27 receptor subunit alpha increases expression ISO Dactinomycin results in increased expression of IL27RA mRNA CTD PMID:21527772 NCBI chr19:25,151,835...25,163,995
Ensembl chr19:25,149,897...25,164,086
JBrowse link
G Il6 interleukin 6 decreases secretion ISO Dactinomycin results in decreased secretion of IL6 protein CTD PMID:11216681 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Ins2 insulin 2 multiple interactions ISO Dactinomycin inhibits the reaction [[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased expression of SLC27A1 mRNA] CTD PMID:10777552 NCBI chr 1:215,856,967...215,858,034
Ensembl chr 1:215,856,971...215,858,034
JBrowse link
G Irf1 interferon regulatory factor 1 multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin promotes the reaction [IFNG protein results in increased expression of IRF1 protein]]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of IRF1 mRNA] CTD PMID:16085646, PMID:16636311 NCBI chr10:39,109,530...39,116,532
Ensembl chr10:39,109,522...39,116,531
JBrowse link
G Itga2b integrin subunit alpha 2b increases expression ISO Dactinomycin results in increased expression of ITGA2B mRNA CTD PMID:21527772 NCBI chr10:90,397,960...90,416,550
Ensembl chr10:90,398,132...90,415,070
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 multiple interactions ISO Dactinomycin inhibits the reaction [Ethanol results in increased expression of ITPR1 mRNA]; Dactinomycin inhibits the reaction [linsidomine results in increased expression of ITPR1 mRNA] CTD PMID:17241155 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Jak2 Janus kinase 2 multiple interactions EXP Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] CTD PMID:15932931 NCBI chr 1:247,398,667...247,457,521
Ensembl chr 1:247,398,598...247,458,509
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]
Dactinomycin results in decreased expression of JUN mRNA
Dactinomycin inhibits the reaction [Cadmium results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Fructose results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of JUN mRNA]
CTD PMID:1696944, PMID:11123204, PMID:11353138, PMID:11568973 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Kif1a kinesin family member 1A increases expression ISO Dactinomycin results in increased expression of KIF1A mRNA CTD PMID:21527772 NCBI chr 9:100,171,851...100,253,626
Ensembl chr 9:100,171,772...100,253,609
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO Dactinomycin inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased expression of TNFRSF10B mRNA] CTD PMID:27222248 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt80 keratin 80 increases expression ISO Dactinomycin results in increased expression of KRT80 mRNA CTD PMID:21527772 NCBI chr 7:142,995,715...143,015,932
Ensembl chr 7:142,994,119...143,016,040
JBrowse link
G Lamc2 laminin subunit gamma 2 increases expression ISO Dactinomycin results in increased expression of LAMC2 mRNA CTD PMID:21527772 NCBI chr13:70,566,643...70,632,126
Ensembl chr13:70,566,643...70,626,252
JBrowse link
G Lep leptin multiple interactions EXP Dactinomycin inhibits the reaction [LEP protein results in increased expression of COL1A2 mRNA] CTD PMID:12704794 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals3 galectin 3 multiple interactions ISO Dactinomycin inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein] CTD PMID:21821001 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lgals7 galectin 7 increases expression ISO Dactinomycin results in increased expression of LGALS7 mRNA CTD PMID:21527772 NCBI chr 1:87,044,823...87,047,223
Ensembl chr 1:87,045,335...87,047,223
JBrowse link
G Lmnb1 lamin B1 decreases expression ISO Dactinomycin results in decreased expression of LMNB1 mRNA CTD PMID:16001973 NCBI chr18:51,785,111...51,822,264
Ensembl chr18:51,785,111...51,822,264
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta multiple interactions ISO Dactinomycin inhibits the reaction [Ethanol results in increased expression of MAP1LC3B protein] CTD PMID:24095927 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Map2k4 mitogen activated protein kinase kinase 4 decreases expression ISO Dactinomycin results in decreased expression of MAP2K4 mRNA CTD PMID:16001973 NCBI chr10:52,196,121...52,301,887
Ensembl chr10:52,196,124...52,290,657
JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 decreases expression ISO Dactinomycin results in decreased expression of MAP3K7 mRNA CTD PMID:16001973 NCBI chr 5:47,183,142...47,244,424
Ensembl chr 5:47,186,558...47,244,416
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
increases expression
ISO
EXP
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]
PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]
Dactinomycin results in increased expression of MAPK1 protein
CTD PMID:14640974, PMID:15959627 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
increases expression
ISO
EXP
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Dactinomycin results in increased expression of MAPK3 protein
PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]
CTD PMID:14640974, PMID:15959627 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member decreases expression
multiple interactions
ISO Dactinomycin results in decreased expression of MCL1 mRNA
Dactinomycin inhibits the reaction [IL1B results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of MCL1 protein]; Quercetin promotes the reaction [Dactinomycin results in decreased expression of MCL1 mRNA]
CTD PMID:16492401, PMID:21750559 NCBI chr 2:197,786,212...197,788,992 JBrowse link
G Mir21 microRNA 21 multiple interactions ISO Dactinomycin inhibits the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [Dihydrotestosterone results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA] CTD PMID:19264808, PMID:23052036, PMID:25969534 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir22 microRNA 22 multiple interactions ISO [Dactinomycin co-treated with Dehydroepiandrosterone] results in increased expression of MIR22 mRNA; Dactinomycin promotes the reaction [Dehydroepiandrosterone results in increased expression of MIR22 mRNA] CTD PMID:25969534 NCBI chr10:62,299,592...62,299,686
Ensembl chr10:62,299,592...62,299,686
JBrowse link
G Mllt11 MLLT11, transcription factor 7 cofactor increases expression ISO Dactinomycin results in increased expression of MLLT11 mRNA CTD PMID:21527772 NCBI chr 2:196,392,936...196,402,106
Ensembl chr 2:196,392,938...196,402,106
JBrowse link
G Mmp1 matrix metallopeptidase 1 multiple interactions ISO Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein] CTD PMID:19136476 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp9 matrix metallopeptidase 9 multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [arsenic trioxide results in increased expression of MMP9 mRNA]
Dactinomycin results in decreased expression of MMP9 mRNA
CTD PMID:24956101 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mn1 MN1 proto-oncogene, transcriptional regulator multiple interactions ISO Dactinomycin inhibits the reaction [Calcitriol results in increased expression of MN1 mRNA] CTD PMID:15890672 NCBI chr12:51,214,192...51,250,230
Ensembl chr12:51,214,192...51,250,230
JBrowse link
G Mrpl41 mitochondrial ribosomal protein L41 multiple interactions ISO Dactinomycin promotes the reaction [MRPL41 protein results in increased stability of and affects the localization of TP53 protein] CTD PMID:16024796 NCBI chr 3:2,181,044...2,181,962
Ensembl chr 3:2,181,045...2,181,962
JBrowse link
G Mt1 metallothionein 1 multiple interactions ISO Dactinomycin inhibits the reaction [Buthionine Sulfoximine promotes the reaction [Paraquat results in increased expression of MT1 mRNA]]; Dactinomycin inhibits the reaction [Paraquat results in increased expression of MT1 mRNA] CTD PMID:8966720 NCBI chr19:11,301,991...11,303,007
Ensembl chr17:78,793,336...78,793,724
JBrowse link
G Mt2A metallothionein 2A multiple interactions ISO Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA] CTD PMID:17234632 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Mttp microsomal triglyceride transfer protein multiple interactions EXP Dactinomycin inhibits the reaction [pirinixic acid results in increased expression of MTTP mRNA] CTD PMID:15537571 NCBI chr 2:243,366,181...243,407,608
Ensembl chr 2:243,366,181...243,407,608
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression
multiple interactions
ISO
EXP
Dactinomycin results in decreased expression of MYC mRNA
Dactinomycin inhibits the reaction [Cadmium results in increased expression of MYC mRNA]
Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of MYC mRNA]
CTD PMID:1696944, PMID:11353138, PMID:16001973, PMID:21527772 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Mylk myosin light chain kinase multiple interactions ISO Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK protein] CTD PMID:15701621 NCBI chr11:69,013,060...69,260,039
Ensembl chr11:69,013,050...69,223,158
JBrowse link
G Nav2 neuron navigator 2 multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of NAV2 mRNA] CTD PMID:16688769 NCBI chr 1:104,575,765...104,941,554
Ensembl chr 1:104,576,589...104,941,552
JBrowse link
G Ncf1 neutrophil cytosolic factor 1 multiple interactions ISO Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of NCF1 mRNA] CTD PMID:19559082 NCBI chr12:25,497,104...25,506,300
Ensembl chr12:25,497,104...25,506,300
JBrowse link
G Ndrg1 N-myc downstream regulated 1 multiple interactions ISO [nickel chloride co-treated with Dactinomycin] results in increased stability of NDRG1 mRNA; [Oxygen deficiency co-treated with Dactinomycin] results in increased stability of NDRG1 mRNA CTD PMID:10646848 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 multiple interactions ISO Dactinomycin inhibits the reaction [Tretinoin results in increased expression of NEDD9 mRNA] CTD PMID:16688769 NCBI chr17:22,984,792...23,179,701
Ensembl chr17:22,984,844...23,179,701
JBrowse link
G Neto2 neuropilin and tolloid like 2 increases expression ISO Dactinomycin results in increased expression of NETO2 mRNA CTD PMID:21527772 NCBI chr19:22,450,579...22,486,530
Ensembl chr19:22,450,030...22,486,531
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 multiple interactions ISO Dactinomycin inhibits the reaction [sulforafan results in increased expression of NFE2L2 protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFE2L2 mRNA] CTD PMID:22019695, PMID:24632381 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 decreases expression
multiple interactions
ISO Dactinomycin results in decreased expression of NFKB1 mRNA
[RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]
CTD PMID:11880364, PMID:16001973 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]] CTD PMID:11880364 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Ngf nerve growth factor multiple interactions
decreases expression
EXP Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of NGF mRNA]
Dactinomycin results in decreased expression of NGF mRNA
CTD PMID:22982731 NCBI chr 2:204,886,158...204,939,523
Ensembl chr 2:204,886,202...204,940,453
JBrowse link
G Nlrp3 NLR family, pyrin domain containing 3 multiple interactions ISO Dactinomycin inhibits the reaction [Asbestos, Crocidolite results in increased expression of NLRP3 mRNA] CTD PMID:23937860 NCBI chr10:45,884,324...45,918,290
Ensembl chr10:45,893,018...45,918,254
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Dactinomycin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA] CTD PMID:11286988 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Nppc natriuretic peptide C multiple interactions ISO Dactinomycin inhibits the reaction [Estradiol results in increased expression of NPPC mRNA] CTD PMID:9435603 NCBI chr 9:93,731,436...93,735,636
Ensembl chr 9:93,731,436...93,735,636
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [Biological Products results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Itraconazole results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Dactinomycin promotes the reaction [Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]]
Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein]
CTD PMID:16243960, PMID:17923278, PMID:18474416, PMID:22570534, PMID:24437944 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr0b1 nuclear receptor subfamily 0, group B, member 1 multiple interactions ISO Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA] CTD PMID:18787026 NCBI chr  X:54,734,385...54,738,513
Ensembl chr  X:54,734,385...54,738,513
JBrowse link
G Nr0b2 nuclear receptor subfamily 0, group B, member 2 multiple interactions ISO Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA] CTD PMID:19593819 NCBI chr 5:151,776,004...151,779,319
Ensembl chr 5:151,776,004...151,779,319
JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO Dactinomycin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:30,003,429...30,162,095
Ensembl chr 7:30,003,429...30,162,056
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP
ISO
Dactinomycin inhibits the reaction [Clofibrate results in increased expression of NR1I2 protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]; Dactinomycin inhibits the reaction [perfluorodecanoic acid results in increased expression of NR1I2 protein]
Dactinomycin inhibits the reaction [ochratoxin A results in decreased expression of NR1I2 mRNA]
CTD PMID:15826607, PMID:20599767, PMID:26341324 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 multiple interactions ISO Dactinomycin inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; Dactinomycin inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein] CTD PMID:21569845 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nthl1 nth-like DNA glycosylase 1 decreases expression ISO Dactinomycin results in decreased expression of NTHL1 mRNA CTD PMID:21527772 NCBI chr10:13,996,660...14,002,827
Ensembl chr10:13,996,645...14,002,910
JBrowse link
G Opa1 OPA1, mitochondrial dynamin like GTPase multiple interactions EXP Dactinomycin inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form] CTD PMID:20678484 NCBI chr11:74,717,600...74,793,902
Ensembl chr11:74,720,254...74,793,803
JBrowse link
G Pappa1 pappalysin 1 multiple interactions ISO Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PAPPA mRNA] CTD PMID:16338976 NCBI chr 5:80,919,932...81,153,904
Ensembl chr 5:80,920,568...81,150,940
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions ISO [TNF co-treated with Dactinomycin] results in increased cleavage of PARP1 protein; Dactinomycin promotes the reaction [TNF results in increased cleavage of PARP1 protein]; PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]
PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]
CTD PMID:14640974, PMID:16492401 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcna proliferating cell nuclear antigen decreases expression
multiple interactions
EXP
ISO
Dactinomycin results in decreased expression of PCNA protein
Dactinomycin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein]
CTD PMID:15959627, PMID:21533478 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAT mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]; Dactinomycin inhibits the reaction [Resveratrol results in increased expression of PLAT mRNA] CTD PMID:11236827 NCBI chr16:74,098,263...74,122,897
Ensembl chr16:74,098,260...74,122,889
JBrowse link
G Plau plasminogen activator, urokinase multiple interactions
increases expression
ISO Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAU mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAU mRNA]; Dactinomycin inhibits the reaction [resveratrol results in increased expression of PLAU mRNA]
Dactinomycin results in increased expression of PLAU mRNA
CTD PMID:11236827, PMID:21527772 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pld1 phospholipase D1 multiple interactions ISO PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]; PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 NCBI chr 2:113,651,967...113,849,403
Ensembl chr 2:113,652,348...113,849,403
JBrowse link
G Pld2 phospholipase D2 multiple interactions ISO PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]; PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] CTD PMID:14640974 NCBI chr10:57,161,921...57,181,148
Ensembl chr10:57,163,174...57,179,730
JBrowse link
G Polh DNA polymerase eta multiple interactions ISO Dactinomycin inhibits the reaction [fotemustine results in increased expression of POLH mRNA] CTD PMID:25125662 NCBI chr 9:17,163,354...17,198,006
Ensembl chr 9:17,163,354...17,197,132
JBrowse link
G Polr2a RNA polymerase II subunit A decreases phosphorylation
increases phosphorylation
multiple interactions
ISO Dactinomycin results in decreased phosphorylation of POLR2A protein
Dactinomycin results in increased phosphorylation of POLR2A protein
[Dactinomycin co-treated with sodium arsenite] results in increased phosphorylation of POLR2A protein
CTD PMID:8126066 NCBI chr10:56,339,277...56,364,888
Ensembl chr10:56,339,284...56,365,084
JBrowse link
G Pomt1 protein-O-mannosyltransferase 1 increases expression ISO Dactinomycin results in increased expression of POMT1 mRNA CTD PMID:21527772 NCBI chr 3:11,253,424...11,271,873
Ensembl chr 3:11,254,026...11,271,872
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO Dactinomycin inhibits the reaction [sodium arsenate results in increased expression of PRDX1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenate results in increased expression of PRDX1 protein] CTD PMID:11796722 NCBI chr 5:135,536,413...135,551,986
Ensembl chr 5:135,536,413...135,551,990
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions EXP Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased expression of PRDX6 mRNA]; Dactinomycin inhibits the reaction [Paraquat results in increased expression of PRDX6 mRNA] CTD PMID:12851211 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prkcd protein kinase C, delta multiple interactions ISO PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]
PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]
CTD PMID:14640974 NCBI chr16:6,655,131...6,675,746
Ensembl chr16:6,655,120...6,675,746
JBrowse link
G Prl prolactin multiple interactions ISO Dactinomycin inhibits the reaction [PRL protein results in increased expression of SLC30A2 mRNA] CTD PMID:19494234 NCBI chr17:39,814,236...39,824,299
Ensembl chr17:39,814,244...39,824,299
JBrowse link
G Procr protein C receptor increases expression ISO Dactinomycin results in increased expression of PROCR mRNA CTD PMID:21527772 NCBI chr 3:151,285,321...151,289,581
Ensembl chr 3:151,285,249...151,289,595
JBrowse link
G Prom1 prominin 1 decreases expression
multiple interactions
ISO Dactinomycin results in decreased expression of PROM1 mRNA
Dactinomycin results in decreased expression of and affects the localization of PROM1 protein
CTD PMID:31226288 NCBI chr14:71,532,321...71,637,400
Ensembl chr14:71,533,063...71,637,417
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions
decreases expression
ISO
EXP
Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Sodium Fluoride results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [Zinc results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Zinc results in increased expression of PTGS2 protein]
Dactinomycin inhibits the reaction [nickel chloride results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [nickel sulfide results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]
Dactinomycin results in decreased expression of PTGS2 mRNA
Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA]
CTD PMID:9576062, PMID:11286988, PMID:16894348, PMID:17065197, PMID:18513776, PMID:18650268, PMID:19376214, PMID:24967690 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptk2 protein tyrosine kinase 2 decreases expression EXP Dactinomycin results in decreased expression of PTK2 protein CTD PMID:15959627 NCBI chr 7:114,436,419...114,611,317
Ensembl chr 7:114,437,361...114,590,119
JBrowse link
G Rad51 RAD51 recombinase multiple interactions
decreases expression
ISO tetrachlorobenzoquinone promotes the reaction [Dactinomycin results in decreased expression of RAD51 mRNA] CTD PMID:27989139 NCBI chr 3:110,918,240...110,942,920
Ensembl chr 3:110,918,243...110,942,917
JBrowse link
G Raf1 Raf-1 proto-oncogene, serine/threonine kinase decreases expression EXP Dactinomycin results in decreased expression of RAF1 protein CTD PMID:15959627 NCBI chr 4:147,532,040...147,592,769
Ensembl chr 4:147,532,042...147,592,699
JBrowse link
G Rel REL proto-oncogene, NF-kB subunit multiple interactions ISO [RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr14:108,490,794...108,517,582
Ensembl chr14:108,491,069...108,509,892
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO [RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; RELA protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Ren renin multiple interactions ISO Dactinomycin inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Dactinomycin inhibits the reaction [Terbutaline results in increased secretion of REN protein] CTD PMID:9203624 NCBI chr13:50,502,724...50,513,953
Ensembl chr13:50,502,724...50,514,151
JBrowse link
G Retsat retinol saturase increases expression ISO Dactinomycin results in increased expression of RETSAT mRNA CTD PMID:21527772 NCBI chr 4:100,465,365...100,474,128
Ensembl chr 4:100,465,170...100,474,301
JBrowse link
G Rhob ras homolog family member B multiple interactions ISO Dactinomycin inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB mRNA]; Dactinomycin inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB protein] CTD PMID:23732113 NCBI chr 6:33,689,127...33,691,301
Ensembl chr 6:33,689,127...33,691,301
JBrowse link
G Ripply3 ripply transcriptional repressor 3 increases expression ISO Dactinomycin results in increased expression of RIPPLY3 mRNA CTD PMID:21527772 NCBI chr11:34,557,679...34,565,776
Ensembl chr11:34,557,679...34,565,776
JBrowse link
G Rnf213 ring finger protein 213 multiple interactions ISO Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA] CTD PMID:26278786 NCBI chr10:108,527,351...108,626,372
Ensembl chr10:108,527,740...108,624,688
JBrowse link
G Ros1 ROS proto-oncogene 1 , receptor tyrosine kinase increases expression ISO Dactinomycin results in increased expression of ROS1 mRNA CTD PMID:16001973 NCBI chr20:33,100,190...33,323,544
Ensembl chr20:33,100,191...33,323,367
JBrowse link
G Rpl34 ribosomal protein L34 increases expression ISO Dactinomycin results in increased expression of RPL34 mRNA CTD PMID:21527772 NCBI chr 2:235,850,281...235,854,021
Ensembl chr 2:235,850,334...235,852,708
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 multiple interactions ISO PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]
PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]
CTD PMID:14640974 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364
JBrowse link
G Rras RAS related increases expression ISO Dactinomycin results in increased expression of RRAS mRNA CTD PMID:21527772 NCBI chr 1:101,012,822...101,016,720
Ensembl chr 1:101,012,822...101,016,720
JBrowse link
G Sat1 spermidine/spermine N1-acetyl transferase 1 multiple interactions ISO Dactinomycin inhibits the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA] CTD PMID:16637064 NCBI chr  X:43,626,480...43,629,767
Ensembl chr  X:43,625,169...43,629,765
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions ISO Dactinomycin inhibits the reaction [ciprofibrate results in increased expression of SCD1 mRNA] CTD PMID:11172741 NCBI chr 1:264,159,966...264,173,061
Ensembl chr 1:264,160,129...264,172,729
JBrowse link
G Scnn1b sodium channel epithelial 1 subunit beta multiple interactions ISO Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of SCNN1B mRNA] CTD PMID:10942727 NCBI chr 1:191,829,547...191,883,991
Ensembl chr 1:191,829,555...191,884,298
JBrowse link
G Scnn1g sodium channel epithelial 1 subunit gamma multiple interactions ISO Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of SCNN1G mRNA] CTD PMID:10942727 NCBI chr 1:191,704,397...191,738,271
Ensembl chr 1:191,704,311...191,738,268
JBrowse link
G Sdc3 syndecan 3 multiple interactions EXP Dactinomycin inhibits the reaction [Estradiol results in increased expression of SDC3 mRNA] CTD PMID:11024013 NCBI chr 5:148,923,098...148,956,404
Ensembl chr 5:148,923,098...148,956,404
JBrowse link
G Sesn2 sestrin 2 multiple interactions ISO Dactinomycin inhibits the reaction [erastin results in increased expression of SESN2 mRNA] CTD PMID:31323261 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sfn stratifin increases expression ISO Dactinomycin results in increased expression of SFN mRNA CTD PMID:21527772 NCBI chr 5:151,823,422...151,824,937
Ensembl chr 5:151,823,887...151,824,633
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 multiple interactions ISO Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 protein] CTD PMID:25128767 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Shh sonic hedgehog signaling molecule multiple interactions ISO Dactinomycin inhibits the reaction [SHH protein alternative form results in increased expression of ABCG2 protein] CTD PMID:21625222 NCBI chr 4:718,538...727,691
Ensembl chr 4:718,538...727,691
JBrowse link
G Sirt1 sirtuin 1 multiple interactions ISO Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA] CTD PMID:30055241 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc25a14 solute carrier family 25 member 14 multiple interactions ISO Dactinomycin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SLC25A14 mRNA]; Dactinomycin inhibits the reaction [Dopamine results in increased expression of SLC25A14 mRNA] CTD PMID:20600837 NCBI chr  X:135,470,855...135,509,223
Ensembl chr  X:135,470,915...135,509,221
JBrowse link
G Slc27a1 solute carrier family 27 member 1 multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased expression of SLC27A1 mRNA]
Dactinomycin inhibits the reaction [alitretinoin results in increased expression of SLC27A1 mRNA]
CTD PMID:10777552 NCBI chr16:19,997,823...20,016,193
Ensembl chr16:19,999,112...20,016,190
JBrowse link
G Slc2a2 solute carrier family 2 member 2 multiple interactions EXP Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A2 mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of SLC2A2 mRNA] CTD PMID:12787936 NCBI chr 2:114,413,427...114,445,418
Ensembl chr 2:114,413,410...114,445,395
JBrowse link
G Slc2a5 solute carrier family 2 member 5 multiple interactions EXP Dactinomycin inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]]; Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] CTD PMID:11123204 NCBI chr 5:167,142,182...167,174,203
Ensembl chr 5:167,141,875...167,174,310
JBrowse link
G Slc30a2 solute carrier family 30 member 2 multiple interactions ISO Dactinomycin inhibits the reaction [PRL protein results in increased expression of SLC30A2 mRNA] CTD PMID:19494234 NCBI chr 5:152,559,577...152,571,800
Ensembl chr 5:152,559,577...152,571,799
JBrowse link
G Slc30a5 solute carrier family 30 member 5 multiple interactions ISO Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA] CTD PMID:17234632 NCBI chr 2:30,815,683...30,845,796
Ensembl chr 2:30,815,703...30,846,149
JBrowse link
G Slc39a10 solute carrier family 39 member 10 multiple interactions ISO Dactinomycin inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA] CTD PMID:21738690 NCBI chr 9:59,947,562...60,070,549
Ensembl chr 9:60,021,534...60,070,552
JBrowse link
G Slc39a4 solute carrier family 39 member 4 multiple interactions ISO Dactinomycin inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Dactinomycin inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] CTD PMID:18020946 NCBI chr 7:117,675,718...117,682,586
Ensembl chr 7:117,675,720...117,680,004
JBrowse link
G Slc3a2 solute carrier family 3 member 2 multiple interactions ISO Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of SLC3A2 mRNA] CTD PMID:26621329 NCBI chr 1:224,906,566...224,921,029
Ensembl chr 1:224,906,554...224,921,092
JBrowse link
G Slc40a1 solute carrier family 40 member 1 multiple interactions ISO Dactinomycin inhibits the reaction [Cadmium results in increased expression of SLC40A1 mRNA] CTD PMID:20090884 NCBI chr 9:52,819,451...52,830,461
Ensembl chr 9:52,894,365...52,912,293
JBrowse link
G Slc7a11 solute carrier family 7 member 11 decreases expression ISO Dactinomycin results in decreased expression of SLC7A11 protein CTD PMID:31226288 NCBI chr 2:139,453,774...139,528,479
Ensembl chr 2:139,453,774...139,528,162
JBrowse link
G Slc7a5 solute carrier family 7 member 5 multiple interactions ISO Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of SLC7A5 mRNA] CTD PMID:26621329 NCBI chr19:54,693,959...54,722,563
Ensembl chr19:54,693,959...54,722,563
JBrowse link
G Snca synuclein alpha multiple interactions EXP Dactinomycin inhibits the reaction [FGF2 protein results in increased expression of SNCA protein] CTD PMID:12562524 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
G Socs3 suppressor of cytokine signaling 3 multiple interactions ISO Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA] CTD PMID:23237828 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [SOD2 protein results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; SOD2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]
Dactinomycin inhibits the reaction [polysaccharide-K results in increased expression of SOD2]
Dactinomycin inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA]
CTD PMID:9852137, PMID:11154046, PMID:11880364, PMID:12031898, PMID:14996425, PMID:15683720 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sos1 SOS Ras/Rac guanine nucleotide exchange factor 1 decreases expression ISO Dactinomycin results in decreased expression of SOS1 mRNA CTD PMID:16001973 NCBI chr 6:3,105,443...3,182,977
Ensembl chr 6:3,104,861...3,182,996
JBrowse link
G Sox17 SRY-box transcription factor 17 decreases localization ISO Dactinomycin results in decreased localization of SOX17 protein CTD PMID:24154490 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link
G Spata18 spermatogenesis associated 18 increases expression ISO Dactinomycin results in increased expression of SPATA18 mRNA CTD PMID:21527772 NCBI chr14:37,081,529...37,108,245
Ensembl chr14:37,081,427...37,108,341
JBrowse link
G Sqstm1 sequestosome 1 multiple interactions ISO Dactinomycin inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein]
Dactinomycin inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA]
CTD PMID:24095927, PMID:25301941 NCBI chr10:35,704,728...35,716,316
Ensembl chr10:35,704,730...35,716,294
JBrowse link
G Stat1 signal transducer and activator of transcription 1 increases expression ISO Dactinomycin results in increased expression of STAT1 mRNA CTD PMID:16001973 NCBI chr 9:54,287,540...54,327,958
Ensembl chr 9:54,287,541...54,484,533
JBrowse link
G Stmn3 stathmin 3 increases expression ISO Dactinomycin results in increased expression of STMN3 mRNA CTD PMID:21527772 NCBI chr 3:176,808,016...176,816,108
Ensembl chr 3:176,808,017...176,816,162
JBrowse link
G Stom stomatin increases expression ISO Dactinomycin results in increased expression of STOM mRNA CTD PMID:21527772 NCBI chr 3:14,515,576...14,538,199
Ensembl chr 3:14,514,868...14,538,241
JBrowse link
G Sult1a1 sulfotransferase family 1A member 1 multiple interactions ISO Dactinomycin inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] CTD PMID:16308312 NCBI chr 1:198,100,586...198,104,106
Ensembl chr 1:198,100,586...198,104,109
JBrowse link
G Tap1 transporter 1, ATP binding cassette subfamily B member increases expression ISO Dactinomycin results in increased expression of TAP1 mRNA CTD PMID:21527772 NCBI chr20:3,979,302...3,989,669
Ensembl chr20:3,979,035...3,989,669
JBrowse link
G Tat tyrosine aminotransferase multiple interactions EXP
ISO
Dactinomycin inhibits the reaction [Dexamethasone results in increased activity of TAT protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of TAT mRNA]; Dactinomycin inhibits the reaction [Ursodeoxycholic Acid promotes the reaction [Dexamethasone results in increased activity of TAT protein]] CTD PMID:9398635, PMID:20599767, PMID:28483492 NCBI chr19:41,675,639...41,686,195
Ensembl chr19:41,675,355...41,686,229
JBrowse link
G Tcf4 transcription factor 4 multiple interactions EXP Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of TCF4 mRNA] CTD PMID:20459685 NCBI chr18:65,285,320...65,507,983
Ensembl chr18:65,155,685...65,507,977
JBrowse link
G Tdo2 tryptophan 2,3-dioxygenase affects activity EXP Dactinomycin affects the activity of TDO2 protein CTD PMID:7306070 NCBI chr 2:180,897,059...180,914,919
Ensembl chr 2:180,897,011...180,914,940
JBrowse link
G Testin testin gene multiple interactions
decreases secretion
EXP Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of TESTIN mRNA]; Dactinomycin inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Dactinomycin inhibits the reaction [lonidamine results in increased secretion of TESTIN protein]
Dactinomycin results in decreased secretion of TESTIN protein
CTD PMID:11090432 NCBI chr17:4,194,796...4,225,376
Ensembl chr17:4,212,890...4,225,376
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions ISO Dactinomycin inhibits the reaction [IL1B protein results in increased expression of TGFB1 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased secretion of TGFB1 protein]; Dactinomycin inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA] CTD PMID:9145908, PMID:16365456 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]; Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of FN1 mRNA] CTD PMID:18253093 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Thra thyroid hormone receptor alpha multiple interactions ISO Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA alternative form]; Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA] CTD PMID:17641275 NCBI chr10:86,657,285...86,684,935
Ensembl chr10:86,657,285...86,684,933
JBrowse link
G Tiparp TCDD-inducible poly(ADP-ribose) polymerase multiple interactions ISO Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] CTD PMID:12147270 NCBI chr 2:157,316,293...157,342,979
Ensembl chr 2:157,316,266...157,341,469
JBrowse link
G Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 multiple interactions ISO Dactinomycin inhibits the reaction [Dihydrotestosterone results in increased expression of TMEFF2 mRNA] CTD PMID:23405127 NCBI chr 9:55,379,130...55,673,704
Ensembl chr 9:55,384,100...55,673,829
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases response to substance
ISO
EXP
[Dactinomycin co-treated with TNF protein] results in increased expression of BNIP3 mRNA; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Dactinomycin promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased expression of TNF mRNA]]
[Dactinomycin co-treated with TNF protein] results in increased activity of CASP3 protein; Dactinomycin inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA]
[RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [TNF co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF co-treated with Dactinomycin] results in increased activity of CASP7 protein; [TNF co-treated with Dactinomycin] results in increased cleavage of PARP1 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP7 protein; BCL2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; BCL2A1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; BIRC3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of HIF1A protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Dactinomycin inhibits the reaction [TNF results in increased abundance of Nitric Oxide]; Dactinomycin inhibits the reaction [TNF results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP3 protein]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP7 protein]; Dactinomycin promotes the reaction [TNF results in increased cleavage of PARP1 protein]; HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]]; RELA protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; SOD2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; TNFAIP3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]
CTD PMID:9576062, PMID:10100995, PMID:11592958, PMID:11880364, PMID:12479793, PMID:12812920, PMID:15531761, PMID:15701621, PMID:16338976, PMID:16492401, PMID:18845389, PMID:21496118, PMID:22207076, PMID:23300732, PMID:26278786 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfaip3 TNF alpha induced protein 3 multiple interactions ISO TNFAIP3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] CTD PMID:11880364 NCBI chr 1:14,401,103...14,416,369
Ensembl chr 1:14,402,913...14,412,807
JBrowse link
G Tnfsf10 TNF superfamily member 10 multiple interactions ISO [Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP7 protein; [Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP9 protein; [Dactinomycin co-treated with TNFSF10 protein] results in increased expression of AIFM1 protein CTD PMID:17707539 NCBI chr 2:113,008,008...113,026,899
Ensembl chr 2:113,007,549...113,026,899
JBrowse link
G Tnfsf9 TNF superfamily member 9 increases expression ISO Dactinomycin results in increased expression of TNFSF9 mRNA CTD PMID:21527772 NCBI chr 9:9,909,942...9,912,276
Ensembl chr 9:9,909,948...9,912,276
JBrowse link
G Top1 DNA topoisomerase I increases activity ISO Dactinomycin results in increased activity of TOP1 protein CTD PMID:2164630 NCBI chr 3:156,635,688...156,717,686
Ensembl chr 3:156,642,464...156,717,686
JBrowse link
G Tp53 tumor protein p53 multiple interactions
increases activity
increases expression
ISO Cadmium Chloride inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]; Cadmium inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]; Dactinomycin promotes the reaction [MRPL41 protein results in increased stability of and affects the localization of TP53 protein]; Dactinomycin results in increased expression of and affects the localization of TP53 protein; Dactinomycin results in increased expression of and results in increased activity of TP53 protein; Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]]
Dactinomycin results in increased activity of TP53 protein
Dactinomycin results in increased expression of TP53 protein; Dactinomycin results in increased expression of TP53 protein modified form
CTD PMID:10531375, PMID:12807743, PMID:12869419, PMID:12927789, PMID:16024796, PMID:17581298, PMID:20655369 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tp53i11 tumor protein p53 inducible protein 11 multiple interactions
decreases expression
ISO Dactinomycin inhibits the reaction [arsenic trioxide results in increased expression of TP53I11 mRNA]
Dactinomycin results in decreased expression of TP53I11 mRNA
CTD PMID:19333544 NCBI chr 3:82,081,838...82,097,064
Ensembl chr 3:82,081,906...82,097,056
JBrowse link
G Trpv6 transient receptor potential cation channel, subfamily V, member 6 multiple interactions ISO Dactinomycin inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of TRPV6 mRNA] CTD PMID:16362534 NCBI chr 4:70,918,631...70,934,291
Ensembl chr 4:70,918,632...70,934,295
JBrowse link
G Tuba4a tubulin, alpha 4A increases expression ISO Dactinomycin results in increased expression of TUBA4A mRNA CTD PMID:21527772 NCBI chr 9:82,415,599...82,419,918
Ensembl chr 9:82,415,605...82,419,288
JBrowse link
G Txnrd1 thioredoxin reductase 1 multiple interactions ISO Dactinomycin inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA]; Dactinomycin inhibits the reaction [sulforafan results in increased expression of TXNRD1 mRNA] CTD PMID:12663510, PMID:15652504 NCBI chr 7:26,946,124...26,984,400
Ensembl chr 7:26,946,125...26,984,400
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO Dactinomycin inhibits the reaction [IFNA1 protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [IFNB1 protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [IFNG protein results in increased expression of TYMP mRNA]; Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]; tanespimycin inhibits the reaction [Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]] CTD PMID:15937643, PMID:30796972 NCBI chr 7:130,342,481...130,347,845
Ensembl chr 7:130,342,483...130,347,587
JBrowse link
G Tyr tyrosinase multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [Quercetin results in increased activity of TYR protein]
Dactinomycin inhibits the reaction [Phenylephrine results in increased activity of TYR protein]
CTD PMID:14717847, PMID:15278367 NCBI chr 1:151,012,598...151,106,802
Ensembl chr 1:151,012,598...151,106,802
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 multiple interactions ISO Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of UBE2L3 mRNA] CTD PMID:26318284 NCBI chr11:88,047,186...88,088,477
Ensembl chr11:88,047,832...88,088,476
JBrowse link
G Uchl1 ubiquitin C-terminal hydrolase L1 multiple interactions EXP Dactinomycin inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein] CTD PMID:15545831 NCBI chr14:43,133,224...43,143,942
Ensembl chr14:43,133,218...43,143,973
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]
Dactinomycin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]
CTD PMID:10100995, PMID:12892526 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
G Vegfa vascular endothelial growth factor A multiple interactions ISO
EXP
Dactinomycin inhibits the reaction [Oxaliplatin results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of VEGFA mRNA]
Dactinomycin inhibits the reaction [Cobalt results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Estradiol results in increased expression of VEGFA mRNA alternative form]; Dactinomycin inhibits the reaction [Nickel results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA]
CTD PMID:8344219, PMID:10751333, PMID:11641398, PMID:16386082, PMID:18790786 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin multiple interactions ISO Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of VIM mRNA] CTD PMID:9044050 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Vmp1 vacuole membrane protein 1 multiple interactions
decreases expression
ISO [Dactinomycin co-treated with fludioxonil] results in decreased expression of VMP1 mRNA; Dactinomycin inhibits the reaction [Dehydroepiandrosterone results in increased expression of VMP1 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of VMP1 mRNA]
Dactinomycin results in decreased expression of VMP1 mRNA
CTD PMID:23052036, PMID:25969534 NCBI chr10:73,901,988...74,001,900
Ensembl chr10:73,902,837...74,001,895
JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO Dactinomycin results in decreased expression of XIAP protein CTD PMID:12430140 NCBI chr  X:128,409,425...128,455,786
Ensembl chr  X:128,409,472...128,453,000
JBrowse link
bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] CTD PMID:20581171 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]
CTD PMID:14609568, PMID:17177178, PMID:21381050, PMID:23656969, PMID:24762191, PMID:25582705, PMID:25648892, PMID:26520185, PMID:27704718, PMID:28694203, PMID:31302203, PMID:31706003 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression
EXP protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705, PMID:25933445 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607, PMID:26520185 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin increases expression EXP Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa4 annexin A4 decreases expression EXP Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 increases expression EXP Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa6 annexin A6 decreases expression EXP Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr10:40,320,581...40,375,605
Ensembl chr10:40,320,581...40,375,605
JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Areg amphiregulin increases expression ISO Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg1 arginase 1 increases expression ISO Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein CTD PMID:26345256, PMID:26526764 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Bleomycin results in increased expression of ATPIF1 protein CTD PMID:25933445 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Bleomycin results in decreased expression of ATP5O protein CTD PMID:29733421 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Bleomycin results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
CTD PMID:23656969, PMID:26093215, PMID:32278510 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
CTD PMID:23656969, PMID:24822179, PMID:26093215, PMID:26800624, PMID:32278510 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression
ISO
EXP
BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein
CTD PMID:10815900, PMID:15371238 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr10:63,197,367...63,240,447
Ensembl chr10:63,197,364...63,240,332
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G C1qb complement C1q B chain increases expression ISO Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G Cald1 caldesmon 1 increases expression EXP Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calml3 calmodulin-like 3 decreases expression EXP Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Calr calreticulin increases expression EXP Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin increases expression EXP Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression EXP Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression EXP Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
Bleomycin results in increased activity of CASP3 protein
CTD PMID:15371238, PMID:22687607, PMID:23656969, PMID:24822179, PMID:26093215, PMID:26800624 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP
ISO
Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA
Bleomycin results in increased activity of CASP9 protein
CTD PMID:15371238, PMID:22687607, PMID:26800624 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression EXP Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase increases response to substance
multiple interactions
decreases activity
increases expression
ISO
EXP
CAT protein results in increased susceptibility to Bleomycin
tripterine inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]
CTD PMID:8317554, PMID:10751631, PMID:23570914, PMID:26768587 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression EXP Bleomycin results in decreased expression of CAV1 protein CTD PMID:25933445 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression EXP Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cckar cholecystokinin A receptor decreases expression EXP Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases expression
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
Bleomycin results in decreased expression of CCL11 mRNA
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:16314464, PMID:29720568 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL12 mRNA
Bleomycin results in decreased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
CTD PMID:28434932, PMID:29720568 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256, PMID:29175452 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
Bleomycin results in decreased expression of CCL2 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
CTD PMID:15541506, PMID:16314464, PMID:17177178, PMID:19147827, PMID:26209236, PMID:26520185, PMID:26526764, PMID:29720568 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL3 mRNA
Bleomycin results in decreased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
CTD PMID:26520185, PMID:29720568 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 increases expression ISO Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein
CTD PMID:19080365, PMID:26817844, PMID:28434932 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression
decreases response to substance
ISO CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
Bleomycin results in increased expression of CCR2 mRNA
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:14609568, PMID:29033951
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression ISO Bleomycin affects the expression of CCR5 mRNA CTD PMID:26345256 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein
CTD PMID:28300665, PMID:28694203 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256, PMID:29720568 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
increases response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CEBPB mRNA
CEBPB protein results in increased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:17177178, PMID:21998664 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfl1 cofilin 1 increases expression EXP Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions
ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein]
CTD PMID:24933654 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Ckb creatine kinase B increases expression EXP Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression EXP Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:16,170,585...16,196,691
Ensembl chr  X:16,050,780...16,196,789
JBrowse link
G Cldn4 claudin 4 increases expression ISO Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression EXP Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr 9:19,121,676...19,372,673
Ensembl chr 9:19,121,677...19,372,673
JBrowse link
G Cltc clathrin heavy chain decreases expression EXP Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression
ISO
EXP
[Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
CTD PMID:12003776, PMID:14609568, PMID:17434272, PMID:19147827, PMID:24762191, PMID:25933445, PMID:26093215, PMID:26345256, PMID:28300665, PMID:28726637, PMID:29033951, PMID:31302203 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of COL1A2 mRNA
Bleomycin results in decreased expression of COL1A2 protein
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
CTD PMID:19147827, PMID:25933445 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression
multiple interactions
increases expression
EXP
ISO
Bleomycin results in decreased expression of COL3A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
CTD PMID:25933445, PMID:26817844, PMID:28726637 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP Bleomycin results in decreased expression of COL5A1 protein CTD PMID:25933445 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
ISO tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
decreases expression
ISO Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA
CTD PMID:18684396, PMID:29720568 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression EXP Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctsa cathepsin A affects expression ISO Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 3:161,298,750...161,304,627
Ensembl chr 3:161,298,962...161,304,625
JBrowse link
G Ctsb cathepsin B affects expression ISO Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsh cathepsin H affects expression ISO Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
ISO Bleomycin results in increased expression of CXCL10 mRNA
Bleomycin results in decreased expression of CXCL10 mRNA
CTD PMID:26345256, PMID:29720568 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion
ISO Bleomycin results in increased expression of CXCL2 protein
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
CTD PMID:18684396, PMID:22687607, PMID:26520185, PMID:26600069 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein] CTD PMID:26600069 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression EXP Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Des desmin increases expression EXP Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP
ISO
Bleomycin results in increased expression of DLD protein CTD PMID:25933445, PMID:29733421 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egr1 early growth response 1 increases expression
affects expression
multiple interactions
ISO Bleomycin results in increased expression of EGR1 mRNA
Bleomycin affects the expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
CTD PMID:19147827, PMID:26345256 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 affects expression ISO Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Ehd1 EH-domain containing 1 decreases expression EXP Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 1:77,847,599...77,865,870
Ensembl chr 1:77,847,600...77,865,870
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eln elastin increases expression ISO Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Epx eosinophil peroxidase increases expression EXP Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Ezr ezrin decreases expression EXP Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression
EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein
CTD PMID:23656969 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Faslg Fas ligand increases expression ISO Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions
EXP Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
CTD PMID:25582705 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of FN1 protein
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]
CTD PMID:25071917, PMID:25933445, PMID:26345256, PMID:26817844, PMID:28300665, PMID:31302203 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of FOS protein CTD PMID:12003776 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression EXP Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions
ISO Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]
CTD PMID:28726637 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression EXP Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression EXP Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr 1:225,096,558...225,116,384
Ensembl chr 1:225,096,598...225,116,378
JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]
CTD PMID:29033951 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression
ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gda guanine deaminase decreases expression EXP Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression EXP Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin decreases expression EXP Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP Bleomycin results in decreased activity of GSR protein
tripterine inhibits the reaction [Bleomycin results in decreased activity of GSR protein]
CTD PMID:26768587 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G H1f0 H1 histone family, member 0 affects expression EXP Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression EXP Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Bleomycin affects the expression of HBB protein CTD PMID:25933445 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases expression
increases secretion
EXP
ISO
Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]
Bleomycin results in increased expression of HGF mRNA
Bleomycin results in increased secretion of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
CTD PMID:16115399, PMID:22687607, PMID:29408570 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bg histone cluster 1, H2bg decreases expression EXP Bleomycin results in decreased expression of HIST1H2BG protein CTD PMID:25933445 NCBI chr17:43,817,316...43,817,717
Ensembl chr17:43,817,378...43,817,720
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
EXP
ISO
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD PMID:25582705, PMID:32278510 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of HMOX1 protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; tripterine inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
CTD PMID:16317386, PMID:26093215, PMID:26768587 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression EXP Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 3:62,481,222...62,491,356
Ensembl chr 3:62,481,323...62,487,227
JBrowse link
G Hpx hemopexin increases expression EXP Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Bleomycin results in increased expression of HSPA5 protein CTD PMID:25933445 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO
Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445, PMID:29733421 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A decreases expression EXP Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951, PMID:29720568 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
decreases expression
ISO Bleomycin results in increased expression of IFNG mRNA
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG mRNA
CTD PMID:11350791, PMID:25071917, PMID:26209236, PMID:29408570 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 increases expression ISO Bleomycin results in increased expression of IL10 protein CTD PMID:29175452 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression ISO Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression ISO Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 4:98,049,195...98,141,562
Ensembl chr 4:98,052,842...98,141,482
JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions
ISO IL13 gene mutant form results in decreased susceptibility to Bleomycin
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
CTD PMID:15322207 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1A protein
CTD PMID:8317554, PMID:29175452 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
affects expression
increases expression
ISO
EXP
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin affects the expression of IL1B mRNA
IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
CTD PMID:8317554, PMID:8473757, PMID:16317386, PMID:17035056, PMID:17118201, PMID:17177178, PMID:19147827, PMID:22687607, PMID:26093215, PMID:26520185, PMID:26526764, PMID:26600069, PMID:27704718, PMID:28300665, PMID:28694203 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases expression
affects response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of IL4 mRNA
IL4 protein affects the susceptibility to Bleomycin
IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
IL4 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:11554783, PMID:12574379, PMID:15322207 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of IL6 protein
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
CTD PMID:17035056, PMID:18684396, PMID:23656969, PMID:25071917, PMID:26093215, PMID:26209236, PMID:26520185, PMID:28300665 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression EXP Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of JUN protein CTD PMID:12003776 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
EXP Bleomycin results in decreased expression of KEAP1 protein
tripterine inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]
CTD PMID:26768587 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions
ISO Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
CTD PMID:29733421 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kl Klotho decreases expression ISO Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt19 keratin 19 decreases expression EXP Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression EXP Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lep leptin increases expression ISO Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals3 galectin 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of LGALS3 protein
NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]
CTD PMID:26526764 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lmna lamin A/C increases expression EXP Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G LOC100362172 LRRGT00112-like increases expression EXP Bleomycin results in increased expression of UQCRHL protein CTD PMID:25933445 NCBI chr17:22,655,291...22,678,983
Ensembl chr17:22,655,999...22,678,253
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form]
CTD PMID:31302203 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression EXP Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions
EXP
ISO
Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein
CTD PMID:25933445, PMID:29733421 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance ISO MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions
increases phosphorylation
ISO Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein
CTD PMID:22687607 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir100 microRNA 100 decreases expression EXP Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
JBrowse link
G Mir101-2 microRNA 101-2 decreases expression EXP
ISO
Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445, PMID:28726637 NCBI chr 1:247,263,723...247,263,819
Ensembl chr 1:247,263,723...247,263,819
JBrowse link
G Mir101a microRNA 101a multiple interactions
decreases expression
ISO
EXP
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
Bleomycin results in decreased expression of MIR101A mRNA
CTD PMID:25933445, PMID:28726637 NCBI chr 5:120,168,437...120,168,511
Ensembl chr 5:120,168,433...120,168,515
JBrowse link
G Mir106b microRNA 106b affects expression EXP Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr12:19,307,752...19,307,833
Ensembl chr12:19,307,752...19,307,833
JBrowse link
G Mir107 microRNA 107 decreases expression EXP Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr 1:253,128,250...253,128,336
Ensembl chr 1:253,128,250...253,128,336
JBrowse link
G Mir10a microRNA 10a decreases expression EXP Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr10:84,165,950...84,166,059
Ensembl chr10:84,165,950...84,166,059
JBrowse link
G Mir10b microRNA 10b decreases expression EXP Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 3:61,647,978...61,648,086
Ensembl chr 3:61,647,978...61,648,086
JBrowse link
G Mir1224 microRNA 1224 increases expression EXP Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr11:83,992,628...83,992,712
Ensembl chr11:83,992,628...83,992,712
JBrowse link
G Mir1249 microRNA 1249 affects expression EXP Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr 7:125,861,192...125,861,311
Ensembl chr 7:125,861,192...125,861,311
JBrowse link
G Mir125a microRNA 125a affects expression EXP Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Mir126b microRNA 126b decreases expression EXP Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mir130a microRNA 130a decreases expression EXP Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124
JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression EXP Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:2,052,478...2,052,564 JBrowse link
G Mir133b microRNA 133b decreases expression EXP Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 9:26,795,649...26,795,732
Ensembl chr 9:26,795,649...26,795,732
JBrowse link
G Mir140 microRNA 140 affects expression EXP Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr19:39,608,951...39,609,049
Ensembl chr19:39,608,951...39,609,049
JBrowse link
G Mir141 microRNA 141 affects expression EXP Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 4:157,236,346...157,236,439
Ensembl chr 4:157,236,346...157,236,439
JBrowse link
G Mir142 microRNA 142 decreases expression
increases expression
EXP Bleomycin results in decreased expression of MIR142 mRNA
Bleomycin results in increased expression of MIR142 mRNA
CTD PMID:25933445 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir143 microRNA 143 decreases expression EXP Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:56,971,273...56,971,377
Ensembl chr18:56,971,273...56,971,377
JBrowse link
G Mir144 microRNA 144 decreases expression EXP Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir145 microRNA 145 decreases expression EXP Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir146a microRNA 146a affects expression EXP Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir146b microRNA 146b increases expression EXP Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir148b microRNA 148b decreases expression EXP Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr 7:144,912,038...144,912,134
Ensembl chr 7:144,912,038...144,912,134
JBrowse link
G Mir150 microRNA 150 affects expression EXP Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 1:101,115,974...101,116,058
Ensembl chr 1:101,115,974...101,116,058
JBrowse link
G Mir151 microRNA 151 decreases expression EXP Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr 7:114,485,547...114,485,643 JBrowse link
G Mir152 microRNA 152 decreases expression EXP Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr10:84,719,319...84,719,403
Ensembl chr10:84,719,319...84,719,403
JBrowse link
G Mir15b microRNA 15b affects expression EXP Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir16 microRNA 16 decreases expression EXP Bleomycin results in decreased expression of MIR16 mRNA CTD PMID:25933445 NCBI chr 2:165,606,072...165,606,166
Ensembl chr 2:165,606,072...165,606,166
JBrowse link
G Mir17 microRNA 17 affects expression EXP Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr15:100,179,879...100,179,962
Ensembl chr15:100,179,879...100,179,962
JBrowse link
G Mir181c microRNA 181c decreases expression EXP Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir181d microRNA 181d decreases expression EXP Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr19:25,290,051...25,290,133
Ensembl chr19:25,290,051...25,290,133
JBrowse link
G Mir183 microRNA 183 affects expression EXP Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir186 microRNA 186 decreases expression EXP Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir188 microRNA 188 affects expression EXP Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:16,110,270...16,110,349
Ensembl chr  X:16,110,270...16,110,349
JBrowse link
G Mir18a microRNA 18a increases expression EXP Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr15:100,180,015...100,180,110
Ensembl chr15:100,180,015...100,180,110
JBrowse link
G Mir193 microRNA 193 decreases expression EXP Bleomycin results in decreased expression of MIR193 mRNA CTD PMID:25933445 NCBI chr10:67,065,896...67,065,981 JBrowse link
G Mir195 microRNA 195 decreases expression EXP Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr10:56,845,301...56,845,387
Ensembl chr10:56,845,301...56,845,387
JBrowse link
G Mir199a2 microRNA 199a-2 affects expression EXP Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr13:80,125,487...80,125,596
Ensembl chr13:80,125,487...80,125,596
JBrowse link
G Mir19a microRNA 19a affects expression EXP Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir200a microRNA 200a decreases expression EXP Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir200b microRNA 200b decreases expression EXP Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir200c microRNA 200c decreases expression EXP Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 4:157,236,786...157,236,854 JBrowse link
G Mir204 microRNA 204 decreases expression EXP Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir20a microRNA 20a affects expression EXP Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr15:100,180,334...100,180,418
Ensembl chr15:100,180,334...100,180,418
JBrowse link
G Mir20b microRNA 20b affects expression EXP Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:140,117,518...140,117,589
Ensembl chr  X:140,117,518...140,117,589
JBrowse link
G Mir21 microRNA 21 increases expression EXP Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir210 microRNA 210 decreases expression EXP Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mir211 microRNA 211 affects expression EXP Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 1:125,042,119...125,042,224
Ensembl chr 1:125,042,119...125,042,224
JBrowse link
G Mir212 microRNA 212 affects expression EXP Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr10:62,014,702...62,014,812
Ensembl chr10:62,014,702...62,014,812
JBrowse link
G Mir22 microRNA 22 affects expression EXP Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr10:62,299,592...62,299,686
Ensembl chr10:62,299,592...62,299,686
JBrowse link
G Mir221 microRNA 221 decreases expression EXP Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir222 microRNA 222 decreases expression EXP Bleomycin results in decreased expression of MIR222 mRNA CTD PMID:25933445 NCBI chr  X:3,683,919...3,684,021
Ensembl chr  X:3,683,919...3,684,021
JBrowse link
G Mir223 microRNA 223 affects expression EXP Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir23a microRNA 23a decreases expression EXP Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr19:25,318,582...25,318,656
Ensembl chr19:25,318,582...25,318,656
JBrowse link
G Mir23b microRNA 23b decreases expression EXP Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr17:823,222...823,318
Ensembl chr17:823,222...823,318
JBrowse link
G Mir24-2 microRNA 24-2 decreases expression EXP Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr19:25,318,863...25,318,970
Ensembl chr19:25,318,863...25,318,970
JBrowse link
G Mir25 microRNA 25 affects expression EXP Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr12:19,307,340...19,307,423
Ensembl chr12:19,307,340...19,307,423
JBrowse link
G Mir26a microRNA 26a decreases expression EXP Bleomycin results in decreased expression of MIR26A mRNA CTD PMID:25933445 NCBI chr 8:127,714,441...127,714,530
Ensembl chr 8:127,714,441...127,714,530
JBrowse link
G Mir26b microRNA 26b decreases expression EXP Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 9:81,675,275...81,675,359
Ensembl chr 9:81,675,275...81,675,359
JBrowse link
G Mir27a microRNA 27a decreases expression EXP Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir27b microRNA 27b decreases expression EXP Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr17:823,461...823,557
Ensembl chr17:823,461...823,557
JBrowse link
G Mir28 microRNA 28 decreases expression EXP Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Mir290 microRNA 290 increases expression EXP Bleomycin results in increased expression of MIR290 mRNA CTD PMID:25933445 NCBI chr 1:64,538,705...64,538,785
Ensembl chr 1:64,538,705...64,538,785
JBrowse link
G Mir296 microRNA 296 affects expression EXP Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir2985 microRNA 2985 affects expression EXP Bleomycin affects the expression of MIR2985 mRNA CTD PMID:25933445 NCBI chr 2:179,591,312...179,591,421
Ensembl chr 2:179,591,312...179,591,421
JBrowse link
G Mir29a microRNA 29a decreases expression EXP Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir301a microRNA 301a affects expression EXP Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
G Mir30a microRNA 30a decreases expression EXP Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir30b microRNA 30b decreases expression EXP Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression EXP Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 9:29,562,376...29,562,459
Ensembl chr 9:29,562,376...29,562,459
JBrowse link
G Mir30d microRNA 30d decreases expression EXP Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr 7:109,286,463...109,286,544
Ensembl chr 7:109,286,463...109,286,544
JBrowse link
G Mir30e microRNA 30e decreases expression EXP Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 5:139,702,872...139,702,963
Ensembl chr 5:139,702,872...139,702,963
JBrowse link
G Mir31 microRNA 31 decreases expression EXP Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir32 microRNA 32 increases expression EXP Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 5:73,934,255...73,934,324
Ensembl chr 5:73,934,255...73,934,324
JBrowse link
G Mir320a microRNA 320a decreases expression EXP Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
JBrowse link
G Mir322 microRNA 322 decreases expression EXP Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:158,148,161...158,148,255
Ensembl chr  X:158,148,161...158,148,255
JBrowse link
G Mir324 microRNA 324 affects expression EXP Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Mir326 microRNA 326 decreases expression EXP Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 1:164,518,401...164,518,495
Ensembl chr 1:164,518,401...164,518,495
JBrowse link
G Mir328 microRNA 328 affects expression EXP Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr19:37,263,199...37,263,282
Ensembl chr19:37,263,199...37,263,282
JBrowse link
G Mir33 microRNA 33 decreases expression EXP Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr 7:123,431,612...123,431,680
Ensembl chr 7:123,431,612...123,431,680
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir331 microRNA 331 decreases expression EXP Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir340-1 microRNA mir-340-1 increases expression EXP Bleomycin results in increased expression of MIR340-1 mRNA CTD PMID:25933445 Ensembl chr10:35,558,983...35,559,080
Ensembl chr10:35,558,983...35,559,080
JBrowse link
G Mir342 microRNA 342 decreases expression EXP Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
JBrowse link
G Mir345 microRNA 345 decreases expression EXP Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr 6:132,748,968...132,749,063
Ensembl chr 6:132,748,968...132,749,063
JBrowse link
G Mir347 microRNA mir-347 decreases expression EXP Bleomycin results in decreased expression of MIR347 mRNA CTD PMID:25933445
G Mir3473 microRNA 3473 increases expression EXP Bleomycin results in increased expression of MIR3473 mRNA CTD PMID:25933445 NCBI chr13:44,719,335...44,719,401
Ensembl chr13:44,719,335...44,719,401
JBrowse link
G Mir34a microRNA 34a affects expression EXP Bleomycin affects the expression of MIR34A mRNA CTD PMID:25933445 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir34b microRNA 34b decreases expression EXP Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Bleomycin results in decreased expression of MIR352 mRNA CTD PMID:25933445
G Mir3545 microRNA 3545 decreases expression EXP Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Mir3573 microRNA 3573 decreases expression EXP Bleomycin results in decreased expression of MIR3573 mRNA CTD PMID:25933445 NCBI chr  X:68,892,972...68,893,043
Ensembl chr  X:68,892,972...68,893,043
JBrowse link
G Mir3584 microRNA 3584 affects expression EXP Bleomycin affects the expression of MIR3584 mRNA CTD PMID:25933445 NCBI chr 1:271,275,895...271,275,975
Ensembl chr 1:271,275,895...271,275,975
JBrowse link
G Mir361 microRNA 361 decreases expression EXP Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:84,708,911...84,708,980
Ensembl chr  X:84,708,911...84,708,980
JBrowse link
G Mir365b microRNA 365b decreases expression EXP Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr10:67,079,796...67,079,881
Ensembl chr10:67,079,796...67,079,881
JBrowse link
G Mir374b microRNA 374b decreases expression EXP Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:74,443,648...74,443,715
Ensembl chr  X:74,443,648...74,443,715
JBrowse link
G Mir375 microRNA 375 decreases expression EXP Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 9:82,161,716...82,161,790
Ensembl chr 9:82,161,716...82,161,790
JBrowse link
G Mir378 microRNA 378 decreases expression EXP Bleomycin results in decreased expression of MIR378 mRNA CTD PMID:25933445 NCBI chr18:56,726,150...56,726,214 JBrowse link
G Mir409 microRNA 409 affects expression EXP Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr 6:133,893,419...133,893,495 JBrowse link
G Mir423 microRNA 423 decreases expression EXP Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr10:63,098,366...63,098,444
Ensembl chr10:63,098,360...63,098,453
JBrowse link
G Mir425 microRNA 425 affects expression EXP Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 8:117,354,821...117,354,903
Ensembl chr 8:117,354,821...117,354,903
JBrowse link
G Mir429 microRNA 429 decreases expression EXP Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 5:173,488,331...173,488,415
Ensembl chr 5:173,488,331...173,488,415
JBrowse link
G Mir449a microRNA 449a affects expression EXP Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691
JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:158,153,377...158,153,467
Ensembl chr  X:158,153,377...158,153,467
JBrowse link
G Mir451a microRNA 451a decreases expression EXP Bleomycin results in decreased expression of MIR451A mRNA CTD PMID:25933445 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Mir494 microRNA 494 decreases expression EXP Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr 6:133,864,370...133,864,452
Ensembl chr 6:133,864,369...133,864,453
JBrowse link
G Mir497 microRNA 497 decreases expression EXP Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
JBrowse link
G Mir500 microRNA 500 affects expression EXP Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:16,121,332...16,121,411
Ensembl chr  X:16,121,322...16,121,413
JBrowse link
G Mir503 microRNA 503 decreases expression EXP Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir532 microRNA 532 affects expression EXP Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:16,109,870...16,109,948
Ensembl chr  X:16,109,870...16,109,948
JBrowse link
G Mir542 microRNA 542 decreases expression EXP Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:158,152,146...158,152,224
Ensembl chr  X:158,152,146...158,152,224
JBrowse link
G Mir6215 microRNA 6215 decreases expression EXP Bleomycin results in decreased expression of MIR6215 mRNA CTD PMID:25933445 NCBI chr 5:158,060,994...158,061,060
Ensembl chr 5:158,060,994...158,061,060
JBrowse link
G Mir6216 microRNA 6216 decreases expression EXP Bleomycin results in decreased expression of MIR6216 mRNA CTD PMID:25933445 NCBI chr 3:46,361,908...46,361,985
Ensembl chr 3:46,361,908...46,361,985
JBrowse link
G Mir6328 microRNA 6328 affects expression EXP Bleomycin affects the expression of MIR6328 mRNA CTD PMID:25933445 NCBI chr20:3,394,813...3,394,909
Ensembl chr20:3,394,813...3,394,909
JBrowse link
G Mir652 microRNA 652 affects expression EXP Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:114,002,534...114,002,614
Ensembl chr  X:114,002,534...114,002,614
JBrowse link
G Mir93 microRNA 93 affects expression EXP Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mir96 microRNA 96 affects expression EXP Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mir98 microRNA 98 decreases expression EXP Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:21,583,875...21,583,982
Ensembl chr  X:21,583,875...21,583,982
JBrowse link
G Mir99a microRNA 99a decreases expression EXP Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr11:16,052,153...16,052,233
Ensembl chr11:16,052,153...16,052,233
JBrowse link
G Mir99b microRNA 99b decreases expression EXP Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr 1:59,704,216...59,704,285
Ensembl chr 1:59,704,216...59,704,285
JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr17:16,419,980...16,420,077
Ensembl chr17:16,419,980...16,420,077
JBrowse link
G Mirlet7i microRNA let-7i decreases expression EXP Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; tripterine inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
CTD PMID:23656969, PMID:26345256, PMID:26768587, PMID:29175452 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; tripterine inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
CTD PMID:23656969, PMID:26526764, PMID:26768587, PMID:28300665, PMID:28694203 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity
ISO
EXP
pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Bleomycin results in increased expression of MPO protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein]
CTD PMID:16317386, PMID:17035056, PMID:17118201, PMID:26093215 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Msn moesin decreases expression EXP Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]
CTD PMID:18684396, PMID:26093215 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance ISO MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh11 myosin heavy chain 11 decreases expression EXP Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl12b myosin light chain 12B increases expression EXP Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr 9:119,307,168...119,321,500
Ensembl chr 9:119,307,176...119,321,500
JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
JBrowse link
G Myl6l myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like increases expression EXP Bleomycin results in increased expression of MYL6L protein CTD PMID:25933445
G Myo1c myosin 1C decreases expression EXP Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr10:63,803,311...63,819,614
Ensembl chr10:63,803,309...63,819,614
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions
increases expression
ISO MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr&nb