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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
decreases response to substance multiple interactions |
ISO EXP |
ABCB1 protein results in decreased susceptibility to Dactinomycin Dactinomycin inhibits the reaction [[Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Dactinomycin inhibits the reaction [[Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] which results in increased uptake of (N-5-(4-nitrobenzofurazan-7-yl)lysyl(8))cyclosporine]; Dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1A mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Dactinomycin inhibits the reaction [tetrabromobisphenol A results in increased expression of and results in increased activity of ABCB1A protein]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein] Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 mRNA]; Dactinomycin inhibits the reaction [Estradiol results in increased expression of ABCB1 protein]; Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 mRNA]; Dactinomycin inhibits the reaction [Progesterone results in increased expression of ABCB1 protein]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCB1 mRNA] |
CTD |
PMID:1967174 PMID:11455017 PMID:15725475 PMID:18474546 PMID:19813763 PMID:20410605 PMID:30830211 More...
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Abcb1b |
ATP-binding cassette, subfamily B (MDR/TAP), member 1B |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [coptisine results in increased expression of ABCB1B mRNA] |
CTD |
PMID:20410605 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
decreases response to substance |
ISO EXP |
ABCC1 protein results in decreased susceptibility to Dactinomycin |
CTD |
PMID:11455017 PMID:12067707 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
decreases response to substance multiple interactions |
EXP ISO |
ABCC2 protein results in decreased susceptibility to Dactinomycin Dactinomycin inhibits the reaction [Bucladesine results in increased expression of ABCC2 mRNA] Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of ABCC2 mRNA] |
CTD |
PMID:11408547 PMID:11455017 PMID:26049102 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Daunorubicin results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [Doxorubicin results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [Mitoxantrone results in increased expression of ABCG2 mRNA]; Dactinomycin inhibits the reaction [SHH protein alternative form results in increased expression of ABCG2 protein]; Dactinomycin inhibits the reaction [Sulfasalazine results in increased expression of ABCG2 mRNA] |
CTD |
PMID:20019844 PMID:21625222 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Abhd3 |
abhydrolase domain containing 3, phospholipase |
increases expression |
ISO |
Dactinomycin results in increased expression of ABHD3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr18:1,723,203...1,778,488
Ensembl chr18:1,720,718...1,803,428
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Aldosterone results in increased activity of ACE protein]; Dactinomycin inhibits the reaction [Aldosterone results in increased expression of ACE mRNA] |
CTD |
PMID:15932931 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Acsl6 |
acyl-CoA synthetase long-chain family member 6 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [4-(3-(2-propyl-3-hydroxy-4-acetyl)phenoxy)propyloxyphenoxy acetic acid results in increased expression of ACSL6 mRNA] |
CTD |
PMID:10585473 |
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NCBI chr10:38,439,914...38,501,182
Ensembl chr10:38,440,080...38,498,757
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G |
Adam9 |
ADAM metallopeptidase domain 9 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased expression of ADAM9 protein] |
CTD |
PMID:17018608 |
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NCBI chr16:67,022,538...67,101,647
Ensembl chr16:67,022,655...67,100,917
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G |
Adrb2 |
adrenoceptor beta 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of ADRB2 protein]; Dactinomycin inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA]; Dactinomycin inhibits the reaction [Formoterol Fumarate affects the expression of ADRB2 mRNA] |
CTD |
PMID:22483689 PMID:24705868 |
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NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512
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G |
Agrp |
agouti related neuropeptide |
decreases expression multiple interactions |
ISO |
Dactinomycin results in decreased expression of AGRP mRNA Dactinomycin inhibits the reaction [bisphenol A results in increased expression of AGRP mRNA] |
CTD |
PMID:32575098 |
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NCBI chr19:33,447,992...33,523,068
Ensembl chr19:33,447,992...33,449,584
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G |
Agt |
angiotensinogen |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [Amiodarone results in increased expression of AGT mRNA] Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA]; Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA]; Dactinomycin promotes the reaction [Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]]; Dactinomycin promotes the reaction [Valsartan inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]] |
CTD |
PMID:16705055 PMID:17214612 PMID:19292980 PMID:23288202 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA] ARNT protein promotes the reaction [Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in decreased expression of AHR protein]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein] |
CTD |
PMID:9145908 PMID:16226227 PMID:25637755 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Aicda |
activation-induced cytidine deaminase |
multiple interactions |
ISO |
[Dactinomycin co-treated with Alpha-Amanitin] inhibits the reaction [Estradiol results in increased expression of AICDA mRNA] |
CTD |
PMID:19139166 |
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NCBI chr 4:155,774,132...155,783,972
Ensembl chr 4:155,774,132...155,783,972
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G |
Aifm1 |
apoptosis inducing factor, mitochondria associated 1 |
multiple interactions |
ISO |
[Dactinomycin co-treated with TNFSF10 protein] results in increased expression of AIFM1 protein |
CTD |
PMID:17707539 |
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NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions |
ISO |
PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein] PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein] |
CTD |
PMID:14640974 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alpi |
alkaline phosphatase, intestinal |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Fish Oils results in increased activity of ALPI protein] |
CTD |
PMID:15599000 |
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NCBI chr 9:87,773,411...87,776,877
Ensembl chr 9:87,773,411...87,776,877
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G |
Alx3 |
ALX homeobox 3 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Folic Acid results in increased expression of ALX3 mRNA] |
CTD |
PMID:20534379 |
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NCBI chr 2:195,231,197...195,241,609
Ensembl chr 2:195,231,197...195,241,609
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G |
Aoc1 |
amine oxidase, copper containing 1 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Epinephrine results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of AOC1 protein]; Dactinomycin inhibits the reaction [Terbutaline results in increased activity of AOC1 protein] |
CTD |
PMID:2860926 PMID:6218830 |
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NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840
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G |
Aqp1 |
aquaporin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [cobaltous chloride results in increased expression of AQP1 mRNA] |
CTD |
PMID:22415096 |
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NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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G |
Arhgdib |
Rho GDP dissociation inhibitor beta |
increases expression |
ISO |
Dactinomycin results in increased expression of ARHGDIB mRNA |
CTD |
PMID:21527772 |
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NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
ISO |
ARNT protein promotes the reaction [Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased degradation of AHR protein]] |
CTD |
PMID:16226227 |
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NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Atf4 |
activating transcription factor 4 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Bortezomib results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Bortezomib results in increased expression of ATF4 protein]; Dactinomycin inhibits the reaction [Fenretinide results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Fenretinide results in increased expression of ATF4 protein]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of ATF4 protein] |
CTD |
PMID:20022965 |
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NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Ethanol results in increased expression of ATG7 protein] |
CTD |
PMID:24095927 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions |
ISO |
Dactinomycin results in decreased expression of and results in increased phosphorylation of ATM protein |
CTD |
PMID:31226288 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Avp |
arginine vasopressin |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [[Phenylephrine co-treated with Adenosine Triphosphate] results in increased secretion of AVP protein] |
CTD |
PMID:11102496 |
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NCBI chr 3:117,793,447...117,805,091
Ensembl chr 3:117,793,457...117,795,425
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G |
Axl |
Axl receptor tyrosine kinase |
increases expression |
ISO |
Dactinomycin results in increased expression of AXL mRNA |
CTD |
PMID:21527772 |
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NCBI chr 1:81,265,656...81,296,278
Ensembl chr 1:81,265,088...81,296,265
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G |
Bag3 |
BAG cochaperone 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of BAG3 mRNA] |
CTD |
PMID:22020323 |
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NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
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G |
Bak1 |
BCL2-antagonist/killer 1 |
multiple interactions |
EXP ISO |
Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAK1 mRNA] Dactinomycin promotes the reaction [BAK1 protein binds to BAK1 protein] |
CTD |
PMID:21281706 PMID:26670606 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
increases expression multiple interactions |
ISO EXP |
Dactinomycin results in increased expression of BAX mRNA; Dactinomycin results in increased expression of BAX protein Dactinomycin promotes the reaction [BAX protein binds to BAX protein] Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of BAX mRNA] Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of BAX protein]] |
CTD |
PMID:10760829 PMID:12927789 PMID:21281706 PMID:21527772 PMID:26670606 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bbc3 |
Bcl-2 binding component 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of BBC3 mRNA; Dactinomycin results in increased expression of BBC3 protein |
CTD |
PMID:17581298 |
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NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO |
BCL2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; Dactinomycin inhibits the reaction [IL1B results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [Paclitaxel results in increased phosphorylation of BCL2 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of BCL2 protein]; Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in decreased expression of BCL2 protein]] Dactinomycin results in decreased expression of BCL2 mRNA; Dactinomycin results in decreased expression of BCL2 protein |
CTD |
PMID:11726273 PMID:11880364 PMID:12927789 PMID:16492401 PMID:17581298 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl2a1 |
BCL2-related protein A1 |
multiple interactions |
ISO |
BCL2A1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
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NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998
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G |
Bcl2l1 |
Bcl2-like 1 |
decreases expression multiple interactions increases expression |
ISO |
Dactinomycin results in decreased expression of BCL2L1 protein Dexamethasone inhibits the reaction [Dactinomycin results in increased expression of BCL2L1 protein] Dactinomycin results in increased expression of BCL2L1 protein; Dactinomycin results in increased expression of BCL2L1 protein alternative form |
CTD |
PMID:9326359 PMID:12430140 PMID:15592511 |
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NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
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G |
Bcl2l11 |
Bcl2-like 11 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of BCL2L11 mRNA] |
CTD |
PMID:16166651 |
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NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions decreases expression |
EXP |
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of BDNF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of BDNF mRNA] Dactinomycin results in decreased expression of BDNF mRNA |
CTD |
PMID:22982731 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Becn1 |
beclin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Ethanol results in increased expression of BECN1 protein] |
CTD |
PMID:24095927 |
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NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
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G |
Bid |
BH3 interacting domain death agonist |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [vorinostat results in increased cleavage of BID protein] Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of BID mRNA] |
CTD |
PMID:11535817 PMID:16166651 |
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NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
multiple interactions |
ISO |
BIRC3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
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NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Bnip3 |
BCL2 interacting protein 3 |
multiple interactions |
ISO |
[Dactinomycin co-treated with TNF protein] results in increased expression of BNIP3 mRNA; Dactinomycin inhibits the reaction [Ethanol results in increased expression of BNIP3 protein]; Dactinomycin inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein] |
CTD |
PMID:11592958 PMID:19442826 PMID:24095927 |
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NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359
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G |
Bsdc1 |
BSD domain containing 1 |
increases expression |
ISO |
Dactinomycin results in increased expression of BSDC1 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 5:141,798,918...141,827,091
Ensembl chr 5:141,798,981...141,827,092
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G |
Btrc |
beta-transducin repeat containing E3 ubiquitin protein ligase |
multiple interactions |
ISO |
Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax co-treated with hydroquinone] results in decreased expression of BTRC mRNA]; Dactinomycin promotes the reaction [[WEHI-539 co-treated with venetoclax] results in decreased expression of BTRC mRNA] |
CTD |
PMID:35561756 |
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NCBI chr 1:244,210,299...244,380,126
Ensembl chr 1:244,210,314...244,376,721
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G |
C1qbp |
complement C1q binding protein |
decreases response to substance |
ISO |
C1QBP protein results in decreased susceptibility to Dactinomycin |
CTD |
PMID:25354864 |
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NCBI chr10:55,699,954...55,704,605
Ensembl chr10:55,699,954...55,704,649
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G |
Cacna1g |
calcium voltage-gated channel subunit alpha1 G |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1G mRNA] |
CTD |
PMID:19292980 |
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NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752
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G |
Cacna1h |
calcium voltage-gated channel subunit alpha1 H |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CACNA1H mRNA] |
CTD |
PMID:19292980 |
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NCBI chr10:14,390,104...14,448,204
Ensembl chr10:14,390,113...14,448,376
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G |
Casp2 |
caspase 2 |
increases cleavage |
ISO |
Dactinomycin results in increased cleavage of CASP2 protein |
CTD |
PMID:10663630 |
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NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
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G |
Casp3 |
caspase 3 |
multiple interactions increases activity decreases expression |
ISO EXP |
[TNF co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP3 protein; Dactinomycin inhibits the reaction [Biological Products results in increased expression of CASP3 mRNA]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP3 protein] Dactinomycin results in increased cleavage of and results in increased activity of CASP3 protein [Dactinomycin co-treated with TNF protein] results in increased activity of CASP3 protein Dactinomycin results in increased activity of CASP3 protein Dactinomycin results in decreased expression of CASP3 mRNA |
CTD |
PMID:10663630 PMID:16001973 PMID:16492401 PMID:21496118 PMID:22654482 PMID:23300732 PMID:26670606 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp7 |
caspase 7 |
multiple interactions decreases expression |
ISO |
[Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP7 protein; [TNF co-treated with Dactinomycin] results in increased activity of CASP7 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP7 protein; Dactinomycin promotes the reaction [TNF results in increased activity of CASP7 protein] Dactinomycin results in decreased expression of CASP7 mRNA |
CTD |
PMID:16001973 PMID:16492401 PMID:17707539 PMID:21496118 |
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NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
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G |
Casp8 |
caspase 8 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of CASP8 mRNA |
CTD |
PMID:16001973 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage |
ISO |
[Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP9 protein Dactinomycin results in increased cleavage of CASP9 protein |
CTD |
PMID:17707539 PMID:26670606 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cav1 |
caveolin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [rosiglitazone results in increased expression of CAV1 mRNA] |
CTD |
PMID:15314095 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA] |
CTD |
PMID:15531761 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [AGT protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA] |
CTD |
PMID:15531761 PMID:16705055 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccn4 |
cellular communication network factor 4 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased expression of CCN4 mRNA] |
CTD |
PMID:19238344 |
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NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248
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G |
Ccna2 |
cyclin A2 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Homocysteine results in increased expression of CCNA2 mRNA] |
CTD |
PMID:8550827 |
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NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577
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G |
Ccnd1 |
cyclin D1 |
decreases stability |
ISO |
Dactinomycin results in decreased stability of CCND1 mRNA |
CTD |
PMID:15610522 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd1d1 |
CD1d1 molecule |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of CD1D mRNA] |
CTD |
PMID:17392484 |
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NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
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G |
Cd28 |
Cd28 molecule |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CD28 protein] |
CTD |
PMID:11465111 |
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NCBI chr 9:62,166,324...62,194,674
Ensembl chr 9:62,166,192...62,194,685
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions decreases expression |
ISO |
2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone inhibits the reaction [Dactinomycin results in increased expression of and affects the localization of CDKN1A protein]; Dactinomycin results in increased expression of and affects the localization of CDKN1A protein Dactinomycin results in decreased expression of CDKN1A protein |
CTD |
PMID:12807743 PMID:14601052 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
decreases expression |
ISO |
Dactinomycin results in decreased expression of CEBPB mRNA |
CTD |
PMID:16001973 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cel |
carboxyl ester lipase |
increases expression |
ISO |
Dactinomycin results in increased expression of CEL mRNA |
CTD |
PMID:21527772 |
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NCBI chr 3:11,883,532...11,891,035
Ensembl chr 3:11,883,532...11,891,035
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G |
Cflar |
CASP8 and FADD-like apoptosis regulator |
decreases expression |
ISO |
Dactinomycin results in decreased expression of CFLAR protein |
CTD |
PMID:11234897 PMID:14601052 |
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NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
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G |
Ckb |
creatine kinase B |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Estradiol results in increased expression of CKB protein]; Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of CKB protein] |
CTD |
PMID:7839363 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clmn |
calmin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of CLMN mRNA] |
CTD |
PMID:16688769 |
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NCBI chr 6:123,707,710...123,807,283
Ensembl chr 6:123,713,507...123,807,272
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G |
Cnmd |
chondromodulin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [hydroquinone results in increased expression of CNMD protein] |
CTD |
PMID:19525446 |
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NCBI chr15:55,041,548...55,066,297
Ensembl chr15:55,041,561...55,066,297
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [ results in increased expression of CNR1 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [ results in increased expression of CNR2 mRNA] |
CTD |
PMID:21525939 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA] Dactinomycin results in decreased expression of COL1A1 mRNA |
CTD |
PMID:11216681 PMID:18253093 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [LEP protein results in increased expression of COL1A2 mRNA] |
CTD |
PMID:12704794 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Crabp2 |
cellular retinoic acid binding protein 2 |
increases expression |
ISO |
Dactinomycin results in increased expression of CRABP2 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
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G |
Csf2 |
colony stimulating factor 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Reactive Oxygen Species results in increased expression of CSF2 protein] Dactinomycin inhibits the reaction [IL1B results in increased secretion of CSF2 protein]; Dactinomycin inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein] |
CTD |
PMID:9606035 PMID:10645887 PMID:11752025 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Ctf1 |
cardiotrophin 1 |
multiple interactions |
EXP |
Dactinomycin promotes the reaction [Spironolactone inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]]; Dactinomycin promotes the reaction [Valsartan inhibits the reaction [AGT protein results in increased expression of CTF1 mRNA]] |
CTD |
PMID:23288202 |
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NCBI chr 1:182,328,035...182,336,346
Ensembl chr 1:182,328,090...182,333,335
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of CYCS mRNA] |
CTD |
PMID:21281706 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Cygb |
cytoglobin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole results in increased expression of CYGB mRNA] |
CTD |
PMID:25781201 |
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NCBI chr10:101,877,675...101,887,442
Ensembl chr10:101,877,676...101,887,442
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [chromium trioxide results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Copper results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Lead results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [SB 203580 results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tetrandrine results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tetrandrine results in increased expression of CYP1A1 protein]; Dactinomycin promotes the reaction [benz(a)anthracene results in increased expression of CYP1A1 mRNA]; Dactinomycin promotes the reaction [Cycloheximide results in increased expression of CYP1A1 mRNA] Dactinomycin results in decreased expression of CYP1A1 mRNA Dactinomycin inhibits the reaction [afimoxifene results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [dihydrotanshinone I results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [harman results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Itraconazole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Skatole results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [Sunitinib results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [T-2 Toxin results in increased expression of CYP1A1 mRNA]; Dactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:1934297 PMID:10359656 PMID:11577022 PMID:11752201 PMID:16093525 PMID:17283379 PMID:17606337 PMID:19901195 PMID:20187624 PMID:20732341 PMID:21262253 PMID:21732638 PMID:23288144 PMID:26318284 PMID:26640276 PMID:31470059 More...
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [cryptotanshinone results in increased expression of CYP1A2 mRNA]; Dactinomycin inhibits the reaction [dihydrotanshinone I results in increased expression of CYP1A2 mRNA]; Dactinomycin inhibits the reaction [tanshinone results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:21262253 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp1b1 |
cytochrome P450, family 1, subfamily b, polypeptide 1 |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [NSC 674495 results in increased expression of CYP1B1 mRNA] Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of CYP1B1 protein] Dactinomycin results in decreased expression of CYP1B1 mRNA Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of CYP1B1 mRNA] |
CTD |
PMID:11577022 PMID:11752201 PMID:21867498 |
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NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
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G |
Cyp2b1 |
cytochrome P450, family 2, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP2B10 mRNA] |
CTD |
PMID:9007836 |
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NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
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G |
Cyp2f4 |
cytochrome P450, family 2, subfamily f, polypeptide 4 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Skatole results in increased expression of CYP2F1 mRNA] |
CTD |
PMID:20187624 |
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NCBI chr 1:82,416,108...82,429,897
Ensembl chr 1:82,416,130...82,429,896
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G |
Cyp2s1 |
cytochrome P450, family 2, subfamily s, polypeptide 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP2S1 mRNA] |
CTD |
PMID:17277313 |
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NCBI chr 1:81,309,948...81,325,303
Ensembl chr 1:81,310,451...81,325,303
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions |
EXP ISO |
Dactinomycin inhibits the reaction [Methylcholanthrene results in increased expression of CYP3A2 mRNA]; Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP3A2 mRNA]; Dactinomycin inhibits the reaction [pyridine results in increased expression of CYP3A2 mRNA] Dactinomycin inhibits the reaction [o,p'-DDT results in increased expression of CYP3A4 mRNA]; Dactinomycin inhibits the reaction [U 0126 results in increased expression of CYP3A4 mRNA] |
CTD |
PMID:11181506 PMID:15795092 PMID:24819614 |
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NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp3a23-3a1 |
cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Phenobarbital results in increased expression of CYP3A23-3A1 mRNA]; Dactinomycin inhibits the reaction [pyridine results in increased expression of CYP3A23-3A1 mRNA] |
CTD |
PMID:11181506 |
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NCBI chr12:9,256,159...9,285,020
Ensembl chr12:9,254,475...9,285,030
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G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [U 0126 results in increased expression of CYP3A5 mRNA] |
CTD |
PMID:24819614 |
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NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Ddah2 |
dimethylarginine dimethylaminohydrolase 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Nebivolol results in increased expression of DDAH2 mRNA] |
CTD |
PMID:17977009 |
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NCBI chr20:3,761,460...3,764,718
Ensembl chr20:3,761,465...3,764,511
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G |
Dio3 |
iodothyronine deiodinase 3 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased activity of DIO3 protein] |
CTD |
PMID:18420745 |
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NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660
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G |
Dpysl4 |
dihydropyrimidinase-like 4 |
increases expression |
ISO |
Dactinomycin results in increased expression of DPYSL4 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 1:193,883,039...193,898,916
Ensembl chr 1:193,883,106...193,898,914
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G |
Edn1 |
endothelin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [EDN1 protein results in increased expression of ADRB2 mRNA] |
CTD |
PMID:22483689 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Ednra |
endothelin receptor type A |
multiple interactions |
EXP |
[Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA mRNA; [Dimethyl Sulfoxide co-treated with Dactinomycin] results in decreased expression of EDNRA protein; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRA mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRA protein] |
CTD |
PMID:20561571 |
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NCBI chr19:30,233,540...30,303,727
Ensembl chr19:30,233,571...30,297,049
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G |
Ednrb |
endothelin receptor type B |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Cyclosporine results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Dimethyl Sulfoxide results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRB mRNA]; Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [Smoke analog results in increased expression of EDNRB protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA] |
CTD |
PMID:20561571 PMID:20716444 PMID:22207076 PMID:25772258 |
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NCBI chr15:80,640,839...80,672,115
Ensembl chr15:80,643,043...80,672,115
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G |
Efnb2 |
ephrin B2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of EFNB2 mRNA] |
CTD |
PMID:16688769 |
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NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391
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G |
Egf |
epidermal growth factor |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA] |
CTD |
PMID:12632255 |
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NCBI chr 2:218,219,408...218,302,370
Ensembl chr 2:218,219,415...218,302,064
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGFR protein]; Dactinomycin inhibits the reaction [Methoxychlor results in increased expression of EGFR protein] |
CTD |
PMID:8888411 |
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NCBI chr14:91,176,931...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Egr1 |
early growth response 1 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Estradiol results in increased expression of EGR1 mRNA] |
CTD |
PMID:1717835 |
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NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Elovl3 |
ELOVL fatty acid elongase 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Norepinephrine results in increased expression of ELOVL3 mRNA]; Dactinomycin inhibits the reaction [rosiglitazone results in increased expression of ELOVL3 mRNA] |
CTD |
PMID:17726147 |
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NCBI chr 1:244,997,287...245,001,115
Ensembl chr 1:244,997,287...245,001,115
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G |
Emp1 |
epithelial membrane protein 1 |
increases expression |
ISO |
Dactinomycin results in increased expression of EMP1 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 4:168,212,901...168,233,039
Ensembl chr 4:168,212,861...168,232,904
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G |
Emp3 |
epithelial membrane protein 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of EMP3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 1:96,388,651...96,391,946
Ensembl chr 1:96,388,652...96,391,988
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G |
Epas1 |
endothelial PAS domain protein 1 |
increases stability |
EXP |
Dactinomycin results in increased stability of EPAS1 protein |
CTD |
PMID:23545307 |
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NCBI chr 6:7,790,236...7,871,246
Ensembl chr 6:7,790,647...7,871,228
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G |
F3 |
coagulation factor III, tissue factor |
decreases expression multiple interactions |
ISO |
Dactinomycin results in decreased expression of F3 mRNA Dactinomycin inhibits the reaction [indoleacetic acid results in increased expression of F3 mRNA] |
CTD |
PMID:30324315 |
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NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668
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G |
Fadd |
Fas associated via death domain |
decreases expression |
ISO |
Dactinomycin results in decreased expression of FADD mRNA |
CTD |
PMID:16001973 |
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NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
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G |
Fads3 |
fatty acid desaturase 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of FADS3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 1:206,685,667...206,702,538
Ensembl chr 1:206,685,894...206,704,769
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G |
Fbl |
fibrillarin |
affects localization |
ISO |
Dactinomycin analog affects the localization of FBL protein |
CTD |
PMID:10942594 |
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NCBI chr 1:83,469,832...83,478,932
Ensembl chr 1:83,469,832...83,478,932
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G |
Fcar |
Fc alpha receptor |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of FCAR mRNA] |
CTD |
PMID:21911031 |
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NCBI chr 1:69,626,458...69,660,558
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G |
Fgf2 |
fibroblast growth factor 2 |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [Sodium Chloride results in increased expression of FGF2 mRNA] Dactinomycin inhibits the reaction [FGF2 protein results in increased expression of SNCA protein] Dactinomycin results in decreased expression of FGF2 mRNA |
CTD |
PMID:12562524 PMID:26800359 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgfr1 |
Fibroblast growth factor receptor 1 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Triiodothyronine results in increased expression of FGFR1 mRNA] |
CTD |
PMID:12805413 |
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NCBI chr16:66,492,445...66,546,731
Ensembl chr16:66,494,042...66,547,350
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G |
Fhl1 |
four and a half LIM domains 1 |
multiple interactions |
EXP |
Dactinomycin promotes the reaction [25-hydroxycholesterol results in increased expression of FHL1 mRNA] |
CTD |
PMID:17161435 |
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NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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G |
Flnc |
filamin C |
increases expression |
ISO |
Dactinomycin results in increased expression of FLNC mRNA |
CTD |
PMID:21527772 |
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NCBI chr 4:58,034,088...58,061,882
Ensembl chr 4:58,034,189...58,061,844
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G |
Fn1 |
fibronectin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of FN1 mRNA] |
CTD |
PMID:18253093 |
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of FOS mRNA] Dactinomycin inhibits the reaction [Hemin results in increased expression of FOS mRNA] Dactinomycin results in decreased expression of FOS mRNA Dactinomycin inhibits the reaction [[Cycloheximide co-treated with Cadmium] results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [[EGF protein co-treated with Estradiol] results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Fructose results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of FOS mRNA]; Dactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA] |
CTD |
PMID:1696944 PMID:7564102 PMID:10381381 PMID:11123204 PMID:11353138 PMID:11568973 PMID:12632255 More...
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Fosl1 |
FOS like 1, AP-1 transcription factor subunit |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [Particulate Matter results in increased expression of FOSL1 mRNA]; Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of FOSL1 mRNA] Dactinomycin results in decreased expression of FOSL1 mRNA |
CTD |
PMID:14565943 |
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NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
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G |
G6pd |
glucose-6-phosphate dehydrogenase |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Isoproterenol results in increased activity of G6PD protein] |
CTD |
PMID:1978808 |
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NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [arsenite results in increased expression of GADD45A mRNA] Dactinomycin results in increased expression of GADD45A mRNA |
CTD |
PMID:17616671 PMID:21527772 |
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NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Galm |
galactose mutarotase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of GALM mRNA] |
CTD |
PMID:18052213 |
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NCBI chr 6:14,837,540...14,889,484
Ensembl chr 6:14,837,548...14,889,310
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G |
Gapdh |
glyceraldehyde-3-phosphate dehydrogenase |
increases expression |
ISO |
Dactinomycin results in increased expression of GAPDH mRNA |
CTD |
PMID:16001973 |
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NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235
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G |
Gas6 |
growth arrest specific 6 |
multiple interactions increases degradation |
ISO |
Phosphates promotes the reaction [Dactinomycin results in increased degradation of GAS6 mRNA] |
CTD |
PMID:20048160 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [Vitamin K 3 results in increased expression of GCLC mRNA] Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of GCLC protein] |
CTD |
PMID:11972604 PMID:24437944 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gdf15 |
growth differentiation factor 15 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [resveratrol results in increased expression of GDF15 mRNA] |
CTD |
PMID:17257620 |
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NCBI chr16:18,805,312...18,807,893
Ensembl chr16:18,805,239...18,808,055
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G |
Gdnf |
glial cell derived neurotrophic factor |
multiple interactions decreases expression |
EXP |
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of GDNF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of GDNF mRNA] Dactinomycin results in decreased expression of GDNF mRNA |
CTD |
PMID:22982731 |
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NCBI chr 2:56,893,992...56,919,935
Ensembl chr 2:56,895,010...56,917,209
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G |
Gfer |
growth factor, augmenter of liver regeneration |
increases secretion multiple interactions |
EXP |
Dactinomycin results in increased secretion of GFER protein Dactinomycin promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of GFER protein]; lipopolysaccharide, Escherichia coli O111 B4 promotes the reaction [Dactinomycin results in increased secretion of GFER protein] |
CTD |
PMID:23073658 |
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NCBI chr10:13,718,489...13,721,782
Ensembl chr10:13,718,489...13,720,869
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G |
Gpr137b |
G protein-coupled receptor 137B |
increases expression |
ISO |
Dactinomycin results in increased expression of GPR137B mRNA |
CTD |
PMID:21527772 |
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NCBI chr17:86,003,630...86,041,841
Ensembl chr17:85,966,921...86,041,835
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] |
CTD |
PMID:29479035 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Grm5 |
glutamate metabotropic receptor 5 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 mRNA]; Dactinomycin inhibits the reaction [Dextroamphetamine results in increased expression of GRM5 protein] |
CTD |
PMID:11665859 |
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NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of GSTA1 mRNA] |
CTD |
PMID:28483492 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Gsta5 |
glutathione S-transferase alpha 5 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Lead results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of GSTA1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GSTA1 mRNA] |
CTD |
PMID:16243960 |
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NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472
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G |
Gstp1 |
glutathione S-transferase pi 1 |
decreases response to substance |
EXP |
GSTP1 protein results in decreased susceptibility to Dactinomycin |
CTD |
PMID:11455017 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
H2ax |
H2A.X variant histone |
increases expression |
ISO |
Dactinomycin results in increased expression of H2AX protein |
CTD |
PMID:31226288 |
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NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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G |
Hbegf |
heparin-binding EGF-like growth factor |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [Sodium Chloride results in increased expression of HBEGF mRNA] Dactinomycin results in decreased expression of HBEGF mRNA |
CTD |
PMID:26800359 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hgf |
hepatocyte growth factor |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Berberine results in increased expression of HGF protein] |
CTD |
PMID:29408570 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of HIF1A protein] |
CTD |
PMID:12479793 PMID:19958256 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [Ammonium Chloride results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [ginsenoside Rb1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Lipid Peroxides results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Nitroprusside results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Oxygen results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Plant Extracts results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Potassium Dichromate results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Resveratrol results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Ritonavir results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [tricarbonyldichlororuthenium (II) dimer results in increased expression of HMOX1 protein]; Dactinomycin results in decreased susceptibility to [surfactin peptide results in increased expression of HMOX1 mRNA]; HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]] Dactinomycin results in decreased expression of HMOX1 protein Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [cobaltous chloride results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [resveratrol results in increased expression of HMOX1 mRNA] Dactinomycin inhibits the reaction [fisetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 mRNA]; Dactinomycin inhibits the reaction [puerarin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of HMOX1 protein]; Dactinomycin inhibits the reaction [Triterpenes analog results in increased expression of HMOX1 protein] |
CTD |
PMID:8764571 PMID:9747510 PMID:9808084 PMID:11880364 PMID:12763371 PMID:15118350 PMID:15582353 PMID:15588712 PMID:15876423 PMID:15965080 PMID:16647178 PMID:17002867 PMID:18332044 PMID:18357586 PMID:19781563 PMID:20060010 PMID:20833156 PMID:21840424 PMID:24437944 PMID:25239868 PMID:26283888 PMID:26385185 PMID:26968795 PMID:27867098 PMID:30076913 More...
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa1 |
heterogeneous nuclear ribonucleoprotein A1 |
multiple interactions affects localization |
ISO |
Dactinomycin affects the reaction [HNRNPA1 protein binds to CYP2A5 mRNA] Dactinomycin affects the localization of HNRNPA1 protein |
CTD |
PMID:12754101 |
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NCBI chr 7:134,375,318...134,381,610
Ensembl chr 7:134,375,150...134,381,609
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G |
Homer3 |
homer scaffold protein 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of HOMER3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr16:19,132,177...19,142,739
Ensembl chr16:19,132,162...19,142,680
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G |
Hras |
HRas proto-oncogene, GTPase |
multiple interactions |
ISO |
Dactinomycin promotes the reaction [[Zinostatin co-treated with Glutathione] results in increased cleavage of HRAS gene] |
CTD |
PMID:9345283 |
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NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615
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G |
Hsd11b2 |
hydroxysteroid 11-beta dehydrogenase 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Bexarotene results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [tributyltin results in increased expression of HSD11B2 mRNA]; Dactinomycin inhibits the reaction [triphenyltin chloride results in increased expression of HSD11B2 mRNA] |
CTD |
PMID:31927052 |
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NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899
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G |
Hsf1 |
heat shock transcription factor 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of HSF1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of HSF1 protein] |
CTD |
PMID:30309986 |
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NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dithiothreitol results in increased expression of HSP90B1 mRNA] |
CTD |
PMID:34244458 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
multiple interactions decreases expression |
EXP ISO |
Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [lead acetate results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Mercuric Chloride results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 mRNA]; Dactinomycin inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein] Dactinomycin results in decreased expression of HSPA5 mRNA [Arsenic Trioxide co-treated with Dactinomycin] results in decreased expression of HSPA5 mRNA; [Arsenic Trioxide co-treated with Dactinomycin] results in increased expression of HSPA5 protein |
CTD |
PMID:17915553 PMID:34560123 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Htr3a |
5-hydroxytryptamine receptor 3A |
multiple interactions |
ISO |
Dactinomycin promotes the reaction [Dronabinol results in decreased activity of HTR3A protein] |
CTD |
PMID:20800662 |
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NCBI chr 8:49,242,018...49,254,475
Ensembl chr 8:49,242,020...49,254,389
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G |
Id1 |
inhibitor of DNA binding 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of ID1 mRNA] |
CTD |
PMID:16494909 |
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NCBI chr 3:141,210,666...141,212,420
Ensembl chr 3:141,211,267...141,212,419
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G |
Ier3 |
immediate early response 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [afimoxifene results in increased expression of IER3 mRNA] |
CTD |
PMID:16849584 |
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NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583
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G |
Ier5 |
immediate early response 5 |
increases expression |
ISO |
Dactinomycin results in increased expression of IER5 mRNA |
CTD |
PMID:21527772 |
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NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227
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G |
Ifna1 |
interferon, alpha 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IFNA1 protein results in increased expression of TYMP mRNA] |
CTD |
PMID:15937643 |
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NCBI chr 5:103,095,767...103,098,260
Ensembl chr 5:103,097,356...103,097,925
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G |
Ifnb1 |
interferon beta 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IFNB1 protein results in increased expression of TYMP mRNA] |
CTD |
PMID:15937643 |
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NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523
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G |
Ifng |
interferon gamma |
multiple interactions |
ISO |
[Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IFNG mRNA; Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA]; Dactinomycin inhibits the reaction [IFNG protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [Tretinoin promotes the reaction [IFNG protein results in increased expression of IRF1 protein]] |
CTD |
PMID:15937643 PMID:16085646 PMID:26278786 PMID:29594315 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf1 |
insulin-like growth factor 1 |
decreases response to substance |
ISO |
IGF1 protein results in decreased susceptibility to Dactinomycin |
CTD |
PMID:9525472 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Il10 |
interleukin 10 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Zymosan results in increased expression of IL10 mRNA] |
CTD |
PMID:17458858 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il11 |
interleukin 11 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Formaldehyde results in increased expression of IL11 mRNA] |
CTD |
PMID:22138297 |
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NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
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G |
Il17a |
interleukin 17A |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Glucose results in increased secretion of IL17A protein] |
CTD |
PMID:18310510 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [IL1A protein results in increased expression of FOS mRNA] |
CTD |
PMID:7564102 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [IL1B protein results in increased abundance of Dinoprostone]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of TGFB1 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased secretion of TGFB1 protein]; Dactinomycin inhibits the reaction [IL1B results in increased abundance of Dinoprostone]; Dactinomycin inhibits the reaction [IL1B results in increased abundance of Nitric Oxide]; Dactinomycin inhibits the reaction [IL1B results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [IL1B results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [IL1B results in increased secretion of CSF2 protein] Dactinomycin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA] Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA alternative form]; Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA] |
CTD |
PMID:9606035 PMID:11286988 PMID:12512699 PMID:16338976 PMID:16365456 PMID:16492401 PMID:17641275 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il2 |
interleukin 2 |
multiple interactions |
ISO |
[Dactinomycin co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of IL2 mRNA |
CTD |
PMID:29594315 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il27ra |
interleukin 27 receptor subunit alpha |
increases expression |
ISO |
Dactinomycin results in increased expression of IL27RA mRNA |
CTD |
PMID:21527772 |
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NCBI chr19:24,109,698...24,121,977
Ensembl chr19:24,109,972...24,121,938
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G |
Il6 |
interleukin 6 |
decreases secretion |
ISO |
Dactinomycin results in decreased secretion of IL6 protein |
CTD |
PMID:11216681 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased expression of SLC27A1 mRNA] |
CTD |
PMID:10777552 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Irf1 |
interferon regulatory factor 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin promotes the reaction [IFNG protein results in increased expression of IRF1 protein]]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of IRF1 mRNA] |
CTD |
PMID:16085646 PMID:16636311 |
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NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
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G |
Itga2b |
integrin subunit alpha 2b |
increases expression |
ISO |
Dactinomycin results in increased expression of ITGA2B mRNA |
CTD |
PMID:21527772 |
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NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168
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G |
Itpr1 |
inositol 1,4,5-trisphosphate receptor, type 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Ethanol results in increased expression of ITPR1 mRNA]; Dactinomycin inhibits the reaction [linsidomine results in increased expression of ITPR1 mRNA] |
CTD |
PMID:17241155 |
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NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Aldosterone results in increased phosphorylation of JAK2 protein] |
CTD |
PMID:15932931 |
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NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [beryllium sulfate results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA] Dactinomycin results in decreased expression of JUN mRNA Dactinomycin inhibits the reaction [Cadmium results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Fructose results in increased expression of JUN mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of JUN mRNA] |
CTD |
PMID:1696944 PMID:11123204 PMID:11353138 PMID:11568973 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Kif1a |
kinesin family member 1A |
increases expression |
ISO |
Dactinomycin results in increased expression of KIF1A mRNA |
CTD |
PMID:21527772 |
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NCBI chr 9:93,563,033...93,647,412
Ensembl chr 9:93,563,045...93,647,480
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [[KRAS protein mutant form affects the susceptibility to vemurafenib] which results in increased expression of TNFRSF10B mRNA] |
CTD |
PMID:27222248 |
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NCBI chr 4:178,185,418...178,218,484
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G |
Krt80 |
keratin 80 |
increases expression |
ISO |
Dactinomycin results in increased expression of KRT80 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 7:132,464,807...132,485,026
Ensembl chr 7:132,463,218...132,485,508
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G |
Lamc2 |
laminin subunit gamma 2 |
increases expression |
ISO |
Dactinomycin results in increased expression of LAMC2 mRNA |
CTD |
PMID:21527772 |
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NCBI chr13:65,284,664...65,344,200
Ensembl chr13:65,284,664...65,344,200
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions decreases expression |
ISO |
Ascorbic Acid inhibits the reaction [Dactinomycin results in decreased expression of LDLR mRNA] |
CTD |
PMID:32913121 |
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NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [LEP protein results in increased expression of COL1A2 mRNA] |
CTD |
PMID:12704794 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lgals3 |
galectin 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of LGALS3 protein] |
CTD |
PMID:21821001 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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G |
Lgals7 |
galectin 7 |
increases expression |
ISO |
Dactinomycin results in increased expression of LGALS7 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 1:84,148,612...84,152,016
Ensembl chr 1:84,150,252...84,152,015
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G |
Lmnb1 |
lamin B1 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of LMNB1 mRNA |
CTD |
PMID:16001973 |
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NCBI chr18:50,175,861...50,215,210
Ensembl chr18:50,175,874...50,214,502
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Ethanol results in increased expression of MAP1LC3B protein] |
CTD |
PMID:24095927 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of MAP2K4 mRNA |
CTD |
PMID:16001973 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of MAP3K7 mRNA |
CTD |
PMID:16001973 |
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NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases expression |
ISO EXP |
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] Dactinomycin results in increased expression of MAPK1 protein |
CTD |
PMID:14640974 PMID:15959627 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases expression |
ISO EXP |
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] Dactinomycin results in increased expression of MAPK3 protein PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:14640974 PMID:15959627 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mcl1 |
MCL1 apoptosis regulator, BCL2 family member |
decreases expression multiple interactions |
ISO |
Dactinomycin results in decreased expression of MCL1 mRNA Dactinomycin inhibits the reaction [IL1B results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of MCL1 protein]; Quercetin promotes the reaction [Dactinomycin results in decreased expression of MCL1 mRNA] |
CTD |
PMID:16492401 PMID:21750559 |
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NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
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G |
Mir21 |
microRNA 21 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dehydroepiandrosterone results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [Dihydrotestosterone results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [Estradiol results in decreased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [fludioxonil results in increased expression of MIR21 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of MIR21 mRNA] |
CTD |
PMID:19264808 PMID:23052036 PMID:25969534 |
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NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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G |
Mir22 |
microRNA 22 |
multiple interactions |
ISO |
[Dactinomycin co-treated with Dehydroepiandrosterone] results in increased expression of MIR22 mRNA; Dactinomycin promotes the reaction [Dehydroepiandrosterone results in increased expression of MIR22 mRNA] |
CTD |
PMID:25969534 |
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NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
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G |
Mllt11 |
MLLT11, transcription factor 7 cofactor |
increases expression |
ISO |
Dactinomycin results in increased expression of MLLT11 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 2:182,795,790...182,804,960
Ensembl chr 2:182,795,790...182,797,199
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G |
Mmp1 |
matrix metallopeptidase 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of MMP1 protein] |
CTD |
PMID:19136476 |
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NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [arsenic trioxide results in increased expression of MMP9 mRNA] Dactinomycin results in decreased expression of MMP9 mRNA |
CTD |
PMID:24956101 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mn1 |
MN1 proto-oncogene, transcriptional regulator |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Calcitriol results in increased expression of MN1 mRNA] |
CTD |
PMID:15890672 |
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NCBI chr12:45,184,060...45,220,102
Ensembl chr12:45,183,085...45,221,651
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G |
Mrpl41 |
mitochondrial ribosomal protein L41 |
multiple interactions |
ISO |
Dactinomycin promotes the reaction [MRPL41 protein results in increased stability of and affects the localization of TP53 protein] |
CTD |
PMID:16024796 |
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NCBI chr 3:7,780,658...7,781,576
Ensembl chr 3:7,779,143...7,782,818
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [zinc chloride results in increased expression of MT2A mRNA] |
CTD |
PMID:17234632 |
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NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [pirinixic acid results in increased expression of MTTP mRNA] |
CTD |
PMID:15537571 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
decreases expression multiple interactions |
ISO EXP |
Dactinomycin results in decreased expression of MYC mRNA Dactinomycin inhibits the reaction [Cadmium results in increased expression of MYC mRNA] Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of MYC mRNA] |
CTD |
PMID:1696944 PMID:11353138 PMID:16001973 PMID:21527772 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Mylk |
myosin light chain kinase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK protein] |
CTD |
PMID:15701621 |
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NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Nav2 |
neuron navigator 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of NAV2 mRNA] |
CTD |
PMID:16688769 |
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NCBI chr 1:98,957,629...99,322,339
Ensembl chr 1:98,663,759...99,322,337
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G |
Ncf1 |
neutrophil cytosolic factor 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Benzo(a)pyrene results in increased expression of NCF1 mRNA] |
CTD |
PMID:19559082 |
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NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646
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G |
Ndrg1 |
N-myc downstream regulated 1 |
multiple interactions |
ISO |
[nickel chloride co-treated with Dactinomycin] results in increased stability of NDRG1 mRNA; [Oxygen deficiency co-treated with Dactinomycin] results in increased stability of NDRG1 mRNA |
CTD |
PMID:10646848 |
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NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
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G |
Nedd9 |
neural precursor cell expressed, developmentally down-regulated 9 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tretinoin results in increased expression of NEDD9 mRNA] |
CTD |
PMID:16688769 |
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NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019
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G |
Neto2 |
neuropilin and tolloid like 2 |
increases expression |
ISO |
Dactinomycin results in increased expression of NETO2 mRNA |
CTD |
PMID:21527772 |
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NCBI chr19:21,344,299...21,418,182
Ensembl chr19:21,344,289...21,417,023
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of NFE2L2 mRNA] |
CTD |
PMID:22019695 PMID:24632381 |
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NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
decreases expression multiple interactions |
ISO |
Dactinomycin results in decreased expression of NFKB1 mRNA [RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 PMID:16001973 |
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NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nfkbia |
NFKB inhibitor alpha |
multiple interactions |
ISO |
NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]] |
CTD |
PMID:11880364 |
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NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Ngf |
nerve growth factor |
multiple interactions decreases expression |
EXP |
Dactinomycin inhibits the reaction [9-deoxy-9,10-didehydro-12,13-didehydro-13,14-dihydroprostaglandin D2 analog results in increased expression of NGF mRNA]; Dactinomycin inhibits the reaction [NEPP11 compound results in increased expression of NGF mRNA] Dactinomycin results in decreased expression of NGF mRNA |
CTD |
PMID:22982731 |
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NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452
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G |
Nlrp3 |
NLR family, pyrin domain containing 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Asbestos, Crocidolite results in increased expression of NLRP3 mRNA] |
CTD |
PMID:23937860 |
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NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [IL1B protein results in increased expression of NOS2 mRNA] |
CTD |
PMID:11286988 |
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nppc |
natriuretic peptide C |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Estradiol results in increased expression of NPPC mRNA] |
CTD |
PMID:9435603 |
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NCBI chr 9:87,320,051...87,324,251
Ensembl chr 9:87,320,051...87,324,251
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [Biological Products results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Itraconazole results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Ketoconazole results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Lead results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Dactinomycin promotes the reaction [Chromium inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]] Dactinomycin inhibits the reaction [notoginsenoside R1 results in increased expression of NQO1 protein] |
CTD |
PMID:16243960 PMID:17923278 PMID:18474416 PMID:22570534 PMID:24437944 |
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NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr0b1 |
nuclear receptor subfamily 0, group B, member 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of NR0B1 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of NR0B1 mRNA] |
CTD |
PMID:18787026 |
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NCBI chr X:50,756,886...50,761,014
Ensembl chr X:50,756,886...50,761,011
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Fenofibrate results in increased expression of NR0B2 mRNA] |
CTD |
PMID:19593819 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] |
CTD |
PMID:25257666 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
multiple interactions |
EXP ISO |
Dactinomycin inhibits the reaction [Clofibrate results in increased expression of NR1I2 protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of NR1I2 mRNA]; Dactinomycin inhibits the reaction [perfluorodecanoic acid results in increased expression of NR1I2 protein] Dactinomycin inhibits the reaction [ochratoxin A results in decreased expression of NR1I2 mRNA] |
CTD |
PMID:15826607 PMID:20599767 PMID:26341324 |
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NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
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G |
Nr3c1 |
nuclear receptor subfamily 3, group C, member 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dexamethasone affects the localization of NR3C1 protein]; Dactinomycin inhibits the reaction [Dexamethasone binds to NR3C1 protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased degradation of NR3C1 protein] |
CTD |
PMID:21569845 |
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NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
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G |
Nthl1 |
nth-like DNA glycosylase 1 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of NTHL1 mRNA |
CTD |
PMID:21527772 |
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NCBI chr10:13,655,791...13,661,958
Ensembl chr10:13,655,785...13,661,957
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G |
Opa1 |
OPA1, mitochondrial dynamin like GTPase |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form] |
CTD |
PMID:20678484 |
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NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109
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G |
Pappa |
pappalysin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PAPPA mRNA] |
CTD |
PMID:16338976 |
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NCBI chr 5:78,497,660...78,735,873
Ensembl chr 5:78,498,300...78,730,666
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
multiple interactions |
ISO |
[TNF co-treated with Dactinomycin] results in increased cleavage of PARP1 protein; Dactinomycin promotes the reaction [TNF results in increased cleavage of PARP1 protein]; PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein] PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein] |
CTD |
PMID:14640974 PMID:16492401 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pcna |
proliferating cell nuclear antigen |
decreases expression multiple interactions |
EXP ISO |
Dactinomycin results in decreased expression of PCNA protein Dactinomycin inhibits the reaction [Vitamin K 3 results in decreased expression of PCNA protein] |
CTD |
PMID:15959627 PMID:21533478 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Plat |
plasminogen activator, tissue type |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAT mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAT mRNA]; Dactinomycin inhibits the reaction [Resveratrol results in increased expression of PLAT mRNA] |
CTD |
PMID:11236827 |
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NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions increases expression |
ISO |
Dactinomycin inhibits the reaction [Catechin results in increased expression of PLAU mRNA]; Dactinomycin inhibits the reaction [Quercetin results in increased expression of PLAU mRNA]; Dactinomycin inhibits the reaction [resveratrol results in increased expression of PLAU mRNA] Dactinomycin results in increased expression of PLAU mRNA |
CTD |
PMID:11236827 PMID:21527772 |
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NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]; PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
CTD |
PMID:14640974 |
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NCBI chr 2:110,849,205...111,047,692
Ensembl chr 2:110,893,608...111,047,692
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G |
Pld2 |
phospholipase D2 |
multiple interactions |
ISO |
PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein]; PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of AKT1 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein]; PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
CTD |
PMID:14640974 |
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NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808
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G |
Polh |
DNA polymerase eta |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [fotemustine results in increased expression of POLH mRNA] |
CTD |
PMID:25125662 |
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NCBI chr 9:14,778,355...14,813,210
Ensembl chr 9:14,777,888...14,812,723
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G |
Polr2a |
RNA polymerase II subunit A |
decreases phosphorylation increases phosphorylation multiple interactions |
ISO |
Dactinomycin results in decreased phosphorylation of POLR2A protein Dactinomycin results in increased phosphorylation of POLR2A protein [Dactinomycin co-treated with sodium arsenite] results in increased phosphorylation of POLR2A protein |
CTD |
PMID:8126066 |
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NCBI chr10:54,452,438...54,478,486
Ensembl chr10:54,452,441...54,478,455
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G |
Pomt1 |
protein-O-mannosyltransferase 1 |
increases expression |
ISO |
Dactinomycin results in increased expression of POMT1 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 3:15,520,717...15,538,579
Ensembl chr 3:15,520,481...15,538,581
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G |
Prdx1 |
peroxiredoxin 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [sodium arsenate results in increased expression of PRDX1 mRNA]; Dactinomycin inhibits the reaction [sodium arsenate results in increased expression of PRDX1 protein] |
CTD |
PMID:11796722 |
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NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
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G |
Prdx6 |
peroxiredoxin 6 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Hydrogen Peroxide results in increased expression of PRDX6 mRNA]; Dactinomycin inhibits the reaction [Paraquat results in increased expression of PRDX6 mRNA] |
CTD |
PMID:12851211 |
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NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
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G |
Prkcd |
protein kinase C, delta |
multiple interactions |
ISO |
PLD1 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein] PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PRKCD protein] |
CTD |
PMID:14640974 |
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NCBI chr16:5,769,226...5,807,214
Ensembl chr16:5,769,215...5,799,352
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G |
Prl |
prolactin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [PRL protein results in increased expression of SLC30A2 mRNA] |
CTD |
PMID:19494234 |
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NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062
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G |
Procr |
protein C receptor |
increases expression |
ISO |
Dactinomycin results in increased expression of PROCR mRNA |
CTD |
PMID:21527772 |
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NCBI chr 3:144,254,596...144,258,863
Ensembl chr 3:144,254,380...144,258,903
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G |
Prom1 |
prominin 1 |
decreases expression multiple interactions |
ISO |
Dactinomycin results in decreased expression of PROM1 mRNA Dactinomycin results in decreased expression of and affects the localization of PROM1 protein |
CTD |
PMID:31226288 |
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NCBI chr14:66,989,545...67,094,534
Ensembl chr14:66,990,160...67,094,527
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions decreases expression |
ISO EXP |
Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Sodium Fluoride results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [Zinc results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Zinc results in increased expression of PTGS2 protein] Dactinomycin inhibits the reaction [nickel chloride results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [nickel sulfide results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA] Dactinomycin results in decreased expression of PTGS2 mRNA Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 mRNA]; Dactinomycin inhibits the reaction [Corticosterone results in increased expression of PTGS2 protein]; Dactinomycin inhibits the reaction [IL1B protein results in increased expression of PTGS2 mRNA] |
CTD |
PMID:9576062 PMID:11286988 PMID:16894348 PMID:17065197 PMID:18513776 PMID:18650268 PMID:19376214 PMID:24967690 More...
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NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
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G |
Ptk2 |
protein tyrosine kinase 2 |
decreases expression |
EXP |
Dactinomycin results in decreased expression of PTK2 protein |
CTD |
PMID:15959627 |
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NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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G |
Rad51 |
RAD51 recombinase |
multiple interactions decreases expression |
ISO |
tetrachlorobenzoquinone promotes the reaction [Dactinomycin results in decreased expression of RAD51 mRNA] |
CTD |
PMID:27989139 |
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NCBI chr 3:106,099,753...106,125,038
Ensembl chr 3:106,100,381...106,125,035
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G |
Raf1 |
Raf-1 proto-oncogene, serine/threonine kinase |
decreases expression |
EXP |
Dactinomycin results in decreased expression of RAF1 protein |
CTD |
PMID:15959627 |
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NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317
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G |
Rel |
REL proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
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NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
ISO |
[RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; RELA protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Ren |
renin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dobutamine results in increased secretion of REN protein]; Dactinomycin inhibits the reaction [Terbutaline results in increased secretion of REN protein] |
CTD |
PMID:9203624 |
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NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489
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G |
Retsat |
retinol saturase |
increases expression |
ISO |
Dactinomycin results in increased expression of RETSAT mRNA |
CTD |
PMID:21527772 |
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NCBI chr 4:104,653,306...104,662,069
Ensembl chr 4:104,653,155...104,668,310
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G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB mRNA]; Dactinomycin inhibits the reaction [cytotoxic necrotizing factor type 1 results in increased expression of RHOB protein] |
CTD |
PMID:23732113 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Ripply3 |
ripply transcriptional repressor 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of RIPPLY3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr11:33,648,471...33,656,587
Ensembl chr11:33,648,486...33,656,584
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G |
Rnf213 |
ring finger protein 213 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA] |
CTD |
PMID:26278786 |
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NCBI chr10:104,656,329...104,755,669
Ensembl chr10:104,656,883...104,757,918
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G |
Ros1 |
ROS proto-oncogene 1 , receptor tyrosine kinase |
increases expression |
ISO |
Dactinomycin results in increased expression of ROS1 mRNA |
CTD |
PMID:16001973 |
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NCBI chr20:31,432,636...31,583,998
Ensembl chr20:31,432,637...31,583,865
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G |
Rpl34 |
ribosomal protein L34 |
increases expression |
ISO |
Dactinomycin results in increased expression of RPL34 mRNA |
CTD |
PMID:21527772 |
|
NCBI chr 2:219,284,373...219,288,108
Ensembl chr 2:219,284,382...219,288,111
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
multiple interactions |
ISO |
PLD1 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] PLD2 protein promotes the reaction [Dactinomycin results in increased phosphorylation of and results in increased activity of RPS6KB1 protein] |
CTD |
PMID:14640974 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Rras |
RAS related |
increases expression |
ISO |
Dactinomycin results in increased expression of RRAS mRNA |
CTD |
PMID:21527772 |
|
NCBI chr 1:95,500,582...95,504,362
Ensembl chr 1:95,500,566...95,504,357
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G |
Sat1 |
spermidine/spermine N1-acetyl transferase 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [N(1),N(11)-diethylnorspermine results in increased expression of SAT1 mRNA] |
CTD |
PMID:16637064 |
|
NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [ciprofibrate results in increased expression of SCD1 mRNA] |
CTD |
PMID:11172741 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scnn1b |
sodium channel epithelial 1 subunit beta |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of SCNN1B mRNA] |
CTD |
PMID:10942727 |
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NCBI chr 1:176,430,063...176,484,451
Ensembl chr 1:176,430,103...176,484,451
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G |
Scnn1g |
sodium channel epithelial 1 subunit gamma |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of SCNN1G mRNA] |
CTD |
PMID:10942727 |
|
NCBI chr 1:176,304,942...176,338,816
Ensembl chr 1:176,304,942...176,338,816
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G |
Sdc3 |
syndecan 3 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Estradiol results in increased expression of SDC3 mRNA] |
CTD |
PMID:11024013 |
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NCBI chr 5:142,965,659...142,998,390
Ensembl chr 5:142,965,591...142,996,480
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G |
Sesn2 |
sestrin 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [erastin results in increased expression of SESN2 mRNA] |
CTD |
PMID:31323261 |
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NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260
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G |
Sfn |
stratifin |
increases expression |
ISO |
Dactinomycin results in increased expression of SFN mRNA |
CTD |
PMID:21527772 |
|
Ensembl chr 5:145,826,201...145,831,314
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G |
Sgk1 |
serum/glucocorticoid regulated kinase 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 mRNA]; Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of SGK1 protein] |
CTD |
PMID:25128767 |
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NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
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G |
Shh |
sonic hedgehog signaling molecule |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [SHH protein alternative form results in increased expression of ABCG2 protein] |
CTD |
PMID:21625222 |
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NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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G |
Sirt1 |
sirtuin 1 |
multiple interactions |
ISO |
Dactinomycin affects the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA] TAF15 mRNA inhibits the reaction [Dactinomycin results in decreased expression of SIRT1 mRNA] |
CTD |
PMID:30055241 PMID:35307376 |
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NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
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G |
Slc25a14 |
solute carrier family 25 member 14 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SLC25A14 mRNA]; Dactinomycin inhibits the reaction [Dopamine results in increased expression of SLC25A14 mRNA] |
CTD |
PMID:20600837 |
|
NCBI chr X:127,807,630...127,845,823
Ensembl chr X:127,807,449...127,845,823
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G |
Slc27a1 |
solute carrier family 27 member 1 |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [[[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased expression of SLC27A1 mRNA] Dactinomycin inhibits the reaction [alitretinoin results in increased expression of SLC27A1 mRNA] |
CTD |
PMID:10777552 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Slc2a2 |
solute carrier family 2 member 2 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A2 mRNA]; Dactinomycin inhibits the reaction [Glucose results in increased expression of SLC2A2 mRNA] |
CTD |
PMID:12787936 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc2a5 |
solute carrier family 2 member 5 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Fructose promotes the reaction [SLC2A5 protein results in increased uptake of Fructose]]; Dactinomycin inhibits the reaction [Fructose results in increased expression of SLC2A5 mRNA] |
CTD |
PMID:11123204 |
|
NCBI chr 5:160,583,055...160,609,994
Ensembl chr 5:160,583,234...160,611,106
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G |
Slc30a2 |
solute carrier family 30 member 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [PRL protein results in increased expression of SLC30A2 mRNA] |
CTD |
PMID:19494234 |
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NCBI chr 5:146,559,733...146,571,957
Ensembl chr 5:146,559,733...146,571,956
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G |
Slc30a5 |
solute carrier family 30 member 5 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [zinc chloride results in decreased expression of SLC30A5 mRNA] |
CTD |
PMID:17234632 |
|
NCBI chr 2:31,945,745...31,975,969
Ensembl chr 2:31,945,729...31,975,934
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G |
Slc39a10 |
solute carrier family 39 member 10 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in increased expression of SLC39A10 mRNA] |
CTD |
PMID:21738690 |
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NCBI chr 9:54,836,841...54,960,325
Ensembl chr 9:54,876,141...54,960,325
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G |
Slc39a4 |
solute carrier family 39 member 4 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Zinc deficiency results in increased expression of SLC39A4 mRNA]; Dactinomycin inhibits the reaction [Zinc results in decreased expression of SLC39A4 mRNA] |
CTD |
PMID:18020946 |
|
NCBI chr 7:108,333,380...108,337,553
Ensembl chr 7:108,333,381...108,337,553
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G |
Slc3a2 |
solute carrier family 3 member 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of SLC3A2 mRNA] |
CTD |
PMID:26621329 |
|
NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
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G |
Slc40a1 |
solute carrier family 40 member 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Cadmium results in increased expression of SLC40A1 mRNA] |
CTD |
PMID:20090884 |
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NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481
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G |
Slc7a11 |
solute carrier family 7 member 11 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of SLC7A11 protein |
CTD |
PMID:31226288 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Slc7a5 |
solute carrier family 7 member 5 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Vehicle Emissions results in increased expression of SLC7A5 mRNA] |
CTD |
PMID:26621329 |
|
NCBI chr19:49,935,220...49,963,823
Ensembl chr19:49,935,220...49,963,823
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G |
Snca |
synuclein alpha |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [FGF2 protein results in increased expression of SNCA protein] |
CTD |
PMID:12562524 |
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NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Cycloheximide results in increased expression of SOCS3 mRNA] |
CTD |
PMID:23237828 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Paclitaxel results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [SOD2 protein results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vinblastine results in increased expression of SOD2 mRNA]; Dactinomycin inhibits the reaction [Vincristine results in increased expression of SOD2 mRNA]; SOD2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] Dactinomycin inhibits the reaction [polysaccharide-K results in increased expression of SOD2] Dactinomycin inhibits the reaction [[2,2'-(hydroxynitrosohydrazono)bis-ethanamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA] |
CTD |
PMID:9852137 PMID:11154046 PMID:11880364 PMID:12031898 PMID:14996425 PMID:15683720 More...
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sos1 |
SOS Ras/Rac guanine nucleotide exchange factor 1 |
decreases expression |
ISO |
Dactinomycin results in decreased expression of SOS1 mRNA |
CTD |
PMID:16001973 |
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NCBI chr 6:14,533,870...14,613,348
Ensembl chr 6:14,533,360...14,611,107
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G |
Sox17 |
SRY-box transcription factor 17 |
decreases localization |
ISO |
Dactinomycin results in decreased localization of SOX17 protein |
CTD |
PMID:24154490 |
|
NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228
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G |
Spata18 |
spermatogenesis associated 18 |
increases expression |
ISO |
Dactinomycin results in increased expression of SPATA18 mRNA |
CTD |
PMID:21527772 |
|
NCBI chr14:34,531,931...34,558,671
Ensembl chr14:34,531,061...34,558,687
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G |
Sqstm1 |
sequestosome 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Ethanol results in decreased expression of SQSTM1 protein] Dactinomycin inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 mRNA] |
CTD |
PMID:24095927 PMID:25301941 |
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NCBI chr10:34,525,517...34,536,685
Ensembl chr10:34,525,519...34,536,673
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G |
Stat1 |
signal transducer and activator of transcription 1 |
increases expression |
ISO |
Dactinomycin results in increased expression of STAT1 mRNA |
CTD |
PMID:16001973 |
|
NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
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G |
Stmn3 |
stathmin 3 |
increases expression |
ISO |
Dactinomycin results in increased expression of STMN3 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 3:168,416,810...168,424,946
Ensembl chr 3:168,416,810...168,425,056
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G |
Stom |
stomatin |
increases expression |
ISO |
Dactinomycin results in increased expression of STOM mRNA |
CTD |
PMID:21527772 |
|
NCBI chr 3:18,645,058...18,667,343
Ensembl chr 3:18,644,378...18,667,354
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G |
Sult1a1 |
sulfotransferase family 1A member 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Gallic Acid results in increased expression of SULT1A1 mRNA] |
CTD |
PMID:16308312 |
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NCBI chr 1:181,272,022...181,276,750
Ensembl chr 1:181,272,023...181,275,562
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G |
Taf15 |
TATA-box binding protein associated factor 15 |
multiple interactions |
ISO |
TAF15 mRNA inhibits the reaction [Dactinomycin results in decreased expression of SIRT1 mRNA] |
CTD |
PMID:35307376 |
|
NCBI chr10:68,272,900...68,304,951
Ensembl chr10:68,272,969...68,304,949
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G |
Tap1 |
transporter 1, ATP binding cassette subfamily B member |
increases expression |
ISO |
Dactinomycin results in increased expression of TAP1 mRNA |
CTD |
PMID:21527772 |
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NCBI chr20:4,656,262...4,666,634
Ensembl chr20:4,656,263...4,666,901
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G |
Tat |
tyrosine aminotransferase |
multiple interactions |
EXP ISO |
Dactinomycin inhibits the reaction [Dexamethasone results in increased activity of TAT protein]; Dactinomycin inhibits the reaction [Dexamethasone results in increased expression of TAT mRNA]; Dactinomycin inhibits the reaction [Ursodeoxycholic Acid promotes the reaction [Dexamethasone results in increased activity of TAT protein]] |
CTD |
PMID:9398635 PMID:20599767 PMID:28483492 |
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NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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G |
Tbx3 |
T-box transcription factor 3 |
multiple interactions |
ISO |
actinomycin D inhibits the reaction [all-trans-retinoic acid increases expression of TBX3 mRNA in melanoma cells] |
RGD |
PMID:22535523 |
RGD:151361117 |
NCBI chr12:36,879,924...36,894,849
Ensembl chr12:36,881,445...36,893,708
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G |
Tcf4 |
transcription factor 4 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of TCF4 mRNA] |
CTD |
PMID:20459685 |
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NCBI chr18:62,941,739...63,288,126
Ensembl chr18:62,943,782...63,284,425
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G |
Tdo2 |
tryptophan 2,3-dioxygenase |
affects activity |
EXP |
Dactinomycin affects the activity of TDO2 protein |
CTD |
PMID:7306070 |
|
NCBI chr 2:167,269,581...167,287,511
Ensembl chr 2:167,269,579...167,287,511
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G |
Testin |
testin gene |
multiple interactions decreases secretion |
EXP |
Dactinomycin inhibits the reaction [Bucladesine results in decreased expression of TESTIN mRNA]; Dactinomycin inhibits the reaction [lonidamine results in increased expression of TESTIN mRNA]; Dactinomycin inhibits the reaction [lonidamine results in increased secretion of TESTIN protein] Dactinomycin results in decreased secretion of TESTIN protein |
CTD |
PMID:11090432 |
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NCBI chr17:3,824,222...3,859,385
Ensembl chr17:3,846,899...3,859,385
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IL1B protein results in increased expression of TGFB1 mRNA]; Dactinomycin inhibits the reaction [IL1B protein results in increased secretion of TGFB1 protein]; Dactinomycin inhibits the reaction [TGFB1 protein results in decreased expression of AHR mRNA] |
CTD |
PMID:9145908 PMID:16365456 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of COL1A1 mRNA]; Dactinomycin inhibits the reaction [TGFB2 protein results in increased expression of FN1 mRNA] |
CTD |
PMID:18253093 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA alternative form]; Dactinomycin inhibits the reaction [IL1B protein results in decreased expression of THRA mRNA] |
CTD |
PMID:17641275 |
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NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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G |
Tiparp |
TCDD-inducible poly(ADP-ribose) polymerase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of TIPARP mRNA] |
CTD |
PMID:12147270 |
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NCBI chr 2:149,753,682...149,780,327
Ensembl chr 2:149,753,682...149,780,327
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G |
Tmeff2 |
transmembrane protein with EGF-like and two follistatin-like domains 2 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Dihydrotestosterone results in increased expression of TMEFF2 mRNA] |
CTD |
PMID:23405127 |
|
NCBI chr 9:50,445,550...50,733,482
Ensembl chr 9:50,436,079...50,733,475
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G |
Tnf |
tumor necrosis factor |
multiple interactions increases response to substance |
ISO EXP |
[Dactinomycin co-treated with TNF protein] results in increased expression of BNIP3 mRNA; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PTGS2 mRNA]; Dactinomycin promotes the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine inhibits the reaction [lipoteichoic acid results in increased expression of TNF mRNA]] [Dactinomycin co-treated with TNF protein] results in increased activity of CASP3 protein; Dactinomycin inhibits the reaction [TNF protein results in increased expression of EDNRB mRNA] [RELA protein co-treated with NFKB1 protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [RELA protein co-treated with REL protein] inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; [TNF co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF co-treated with Dactinomycin] results in increased activity of CASP7 protein; [TNF co-treated with Dactinomycin] results in increased cleavage of PARP1 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP3 protein; [TNF protein co-treated with Dactinomycin] results in increased activity of CASP7 protein; BCL2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; BCL2A1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; BIRC3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; Dactinomycin inhibits the reaction [[IFNG protein co-treated with TNF protein] results in increased expression of RNF213 mRNA]; Dactinomycin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL11 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of CXCL8 mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of HIF1A protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of MYLK protein]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of PAPPA mRNA]; Dactinomycin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA]; Dactinomycin inhibits the reaction [TNF results in increased abundance of Nitric Oxide]; Dactinomycin inhibits the reaction [TNF results in increased expression of BCL2 protein]; Dactinomycin inhibits the reaction [TNF results in increased expression of MCL1 protein]; Dactinomycin inhibits the reaction [Zinc deficiency promotes the reaction [Tetradecanoylphorbol Acetate results in increased expression of TNF protein]]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP3 protein]; Dactinomycin promotes the reaction [TNF results in increased activity of CASP7 protein]; Dactinomycin promotes the reaction [TNF results in increased cleavage of PARP1 protein]; HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; NFKBIA protein inhibits the reaction [HMOX1 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]]; RELA protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; SOD2 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein]; TNFAIP3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:9576062 PMID:10100995 PMID:11592958 PMID:11880364 PMID:12479793 PMID:12812920 PMID:15531761 PMID:15701621 PMID:16338976 PMID:16492401 PMID:18845389 PMID:21496118 PMID:22207076 PMID:23300732 PMID:26278786 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip3 |
TNF alpha induced protein 3 |
multiple interactions |
ISO |
TNFAIP3 protein inhibits the reaction [Dactinomycin results in increased susceptibility to TNF protein] |
CTD |
PMID:11880364 |
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NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282
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G |
Tnfrsf10b |
TNF receptor superfamily member 10b |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B mRNA] |
CTD |
PMID:27484784 |
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NCBI chr15:44,839,818...44,867,582
Ensembl chr15:44,840,386...44,867,467
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G |
Tnfsf10 |
TNF superfamily member 10 |
multiple interactions |
ISO |
[Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP7 protein; [Dactinomycin co-treated with TNFSF10 protein] results in increased activity of CASP9 protein; [Dactinomycin co-treated with TNFSF10 protein] results in increased expression of AIFM1 protein |
CTD |
PMID:17707539 |
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NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
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G |
Tnfsf9 |
TNF superfamily member 9 |
increases expression |
ISO |
Dactinomycin results in increased expression of TNFSF9 mRNA |
CTD |
PMID:21527772 |
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NCBI chr 9:1,944,017...1,946,351
Ensembl chr 9:1,944,017...1,946,345
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G |
Top1 |
DNA topoisomerase I |
increases activity |
ISO |
Dactinomycin results in increased activity of TOP1 protein |
CTD |
PMID:2164630 |
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NCBI chr 3:149,293,658...149,375,405
Ensembl chr 3:149,293,403...149,376,623
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G |
Tp53 |
tumor protein p53 |
multiple interactions increases activity increases expression |
ISO |
Cadmium Chloride inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]; Cadmium inhibits the reaction [Dactinomycin results in increased expression of and results in increased activity of TP53 protein]; Dactinomycin promotes the reaction [MRPL41 protein results in increased stability of and affects the localization of TP53 protein]; Dactinomycin results in increased expression of and affects the localization of TP53 protein; Dactinomycin results in increased expression of and results in increased activity of TP53 protein; Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]; Naloxone inhibits the reaction [Morphine inhibits the reaction [Dactinomycin results in increased expression of TP53 protein modified form]] Actinomycin D inhibits the reaction [Sunitinib increases expression of TP53 mRNA and protein in breast epithelium] Dactinomycin results in increased activity of TP53 protein Dactinomycin results in increased expression of TP53 protein; Dactinomycin results in increased expression of TP53 protein modified form |
CTD RGD |
PMID:10531375 PMID:12807743 PMID:12869419 PMID:12927789 PMID:16024796 PMID:17581298 PMID:20655369 PMID:28870911 More...
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RGD:150537096 |
NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tp53i11 |
tumor protein p53 inducible protein 11 |
multiple interactions decreases expression |
ISO |
Dactinomycin inhibits the reaction [arsenic trioxide results in increased expression of TP53I11 mRNA] Dactinomycin results in decreased expression of TP53I11 mRNA |
CTD |
PMID:19333544 |
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NCBI chr 3:79,144,824...79,160,056
Ensembl chr 3:79,144,895...79,160,050
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G |
Trpv6 |
transient receptor potential cation channel, subfamily V, member 6 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [1,25-dihydroxyvitamin D results in increased expression of TRPV6 mRNA] |
CTD |
PMID:16362534 |
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NCBI chr 4:70,507,347...70,523,013
Ensembl chr 4:70,507,348...70,523,017
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G |
Tuba4a |
tubulin, alpha 4A |
increases expression |
ISO |
Dactinomycin results in increased expression of TUBA4A mRNA |
CTD |
PMID:21527772 |
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NCBI chr 9:76,709,617...76,714,327
Ensembl chr 9:76,709,614...76,713,918
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G |
Txnrd1 |
thioredoxin reductase 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA]; Dactinomycin inhibits the reaction [sulforaphane results in increased expression of TXNRD1 mRNA] |
CTD |
PMID:12663510 PMID:15652504 |
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NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
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G |
Tymp |
thymidine phosphorylase |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [IFNA1 protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [IFNB1 protein results in increased expression of TYMP mRNA]; Dactinomycin inhibits the reaction [IFNG protein results in increased expression of TYMP mRNA]; Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]; tanespimycin inhibits the reaction [Dactinomycin promotes the reaction [salinomycin results in increased expression of TYMP mRNA]] |
CTD |
PMID:15937643 PMID:30796972 |
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NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874 Ensembl chr 7:120,438,770...120,443,874
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G |
Tyr |
tyrosinase |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [Quercetin results in increased activity of TYR protein] Dactinomycin inhibits the reaction [Phenylephrine results in increased activity of TYR protein] |
CTD |
PMID:14717847 PMID:15278367 |
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NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207
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G |
Ube2l3 |
ubiquitin-conjugating enzyme E2L 3 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [beta-Naphthoflavone results in increased expression of UBE2L3 mRNA]; Dactinomycin inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of UBE2L3 mRNA] |
CTD |
PMID:26318284 |
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NCBI chr11:83,797,722...83,838,862
Ensembl chr11:83,797,722...83,838,862
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
multiple interactions |
EXP |
Dactinomycin inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein] |
CTD |
PMID:15545831 |
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NCBI chr14:41,485,033...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein] Dactinomycin inhibits the reaction [TNF protein results in increased expression of VCAM1 mRNA] |
CTD |
PMID:10100995 PMID:12892526 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Vegfa |
vascular endothelial growth factor A |
multiple interactions |
ISO EXP |
Dactinomycin inhibits the reaction [Oxaliplatin results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Tretinoin results in increased expression of VEGFA mRNA] Dactinomycin inhibits the reaction [Cobalt results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Estradiol results in increased expression of VEGFA mRNA alternative form]; Dactinomycin inhibits the reaction [Nickel results in increased expression of VEGFA mRNA]; Dactinomycin inhibits the reaction [Oxygen deficiency results in increased expression of VEGFA mRNA] |
CTD |
PMID:8344219 PMID:10751333 PMID:11641398 PMID:16386082 PMID:18790786 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Vim |
vimentin |
multiple interactions |
ISO |
Dactinomycin inhibits the reaction [Cadmium Chloride results in increased expression of VIM mRNA] |
CTD |
PMID:9044050 |
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NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
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G |
Vmp1 |
vacuole membrane protein 1 |
multiple interactions decreases expression |
ISO |
[Dactinomycin co-treated with fludioxonil] results in decreased expression of VMP1 mRNA; Dactinomycin inhibits the reaction [Dehydroepiandrosterone results in increased expression of VMP1 mRNA]; Dactinomycin inhibits the reaction [N-(2,3-dichloro-4-hydroxyphenyl)-1-methylcyclohexanecarboxamide results in increased expression of VMP1 mRNA] Dactinomycin results in decreased expression of VMP1 mRNA |
CTD |
PMID:23052036 PMID:25969534 |
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NCBI chr10:71,405,058...71,505,045
Ensembl chr10:71,405,452...71,505,007
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G |
Xiap |
X-linked inhibitor of apoptosis |
decreases expression |
ISO |
Dactinomycin results in decreased expression of XIAP protein |
CTD |
PMID:12430140 |
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NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Abca3 |
ATP binding cassette subfamily A member 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ABCA3 mRNA; Bleomycin results in decreased expression of ABCA3 protein |
CTD |
PMID:34425168 |
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NCBI chr10:13,382,439...13,439,748
Ensembl chr10:13,382,540...13,439,745
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G |
Ace |
angiotensin I converting enzyme |
multiple interactions decreases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] |
CTD |
PMID:20581171 |
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NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
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G |
Ace2 |
angiotensin I converting enzyme 2 |
multiple interactions decreases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] |
CTD |
PMID:20581171 |
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NCBI chr X:30,293,597...30,340,961
Ensembl chr X:30,293,589...30,340,977
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression decreases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein Bleomycin results in decreased expression of ACTA2 protein allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein] (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; loganin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of ACTA2 protein]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; morroniside inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA] |
CTD |
PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 PMID:25582705 PMID:25648892 PMID:26520185 PMID:27153807 PMID:27704718 PMID:28694203 PMID:31302203 PMID:31706003 PMID:31901889 PMID:32032644 PMID:34153405 PMID:34425168 PMID:35187969 PMID:35267148 PMID:35279615 PMID:35472619 PMID:35716765 More...
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Actn1 |
actinin, alpha 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ACTN1 protein |
CTD |
PMID:25933445 |
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NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
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G |
Actn4 |
actinin alpha 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ACTN4 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
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G |
Adam17 |
ADAM metallopeptidase domain 17 |
multiple interactions |
ISO |
Bleomycin results in increased expression of and results in increased activity of ADAM17 protein |
CTD |
PMID:22687607 |
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NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
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G |
Adra1b |
adrenoceptor alpha 1B |
decreases expression |
EXP |
Bleomycin results in decreased expression of ADRA1B mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
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G |
Ager |
advanced glycosylation end product-specific receptor |
multiple interactions decreases expression |
EXP |
protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] |
CTD |
PMID:25582705 PMID:25933445 |
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NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
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G |
Agtr1a |
angiotensin II receptor, type 1a |
multiple interactions increases expression |
EXP |
angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] |
CTD |
PMID:20581171 |
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NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Ahsg |
alpha-2-HS-glycoprotein |
increases expression |
EXP |
Bleomycin results in increased expression of AHSG protein |
CTD |
PMID:25933445 |
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NCBI chr11:78,117,903...78,145,956
Ensembl chr11:78,117,918...78,145,999
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation |
ISO |
Bleomycin results in increased phosphorylation of AKT1 protein |
CTD |
PMID:22687607 PMID:26520185 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
increases expression |
EXP |
Bleomycin results in increased expression of ALB protein |
CTD |
PMID:25933445 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ALDH1A1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Aldoc |
aldolase, fructose-bisphosphate C |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein |
CTD |
PMID:29733421 |
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NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
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G |
Angptl3 |
angiopoietin-like 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of ANGPTL3 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ANGPTL3 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ANGPTL3 protein] |
CTD |
PMID:30825431 |
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NCBI chr 5:113,703,007...113,710,044
Ensembl chr 5:113,703,012...113,709,957
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G |
Ankrd1 |
ankyrin repeat domain 1 |
increases expression |
ISO |
Bleomycin results in increased expression of ANKRD1 mRNA |
CTD |
PMID:26345256 |
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NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
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G |
Anp32e |
acidic nuclear phosphoprotein 32 family member E |
increases expression |
EXP |
Bleomycin results in increased expression of ANP32E protein |
CTD |
PMID:25933445 |
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NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054
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G |
Anxa2 |
annexin A2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA2 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Anxa3 |
annexin A3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA3 protein |
CTD |
PMID:25933445 |
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NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
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G |
Anxa4 |
annexin A4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA4 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
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G |
Anxa5 |
annexin A5 |
increases expression |
EXP |
Bleomycin results in increased expression of ANXA5 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
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G |
Anxa6 |
annexin A6 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ANXA6 protein |
CTD |
PMID:25933445 |
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NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
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G |
Anxa7 |
annexin A7 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein |
CTD |
PMID:29733421 |
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NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
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G |
Aqp1 |
aquaporin 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of AQP1 mRNA |
CTD |
PMID:15782499 |
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NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
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G |
Areg |
amphiregulin |
increases expression |
ISO |
Bleomycin results in increased expression of AREG mRNA |
CTD |
PMID:26817844 |
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NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Arg1 |
arginase 1 |
increases expression multiple interactions decreases expression |
ISO |
Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ARG1 protein] |
CTD |
PMID:26345256 PMID:26526764 PMID:30825431 PMID:33647319 |
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NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Atm |
ATM serine/threonine kinase |
multiple interactions increases phosphorylation |
ISO |
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] |
CTD |
PMID:24933654 |
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NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
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G |
Atp5f1b |
ATP synthase F1 subunit beta |
decreases expression |
EXP |
Bleomycin results in decreased expression of ATP5F1B protein |
CTD |
PMID:25933445 |
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NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
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G |
Atp5if1 |
ATP synthase inhibitory factor subunit 1 |
increases expression |
EXP |
Bleomycin results in increased expression of ATPIF1 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
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G |
Atp5me |
ATP synthase membrane subunit e |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein |
CTD |
PMID:29733421 |
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NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
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G |
Atp5po |
ATP synthase peripheral stalk subunit OSCP |
decreases expression |
ISO |
Bleomycin results in decreased expression of ATP5O protein |
CTD |
PMID:29733421 |
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NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
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G |
Atp6v1a |
ATPase H+ transporting V1 subunit A |
multiple interactions decreases expression |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein Bleomycin results in decreased expression of ATP6V1A protein |
CTD |
PMID:29733421 |
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NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
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G |
Avpr1a |
arginine vasopressin receptor 1A |
decreases expression |
EXP |
Bleomycin results in decreased expression of AVPR1A mRNA |
CTD |
PMID:15808516 |
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NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
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G |
Basp1 |
brain abundant, membrane attached signal protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of BASP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions increases expression |
EXP ISO |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA] Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA] Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein |
CTD |
PMID:23656969 PMID:26093215 PMID:32278510 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression increases expression |
EXP ISO |
[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA] Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein] [Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA |
CTD |
PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bcl6b |
BCL6B, transcription repressor |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA |
CTD |
PMID:29733421 |
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NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
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G |
Birc2 |
baculoviral IAP repeat-containing 2 |
decreases response to substance increases expression |
ISO EXP |
BIRC2 protein results in decreased susceptibility to Bleomycin Bleomycin results in increased expression of BIRC2 protein |
CTD |
PMID:10815900 PMID:15371238 |
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NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
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G |
Birc5 |
baculoviral IAP repeat-containing 5 |
increases expression |
ISO |
Bleomycin results in increased expression of BIRC5 mRNA |
CTD |
PMID:26345256 |
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NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
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G |
Blmh |
bleomycin hydrolase |
affects response to substance |
ISO |
BLMH gene polymorphism affects the susceptibility to Bleomycin |
CTD |
PMID:12082022 |
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NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
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G |
Bmp7 |
bone morphogenetic protein 7 |
decreases expression |
ISO |
Bleomycin results in decreased expression of BMP7 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
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G |
Bscl2 |
BSCL2 lipid droplet biogenesis associated, seipin |
increases expression |
ISO |
Bleomycin results in increased expression of BSCL2 mRNA |
CTD |
PMID:22003191 |
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NCBI chr 1:205,731,814...205,743,430
Ensembl chr 1:205,733,872...205,743,421
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G |
C1qb |
complement C1q B chain |
increases expression |
ISO |
Bleomycin results in increased expression of C1QB mRNA |
CTD |
PMID:26345256 |
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NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
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G |
Cald1 |
caldesmon 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CALD1 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
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G |
Calml3 |
calmodulin-like 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CALML3 protein |
CTD |
PMID:25933445 |
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NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
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G |
Calr |
calreticulin |
increases expression |
EXP |
Bleomycin results in increased expression of CALR protein |
CTD |
PMID:25933445 |
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NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
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G |
Calu |
calumenin |
increases expression |
EXP |
Bleomycin results in increased expression of CALU protein |
CTD |
PMID:25933445 |
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NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
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G |
Car1 |
carbonic anhydrase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CA1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
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G |
Car2 |
carbonic anhydrase 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CA2 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
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G |
Carhsp1 |
calcium regulated heat stable protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CARHSP1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
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G |
Casp3 |
caspase 3 |
multiple interactions increases expression increases activity |
EXP ISO |
[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA] [Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein Bleomycin results in increased activity of CASP3 protein |
CTD |
PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 More...
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp8 |
caspase 8 |
multiple interactions |
ISO |
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA |
CTD |
PMID:26800624 |
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NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
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G |
Casp9 |
caspase 9 |
multiple interactions increases activity |
EXP ISO |
Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein [Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA Bleomycin results in increased activity of CASP9 protein |
CTD |
PMID:15371238 PMID:22687607 PMID:26800624 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cast |
calpastatin |
increases expression |
EXP |
Bleomycin results in increased expression of CAST protein |
CTD |
PMID:25933445 |
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NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
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G |
Cat |
catalase |
increases response to substance decreases activity multiple interactions increases expression |
ISO EXP |
CAT protein results in increased susceptibility to Bleomycin Bleomycin results in decreased activity of CAT celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein] IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein] Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein] |
CTD |
PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav1 |
caveolin 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CAV1 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
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G |
Cavin2 |
caveolae associated protein 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CAVIN2 protein |
CTD |
PMID:25933445 |
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NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
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G |
Cbx8 |
chromobox 8 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of CBX8 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CBX8 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr10:104,294,518...104,296,956
Ensembl chr10:104,294,518...104,297,024
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G |
Cckar |
cholecystokinin A receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of CCKAR mRNA |
CTD |
PMID:15808516 |
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NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
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G |
Ccl11 |
C-C motif chemokine ligand 11 |
increases expression decreases expression multiple interactions decreases response to substance |
ISO |
Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein Bleomycin results in decreased expression of CCL11 mRNA CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA] CCL11 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:16314464 PMID:29720568 |
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NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression decreases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CCL12 mRNA Bleomycin results in decreased expression of CCL12 mRNA [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA] |
CTD |
PMID:28434932 PMID:29720568 |
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NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl17 |
C-C motif chemokine ligand 17 |
increases expression |
ISO |
Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein |
CTD |
PMID:26345256 PMID:29175452 |
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NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein Bleomycin results in decreased expression of CCL2 mRNA Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein] |
CTD |
PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 PMID:26520185 PMID:26526764 PMID:29720568 PMID:30033591 PMID:32828905 PMID:33516805 PMID:35112775 More...
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression decreases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of CCL3 mRNA Bleomycin results in decreased expression of CCL3 protein [Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein Bleomycin results in decreased expression of CCL3 mRNA Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA] |
CTD |
PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CCL4 mRNA |
CTD |
PMID:29720568 |
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NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CCL5 mRNA SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA] |
CTD |
PMID:32828905 |
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NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CCL7 mRNA |
CTD |
PMID:29720568 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
increases expression |
ISO |
Bleomycin results in increased expression of CCL6 protein |
CTD |
PMID:29175452 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccn2 |
cellular communication network factor 2 |
multiple interactions increases expression |
ISO |
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of CCN2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of CCN2 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CCN2 protein] Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein |
CTD |
PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 PMID:35654123 More...
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Ccng1 |
cyclin G1 |
increases expression |
ISO |
Bleomycin results in increased expression of CCNG1 mRNA |
CTD |
PMID:26345256 |
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NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
multiple interactions increases expression decreases response to substance |
ISO |
CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA] Bleomycin results in increased expression of CCR2 mRNA CCR2 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:14609568 PMID:29033951 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
increases expression |
ISO |
Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein |
CTD |
PMID:16314464 |
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NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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G |
Ccr5 |
C-C motif chemokine receptor 5 |
affects expression multiple interactions increases expression |
ISO |
Bleomycin affects the expression of CCR5 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCR5 mRNA] |
CTD |
PMID:26345256 PMID:30825431 |
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NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
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G |
Cct8 |
chaperonin containing TCP1 subunit 8 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein |
CTD |
PMID:29733421 |
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NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
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G |
Cd33 |
CD33 molecule |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CD33 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CD33 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 1:93,935,418...93,940,452
Ensembl chr 1:93,930,971...93,950,149
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G |
Cd34 |
CD34 molecule |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CD34 protein] |
CTD |
PMID:30825431 |
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NCBI chr13:106,480,074...106,499,462
Ensembl chr13:106,480,043...106,499,832
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G |
Cd36 |
CD36 molecule |
decreases expression |
ISO |
Bleomycin results in decreased expression of CD36 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cd44 |
CD44 molecule (Indian blood group) |
multiple interactions increases expression |
ISO |
honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein] |
CTD |
PMID:32032644 |
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NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
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G |
Cd86 |
CD86 molecule |
decreases expression |
ISO |
Bleomycin results in decreased expression of CD86 mRNA |
CTD |
PMID:29720568 |
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NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
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G |
Cdc20 |
cell division cycle 20 |
increases expression |
ISO |
Bleomycin results in increased expression of CDC20 mRNA |
CTD |
PMID:26345256 |
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NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
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G |
Cdh1 |
cadherin 1 |
multiple interactions decreases expression |
ISO EXP |
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; MIR100HG mRNA affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein affects the reaction [Bleomycin results in decreased expression of CDH1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]]; pirfenidone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; TH5487 inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein] Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein |
CTD |
PMID:28300665 PMID:28694203 PMID:32032644 PMID:34425168 PMID:35472619 PMID:35654123 More...
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NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
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G |
Cdh2 |
cadherin 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CDH2 protein OGG1 protein affects the reaction [Bleomycin results in increased expression of CDH2 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of CDH2 protein]; TH5487 inhibits the reaction [Bleomycin results in increased expression of CDH2 protein] |
CTD |
PMID:35654123 |
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NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
increases expression |
ISO |
Bleomycin results in increased expression of CDKN1A mRNA |
CTD |
PMID:26345256 PMID:29720568 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cebpb |
CCAAT/enhancer binding protein beta |
increases expression increases response to substance multiple interactions decreases response to substance |
ISO |
Bleomycin results in increased expression of CEBPB mRNA CEBPB protein results in increased susceptibility to Bleomycin CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA] CEBPB gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:17177178 PMID:21998664 |
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NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
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G |
Cemip2 |
cell migration inducing hyaluronidase 2 |
decreases expression |
ISO |
Bleomycin results in decreased expression of CEMIP2 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
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G |
Cenpe |
centromere protein E |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of CENPE mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
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G |
Ces1d |
carboxylesterase 1D |
decreases expression |
EXP |
Bleomycin results in decreased expression of CES1 protein |
CTD |
PMID:25933445 |
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NCBI chr19:13,873,490...13,912,035
Ensembl chr19:13,796,623...13,912,035
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G |
Cfl1 |
cofilin 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CFL1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
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G |
Chek2 |
checkpoint kinase 2 |
increases phosphorylation multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of CHEK2 protein resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein] |
CTD |
PMID:24933654 |
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NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
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G |
Chrnb2 |
cholinergic receptor nicotinic beta 2 subunit |
decreases expression |
EXP |
Bleomycin results in decreased expression of CHRNB2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
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Ckb |
creatine kinase B |
increases expression |
EXP |
Bleomycin results in increased expression of CKB protein |
CTD |
PMID:25933445 |
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NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
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G |
Clcn5 |
chloride voltage-gated channel 5 |
increases expression |
EXP |
Bleomycin results in increased expression of CLCN5 mRNA |
CTD |
PMID:15808516 |
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NCBI chr X:15,185,353...15,339,977
Ensembl chr X:15,185,451...15,334,264
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G |
Cldn4 |
claudin 4 |
increases expression |
ISO |
Bleomycin results in increased expression of CLDN4 mRNA |
CTD |
PMID:26345256 |
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NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
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G |
Clic4 |
chloride intracellular channel 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLIC4 protein |
CTD |
PMID:25933445 |
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NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
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G |
Clic5 |
chloride intracellular channel 5 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLIC5 protein |
CTD |
PMID:25933445 |
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NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427
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G |
Cltc |
clathrin heavy chain |
decreases expression |
EXP |
Bleomycin results in decreased expression of CLTC protein |
CTD |
PMID:25933445 |
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NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
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G |
Cnr1 |
cannabinoid receptor 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CNR1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression decreases expression |
ISO EXP |
[Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein Bleomycin results in decreased expression of COL1A1 protein Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA] |
CTD |
PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 PMID:25933445 PMID:26093215 PMID:26345256 PMID:28300665 PMID:28726637 PMID:29033951 PMID:31302203 PMID:34153405 PMID:34425168 PMID:35187969 More...
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases expression decreases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of COL1A2 mRNA; Bleomycin results in increased expression of COL1A2 protein Bleomycin results in decreased expression of COL1A2 protein MIR100HG mRNA affects the reaction [Bleomycin results in increased expression of COL1A2 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA] |
CTD |
PMID:19147827 PMID:25933445 PMID:35472619 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Col3a1 |
collagen type III alpha 1 chain |
decreases expression multiple interactions increases expression |
EXP ISO |
Bleomycin results in decreased expression of COL3A1 protein honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein] MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA] Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein |
CTD |
PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 |
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NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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G |
Col5a1 |
collagen type V alpha 1 chain |
decreases expression |
EXP |
Bleomycin results in decreased expression of COL5A1 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
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G |
Comp |
cartilage oligomeric matrix protein |
multiple interactions |
ISO |
[S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein |
CTD |
PMID:29033951 |
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NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
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G |
Cp |
ceruloplasmin |
multiple interactions increases expression |
ISO |
tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] |
CTD |
PMID:12624602 |
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NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
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G |
Crip2 |
cysteine-rich protein 2 |
affects expression |
EXP |
Bleomycin affects the expression of CRIP2 protein |
CTD |
PMID:25933445 |
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NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
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G |
Csf2 |
colony stimulating factor 2 |
increases expression decreases expression |
ISO |
Bleomycin results in increased expression of CSF2 protein Bleomycin results in decreased expression of CSF2 mRNA |
CTD |
PMID:18684396 PMID:29720568 |
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NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
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G |
Csf3 |
colony stimulating factor 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of CSF3 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
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G |
Csrp1 |
cysteine and glycine-rich protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of CSRP1 protein |
CTD |
PMID:25933445 |
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NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
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G |
Ctsa |
cathepsin A |
affects expression |
ISO |
Bleomycin affects the expression of CTSA mRNA |
CTD |
PMID:26345256 |
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NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
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G |
Ctsb |
cathepsin B |
affects expression |
ISO |
Bleomycin affects the expression of CTSB mRNA |
CTD |
PMID:26345256 |
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NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
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G |
Ctsh |
cathepsin H |
affects expression |
ISO |
Bleomycin affects the expression of CTSH mRNA |
CTD |
PMID:26345256 |
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NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
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G |
Ctss |
cathepsin S |
increases expression |
ISO |
Bleomycin results in increased expression of CTSS mRNA |
CTD |
PMID:19101991 |
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NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
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G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of CX3CL1 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of CX3CL1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CX3CL1 protein] |
CTD |
PMID:30825431 |
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NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of CXCL10 mRNA [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein Bleomycin results in decreased expression of CXCL10 mRNA |
CTD |
PMID:26345256 PMID:29720568 PMID:33516805 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCL12 mRNA |
CTD |
PMID:29720568 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl13 |
C-X-C motif chemokine ligand 13 |
affects expression |
ISO |
Bleomycin affects the expression of CXCL13 mRNA |
CTD |
PMID:26345256 |
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NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression multiple interactions increases secretion |
ISO EXP |
Bleomycin results in increased expression of CXCL2 protein [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein 3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein] |
CTD |
PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
multiple interactions increases secretion |
ISO |
TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein] |
CTD |
PMID:26600069 |
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NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
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G |
Cxcl9 |
C-X-C motif chemokine ligand 9 |
increases expression |
ISO |
Bleomycin results in increased expression of CXCL9 protein |
CTD |
PMID:29175452 |
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NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
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G |
Cyba |
cytochrome b-245 alpha chain |
multiple interactions increases expression |
ISO |
Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of CYBA mRNA] |
CTD |
PMID:35187969 |
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NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
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G |
Cycs |
cytochrome c, somatic |
affects localization |
EXP |
Bleomycin affects the localization of CYCS protein |
CTD |
PMID:15371238 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
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G |
Dbi |
diazepam binding inhibitor |
increases expression |
EXP |
Bleomycin results in increased expression of DBI protein |
CTD |
PMID:25933445 |
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NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
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G |
Des |
desmin |
increases expression |
EXP |
Bleomycin results in increased expression of DES protein |
CTD |
PMID:25933445 |
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NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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G |
Dlat |
dihydrolipoamide S-acetyltransferase |
decreases expression |
ISO |
Bleomycin results in decreased expression of DLAT protein |
CTD |
PMID:29733421 |
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NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
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G |
Dld |
dihydrolipoamide dehydrogenase |
increases expression |
EXP ISO |
Bleomycin results in increased expression of DLD protein |
CTD |
PMID:25933445 PMID:29733421 |
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NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
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G |
Dlk1 |
delta like non-canonical Notch ligand 1 |
increases expression |
ISO |
Bleomycin results in increased expression of DLK1 protein |
CTD |
PMID:29175452 |
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NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
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G |
Dll4 |
delta like canonical Notch ligand 4 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of DLL4 protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of DLL4 protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931
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G |
Dnmt1 |
DNA methyltransferase 1 |
affects response to substance |
ISO |
DNMT1 protein affects the susceptibility to Bleomycin |
CTD |
PMID:17991895 |
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NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
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G |
Dpep1 |
dipeptidase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of DPEP1 protein |
CTD |
PMID:25933445 |
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NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
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G |
Ech1 |
enoyl-CoA hydratase 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of ECH1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Edn1 |
endothelin 1 |
multiple interactions increases expression |
EXP |
Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] |
CTD |
PMID:26093215 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Eef1a1 |
eukaryotic translation elongation factor 1 alpha 1 |
increases expression |
ISO |
Bleomycin results in increased expression of EEF1A1 protein |
CTD |
PMID:29733421 |
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NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
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G |
Egr1 |
early growth response 1 |
increases expression affects expression multiple interactions |
ISO |
Bleomycin results in increased expression of EGR1 mRNA Bleomycin affects the expression of EGR1 mRNA rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA] |
CTD |
PMID:19147827 PMID:26345256 |
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NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
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G |
Egr2 |
early growth response 2 |
affects expression |
ISO |
Bleomycin affects the expression of EGR2 mRNA |
CTD |
PMID:26345256 |
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NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
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G |
Ehd1 |
EH-domain containing 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of EHD1 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
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G |
Ehd2 |
EH-domain containing 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of EHD2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
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G |
Eif5a |
eukaryotic translation initiation factor 5A |
increases expression |
EXP |
Bleomycin results in increased expression of EIF5A protein |
CTD |
PMID:25933445 |
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NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
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G |
Eln |
elastin |
increases expression |
ISO |
Bleomycin results in increased expression of ELN mRNA |
CTD |
PMID:26817844 |
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NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
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G |
Emcn |
endomucin |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of EMCN mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of EMCN mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 2:225,891,100...225,970,932
Ensembl chr 2:225,891,100...225,970,929
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G |
Eng |
endoglin |
multiple interactions increases expression |
ISO |
Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of ENG protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230
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G |
Epx |
eosinophil peroxidase |
increases expression |
EXP |
Bleomycin results in increased expression of EPX protein |
CTD |
PMID:26093215 |
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NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
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G |
Errfi1 |
ERBB receptor feedback inhibitor 1 |
decreases expression |
ISO |
Bleomycin results in decreased expression of ERRFI1 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
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G |
Espl1 |
extra spindle pole bodies like 1, separase |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of ESPL1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 7:133,424,027...133,450,984
Ensembl chr 7:133,424,130...133,450,984
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
ISO |
Bleomycin results in decreased expression of ETS1 mRNA |
CTD |
PMID:28726637 |
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NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Ets2 |
ETS proto-oncogene 2, transcription factor |
decreases expression |
ISO |
Bleomycin results in decreased expression of ETS2 mRNA |
CTD |
PMID:28726637 |
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NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
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G |
Ezr |
ezrin |
decreases expression |
EXP |
Bleomycin results in decreased expression of EZR protein |
CTD |
PMID:25933445 |
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NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
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G |
F2rl1 |
F2R like trypsin receptor 1 |
multiple interactions increases expression |
EXP |
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein] Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein |
CTD |
PMID:23656969 |
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NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
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G |
Fabp4 |
fatty acid binding protein 4 |
decreases expression |
ISO |
Bleomycin results in decreased expression of FABP4 mRNA |
CTD |
PMID:29408570 |
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NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
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G |
Faslg |
Fas ligand |
increases expression |
ISO |
Bleomycin results in increased expression of FASLG mRNA |
CTD |
PMID:11350791 |
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NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
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G |
Fgf1 |
fibroblast growth factor 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FGF1 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF1 protein] |
CTD |
PMID:30825431 |
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NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
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G |
Fgf2 |
fibroblast growth factor 2 |
increases expression multiple interactions |
EXP ISO |
Bleomycin results in increased expression of FGF2 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF2 protein] protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein] |
CTD |
PMID:25582705 PMID:30825431 |
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NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
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G |
Fgf21 |
fibroblast growth factor 21 |
decreases expression multiple interactions |
ISO |
Bleomycin results in decreased expression of FGF21 protein Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of FGF21 protein] |
CTD |
PMID:30825431 |
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NCBI chr 1:96,083,495...96,084,738
Ensembl chr 1:96,083,441...96,090,454
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G |
Fgf7 |
fibroblast growth factor 7 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FGF7 protein Cannabidiol analog promotes the reaction [Bleomycin results in increased expression of FGF7 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of FGF7 protein] |
CTD |
PMID:30825431 |
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NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929
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G |
Fhl1 |
four and a half LIM domains 1 |
increases expression |
EXP |
Bleomycin results in increased expression of FHL1 protein |
CTD |
PMID:25933445 |
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NCBI chr X:134,555,399...134,614,930
Ensembl chr X:134,555,479...134,614,928
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G |
Fn1 |
fibronectin 1 |
increases expression multiple interactions |
EXP ISO |
Bleomycin results in increased expression of FN1 protein Bleomycin results in increased expression of FN1 mRNA Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein [Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein affects the reaction [Bleomycin results in increased expression of FN1 protein]; OGG1 protein inhibits the reaction [TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]]; OGG1 protein promotes the reaction [Bleomycin results in increased expression of FN1 protein]; pirfenidone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]; TH5487 inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Thioctic Acid inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA] |
CTD |
PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 PMID:31302203 PMID:32032644 PMID:34460027 PMID:35187969 PMID:35267148 PMID:35654123 More...
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NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
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G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases activity |
ISO |
Bleomycin results in increased activity of FOS protein |
CTD |
PMID:12003776 |
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NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
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G |
Foxp3 |
forkhead box P3 |
increases expression |
ISO |
Bleomycin results in increased expression of FOXP3 mRNA |
CTD |
PMID:29033951 |
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NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838
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G |
Fshr |
follicle stimulating hormone receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of FSHR mRNA |
CTD |
PMID:15808516 |
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NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
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G |
Fubp1 |
far upstream element binding protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of FUBP1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
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G |
Fzd6 |
frizzled class receptor 6 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of FZD6 mRNA MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA] |
CTD |
PMID:28726637 |
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NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
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G |
Gabra4 |
gamma-aminobutyric acid type A receptor subunit alpha 4 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRA4 mRNA |
CTD |
PMID:15808516 |
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NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
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G |
Gabrb2 |
gamma-aminobutyric acid type A receptor subunit beta 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRB2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
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G |
Gabrg2 |
gamma-aminobutyric acid type A receptor subunit gamma 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRG2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
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G |
Gabrr1 |
gamma-aminobutyric acid type A receptor subunit rho 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GABRR1 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
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G |
Ganab |
glucosidase II alpha subunit |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein |
CTD |
PMID:29733421 |
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NCBI chr 1:205,793,810...205,813,701
Ensembl chr 1:205,793,895...205,813,695
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G |
Gas6 |
growth arrest specific 6 |
increases expression |
ISO |
Bleomycin results in increased expression of GAS6 protein |
CTD |
PMID:29175452 |
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NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
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G |
Gata3 |
GATA binding protein 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of GATA3 mRNA S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA] |
CTD |
PMID:29033951 |
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NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
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G |
Gc |
GC, vitamin D binding protein |
increases expression |
EXP |
Bleomycin results in increased expression of GC protein |
CTD |
PMID:25933445 |
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NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions decreases expression |
ISO |
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] |
CTD |
PMID:23570914 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gda |
guanine deaminase |
decreases expression |
EXP |
Bleomycin results in decreased expression of GDA protein |
CTD |
PMID:25933445 |
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NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
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G |
Gpi |
glucose-6-phosphate isomerase |
decreases expression |
EXP |
Bleomycin results in decreased expression of GPI protein |
CTD |
PMID:25933445 |
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NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
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G |
Gpx1 |
glutathione peroxidase 1 |
affects expression |
EXP |
Bleomycin affects the expression of GPX1 protein |
CTD |
PMID:25933445 |
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NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Gria2 |
glutamate ionotropic receptor AMPA type subunit 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRIA2 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
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G |
Grik3 |
glutamate ionotropic receptor kainate type subunit 3 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRIK3 mRNA |
CTD |
PMID:15808516 |
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NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
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G |
Grpr |
gastrin releasing peptide receptor |
decreases expression |
EXP |
Bleomycin results in decreased expression of GRPR mRNA |
CTD |
PMID:15808516 |
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NCBI chr X:30,998,425...31,038,442
Ensembl chr X:30,998,416...31,038,442
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions increases phosphorylation |
ISO |
[2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] |
CTD |
PMID:19429264 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsn |
gelsolin |
decreases expression |
EXP |
Bleomycin results in decreased expression of GSN protein |
CTD |
PMID:25933445 |
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NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
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G |
Gsr |
glutathione-disulfide reductase |
decreases activity multiple interactions |
EXP |
Bleomycin results in decreased activity of GSR protein celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein] |
CTD |
PMID:26768587 |
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NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
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G |
Gstm1 |
glutathione S-transferase mu 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of GSTM1 protein |
CTD |
PMID:25933445 |
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NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
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G |
H1f0 |
H1.0 linker histone |
affects expression |
EXP |
Bleomycin affects the expression of H1F0 protein |
CTD |
PMID:25933445 |
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NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
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G |
H1f4 |
H1.4 linker histone, cluster member |
affects expression |
EXP |
Bleomycin affects the expression of H1F4 protein |
CTD |
PMID:25933445 |
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NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
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G |
H2ax |
H2A.X variant histone |
increases expression |
ISO |
Bleomycin results in increased expression of H2AX protein |
CTD |
PMID:25130544 |
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NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
decreases expression |
EXP |
Bleomycin results in decreased expression of HADHA protein |
CTD |
PMID:25933445 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of HAVCR1 protein |
CTD |
PMID:29175452 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hbb |
hemoglobin subunit beta |
affects expression |
EXP |
Bleomycin affects the expression of HBB protein |
CTD |
PMID:25933445 |
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NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbb-b2 |
hemoglobin, beta adult minor chain |
affects expression |
EXP |
Bleomycin affects the expression of HBB-B2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:158,243,696...158,245,091
Ensembl chr 1:158,120,200...158,252,012
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G |
Hbegf |
heparin-binding EGF-like growth factor |
increases expression |
ISO |
Bleomycin results in increased expression of HBEGF mRNA |
CTD |
PMID:18684396 |
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NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
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G |
Hcls1 |
hematopoietic cell specific Lyn substrate 1 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of HCLS1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr11:63,817,482...63,840,943
Ensembl chr11:63,817,476...63,841,014
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G |
Hgf |
hepatocyte growth factor |
decreases expression multiple interactions increases expression increases secretion |
EXP ISO |
Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of HGF protein]; lenabasum promotes the reaction [Bleomycin results in decreased expression of HGF protein] Bleomycin results in increased expression of HGF mRNA Bleomycin results in increased secretion of HGF protein Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein] |
CTD |
PMID:16115399 PMID:22687607 PMID:29408570 PMID:30825431 |
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NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
[HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] |
CTD |
PMID:28434932 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hist1h2bg |
histone cluster 1, H2bg |
decreases expression |
EXP |
Bleomycin results in decreased expression of HIST1H2BG protein |
CTD |
PMID:25933445 |
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NCBI chr17:41,571,278...41,571,658
Ensembl chr17:41,571,210...41,571,896
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G |
Hmces |
5-hydroxymethylcytosine binding, ES cell specific |
decreases expression |
ISO |
Bleomycin results in decreased expression of HMCES mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:120,392,812...120,415,616
Ensembl chr 4:120,366,542...120,415,616
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G |
Hmgb1 |
high mobility group box 1 |
multiple interactions increases expression |
EXP ISO |
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein] Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA] |
CTD |
PMID:25582705 PMID:32278510 |
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NCBI chr12:5,973,062...5,978,565
Ensembl chr12:5,901,586...5,978,565
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of HMOX1 protein celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA] PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein] |
CTD |
PMID:16317386 PMID:26093215 PMID:26768587 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnrnpa2b1 |
heterogeneous nuclear ribonucleoprotein A2/B1 |
increases expression |
EXP |
Bleomycin results in increased expression of HNRNPA2B1 protein |
CTD |
PMID:25933445 |
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NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
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G |
Hnrnpa3 |
heterogeneous nuclear ribonucleoprotein A3 |
increases expression |
EXP |
Bleomycin results in increased expression of HNRNPA3 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
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G |
Hpx |
hemopexin |
increases expression |
EXP |
Bleomycin results in increased expression of HPX protein |
CTD |
PMID:25933445 |
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NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
multiple interactions |
EXP |
[Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein |
CTD |
PMID:24478030 |
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NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Hsp90b1 |
heat shock protein 90 beta family member 1 |
multiple interactions |
EXP |
[Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein |
CTD |
PMID:24478030 |
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NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression |
EXP |
Bleomycin results in increased expression of HSPA5 protein |
CTD |
PMID:25933445 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of HSPB1 protein |
CTD |
PMID:25933445 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Hspe1 |
heat shock protein family E (Hsp10) member 1 |
increases expression |
EXP ISO |
Bleomycin results in increased expression of HSPE1 protein |
CTD |
PMID:25933445 PMID:29733421 |
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NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
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G |
Htr1f |
5-hydroxytryptamine receptor 1F |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR1F mRNA |
CTD |
PMID:15808516 |
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NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
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G |
Htr5a |
5-hydroxytryptamine receptor 5A |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR5A mRNA |
CTD |
PMID:15808516 |
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NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
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G |
Htr5b |
5-hydroxytryptamine (serotonin) receptor 5B |
decreases expression |
EXP |
Bleomycin results in decreased expression of HTR5B mRNA |
CTD |
PMID:15808516 |
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NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835
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G |
Icam1 |
intercellular adhesion molecule 1 |
increases expression |
ISO |
Bleomycin results in increased expression of ICAM1 mRNA |
CTD |
PMID:29033951 PMID:29720568 |
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NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
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G |
Idh2 |
isocitrate dehydrogenase (NADP(+)) 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of IDH2 protein |
CTD |
PMID:25933445 |
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NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
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G |
Ifitm1 |
interferon induced transmembrane protein 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of IFITM1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IFITM1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 1:196,067,163...196,069,169
Ensembl chr 1:196,067,963...196,069,169
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G |
Ifng |
interferon gamma |
increases expression multiple interactions decreases expression |
ISO EXP |
Bleomycin results in increased expression of IFNG mRNA [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein Bleomycin results in decreased expression of IFNG protein [SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein Bleomycin results in decreased expression of IFNG mRNA |
CTD |
PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 |
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NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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G |
Igf1 |
insulin-like growth factor 1 |
increases expression |
ISO |
Bleomycin results in increased expression of IGF1 mRNA |
CTD |
PMID:1705203 |
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NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
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G |
Il10 |
interleukin 10 |
increases expression |
ISO |
Bleomycin results in increased expression of IL10 protein |
CTD |
PMID:29175452 |
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NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il12b |
interleukin 12B |
increases expression |
ISO |
Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein |
CTD |
PMID:11350791 |
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NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
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G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
increases expression |
ISO |
Bleomycin results in increased expression of IL12RB2 mRNA |
CTD |
PMID:11350791 |
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NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
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G |
Il13 |
interleukin 13 |
decreases response to substance multiple interactions |
ISO |
IL13 gene mutant form results in decreased susceptibility to Bleomycin IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA] |
CTD |
PMID:15322207 |
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NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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G |
Il13ra1 |
interleukin 13 receptor subunit alpha 1 |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of IL13RA1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr X:115,348,860...115,408,682
Ensembl chr X:115,348,860...115,408,681
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G |
Il17a |
interleukin 17A |
multiple interactions increases expression |
ISO |
Curcumin inhibits the reaction [Bleomycin results in increased expression of IL17A mRNA] |
CTD |
PMID:35716765 |
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NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889
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G |
Il1a |
interleukin 1 alpha |
multiple interactions increases expression |
ISO |
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein] Bleomycin results in increased expression of IL1A protein |
CTD |
PMID:8317554 PMID:29175452 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression increases secretion affects expression |
ISO EXP |
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; [Bleomycin co-treated with Cannabidiol analog] results in decreased expression of IL1B mRNA; [Bleomycin co-treated with Rosiglitazone] results in decreased expression of IL1B mRNA; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein] Bleomycin affects the expression of IL1B mRNA IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein] Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein] |
CTD |
PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 PMID:17177178 PMID:19147827 PMID:22687607 PMID:26093215 PMID:26520185 PMID:26526764 PMID:26600069 PMID:27704718 PMID:28300665 PMID:28694203 PMID:30033591 PMID:32032644 PMID:32828905 PMID:35267148 More...
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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Il2 |
interleukin 2 |
multiple interactions |
EXP |
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein |
CTD |
PMID:33516805 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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Il4 |
interleukin 4 |
increases expression affects response to substance multiple interactions decreases response to substance |
ISO |
Bleomycin results in increased expression of IL4 mRNA IL4 protein affects the susceptibility to Bleomycin Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA]; IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL4 mRNA] IL4 gene mutant form results in decreased susceptibility to Bleomycin |
CTD |
PMID:11554783 PMID:12574379 PMID:15322207 PMID:30033591 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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Il6 |
interleukin 6 |
increases expression multiple interactions |
ISO EXP |
Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein] allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein] |
CTD |
PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 PMID:26209236 PMID:26520185 PMID:28300665 PMID:28850077 PMID:30033591 PMID:32032644 PMID:35267148 PMID:35716765 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Insig1 |
insulin induced gene 1 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of INSIG1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952
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Itgb2 |
integrin subunit beta 2 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of ITGB2 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ITGB2 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr20:11,061,394...11,097,656
Ensembl chr20:11,061,430...11,097,600
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Jpt1 |
Jupiter microtubule associated homolog 1 |
increases expression |
EXP |
Bleomycin results in increased expression of JPT1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
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Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases activity multiple interactions increases phosphorylation |
ISO |
Bleomycin results in increased activity of JUN protein Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of JUN protein] |
CTD |
PMID:12003776 PMID:35716765 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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Keap1 |
Kelch-like ECH-associated protein 1 |
decreases expression multiple interactions |
EXP |
Bleomycin results in decreased expression of KEAP1 protein celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein] |
CTD |
PMID:26768587 |
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NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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Khsrp |
KH-type splicing regulatory protein |
increases expression |
EXP |
Bleomycin results in increased expression of KHSRP protein |
CTD |
PMID:25933445 |
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NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
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Kit |
KIT proto-oncogene receptor tyrosine kinase |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of KIT protein [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein |
CTD |
PMID:29733421 |
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NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
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Kl |
Klotho |
decreases expression |
ISO |
Bleomycin results in decreased expression of KL mRNA |
CTD |
PMID:29408570 |
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NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
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Klhl42 |
kelch-like family, member 42 |
increases expression |
ISO |
Bleomycin results in increased expression of KLHL42 mRNA |
CTD |
PMID:33770205 |
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NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
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G |
Kras |
KRAS proto-oncogene, GTPase |
multiple interactions |
ISO |
[Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene |
CTD |
PMID:12616606 |
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NCBI chr 4:178,185,418...178,218,484
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Krt19 |
keratin 19 |
decreases expression |
EXP |
Bleomycin results in decreased expression of KRT19 protein |
CTD |
PMID:25933445 |
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NCBI chr10:85,075,835...85,080,552
Ensembl chr10:85,066,802...85,171,799
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Lap3 |
leucine aminopeptidase 3 |
increases expression |
EXP |
Bleomycin results in increased expression of LAP3 protein |
CTD |
PMID:25933445 |
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NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
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Lasp1 |
LIM and SH3 protein 1 |
increases expression |
EXP |
Bleomycin results in increased expression of LASP1 protein |
CTD |
PMID:25933445 |
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NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
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Lcn2 |
lipocalin 2 |
increases expression |
ISO |
Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein |
CTD |
PMID:26345256 |
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NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lcp1 |
lymphocyte cytosolic protein 1 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LCP1 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LCP1 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr15:50,443,300...50,544,682
Ensembl chr15:50,488,149...50,544,680
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Lep |
leptin |
increases expression |
ISO |
Bleomycin results in increased expression of LEP protein |
CTD |
PMID:29175452 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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Lgals3 |
galectin 3 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LGALS3 protein NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein] |
CTD |
PMID:26526764 |
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NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
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Lgals9 |
galectin 9 |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of LGALS9 mRNA Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LGALS9 mRNA] |
CTD |
PMID:30825431 |
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NCBI chr10:63,907,018...63,930,224
Ensembl chr10:63,907,018...63,930,045
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G |
Lhfpl6 |
LHFPL tetraspan subfamily member 6 |
multiple interactions decreases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of LHFP mRNA]; lenabasum inhibits the reaction [Bleomycin results in decreased expression of LHFP mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 2:137,126,485...137,324,442
Ensembl chr 2:137,126,509...137,324,443
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G |
Lhx1 |
LIM homeobox 1 |
multiple interactions |
ISO |
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA |
CTD |
PMID:29733421 |
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NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
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G |
Liph |
lipase H |
decreases expression |
ISO |
Bleomycin results in decreased expression of LIPH mRNA |
CTD |
PMID:33770205 |
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NCBI chr11:79,032,229...79,081,625
Ensembl chr11:79,033,312...79,081,625
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Lmna |
lamin A/C |
increases expression |
EXP |
Bleomycin results in increased expression of LMNA protein |
CTD |
PMID:25933445 |
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NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
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Lpxn |
leupaxin |
multiple interactions increases expression |
ISO |
Cannabidiol analog inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA]; lenabasum inhibits the reaction [Bleomycin results in increased expression of LPXN mRNA] |
CTD |
PMID:30825431 |
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NCBI chr 1:209,928,297...209,963,085
Ensembl chr 1:209,929,202...209,963,084
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G |
Lyz2 |
lysozyme 2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of LYZ protein |
CTD |
PMID:25933445 |
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NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
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Macroh2a1 |
macroH2A.1 histone |
decreases expression |
EXP |
Bleomycin results in decreased expression of MACROH2A1 protein |
CTD |
PMID:25933445 |
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NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
increases expression multiple interactions |
ISO |
Bleomycin results in increased expression of MAP1LC3B protein modified form Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form] |
CTD |
PMID:31302203 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] |
CTD |
PMID:23570914 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions |
ISO |
Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] |
CTD |
PMID:23570914 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation |
ISO |
Curcumin inhibits the reaction [Bleomycin results in increased phosphorylation of MAPK8 protein] |
CTD |
PMID:35716765 |
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NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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G |
Marcks |
myristoylated alanine rich protein kinase C substrate |
decreases expression |
EXP |
Bleomycin results in decreased expression of MARCKS protein |
CTD |
PMID:25933445 |
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NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
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G |
Mdh2 |
malate dehydrogenase 2 |
decreases expression multiple interactions |
EXP ISO |
Bleomycin results in decreased expression of MDH2 protein [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein |
CTD |
PMID:25933445 PMID:29733421 |
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NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
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G |
Mecp2 |
methyl CpG binding protein 2 |
affects response to substance |
ISO |
MECP2 protein affects the susceptibility to Bleomycin |
CTD |
PMID:21435439 |
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NCBI chr X:151,781,177...151,844,687
Ensembl chr X:151,789,930...151,844,689
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Mepce |
methylphosphate capping enzyme |
increases expression |
ISO |
Bleomycin results in increased expression of MEPCE mRNA |
CTD |
PMID:33770205 |
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NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
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G |
Mertk |
MER proto-oncogene, tyrosine kinase |
multiple interactions increases phosphorylation |
ISO |
Bleomycin affects the localization of and affects the expression of MERTK protein Bleomycin results in increased phosphorylation of MERTK protein |
CTD |
PMID:22687607 |
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NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
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Mif |
macrophage migration inhibitory factor |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIF protein |
CTD |
PMID:25933445 |
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NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
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Mir100 |
microRNA 100 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR100 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
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G |
Mir101-2 |
microRNA 101-2 |
decreases expression |
EXP ISO |
Bleomycin results in decreased expression of MIR101B mRNA |
CTD |
PMID:25933445 PMID:28726637 |
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NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
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G |
Mir101a |
microRNA 101a |
multiple interactions decreases expression |
ISO EXP |
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA] Bleomycin results in decreased expression of MIR101A mRNA |
CTD |
PMID:25933445 PMID:28726637 |
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NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
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Mir106b |
microRNA 106b |
affects expression |
EXP |
Bleomycin affects the expression of MIR106B mRNA |
CTD |
PMID:25933445 |
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NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
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G |
Mir107 |
microRNA 107 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR107 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
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G |
Mir10a |
microRNA 10a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR10A mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
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G |
Mir10b |
microRNA 10b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR10B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
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G |
Mir1224 |
microRNA 1224 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR1224 mRNA |
CTD |
PMID:25933445 |
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NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
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G |
Mir1249 |
microRNA 1249 |
affects expression |
EXP |
Bleomycin affects the expression of MIR1249 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
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G |
Mir125a |
microRNA 125a |
affects expression |
EXP |
Bleomycin affects the expression of MIR125A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
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G |
Mir126b |
microRNA 126b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR126 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 3:9,415,087...9,415,159
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Mir130a |
microRNA 130a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR130A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
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G |
Mir133a1 |
microRNA 133a-1 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR133A1 mRNA |
CTD |
PMID:25933445 |
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NCBI chr18:1,885,082...1,885,168
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Mir133b |
microRNA 133b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR133B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
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G |
Mir140 |
microRNA 140 |
affects expression |
EXP |
Bleomycin affects the expression of MIR140 mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
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G |
Mir141 |
microRNA 141 |
affects expression |
EXP |
Bleomycin affects the expression of MIR141 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
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G |
Mir142 |
microRNA 142 |
decreases expression increases expression |
EXP |
Bleomycin results in decreased expression of MIR142 mRNA Bleomycin results in increased expression of MIR142 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
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G |
Mir143 |
microRNA 143 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR143 mRNA |
CTD |
PMID:25933445 |
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NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
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G |
Mir144 |
microRNA 144 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR144 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
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G |
Mir145 |
microRNA 145 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR145 mRNA |
CTD |
PMID:25933445 |
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NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
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G |
Mir146a |
microRNA 146a |
affects expression |
EXP |
Bleomycin affects the expression of MIR146A mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
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G |
Mir146b |
microRNA 146b |
increases expression |
EXP |
Bleomycin results in increased expression of MIR146B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
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G |
Mir148b |
microRNA 148b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR148B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
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Mir150 |
microRNA 150 |
affects expression |
EXP |
Bleomycin affects the expression of MIR150 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
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Mir151 |
microRNA 151 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR151 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:105,172,377...105,172,473
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Mir152 |
microRNA 152 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR152 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
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Mir15b |
microRNA 15b |
affects expression |
EXP |
Bleomycin affects the expression of MIR15B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
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Mir16 |
microRNA 16 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR16 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
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Mir17 |
microRNA 17 |
affects expression |
EXP |
Bleomycin affects the expression of MIR17 mRNA |
CTD |
PMID:25933445 |
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NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
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Mir181c |
microRNA 181c |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR181C mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
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Mir181d |
microRNA 181d |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR181D mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
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Mir183 |
microRNA 183 |
affects expression |
EXP |
Bleomycin affects the expression of MIR183 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
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Mir185 |
microRNA 185 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR185 mRNA |
CTD |
PMID:25933445 |
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NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
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Mir186 |
microRNA 186 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR186 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
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Mir188 |
microRNA 188 |
affects expression |
EXP |
Bleomycin affects the expression of MIR188 mRNA |
CTD |
PMID:25933445 |
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NCBI chr X:15,247,715...15,247,794
Ensembl chr X:15,247,715...15,247,794
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Mir18a |
microRNA 18a |
increases expression |
EXP |
Bleomycin results in increased expression of MIR18A mRNA |
CTD |
PMID:25933445 |
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NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
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Mir193 |
microRNA 193 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR193 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:64,672,354...64,672,439
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Mir195 |
microRNA 195 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR195 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
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Mir199a2 |
microRNA 199a-2 |
affects expression |
EXP |
Bleomycin affects the expression of MIR199A2 mRNA |
CTD |
PMID:25933445 |
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NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
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Mir19a |
microRNA 19a |
affects expression |
EXP |
Bleomycin affects the expression of MIR19A mRNA |
CTD |
PMID:25933445 |
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NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
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Mir200a |
microRNA 200a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 5:166,648,494...166,648,582
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Mir200b |
microRNA 200b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
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Mir200c |
microRNA 200c |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR200C mRNA |
CTD |
PMID:25933445 |
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NCBI chr 4:157,523,679...157,523,747
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Mir204 |
microRNA 204 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR204 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
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Mir20a |
microRNA 20a |
affects expression |
EXP |
Bleomycin affects the expression of MIR20A mRNA |
CTD |
PMID:25933445 |
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NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
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Mir20b |
microRNA 20b |
affects expression |
EXP |
Bleomycin affects the expression of MIR20B mRNA |
CTD |
PMID:25933445 |
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NCBI chr X:132,422,211...132,422,282
Ensembl chr X:132,422,211...132,422,282
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Mir21 |
microRNA 21 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR21 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
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Mir210 |
microRNA 210 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR210 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:196,326,343...196,326,452
Ensembl chr 1:196,326,337...196,326,454
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Mir211 |
microRNA 211 |
affects expression |
EXP |
Bleomycin affects the expression of MIR211 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644
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Mir212 |
microRNA 212 |
affects expression |
EXP |
Bleomycin affects the expression of MIR212 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
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Mir214 |
microRNA 214 |
affects expression |
EXP |
Bleomycin affects the expression of MIR214 mRNA |
CTD |
PMID:25933445 |
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NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481
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Mir22 |
microRNA 22 |
affects expression |
EXP |
Bleomycin affects the expression of MIR22 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
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Mir221 |
microRNA 221 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR221 mRNA |
CTD |
PMID:25933445 |
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NCBI chr X:3,429,465...3,429,573
Ensembl chr X:3,429,465...3,429,573
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Mir222 |
microRNA 222 |
decreases expression affects expression |
EXP |
Bleomycin results in decreased expression of MIR222 mRNA Bleomycin affects the expression of MIR222 mRNA |
CTD |
PMID:25933445 PMID:34425168 |
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NCBI chr X:3,428,904...3,429,006
Ensembl chr X:3,428,904...3,429,006
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Mir223 |
microRNA 223 |
affects expression |
EXP |
Bleomycin affects the expression of MIR223 mRNA |
CTD |
PMID:25933445 |
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NCBI chr X:61,141,887...61,141,996
Ensembl chr X:61,141,887...61,141,996
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Mir23a |
microRNA 23a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR23A mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
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Mir23b |
microRNA 23b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR23B mRNA |
CTD |
PMID:25933445 |
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NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
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Mir24-2 |
microRNA 24-2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR24-2 mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790
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Mir25 |
microRNA 25 |
affects expression |
EXP |
Bleomycin affects the expression of MIR25 mRNA |
CTD |
PMID:25933445 |
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NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
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Mir26a |
microRNA 26a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR26A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
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Mir26b |
microRNA 26b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR26B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
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Mir27a |
microRNA 27a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR27A mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
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Mir27b |
microRNA 27b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR27B mRNA |
CTD |
PMID:25933445 |
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NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
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Mir28 |
microRNA 28 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR28 mRNA |
CTD |
PMID:25933445 |
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NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
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Mir290 |
microRNA 290 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR290 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728
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Mir296 |
microRNA 296 |
affects expression |
EXP |
Bleomycin affects the expression of MIR296 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
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Mir2985 |
microRNA 2985 |
affects expression |
EXP |
Bleomycin affects the expression of MIR2985 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 2:165,956,389...165,956,498
Ensembl chr 2:165,956,389...165,956,498
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Mir29a |
microRNA 29a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR29A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 4:59,650,608...59,650,695
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Mir301a |
microRNA 301a |
affects expression |
EXP |
Bleomycin affects the expression of MIR301A mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435
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Mir30a |
microRNA 30a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30A mRNA |
CTD |
PMID:25933445 |
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NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
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Mir30b |
microRNA 30b |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30B mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
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Mir30c2 |
microRNA 30c-2 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30C2 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
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Mir30d |
microRNA 30d |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30D mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472
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Mir30e |
microRNA 30e |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR30E mRNA |
CTD |
PMID:25933445 |
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NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
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Mir31 |
microRNA 31 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR31 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 5:103,599,038...103,599,143
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Mir32 |
microRNA 32 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR32 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
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Mir320a |
microRNA 320a |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR320A mRNA |
CTD |
PMID:25933445 |
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NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
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Mir322 |
microRNA 322 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR322 mRNA |
CTD |
PMID:25933445 |
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NCBI chr X:132,806,594...132,806,688
Ensembl chr X:132,806,594...132,806,688
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Mir324 |
microRNA 324 |
affects expression |
EXP |
Bleomycin affects the expression of MIR324 mRNA |
CTD |
PMID:25933445 |
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NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
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Mir326 |
microRNA 326 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR326 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
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Mir328 |
microRNA 328 |
affects expression |
EXP |
Bleomycin affects the expression of MIR328 mRNA |
CTD |
PMID:25933445 |
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NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
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Mir33 |
microRNA 33 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR33 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
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Mir330 |
microRNA 330 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR330 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
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Mir331 |
microRNA 331 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR331 mRNA |
CTD |
PMID:25933445 |
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NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
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Mir340-1 |
microRNA 340-1 |
increases expression |
EXP |
Bleomycin results in increased expression of MIR340-1 mRNA |
CTD |
PMID:25933445 |
|
NCBI chr10:34,393,568...34,393,665
Ensembl chr10:34,393,568...34,393,665
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Mir342 |
microRNA 342 |
decreases expression |
EXP |
Bleomycin results in decreased expression of MIR342 mRNA |
CTD< |