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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:bleomycin
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Accession:CHEBI:22907 term browser browse the term
Definition:A glycopeptide produced by the bacterium Streptomyces verticillus. The term, 'bleomycin' refers to a family of structurally related compounds. When used as an anti-cancer agent, the chemotherapeutical forms are primarily bleomycin A2 and B2.
Synonyms:alt_id: CHEBI:584977
 xref: DrugBank:DB00290;   Wikipedia:Bleomycin


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bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] CTD PMID:20581171 NCBI chr10:94,170,766...94,213,831
Ensembl chr10:94,170,766...94,187,822
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:32,050,734...32,095,860
Ensembl chr  X:32,049,931...32,096,016
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]
CTD PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 PMID:25582705 PMID:25648892 PMID:26520185 PMID:27704718 PMID:28694203 PMID:31302203 PMID:31706003 NCBI chr 1:252,537,614...252,550,394
Ensembl chr 1:252,537,615...252,550,394
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr 6:103,376,557...103,470,497
Ensembl chr 6:103,375,799...103,470,555
JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 1:87,078,012...87,147,347
Ensembl chr 1:87,078,020...87,147,333
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr 6:43,400,525...43,448,280
Ensembl chr 6:43,400,528...43,448,280
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr10:29,392,762...29,450,644
Ensembl chr10:29,392,762...29,450,644
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression
EXP protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705 PMID:25933445 NCBI chr20:4,363,152...4,366,079
Ensembl chr20:4,363,152...4,366,079
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 NCBI chr17:35,907,102...35,958,136
Ensembl chr17:35,907,108...35,958,077
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr11:81,711,269...81,717,594 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 PMID:26520185 NCBI chr 6:137,218,398...137,239,970
Ensembl chr 6:137,218,376...137,236,258
JBrowse link
G Alb albumin increases expression EXP Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr14:19,176,275...19,191,793
Ensembl chr14:19,176,277...19,191,863
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr 1:238,222,689...238,264,381
Ensembl chr 1:238,222,521...238,264,330
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr10:65,586,504...65,590,093
Ensembl chr10:65,586,504...65,590,126
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr 1:254,726,985...254,745,673
Ensembl chr 1:254,726,969...254,735,548
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 2:198,040,573...198,057,005
Ensembl chr 2:198,040,536...198,057,003
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 8:75,687,134...75,723,589
Ensembl chr 8:75,687,100...75,723,594
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr14:14,371,921...14,426,503
Ensembl chr14:14,364,008...14,426,437
JBrowse link
G Anxa4 annexin A4 decreases expression EXP Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 4:118,538,775...118,595,591
Ensembl chr 4:118,538,777...118,595,580
JBrowse link
G Anxa5 annexin A5 increases expression EXP Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 2:123,162,477...123,194,730
Ensembl chr 2:123,162,461...123,193,130
JBrowse link
G Anxa6 annexin A6 decreases expression EXP Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr10:40,320,581...40,375,605
Ensembl chr10:40,320,581...40,375,605
JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:4,254,470...4,281,296
Ensembl chr15:4,254,499...4,281,287
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 4:85,551,503...85,563,683
Ensembl chr 4:85,551,502...85,569,360
JBrowse link
G Areg amphiregulin increases expression ISO Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr14:18,521,921...18,531,179
Ensembl chr14:18,521,930...18,531,179
JBrowse link
G Arg1 arginase 1 increases expression ISO Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein CTD PMID:26345256 PMID:26526764 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr 7:2,504,708...2,511,748
Ensembl chr 7:2,504,695...2,511,749
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Bleomycin results in increased expression of ATPIF1 protein CTD PMID:25933445 NCBI chr 5:150,719,570...150,723,287
Ensembl chr 5:150,719,569...150,723,321
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:2,325,308...2,326,436
Ensembl chr14:2,325,308...2,326,436
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Bleomycin results in decreased expression of ATP5O protein CTD PMID:29733421 NCBI chr11:32,081,606...32,087,918
Ensembl chr11:32,081,574...32,088,002
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Bleomycin results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr11:61,531,386...61,584,634
Ensembl chr11:61,531,416...61,584,634
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr 7:67,341,366...67,345,290
Ensembl chr 7:67,341,080...67,345,308
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr 2:77,586,424...77,632,626
Ensembl chr 2:77,586,424...77,632,628
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
CTD PMID:23656969 PMID:26093215 PMID:32278510 NCBI chr 1:101,451,801...101,457,207
Ensembl chr 1:101,451,802...101,457,207
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
CTD PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:56,834,363...56,840,058
Ensembl chr10:56,834,364...56,839,437
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression
ISO
EXP
BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein
CTD PMID:10815900 PMID:15371238 NCBI chr 8:6,014,014...6,036,668
Ensembl chr 8:6,013,207...6,034,142
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr10:106,856,097...106,864,419
Ensembl chr10:106,856,097...106,864,413
JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr10:63,197,367...63,240,447
Ensembl chr10:63,197,364...63,240,332
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:225,035,956...225,046,137
Ensembl chr 1:225,037,737...225,046,040
JBrowse link
G C1qb complement C1q B chain increases expression ISO Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 5:155,246,444...155,251,995
Ensembl chr 5:155,246,447...155,252,003
JBrowse link
G Cald1 caldesmon 1 increases expression EXP Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 4:62,103,948...62,291,375
Ensembl chr 4:62,220,736...62,291,489
JBrowse link
G Calml3 calmodulin-like 3 decreases expression EXP Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr17:70,070,458...70,073,697
Ensembl chr17:70,072,156...70,073,530
JBrowse link
G Calr calreticulin increases expression EXP Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr19:25,956,771...25,961,666
Ensembl chr19:25,956,771...25,961,666
JBrowse link
G Calu calumenin increases expression EXP Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 4:56,625,611...56,653,112
Ensembl chr 4:56,625,561...56,653,111
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression EXP Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 2:88,185,204...88,227,486
Ensembl chr 2:88,217,188...88,227,479
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 2:88,097,740...88,112,868
Ensembl chr 2:88,097,720...88,113,029
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression EXP Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr10:7,041,510...7,055,107
Ensembl chr10:7,041,510...7,055,101
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
Bleomycin results in increased activity of CASP3 protein
CTD PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 9:65,614,142...65,662,624
Ensembl chr 9:65,614,142...65,662,106
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP
ISO
Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA
Bleomycin results in increased activity of CASP9 protein
CTD PMID:15371238 PMID:22687607 PMID:26800624 NCBI chr 5:160,356,211...160,373,774
Ensembl chr 5:160,355,833...160,373,778
JBrowse link
G Cast calpastatin increases expression EXP Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr 2:1,452,111...1,561,669
Ensembl chr 2:1,452,116...1,561,464
JBrowse link
G Cat catalase increases response to substance
multiple interactions
decreases activity
increases expression
ISO
EXP
CAT protein results in increased susceptibility to Bleomycin
tripterine inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]
CTD PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Cav1 caveolin 1 decreases expression EXP Bleomycin results in decreased expression of CAV1 protein CTD PMID:25933445 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression EXP Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 9:55,244,136...55,256,153
Ensembl chr 9:55,243,255...55,256,340
JBrowse link
G Cckar cholecystokinin A receptor decreases expression EXP Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr14:59,610,939...59,619,786
Ensembl chr14:59,611,434...59,619,783
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases expression
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
Bleomycin results in decreased expression of CCL11 mRNA
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:16314464 PMID:29720568 NCBI chr10:69,434,965...69,439,566
Ensembl chr10:69,434,941...69,439,575
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL12 mRNA
Bleomycin results in decreased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
CTD PMID:28434932 PMID:29720568 NCBI chr10:69,476,866...69,478,416
Ensembl chr10:69,476,775...69,478,462
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256 PMID:29175452 NCBI chr19:10,619,220...10,620,671
Ensembl chr19:10,619,220...10,620,671
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
Bleomycin results in decreased expression of CCL2 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
CTD PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 PMID:26520185 PMID:26526764 PMID:29720568 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL3 mRNA
Bleomycin results in decreased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
CTD PMID:26520185 PMID:29720568 NCBI chr10:70,869,516...70,871,066
Ensembl chr10:70,869,513...70,871,066
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr10:70,870,926...70,886,357
Ensembl chr10:70,884,531...70,886,355
JBrowse link
G Ccl6 chemokine (C-C motif) ligand 6 increases expression ISO Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr10:70,798,118...70,802,750
Ensembl chr10:70,797,124...70,802,782
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr10:69,423,083...69,424,933
Ensembl chr10:69,423,086...69,424,979
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein
CTD PMID:19080365 PMID:26817844 PMID:28434932 NCBI chr 1:21,851,657...21,854,773
Ensembl chr 1:21,851,660...21,854,773
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr10:25,903,925...25,910,298
Ensembl chr10:25,903,911...25,910,325
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression
decreases response to substance
ISO CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
Bleomycin results in increased expression of CCR2 mRNA
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:14609568 PMID:29033951
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 8:133,026,539...133,040,999
Ensembl chr 8:133,029,625...133,040,997
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression ISO Bleomycin affects the expression of CCR5 mRNA CTD PMID:26345256 NCBI chr 8:133,192,398...133,215,599
Ensembl chr 8:133,197,032...133,215,614
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:27,130,172...27,141,881
Ensembl chr11:27,130,172...27,141,881
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 4:14,150,309...14,191,498
Ensembl chr 4:14,001,761...14,249,749
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr11:67,060,305...67,117,990
Ensembl chr11:67,082,193...67,118,795
JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 5:137,260,728...137,264,931
Ensembl chr 5:137,260,739...137,265,015
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein
CTD PMID:28300665 PMID:28694203 NCBI chr19:38,768,467...38,838,395
Ensembl chr19:38,768,467...38,838,395
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 PMID:29720568 NCBI chr20:6,348,422...6,358,864
Ensembl chr20:6,351,458...6,358,864
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
increases response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CEBPB mRNA
CEBPB protein results in increased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:17177178 PMID:21998664 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr19:15,195,514...15,239,827
Ensembl chr19:15,033,108...15,239,821
JBrowse link
G Cfl1 cofilin 1 increases expression EXP Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr 1:220,869,805...220,873,337
Ensembl chr 1:220,869,805...220,873,337
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions
ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein]
CTD PMID:24933654 NCBI chr12:51,845,574...51,878,098
Ensembl chr12:51,845,796...51,877,624
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 2:189,088,570...189,096,785
Ensembl chr 2:189,088,570...189,096,785
JBrowse link
G Ckb creatine kinase B increases expression EXP Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr 6:136,142,956...136,145,838
Ensembl chr 6:136,142,956...136,145,837
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression EXP Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:16,170,585...16,196,691
Ensembl chr  X:16,050,780...16,196,789
JBrowse link
G Cldn4 claudin 4 increases expression ISO Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr12:24,761,210...24,763,008
Ensembl chr12:24,761,210...24,763,005
JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression EXP Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 5:153,568,937...153,625,669
Ensembl chr 5:153,568,745...153,625,869
JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr 9:19,121,676...19,372,673
Ensembl chr 9:19,121,677...19,372,673
JBrowse link
G Cltc clathrin heavy chain decreases expression EXP Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr10:74,014,560...74,070,578
Ensembl chr10:74,014,562...74,070,266
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression
ISO
EXP
[Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
CTD PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 PMID:25933445 PMID:26093215 PMID:26345256 PMID:28300665 PMID:28726637 PMID:29033951 PMID:31302203 NCBI chr10:82,745,801...82,762,790
Ensembl chr10:82,745,801...82,762,789
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of COL1A2 mRNA
Bleomycin results in decreased expression of COL1A2 protein
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
CTD PMID:19147827 PMID:25933445 NCBI chr 4:31,534,225...31,569,152
Ensembl chr 4:31,534,225...31,569,151
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression
multiple interactions
increases expression
EXP
ISO
Bleomycin results in decreased expression of COL3A1 protein
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
CTD PMID:25933445 PMID:26817844 PMID:28726637 NCBI chr 9:52,023,295...52,059,221
Ensembl chr 9:52,023,295...52,059,217
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP Bleomycin results in decreased expression of COL5A1 protein CTD PMID:25933445 NCBI chr 3:6,430,180...6,581,010
Ensembl chr 3:6,430,201...6,578,882
JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr16:20,798,437...20,807,070
Ensembl chr16:20,798,437...20,807,070
JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
ISO tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 2:104,744,249...104,803,034
Ensembl chr 2:104,744,461...104,799,853
JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr 6:137,953,545...137,958,491
Ensembl chr 6:137,953,545...137,958,490
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
decreases expression
ISO Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA
CTD PMID:18684396 PMID:29720568 NCBI chr10:39,602,089...39,604,070
Ensembl chr10:39,602,089...39,604,070
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression EXP Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr10:86,616,785...86,619,160
Ensembl chr10:86,616,785...86,619,157
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr13:52,553,843...52,575,054
Ensembl chr13:52,553,775...52,575,051
JBrowse link
G Ctsa cathepsin A affects expression ISO Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 3:161,298,750...161,304,627
Ensembl chr 3:161,298,962...161,304,625
JBrowse link
G Ctsb cathepsin B affects expression ISO Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr15:46,316,741...46,337,613
Ensembl chr15:46,316,741...46,337,612
JBrowse link
G Ctsh cathepsin H affects expression ISO Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 8:97,439,155...97,458,293
Ensembl chr 8:97,439,161...97,458,287
JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 2:197,655,780...197,679,768
Ensembl chr 2:197,655,786...197,679,458
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
decreases expression
ISO Bleomycin results in increased expression of CXCL10 mRNA
Bleomycin results in decreased expression of CXCL10 mRNA
CTD PMID:26345256 PMID:29720568 NCBI chr14:17,210,733...17,212,930
Ensembl chr14:17,210,733...17,212,930
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 4:149,261,044...149,273,891
Ensembl chr 4:149,261,044...149,273,891
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr14:15,253,146...15,258,221
Ensembl chr14:15,253,125...15,258,207
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion
ISO Bleomycin results in increased expression of CXCL2 protein
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
CTD PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 NCBI chr14:18,731,346...18,733,391
Ensembl chr14:18,731,378...18,733,391
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein] CTD PMID:26600069 NCBI chr14:18,820,168...18,839,659
Ensembl chr14:18,820,168...18,839,595
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr14:17,228,832...17,233,743
Ensembl chr14:17,228,856...17,234,712
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 4:80,331,226...80,333,326
Ensembl chr 4:80,331,227...80,333,326
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression EXP Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr13:36,147,667...36,156,076
Ensembl chr13:36,117,119...36,174,908
JBrowse link
G Des desmin increases expression EXP Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 9:82,556,574...82,564,288
Ensembl chr 9:82,556,573...82,564,294
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 8:55,062,549...55,087,832
Ensembl chr 8:55,062,551...55,087,832
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP
ISO
Bleomycin results in increased expression of DLD protein CTD PMID:25933445 PMID:29733421 NCBI chr 6:50,597,677...50,618,694
Ensembl chr 6:50,597,677...50,618,694
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr 6:133,576,513...133,583,751
Ensembl chr 6:133,552,821...133,583,751
JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 8:21,922,515...21,968,495
Ensembl chr 8:21,922,515...21,968,495
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr19:55,973,447...55,998,830
Ensembl chr19:55,982,740...55,998,208
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 1:87,009,798...87,015,996
Ensembl chr 1:87,009,730...87,016,005
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 8:85,838,594...85,841,816
Ensembl chr 8:85,838,869...85,840,818
JBrowse link
G Egr1 early growth response 1 increases expression
affects expression
multiple interactions
ISO Bleomycin results in increased expression of EGR1 mRNA
Bleomycin affects the expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
CTD PMID:19147827 PMID:26345256 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Egr2 early growth response 2 affects expression ISO Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr20:22,452,170...22,461,018
Ensembl chr20:22,454,463...22,459,025
JBrowse link
G Ehd1 EH-domain containing 1 decreases expression EXP Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr 1:221,644,867...221,667,242
Ensembl chr 1:221,644,867...221,667,239
JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 1:77,847,599...77,865,870
Ensembl chr 1:77,847,600...77,865,870
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr10:56,527,075...56,531,615
Ensembl chr10:56,527,085...56,531,483
JBrowse link
G Eln elastin increases expression ISO Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr12:24,978,478...25,021,864
Ensembl chr12:24,978,483...25,021,863
JBrowse link
G Epx eosinophil peroxidase increases expression EXP Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr10:75,160,690...75,171,774
Ensembl chr10:75,160,690...75,171,774
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 8:33,756,634...33,879,625
Ensembl chr 8:33,816,386...33,879,625
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr11:36,075,709...36,092,495
Ensembl chr11:36,075,709...36,092,495
JBrowse link
G Ezr ezrin decreases expression EXP Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr 1:47,287,872...47,331,412
Ensembl chr 1:47,287,874...47,331,412
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression
EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein
CTD PMID:23656969 NCBI chr 2:25,222,324...25,235,275
Ensembl chr 2:25,222,328...25,235,275
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 2:93,792,666...93,797,267
Ensembl chr 2:93,792,601...93,797,305
JBrowse link
G Faslg Fas ligand increases expression ISO Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr13:79,696,811...79,717,581
Ensembl chr13:79,698,445...79,705,705
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions
EXP Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
CTD PMID:25582705 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:159,112,516...159,172,528
Ensembl chr  X:159,112,880...159,172,524
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of FN1 protein
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]
CTD PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 PMID:31302203 NCBI chr 9:78,900,111...78,969,018
Ensembl chr 9:78,900,103...78,969,078
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of FOS protein CTD PMID:12003776 NCBI chr 6:109,300,433...109,303,299
Ensembl chr 6:109,300,433...109,303,299
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:15,753,175...15,768,648
Ensembl chr  X:15,753,175...15,768,522
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr 6:12,796,383...12,997,817
Ensembl chr 6:12,796,383...12,997,817
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression EXP Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 2:257,425,676...257,452,745
Ensembl chr 2:257,425,679...257,449,568
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions
ISO Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]
CTD PMID:28726637 NCBI chr 7:77,898,329...77,931,034
Ensembl chr 7:77,899,322...77,931,029
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression EXP Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr14:39,154,072...39,230,994
Ensembl chr14:39,154,529...39,231,695
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr10:27,973,694...28,193,072
Ensembl chr10:27,973,681...28,187,565
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr10:27,090,913...27,179,786
Ensembl chr10:27,092,827...27,179,900
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression EXP Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 5:48,374,048...48,411,170
Ensembl chr 5:48,374,096...48,411,170
JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr 1:225,096,558...225,116,384
Ensembl chr 1:225,096,598...225,116,378
JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr16:81,213,364...81,243,824
Ensembl chr16:81,213,364...81,243,757
JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]
CTD PMID:29033951 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr14:20,267,023...20,302,577
Ensembl chr14:20,266,891...20,302,581
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression
ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gda guanine deaminase decreases expression EXP Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr 1:238,982,542...239,057,663
Ensembl chr 1:238,982,392...239,057,732
JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression EXP Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 1:90,063,411...90,091,287
Ensembl chr 1:90,063,411...90,091,287
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 8:117,117,430...117,118,528
Ensembl chr 8:117,117,430...117,118,522
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 2:179,584,302...179,704,629
Ensembl chr 2:179,584,308...179,704,629
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 5:143,500,441...143,715,546
Ensembl chr 5:143,500,441...143,715,546
JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:32,746,259...32,786,266
Ensembl chr  X:32,745,873...32,786,359
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Gsn gelsolin decreases expression EXP Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP Bleomycin results in decreased activity of GSR protein
tripterine inhibits the reaction [Bleomycin results in decreased activity of GSR protein]
CTD PMID:26768587 NCBI chr16:62,197,617...62,239,987
Ensembl chr16:62,197,617...62,241,361
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 2:210,803,869...210,809,461
Ensembl chr 2:210,803,869...210,809,306
JBrowse link
G H1f0 H1 histone family, member 0 affects expression EXP Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr 7:120,260,776...120,262,636 JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression EXP Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr17:43,734,461...43,735,120
Ensembl chr17:43,734,461...43,735,120
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 8:48,665,652...48,666,981
Ensembl chr 8:48,665,652...48,666,981
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 6:27,589,840...27,628,921
Ensembl chr 6:27,589,657...27,629,175
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr10:31,813,819...31,860,934
Ensembl chr10:31,813,814...31,848,379
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Bleomycin affects the expression of HBB protein CTD PMID:25933445 NCBI chr 1:168,971,269...168,972,680
Ensembl chr 1:168,971,274...168,972,725
JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:29,330,302...29,340,185
Ensembl chr18:29,329,764...29,340,403
JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases expression
increases secretion
EXP
ISO
Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]
Bleomycin results in increased expression of HGF mRNA
Bleomycin results in increased secretion of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
CTD PMID:16115399 PMID:22687607 PMID:29408570 NCBI chr 4:15,435,460...15,505,377
Ensembl chr 4:15,433,295...15,505,362
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052
JBrowse link
G Hist1h2bg histone cluster 1, H2bg decreases expression EXP Bleomycin results in decreased expression of HIST1H2BG protein CTD PMID:25933445 NCBI chr17:43,817,316...43,817,717
Ensembl chr17:43,817,378...43,817,720
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
EXP
ISO
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD PMID:25582705 PMID:32278510 NCBI chr12:7,082,529...7,090,246
Ensembl chr16:37,500,017...37,502,237
JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of HMOX1 protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; tripterine inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
CTD PMID:16317386 PMID:26093215 PMID:26768587 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 4:81,237,496...81,241,281
Ensembl chr 4:81,237,496...81,241,282
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression EXP Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 3:62,481,222...62,491,356
Ensembl chr 3:62,481,323...62,487,227
JBrowse link
G Hpx hemopexin increases expression EXP Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 1:170,423,558...170,431,066
Ensembl chr 1:170,423,483...170,431,073
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:135,107,262...135,112,793
Ensembl chr 6:135,107,271...135,112,775
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:27,226,570...27,240,533
Ensembl chr 7:27,226,569...27,240,533
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Bleomycin results in increased expression of HSPA5 protein CTD PMID:25933445 NCBI chr 3:13,838,304...13,842,763
Ensembl chr 3:13,838,304...13,842,762
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr12:23,839,390...23,841,051
Ensembl chr12:23,839,399...23,841,049
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO
Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445 PMID:29733421 NCBI chr 9:61,691,246...61,724,948
Ensembl chr 9:61,692,154...61,694,599
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr11:1,982,113...1,983,513
Ensembl chr11:1,982,113...1,983,513
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A decreases expression EXP Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 4:199,916...209,599
Ensembl chr 4:199,916...209,599
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951 PMID:29720568 NCBI chr 8:22,035,287...22,047,049
Ensembl chr 8:22,035,256...22,047,059
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 1:141,874,354...141,893,674
Ensembl chr 1:141,866,283...141,893,705
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
decreases expression
ISO Bleomycin results in increased expression of IFNG mRNA
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG mRNA
CTD PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 NCBI chr 7:61,337,383...61,341,419
Ensembl chr 7:61,337,381...61,341,419
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Il10 interleukin 10 increases expression ISO Bleomycin results in increased expression of IL10 protein CTD PMID:29175452 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il12b interleukin 12B increases expression ISO Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr10:30,034,447...30,048,774
Ensembl chr10:30,038,709...30,048,085
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression ISO Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 4:98,049,195...98,141,562
Ensembl chr 4:98,052,842...98,141,482
JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions
ISO IL13 gene mutant form results in decreased susceptibility to Bleomycin
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
CTD PMID:15322207 NCBI chr10:38,982,909...38,985,466
Ensembl chr10:38,982,909...38,985,466
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1A protein
CTD PMID:8317554 PMID:29175452 NCBI chr 3:121,824,712...121,836,122
Ensembl chr 3:121,825,412...121,836,086
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
affects expression
increases expression
ISO
EXP
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin affects the expression of IL1B mRNA
IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
CTD PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 PMID:17177178 PMID:19147827 PMID:22687607 PMID:26093215 PMID:26520185 PMID:26526764 PMID:26600069 PMID:27704718 PMID:28300665 PMID:28694203 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il4 interleukin 4 increases expression
affects response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of IL4 mRNA
IL4 protein affects the susceptibility to Bleomycin
IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
IL4 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:11554783 PMID:12574379 PMID:15322207 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of IL6 protein
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
CTD PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 PMID:26209236 PMID:26520185 PMID:28300665 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression EXP Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr10:104,057,739...104,075,776
Ensembl chr10:104,057,697...104,075,777
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of JUN protein CTD PMID:12003776 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
EXP Bleomycin results in decreased expression of KEAP1 protein
tripterine inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]
CTD PMID:26768587 NCBI chr 8:22,250,518...22,259,868
Ensembl chr 8:22,250,518...22,259,779
JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr 9:10,013,795...10,023,670
Ensembl chr 9:10,013,854...10,022,924
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions
ISO Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
CTD PMID:29733421 NCBI chr14:35,072,131...35,149,638
Ensembl chr14:35,072,108...35,149,610
JBrowse link
G Kl Klotho decreases expression ISO Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr12:942,974...987,206
Ensembl chr12:943,006...987,551
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 4:179,482,562...179,515,483
Ensembl chr 4:179,486,105...179,515,558
JBrowse link
G Krt19 keratin 19 decreases expression EXP Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr10:88,055,843...88,060,560
Ensembl chr10:88,055,841...88,060,561
JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression EXP Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr14:70,102,813...70,121,797
Ensembl chr14:70,102,814...70,121,797
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr10:85,744,662...85,785,130
Ensembl chr10:85,744,568...85,785,133
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 3:11,414,189...11,417,534
Ensembl chr 3:11,414,186...11,417,546
JBrowse link
G Lep leptin increases expression ISO Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 4:56,337,695...56,351,818
Ensembl chr 4:56,337,695...56,351,818
JBrowse link
G Lgals3 galectin 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of LGALS3 protein
NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]
CTD PMID:26526764 NCBI chr15:24,153,602...24,165,537
Ensembl chr15:24,141,651...24,165,537
JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr10:71,843,991...71,849,293
Ensembl chr10:71,843,991...71,849,293
JBrowse link
G Lmna lamin A/C increases expression EXP Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 2:187,842,884...187,863,552
Ensembl chr 2:187,842,885...187,863,516
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr 7:60,335,968...60,341,264
Ensembl chr 7:60,335,969...60,341,264
JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr17:9,282,109...9,344,698
Ensembl chr17:9,282,675...9,344,678
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form]
CTD PMID:31302203 NCBI chr19:53,635,449...53,643,970
Ensembl chr19:53,629,779...53,646,058
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr11:88,203,863...88,273,301
Ensembl chr11:88,211,599...88,273,254
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 1:198,192,773...198,198,975
Ensembl chr 1:198,192,773...198,198,975
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression EXP Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr20:42,966,140...42,971,838
Ensembl chr20:42,966,140...42,971,838
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions
EXP
ISO
Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein
CTD PMID:25933445 PMID:29733421 NCBI chr12:23,941,451...23,954,406
Ensembl chr12:23,941,448...23,954,431
JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance ISO MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions
increases phosphorylation
ISO Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein
CTD PMID:22687607 NCBI chr 3:121,235,230...121,340,932
Ensembl chr 3:121,235,119...121,342,444
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr20:13,715,219...13,732,980
Ensembl chr20:13,732,198...13,732,859
JBrowse link
G Mir100 microRNA 100 decreases expression EXP Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 8:45,746,948...45,747,027
Ensembl chr 8:45,746,948...45,747,027
JBrowse link
G Mir101-2 microRNA 101-2 decreases expression EXP
ISO
Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445 PMID:28726637 NCBI chr 1:247,263,723...247,263,819
Ensembl chr 1:247,263,723...247,263,819
JBrowse link
G Mir101a microRNA 101a multiple interactions
decreases expression
ISO
EXP
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
Bleomycin results in decreased expression of MIR101A mRNA
CTD PMID:25933445 PMID:28726637 NCBI chr 5:120,168,437...120,168,511
Ensembl chr 5:120,168,433...120,168,515
JBrowse link
G Mir106b microRNA 106b affects expression EXP Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr12:19,307,752...19,307,833
Ensembl chr12:19,307,752...19,307,833
JBrowse link
G Mir107 microRNA 107 decreases expression EXP Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr 1:253,128,250...253,128,336
Ensembl chr 1:253,128,250...253,128,336
JBrowse link
G Mir10a microRNA 10a decreases expression EXP Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr10:84,165,950...84,166,059
Ensembl chr10:84,165,950...84,166,059
JBrowse link
G Mir10b microRNA 10b decreases expression EXP Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 3:61,647,978...61,648,086
Ensembl chr 3:61,647,978...61,648,086
JBrowse link
G Mir1224 microRNA 1224 increases expression EXP Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr11:83,992,628...83,992,712
Ensembl chr11:83,992,628...83,992,712
JBrowse link
G Mir1249 microRNA 1249 affects expression EXP Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr 7:125,861,192...125,861,311
Ensembl chr 7:125,861,192...125,861,311
JBrowse link
G Mir125a microRNA 125a affects expression EXP Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr 1:59,704,827...59,704,911
Ensembl chr 1:59,704,827...59,704,911
JBrowse link
G Mir126b microRNA 126b decreases expression EXP Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 3:4,042,488...4,042,560 JBrowse link
G Mir130a microRNA 130a decreases expression EXP Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 3:72,141,037...72,141,124
Ensembl chr 3:72,141,037...72,141,124
JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression EXP Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:2,052,478...2,052,564 JBrowse link
G Mir133b microRNA 133b decreases expression EXP Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 9:26,795,649...26,795,732
Ensembl chr 9:26,795,649...26,795,732
JBrowse link
G Mir140 microRNA 140 affects expression EXP Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr19:39,608,951...39,609,049
Ensembl chr19:39,608,951...39,609,049
JBrowse link
G Mir141 microRNA 141 affects expression EXP Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 4:157,236,346...157,236,439
Ensembl chr 4:157,236,346...157,236,439
JBrowse link
G Mir142 microRNA 142 decreases expression
increases expression
EXP Bleomycin results in decreased expression of MIR142 mRNA
Bleomycin results in increased expression of MIR142 mRNA
CTD PMID:25933445 NCBI chr10:75,050,839...75,050,925
Ensembl chr10:75,050,832...75,050,942
JBrowse link
G Mir143 microRNA 143 decreases expression EXP Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:56,971,273...56,971,377
Ensembl chr18:56,971,273...56,971,377
JBrowse link
G Mir144 microRNA 144 decreases expression EXP Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr10:65,291,365...65,291,447
Ensembl chr10:65,291,365...65,291,447
JBrowse link
G Mir145 microRNA 145 decreases expression EXP Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:56,969,907...56,969,994
Ensembl chr18:56,969,907...56,969,994
JBrowse link
G Mir146a microRNA 146a affects expression EXP Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr10:28,962,476...28,962,570
Ensembl chr10:28,962,476...28,962,570
JBrowse link
G Mir146b microRNA 146b increases expression EXP Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr 1:266,089,488...266,089,575
Ensembl chr 1:266,089,488...266,089,575
JBrowse link
G Mir148b microRNA 148b decreases expression EXP Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr 7:144,912,038...144,912,134
Ensembl chr 7:144,912,038...144,912,134
JBrowse link
G Mir150 microRNA 150 affects expression EXP Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 1:101,115,974...101,116,058
Ensembl chr 1:101,115,974...101,116,058
JBrowse link
G Mir151 microRNA 151 decreases expression EXP Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr 7:114,485,547...114,485,643 JBrowse link
G Mir152 microRNA 152 decreases expression EXP Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr10:84,719,319...84,719,403
Ensembl chr10:84,719,319...84,719,403
JBrowse link
G Mir15b microRNA 15b affects expression EXP Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 2:165,605,923...165,606,020
Ensembl chr 2:165,605,923...165,606,020
JBrowse link
G Mir16 microRNA 16 decreases expression EXP Bleomycin results in decreased expression of MIR16 mRNA CTD PMID:25933445 NCBI chr 2:165,606,072...165,606,166
Ensembl chr 2:165,606,072...165,606,166
JBrowse link
G Mir17 microRNA 17 affects expression EXP Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr15:100,179,879...100,179,962
Ensembl chr15:100,179,879...100,179,962
JBrowse link
G Mir181c microRNA 181c decreases expression EXP Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr19:25,290,211...25,290,316
Ensembl chr19:25,290,211...25,290,316
JBrowse link
G Mir181d microRNA 181d decreases expression EXP Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr19:25,290,051...25,290,133
Ensembl chr19:25,290,051...25,290,133
JBrowse link
G Mir183 microRNA 183 affects expression EXP Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 4:57,463,569...57,463,678
Ensembl chr 4:57,463,569...57,463,678
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr11:86,812,702...86,812,781
Ensembl chr11:86,812,702...86,812,781
JBrowse link
G Mir186 microRNA 186 decreases expression EXP Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 2:263,873,759...263,873,844
Ensembl chr 2:263,873,759...263,873,844
JBrowse link
G Mir188 microRNA 188 affects expression EXP Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:16,110,270...16,110,349
Ensembl chr  X:16,110,270...16,110,349
JBrowse link
G Mir18a microRNA 18a increases expression EXP Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr15:100,180,015...100,180,110
Ensembl chr15:100,180,015...100,180,110
JBrowse link
G Mir193 microRNA 193 decreases expression EXP Bleomycin results in decreased expression of MIR193 mRNA CTD PMID:25933445 NCBI chr10:67,065,896...67,065,981 JBrowse link
G Mir195 microRNA 195 decreases expression EXP Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr10:56,845,301...56,845,387
Ensembl chr10:56,845,301...56,845,387
JBrowse link
G Mir199a2 microRNA 199a-2 affects expression EXP Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr13:80,125,487...80,125,596
Ensembl chr13:80,125,487...80,125,596
JBrowse link
G Mir19a microRNA 19a affects expression EXP Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr15:100,180,162...100,180,243
Ensembl chr15:100,180,162...100,180,243
JBrowse link
G Mir200a microRNA 200a decreases expression EXP Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 5:173,489,366...173,489,454 JBrowse link
G Mir200b microRNA 200b decreases expression EXP Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 5:173,490,144...173,490,238
Ensembl chr 5:173,490,144...173,490,238
JBrowse link
G Mir200c microRNA 200c decreases expression EXP Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 4:157,236,786...157,236,854 JBrowse link
G Mir204 microRNA 204 decreases expression EXP Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr 1:240,403,000...240,403,109
Ensembl chr 1:240,403,000...240,403,109
JBrowse link
G Mir20a microRNA 20a affects expression EXP Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr15:100,180,334...100,180,418
Ensembl chr15:100,180,334...100,180,418
JBrowse link
G Mir20b microRNA 20b affects expression EXP Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:140,117,518...140,117,589
Ensembl chr  X:140,117,518...140,117,589
JBrowse link
G Mir21 microRNA 21 increases expression EXP Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr10:73,902,210...73,902,301
Ensembl chr10:73,902,210...73,902,301
JBrowse link
G Mir210 microRNA 210 decreases expression EXP Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 1:214,208,355...214,208,464 JBrowse link
G Mir211 microRNA 211 affects expression EXP Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 1:125,042,119...125,042,224
Ensembl chr 1:125,042,119...125,042,224
JBrowse link
G Mir212 microRNA 212 affects expression EXP Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr10:62,014,702...62,014,812
Ensembl chr10:62,014,702...62,014,812
JBrowse link
G Mir22 microRNA 22 affects expression EXP Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr10:62,299,592...62,299,686
Ensembl chr10:62,299,592...62,299,686
JBrowse link
G Mir221 microRNA 221 decreases expression EXP Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:3,684,480...3,684,588
Ensembl chr  X:3,684,480...3,684,588
JBrowse link
G Mir222 microRNA 222 decreases expression EXP Bleomycin results in decreased expression of MIR222 mRNA CTD PMID:25933445 NCBI chr  X:3,683,919...3,684,021
Ensembl chr  X:3,683,919...3,684,021
JBrowse link
G Mir223 microRNA 223 affects expression EXP Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:65,367,812...65,367,921
Ensembl chr  X:65,367,812...65,367,921
JBrowse link
G Mir23a microRNA 23a decreases expression EXP Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr19:25,318,582...25,318,656
Ensembl chr19:25,318,582...25,318,656
JBrowse link
G Mir23b microRNA 23b decreases expression EXP Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr17:823,222...823,318
Ensembl chr17:823,222...823,318
JBrowse link
G Mir24-2 microRNA 24-2 decreases expression EXP Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr19:25,318,863...25,318,970
Ensembl chr19:25,318,863...25,318,970
JBrowse link
G Mir25 microRNA 25 affects expression EXP Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr12:19,307,340...19,307,423
Ensembl chr12:19,307,340...19,307,423
JBrowse link
G Mir26a microRNA 26a decreases expression EXP Bleomycin results in decreased expression of MIR26A mRNA CTD PMID:25933445 NCBI chr 8:127,714,441...127,714,530
Ensembl chr 8:127,714,441...127,714,530
JBrowse link
G Mir26b microRNA 26b decreases expression EXP Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 9:81,675,275...81,675,359
Ensembl chr 9:81,675,275...81,675,359
JBrowse link
G Mir27a microRNA 27a decreases expression EXP Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr19:25,318,736...25,318,822
Ensembl chr19:25,318,736...25,318,822
JBrowse link
G Mir27b microRNA 27b decreases expression EXP Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr17:823,461...823,557
Ensembl chr17:823,461...823,557
JBrowse link
G Mir28 microRNA 28 decreases expression EXP Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr11:79,380,523...79,380,608
Ensembl chr11:79,380,523...79,380,608
JBrowse link
G Mir290 microRNA 290 increases expression EXP Bleomycin results in increased expression of MIR290 mRNA CTD PMID:25933445 NCBI chr 1:64,538,705...64,538,785
Ensembl chr 1:64,538,705...64,538,785
JBrowse link
G Mir296 microRNA 296 affects expression EXP Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 3:172,357,490...172,357,567
Ensembl chr 3:172,357,490...172,357,567
JBrowse link
G Mir2985 microRNA 2985 affects expression EXP Bleomycin affects the expression of MIR2985 mRNA CTD PMID:25933445 NCBI chr 2:179,591,312...179,591,421
Ensembl chr 2:179,591,312...179,591,421
JBrowse link
G Mir29a microRNA 29a decreases expression EXP Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 4:58,343,931...58,344,018 JBrowse link
G Mir301a microRNA 301a affects expression EXP Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr10:74,417,746...74,417,845
Ensembl chr10:74,417,746...74,417,845
JBrowse link
G Mir30a microRNA 30a decreases expression EXP Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 9:29,542,635...29,542,705
Ensembl chr 9:29,542,635...29,542,705
JBrowse link
G Mir30b microRNA 30b decreases expression EXP Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr 7:109,282,662...109,282,747
Ensembl chr 7:109,282,658...109,282,752
JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression EXP Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 9:29,562,376...29,562,459
Ensembl chr 9:29,562,376...29,562,459
JBrowse link
G Mir30d microRNA 30d decreases expression EXP Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr 7:109,286,463...109,286,544
Ensembl chr 7:109,286,463...109,286,544
JBrowse link
G Mir30e microRNA 30e decreases expression EXP Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 5:139,702,872...139,702,963
Ensembl chr 5:139,702,872...139,702,963
JBrowse link
G Mir31 microRNA 31 decreases expression EXP Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 5:107,206,515...107,206,620 JBrowse link
G Mir32 microRNA 32 increases expression EXP Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 5:73,934,255...73,934,324
Ensembl chr 5:73,934,255...73,934,324
JBrowse link
G Mir320a microRNA 320a decreases expression EXP Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr15:52,134,276...52,134,357
Ensembl chr15:52,134,276...52,134,357
JBrowse link
G Mir322 microRNA 322 decreases expression EXP Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:158,148,161...158,148,255
Ensembl chr  X:158,148,161...158,148,255
JBrowse link
G Mir324 microRNA 324 affects expression EXP Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr10:56,621,126...56,621,208
Ensembl chr10:56,621,124...56,621,212
JBrowse link
G Mir326 microRNA 326 decreases expression EXP Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 1:164,518,401...164,518,495
Ensembl chr 1:164,518,401...164,518,495
JBrowse link
G Mir328 microRNA 328 affects expression EXP Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr19:37,263,199...37,263,282
Ensembl chr19:37,263,199...37,263,282
JBrowse link
G Mir33 microRNA 33 decreases expression EXP Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr 7:123,431,612...123,431,680
Ensembl chr 7:123,431,612...123,431,680
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 1:80,092,681...80,092,777
Ensembl chr 1:80,092,681...80,092,777
JBrowse link
G Mir331 microRNA 331 decreases expression EXP Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr 7:34,881,095...34,881,190
Ensembl chr 7:34,881,095...34,881,190
JBrowse link
G Mir340-1 microRNA mir-340-1 increases expression EXP Bleomycin results in increased expression of MIR340-1 mRNA CTD PMID:25933445 Ensembl chr10:35,558,983...35,559,080
Ensembl chr10:35,558,983...35,559,080
JBrowse link
G Mir342 microRNA 342 decreases expression EXP Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr 6:132,561,169...132,561,267
Ensembl chr 6:132,561,169...132,561,267
JBrowse link
G Mir345 microRNA 345 decreases expression EXP Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr 6:132,748,968...132,749,063
Ensembl chr 6:132,748,968...132,749,063
JBrowse link
G Mir347 microRNA mir-347 decreases expression EXP Bleomycin results in decreased expression of MIR347 mRNA CTD PMID:25933445
G Mir3473 microRNA 3473 increases expression EXP Bleomycin results in increased expression of MIR3473 mRNA CTD PMID:25933445 NCBI chr13:44,719,335...44,719,401
Ensembl chr13:44,719,335...44,719,401
JBrowse link
G Mir34a microRNA 34a affects expression EXP Bleomycin affects the expression of MIR34A mRNA CTD PMID:25933445 NCBI chr 5:167,092,491...167,092,592
Ensembl chr 5:167,092,491...167,092,592
JBrowse link
G Mir34b microRNA 34b decreases expression EXP Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 8:55,492,542...55,492,625
Ensembl chr 8:55,492,542...55,492,625
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 8:55,492,024...55,492,100
Ensembl chr 8:55,492,024...55,492,100
JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Bleomycin results in decreased expression of MIR352 mRNA CTD PMID:25933445
G Mir3545 microRNA 3545 decreases expression EXP Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr 6:136,704,947...136,705,061
Ensembl chr 6:136,704,947...136,705,061
JBrowse link
G Mir3573 microRNA 3573 decreases expression EXP Bleomycin results in decreased expression of MIR3573 mRNA CTD PMID:25933445 NCBI chr  X:68,892,972...68,893,043
Ensembl chr  X:68,892,972...68,893,043
JBrowse link
G Mir3584 microRNA 3584 affects expression EXP Bleomycin affects the expression of MIR3584 mRNA CTD PMID:25933445 NCBI chr 1:271,275,895...271,275,975
Ensembl chr 1:271,275,895...271,275,975
JBrowse link
G Mir361 microRNA 361 decreases expression EXP Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:84,708,911...84,708,980
Ensembl chr  X:84,708,911...84,708,980
JBrowse link
G Mir365b microRNA 365b decreases expression EXP Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr10:67,079,796...67,079,881
Ensembl chr10:67,079,796...67,079,881
JBrowse link
G Mir374b microRNA 374b decreases expression EXP Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:74,443,648...74,443,715
Ensembl chr  X:74,443,648...74,443,715
JBrowse link
G Mir375 microRNA 375 decreases expression EXP Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 9:82,161,716...82,161,790
Ensembl chr 9:82,161,716...82,161,790
JBrowse link
G Mir378 microRNA 378 decreases expression EXP Bleomycin results in decreased expression of MIR378 mRNA CTD PMID:25933445 NCBI chr18:56,726,150...56,726,214 JBrowse link
G Mir409 microRNA 409 affects expression EXP Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr 6:133,893,419...133,893,495 JBrowse link
G Mir423 microRNA 423 decreases expression EXP Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr10:63,098,366...63,098,444
Ensembl chr10:63,098,360...63,098,453
JBrowse link
G Mir425 microRNA 425 affects expression EXP Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 8:117,354,821...117,354,903
Ensembl chr 8:117,354,821...117,354,903
JBrowse link
G Mir429 microRNA 429 decreases expression EXP Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 5:173,488,331...173,488,415
Ensembl chr 5:173,488,331...173,488,415
JBrowse link
G Mir449a microRNA 449a affects expression EXP Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr 2:44,897,601...44,897,691
Ensembl chr 2:44,897,601...44,897,691
JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:158,153,377...158,153,467
Ensembl chr  X:158,153,377...158,153,467
JBrowse link
G Mir451a microRNA 451a decreases expression EXP Bleomycin results in decreased expression of MIR451A mRNA CTD PMID:25933445 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Mir494 microRNA 494 decreases expression EXP Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr 6:133,864,370...133,864,452
Ensembl chr 6:133,864,369...133,864,453
JBrowse link
G Mir497 microRNA 497 decreases expression EXP Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr10:56,844,977...56,845,045
Ensembl chr10:56,844,977...56,845,045
JBrowse link
G Mir500 microRNA 500 affects expression EXP Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:16,121,332...16,121,411
Ensembl chr  X:16,121,322...16,121,413
JBrowse link
G Mir503 microRNA 503 decreases expression EXP Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:158,148,476...158,148,546
Ensembl chr  X:158,148,476...158,148,546
JBrowse link
G Mir532 microRNA 532 affects expression EXP Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:16,109,870...16,109,948
Ensembl chr  X:16,109,870...16,109,948
JBrowse link
G Mir542 microRNA 542 decreases expression EXP Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:158,152,146...158,152,224
Ensembl chr  X:158,152,146...158,152,224
JBrowse link
G Mir6215 microRNA 6215 decreases expression EXP Bleomycin results in decreased expression of MIR6215 mRNA CTD PMID:25933445 NCBI chr 5:158,060,994...158,061,060
Ensembl chr 5:158,060,994...158,061,060
JBrowse link
G Mir6216 microRNA 6216 decreases expression EXP Bleomycin results in decreased expression of MIR6216 mRNA CTD PMID:25933445 NCBI chr 3:46,361,908...46,361,985
Ensembl chr 3:46,361,908...46,361,985
JBrowse link
G Mir6328 microRNA 6328 affects expression EXP Bleomycin affects the expression of MIR6328 mRNA CTD PMID:25933445 NCBI chr20:3,394,813...3,394,909
Ensembl chr20:3,394,813...3,394,909
JBrowse link
G Mir652 microRNA 652 affects expression EXP Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:114,002,534...114,002,614
Ensembl chr  X:114,002,534...114,002,614
JBrowse link
G Mir93 microRNA 93 affects expression EXP Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr12:19,307,543...19,307,629
Ensembl chr12:19,307,543...19,307,629
JBrowse link
G Mir96 microRNA 96 affects expression EXP Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 4:57,463,366...57,463,471
Ensembl chr 4:57,463,366...57,463,471
JBrowse link
G Mir98 microRNA 98 decreases expression EXP Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:21,583,875...21,583,982
Ensembl chr  X:21,583,875...21,583,982
JBrowse link
G Mir99a microRNA 99a decreases expression EXP Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr11:16,052,153...16,052,233
Ensembl chr11:16,052,153...16,052,233
JBrowse link
G Mir99b microRNA 99b decreases expression EXP Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr 1:59,704,216...59,704,285
Ensembl chr 1:59,704,216...59,704,285
JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr 7:126,590,627...126,590,711
Ensembl chr 7:126,590,627...126,590,711
JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr17:16,419,980...16,420,077
Ensembl chr17:16,419,980...16,420,077
JBrowse link
G Mirlet7i microRNA let-7i decreases expression EXP Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr 7:66,802,731...66,802,815
Ensembl chr 7:66,802,732...66,802,821
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:5,703,206...5,723,593
Ensembl chr 8:5,703,206...5,723,591
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; tripterine inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
CTD PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 NCBI chr19:15,542,771...15,570,589
Ensembl chr19:15,542,765...15,570,611
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 8:5,676,608...5,698,579
Ensembl chr 8:5,676,665...5,698,579
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; tripterine inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
CTD PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 NCBI chr 3:161,413,410...161,421,473
Ensembl chr 3:161,413,298...161,421,520
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity
ISO
EXP
pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Bleomycin results in increased expression of MPO protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein]
CTD PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 NCBI chr10:75,087,892...75,098,260
Ensembl chr10:75,087,892...75,098,260
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr17:81,352,700...81,433,743
Ensembl chr17:81,352,700...81,433,743
JBrowse link
G Msn moesin decreases expression EXP Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:65,226,834...65,294,192
Ensembl chr  X:65,226,748...65,295,810
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]
CTD PMID:18684396 PMID:26093215 NCBI chr 1:214,725,482...214,756,653 JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 4:154,676,382...154,729,288
Ensembl chr 4:154,391,647...154,729,310
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance ISO MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Myh11 myosin heavy chain 11 decreases expression EXP Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr10:764,421...859,184
Ensembl chr10:764,421...859,184
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr15:33,605,653...33,629,730
Ensembl chr15:33,605,654...33,629,699
JBrowse link
G Myl12b myosin light chain 12B increases expression EXP Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr 9:119,307,168...119,321,500
Ensembl chr 9:119,307,176...119,321,500
JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr10:92,628,356...92,638,100
Ensembl chr10:92,628,356...92,638,100
JBrowse link
G Myl6l myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like increases expression EXP Bleomycin results in increased expression of MYL6L protein CTD PMID:25933445
G Myo1c myosin 1C decreases expression EXP Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr10:63,803,311...63,819,614
Ensembl chr10:63,803,309...63,819,614
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr 7:54,213,305...54,237,880
Ensembl chr 7:54,213,319...54,236,625
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions
increases expression
ISO MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr 3:165,241,750...165,374,644
Ensembl chr 3:165,245,238...165,360,292
JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 affects localization
multiple interactions
decreases expression
increases expression
increases phosphorylation
ISO
EXP
Bleomycin affects the localization of NFE2L2 protein
Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; tripterine inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]
Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein]
CTD PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
multiple interactions
increases expression
ISO
EXP
Bleomycin results in increased activity of NFKB1 protein
NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
CTD PMID:12003776 PMID:26093215 PMID:26526764 NCBI chr 2:240,773,520...240,890,053
Ensembl chr 2:240,773,456...240,866,689
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr 6:76,267,227...76,270,457
Ensembl chr 6:76,267,228...76,270,457
JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:45,462,345...45,473,107
Ensembl chr11:45,462,345...45,473,104
JBrowse link
G Nmbr neuromedin B receptor decreases expression EXP Bleomycin results in decreased expression of NMBR mRNA CTD PMID:15808516 NCBI chr 1:8,933,744...8,945,850
Ensembl chr 1:8,933,831...8,944,987
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Bleomycin results in increased expression of NME2 protein CTD PMID:25933445 NCBI chr10:81,648,216...81,653,717
Ensembl chr10:81,648,216...81,653,717
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of NOS2 protein
Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
CTD PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 PMID:27704718 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP Bleomycin results in increased expression of NPM1 protein CTD PMID:25933445 NCBI chr10:18,080,949...18,091,062
Ensembl chr10:18,080,950...18,090,950
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity
multiple interactions
EXP Bleomycin results in decreased activity of NQO1 protein
tripterine inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein]
CTD PMID:26768587 NCBI chr19:38,422,210...38,437,103
Ensembl chr19:38,422,164...38,437,180
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Bleomycin results in decreased expression of NR3C1 mRNA CTD PMID:15808516 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Bleomycin results in decreased expression of NR3C2 mRNA CTD PMID:15808516 NCBI chr19:34,408,275...34,761,003
Ensembl chr19:34,448,289...34,752,695
JBrowse link
G Nucb2 nucleobindin 2 increases expression EXP Bleomycin results in increased expression of NUCB2 protein CTD PMID:25933445 NCBI chr 1:185,106,773...185,143,278
Ensembl chr 1:185,104,656...185,143,272
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:204,562,289...204,582,070
Ensembl chr 1:204,562,289...204,582,070
JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression EXP Bleomycin results in increased expression of OSTF1 protein CTD PMID:25933445 NCBI chr 1:234,749,568...234,796,739
Ensembl chr 1:234,749,568...234,796,739
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP Bleomycin results in increased expression of P4HB protein CTD PMID:25933445 NCBI chr10:109,736,459...109,748,070
Ensembl chr10:109,736,458...109,747,987
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression EXP Bleomycin results in increased expression of PABPC1 protein CTD PMID:25933445 NCBI chr 7:75,409,581...75,421,874
Ensembl chr 7:75,409,581...75,422,268
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
increases cleavage
ISO
EXP
Bleomycin results in increased expression of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]
Bleomycin results in increased cleavage of PARP1 protein
CTD PMID:15371238 PMID:16317386 PMID:32278510 NCBI chr13:98,857,255...98,889,444
Ensembl chr13:98,857,177...98,889,716
JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:144,077,901...144,103,723
Ensembl chr 7:144,078,496...144,101,893
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:113,376,983...113,400,707
Ensembl chr 3:113,376,983...113,400,707
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression EXP Bleomycin results in increased expression of PDLIM1 protein CTD PMID:25933445 NCBI chr 1:259,308,326...259,357,006
Ensembl chr 1:259,308,296...259,357,056
JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression EXP Bleomycin results in increased expression of PDLIM5 protein CTD PMID:25933445 NCBI chr 2:247,815,214...247,989,198
Ensembl chr 2:247,818,243...247,988,462
JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
ISO Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein
Bleomycin results in decreased expression of PLAU protein
CTD PMID:25648892 NCBI chr15:3,644,296...3,650,765
Ensembl chr15:3,644,769...3,650,819
JBrowse link
G Pml PML nuclear body scaffold multiple interactions
increases expression
ISO arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 NCBI chr 8:63,002,515...63,034,310
Ensembl chr 8:63,004,870...63,034,226
JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression EXP Bleomycin results in decreased expression of PNP protein CTD PMID:25933445 NCBI chr15:27,875,883...27,883,566
Ensembl chr15:27,875,911...27,883,350
JBrowse link
G Podxl podocalyxin-like decreases expression EXP Bleomycin results in decreased expression of PODXL protein CTD PMID:25933445 NCBI chr 4:58,829,049...58,893,353
Ensembl chr 4:58,829,060...58,893,170
JBrowse link
G Polb DNA polymerase beta decreases response to substance ISO POLB results in decreased susceptibility to Bleomycin CTD PMID:21251944 NCBI chr16:74,237,001...74,260,272
Ensembl chr16:74,237,001...74,260,271
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases response to substance
ISO PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]
PPARA protein results in decreased susceptibility to Bleomycin
CTD PMID:16317386 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions
ISO Bleomycin results in decreased expression of PPARG mRNA
Berberine inhibits the reaction [Bleomycin binds to PPARG protein]
rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]
CTD PMID:19147827 PMID:29408570 NCBI chr 4:147,274,055...147,399,383
Ensembl chr 4:147,274,107...147,399,380
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Bleomycin results in increased expression of PPIA protein CTD PMID:25933445 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression EXP Bleomycin results in decreased expression of PRDX2 protein CTD PMID:25933445 NCBI chr19:26,084,816...26,090,095
Ensembl chr19:26,084,903...26,090,094
JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 NCBI chr13:79,077,567...79,088,113
Ensembl chr13:79,077,033...79,088,127
JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein decreases expression EXP Bleomycin results in decreased expression of PRELP protein CTD PMID:25933445 NCBI chr13:50,749,526...50,773,934
Ensembl chr13:50,749,514...50,761,355
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 1:213,636,159...213,648,499
Ensembl chr 1:213,636,093...213,648,488
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression EXP Bleomycin results in increased expression of PSME1 protein CTD PMID:25933445 NCBI chr15:34,256,071...34,258,947
Ensembl chr15:34,256,071...34,258,947
JBrowse link
G Psme2 proteasome activator subunit 2 decreases expression EXP Bleomycin results in decreased expression of PSME2 protein CTD PMID:25933445 NCBI chr15:34,265,552...34,269,851
Ensembl chr15:34,265,557...34,269,851
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP Bleomycin results in increased expression of PTBP1 protein CTD PMID:25933445 NCBI chr 7:12,663,965...12,673,723
Ensembl chr 7:12,663,965...12,673,718
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression
ISO ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein]
Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein
CTD PMID:29408570 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Ptgdr prostaglandin D2 receptor increases expression ISO Bleomycin results in increased expression of PTGDR mRNA CTD PMID:20719937 NCBI chr15:19,195,606...19,196,508 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA]
CTD PMID:26526764 PMID:27704718 NCBI chr13:67,351,230...67,356,920
Ensembl chr13:67,351,087...67,359,335
JBrowse link
G Ptms parathymosin increases expression EXP Bleomycin results in increased expression of PTMS protein CTD PMID:25933445 NCBI chr 4:157,435,371...157,439,507
Ensembl chr 4:157,435,373...157,439,507
JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAB1B protein CTD PMID:25933445 NCBI chr 1:220,483,529...220,491,469
Ensembl chr 1:220,480,834...220,491,469
JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Bleomycin results in increased expression of RALB protein CTD PMID:25933445 NCBI chr13:35,494,716...35,531,503
Ensembl chr13:35,494,721...35,511,020
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAP1B protein CTD PMID:25933445 NCBI chr 7:60,850,406...60,878,226
Ensembl chr 7:60,853,930...60,860,990
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
increases expression
ISO
EXP
Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Bleomycin results in decreased expression of RELA mRNA
Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein]
CTD PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:29720568 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO Bleomycin results in decreased expression of RELB mRNA CTD PMID:29720568 NCBI chr 1:80,517,081...80,545,019
Ensembl chr 1:80,517,411...80,544,825
JBrowse link
G RGD1562690 similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M) decreases expression EXP Bleomycin results in decreased expression of RGD1562690 protein CTD PMID:25933445 NCBI chr 8:33,075,109...33,076,725
Ensembl chr 8:33,075,211...33,076,206
JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase increases expression EXP Bleomycin results in increased expression of PDXK protein CTD PMID:25933445 NCBI chr20:10,883,952...10,912,870
Ensembl chr20:10,889,573...10,912,769
JBrowse link
G Rpl12 ribosomal protein L12 increases expression EXP Bleomycin results in increased expression of RPL12 protein CTD PMID:25933445 NCBI chr 3:12,009,578...12,011,952
Ensembl chr 3:12,009,578...12,011,666
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP Bleomycin results in increased expression of RPL13 protein CTD PMID:25933445 NCBI chr19:55,917,489...55,920,040
Ensembl chr19:55,917,736...55,919,996
JBrowse link
G Rpl4 ribosomal protein L4 increases expression EXP Bleomycin results in increased expression of RPL4 protein CTD PMID:25933445 NCBI chr 8:69,121,682...69,126,805
Ensembl chr 8:69,121,682...69,126,805
JBrowse link
G Rpl5 ribosomal protein L5 increases expression EXP Bleomycin results in increased expression of RPL5 protein CTD PMID:25933445 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G Rpl6 ribosomal protein L6 affects expression EXP Bleomycin affects the expression of RPL6 protein CTD PMID:25933445 NCBI chr12:40,877,578...40,882,032
Ensembl chr12:40,877,613...40,881,124
JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Bleomycin results in increased expression of RPS3A1 protein CTD PMID:25933445 NCBI chr 2:185,440,477...185,444,846
Ensembl chr 2:185,440,291...185,444,897
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Bleomycin results in increased expression of S100A11 protein CTD PMID:25933445 NCBI chr 2:193,863,185...193,868,646
Ensembl chr 2:193,866,951...193,868,502
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression
multiple interactions
EXP Bleomycin results in increased expression of S100A4 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein]
CTD PMID:25933445 PMID:31706003 NCBI chr 2:189,997,278...189,999,587
Ensembl chr 2:189,997,129...189,999,604
JBrowse link
G S100a6 S100 calcium binding protein A6 affects expression EXP Bleomycin affects the expression of S100A6 protein CTD PMID:25933445 NCBI chr 2:190,007,013...190,008,512
Ensembl chr 2:190,007,216...190,008,511
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Bleomycin results in increased expression of S100A8 protein CTD PMID:25933445 NCBI chr 2:190,073,239...190,074,333
Ensembl chr 2:190,073,815...190,074,354
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein CTD PMID:29033951 NCBI chr 2:218,654,406...218,658,761
Ensembl chr 2:218,654,554...218,658,761
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions
increases expression
ISO S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] CTD PMID:29033951 NCBI chr17:13,799,383...13,812,877
Ensembl chr17:13,799,383...13,812,704
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 multiple interactions
affects response to substance
ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] CTD PMID:29033951 NCBI chr 8:22,268,635...22,273,708
Ensembl chr 8:22,268,657...22,270,647
JBrowse link
G Scarna15 small Cajal body-specific RNA 15 affects expression EXP Bleomycin affects the expression of SCARNA15 mRNA CTD PMID:25933445 NCBI chr 1:143,360,224...143,360,287
Ensembl chr 1:143,360,224...143,360,287
JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Bleomycin results in decreased expression of SCGB1A1 protein CTD PMID:25933445 NCBI chr 1:225,279,698...225,283,246
Ensembl chr 1:225,279,676...225,283,326
JBrowse link
G Scp2 sterol carrier protein 2 increases expression EXP Bleomycin results in increased expression of SCP2 protein CTD PMID:25933445 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression EXP Bleomycin results in increased expression of SCPEP1 protein CTD PMID:25933445 NCBI chr10:76,230,371...76,263,866
Ensembl chr10:76,230,373...76,263,866
JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression EXP Bleomycin results in decreased expression of SEC14L3 protein CTD PMID:25933445 NCBI chr14:84,306,466...84,317,241
Ensembl chr14:84,274,550...84,319,449
JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP Bleomycin results in decreased expression of SELENBP1 protein CTD PMID:25933445 NCBI chr 2:196,105,592...196,146,474
Ensembl chr 2:196,105,569...196,113,149
JBrowse link
G Serpine1 serpin family E member 1 increases expression ISO Bleomycin results in increased expression of SERPINE1 protein CTD PMID:29175452 NCBI chr12:22,641,104...22,651,482
Ensembl chr12:22,641,104...22,651,482
JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions
increases expression
EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] CTD PMID:23656969 PMID:25933445 NCBI chr 1:164,301,010...164,308,306
Ensembl chr 1:164,301,010...164,308,317
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Bleomycin results in increased expression of SFRP1 mRNA CTD PMID:26345256 NCBI chr16:73,372,007...73,410,777
Ensembl chr16:73,372,007...73,410,777
JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions
increases expression
decreases expression
ISO
EXP
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]
Bleomycin results in increased expression of SFTPA1 protein
Bleomycin results in decreased expression of SFTPA1 mRNA
CTD PMID:14617519 PMID:15782499 PMID:25933445 NCBI chr16:18,716,019...18,719,404
Ensembl chr16:18,716,019...18,719,403
JBrowse link
G Sftpb surfactant protein B decreases expression EXP Bleomycin results in decreased expression of SFTPB mRNA CTD PMID:15782499 NCBI chr 4:100,166,855...100,175,941
Ensembl chr 4:100,166,863...100,175,938
JBrowse link
G Sftpd surfactant protein D increases expression
multiple interactions
increases metabolic processing
EXP
ISO
Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein
Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein]
CTD PMID:11880309 PMID:25933445 PMID:26526764 NCBI chr16:18,753,535...18,766,100
Ensembl chr16:18,745,458...18,766,174
JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions
ISO Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein
resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein]
CTD PMID:25707573 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Bleomycin results in increased expression of SLC12A1 mRNA CTD PMID:15808516 NCBI chr 3:117,421,531...117,498,372
Ensembl chr 3:117,421,604...117,498,367
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Bleomycin results in increased expression of SLC1A2 mRNA CTD PMID:15808516 NCBI chr 3:92,518,679...92,665,731
Ensembl chr 3:92,640,752...92,665,644
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression EXP Bleomycin results in decreased expression of SLC25A4 protein CTD PMID:25933445 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases expression EXP Bleomycin results in decreased expression of SLC25A5 protein CTD PMID:25933445 NCBI chr  X:123,404,570...123,407,637
Ensembl chr  X:123,404,518...123,407,645
JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression EXP Bleomycin results in increased expression of SLC6A12 mRNA CTD PMID:15808516 NCBI chr 4:153,921,199...153,941,333
Ensembl chr 4:153,921,115...153,941,391
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 increases expression EXP Bleomycin results in increased expression of SLC9A3R1 protein CTD PMID:25933445 NCBI chr10:103,713,045...103,730,145
Ensembl chr10:103,713,045...103,730,145
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 decreases expression EXP Bleomycin results in decreased expression of SLC9A3R2 protein CTD PMID:25933445 NCBI chr10:14,003,330...14,015,066
Ensembl chr10:14,003,320...14,013,870
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:164,623,313...164,671,612
Ensembl chr 1:164,623,599...164,671,577
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Bleomycin results in increased expression of SLPI protein CTD PMID:26345256 NCBI chr 3:160,799,979...160,802,228
Ensembl chr 3:160,799,981...160,802,433
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
ISO Bleomycin results in increased phosphorylation of SMAD2 protein
camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]
CTD PMID:26599507 NCBI chr18:72,550,107...72,612,078
Ensembl chr18:72,550,219...72,612,078
JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases phosphorylation
increases expression
EXP
ISO
Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA]
Bleomycin results in increased phosphorylation of SMAD3 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]
CTD PMID:26093215 PMID:27704718 NCBI chr 8:68,569,530...68,678,349
Ensembl chr 8:68,569,530...68,678,349
JBrowse link
G Smad7 SMAD family member 7 decreases expression
multiple interactions
increases expression
EXP
ISO
Bleomycin results in decreased expression of SMAD7 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA]
CTD PMID:26093215 PMID:29033951 NCBI chr18:71,395,830...71,424,164
Ensembl chr18:71,395,830...71,424,157
JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases phosphorylation ISO Bleomycin results in increased phosphorylation of SMC1A protein CTD PMID:24933654 NCBI chr  X:21,710,976...21,755,708
Ensembl chr  X:21,711,019...21,755,525
JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression EXP Bleomycin results in decreased expression of SNORA58 mRNA CTD PMID:25933445 NCBI chr 6:111,468,732...111,468,807
Ensembl chr 6:111,468,732...111,468,807
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Bleomycin results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:4,956,795...4,958,472
Ensembl chr10:4,957,326...4,958,461
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of SOD1 protein
Bleomycin results in decreased expression of SOD1 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]
CTD PMID:8317554 PMID:25933445 NCBI chr11:30,363,282...30,368,858
Ensembl chr11:30,363,280...30,368,862
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases activity
ISO
EXP
Bleomycin results in increased expression of SOD2 protein
tripterine inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein]
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
CTD PMID:8317554 PMID:26768587 NCBI chr 1:47,914,757...47,921,587
Ensembl chr 1:47,914,759...47,921,587
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases response to substance ISO SPARC protein results in increased susceptibility to Bleomycin CTD PMID:19446018 NCBI chr10:40,742,390...40,764,232
Ensembl chr10:40,742,400...40,764,185
JBrowse link
G Sparcl1 SPARC like 1 decreases expression EXP Bleomycin results in decreased expression of SPARCL1 protein CTD PMID:25933445 NCBI chr14:6,994,261...7,025,309
Ensembl chr14:6,994,190...7,025,308
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 PMID:29175452 NCBI chr14:6,673,686...6,679,965
Ensembl chr14:6,673,686...6,679,901
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP Bleomycin results in decreased expression of SPTAN1 protein CTD PMID:25933445 NCBI chr 3:8,534,437...8,599,259
Ensembl chr 3:8,534,440...8,599,260
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Bleomycin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP Bleomycin results in decreased expression of SSTR1 mRNA CTD PMID:15808516 NCBI chr 6:79,252,914...79,258,611
Ensembl chr 6:79,254,339...79,258,611
JBrowse link
G Sstr2 somatostatin receptor 2 decreases expression EXP Bleomycin results in decreased expression of SSTR2 mRNA CTD PMID:15808516 NCBI chr10:102,136,283...102,143,449
Ensembl chr10:102,136,283...102,143,434
JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression EXP Bleomycin results in decreased expression of SSTR3 mRNA CTD PMID:15808516 NCBI chr 7:119,760,881...119,768,082
Ensembl chr 7:119,760,888...119,768,082
JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ST14 protein CTD PMID:26599507 NCBI chr 8:32,240,113...32,280,813
Ensembl chr 8:32,240,133...32,280,869
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
decreases response to substance
ISO STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
STAT6 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:15322207 NCBI chr 7:70,946,228...70,963,542
Ensembl chr 7:70,946,228...70,964,484
JBrowse link
G Stk11 serine/threonine kinase 11 increases expression
multiple interactions
ISO Bleomycin results in increased expression of STK11 protein
Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein]
CTD PMID:31302203 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Stmn1 stathmin 1 increases expression EXP Bleomycin results in increased expression of STMN1 protein CTD PMID:25933445 NCBI chr 5:152,680,412...152,686,807
Ensembl chr 5:152,680,407...152,686,806
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b increases expression EXP Bleomycin results in increased expression of SV2B mRNA CTD PMID:15808516 NCBI chr 1:136,664,199...136,842,247
Ensembl chr 1:136,664,204...136,842,247
JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression EXP Bleomycin results in decreased expression of TACR2 mRNA CTD PMID:15808516 NCBI chr20:31,892,515...31,905,153
Ensembl chr20:31,892,515...31,905,153
JBrowse link
G Tagln transgelin increases expression EXP Bleomycin results in increased expression of TAGLN protein CTD PMID:25933445 NCBI chr 8:50,222,895...50,228,369
Ensembl chr 8:50,222,896...50,231,357
JBrowse link
G Tagln2 transgelin 2 increases expression EXP Bleomycin results in increased expression of TAGLN2 protein CTD PMID:25933445 NCBI chr13:90,807,196...90,814,119
Ensembl chr13:90,807,199...90,814,119
JBrowse link
G Taldo1 transaldolase 1 decreases expression EXP Bleomycin results in decreased expression of TALDO1 protein CTD PMID:25933445 NCBI chr 1:214,375,555...214,385,886
Ensembl chr 1:214,375,515...214,385,885
JBrowse link
G Tbx21 T-box transcription factor 21 increases expression ISO Bleomycin results in increased expression of TBX21 mRNA CTD PMID:29033951 NCBI chr10:85,032,799...85,049,331
Ensembl chr10:85,032,799...85,049,331
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 NCBI chr 1:32,250,876...32,275,330
Ensembl chr 1:32,251,714...32,272,476
JBrowse link
G Tf transferrin increases expression EXP Bleomycin results in increased expression of TF protein CTD PMID:25933445 NCBI chr 8:111,694,570...111,721,275
Ensembl chr 8:111,673,547...111,721,333
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
increases secretion
ISO
EXP
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein
Bleomycin results in increased secretion of TGFB1 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
CTD PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 PMID:17177178 PMID:17434272 PMID:19080365 PMID:19112509 PMID:19147827 PMID:20581171 PMID:22687607 PMID:23523906 PMID:26093215 PMID:26209236 PMID:26520185 PMID:26526764 PMID:26599507 PMID:27704718 PMID:28300665 PMID:28434932 PMID:28694203 PMID:29033951 PMID:29720568 PMID:31706003 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression EXP Bleomycin results in decreased expression of TGFB1I1 protein CTD PMID:25933445 NCBI chr 1:199,664,039...199,670,970
Ensembl chr 1:199,664,173...199,670,961
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] CTD PMID:28434932 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of TGFB3 mRNA
CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]
CTD PMID:28434932 NCBI chr 6:109,913,757...109,936,217
Ensembl chr 6:109,913,757...109,935,533
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression
ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
CTD PMID:28434932 PMID:28726637 NCBI chr 5:63,056,071...63,119,635
Ensembl chr 5:63,050,758...63,119,635
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] CTD PMID:28434932 NCBI chr 8:124,310,288...124,399,345
Ensembl chr 8:124,312,754...124,399,494
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Bleomycin results in increased expression of THBS1 mRNA CTD PMID:29720568 NCBI chr 3:109,862,120...109,873,466
Ensembl chr 3:109,862,117...109,873,466
JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression ISO Bleomycin results in decreased expression of THOP1 protein CTD PMID:29733421 NCBI chr 7:11,501,145...11,513,576
Ensembl chr 7:11,501,146...11,513,581
JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Bleomycin results in decreased expression of THRB mRNA CTD PMID:15808516 NCBI chr15:8,890,578...9,239,815
Ensembl chr15:8,890,578...9,086,282
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein
Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]
CTD PMID:26345256 PMID:28300665 NCBI chr  X:1,364,771...1,369,451
Ensembl chr  X:1,364,786...1,369,384
JBrowse link
G Tlr1 toll-like receptor 1 decreases expression ISO Bleomycin results in decreased expression of TLR1 mRNA CTD PMID:29720568 NCBI chr14:45,062,662...45,065,014
Ensembl chr14:45,062,662...45,081,991
JBrowse link
G Tnc tenascin C increases expression ISO Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein CTD PMID:26345256 NCBI chr 5:79,789,686...79,874,555
Ensembl chr 5:79,789,671...79,874,671
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
increases secretion
ISO
EXP
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of TNF mRNA
Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein
Bleomycin results in increased secretion of TNF protein
Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tripterine inhibits the reaction [Bleomycin results in increased expression of TNF protein]
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein]
CTD PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 PMID:14617519 PMID:15541506 PMID:16317386 PMID:17035056 PMID:17118201 PMID:17177178 PMID:19080365 PMID:19362168 PMID:22687607 PMID:23523906 PMID:26093215 PMID:26520185 PMID:26600069 PMID:26768587 PMID:27704718 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases response to substance ISO TNFRSF1A results in increased susceptibility to Bleomycin CTD PMID:12003776 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression
increases response to substance
EXP
ISO
Bleomycin results in increased expression of TNFRSF1B protein
TNFRSF1B results in increased susceptibility to Bleomycin
CTD PMID:12003776 PMID:15371238 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Bleomycin results in decreased expression of TNFSF11 mRNA CTD PMID:29720568 NCBI chr15:60,482,527...60,512,704
Ensembl chr15:60,482,527...60,512,704
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
increases phosphorylation
increases response to substance
ISO Bleomycin results in increased expression of TRP53 protein
Bleomycin results in increased expression of TP53 mRNA
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]
TP53 protein results in increased susceptibility to Bleomycin
CTD PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Bleomycin results in increased expression of TPM1 protein CTD PMID:25933445 NCBI chr 8:72,814,737...72,841,496
Ensembl chr 8:72,814,740...72,842,228
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Bleomycin results in increased expression of TPM3 protein CTD PMID:25933445 NCBI chr 2:189,423,534...189,451,340
Ensembl chr 2:189,423,559...189,451,029
JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression EXP Bleomycin results in decreased expression of TPPP3 protein CTD PMID:25933445 NCBI chr19:37,424,323...37,428,075
Ensembl chr19:37,424,324...37,427,989
JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression EXP Bleomycin results in decreased expression of TRAF2 protein CTD PMID:15371238 NCBI chr 3:2,746,061...2,770,690
Ensembl chr 3:2,746,075...2,770,620
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] CTD PMID:26520185 NCBI chr20:44,679,861...44,722,874
Ensembl chr20:44,680,449...44,722,872
JBrowse link
G Trim28 tripartite motif-containing 28 increases phosphorylation ISO Bleomycin results in increased phosphorylation of TRIM28 protein CTD PMID:24933654 NCBI chr 1:65,544,369...65,551,043
Ensembl chr 1:65,544,373...65,551,043
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] CTD PMID:26600069 NCBI chr20:11,434,062...11,482,880
Ensembl chr20:11,436,267...11,482,051
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 NCBI chr 6:115,170,290...115,306,871
Ensembl chr 6:115,170,865...115,306,871
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Bleomycin results in decreased expression of TUBA1C protein CTD PMID:25933445 NCBI chr 7:140,716,113...140,723,717
Ensembl chr 7:140,716,113...140,723,714
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP Bleomycin results in decreased expression of TUBB2A protein CTD PMID:25933445 NCBI chr17:31,493,145...31,496,827
Ensembl chr17:31,493,107...31,498,651
JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Bleomycin results in decreased expression of TUBB4B protein CTD PMID:25933445 NCBI chr 3:2,441,585...2,444,369
Ensembl chr 3:2,441,733...2,444,281
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression
multiple interactions
ISO Bleomycin results in increased expression of ULK1 protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form]
CTD PMID:31302203 NCBI chr12:51,908,105...51,934,704
Ensembl chr12:51,908,448...51,934,702
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression EXP Bleomycin results in decreased expression of UQCRC1 protein CTD PMID:25933445 NCBI chr 8:117,679,328...117,691,073
Ensembl chr 8:117,679,278...117,691,071
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein increases expression EXP Bleomycin results in increased expression of UQCRHL protein CTD PMID:25933445 NCBI chr 5:134,919,040...134,927,235
Ensembl chr 5:134,919,044...134,927,235
JBrowse link
G Vcl vinculin decreases expression EXP Bleomycin results in decreased expression of VCL protein CTD PMID:25933445 NCBI chr15:3,455,211...3,544,738
Ensembl chr15:3,455,211...3,544,702
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Bleomycin results in increased expression of VEGFA mRNA CTD PMID:26093215 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link
G Vim vimentin increases expression EXP Bleomycin results in increased expression of VIM protein CTD PMID:25933445 NCBI chr17:80,882,715...80,891,200
Ensembl chr17:80,882,666...80,891,212
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 affects response to substance
decreases response to substance
ISO XRCC1 gene polymorphism affects the susceptibility to Bleomycin
XRCC1 results in decreased susceptibility to Bleomycin
CTD PMID:12082022 PMID:20705543 NCBI chr 1:81,412,635...81,441,680
Ensembl chr 1:81,413,353...81,441,678
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Bleomycin CTD PMID:12384553 NCBI chr 9:79,659,275...79,748,050
Ensembl chr 9:79,659,251...79,748,078
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression EXP Bleomycin results in decreased expression of YWHAB protein CTD PMID:25933445 NCBI chr 3:160,391,108...160,399,931
Ensembl chr 3:160,391,106...160,399,931
JBrowse link
bleomycin A5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd10 abhydrolase domain containing 10, depalmitoylase decreases expression ISO bleomycetin results in decreased expression of ABHD10 mRNA CTD PMID:21040473 NCBI chr11:60,053,719...60,068,142
Ensembl chr11:60,054,408...60,066,739
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase decreases expression ISO bleomycetin results in decreased expression of ALG12 mRNA CTD PMID:21040473 NCBI chr 7:129,798,663...129,812,677
Ensembl chr 7:129,798,663...129,812,388
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO bleomycetin results in decreased expression of AMACR mRNA CTD PMID:21040473 NCBI chr 2:60,949,276...60,961,342
Ensembl chr 2:60,949,256...60,961,326
JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression ISO bleomycetin results in decreased expression of ARF4 mRNA CTD PMID:21040473 NCBI chr16:2,338,333...2,354,909
Ensembl chr16:2,338,333...2,354,909
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO bleomycetin results in decreased expression of B2M mRNA CTD PMID:21040473 NCBI chr 3:114,087,287...114,093,311
Ensembl chr 3:114,087,287...114,093,309
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO bleomycetin results in increased expression of BMP2 mRNA CTD PMID:21040473 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression
multiple interactions
decreases response to substance
ISO bleomycetin results in increased expression of CA9 mRNA; bleomycetin results in increased expression of CA9 protein
CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein]
CA9 protein results in decreased susceptibility to bleomycetin
CTD PMID:21040473 NCBI chr 5:59,008,277...59,015,535
Ensembl chr 5:59,008,933...59,015,528
JBrowse link
G Casd1 CAS1 domain containing 1 decreases expression ISO bleomycetin results in decreased expression of CASD1 mRNA CTD PMID:21040473 NCBI chr 4:29,638,280...29,693,151
Ensembl chr 4:29,639,154...29,691,928
JBrowse link
G Casp1 caspase 1 decreases expression ISO bleomycetin results in decreased expression of CASP1 mRNA CTD PMID:21040473 NCBI chr 8:2,605,743...2,614,637
Ensembl chr 8:2,604,962...2,614,631
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Acetazolamide promotes the reaction [bleomycetin results in increased activity of CASP3 protein]; CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein] CTD PMID:21040473 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cdhr5 cadherin-related family member 5 decreases expression ISO bleomycetin results in decreased expression of CDHR5 mRNA CTD PMID:21040473 NCBI chr 1:214,255,118...214,263,848
Ensembl chr 1:214,255,110...214,263,581
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO bleomycetin results in decreased expression of COX7B mRNA CTD PMID:21040473 NCBI chr  X:77,065,427...77,071,676
Ensembl chr  X:77,065,397...77,071,676
JBrowse link
G Cul4a cullin 4A increases expression ISO bleomycetin results in increased expression of CUL4A mRNA CTD PMID:21040473 NCBI chr16:81,718,784...81,756,653
Ensembl chr16:81,719,028...81,756,654
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO bleomycetin results in increased expression of DDIT4 mRNA CTD PMID:21040473 NCBI chr20:29,509,283...29,511,382
Ensembl chr20:29,509,289...29,511,382
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO bleomycetin results in decreased expression of DHCR24 mRNA CTD PMID:21040473 NCBI chr 5:126,164,708...126,188,926
Ensembl chr 5:126,164,674...126,191,206
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO bleomycetin results in decreased expression of DKK1 mRNA CTD PMID:21040473 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO bleomycetin results in decreased expression of DPYSL2 mRNA CTD PMID:21040473 NCBI chr15:43,475,640...43,581,725
Ensembl chr15:43,477,629...43,542,939
JBrowse link
G Ehd4 EH-domain containing 4 increases expression ISO bleomycetin results in increased expression of EHD4 mRNA CTD PMID:21040473 NCBI chr 3:111,877,853...111,941,841
Ensembl chr 3:111,877,853...111,941,841
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 increases expression ISO bleomycetin results in increased expression of EIF4G1 mRNA CTD PMID:21040473 NCBI chr11:83,907,659...83,927,683
Ensembl chr11:83,908,109...83,926,524
JBrowse link
G Emc4 ER membrane protein complex subunit 4 decreases expression ISO bleomycetin results in decreased expression of EMC4 mRNA CTD PMID:21040473 NCBI chr 3:103,852,139...103,857,172
Ensembl chr 3:103,852,139...103,857,158
JBrowse link
G Emc7 ER membrane protein complex subunit 7 decreases expression ISO bleomycetin results in decreased expression of EMC7 mRNA CTD PMID:21040473 NCBI chr 3:103,945,276...103,955,970
Ensembl chr 3:103,945,329...103,956,007
JBrowse link
G Eno2 enolase 2 increases expression ISO bleomycetin results in increased expression of ENO2 mRNA CTD PMID:21040473 NCBI chr 4:157,285,192...157,294,090
Ensembl chr 4:157,285,179...157,294,047
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO bleomycetin results in decreased expression of FBN2 mRNA CTD PMID:21040473 NCBI chr18:53,068,495...53,272,254
Ensembl chr18:53,068,495...53,181,503
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression ISO bleomycetin results in increased expression of FKBP1A mRNA CTD PMID:21040473 NCBI chr 3:147,042,944...147,062,725
Ensembl chr 3:147,042,944...147,062,724
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 decreases expression ISO bleomycetin results in decreased expression of FKBP9 mRNA CTD PMID:21040473 NCBI chr 4:87,167,514...87,234,198
Ensembl chr 4:87,167,514...87,234,197
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 increases expression ISO bleomycetin results in increased expression of FRS3 mRNA CTD PMID:21040473 NCBI chr 9:15,297,794...15,306,850
Ensembl chr 9:15,297,895...15,306,465
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 decreases expression ISO bleomycetin results in decreased expression of GALNT10 mRNA CTD PMID:21040473 NCBI chr10:43,067,316...43,208,992
Ensembl chr10:43,067,299...43,210,427
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO bleomycetin results in increased expression of GCLC mRNA CTD PMID:21040473 NCBI chr 8:85,059,051...85,097,471
Ensembl chr 8:85,059,051...85,097,468
JBrowse link
G Gng11 G protein subunit gamma 11 decreases expression ISO bleomycetin results in decreased expression of GNG11 mRNA CTD PMID:21040473 NCBI chr 4:28,989,170...28,994,610
Ensembl chr 4:28,989,115...28,993,621
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO bleomycetin results in decreased expression of GSTK1 mRNA CTD PMID:21040473 NCBI chr 4:71,621,777...71,626,096
Ensembl chr 4:71,621,729...71,626,107
JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO bleomycetin results in decreased expression of H2BC12 mRNA CTD PMID:21040473 NCBI chr17:44,527,421...44,527,801
Ensembl chr17:44,527,421...44,527,801
JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression ISO bleomycetin results in increased expression of HNRNPAB mRNA CTD PMID:21040473 NCBI chr10:34,955,713...34,961,662
Ensembl chr10:34,955,716...34,961,608
JBrowse link
G Hoxb7 homeo box B7 decreases expression ISO bleomycetin results in decreased expression of HOXB7 mRNA CTD PMID:21040473 NCBI chr10:84,135,224...84,138,642
Ensembl chr10:84,135,116...84,138,637
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO bleomycetin results in decreased expression of HSPH1 mRNA CTD PMID:21040473 NCBI chr12:6,322,685...6,341,898
Ensembl chr12:6,322,668...6,341,902
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO bleomycetin results in decreased expression of IDH3A mRNA CTD PMID:21040473 NCBI chr 8:59,164,601...59,183,899
Ensembl chr 8:59,164,572...59,183,908
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO bleomycetin results in decreased expression of IDI1 mRNA CTD PMID:21040473 NCBI chr17:57,976,266...57,984,036
Ensembl chr17:57,976,268...57,984,036
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO bleomycetin results in increased expression of ITGA5 mRNA CTD PMID:21040473 NCBI chr 7:144,970,444...144,993,652
Ensembl chr 7:144,970,444...144,993,652
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO bleomycetin results in increased expression of ITGB5 mRNA CTD PMID:21040473 NCBI chr11:70,056,500...70,172,164
Ensembl chr11:70,056,500...70,172,372
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO bleomycetin results in increased expression of ITPR1 mRNA CTD PMID:21040473 NCBI chr 4:140,247,297...140,580,749
Ensembl chr 4:140,247,313...140,580,748
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO bleomycetin results in decreased expression of KAT6B mRNA CTD PMID:21040473 NCBI chr15:2,811,933...2,966,833
Ensembl chr15:2,813,537...2,966,576
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 increases expression ISO bleomycetin results in increased expression of LYPD3 mRNA CTD PMID:21040473 NCBI chr 1:81,499,856...81,504,306
Ensembl chr 1:81,499,821...81,504,318
JBrowse link
G Mageb2 MAGE family member B2 decreases expression ISO bleomycetin results in decreased expression of MAGEB2 mRNA CTD PMID:21040473 NCBI chr  X:54,804,987...54,806,956 JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 increases expression ISO bleomycetin results in increased expression of MAN1B1 mRNA CTD PMID:21040473 NCBI chr 3:2,547,259...2,569,051
Ensembl chr 3:2,547,986...2,569,049
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO bleomycetin results in increased expression of MCM2 mRNA CTD PMID:21040473 NCBI chr 4:120,825,699...120,840,221
Ensembl chr 4:120,825,699...120,840,111
JBrowse link
G Med11 mediator complex subunit 11 decreases expression ISO bleomycetin results in decreased expression of MED11 mRNA CTD PMID:21040473 NCBI chr10:57,057,272...57,059,415
Ensembl chr10:57,057,608...57,059,403
JBrowse link
G Metrn meteorin, glial cell differentiation regulator increases expression ISO bleomycetin results in increased expression of METRN mRNA CTD PMID:21040473 NCBI chr10:15,164,439...15,166,457
Ensembl chr10:15,164,439...15,166,457
JBrowse link
G Mt2A metallothionein 2A increases expression ISO bleomycetin results in increased expression of MT2A mRNA; bleomycetin results in increased expression of MT2A protein CTD PMID:21040473 NCBI chr19:11,307,966...11,308,740
Ensembl chr19:11,307,967...11,308,740
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO bleomycetin results in increased expression of MYC mRNA CTD PMID:21040473 NCBI chr 7:102,586,313...102,591,240
Ensembl chr 7:102,586,313...102,591,240
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 increases expression ISO bleomycetin results in increased expression of NCBP2 mRNA CTD PMID:21040473 NCBI chr11:72,071,838...72,103,087
Ensembl chr11:72,921,282...72,929,003
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO bleomycetin results in increased expression of NDRG1 mRNA CTD PMID:21040473 NCBI chr 7:107,734,326...107,775,701
Ensembl chr 7:107,734,323...107,775,714
JBrowse link
G Nop10 NOP10 ribonucleoprotein decreases expression ISO bleomycetin results in decreased expression of NOLA3 mRNA CTD PMID:21040473 NCBI chr 3:103,747,654...103,748,739
Ensembl chr 3:103,747,654...103,748,739
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO bleomycetin results in increased expression of NOP56 mRNA CTD PMID:21040473 NCBI chr 3:122,803,726...122,808,564
Ensembl chr 3:122,803,772...122,808,558
JBrowse link
G Nrdc nardilysin convertase decreases expression ISO bleomycetin results in decreased expression of NRDC mRNA CTD PMID:21040473 NCBI chr 5:128,629,949...128,694,209
Ensembl chr 5:128,629,942...128,694,060
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO bleomycetin results in increased expression of P4HA1 mRNA CTD PMID:21040473 NCBI chr20:28,920,616...28,972,576
Ensembl chr20:28,920,616...28,971,966
JBrowse link
G Parn poly(A)-specific ribonuclease increases expression ISO bleomycetin results in increased expression of PARN mRNA CTD PMID:21040473 NCBI chr10:1,309,724...1,461,123
Ensembl chr10:1,308,414...1,461,269
JBrowse link
G Pdgfa platelet derived growth factor subunit A decreases expression ISO bleomycetin results in decreased expression of PDGFA mRNA CTD PMID:21040473 NCBI chr12:17,734,141...17,756,186
Ensembl chr12:17,734,133...17,755,285
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO bleomycetin results in decreased expression of PGD mRNA CTD PMID:21040473 NCBI chr 5:165,966,128...165,982,327 JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 increases expression ISO bleomycetin results in increased expression of PGRMC2 mRNA CTD PMID:21040473 NCBI chr 2:127,986,106...128,002,005
Ensembl chr 2:127,986,109...128,002,005
JBrowse link
G Pkn3 protein kinase N3 decreases expression ISO bleomycetin results in decreased expression of PKN3 mRNA CTD PMID:21040473 NCBI chr 3:8,628,033...8,656,464
Ensembl chr 3:8,628,033...8,659,117
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression ISO bleomycetin results in increased expression of PPP2R2B mRNA CTD PMID:21040473 NCBI chr18:36,985,709...37,421,383
Ensembl chr18:36,985,714...37,245,809
JBrowse link
G Pqbp1 polyglutamine binding protein 1 decreases expression ISO bleomycetin results in decreased expression of PQBP1 mRNA CTD PMID:21040473 NCBI chr  X:15,448,570...15,453,130
Ensembl chr  X:15,348,138...15,453,130
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO bleomycetin results in decreased expression of PTGES mRNA CTD PMID:21040473 NCBI chr 3:9,727,408...9,738,752
Ensembl chr 3:9,727,408...9,738,752
JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO bleomycetin results in increased expression of RAB31 mRNA CTD PMID:21040473 NCBI chr 9:113,370,072...113,504,606
Ensembl chr 9:113,370,033...113,504,605
JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO bleomycetin results in decreased expression of RBP4 mRNA CTD PMID:21040473 NCBI chr 1:256,806,476...256,813,678
Ensembl chr 1:256,806,472...256,813,711
JBrowse link
G Rps4x ribosomal protein S4, X-linked decreases expression ISO bleomycetin results in decreased expression of RPS4X mRNA CTD PMID:21040473 NCBI chr  X:72,074,108...72,078,551
Ensembl chr  X:72,074,108...72,078,551
Ensembl chr 4:72,074,108...72,078,551
JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 increases expression ISO bleomycetin results in increased expression of RSL1D1 mRNA CTD PMID:21040473 NCBI chr10:4,375,329...4,387,195
Ensembl chr10:4,356,915...4,390,030
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 increases expression ISO bleomycetin results in increased expression of RUVBL1 mRNA CTD PMID:21040473 NCBI chr 4:120,411,917...120,447,458
Ensembl chr 4:120,411,991...120,447,455
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha decreases expression ISO bleomycetin results in decreased expression of SCNN1A mRNA CTD PMID:21040473 NCBI chr 4:157,834,339...157,860,472
Ensembl chr 4:157,836,912...157,860,049
JBrowse link
G Sdc4 syndecan 4 increases expression ISO bleomycetin results in increased expression of SDC4 mRNA CTD PMID:21040473 NCBI chr 3:160,872,503...160,891,190
Ensembl chr 3:160,872,503...160,891,190
JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression ISO bleomycetin results in increased expression of SFPQ mRNA CTD PMID:21040473 NCBI chr 5:145,079,803...145,088,517
Ensembl chr 5:145,079,803...145,088,498
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO bleomycetin results in increased expression of SGK1 mRNA CTD PMID:21040473 NCBI chr 1:24,185,451...24,302,309
Ensembl chr 1:24,185,435...24,302,298
JBrowse link
G Sltm SAFB-like, transcription modulator decreases expression ISO bleomycetin results in decreased expression of SLTM mRNA CTD PMID:21040473 NCBI chr 8:76,977,698...77,022,847
Ensembl chr 8:76,977,822...77,022,837
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO bleomycetin results in increased expression of SOCS3 mRNA CTD PMID:21040473 NCBI chr10:106,973,863...106,976,969
Ensembl chr10:106,975,178...106,976,040
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO bleomycetin results in increased expression of SRXN1 mRNA CTD PMID:21040473 NCBI chr 3:147,608,850...147,614,410
Ensembl chr 3:147,609,095...147,632,801
JBrowse link
G Tcp1 t-complex 1 decreases expression ISO bleomycetin results in decreased expression of TCP1 mRNA CTD PMID:21040473 NCBI chr 1:48,025,664...48,033,343
Ensembl chr 1:48,025,663...48,033,396
JBrowse link
G Tma7 translation machinery associated 7 homolog decreases expression ISO bleomycetin results in decreased expression of TMA7 mRNA CTD PMID:21040473 NCBI chr 8:117,815,725...117,820,422
Ensembl chr 8:117,815,725...117,820,413
JBrowse link
G Tmem230 transmembrane protein 230 increases expression ISO bleomycetin results in increased expression of TMEM230 mRNA CTD PMID:21040473 NCBI chr 3:124,870,867...124,879,274
Ensembl chr 3:124,870,869...124,879,216
JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO bleomycetin results in increased expression of TPM4 mRNA CTD PMID:21040473 NCBI chr16:19,385,810...19,399,851
Ensembl chr16:19,385,736...19,399,903
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO bleomycetin results in increased expression of TSC22D1 mRNA CTD PMID:21040473 NCBI chr15:58,554,358...58,658,156
Ensembl chr15:58,554,374...58,658,153
JBrowse link
G Upp1 uridine phosphorylase 1 decreases expression ISO bleomycetin results in decreased expression of UPP1 mRNA CTD PMID:21040473 NCBI chr14:89,314,234...89,334,060
Ensembl chr14:89,314,176...89,334,276
JBrowse link
G Usp37 ubiquitin specific peptidase 37 decreases expression ISO bleomycetin results in decreased expression of USP37 mRNA CTD PMID:21040473 NCBI chr 9:81,717,626...81,818,421
Ensembl chr 9:81,716,876...81,772,851
JBrowse link
G Uxt ubiquitously-expressed, prefoldin-like chaperone decreases expression ISO bleomycetin results in decreased expression of UXT mRNA CTD PMID:21040473 NCBI chr  X:1,275,402...1,287,781
Ensembl chr  X:1,275,612...1,287,512
JBrowse link
G Zfp541 zinc finger protein 541 decreases expression ISO bleomycetin results in decreased expression of ZNF541 mRNA CTD PMID:21040473 NCBI chr 1:77,957,188...77,993,816
Ensembl chr 1:77,967,755...77,992,027
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19810
    role 19758
      biological role 19758
        antimicrobial agent 17329
          bleomycin 587
            bleomycin A2 510
            bleomycin A5 83
            bleomycin B2 0
            bleomycin hydrochloride 0
            bleomycin sulfate 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19810
    subatomic particle 19808
      composite particle 19808
        hadron 19808
          baryon 19808
            nucleon 19808
              atomic nucleus 19808
                atom 19808
                  main group element atom 19696
                    p-block element atom 19696
                      carbon group element atom 19599
                        carbon atom 19588
                          organic molecular entity 19588
                            organic group 18527
                              organic divalent group 18520
                                organodiyl group 18520
                                  carbonyl group 18427
                                    carbonyl compound 18427
                                      carboxylic acid 18108
                                        carboacyl group 17369
                                          univalent carboacyl group 17369
                                            carbamoyl group 17156
                                              carboxamide 17156
                                                peptide 9395
                                                  peptide antibiotic 1666
                                                    chelate-forming peptide 587
                                                      bleomycin 587
                                                        bleomycin A2 510
                                                        bleomycin A5 83
                                                        bleomycin B2 0
                                                        bleomycin hydrochloride 0
                                                        bleomycin sulfate 0
paths to the root