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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chelate-forming peptide
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Accession:CHEBI:23089 term browser browse the term



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bleomycin A2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE protein] CTD PMID:20581171 NCBI chr10:90,910,316...90,930,437
Ensembl chr10:90,910,316...90,931,131
JBrowse link
G Ace2 angiotensin I converting enzyme 2 multiple interactions
decreases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in decreased expression of ACE2 mRNA] CTD PMID:20581171 NCBI chr  X:30,293,597...30,340,961
Ensembl chr  X:30,293,589...30,340,977
JBrowse link
G Acta2 actin alpha 2, smooth muscle increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of ACTA2 mRNA; Bleomycin results in increased expression of ACTA2 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; andrographolide inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; montelukast inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; (3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; [Arsenic Trioxide co-treated with Bleomycin] results in decreased expression of ACTA2 mRNA; [Bleomycin co-treated with Soot] results in increased expression of ACTA2 protein; Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; celastrol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of and results in increased phosphorylation of ACTA2 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of ACTA2 protein]
CTD PMID:14609568 PMID:17177178 PMID:21381050 PMID:23656969 PMID:24762191 More... NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
JBrowse link
G Actn1 actinin, alpha 1 decreases expression EXP Bleomycin results in decreased expression of ACTN1 protein CTD PMID:25933445 NCBI chr 6:98,998,553...99,093,334
Ensembl chr 6:98,998,556...99,093,251
JBrowse link
G Actn4 actinin alpha 4 decreases expression EXP Bleomycin results in decreased expression of ACTN4 protein CTD PMID:25933445 NCBI chr 1:84,182,783...84,251,867
Ensembl chr 1:84,182,788...84,251,847
JBrowse link
G Adam17 ADAM metallopeptidase domain 17 multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ADAM17 protein CTD PMID:22687607 NCBI chr 6:40,872,936...40,920,700
Ensembl chr 6:40,872,856...40,920,639
JBrowse link
G Adra1b adrenoceptor alpha 1B decreases expression EXP Bleomycin results in decreased expression of ADRA1B mRNA CTD PMID:15808516 NCBI chr10:28,255,025...28,373,418
Ensembl chr10:28,255,025...28,312,919
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions
decreases expression
EXP protocatechualdehyde inhibits the reaction [Bleomycin results in decreased expression of AGER protein] CTD PMID:25582705 PMID:25933445 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Agtr1a angiotensin II receptor, type 1a multiple interactions
increases expression
EXP angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of AGTR1 protein] CTD PMID:20581171 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
JBrowse link
G Ahsg alpha-2-HS-glycoprotein increases expression EXP Bleomycin results in increased expression of AHSG protein CTD PMID:25933445 NCBI chr11:78,117,903...78,145,956 JBrowse link
G Akt1 AKT serine/threonine kinase 1 increases phosphorylation ISO Bleomycin results in increased phosphorylation of AKT1 protein CTD PMID:22687607 PMID:26520185 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alb albumin increases expression EXP Bleomycin results in increased expression of ALB protein CTD PMID:25933445 NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
JBrowse link
G Aldh1a1 aldehyde dehydrogenase 1 family, member A1 decreases expression EXP Bleomycin results in decreased expression of ALDH1A1 protein CTD PMID:25933445 NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
JBrowse link
G Aldoc aldolase, fructose-bisphosphate C multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ALDOC protein CTD PMID:29733421 NCBI chr10:63,217,477...63,221,066
Ensembl chr10:63,217,451...63,221,066
JBrowse link
G Ankrd1 ankyrin repeat domain 1 increases expression ISO Bleomycin results in increased expression of ANKRD1 mRNA CTD PMID:26345256 NCBI chr 1:233,815,851...233,834,891
Ensembl chr 1:233,815,851...233,834,919
JBrowse link
G Anp32e acidic nuclear phosphoprotein 32 family member E increases expression EXP Bleomycin results in increased expression of ANP32E protein CTD PMID:25933445 NCBI chr 2:183,472,600...183,489,057
Ensembl chr 2:183,472,609...183,489,054
JBrowse link
G Anxa2 annexin A2 decreases expression EXP Bleomycin results in decreased expression of ANXA2 protein CTD PMID:25933445 NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
JBrowse link
G Anxa3 annexin A3 decreases expression EXP Bleomycin results in decreased expression of ANXA3 protein CTD PMID:25933445 NCBI chr14:12,727,708...12,781,717
Ensembl chr14:12,719,795...12,781,617
JBrowse link
G Anxa4 annexin A4 decreases expression EXP Bleomycin results in decreased expression of ANXA4 protein CTD PMID:25933445 NCBI chr 4:119,184,378...119,241,183
Ensembl chr 4:119,184,374...119,241,161
JBrowse link
G Anxa5 annexin A5 increases expression EXP Bleomycin results in increased expression of ANXA5 protein CTD PMID:25933445 NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369
JBrowse link
G Anxa6 annexin A6 decreases expression EXP Bleomycin results in decreased expression of ANXA6 protein CTD PMID:25933445 NCBI chr10:39,101,395...39,156,483
Ensembl chr10:39,097,109...39,156,433
JBrowse link
G Anxa7 annexin A7 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ANXA7 protein CTD PMID:29733421 NCBI chr15:3,821,798...3,849,659
Ensembl chr15:3,821,845...3,849,385
JBrowse link
G Aqp1 aquaporin 1 decreases expression EXP Bleomycin results in decreased expression of AQP1 mRNA CTD PMID:15782499 NCBI chr 4:84,482,512...84,494,690
Ensembl chr 4:84,482,512...84,494,690
JBrowse link
G Areg amphiregulin increases expression ISO Bleomycin results in increased expression of AREG mRNA CTD PMID:26817844 NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
JBrowse link
G Arg1 arginase 1 increases expression ISO Bleomycin results in increased expression of ARG1 mRNA; Bleomycin results in increased expression of ARG1 protein CTD PMID:26345256 PMID:26526764 PMID:33647319 NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
JBrowse link
G Atm ATM serine/threonine kinase multiple interactions
increases phosphorylation
ISO 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of ATM protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein]]; Bleomycin promotes the reaction [resveratrol results in increased phosphorylation of ATM protein]; resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of ATM protein] CTD PMID:24933654 NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437
JBrowse link
G Atp5f1b ATP synthase F1 subunit beta decreases expression EXP Bleomycin results in decreased expression of ATP5F1B protein CTD PMID:25933445 NCBI chr 7:515,454...521,858
Ensembl chr 7:515,460...567,273
JBrowse link
G Atp5if1 ATP synthase inhibitory factor subunit 1 increases expression EXP Bleomycin results in increased expression of ATPIF1 protein CTD PMID:25933445 NCBI chr 5:144,738,950...144,742,668
Ensembl chr 5:144,738,950...144,742,668
JBrowse link
G Atp5me ATP synthase membrane subunit e multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of ATP5ME protein CTD PMID:29733421 NCBI chr14:1,319,868...1,320,996
Ensembl chr14:1,319,868...1,321,013
JBrowse link
G Atp5po ATP synthase peripheral stalk subunit OSCP decreases expression ISO Bleomycin results in decreased expression of ATP5O protein CTD PMID:29733421 NCBI chr11:31,165,218...31,171,530
Ensembl chr11:31,165,217...31,171,592
JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A multiple interactions
decreases expression
ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of ATP6V1A protein
Bleomycin results in decreased expression of ATP6V1A protein
CTD PMID:29733421 NCBI chr11:56,561,444...56,614,694
Ensembl chr11:56,560,974...56,614,694
JBrowse link
G Avpr1a arginine vasopressin receptor 1A decreases expression EXP Bleomycin results in decreased expression of AVPR1A mRNA CTD PMID:15808516 NCBI chr 7:58,114,306...58,118,230
Ensembl chr 7:58,114,284...58,122,215
JBrowse link
G Basp1 brain abundant, membrane attached signal protein 1 increases expression EXP Bleomycin results in increased expression of BASP1 protein CTD PMID:25933445 NCBI chr 2:75,816,130...75,863,801
Ensembl chr 2:75,816,122...75,864,043
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of BAX protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of BAX mRNA]
Bleomycin inhibits the reaction [Azacitidine results in increased expression of BAX mRNA]
Bleomycin results in increased expression of BAX mRNA; Bleomycin results in increased expression of BAX protein
CTD PMID:23656969 PMID:26093215 PMID:32278510 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
increases expression
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in decreased expression of BCL2 mRNA; allyl sulfide promotes the reaction [Bleomycin results in increased expression of BCL2 protein]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of BCL2 mRNA]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 mRNA]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of BCL2 protein]
[Polyphenols co-treated with Bleomycin] results in increased expression of BCL2 mRNA; [Tea co-treated with Bleomycin] results in increased expression of BCL2 mRNA
CTD PMID:23656969 PMID:24822179 PMID:26093215 PMID:26800624 PMID:32278510 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl6b BCL6B, transcription repressor multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of BCL6B mRNA CTD PMID:29733421 NCBI chr10:54,940,908...54,947,022
Ensembl chr10:54,940,909...54,945,974
JBrowse link
G Birc2 baculoviral IAP repeat-containing 2 decreases response to substance
increases expression
ISO
EXP
BIRC2 protein results in decreased susceptibility to Bleomycin
Bleomycin results in increased expression of BIRC2 protein
CTD PMID:10815900 PMID:15371238 NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 increases expression ISO Bleomycin results in increased expression of BIRC5 mRNA CTD PMID:26345256 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Blmh bleomycin hydrolase affects response to substance ISO BLMH gene polymorphism affects the susceptibility to Bleomycin CTD PMID:12082022 NCBI chr10:61,772,112...61,815,212
Ensembl chr10:61,758,478...61,815,212
JBrowse link
G Bmp7 bone morphogenetic protein 7 decreases expression ISO Bleomycin results in decreased expression of BMP7 mRNA CTD PMID:29408570 NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788
JBrowse link
G Bscl2 BSCL2 lipid droplet biogenesis associated, seipin increases expression ISO Bleomycin results in increased expression of BSCL2 mRNA CTD PMID:22003191 NCBI chr 1:205,731,814...205,743,430
Ensembl chr 1:205,733,872...205,743,421
JBrowse link
G C1qb complement C1q B chain increases expression ISO Bleomycin results in increased expression of C1QB mRNA CTD PMID:26345256 NCBI chr 5:149,118,843...149,124,394
Ensembl chr 5:149,118,846...149,124,407
JBrowse link
G Cald1 caldesmon 1 increases expression EXP Bleomycin results in increased expression of CALD1 protein CTD PMID:25933445 NCBI chr 4:63,265,781...63,446,936
Ensembl chr 4:63,265,942...63,446,932
JBrowse link
G Calml3 calmodulin-like 3 decreases expression EXP Bleomycin results in decreased expression of CALML3 protein CTD PMID:25933445 NCBI chr17:66,419,844...66,423,083
Ensembl chr17:66,419,882...66,423,175
JBrowse link
G Calr calreticulin increases expression EXP Bleomycin results in increased expression of CALR protein CTD PMID:25933445 NCBI chr19:23,308,525...23,313,420
Ensembl chr19:23,308,351...23,313,414
JBrowse link
G Calu calumenin increases expression EXP Bleomycin results in increased expression of CALU protein CTD PMID:25933445 NCBI chr 4:57,949,086...57,976,589
Ensembl chr 4:57,948,997...57,976,593
JBrowse link
G Car1 carbonic anhydrase 1 decreases expression EXP Bleomycin results in decreased expression of CA1 protein CTD PMID:25933445 NCBI chr 2:86,829,436...86,872,209
Ensembl chr 2:86,861,897...86,872,208
JBrowse link
G Car2 carbonic anhydrase 2 decreases expression EXP Bleomycin results in decreased expression of CA2 protein CTD PMID:25933445 NCBI chr 2:86,741,625...86,756,766
Ensembl chr 2:86,741,626...86,756,818
JBrowse link
G Carhsp1 calcium regulated heat stable protein 1 increases expression EXP Bleomycin results in increased expression of CARHSP1 protein CTD PMID:25933445 NCBI chr10:6,946,036...6,960,556
Ensembl chr10:6,946,959...7,020,019
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases activity
EXP
ISO
[Bleomycin co-treated with Bee Venoms] results in increased expression of CASP3 mRNA; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of CASP3 protein]; Bleomycin results in increased cleavage of and results in increased activity of CASP3 protein; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of CASP3 mRNA]
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP3 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP3 mRNA
Bleomycin results in increased expression of CASP3 mRNA; Bleomycin results in increased expression of CASP3 protein
Bleomycin results in increased activity of CASP3 protein
CTD PMID:15371238 PMID:22687607 PMID:23656969 PMID:24822179 PMID:26093215 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions ISO [Polyphenols co-treated with Bleomycin] results in increased expression of CASP8 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP8 mRNA CTD PMID:26800624 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP
ISO
Bleomycin results in increased cleavage of and results in increased activity of CASP9 protein
[Polyphenols co-treated with Bleomycin] results in increased expression of CASP9 mRNA; [Tea co-treated with Bleomycin] results in increased expression of CASP9 mRNA
Bleomycin results in increased activity of CASP9 protein
CTD PMID:15371238 PMID:22687607 PMID:26800624 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cast calpastatin increases expression EXP Bleomycin results in increased expression of CAST protein CTD PMID:25933445 NCBI chr 2:3,973,112...4,082,658
Ensembl chr 2:3,973,112...4,082,659
JBrowse link
G Cat catalase increases response to substance
decreases activity
multiple interactions
increases expression
ISO
EXP
CAT protein results in increased susceptibility to Bleomycin
Bleomycin results in decreased activity of CAT
celastrol inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]
Bleomycin results in decreased expression of and results in decreased activity of CAT protein; caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of CAT protein]; Oils, Volatile inhibits the reaction [Bleomycin results in decreased activity of CAT protein]
CTD PMID:8317554 PMID:10751631 PMID:23570914 PMID:26768587 PMID:28850077 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 decreases expression EXP Bleomycin results in decreased expression of CAV1 protein CTD PMID:25933445 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cavin2 caveolae associated protein 2 decreases expression EXP Bleomycin results in decreased expression of CAVIN2 protein CTD PMID:25933445 NCBI chr 9:50,302,079...50,314,096
Ensembl chr 9:50,301,206...50,314,147
JBrowse link
G Cckar cholecystokinin A receptor decreases expression EXP Bleomycin results in decreased expression of CCKAR mRNA CTD PMID:15808516 NCBI chr14:57,292,397...57,300,747
Ensembl chr14:57,292,397...57,300,747
JBrowse link
G Ccl11 C-C motif chemokine ligand 11 increases expression
decreases expression
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CCL11 mRNA; Bleomycin results in increased expression of CCL11 protein
Bleomycin results in decreased expression of CCL11 mRNA
CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]
CCL11 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:16314464 PMID:29720568 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926
JBrowse link
G Ccl12 chemokine (C-C motif) ligand 12 increases expression
decreases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL12 mRNA
Bleomycin results in decreased expression of CCL12 mRNA
[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of CCL12 mRNA]
CTD PMID:28434932 PMID:29720568 NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
JBrowse link
G Ccl17 C-C motif chemokine ligand 17 increases expression ISO Bleomycin results in increased expression of CCL17 mRNA; Bleomycin results in increased expression of CCL17 protein CTD PMID:26345256 PMID:29175452 NCBI chr19:10,202,317...10,203,768
Ensembl chr19:10,202,128...10,203,819
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of CCL2 mRNA; Bleomycin results in increased expression of CCL2 protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CCL2 protein
Bleomycin results in decreased expression of CCL2 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 mRNA]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CCL2 protein]
CTD PMID:15541506 PMID:16314464 PMID:17177178 PMID:19147827 PMID:26209236 More... NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
JBrowse link
G Ccl3 C-C motif chemokine ligand 3 increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of CCL3 mRNA
Bleomycin results in decreased expression of CCL3 protein
[Bleomycin co-treated with Tobacco Smoke Pollution] affects the expression of CCL3 protein
Bleomycin results in decreased expression of CCL3 mRNA
Calcitriol inhibits the reaction [Bleomycin results in increased expression of CCL3 mRNA]
CTD PMID:26520185 PMID:29720568 PMID:32828905 PMID:33516805 NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
JBrowse link
G Ccl4 C-C motif chemokine ligand 4 decreases expression ISO Bleomycin results in decreased expression of CCL4 mRNA CTD PMID:29720568 NCBI chr10:68,466,469...68,467,941
Ensembl chr10:68,452,052...68,468,231
JBrowse link
G Ccl5 C-C motif chemokine ligand 5 increases expression
multiple interactions
ISO Bleomycin results in increased expression of CCL5 mRNA
SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]
CTD PMID:32828905 NCBI chr10:68,322,826...68,327,365
Ensembl chr10:68,322,829...68,327,377
JBrowse link
G Ccl6 C-C motif chemokine ligand 6 increases expression ISO Bleomycin results in increased expression of CCL6 protein CTD PMID:29175452 NCBI chr10:68,381,179...68,385,811
Ensembl chr10:68,380,188...68,384,001
JBrowse link
G Ccl7 C-C motif chemokine ligand 7 decreases expression ISO Bleomycin results in decreased expression of CCL7 mRNA CTD PMID:29720568 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
JBrowse link
G Ccn2 cellular communication network factor 2 multiple interactions
increases expression
ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of CCN2 protein]
Bleomycin results in increased expression of CCN2 mRNA; Bleomycin results in increased expression of CCN2 protein
CTD PMID:19080365 PMID:26817844 PMID:27153807 PMID:28434932 PMID:32032644 NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
JBrowse link
G Ccng1 cyclin G1 increases expression ISO Bleomycin results in increased expression of CCNG1 mRNA CTD PMID:26345256 NCBI chr10:25,176,231...25,182,604
Ensembl chr10:25,176,234...25,181,641
JBrowse link
G Ccr2 C-C motif chemokine receptor 2 multiple interactions
increases expression
decreases response to substance
ISO CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]
Bleomycin results in increased expression of CCR2 mRNA
CCR2 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:14609568 PMID:29033951 NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
JBrowse link
G Ccr3 C-C motif chemokine receptor 3 increases expression ISO Bleomycin results in increased expression of CCR3 mRNA; Bleomycin results in increased expression of CCR3 protein CTD PMID:16314464 NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
JBrowse link
G Ccr5 C-C motif chemokine receptor 5 affects expression ISO Bleomycin affects the expression of CCR5 mRNA CTD PMID:26345256 NCBI chr 8:123,752,423...123,757,538
Ensembl chr 8:123,752,325...123,759,260
JBrowse link
G Cct8 chaperonin containing TCP1 subunit 8 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of CCT8 protein CTD PMID:29733421 NCBI chr11:26,710,370...26,722,079
Ensembl chr11:26,710,370...26,722,079
JBrowse link
G Cd36 CD36 molecule decreases expression ISO Bleomycin results in decreased expression of CD36 mRNA CTD PMID:29408570 NCBI chr 4:17,317,343...17,410,084 JBrowse link
G Cd44 CD44 molecule (Indian blood group) multiple interactions
increases expression
ISO honokiol inhibits the reaction [Bleomycin results in increased expression of CD44 protein] CTD PMID:32032644 NCBI chr 3:89,155,850...89,244,615
Ensembl chr 3:89,157,058...89,244,620
JBrowse link
G Cd86 CD86 molecule decreases expression ISO Bleomycin results in decreased expression of CD86 mRNA CTD PMID:29720568 NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818
JBrowse link
G Cdc20 cell division cycle 20 increases expression ISO Bleomycin results in increased expression of CDC20 mRNA CTD PMID:26345256 NCBI chr 5:131,966,203...131,970,406
Ensembl chr 5:131,966,215...131,970,512
JBrowse link
G Cdh1 cadherin 1 multiple interactions
decreases expression
ISO 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]; honokiol inhibits the reaction [Bleomycin results in decreased expression of CDH1 protein]
Bleomycin results in decreased expression of CDH1 mRNA; Bleomycin results in decreased expression of CDH1 protein
CTD PMID:28300665 PMID:28694203 PMID:32032644 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A increases expression ISO Bleomycin results in increased expression of CDKN1A mRNA CTD PMID:26345256 PMID:29720568 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta increases expression
increases response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of CEBPB mRNA
CEBPB protein results in increased susceptibility to Bleomycin
CEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]
CEBPB gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:17177178 PMID:21998664 NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473
JBrowse link
G Cemip2 cell migration inducing hyaluronidase 2 decreases expression ISO Bleomycin results in decreased expression of CEMIP2 mRNA CTD PMID:33770205 NCBI chr 1:219,330,295...219,407,760
Ensembl chr 1:219,337,985...219,407,760
JBrowse link
G Ces1d carboxylesterase 1D decreases expression EXP Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 NCBI chr19:13,873,490...13,912,035 JBrowse link
G Cfl1 cofilin 1 increases expression EXP Bleomycin results in increased expression of CFL1 protein CTD PMID:25933445 NCBI chr 1:202,796,012...202,801,337
Ensembl chr 1:202,786,627...202,817,587
JBrowse link
G Chek2 checkpoint kinase 2 increases phosphorylation
multiple interactions
ISO Bleomycin results in increased phosphorylation of CHEK2 protein
resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of CHEK2 protein]
CTD PMID:24933654 NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286
JBrowse link
G Chrnb2 cholinergic receptor nicotinic beta 2 subunit decreases expression EXP Bleomycin results in decreased expression of CHRNB2 mRNA CTD PMID:15808516 NCBI chr 2:175,181,402...175,189,619
Ensembl chr 2:175,181,402...175,189,619
JBrowse link
G Ckb creatine kinase B increases expression EXP Bleomycin results in increased expression of CKB protein CTD PMID:25933445 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Clcn5 chloride voltage-gated channel 5 increases expression EXP Bleomycin results in increased expression of CLCN5 mRNA CTD PMID:15808516 NCBI chr  X:15,185,353...15,339,977
Ensembl chr  X:15,185,451...15,334,264
JBrowse link
G Cldn4 claudin 4 increases expression ISO Bleomycin results in increased expression of CLDN4 mRNA CTD PMID:26345256 NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436
JBrowse link
G Clic4 chloride intracellular channel 4 decreases expression EXP Bleomycin results in decreased expression of CLIC4 protein CTD PMID:25933445 NCBI chr 5:147,456,819...147,513,278
Ensembl chr 5:147,453,712...147,513,452
JBrowse link
G Clic5 chloride intracellular channel 5 decreases expression EXP Bleomycin results in decreased expression of CLIC5 protein CTD PMID:25933445 NCBI chr 9:16,710,980...16,813,427
Ensembl chr 9:16,710,980...16,813,427
JBrowse link
G Cltc clathrin heavy chain decreases expression EXP Bleomycin results in decreased expression of CLTC protein CTD PMID:25933445 NCBI chr10:71,517,661...71,574,591
Ensembl chr10:71,517,663...71,573,737
JBrowse link
G Cnr1 cannabinoid receptor 1 decreases expression EXP Bleomycin results in decreased expression of CNR1 mRNA CTD PMID:15808516 NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
JBrowse link
G Col1a1 collagen type I alpha 1 chain multiple interactions
increases expression
decreases expression
ISO
EXP
[Bleomycin co-treated with Soot] results in increased expression of COL1A1 protein; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Arsenic Trioxide inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Enalapril inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; icaritin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
Bleomycin results in increased expression of COL1A1 mRNA; Bleomycin results in increased expression of COL1A1 protein
Bleomycin results in decreased expression of COL1A1 protein
Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of COL1A1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]
CTD PMID:12003776 PMID:14609568 PMID:17434272 PMID:19147827 PMID:24762191 More... NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col1a2 collagen type I alpha 2 chain increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of COL1A2 mRNA
Bleomycin results in decreased expression of COL1A2 protein
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of COL1A2 mRNA]
CTD PMID:19147827 PMID:25933445 NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
JBrowse link
G Col3a1 collagen type III alpha 1 chain decreases expression
multiple interactions
increases expression
EXP
ISO
Bleomycin results in decreased expression of COL3A1 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of COL3A1 protein]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]
Bleomycin results in increased expression of COL3A1 mRNA; Bleomycin results in increased expression of COL3A1 protein
CTD PMID:25933445 PMID:26817844 PMID:28726637 PMID:32032644 NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
JBrowse link
G Col5a1 collagen type V alpha 1 chain decreases expression EXP Bleomycin results in decreased expression of COL5A1 protein CTD PMID:25933445 NCBI chr 3:11,208,429...11,356,715
Ensembl chr 3:11,208,512...11,354,588
JBrowse link
G Comp cartilage oligomeric matrix protein multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein CTD PMID:29033951 NCBI chr16:19,047,206...19,055,584
Ensembl chr16:19,047,207...19,055,845
JBrowse link
G Cp ceruloplasmin multiple interactions
increases expression
ISO tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of CP protein] CTD PMID:12624602 NCBI chr 2:102,439,433...102,498,075
Ensembl chr 2:102,439,624...102,498,075
JBrowse link
G Crip2 cysteine-rich protein 2 affects expression EXP Bleomycin affects the expression of CRIP2 protein CTD PMID:25933445 NCBI chr 6:132,221,120...132,226,066
Ensembl chr 6:132,221,082...132,226,065
JBrowse link
G Csf2 colony stimulating factor 2 increases expression
decreases expression
ISO Bleomycin results in increased expression of CSF2 protein
Bleomycin results in decreased expression of CSF2 mRNA
CTD PMID:18684396 PMID:29720568 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199
JBrowse link
G Csf3 colony stimulating factor 3 decreases expression EXP Bleomycin results in decreased expression of CSF3 mRNA CTD PMID:15808516 NCBI chr10:83,660,787...83,664,569
Ensembl chr10:83,661,207...83,663,603
JBrowse link
G Csrp1 cysteine and glycine-rich protein 1 increases expression EXP Bleomycin results in increased expression of CSRP1 protein CTD PMID:25933445 NCBI chr13:47,158,171...47,179,388
Ensembl chr13:47,167,789...47,179,384
JBrowse link
G Ctsa cathepsin A affects expression ISO Bleomycin affects the expression of CTSA mRNA CTD PMID:26345256 NCBI chr 3:153,569,106...153,574,983
Ensembl chr 3:153,568,381...153,576,215
JBrowse link
G Ctsb cathepsin B affects expression ISO Bleomycin affects the expression of CTSB mRNA CTD PMID:26345256 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Ctsh cathepsin H affects expression ISO Bleomycin affects the expression of CTSH mRNA CTD PMID:26345256 NCBI chr 8:90,608,941...90,627,824
Ensembl chr 8:90,608,941...90,627,824
JBrowse link
G Ctss cathepsin S increases expression ISO Bleomycin results in increased expression of CTSS mRNA CTD PMID:19101991 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl10 C-X-C motif chemokine ligand 10 increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of CXCL10 mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL10 protein
Bleomycin results in decreased expression of CXCL10 mRNA
CTD PMID:26345256 PMID:29720568 PMID:33516805 NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO Bleomycin results in increased expression of CXCL12 mRNA CTD PMID:29720568 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 affects expression ISO Bleomycin affects the expression of CXCL13 mRNA CTD PMID:26345256 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933
JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression
multiple interactions
increases secretion
ISO
EXP
Bleomycin results in increased expression of CXCL2 protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of CXCL2 protein
3-aminobenzamide inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of CXCL2 mRNA]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]
CTD PMID:18684396 PMID:22687607 PMID:26520185 PMID:26600069 PMID:33516805 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
JBrowse link
G Cxcl3 C-X-C motif chemokine ligand 3 multiple interactions
increases secretion
ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein] CTD PMID:26600069 NCBI chr14:17,270,146...17,289,458
Ensembl chr14:17,270,146...17,289,511
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO Bleomycin results in increased expression of CXCL9 protein CTD PMID:29175452 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cycs cytochrome c, somatic affects localization EXP Bleomycin affects the localization of CYCS protein CTD PMID:15371238 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Dbi diazepam binding inhibitor, acyl-CoA binding protein increases expression EXP Bleomycin results in increased expression of DBI protein CTD PMID:25933445 NCBI chr13:31,241,466...31,249,853
Ensembl chr13:31,206,988...31,268,693
JBrowse link
G Des desmin increases expression EXP Bleomycin results in increased expression of DES protein CTD PMID:25933445 NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
JBrowse link
G Dlat dihydrolipoamide S-acetyltransferase decreases expression ISO Bleomycin results in decreased expression of DLAT protein CTD PMID:29733421 NCBI chr 8:50,979,151...51,004,435
Ensembl chr 8:50,978,051...51,004,479
JBrowse link
G Dld dihydrolipoamide dehydrogenase increases expression EXP
ISO
Bleomycin results in increased expression of DLD protein CTD PMID:25933445 PMID:29733421 NCBI chr 6:47,904,153...47,924,814
Ensembl chr 6:47,903,914...47,924,795
JBrowse link
G Dlk1 delta like non-canonical Notch ligand 1 increases expression ISO Bleomycin results in increased expression of DLK1 protein CTD PMID:29175452 NCBI chr 6:128,410,216...128,417,518
Ensembl chr 6:128,410,316...128,417,522
JBrowse link
G Dnmt1 DNA methyltransferase 1 affects response to substance ISO DNMT1 protein affects the susceptibility to Bleomycin CTD PMID:17991895 NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659
JBrowse link
G Dpep1 dipeptidase 1 decreases expression EXP Bleomycin results in decreased expression of DPEP1 protein CTD PMID:25933445 NCBI chr19:51,209,831...51,237,004
Ensembl chr19:51,219,660...51,235,257
JBrowse link
G Ech1 enoyl-CoA hydratase 1 decreases expression EXP Bleomycin results in decreased expression of ECH1 protein CTD PMID:25933445 NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
JBrowse link
G Edn1 endothelin 1 multiple interactions
increases expression
EXP Phytochemicals inhibits the reaction [Bleomycin results in increased expression of EDN1 mRNA] CTD PMID:26093215 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eef1a1 eukaryotic translation elongation factor 1 alpha 1 increases expression ISO Bleomycin results in increased expression of EEF1A1 protein CTD PMID:29733421 NCBI chr 8:79,341,554...79,344,784
Ensembl chr 8:79,341,557...79,344,839
JBrowse link
G Egr1 early growth response 1 increases expression
affects expression
multiple interactions
ISO Bleomycin results in increased expression of EGR1 mRNA
Bleomycin affects the expression of EGR1 mRNA
rosiglitazone inhibits the reaction [Bleomycin results in increased expression of EGR1 mRNA]
CTD PMID:19147827 PMID:26345256 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766
JBrowse link
G Egr2 early growth response 2 affects expression ISO Bleomycin affects the expression of EGR2 mRNA CTD PMID:26345256 NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562
JBrowse link
G Ehd1 EH-domain containing 1 decreases expression EXP Bleomycin results in decreased expression of EHD1 protein CTD PMID:25933445 NCBI chr 1:203,579,850...203,602,226
Ensembl chr 1:203,579,869...203,602,212
JBrowse link
G Ehd2 EH-domain containing 2 decreases expression EXP Bleomycin results in decreased expression of EHD2 protein CTD PMID:25933445 NCBI chr 1:76,639,568...76,658,747
Ensembl chr 1:76,637,482...76,658,783
JBrowse link
G Eif5a eukaryotic translation initiation factor 5A increases expression EXP Bleomycin results in increased expression of EIF5A protein CTD PMID:25933445 NCBI chr10:54,640,104...54,644,845
Ensembl chr10:54,640,024...54,644,656
JBrowse link
G Eln elastin increases expression ISO Bleomycin results in increased expression of ELN mRNA CTD PMID:26817844 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928
JBrowse link
G Epx eosinophil peroxidase increases expression EXP Bleomycin results in increased expression of EPX protein CTD PMID:26093215 NCBI chr10:72,666,865...72,677,952
Ensembl chr10:72,666,865...72,677,952
JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 decreases expression ISO Bleomycin results in decreased expression of ERRFI1 mRNA CTD PMID:33770205 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS1 mRNA CTD PMID:28726637 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Ets2 ETS proto-oncogene 2, transcription factor decreases expression ISO Bleomycin results in decreased expression of ETS2 mRNA CTD PMID:28726637 NCBI chr11:35,021,536...35,038,322
Ensembl chr11:35,021,596...35,038,319
JBrowse link
G Ezr ezrin decreases expression EXP Bleomycin results in decreased expression of EZR protein CTD PMID:25933445 NCBI chr 1:46,967,961...47,011,505
Ensembl chr 1:46,967,658...47,011,505
JBrowse link
G F2rl1 F2R like trypsin receptor 1 multiple interactions
increases expression
EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 mRNA]; allyl sulfide inhibits the reaction [Bleomycin results in increased expression of F2RL1 protein]
Bleomycin results in increased expression of F2RL1 mRNA; Bleomycin results in increased expression of F2RL1 protein
CTD PMID:23656969 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO Bleomycin results in decreased expression of FABP4 mRNA CTD PMID:29408570 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Faslg Fas ligand increases expression ISO Bleomycin results in increased expression of FASLG mRNA CTD PMID:11350791 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fgf2 fibroblast growth factor 2 increases expression
multiple interactions
EXP Bleomycin results in increased expression of FGF2 protein
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of FGF2 protein]
CTD PMID:25582705 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Fhl1 four and a half LIM domains 1 increases expression EXP Bleomycin results in increased expression of FHL1 protein CTD PMID:25933445 NCBI chr  X:134,555,399...134,614,930
Ensembl chr  X:134,555,479...134,614,928
JBrowse link
G Fn1 fibronectin 1 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of FN1 protein
Bleomycin results in increased expression of FN1 mRNA; Bleomycin results in increased expression of FN1 protein
[Bleomycin co-treated with Soot] results in increased expression of FN1 protein; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of FN1 protein]; Soot promotes the reaction [Bleomycin results in increased expression of FN1 mRNA]
CTD PMID:25071917 PMID:25933445 PMID:26345256 PMID:26817844 PMID:28300665 More... NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of FOS protein CTD PMID:12003776 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Foxp3 forkhead box P3 increases expression ISO Bleomycin results in increased expression of FOXP3 mRNA CTD PMID:29033951 NCBI chr  X:14,908,494...14,924,994
Ensembl chr  X:14,908,494...14,923,838
JBrowse link
G Fshr follicle stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of FSHR mRNA CTD PMID:15808516 NCBI chr 6:5,198,825...5,406,785
Ensembl chr 6:5,198,825...5,406,785
JBrowse link
G Fubp1 far upstream element binding protein 1 increases expression EXP Bleomycin results in increased expression of FUBP1 protein CTD PMID:25933445 NCBI chr 2:241,159,481...241,186,591
Ensembl chr 2:241,159,512...241,186,602
JBrowse link
G Fzd6 frizzled class receptor 6 increases expression
multiple interactions
ISO Bleomycin results in increased expression of FZD6 mRNA
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]
CTD PMID:28726637 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 decreases expression EXP Bleomycin results in decreased expression of GABRA4 mRNA CTD PMID:15808516 NCBI chr14:36,590,782...36,667,724
Ensembl chr14:36,590,782...36,665,844
JBrowse link
G Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 decreases expression EXP Bleomycin results in decreased expression of GABRB2 mRNA CTD PMID:15808516 NCBI chr10:26,936,592...27,156,141
Ensembl chr10:26,936,551...27,151,251
JBrowse link
G Gabrg2 gamma-aminobutyric acid type A receptor subunit gamma 2 decreases expression EXP Bleomycin results in decreased expression of GABRG2 mRNA CTD PMID:15808516 NCBI chr10:26,376,805...26,463,680
Ensembl chr10:26,374,694...26,464,346
JBrowse link
G Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 decreases expression EXP Bleomycin results in decreased expression of GABRR1 mRNA CTD PMID:15808516 NCBI chr 5:47,524,151...47,561,228
Ensembl chr 5:47,524,151...47,561,228
JBrowse link
G Ganab glucosidase II alpha subunit multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of GANAB protein CTD PMID:29733421 NCBI chr 1:205,793,810...205,813,701
Ensembl chr 1:205,793,895...205,813,695
JBrowse link
G Gas6 growth arrest specific 6 increases expression ISO Bleomycin results in increased expression of GAS6 protein CTD PMID:29175452 NCBI chr16:76,045,430...76,075,904
Ensembl chr16:76,045,426...76,075,904
JBrowse link
G Gata3 GATA binding protein 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of GATA3 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]
CTD PMID:29033951 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391
JBrowse link
G Gc GC, vitamin D binding protein increases expression EXP Bleomycin results in increased expression of GC protein CTD PMID:25933445 NCBI chr14:18,632,146...18,667,563
Ensembl chr14:18,632,135...18,667,567
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit multiple interactions
decreases expression
ISO caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of GCLC protein] CTD PMID:23570914 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gda guanine deaminase decreases expression EXP Bleomycin results in decreased expression of GDA protein CTD PMID:25933445 NCBI chr 1:218,903,045...218,982,360
Ensembl chr 1:218,906,815...218,982,416
JBrowse link
G Gpi glucose-6-phosphate isomerase decreases expression EXP Bleomycin results in decreased expression of GPI protein CTD PMID:25933445 NCBI chr 1:86,828,211...86,856,077
Ensembl chr 1:86,828,216...86,856,086
JBrowse link
G Gpx1 glutathione peroxidase 1 affects expression EXP Bleomycin affects the expression of GPX1 protein CTD PMID:25933445 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gria2 glutamate ionotropic receptor AMPA type subunit 2 decreases expression EXP Bleomycin results in decreased expression of GRIA2 mRNA CTD PMID:15808516 NCBI chr 2:165,949,379...166,069,510
Ensembl chr 2:165,947,521...166,069,510
JBrowse link
G Grik3 glutamate ionotropic receptor kainate type subunit 3 decreases expression EXP Bleomycin results in decreased expression of GRIK3 mRNA CTD PMID:15808516 NCBI chr 5:137,767,865...137,989,617
Ensembl chr 5:137,767,865...137,984,307
JBrowse link
G Grpr gastrin releasing peptide receptor decreases expression EXP Bleomycin results in decreased expression of GRPR mRNA CTD PMID:15808516 NCBI chr  X:30,998,425...31,038,442
Ensembl chr  X:30,998,416...31,038,442
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta multiple interactions
increases phosphorylation
ISO [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in decreased phosphorylation of GSK3B protein] which results in decreased susceptibility to Bleomycin; [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
JBrowse link
G Gsn gelsolin decreases expression EXP Bleomycin results in decreased expression of GSN protein CTD PMID:25933445 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402
JBrowse link
G Gsr glutathione-disulfide reductase decreases activity
multiple interactions
EXP Bleomycin results in decreased activity of GSR protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of GSR protein]
CTD PMID:26768587 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm1 glutathione S-transferase mu 1 decreases expression EXP Bleomycin results in decreased expression of GSTM1 protein CTD PMID:25933445 NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411
JBrowse link
G H1f0 H1.0 linker histone affects expression EXP Bleomycin affects the expression of H1F0 protein CTD PMID:25933445 NCBI chr 7:110,592,834...110,594,694
Ensembl chr 7:110,592,208...110,594,694
JBrowse link
G H1f4 H1.4 linker histone, cluster member affects expression EXP Bleomycin affects the expression of H1F4 protein CTD PMID:25933445 NCBI chr17:41,486,634...41,487,293
Ensembl chr17:41,486,560...41,487,403
JBrowse link
G H2ax H2A.X variant histone increases expression ISO Bleomycin results in increased expression of H2AX protein CTD PMID:25130544 NCBI chr 8:44,671,927...44,673,257
Ensembl chr 8:44,671,786...44,673,239
JBrowse link
G Hadha hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha decreases expression EXP Bleomycin results in decreased expression of HADHA protein CTD PMID:25933445 NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
JBrowse link
G Havcr1 hepatitis A virus cellular receptor 1 increases expression ISO Bleomycin results in increased expression of HAVCR1 protein CTD PMID:29175452 NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
JBrowse link
G Hbb hemoglobin subunit beta affects expression EXP Bleomycin affects the expression of HBB protein CTD PMID:25933445 NCBI chr 1:158,250,421...158,251,832 JBrowse link
G Hbegf heparin-binding EGF-like growth factor increases expression ISO Bleomycin results in increased expression of HBEGF mRNA CTD PMID:18684396 NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441
JBrowse link
G Hgf hepatocyte growth factor decreases expression
multiple interactions
increases expression
increases secretion
EXP
ISO
Bleomycin results in decreased expression of HGF mRNA; Bleomycin results in decreased expression of HGF protein
Berberine inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]
Bleomycin results in increased expression of HGF mRNA
Bleomycin results in increased secretion of HGF protein
Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF mRNA]; Valsartan inhibits the reaction [Bleomycin results in decreased expression of HGF protein]
CTD PMID:16115399 PMID:22687607 PMID:29408570 NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409
JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha multiple interactions
increases expression
ISO [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of HIF1A mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
JBrowse link
G Hist1h2bg histone cluster 1, H2bg decreases expression EXP Bleomycin results in decreased expression of HIST1H2BG protein CTD PMID:25933445 NCBI chr17:41,571,278...41,571,658
Ensembl chr17:41,571,210...41,571,896
JBrowse link
G Hmces 5-hydroxymethylcytosine binding, ES cell specific decreases expression ISO Bleomycin results in decreased expression of HMCES mRNA CTD PMID:33770205 NCBI chr 4:120,392,812...120,415,616 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
increases expression
EXP
ISO
protocatechualdehyde inhibits the reaction [Bleomycin results in increased expression of HMGB1 protein]
Bleomycin inhibits the reaction [Azacitidine results in decreased expression of and results in increased secretion of HMGB1 protein]; Bleomycin inhibits the reaction [Azacitidine results in decreased expression of HMGB1 mRNA]
CTD PMID:25582705 PMID:32278510 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of HMOX1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of HMOX1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of HMOX1 mRNA]
PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]
CTD PMID:16317386 PMID:26093215 PMID:26768587 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hnrnpa2b1 heterogeneous nuclear ribonucleoprotein A2/B1 increases expression EXP Bleomycin results in increased expression of HNRNPA2B1 protein CTD PMID:25933445 NCBI chr 4:80,534,659...80,545,297
Ensembl chr 4:80,534,651...80,545,249
JBrowse link
G Hnrnpa3 heterogeneous nuclear ribonucleoprotein A3 increases expression EXP Bleomycin results in increased expression of HNRNPA3 protein CTD PMID:25933445 NCBI chr 3:60,578,574...60,588,755
Ensembl chr 3:60,578,673...60,588,306
JBrowse link
G Hpx hemopexin increases expression EXP Bleomycin results in increased expression of HPX protein CTD PMID:25933445 NCBI chr 1:159,932,819...159,940,327
Ensembl chr 1:159,932,755...159,940,328
JBrowse link
G Hsp90aa1 heat shock protein 90 alpha family class A member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90AA1 protein CTD PMID:24478030 NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
JBrowse link
G Hsp90b1 heat shock protein 90 beta family member 1 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of HSP90B1 protein CTD PMID:24478030 NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 increases expression EXP Bleomycin results in increased expression of HSPA5 protein CTD PMID:25933445 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Hspb1 heat shock protein family B (small) member 1 decreases expression EXP Bleomycin results in decreased expression of HSPB1 protein CTD PMID:25933445 NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
JBrowse link
G Hspe1 heat shock protein family E (Hsp10) member 1 increases expression EXP
ISO
Bleomycin results in increased expression of HSPE1 protein CTD PMID:25933445 PMID:29733421 NCBI chr 9:56,589,912...56,593,000
Ensembl chr 9:56,589,789...56,593,089
JBrowse link
G Htr1f 5-hydroxytryptamine receptor 1F decreases expression EXP Bleomycin results in decreased expression of HTR1F mRNA CTD PMID:15808516 NCBI chr11:2,642,751...2,644,150
Ensembl chr11:2,642,751...2,644,150
JBrowse link
G Htr5a 5-hydroxytryptamine receptor 5A decreases expression EXP Bleomycin results in decreased expression of HTR5A mRNA CTD PMID:15808516 NCBI chr 4:7,444,968...7,454,651
Ensembl chr 4:7,444,968...7,454,651
JBrowse link
G Htr5b 5-hydroxytryptamine (serotonin) receptor 5B decreases expression EXP Bleomycin results in decreased expression of HTR5B mRNA CTD PMID:15808516 NCBI chr13:32,686,911...32,699,835
Ensembl chr13:32,687,042...32,699,835
JBrowse link
G Icam1 intercellular adhesion molecule 1 increases expression ISO Bleomycin results in increased expression of ICAM1 mRNA CTD PMID:29033951 PMID:29720568 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Idh2 isocitrate dehydrogenase (NADP(+)) 2 decreases expression EXP Bleomycin results in decreased expression of IDH2 protein CTD PMID:25933445 NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025
JBrowse link
G Ifng interferon gamma increases expression
multiple interactions
decreases expression
ISO
EXP
Bleomycin results in increased expression of IFNG mRNA
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG protein
[SPL-334 co-treated with Bleomycin] results in increased expression of IFNG protein
Bleomycin results in decreased expression of IFNG mRNA
CTD PMID:11350791 PMID:25071917 PMID:26209236 PMID:29408570 PMID:33516805 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 increases expression ISO Bleomycin results in increased expression of IGF1 mRNA CTD PMID:1705203 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il10 interleukin 10 increases expression ISO Bleomycin results in increased expression of IL10 protein CTD PMID:29175452 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il12b interleukin 12B increases expression ISO Bleomycin results in increased expression of IL12B mRNA; Bleomycin results in increased expression of IL12B protein CTD PMID:11350791 NCBI chr10:28,888,832...28,903,796
Ensembl chr10:28,893,008...28,902,903
JBrowse link
G Il12rb2 interleukin 12 receptor subunit beta 2 increases expression ISO Bleomycin results in increased expression of IL12RB2 mRNA CTD PMID:11350791 NCBI chr 4:96,424,615...96,515,327
Ensembl chr 4:96,426,842...96,515,289
JBrowse link
G Il13 interleukin 13 decreases response to substance
multiple interactions
ISO IL13 gene mutant form results in decreased susceptibility to Bleomycin
IL13 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
CTD PMID:15322207 NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
JBrowse link
G Il1a interleukin 1 alpha multiple interactions
increases expression
ISO IL1A protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1A protein
CTD PMID:8317554 PMID:29175452 NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
JBrowse link
G Il1b interleukin 1 beta multiple interactions
increases secretion
affects expression
increases expression
ISO
EXP
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of IL1B protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
Bleomycin affects the expression of IL1B mRNA
IL1B protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
Bleomycin results in increased expression of IL1B mRNA; Bleomycin results in increased expression of IL1B protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL1B mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of IL1B protein]
CTD PMID:8317554 PMID:8473757 PMID:16317386 PMID:17035056 PMID:17118201 More... NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il2 interleukin 2 multiple interactions EXP [Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of IL2 protein CTD PMID:33516805 NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
JBrowse link
G Il4 interleukin 4 increases expression
affects response to substance
multiple interactions
decreases response to substance
ISO Bleomycin results in increased expression of IL4 mRNA
IL4 protein affects the susceptibility to Bleomycin
IL4 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
IL4 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:11554783 PMID:12574379 PMID:15322207 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of IL6 protein
Calcitriol inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
Bleomycin results in increased expression of IL6 mRNA; Bleomycin results in increased expression of IL6 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of IL6 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of IL6 mRNA]; resveratrol inhibits the reaction [Bleomycin results in increased expression of IL6 protein]
CTD PMID:17035056 PMID:18684396 PMID:23656969 PMID:25071917 PMID:26093215 More... NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jpt1 Jupiter microtubule associated homolog 1 increases expression EXP Bleomycin results in increased expression of JPT1 protein CTD PMID:25933445 NCBI chr10:100,744,468...100,762,504
Ensembl chr10:100,686,797...100,784,513
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases activity ISO Bleomycin results in increased activity of JUN protein CTD PMID:12003776 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 decreases expression
multiple interactions
EXP Bleomycin results in decreased expression of KEAP1 protein
celastrol inhibits the reaction [Bleomycin results in decreased expression of KEAP1 protein]
CTD PMID:26768587 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Khsrp KH-type splicing regulatory protein increases expression EXP Bleomycin results in increased expression of KHSRP protein CTD PMID:25933445 NCBI chr 9:1,862,555...1,872,301
Ensembl chr 9:1,862,899...1,872,451
JBrowse link
G Kit KIT proto-oncogene receptor tyrosine kinase increases expression
multiple interactions
ISO Bleomycin results in increased expression of KIT protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in increased expression of KIT protein
CTD PMID:29733421 NCBI chr14:32,547,459...32,624,694
Ensembl chr14:32,548,877...32,624,652
JBrowse link
G Kl Klotho decreases expression ISO Bleomycin results in decreased expression of KL mRNA CTD PMID:29408570 NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080
JBrowse link
G Klhl42 kelch-like family, member 42 increases expression ISO Bleomycin results in increased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283
JBrowse link
G Kras KRAS proto-oncogene, GTPase multiple interactions ISO [Bleomycin co-treated with 1-nitropyrene] results in increased mutagenesis of KRAS gene CTD PMID:12616606 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Krt19 keratin 19 decreases expression EXP Bleomycin results in decreased expression of KRT19 protein CTD PMID:25933445 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Lap3 leucine aminopeptidase 3 increases expression EXP Bleomycin results in increased expression of LAP3 protein CTD PMID:25933445 NCBI chr14:65,608,375...65,627,359
Ensembl chr14:65,608,376...65,627,359
JBrowse link
G Lasp1 LIM and SH3 protein 1 increases expression EXP Bleomycin results in increased expression of LASP1 protein CTD PMID:25933445 NCBI chr10:82,795,177...82,835,659
Ensembl chr10:82,795,137...82,943,292
JBrowse link
G Lcn2 lipocalin 2 increases expression ISO Bleomycin results in increased expression of LCN2 mRNA; Bleomycin results in increased expression of LCN2 protein CTD PMID:26345256 NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
JBrowse link
G Lep leptin increases expression ISO Bleomycin results in increased expression of LEP protein CTD PMID:29175452 NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
JBrowse link
G Lgals3 galectin 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of LGALS3 protein
NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]
CTD PMID:26526764 NCBI chr15:20,620,083...20,632,019
Ensembl chr15:20,607,692...20,632,025
JBrowse link
G Lhx1 LIM homeobox 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of LHX1 mRNA CTD PMID:29733421 NCBI chr10:69,396,829...69,403,617
Ensembl chr10:69,396,829...69,403,617
JBrowse link
G Liph lipase H decreases expression ISO Bleomycin results in decreased expression of LIPH mRNA CTD PMID:33770205 NCBI chr11:79,032,229...79,081,625 JBrowse link
G Lmna lamin A/C increases expression EXP Bleomycin results in increased expression of LMNA protein CTD PMID:25933445 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423
JBrowse link
G Lyz2 lysozyme 2 decreases expression EXP Bleomycin results in decreased expression of LYZ protein CTD PMID:25933445 NCBI chr 7:52,906,810...52,912,154
Ensembl chr 7:52,906,811...52,912,106
JBrowse link
G Macroh2a1 macroH2A.1 histone decreases expression EXP Bleomycin results in decreased expression of MACROH2A1 protein CTD PMID:25933445 NCBI chr17:8,479,331...8,542,071
Ensembl chr17:8,479,372...8,542,072
JBrowse link
G Map1lc3b microtubule-associated protein 1 light chain 3 beta increases expression
multiple interactions
ISO Bleomycin results in increased expression of MAP1LC3B protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of MAP1LC3B protein modified form]
CTD PMID:31302203 NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK1 protein] CTD PMID:23570914 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of and results in increased activity of MAPK3 protein] CTD PMID:23570914 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Marcks myristoylated alanine rich protein kinase C substrate decreases expression EXP Bleomycin results in decreased expression of MARCKS protein CTD PMID:25933445 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012
JBrowse link
G Mdh2 malate dehydrogenase 2 decreases expression
multiple interactions
EXP
ISO
Bleomycin results in decreased expression of MDH2 protein
[Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of MDH2 protein
CTD PMID:25933445 PMID:29733421 NCBI chr12:20,894,269...20,907,225
Ensembl chr12:20,894,262...20,907,271
JBrowse link
G Mecp2 methyl CpG binding protein 2 affects response to substance ISO MECP2 protein affects the susceptibility to Bleomycin CTD PMID:21435439 NCBI chr  X:151,781,177...151,844,687
Ensembl chr  X:151,789,930...151,844,689
JBrowse link
G Mepce methylphosphate capping enzyme increases expression ISO Bleomycin results in increased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:18,911,796...18,916,515
Ensembl chr12:18,911,796...18,916,514
JBrowse link
G Mertk MER proto-oncogene, tyrosine kinase multiple interactions
increases phosphorylation
ISO Bleomycin affects the localization of and affects the expression of MERTK protein
Bleomycin results in increased phosphorylation of MERTK protein
CTD PMID:22687607 NCBI chr 3:115,939,351...116,045,141
Ensembl chr 3:115,939,351...116,046,554
JBrowse link
G Mif macrophage migration inhibitory factor decreases expression EXP Bleomycin results in decreased expression of MIF protein CTD PMID:25933445 NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
JBrowse link
G Mir100 microRNA 100 decreases expression EXP Bleomycin results in decreased expression of MIR100 mRNA CTD PMID:25933445 NCBI chr 8:41,901,225...41,901,304
Ensembl chr 8:41,901,225...41,901,304
JBrowse link
G Mir101-2 microRNA 101-2 decreases expression EXP
ISO
Bleomycin results in decreased expression of MIR101B mRNA CTD PMID:25933445 PMID:28726637 NCBI chr 1:226,860,371...226,860,467
Ensembl chr 1:226,860,371...226,860,467
JBrowse link
G Mir101a microRNA 101a multiple interactions
decreases expression
ISO
EXP
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of COL3A1 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of FZD6 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA]; MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
Bleomycin results in decreased expression of MIR101A mRNA
CTD PMID:25933445 PMID:28726637 NCBI chr 5:115,966,332...115,966,406
Ensembl chr 5:115,966,328...115,966,410
JBrowse link
G Mir106b microRNA 106b affects expression EXP Bleomycin affects the expression of MIR106B mRNA CTD PMID:25933445 NCBI chr12:17,043,344...17,043,425
Ensembl chr12:17,043,344...17,043,425
JBrowse link
G Mir107 microRNA 107 decreases expression EXP Bleomycin results in decreased expression of MIR107 mRNA CTD PMID:25933445 NCBI chr 1:232,337,767...232,337,853
Ensembl chr 1:232,337,767...232,337,853
JBrowse link
G Mir10a microRNA 10a decreases expression EXP Bleomycin results in decreased expression of MIR10A mRNA CTD PMID:25933445 NCBI chr10:81,283,171...81,283,280
Ensembl chr10:81,283,171...81,283,280
JBrowse link
G Mir10b microRNA 10b decreases expression EXP Bleomycin results in decreased expression of MIR10B mRNA CTD PMID:25933445 NCBI chr 3:59,628,438...59,628,546
Ensembl chr 3:59,628,438...59,628,546
JBrowse link
G Mir1224 microRNA 1224 increases expression EXP Bleomycin results in increased expression of MIR1224 mRNA CTD PMID:25933445 NCBI chr11:80,306,902...80,306,986
Ensembl chr11:80,306,902...80,306,986
JBrowse link
G Mir1249 microRNA 1249 affects expression EXP Bleomycin affects the expression of MIR1249 mRNA CTD PMID:25933445 NCBI chr 7:116,075,593...116,075,712
Ensembl chr 7:116,075,593...116,075,712
JBrowse link
G Mir125a microRNA 125a affects expression EXP Bleomycin affects the expression of MIR125A mRNA CTD PMID:25933445 NCBI chr 1:58,677,626...58,677,710
Ensembl chr 1:58,677,626...58,677,710
JBrowse link
G Mir126b microRNA 126b decreases expression EXP Bleomycin results in decreased expression of MIR126 mRNA CTD PMID:25933445 NCBI chr 3:9,415,087...9,415,159 JBrowse link
G Mir130a microRNA 130a decreases expression EXP Bleomycin results in decreased expression of MIR130A mRNA CTD PMID:25933445 NCBI chr 3:69,822,542...69,822,629
Ensembl chr 3:69,822,542...69,822,629
JBrowse link
G Mir133a1 microRNA 133a-1 decreases expression EXP Bleomycin results in decreased expression of MIR133A1 mRNA CTD PMID:25933445 NCBI chr18:1,885,082...1,885,168 JBrowse link
G Mir133b microRNA 133b decreases expression EXP Bleomycin results in decreased expression of MIR133B mRNA CTD PMID:25933445 NCBI chr 9:23,098,134...23,098,217
Ensembl chr 9:23,098,134...23,098,217
JBrowse link
G Mir140 microRNA 140 affects expression EXP Bleomycin affects the expression of MIR140 mRNA CTD PMID:25933445 NCBI chr19:35,465,577...35,465,675
Ensembl chr19:35,465,577...35,465,675
JBrowse link
G Mir141 microRNA 141 affects expression EXP Bleomycin affects the expression of MIR141 mRNA CTD PMID:25933445 NCBI chr 4:157,523,239...157,523,332
Ensembl chr 4:157,523,239...157,523,332
JBrowse link
G Mir142 microRNA 142 decreases expression
increases expression
EXP Bleomycin results in decreased expression of MIR142 mRNA
Bleomycin results in increased expression of MIR142 mRNA
CTD PMID:25933445 NCBI chr10:72,557,864...72,557,950
Ensembl chr10:72,557,857...72,557,967
JBrowse link
G Mir143 microRNA 143 decreases expression EXP Bleomycin results in decreased expression of MIR143 mRNA CTD PMID:25933445 NCBI chr18:55,101,006...55,101,110
Ensembl chr18:55,101,006...55,101,110
JBrowse link
G Mir144 microRNA 144 decreases expression EXP Bleomycin results in decreased expression of MIR144 mRNA CTD PMID:25933445 NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430
JBrowse link
G Mir145 microRNA 145 decreases expression EXP Bleomycin results in decreased expression of MIR145 mRNA CTD PMID:25933445 NCBI chr18:55,099,640...55,099,727
Ensembl chr18:55,099,640...55,099,727
JBrowse link
G Mir146a microRNA 146a affects expression EXP Bleomycin affects the expression of MIR146A mRNA CTD PMID:25933445 NCBI chr10:27,848,516...27,848,610
Ensembl chr10:27,848,516...27,848,610
JBrowse link
G Mir146b microRNA 146b increases expression EXP Bleomycin results in increased expression of MIR146B mRNA CTD PMID:25933445 NCBI chr 1:245,203,438...245,203,525
Ensembl chr 1:245,203,438...245,203,525
JBrowse link
G Mir148b microRNA 148b decreases expression EXP Bleomycin results in decreased expression of MIR148B mRNA CTD PMID:25933445 NCBI chr 7:134,421,398...134,421,494
Ensembl chr 7:134,421,398...134,421,494
JBrowse link
G Mir150 microRNA 150 affects expression EXP Bleomycin affects the expression of MIR150 mRNA CTD PMID:25933445 NCBI chr 1:95,605,024...95,605,108
Ensembl chr 1:95,605,024...95,605,108
JBrowse link
G Mir151 microRNA 151 decreases expression EXP Bleomycin results in decreased expression of MIR151 mRNA CTD PMID:25933445 NCBI chr 7:105,172,377...105,172,473 JBrowse link
G Mir152 microRNA 152 decreases expression EXP Bleomycin results in decreased expression of MIR152 mRNA CTD PMID:25933445 NCBI chr10:81,832,936...81,833,020
Ensembl chr10:81,832,936...81,833,020
JBrowse link
G Mir15b microRNA 15b affects expression EXP Bleomycin affects the expression of MIR15B mRNA CTD PMID:25933445 NCBI chr 2:153,245,200...153,245,297
Ensembl chr 2:153,245,200...153,245,297
JBrowse link
G Mir16 microRNA 16 decreases expression EXP Bleomycin results in decreased expression of MIR16 mRNA CTD PMID:25933445 NCBI chr 2:153,245,349...153,245,443
Ensembl chr 2:153,245,349...153,245,443
JBrowse link
G Mir17 microRNA 17 affects expression EXP Bleomycin affects the expression of MIR17 mRNA CTD PMID:25933445 NCBI chr15:92,180,629...92,180,712
Ensembl chr15:92,180,629...92,180,712
JBrowse link
G Mir181c microRNA 181c decreases expression EXP Bleomycin results in decreased expression of MIR181C mRNA CTD PMID:25933445 NCBI chr19:23,983,523...23,983,628
Ensembl chr19:23,983,523...23,983,628
JBrowse link
G Mir181d microRNA 181d decreases expression EXP Bleomycin results in decreased expression of MIR181D mRNA CTD PMID:25933445 NCBI chr19:23,983,706...23,983,788
Ensembl chr19:23,983,706...23,983,788
JBrowse link
G Mir183 microRNA 183 affects expression EXP Bleomycin affects the expression of MIR183 mRNA CTD PMID:25933445 NCBI chr 4:58,788,614...58,788,723
Ensembl chr 4:58,788,614...58,788,723
JBrowse link
G Mir185 microRNA 185 decreases expression EXP Bleomycin results in decreased expression of MIR185 mRNA CTD PMID:25933445 NCBI chr11:82,664,716...82,664,795
Ensembl chr11:82,664,716...82,664,795
JBrowse link
G Mir186 microRNA 186 decreases expression EXP Bleomycin results in decreased expression of MIR186 mRNA CTD PMID:25933445 NCBI chr 2:246,582,806...246,582,891
Ensembl chr 2:246,582,806...246,582,891
JBrowse link
G Mir188 microRNA 188 affects expression EXP Bleomycin affects the expression of MIR188 mRNA CTD PMID:25933445 NCBI chr  X:15,247,715...15,247,794
Ensembl chr  X:15,247,715...15,247,794
JBrowse link
G Mir18a microRNA 18a increases expression EXP Bleomycin results in increased expression of MIR18A mRNA CTD PMID:25933445 NCBI chr15:92,180,765...92,180,860
Ensembl chr15:92,180,765...92,180,860
JBrowse link
G Mir193 microRNA 193 decreases expression EXP Bleomycin results in decreased expression of MIR193 mRNA CTD PMID:25933445 NCBI chr10:64,672,354...64,672,439 JBrowse link
G Mir195 microRNA 195 decreases expression EXP Bleomycin results in decreased expression of MIR195 mRNA CTD PMID:25933445 NCBI chr10:54,951,838...54,951,924
Ensembl chr10:54,951,838...54,951,924
JBrowse link
G Mir199a2 microRNA 199a-2 affects expression EXP Bleomycin affects the expression of MIR199A2 mRNA CTD PMID:25933445 NCBI chr13:74,582,954...74,583,063
Ensembl chr13:74,582,954...74,583,063
JBrowse link
G Mir19a microRNA 19a affects expression EXP Bleomycin affects the expression of MIR19A mRNA CTD PMID:25933445 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993
JBrowse link
G Mir200a microRNA 200a decreases expression EXP Bleomycin results in decreased expression of MIR200A mRNA CTD PMID:25933445 NCBI chr 5:166,648,494...166,648,582 JBrowse link
G Mir200b microRNA 200b decreases expression EXP Bleomycin results in decreased expression of MIR200B mRNA CTD PMID:25933445 NCBI chr 5:166,649,272...166,649,366
Ensembl chr 5:166,649,272...166,649,366
JBrowse link
G Mir200c microRNA 200c decreases expression EXP Bleomycin results in decreased expression of MIR200C mRNA CTD PMID:25933445 NCBI chr 4:157,523,679...157,523,747 JBrowse link
G Mir204 microRNA 204 decreases expression EXP Bleomycin results in decreased expression of MIR204 mRNA CTD PMID:25933445 NCBI chr 1:220,316,931...220,317,040
Ensembl chr 1:220,316,931...220,317,040
JBrowse link
G Mir20a microRNA 20a affects expression EXP Bleomycin affects the expression of MIR20A mRNA CTD PMID:25933445 NCBI chr15:92,181,084...92,181,168
Ensembl chr15:92,181,084...92,181,168
JBrowse link
G Mir20b microRNA 20b affects expression EXP Bleomycin affects the expression of MIR20B mRNA CTD PMID:25933445 NCBI chr  X:132,422,211...132,422,282
Ensembl chr  X:132,422,211...132,422,282
JBrowse link
G Mir21 microRNA 21 increases expression EXP Bleomycin results in increased expression of MIR21 mRNA CTD PMID:25933445 NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348
JBrowse link
G Mir210 microRNA 210 decreases expression EXP Bleomycin results in decreased expression of MIR210 mRNA CTD PMID:25933445 NCBI chr 1:196,326,343...196,326,452 JBrowse link
G Mir211 microRNA 211 affects expression EXP Bleomycin affects the expression of MIR211 mRNA CTD PMID:25933445 NCBI chr 1:117,777,539...117,777,644
Ensembl chr 1:117,777,539...117,777,644
JBrowse link
G Mir212 microRNA 212 affects expression EXP Bleomycin affects the expression of MIR212 mRNA CTD PMID:25933445 NCBI chr10:60,023,403...60,023,513
Ensembl chr10:60,023,403...60,023,513
JBrowse link
G Mir22 microRNA 22 affects expression EXP Bleomycin affects the expression of MIR22 mRNA CTD PMID:25933445 NCBI chr10:60,307,039...60,307,133
Ensembl chr10:60,307,039...60,307,133
JBrowse link
G Mir221 microRNA 221 decreases expression EXP Bleomycin results in decreased expression of MIR221 mRNA CTD PMID:25933445 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573
JBrowse link
G Mir222 microRNA 222 decreases expression EXP Bleomycin results in decreased expression of MIR222 mRNA CTD PMID:25933445 NCBI chr  X:3,428,904...3,429,006
Ensembl chr  X:3,428,904...3,429,006
JBrowse link
G Mir223 microRNA 223 affects expression EXP Bleomycin affects the expression of MIR223 mRNA CTD PMID:25933445 NCBI chr  X:61,141,887...61,141,996
Ensembl chr  X:61,141,887...61,141,996
JBrowse link
G Mir23a microRNA 23a decreases expression EXP Bleomycin results in decreased expression of MIR23A mRNA CTD PMID:25933445 NCBI chr19:23,954,997...23,955,071
Ensembl chr19:23,954,997...23,955,071
JBrowse link
G Mir23b microRNA 23b decreases expression EXP Bleomycin results in decreased expression of MIR23B mRNA CTD PMID:25933445 NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763
JBrowse link
G Mir24-2 microRNA 24-2 decreases expression EXP Bleomycin results in decreased expression of MIR24-2 mRNA CTD PMID:25933445 NCBI chr19:23,954,683...23,954,790
Ensembl chr19:23,954,683...23,954,790
JBrowse link
G Mir25 microRNA 25 affects expression EXP Bleomycin affects the expression of MIR25 mRNA CTD PMID:25933445 NCBI chr12:17,042,932...17,043,015
Ensembl chr12:17,042,932...17,043,015
JBrowse link
G Mir26a microRNA 26a decreases expression EXP Bleomycin results in decreased expression of MIR26A mRNA CTD PMID:25933445 NCBI chr 8:118,755,289...118,755,378
Ensembl chr 8:118,755,289...118,755,378
JBrowse link
G Mir26b microRNA 26b decreases expression EXP Bleomycin results in decreased expression of MIR26B mRNA CTD PMID:25933445 NCBI chr 9:75,976,596...75,976,680
Ensembl chr 9:75,976,596...75,976,680
JBrowse link
G Mir27a microRNA 27a decreases expression EXP Bleomycin results in decreased expression of MIR27A mRNA CTD PMID:25933445 NCBI chr19:23,954,831...23,954,917
Ensembl chr19:23,954,831...23,954,917
JBrowse link
G Mir27b microRNA 27b decreases expression EXP Bleomycin results in decreased expression of MIR27B mRNA CTD PMID:25933445 NCBI chr17:1,813,427...1,813,523
Ensembl chr17:1,813,426...1,813,529
JBrowse link
G Mir28 microRNA 28 decreases expression EXP Bleomycin results in decreased expression of MIR28 mRNA CTD PMID:25933445 NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608
JBrowse link
G Mir290 microRNA 290 increases expression EXP Bleomycin results in increased expression of MIR290 mRNA CTD PMID:25933445 NCBI chr 1:65,964,648...65,964,728
Ensembl chr 1:65,964,648...65,964,728
JBrowse link
G Mir296 microRNA 296 affects expression EXP Bleomycin affects the expression of MIR296 mRNA CTD PMID:25933445 NCBI chr 3:163,051,838...163,051,915
Ensembl chr 3:163,051,838...163,051,915
JBrowse link
G Mir2985 microRNA 2985 affects expression EXP Bleomycin affects the expression of MIR2985 mRNA CTD PMID:25933445 NCBI chr 2:165,956,389...165,956,498
Ensembl chr 2:165,956,389...165,956,498
JBrowse link
G Mir29a microRNA 29a decreases expression EXP Bleomycin results in decreased expression of MIR29A mRNA CTD PMID:25933445 NCBI chr 4:59,650,608...59,650,695 JBrowse link
G Mir301a microRNA 301a affects expression EXP Bleomycin affects the expression of MIR301A mRNA CTD PMID:25933445 NCBI chr10:71,925,336...71,925,435
Ensembl chr10:71,925,336...71,925,435
JBrowse link
G Mir30a microRNA 30a decreases expression EXP Bleomycin results in decreased expression of MIR30A mRNA CTD PMID:25933445 NCBI chr 9:25,737,600...25,737,670
Ensembl chr 9:25,737,600...25,737,670
JBrowse link
G Mir30b microRNA 30b decreases expression EXP Bleomycin results in decreased expression of MIR30B mRNA CTD PMID:25933445 NCBI chr 7:100,132,589...100,132,675
Ensembl chr 7:100,132,589...100,132,675
JBrowse link
G Mir30c2 microRNA 30c-2 decreases expression EXP Bleomycin results in decreased expression of MIR30C2 mRNA CTD PMID:25933445 NCBI chr 9:25,757,342...25,757,425
Ensembl chr 9:25,757,342...25,757,425
JBrowse link
G Mir30d microRNA 30d decreases expression EXP Bleomycin results in decreased expression of MIR30D mRNA CTD PMID:25933445 NCBI chr 7:100,136,391...100,136,472
Ensembl chr 7:100,136,391...100,136,472
JBrowse link
G Mir30e microRNA 30e decreases expression EXP Bleomycin results in decreased expression of MIR30E mRNA CTD PMID:25933445 NCBI chr 5:134,352,232...134,352,323
Ensembl chr 5:134,352,232...134,352,323
JBrowse link
G Mir31 microRNA 31 decreases expression EXP Bleomycin results in decreased expression of MIR31 mRNA CTD PMID:25933445 NCBI chr 5:103,599,038...103,599,143 JBrowse link
G Mir32 microRNA 32 increases expression EXP Bleomycin results in increased expression of MIR32 mRNA CTD PMID:25933445 NCBI chr 5:71,596,083...71,596,152
Ensembl chr 5:71,596,083...71,596,152
JBrowse link
G Mir320a microRNA 320a decreases expression EXP Bleomycin results in decreased expression of MIR320A mRNA CTD PMID:25933445 NCBI chr15:45,516,392...45,516,473
Ensembl chr15:45,516,392...45,516,473
JBrowse link
G Mir322 microRNA 322 decreases expression EXP Bleomycin results in decreased expression of MIR322 mRNA CTD PMID:25933445 NCBI chr  X:132,806,594...132,806,688 JBrowse link
G Mir324 microRNA 324 affects expression EXP Bleomycin affects the expression of MIR324 mRNA CTD PMID:25933445 NCBI chr10:54,734,680...54,734,762
Ensembl chr10:54,734,678...54,734,766
JBrowse link
G Mir326 microRNA 326 decreases expression EXP Bleomycin results in decreased expression of MIR326 mRNA CTD PMID:25933445 NCBI chr 1:153,854,029...153,854,123
Ensembl chr 1:153,854,029...153,854,123
JBrowse link
G Mir328 microRNA 328 affects expression EXP Bleomycin affects the expression of MIR328 mRNA CTD PMID:25933445 NCBI chr19:33,184,766...33,184,849
Ensembl chr19:33,184,766...33,184,849
JBrowse link
G Mir33 microRNA 33 decreases expression EXP Bleomycin results in decreased expression of MIR33 mRNA CTD PMID:25933445 NCBI chr 7:113,713,855...113,713,923
Ensembl chr 7:113,713,855...113,713,923
JBrowse link
G Mir330 microRNA 330 decreases expression EXP Bleomycin results in decreased expression of MIR330 mRNA CTD PMID:25933445 NCBI chr 1:78,833,178...78,833,274
Ensembl chr 1:78,833,178...78,833,274
JBrowse link
G Mir331 microRNA 331 decreases expression EXP Bleomycin results in decreased expression of MIR331 mRNA CTD PMID:25933445 NCBI chr 7:28,527,390...28,527,485
Ensembl chr 7:28,527,390...28,527,485
JBrowse link
G Mir340-1 microRNA mir-340-1 increases expression EXP Bleomycin results in increased expression of MIR340-1 mRNA CTD PMID:25933445 NCBI chr10:34,393,568...34,393,665 JBrowse link
G Mir342 microRNA 342 decreases expression EXP Bleomycin results in decreased expression of MIR342 mRNA CTD PMID:25933445 NCBI chr 6:127,565,269...127,565,367
Ensembl chr 6:127,565,269...127,565,367
JBrowse link
G Mir345 microRNA 345 decreases expression EXP Bleomycin results in decreased expression of MIR345 mRNA CTD PMID:25933445 NCBI chr 6:127,754,027...127,754,122
Ensembl chr 6:127,754,027...127,754,122
JBrowse link
G Mir347 microRNA mir-347 decreases expression EXP Bleomycin results in decreased expression of MIR347 mRNA CTD PMID:25933445
G Mir3473 microRNA 3473 increases expression EXP Bleomycin results in increased expression of MIR3473 mRNA CTD PMID:25933445 NCBI chr13:39,499,246...39,499,312
Ensembl chr13:39,499,246...39,499,312
JBrowse link
G Mir34a microRNA 34a affects expression EXP Bleomycin affects the expression of MIR34A mRNA CTD PMID:25933445 NCBI chr 5:160,533,002...160,533,103
Ensembl chr 5:160,533,002...160,533,103
JBrowse link
G Mir34b microRNA 34b decreases expression EXP Bleomycin results in decreased expression of MIR34B mRNA CTD PMID:25933445 NCBI chr 8:51,410,244...51,410,327
Ensembl chr 8:51,410,244...51,410,327
JBrowse link
G Mir34c microRNA 34c decreases expression EXP Bleomycin results in decreased expression of MIR34C mRNA CTD PMID:25933445 NCBI chr 8:51,409,726...51,409,802
Ensembl chr 8:51,409,726...51,409,802
JBrowse link
G Mir352 microRNA mir-352 decreases expression EXP Bleomycin results in decreased expression of MIR352 mRNA CTD PMID:25933445
G Mir3545 microRNA 3545 decreases expression EXP Bleomycin results in decreased expression of MIR203 mRNA CTD PMID:25933445 NCBI chr 6:131,199,542...131,199,656
Ensembl chr 6:131,199,542...131,199,656
JBrowse link
G Mir3573 microRNA 3573 decreases expression EXP Bleomycin results in decreased expression of MIR3573 mRNA CTD PMID:25933445 NCBI chr  X:64,259,096...64,259,167
Ensembl chr  X:64,259,096...64,259,167
JBrowse link
G Mir3584 microRNA 3584 affects expression EXP Bleomycin affects the expression of MIR3584 mRNA CTD PMID:25933445 NCBI chr 1:246,786,249...246,786,329 JBrowse link
G Mir361 microRNA 361 decreases expression EXP Bleomycin results in decreased expression of MIR361 mRNA CTD PMID:25933445 NCBI chr  X:78,246,206...78,246,275
Ensembl chr  X:78,246,206...78,246,275
JBrowse link
G Mir365b microRNA 365b decreases expression EXP Bleomycin results in decreased expression of MIR365B mRNA CTD PMID:25933445 NCBI chr10:64,686,255...64,686,340
Ensembl chr10:64,686,252...64,686,351
JBrowse link
G Mir374b microRNA 374b decreases expression EXP Bleomycin results in decreased expression of MIR374B mRNA CTD PMID:25933445 NCBI chr  X:68,591,732...68,591,799
Ensembl chr  X:68,591,732...68,591,799
JBrowse link
G Mir375 microRNA 375 decreases expression EXP Bleomycin results in decreased expression of MIR375 mRNA CTD PMID:25933445 NCBI chr 9:76,457,911...76,457,985
Ensembl chr 9:76,457,911...76,457,985
JBrowse link
G Mir378 microRNA 378 decreases expression EXP Bleomycin results in decreased expression of MIR378 mRNA CTD PMID:25933445 NCBI chr18:54,858,559...54,858,623 JBrowse link
G Mir409 microRNA 409 affects expression EXP Bleomycin affects the expression of MIR409 mRNA CTD PMID:25933445 NCBI chr 6:128,757,780...128,757,856 JBrowse link
G Mir423 microRNA 423 decreases expression EXP Bleomycin results in decreased expression of MIR423 mRNA CTD PMID:25933445 NCBI chr10:61,914,142...61,914,220
Ensembl chr10:61,914,133...61,914,226
JBrowse link
G Mir425 microRNA 425 affects expression EXP Bleomycin affects the expression of MIR425 mRNA CTD PMID:25933445 NCBI chr 8:109,264,555...109,264,637
Ensembl chr 8:109,264,555...109,264,637
JBrowse link
G Mir429 microRNA 429 decreases expression EXP Bleomycin results in decreased expression of MIR429 mRNA CTD PMID:25933445 NCBI chr 5:166,647,459...166,647,543
Ensembl chr 5:166,647,459...166,647,543
JBrowse link
G Mir449a microRNA 449a affects expression EXP Bleomycin affects the expression of MIR449A mRNA CTD PMID:25933445 NCBI chr 2:44,670,714...44,670,804
Ensembl chr 2:44,670,714...44,670,804
JBrowse link
G Mir450a1 microRNA 450a-1 decreases expression EXP Bleomycin results in decreased expression of MIR450A1 mRNA CTD PMID:25933445 NCBI chr  X:132,801,380...132,801,470 JBrowse link
G Mir451a microRNA 451a decreases expression EXP Bleomycin results in decreased expression of MIR451A mRNA CTD PMID:25933445 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591
JBrowse link
G Mir494 microRNA 494 decreases expression EXP Bleomycin results in decreased expression of MIR494 mRNA CTD PMID:25933445 NCBI chr 6:128,728,710...128,728,792
Ensembl chr 6:128,728,709...128,728,793
JBrowse link
G Mir497 microRNA 497 decreases expression EXP Bleomycin results in decreased expression of MIR497 mRNA CTD PMID:25933445 NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
JBrowse link
G Mir500 microRNA 500 affects expression EXP Bleomycin affects the expression of MIR500 mRNA CTD PMID:25933445 NCBI chr  X:15,258,778...15,258,857
Ensembl chr  X:15,258,768...15,258,859
JBrowse link
G Mir503 microRNA 503 decreases expression EXP Bleomycin results in decreased expression of MIR503 mRNA CTD PMID:25933445 NCBI chr  X:132,806,303...132,806,373 JBrowse link
G Mir532 microRNA 532 affects expression EXP Bleomycin affects the expression of MIR532 mRNA CTD PMID:25933445 NCBI chr  X:15,247,315...15,247,393
Ensembl chr  X:15,247,315...15,247,393
JBrowse link
G Mir542 microRNA 542 decreases expression EXP Bleomycin results in decreased expression of MIR542 mRNA CTD PMID:25933445 NCBI chr  X:132,802,623...132,802,701 JBrowse link
G Mir6215 microRNA 6215 decreases expression EXP Bleomycin results in decreased expression of MIR6215 mRNA CTD PMID:25933445 NCBI chr 5:151,850,759...151,850,825
Ensembl chr 5:151,850,759...151,850,825
JBrowse link
G Mir6216 microRNA 6216 decreases expression EXP Bleomycin results in decreased expression of MIR6216 mRNA CTD PMID:25933445 NCBI chr 3:44,756,861...44,756,938
Ensembl chr 3:44,756,861...44,756,938
JBrowse link
G Mir6328 microRNA 6328 affects expression EXP Bleomycin affects the expression of MIR6328 mRNA CTD PMID:25933445 NCBI chr20:2,885,300...2,885,396
Ensembl chr20:2,885,300...2,885,396
JBrowse link
G Mir652 microRNA 652 affects expression EXP Bleomycin affects the expression of MIR652 mRNA CTD PMID:25933445 NCBI chr  X:106,343,293...106,343,373
Ensembl chr  X:106,343,293...106,343,373
JBrowse link
G Mir93 microRNA 93 affects expression EXP Bleomycin affects the expression of MIR93 mRNA CTD PMID:25933445 NCBI chr12:17,043,135...17,043,221
Ensembl chr12:17,043,135...17,043,221
JBrowse link
G Mir96 microRNA 96 affects expression EXP Bleomycin affects the expression of MIR96 mRNA CTD PMID:25933445 NCBI chr 4:58,788,411...58,788,516
Ensembl chr 4:58,788,411...58,788,516
JBrowse link
G Mir98 microRNA 98 decreases expression EXP Bleomycin results in decreased expression of MIR98 mRNA CTD PMID:25933445 NCBI chr  X:20,981,235...20,981,342
Ensembl chr  X:20,981,235...20,981,342
JBrowse link
G Mir99a microRNA 99a decreases expression EXP Bleomycin results in decreased expression of MIR99A mRNA CTD PMID:25933445 NCBI chr11:16,200,443...16,200,523
Ensembl chr11:16,200,443...16,200,523
JBrowse link
G Mir99b microRNA 99b decreases expression EXP Bleomycin results in decreased expression of MIR99B mRNA CTD PMID:25933445 NCBI chr 1:58,677,015...58,677,084
Ensembl chr 1:58,677,011...58,677,090
JBrowse link
G Mirlet7b microRNA let-7b decreases expression EXP Bleomycin results in decreased expression of MIRLET7B mRNA CTD PMID:25933445 NCBI chr 7:116,804,186...116,804,270
Ensembl chr 7:116,804,186...116,804,270
JBrowse link
G Mirlet7d microRNA let-7d decreases expression EXP Bleomycin results in decreased expression of MIRLET7D mRNA CTD PMID:25933445 NCBI chr17:16,115,893...16,115,990
Ensembl chr17:16,115,893...16,115,990
JBrowse link
G Mirlet7i microRNA let-7i decreases expression EXP Bleomycin results in decreased expression of MIRLET7I mRNA CTD PMID:25933445 NCBI chr 7:58,642,485...58,642,569
Ensembl chr 7:58,642,480...58,642,571
JBrowse link
G Mmp1 matrix metallopeptidase 1 increases expression ISO Bleomycin results in increased expression of MMP1 mRNA; Bleomycin results in increased expression of MMP1 protein CTD PMID:18684396 NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097
JBrowse link
G Mmp2 matrix metallopeptidase 2 multiple interactions
increases expression
EXP
ISO
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP2 protein]
Bleomycin results in increased expression of MMP2 mRNA; Bleomycin results in increased expression of MMP2 protein
CTD PMID:23656969 PMID:26345256 PMID:26768587 PMID:29175452 NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
JBrowse link
G Mmp3 matrix metallopeptidase 3 multiple interactions
increases expression
ISO [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of CCN2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of MMP3 mRNA]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]] CTD PMID:28434932 NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961
JBrowse link
G Mmp7 matrix metallopeptidase 7 increases expression
multiple interactions
ISO Bleomycin results in increased expression of MMP7 protein
honokiol inhibits the reaction [Bleomycin results in increased expression of MMP7 protein]
CTD PMID:32032644 NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902
JBrowse link
G Mmp9 matrix metallopeptidase 9 increases expression
multiple interactions
EXP
ISO
Bleomycin results in increased expression of MMP9 protein
12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]
Bleomycin results in increased expression of MMP9 mRNA; Bleomycin results in increased expression of MMP9 protein
allyl sulfide inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of MMP9 protein]
CTD PMID:23656969 PMID:26526764 PMID:26768587 PMID:28300665 PMID:28694203 NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
JBrowse link
G Mpo myeloperoxidase multiple interactions
increases expression
increases activity
ISO
EXP
Oils, Volatile inhibits the reaction [Bleomycin results in increased activity of MPO protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased activity of MPO protein]; verlukast inhibits the reaction [Bleomycin results in increased activity of MPO protein]; zileuton inhibits the reaction [Bleomycin results in increased activity of MPO protein]
Bleomycin results in increased expression of MPO protein
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MPO protein]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MPO protein]; resveratrol inhibits the reaction [Bleomycin results in increased activity of MPO protein]
CTD PMID:16317386 PMID:17035056 PMID:17118201 PMID:26093215 PMID:28850077 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrc1 mannose receptor, C type 1 increases expression ISO Bleomycin results in increased expression of MRC1 mRNA CTD PMID:29033951 NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857
JBrowse link
G Msn moesin decreases expression EXP Bleomycin results in decreased expression of MSN protein CTD PMID:25933445 NCBI chr  X:60,996,043...61,064,011
Ensembl chr  X:60,995,951...61,065,628
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of MUC5AC mRNA
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of MUC5AC mRNA]
CTD PMID:18684396 PMID:26093215 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Mug1 murinoglobulin 1 increases expression EXP Bleomycin results in increased expression of PZP protein CTD PMID:25933445 NCBI chr 4:155,076,270...155,130,051
Ensembl chr 4:155,076,312...155,130,051
JBrowse link
G Mxi1 MAX interactor 1, dimerization protein decreases expression ISO Bleomycin results in decreased expression of MXI1 mRNA CTD PMID:33770205 NCBI chr 1:252,323,915...252,383,682
Ensembl chr 1:252,323,303...252,383,681
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases response to substance ISO MYC protein results in increased susceptibility to Bleomycin CTD PMID:10449034 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Myh11 myosin heavy chain 11 decreases expression EXP Bleomycin results in decreased expression of MYH11 protein CTD PMID:25933445 NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
JBrowse link
G Myh6 myosin heavy chain 6 decreases expression EXP Bleomycin results in decreased expression of MYH6 protein CTD PMID:25933445 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720
JBrowse link
G Myl12b myosin light chain 12B increases expression EXP Bleomycin results in increased expression of MYL12B protein CTD PMID:25933445 NCBI chr 9:110,873,855...110,888,187 JBrowse link
G Myl4 myosin, light chain 4 decreases expression EXP Bleomycin results in decreased expression of MYL4 protein CTD PMID:25933445 NCBI chr10:89,449,456...89,485,365
Ensembl chr10:89,449,443...89,485,363
JBrowse link
G Myl6 myosin light chain 6 increases expression EXP Bleomycin results in increased expression of MYL6 protein CTD PMID:25933445 NCBI chr 7:910,764...914,062
Ensembl chr 7:910,774...933,791
JBrowse link
G Myo1c myosin 1C decreases expression EXP Bleomycin results in decreased expression of MYO1C protein CTD PMID:25933445 NCBI chr10:60,498,374...60,520,752
Ensembl chr10:60,498,280...60,520,752
JBrowse link
G Myo1e myosin IE decreases expression ISO Bleomycin results in decreased expression of MYO1E mRNA CTD PMID:33770205 NCBI chr 8:70,887,934...71,080,180
Ensembl chr 8:70,887,870...71,080,169
JBrowse link
G Nap1l1 nucleosome assembly protein 1-like 1 decreases expression ISO Bleomycin results in decreased expression of NAP1L1 protein CTD PMID:29733421 NCBI chr 7:46,933,278...46,957,853
Ensembl chr 7:46,933,356...46,956,593
JBrowse link
G Nfatc2 nuclear factor of activated T-cells 2 multiple interactions
increases expression
ISO MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of NFATC2 mRNA] CTD PMID:28726637 NCBI chr 3:157,195,970...157,328,640
Ensembl chr 3:157,198,872...157,328,325
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions
decreases expression
increases expression
increases phosphorylation
ISO
EXP
Bleomycin affects the localization of NFE2L2 protein
Berberine promotes the reaction [Bleomycin results in increased expression of NFE2L2 protein]; celastrol inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 mRNA]
Bleomycin results in decreased expression of NFE2L2 mRNA; Bleomycin results in decreased expression of NFE2L2 protein
caffeic acid phenethyl ester inhibits the reaction [Bleomycin results in decreased expression of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin affects the localization of NFE2L2 protein]; U 0126 inhibits the reaction [Bleomycin results in increased phosphorylation of NFE2L2 protein]
CTD PMID:23523906 PMID:23570914 PMID:26093215 PMID:26768587 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 increases activity
multiple interactions
increases expression
ISO
EXP
Bleomycin results in increased activity of NFKB1 protein
NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]
Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of NFKB1 mRNA]
CTD PMID:12003776 PMID:26093215 PMID:26526764 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO [Bleomycin results in increased phosphorylation of GSK3B protein] inhibits the reaction [GSK3B protein binds to and results in increased stability of NFKBIA protein] CTD PMID:19429264 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nit2 nitrilase family, member 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of NIT2 protein CTD PMID:29733421 NCBI chr11:43,363,839...43,378,713
Ensembl chr11:43,363,985...43,375,024
JBrowse link
G Nmbr neuromedin B receptor decreases expression EXP Bleomycin results in decreased expression of NMBR mRNA CTD PMID:15808516 NCBI chr 1:9,115,033...9,146,081
Ensembl chr 1:9,134,889...9,145,462
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 increases expression EXP Bleomycin results in increased expression of NME2 protein CTD PMID:25933445 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nos2 nitric oxide synthase 2 increases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of NOS2 protein
Berberine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
Bleomycin results in increased expression of NOS2 mRNA; Bleomycin results in increased expression of NOS2 protein
15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]; NOS2 protein affects the reaction [Bleomycin results in increased activity of NFKB1 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of LGALS3 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of MMP9 protein]; NOS2 protein affects the reaction [Bleomycin results in increased expression of RETNLA protein]; rosiglitazone inhibits the reaction [Bleomycin results in increased expression of NOS2 protein]
CTD PMID:15684285 PMID:17434272 PMID:19362168 PMID:23523906 PMID:26526764 More... NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Npm1 nucleophosmin 1 increases expression EXP Bleomycin results in increased expression of NPM1 protein CTD PMID:25933445 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 decreases activity
multiple interactions
EXP Bleomycin results in decreased activity of NQO1 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of NQO1 protein]
CTD PMID:26768587 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression EXP Bleomycin results in decreased expression of NR3C1 mRNA CTD PMID:15808516 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375
JBrowse link
G Nr3c2 nuclear receptor subfamily 3, group C, member 2 decreases expression EXP Bleomycin results in decreased expression of NR3C2 mRNA CTD PMID:15808516 NCBI chr19:30,715,648...31,059,885
Ensembl chr19:30,715,648...31,059,885
JBrowse link
G Nucb2 nucleobindin 2 increases expression EXP Bleomycin results in increased expression of NUCB2 protein CTD PMID:25933445 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353
JBrowse link
G Oat ornithine aminotransferase multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of OAT protein CTD PMID:29733421 NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
JBrowse link
G Ostf1 osteoclast stimulating factor 1 increases expression EXP Bleomycin results in increased expression of OSTF1 protein CTD PMID:25933445 NCBI chr 1:216,002,037...216,049,250
Ensembl chr 1:216,002,044...216,049,221
JBrowse link
G P4hb prolyl 4-hydroxylase subunit beta increases expression EXP Bleomycin results in increased expression of P4HB protein CTD PMID:25933445 NCBI chr10:105,836,972...105,848,583
Ensembl chr10:105,836,982...105,848,500
JBrowse link
G Pabpc1 poly(A) binding protein, cytoplasmic 1 increases expression EXP Bleomycin results in increased expression of PABPC1 protein CTD PMID:25933445 NCBI chr 7:67,777,438...67,789,731
Ensembl chr 7:67,777,381...67,789,744
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 increases expression
multiple interactions
increases cleavage
ISO
EXP
Bleomycin results in increased expression of PARP1 protein
Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein]
Bleomycin results in increased cleavage of PARP1 protein
CTD PMID:15371238 PMID:16317386 PMID:32278510 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Pcbp2 poly(rC) binding protein 2 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PCBP2 protein CTD PMID:29733421 NCBI chr 7:133,605,480...133,631,312
Ensembl chr 7:133,605,573...133,629,863
JBrowse link
G Pdia3 protein disulfide isomerase family A, member 3 multiple interactions EXP [Bleomycin co-treated with Cisplatin co-treated with Etoposide] results in increased expression of PDIA3 protein CTD PMID:24478030 NCBI chr 3:108,388,189...108,412,013
Ensembl chr 3:108,388,245...108,413,236
JBrowse link
G Pdlim1 PDZ and LIM domain 1 increases expression EXP Bleomycin results in increased expression of PDLIM1 protein CTD PMID:25933445 NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
JBrowse link
G Pdlim5 PDZ and LIM domain 5 increases expression EXP Bleomycin results in increased expression of PDLIM5 protein CTD PMID:25933445 NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275
JBrowse link
G Plau plasminogen activator, urokinase increases expression
decreases expression
ISO Bleomycin results in increased expression of PLAU mRNA; Bleomycin results in increased expression of PLAU protein
Bleomycin results in decreased expression of PLAU protein
CTD PMID:25648892 NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
JBrowse link
G Pml PML nuclear body scaffold multiple interactions
increases expression
ISO arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
JBrowse link
G Pnp purine nucleoside phosphorylase decreases expression EXP Bleomycin results in decreased expression of PNP protein CTD PMID:25933445 NCBI chr15:24,170,456...24,178,274
Ensembl chr15:24,170,602...24,203,986
JBrowse link
G Podxl podocalyxin-like decreases expression EXP Bleomycin results in decreased expression of PODXL protein CTD PMID:25933445 NCBI chr 4:60,135,124...60,181,829
Ensembl chr 4:60,135,109...60,181,899
JBrowse link
G Polb DNA polymerase beta decreases response to substance ISO POLB results in decreased susceptibility to Bleomycin CTD PMID:21251944 NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha multiple interactions
decreases response to substance
ISO PPARA protein affects the reaction [Bleomycin results in increased expression of HMOX1 protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of IL1B protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]
PPARA protein results in decreased susceptibility to Bleomycin
CTD PMID:16317386 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression
multiple interactions
ISO Bleomycin results in decreased expression of PPARG mRNA; Bleomycin results in decreased expression of PPARG protein
Berberine inhibits the reaction [Bleomycin binds to PPARG protein]
lenabasum inhibits the reaction [Bleomycin results in decreased expression of PPARG protein]; Rosiglitazone inhibits the reaction [Bleomycin results in decreased expression of PPARG mRNA]
CTD PMID:19147827 PMID:27153807 PMID:29408570 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Ppia peptidylprolyl isomerase A increases expression EXP Bleomycin results in increased expression of PPIA protein CTD PMID:25933445 NCBI chr14:81,279,292...81,282,960
Ensembl chr14:81,275,091...81,299,601
JBrowse link
G Prdx2 peroxiredoxin 2 decreases expression EXP Bleomycin results in decreased expression of PRDX2 protein CTD PMID:25933445 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194
JBrowse link
G Prdx6 peroxiredoxin 6 decreases expression EXP Bleomycin results in decreased expression of PRDX6 protein CTD PMID:25933445 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Prelp proline and arginine rich end leucine rich repeat protein decreases expression EXP Bleomycin results in decreased expression of PRELP protein CTD PMID:25933445 NCBI chr13:45,368,407...45,391,480
Ensembl chr13:45,370,533...45,380,270
JBrowse link
G Psmd13 proteasome 26S subunit, non-ATPase 13 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of PSMD13 protein CTD PMID:29733421 NCBI chr 1:195,964,617...195,976,895
Ensembl chr 1:195,964,138...195,976,905
JBrowse link
G Psme1 proteasome activator subunit 1 increases expression EXP Bleomycin results in increased expression of PSME1 protein CTD PMID:25933445 NCBI chr15:29,069,012...29,071,888
Ensembl chr15:29,068,729...29,071,890
JBrowse link
G Psme2 proteasome activator subunit 2 decreases expression EXP Bleomycin results in decreased expression of PSME2 protein CTD PMID:25933445 NCBI chr15:29,078,495...29,082,794
Ensembl chr15:29,078,500...29,082,946
JBrowse link
G Ptbp1 polypyrimidine tract binding protein 1 increases expression EXP Bleomycin results in increased expression of PTBP1 protein CTD PMID:25933445 NCBI chr 7:9,842,574...9,852,332
Ensembl chr 7:9,842,574...9,852,397
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions
decreases expression
ISO ((3Z)-N-(3-chlorophenyl)-3-((3,5-dimethyl-4-((4-methylpiperazin-1-yl)carbonyl)-1H-pyrrol-2-yl)methylene)-N-methyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide) inhibits the reaction [Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN mRNA]; Berberine inhibits the reaction [Bleomycin results in decreased expression of PTEN protein]
Bleomycin results in decreased expression of PTEN mRNA; Bleomycin results in decreased expression of PTEN protein
CTD PMID:29408570 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgdr prostaglandin D2 receptor increases expression ISO Bleomycin results in increased expression of PTGDR mRNA CTD PMID:20719937 NCBI chr15:17,360,304...17,367,679 JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression
multiple interactions
ISO Bleomycin results in increased expression of PTGS2 mRNA; Bleomycin results in increased expression of PTGS2 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of PTGS2 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased expression of PTGS2 mRNA]
CTD PMID:26526764 PMID:27704718 PMID:32828905 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Ptms parathymosin increases expression EXP Bleomycin results in increased expression of PTMS protein CTD PMID:25933445 NCBI chr 4:157,722,384...157,726,575
Ensembl chr 4:157,722,386...157,727,009
JBrowse link
G Rab1b RAB1B, member RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAB1B protein CTD PMID:25933445 NCBI chr 1:202,405,759...202,413,850
Ensembl chr 1:202,405,759...202,413,868
JBrowse link
G Ralb RAS like proto-oncogene B increases expression EXP Bleomycin results in increased expression of RALB protein CTD PMID:25933445 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Rap1b RAP1B, member of RAS oncogene family increases expression EXP Bleomycin results in increased expression of RAP1B protein CTD PMID:25933445 NCBI chr 7:53,423,039...53,456,388
Ensembl chr 7:53,423,130...53,456,370
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions
decreases expression
increases expression
ISO
EXP
Calcitriol inhibits the reaction [Bleomycin results in increased expression of RELA protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of RELA protein modified form]; methyl palmitate inhibits the reaction [Bleomycin results in increased expression of RELA protein]
Bleomycin results in decreased expression of RELA mRNA
Bleomycin results in increased expression of RELA protein; Bleomycin results in increased expression of RELA protein modified form
Berberine inhibits the reaction [Bleomycin affects the localization of and results in increased expression of RELA protein]; Bleomycin affects the localization of and results in increased expression of RELA protein; thymoquinone inhibits the reaction [Bleomycin results in increased expression of RELA protein]
CTD PMID:21575650 PMID:22982510 PMID:23523906 PMID:26520185 PMID:29720568 More... NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit decreases expression ISO Bleomycin results in decreased expression of RELB mRNA CTD PMID:29720568 NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507
JBrowse link
G RGD1562690 similar to L-lactate dehydrogenase A chain (LDH-A) (LDH muscle subunit) (LDH-M) decreases expression EXP Bleomycin results in decreased expression of RGD1562690 protein CTD PMID:25933445 NCBI chr 8:30,363,220...30,364,836 JBrowse link
G RGD1566085 similar to pyridoxal (pyridoxine, vitamin B6) kinase increases expression EXP Bleomycin results in increased expression of PDXK protein CTD PMID:25933445 NCBI chr20:10,162,934...10,192,610 JBrowse link
G Rpl12 ribosomal protein L12 increases expression EXP Bleomycin results in increased expression of RPL12 protein CTD PMID:25933445 NCBI chr 3:16,264,269...16,266,645
Ensembl chr 3:16,264,251...16,266,642
JBrowse link
G Rpl13 ribosomal protein L13 increases expression EXP Bleomycin results in increased expression of RPL13 protein CTD PMID:25933445 NCBI chr19:51,153,990...51,156,541
Ensembl chr19:51,153,924...51,163,014
JBrowse link
G Rpl4 ribosomal protein L4 increases expression EXP Bleomycin results in increased expression of RPL4 protein CTD PMID:25933445 NCBI chr 8:64,671,177...64,676,301
Ensembl chr 8:64,671,160...64,676,306
JBrowse link
G Rpl5 ribosomal protein L5 increases expression EXP Bleomycin results in increased expression of RPL5 protein CTD PMID:25933445 NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
JBrowse link
G Rpl6 ribosomal protein L6 affects expression EXP Bleomycin affects the expression of RPL6 protein CTD PMID:25933445 NCBI chr12:35,347,493...35,352,011
Ensembl chr12:35,347,497...35,351,921
JBrowse link
G Rps3a ribosomal protein S3a increases expression EXP Bleomycin results in increased expression of RPS3A1 protein CTD PMID:25933445 NCBI chr 2:171,524,685...171,529,054
Ensembl chr 2:171,524,500...171,529,055
JBrowse link
G S100a11 S100 calcium binding protein A11 increases expression EXP Bleomycin results in increased expression of S100A11 protein CTD PMID:25933445 NCBI chr 2:179,191,504...179,197,098
Ensembl chr 2:179,191,715...179,197,044
JBrowse link
G S100a4 S100 calcium-binding protein A4 increases expression
multiple interactions
EXP Bleomycin results in increased expression of S100A4 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of S100A4 protein]
CTD PMID:25933445 PMID:31706003 NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254
JBrowse link
G S100a6 S100 calcium binding protein A6 affects expression EXP Bleomycin affects the expression of S100A6 protein CTD PMID:25933445 NCBI chr 2:176,100,619...176,102,181
Ensembl chr 2:176,100,899...176,102,180
JBrowse link
G S100a8 S100 calcium binding protein A8 increases expression EXP Bleomycin results in increased expression of S100A8 protein CTD PMID:25933445 NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 multiple interactions ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein CTD PMID:29033951 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681
JBrowse link
G S1pr3 sphingosine-1-phosphate receptor 3 multiple interactions
increases expression
ISO S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA] CTD PMID:29033951 NCBI chr17:13,781,050...13,794,408
Ensembl chr17:13,781,050...13,794,505
JBrowse link
G S1pr5 sphingosine-1-phosphate receptor 5 multiple interactions
affects response to substance
ISO [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of COMP protein; [S1PR5 protein affects the susceptibility to Bleomycin] which affects the expression of S1PR1 protein; S1PR5 protein affects the reaction [Bleomycin results in increased expression of COL1A1 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of GATA3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of S1PR3 mRNA]; S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA] CTD PMID:29033951 NCBI chr 8:19,786,676...19,791,862
Ensembl chr 8:19,786,663...19,791,795
JBrowse link
G Scarna15 small Cajal body-specific RNA 15 affects expression EXP Bleomycin affects the expression of SCARNA15 mRNA CTD PMID:25933445 NCBI chr 1:135,484,620...135,484,683 JBrowse link
G Scgb1a1 secretoglobin family 1A member 1 decreases expression EXP Bleomycin results in decreased expression of SCGB1A1 protein CTD PMID:25933445 NCBI chr 1:205,977,060...205,980,610
Ensembl chr 1:205,977,060...205,980,610
JBrowse link
G Scp2 sterol carrier protein 2 increases expression EXP Bleomycin results in increased expression of SCP2 protein CTD PMID:25933445 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
G Scpep1 serine carboxypeptidase 1 increases expression EXP Bleomycin results in increased expression of SCPEP1 protein CTD PMID:25933445 NCBI chr10:73,703,275...73,732,892
Ensembl chr10:73,703,278...73,732,850
JBrowse link
G Sec14l3 SEC14-like lipid binding 3 decreases expression EXP Bleomycin results in decreased expression of SEC14L3 protein CTD PMID:25933445 NCBI chr14:78,944,568...78,955,608 JBrowse link
G Selenbp1 selenium binding protein 1 decreases expression EXP Bleomycin results in decreased expression of SELENBP1 protein CTD PMID:25933445
G Serpine1 serpin family E member 1 increases expression ISO Bleomycin results in increased expression of SERPINE1 protein CTD PMID:29175452 NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
JBrowse link
G Serpinh1 serpin family H member 1 multiple interactions
increases expression
EXP allyl sulfide inhibits the reaction [Bleomycin results in increased expression of SERPINH1 protein] CTD PMID:23656969 PMID:25933445 NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801
JBrowse link
G Sfrp1 secreted frizzled-related protein 1 increases expression ISO Bleomycin results in increased expression of SFRP1 mRNA CTD PMID:26345256 NCBI chr16:68,575,763...68,613,905
Ensembl chr16:68,575,763...68,614,286
JBrowse link
G Sftpa1 surfactant protein A1 multiple interactions
increases expression
decreases expression
ISO
EXP
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of CXCL8 protein; [Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]
Bleomycin results in increased expression of SFTPA1 protein
Bleomycin results in decreased expression of SFTPA1 mRNA
CTD PMID:14617519 PMID:15782499 PMID:25933445 NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685
JBrowse link
G Sftpb surfactant protein B decreases expression
multiple interactions
EXP
ISO
Bleomycin results in decreased expression of SFTPB mRNA
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein
CTD PMID:15782499 PMID:33647319 NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436
JBrowse link
G Sftpd surfactant protein D increases expression
multiple interactions
increases metabolic processing
EXP
ISO
Bleomycin results in increased expression of SFTPD mRNA; Bleomycin results in increased expression of SFTPD protein
[TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Bleomycin promotes the reaction [SFTPD protein binds to SFTPD protein binds to SFTPD protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide inhibits the reaction [Bleomycin results in increased metabolism of SFTPD protein]
CTD PMID:11880309 PMID:25933445 PMID:26526764 PMID:33647319 NCBI chr16:17,046,491...17,058,968
Ensembl chr16:17,046,483...17,059,927
JBrowse link
G Sirt1 sirtuin 1 decreases expression
multiple interactions
ISO Bleomycin results in decreased expression of SIRT1 mRNA; Bleomycin results in decreased expression of SIRT1 protein
resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 mRNA]; resveratrol inhibits the reaction [Bleomycin results in decreased expression of SIRT1 protein]
CTD PMID:25707573 NCBI chr20:25,307,143...25,329,260
Ensembl chr20:25,306,917...25,329,260
JBrowse link
G Slc12a1 solute carrier family 12 member 1 increases expression EXP Bleomycin results in increased expression of SLC12A1 mRNA CTD PMID:15808516 NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899
JBrowse link
G Slc1a2 solute carrier family 1 member 2 increases expression EXP Bleomycin results in increased expression of SLC1A2 mRNA CTD PMID:15808516 NCBI chr 3:89,005,129...89,126,498
Ensembl chr 3:89,005,129...89,126,498
JBrowse link
G Slc25a4 solute carrier family 25 member 4 decreases expression EXP Bleomycin results in decreased expression of SLC25A4 protein CTD PMID:25933445 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733
JBrowse link
G Slc25a5 solute carrier family 25 member 5 decreases expression EXP Bleomycin results in decreased expression of SLC25A5 protein CTD PMID:25933445 NCBI chr  X:116,031,896...116,034,963
Ensembl chr  X:116,031,803...116,034,967
JBrowse link
G Slc6a12 solute carrier family 6 member 12 increases expression EXP Bleomycin results in increased expression of SLC6A12 mRNA CTD PMID:15808516 NCBI chr 4:154,585,386...154,603,750
Ensembl chr 4:154,585,500...154,603,750
JBrowse link
G Slc9a3r1 SLC9A3 regulator 1 increases expression EXP Bleomycin results in increased expression of SLC9A3R1 protein CTD PMID:25933445 NCBI chr10:100,403,189...100,420,290
Ensembl chr10:100,403,069...100,420,598
JBrowse link
G Slc9a3r2 SLC9A3 regulator 2 decreases expression EXP Bleomycin results in decreased expression of SLC9A3R2 protein CTD PMID:25933445 NCBI chr10:13,662,461...13,672,975
Ensembl chr10:13,662,461...13,673,049
JBrowse link
G Slco2a1 solute carrier organic anion transporter family, member 2a1 increases response to substance
multiple interactions
ISO SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin
[SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of CCL5 mRNA]; SLCO2A1 gene mutant form promotes the reaction [Bleomycin results in increased expression of IL1B mRNA]
CTD PMID:32828905 NCBI chr 8:103,588,916...103,672,546
Ensembl chr 8:103,588,916...103,672,546
JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 multiple interactions ISO Bleomycin inhibits the reaction [SLCO2B1 protein results in increased uptake of Cascade Blue] CTD PMID:30863990 NCBI chr 1:153,959,288...154,007,294
Ensembl chr 1:153,959,293...154,007,353
JBrowse link
G Slpi secretory leukocyte peptidase inhibitor increases expression ISO Bleomycin results in increased expression of SLPI protein CTD PMID:26345256 NCBI chr 3:153,082,208...153,084,457
Ensembl chr 3:153,082,369...153,084,453
JBrowse link
G Smad2 SMAD family member 2 increases phosphorylation
multiple interactions
ISO Bleomycin results in increased phosphorylation of SMAD2 protein
camostat inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD2 protein]
CTD PMID:26599507 PMID:32032644 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Smad3 SMAD family member 3 multiple interactions
increases phosphorylation
increases expression
EXP
ISO
Phytochemicals inhibits the reaction [Bleomycin results in increased expression of SMAD3 mRNA]
Bleomycin results in increased phosphorylation of SMAD3 protein
2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]; honokiol inhibits the reaction [Bleomycin results in increased phosphorylation of SMAD3 protein]
CTD PMID:26093215 PMID:27704718 PMID:32032644 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
JBrowse link
G Smad7 SMAD family member 7 decreases expression
multiple interactions
increases expression
EXP
ISO
Bleomycin results in decreased expression of SMAD7 mRNA
S1PR5 protein affects the reaction [Bleomycin results in increased expression of SMAD7 mRNA]
CTD PMID:26093215 PMID:29033951 NCBI chr18:68,988,429...69,016,774
Ensembl chr18:68,988,429...69,016,765
JBrowse link
G Smc1a structural maintenance of chromosomes 1A increases phosphorylation ISO Bleomycin results in increased phosphorylation of SMC1A protein CTD PMID:24933654 NCBI chr  X:21,103,323...21,148,053
Ensembl chr  X:21,103,282...21,148,056
JBrowse link
G Smim14 small integral membrane protein 14 decreases expression ISO Bleomycin results in decreased expression of SMIM14 mRNA CTD PMID:33770205 NCBI chr14:42,783,361...42,829,762
Ensembl chr14:42,783,332...42,829,760
JBrowse link
G Snora58 small nucleolar RNA, H/ACA box 58 decreases expression EXP Bleomycin results in decreased expression of SNORA58 mRNA CTD PMID:25933445 NCBI chr 6:107,080,945...107,081,020
Ensembl chr 6:107,080,945...107,081,020
JBrowse link
G Socs1 suppressor of cytokine signaling 1 decreases expression ISO Bleomycin results in decreased expression of SOCS1 mRNA CTD PMID:17374387 NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
JBrowse link
G Sod1 superoxide dismutase 1 increases expression
decreases expression
multiple interactions
ISO
EXP
Bleomycin results in increased expression of SOD1 protein
Bleomycin results in decreased expression of SOD1 protein
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]
CTD PMID:8317554 PMID:25933445 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 increases expression
multiple interactions
decreases activity
ISO
EXP
Bleomycin results in increased expression of SOD2 protein
celastrol inhibits the reaction [Bleomycin results in decreased activity of SOD2 protein]
IL1A protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; IL1B protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
CTD PMID:8317554 PMID:26768587 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sparc secreted protein acidic and cysteine rich increases response to substance ISO SPARC protein results in increased susceptibility to Bleomycin CTD PMID:19446018 NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
JBrowse link
G Sparcl1 SPARC like 1 decreases expression EXP Bleomycin results in decreased expression of SPARCL1 protein CTD PMID:25933445 NCBI chr14:5,632,816...5,663,866
Ensembl chr14:5,632,569...5,663,865
JBrowse link
G Spp1 secreted phosphoprotein 1 increases expression ISO Bleomycin results in increased expression of SPP1 mRNA; Bleomycin results in increased expression of SPP1 protein CTD PMID:26345256 PMID:29175452 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Sptan1 spectrin, alpha, non-erythrocytic 1 decreases expression EXP Bleomycin results in decreased expression of SPTAN1 protein CTD PMID:25933445 NCBI chr 3:13,241,164...13,306,047
Ensembl chr 3:13,241,217...13,306,046
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO Bleomycin results in increased expression of SRXN1 mRNA CTD PMID:22003191 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Sstr1 somatostatin receptor 1 decreases expression EXP Bleomycin results in decreased expression of SSTR1 mRNA CTD PMID:15808516 NCBI chr 6:75,832,292...75,836,806
Ensembl chr 6:75,832,530...75,836,802
JBrowse link
G Sstr2 somatostatin receptor 2 decreases expression EXP Bleomycin results in decreased expression of SSTR2 mRNA CTD PMID:15808516 NCBI chr10:98,664,204...98,671,370
Ensembl chr10:98,664,216...98,674,351
JBrowse link
G Sstr3 somatostatin receptor 3 decreases expression EXP Bleomycin results in decreased expression of SSTR3 mRNA CTD PMID:15808516 NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
JBrowse link
G St14 ST14 transmembrane serine protease matriptase multiple interactions ISO Bleomycin results in increased expression of and results in increased activity of ST14 protein CTD PMID:26599507 NCBI chr 8:29,540,805...29,581,704
Ensembl chr 8:29,540,811...29,581,517
JBrowse link
G St3gal5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 decreases expression ISO Bleomycin results in decreased expression of ST3GAL5 mRNA CTD PMID:33770205 NCBI chr 4:104,134,553...104,192,560
Ensembl chr 4:104,134,613...104,192,558
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions
increases expression
ISO honokiol inhibits the reaction [Bleomycin results in increased expression of STAT3 protein modified form] CTD PMID:32032644 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Stat6 signal transducer and activator of transcription 6 multiple interactions
decreases response to substance
ISO STAT6 protein affects the reaction [Bleomycin results in increased expression of RETNLA mRNA]
STAT6 gene mutant form results in decreased susceptibility to Bleomycin
CTD PMID:15322207 NCBI chr 7:63,480,229...63,497,551
Ensembl chr 7:63,479,642...63,498,495
JBrowse link
G Stk11 serine/threonine kinase 11 increases expression
multiple interactions
ISO Bleomycin results in increased expression of STK11 protein
Soot inhibits the reaction [Bleomycin results in increased expression of STK11 protein]
CTD PMID:31302203 NCBI chr 7:9,574,553...9,591,315
Ensembl chr 7:9,575,269...9,591,315
JBrowse link
G Stmn1 stathmin 1 increases expression EXP Bleomycin results in increased expression of STMN1 protein CTD PMID:25933445 NCBI chr 5:146,680,757...146,687,154
Ensembl chr 5:146,681,436...146,687,154
JBrowse link
G Sv2b synaptic vesicle glycoprotein 2b increases expression EXP Bleomycin results in increased expression of SV2B mRNA CTD PMID:15808516 NCBI chr 1:128,978,471...129,152,479
Ensembl chr 1:128,978,473...129,152,479
JBrowse link
G Tacr2 tachykinin receptor 2 decreases expression EXP Bleomycin results in decreased expression of TACR2 mRNA CTD PMID:15808516 NCBI chr20:30,208,907...30,223,446
Ensembl chr20:30,208,907...30,223,446
JBrowse link
G Tagln transgelin increases expression EXP Bleomycin results in increased expression of TAGLN protein CTD PMID:25933445 NCBI chr 8:46,224,939...46,230,413
Ensembl chr 8:46,222,472...46,230,668
JBrowse link
G Tagln2 transgelin 2 increases expression EXP Bleomycin results in increased expression of TAGLN2 protein CTD PMID:25933445 NCBI chr13:84,966,980...84,973,973
Ensembl chr13:84,967,009...84,973,972
JBrowse link
G Taldo1 transaldolase 1 decreases expression EXP Bleomycin results in decreased expression of TALDO1 protein CTD PMID:25933445 NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974
JBrowse link
G Tbx21 T-box transcription factor 21 increases expression ISO Bleomycin results in increased expression of TBX21 mRNA CTD PMID:29033951 NCBI chr10:82,082,322...82,098,831
Ensembl chr10:82,082,322...82,098,831
JBrowse link
G Tcp1 t-complex 1 multiple interactions ISO [Etoposide co-treated with Cisplatin co-treated with Bleomycin] results in decreased expression of TCP1 protein CTD PMID:29733421 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tent4b terminal nucleotidyltransferase 4B decreases expression ISO Bleomycin results in decreased expression of TENT4B mRNA CTD PMID:33770205 NCBI chr19:18,807,616...18,868,969
Ensembl chr19:18,807,525...18,869,537
JBrowse link
G Tert telomerase reverse transcriptase decreases response to substance ISO TERT gene mutant form results in decreased susceptibility to Bleomycin CTD PMID:18008008 NCBI chr 1:29,637,213...29,659,509
Ensembl chr 1:29,637,506...29,659,561
JBrowse link
G Tf transferrin increases expression EXP Bleomycin results in increased expression of TF protein CTD PMID:25933445 NCBI chr 8:103,789,780...103,816,487
Ensembl chr 8:103,767,995...103,816,511
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions
increases expression
increases secretion
ISO
EXP
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; 12-(3-adamantan-1-ylureido)dodecanoic acid inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; camostat inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCL11 protein promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; lenabasum inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; N-((3-(aminomethyl)phenyl)methyl)ethanimidamide promotes the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Rosiglitazone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; SPL-334 inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
Bleomycin results in increased expression of TGFB1 mRNA; Bleomycin results in increased expression of TGFB1 protein
Bleomycin results in increased secretion of TGFB1 protein
andrographolide inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; angiotensin I (1-7) inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Berberine inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Curcumin inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Hydrocortisone inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]; Valsartan inhibits the reaction [Bleomycin results in increased expression of TGFB1 protein]
CTD PMID:14609568 PMID:15541506 PMID:16115399 PMID:16314464 PMID:17035056 More... NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 decreases expression EXP Bleomycin results in decreased expression of TGFB1I1 protein CTD PMID:25933445 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Tgfb2 transforming growth factor, beta 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFB2 mRNA] CTD PMID:28434932 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
JBrowse link
G Tgfb3 transforming growth factor, beta 3 increases expression
multiple interactions
ISO Bleomycin results in increased expression of TGFB3 mRNA
CCL12 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]; HIF1A protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]; MMP3 protein affects the reaction [Dinoprostone inhibits the reaction [Bleomycin results in increased expression of TGFB3 mRNA]]
CTD PMID:28434932 NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions
increases expression
ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
MIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]
CTD PMID:28434932 PMID:28726637 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 multiple interactions ISO [CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR2 mRNA] CTD PMID:28434932 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
JBrowse link
G Thbs1 thrombospondin 1 increases expression ISO Bleomycin results in increased expression of THBS1 mRNA CTD PMID:29720568 NCBI chr 3:105,056,286...105,071,445
Ensembl chr 3:105,056,292...105,071,440
JBrowse link
G Thop1 thimet oligopeptidase 1 decreases expression ISO Bleomycin results in decreased expression of THOP1 protein CTD PMID:29733421 NCBI chr 7:8,632,911...8,645,339
Ensembl chr 7:8,632,916...8,645,275
JBrowse link
G Thrb thyroid hormone receptor beta decreases expression EXP Bleomycin results in decreased expression of THRB mRNA CTD PMID:15808516 NCBI chr15:7,685,180...8,031,920
Ensembl chr15:7,685,180...7,882,916
JBrowse link
G Timp1 TIMP metallopeptidase inhibitor 1 increases expression
multiple interactions
ISO Bleomycin results in increased expression of TIMP1 mRNA; Bleomycin results in increased expression of TIMP1 protein
Dexamethasone inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; Grape Seed Extract inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]; honokiol inhibits the reaction [Bleomycin results in increased expression of TIMP1 protein]
CTD PMID:26345256 PMID:28300665 PMID:32032644 NCBI chr  X:1,212,969...1,217,714
Ensembl chr  X:1,212,972...1,217,664
JBrowse link
G Tlr1 toll-like receptor 1 decreases expression ISO Bleomycin results in decreased expression of TLR1 mRNA CTD PMID:29720568 NCBI chr14:43,384,127...43,396,765
Ensembl chr14:43,384,932...43,397,125
JBrowse link
G Tmcc3 transmembrane and coiled-coil domain family 3 decreases expression ISO Bleomycin results in decreased expression of TMCC3 mRNA CTD PMID:33770205 NCBI chr 7:28,893,972...29,171,935
Ensembl chr 7:28,893,967...29,171,926
JBrowse link
G Tmem250 transmembrane protein 250 increases expression ISO Bleomycin results in increased expression of TMEM250 mRNA CTD PMID:33770205 NCBI chr 3:8,962,657...8,966,349
Ensembl chr 3:8,962,657...8,966,349
JBrowse link
G Tmem87a transmembrane protein 87A increases expression ISO Bleomycin results in increased expression of TMEM87A mRNA CTD PMID:33770205 NCBI chr 3:107,307,726...107,353,571
Ensembl chr 3:107,307,726...107,353,551
JBrowse link
G Tnc tenascin C increases expression ISO Bleomycin results in increased expression of TNC mRNA; Bleomycin results in increased expression of TNC protein CTD PMID:26345256 NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624
JBrowse link
G Tnf tumor necrosis factor multiple interactions
affects response to substance
increases expression
increases secretion
ISO
EXP
[Bleomycin co-treated with SFTPA1 protein polymorphism] results in increased expression of TNF protein; [Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein; Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]; calfactant inhibits the reaction [Bleomycin promotes the reaction [[SFTPA1 protein binds to SFTPA2 protein] which results in increased expression of TNF protein]]; Ozone inhibits the reaction [[Bleomycin co-treated with SFTPA2 protein polymorphism] results in increased expression of TNF protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of CAT protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD1 protein]; TNF protein promotes the reaction [Bleomycin results in increased expression of SOD2 protein]
TNF protein affects the susceptibility to Bleomycin
Bleomycin results in increased expression of TNF mRNA
Bleomycin results in increased expression of TNF mRNA; Bleomycin results in increased expression of TNF protein
Bleomycin results in increased secretion of TNF protein
[Bleomycin co-treated with Tobacco Smoke Pollution] results in increased expression of TNF protein; Berberine inhibits the reaction [Bleomycin results in increased expression of TNF protein]; celastrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Methylprednisolone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Phytochemicals inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; Resveratrol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Taurine inhibits the reaction [Bleomycin results in increased expression of TNF protein]
(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; 2-((dimethylamino)methyl)-9-hydroxythieno(2,3-c)isoquinolin-5(4H)-one inhibits the reaction [Bleomycin results in increased expression of TNF protein]; [SLCO2A1 gene mutant form results in increased susceptibility to Bleomycin] which results in increased expression of TNF mRNA; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPB protein; [TNF protein affects the susceptibility to Bleomycin] which affects the expression of SFTPD protein; Calcitriol inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CCR2 gene mutant form inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]; Enalapril inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; honokiol inhibits the reaction [Bleomycin results in increased expression of TNF protein]; Oils, Volatile inhibits the reaction [Bleomycin results in increased expression of TNF protein]; pirinixic acid inhibits the reaction [Bleomycin results in increased expression of TNF protein]; PPARA protein affects the reaction [Bleomycin results in increased expression of TNF protein]; Simvastatin inhibits the reaction [Bleomycin results in increased expression of TNF protein]; tetrathiomolybdate inhibits the reaction [Bleomycin results in increased expression of TNF mRNA]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein]; verlukast inhibits the reaction [Bleomycin results in increased expression of TNF protein]; zileuton inhibits the reaction [Bleomycin results in increased expression of TNF protein]
CTD PMID:8317554 PMID:8473757 PMID:11350791 PMID:12003776 PMID:14609568 More... NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A increases response to substance ISO TNFRSF1A results in increased susceptibility to Bleomycin CTD PMID:12003776 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression
increases response to substance
EXP
ISO
Bleomycin results in increased expression of TNFRSF1B protein
TNFRSF1B results in increased susceptibility to Bleomycin
CTD PMID:12003776 PMID:15371238 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
JBrowse link
G Tnfsf11 TNF superfamily member 11 decreases expression ISO Bleomycin results in decreased expression of TNFSF11 mRNA CTD PMID:29720568 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tp53 tumor protein p53 increases expression
multiple interactions
increases phosphorylation
increases response to substance
ISO Bleomycin results in increased expression of TRP53 protein
Bleomycin results in increased expression of TP53 mRNA
2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; 2-morpholin-4-yl-6-thianthren-1-yl-pyran-4-one inhibits the reaction [Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]]; Bleomycin promotes the reaction [Polyphenols results in increased expression of TP53 mRNA]; Bleomycin promotes the reaction [Resveratrol results in increased phosphorylation of TP53 protein]; Bleomycin promotes the reaction [Tea results in increased expression of TP53 mRNA]; Polyphenols promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]; Resveratrol promotes the reaction [Bleomycin results in increased phosphorylation of TP53 protein]; Tea promotes the reaction [Bleomycin results in increased expression of TP53 mRNA]
TP53 protein results in increased susceptibility to Bleomycin
CTD PMID:9683175 PMID:20135637 PMID:24933654 PMID:26800624 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Tpm1 tropomyosin 1 increases expression EXP Bleomycin results in increased expression of TPM1 protein CTD PMID:25933445 NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802
JBrowse link
G Tpm3 tropomyosin 3 increases expression EXP Bleomycin results in increased expression of TPM3 protein CTD PMID:25933445 NCBI chr 2:175,517,198...175,545,014
Ensembl chr 2:175,517,226...175,545,013
JBrowse link
G Tpm4 tropomyosin 4 increases expression EXP Bleomycin results in increased expression of TPM4 protein CTD PMID:25933445 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tppp3 tubulin polymerization-promoting protein family member 3 decreases expression EXP Bleomycin results in decreased expression of TPPP3 protein CTD PMID:25933445 NCBI chr19:33,345,897...33,349,610
Ensembl chr19:33,345,898...33,349,577
JBrowse link
G Traf2 Tnf receptor-associated factor 2 decreases expression EXP Bleomycin results in decreased expression of TRAF2 protein CTD PMID:15371238 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538
JBrowse link
G Traf3ip2 Traf3 interacting protein 2 multiple interactions ISO Calcitriol inhibits the reaction [Bleomycin results in increased phosphorylation of ACT1 protein] CTD PMID:26520185 NCBI chr20:43,011,405...43,054,654
Ensembl chr20:43,011,450...43,054,667
JBrowse link
G Trim28 tripartite motif-containing 28 increases phosphorylation ISO Bleomycin results in increased phosphorylation of TRIM28 protein CTD PMID:24933654 NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380
JBrowse link
G Trpm2 transient receptor potential cation channel, subfamily M, member 2 multiple interactions ISO TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL1 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of CXCL2 protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of IL1B protein]; TRPM2 gene mutant form inhibits the reaction [Bleomycin results in increased secretion of TNF protein] CTD PMID:26600069 NCBI chr20:10,703,568...10,753,189
Ensembl chr20:10,707,014...10,753,181
JBrowse link
G Tshr thyroid stimulating hormone receptor decreases expression EXP Bleomycin results in decreased expression of TSHR mRNA CTD PMID:15808516 NCBI chr 6:110,341,585...110,475,297
Ensembl chr 6:110,341,581...110,474,538
JBrowse link
G Tuba1c tubulin, alpha 1C decreases expression EXP Bleomycin results in decreased expression of TUBA1C protein CTD PMID:25933445 NCBI chr 7:130,192,050...130,199,655
Ensembl chr 7:130,192,016...130,199,647
Ensembl chr  X:130,192,016...130,199,647
JBrowse link
G Tubb2a tubulin, beta 2A class IIa decreases expression EXP
ISO
Bleomycin results in decreased expression of TUBB2A protein
Bleomycin results in decreased expression of TUBB2A mRNA
CTD PMID:25933445 PMID:33770205 NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
JBrowse link
G Tubb4b tubulin, beta 4B class IVb decreases expression EXP Bleomycin results in decreased expression of TUBB4B protein CTD PMID:25933445 NCBI chr 3:8,037,844...8,040,294
Ensembl chr 3:8,037,799...8,040,296
JBrowse link
G Ugcg UDP-glucose ceramide glucosyltransferase decreases expression ISO Bleomycin results in decreased expression of UGCG mRNA CTD PMID:33770205 NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
JBrowse link
G Ulk1 unc-51 like autophagy activating kinase 1 increases expression
multiple interactions
ISO Bleomycin results in increased expression of ULK1 protein modified form
Soot inhibits the reaction [Bleomycin results in increased expression of ULK1 protein modified form]
CTD PMID:31302203 NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966
JBrowse link
G Uqcrc1 ubiquinol-cytochrome c reductase core protein 1 decreases expression EXP Bleomycin results in decreased expression of UQCRC1 protein CTD PMID:25933445 NCBI chr 8:109,589,735...109,601,481
Ensembl chr 8:109,589,706...109,601,480
JBrowse link
G Uqcrh ubiquinol-cytochrome c reductase hinge protein increases expression EXP Bleomycin results in increased expression of UQCRHL protein CTD PMID:25933445 NCBI chr 5:129,545,978...129,554,173
Ensembl chr 5:129,545,984...129,554,242
JBrowse link
G Vcl vinculin decreases expression EXP Bleomycin results in decreased expression of VCL protein CTD PMID:25933445 NCBI chr15:3,265,776...3,355,586
Ensembl chr15:3,265,815...3,355,606
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression EXP Bleomycin results in increased expression of VEGFA mRNA CTD PMID:26093215 NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
JBrowse link
G Vim vimentin increases expression EXP Bleomycin results in increased expression of VIM protein CTD PMID:25933445 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xrcc1 X-ray repair cross complementing 1 affects response to substance
decreases response to substance
ISO XRCC1 gene polymorphism affects the susceptibility to Bleomycin
XRCC1 results in decreased susceptibility to Bleomycin
CTD PMID:12082022 PMID:20705543 NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701
JBrowse link
G Xrcc5 X-ray repair cross complementing 5 affects response to substance ISO XRCC5 protein affects the susceptibility to Bleomycin CTD PMID:12384553 NCBI chr 9:73,955,220...74,044,020
Ensembl chr 9:73,955,216...74,044,018
JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase decreases expression ISO Bleomycin results in decreased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:113,200,256...113,275,942
Ensembl chr 9:113,200,256...113,299,837
JBrowse link
G Ywhab tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta decreases expression EXP Bleomycin results in decreased expression of YWHAB protein CTD PMID:25933445 NCBI chr 3:152,659,663...152,682,105
Ensembl chr 3:152,659,651...152,682,105
JBrowse link
G Zfx zinc finger protein X-linked increases expression ISO Bleomycin results in increased expression of ZFX mRNA CTD PMID:33770205 NCBI chr  X:58,804,690...58,853,155
Ensembl chr  X:58,804,691...58,853,265
JBrowse link
bleomycin A5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abhd10 abhydrolase domain containing 10, depalmitoylase decreases expression ISO bleomycetin results in decreased expression of ABHD10 mRNA CTD PMID:21040473 NCBI chr11:55,081,273...55,095,044
Ensembl chr11:55,081,049...55,107,866
JBrowse link
G Alg12 ALG12, alpha-1,6-mannosyltransferase decreases expression ISO bleomycetin results in decreased expression of ALG12 mRNA CTD PMID:21040473 NCBI chr 7:119,895,112...119,909,488
Ensembl chr 7:119,895,120...119,909,458
JBrowse link
G Amacr alpha-methylacyl-CoA racemase decreases expression ISO bleomycetin results in decreased expression of AMACR mRNA CTD PMID:21040473 NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255
JBrowse link
G Arf4 ADP-ribosylation factor 4 decreases expression ISO bleomycetin results in decreased expression of ARF4 mRNA CTD PMID:21040473 NCBI chr16:1,896,692...1,913,267
Ensembl chr16:1,896,546...1,913,261
JBrowse link
G B2m beta-2 microglobulin decreases expression ISO bleomycetin results in decreased expression of B2M mRNA CTD PMID:21040473 NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766
JBrowse link
G Bmp2 bone morphogenetic protein 2 increases expression ISO bleomycetin results in increased expression of BMP2 mRNA CTD PMID:21040473 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Ca9 carbonic anhydrase 9 increases expression
multiple interactions
decreases response to substance
ISO bleomycetin results in increased expression of CA9 mRNA; bleomycetin results in increased expression of CA9 protein
CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein]
CA9 protein results in decreased susceptibility to bleomycetin
CTD PMID:21040473 NCBI chr 5:57,763,234...57,769,838
Ensembl chr 5:57,763,206...57,769,838
JBrowse link
G Casd1 CAS1 domain containing 1 decreases expression ISO bleomycetin results in decreased expression of CASD1 mRNA CTD PMID:21040473 NCBI chr 4:32,658,888...32,739,224
Ensembl chr 4:32,658,748...32,739,202
JBrowse link
G Casp1 caspase 1 decreases expression ISO bleomycetin results in decreased expression of CASP1 mRNA CTD PMID:21040473 NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO Acetazolamide promotes the reaction [bleomycetin results in increased activity of CASP3 protein]; CA9 protein inhibits the reaction [bleomycetin results in increased activity of CASP3 protein] CTD PMID:21040473 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cdhr5 cadherin-related family member 5 decreases expression ISO bleomycetin results in decreased expression of CDHR5 mRNA CTD PMID:21040473 NCBI chr 1:196,373,110...196,381,609
Ensembl chr 1:196,373,112...196,381,543
JBrowse link
G Cox7b cytochrome c oxidase subunit 7B decreases expression ISO bleomycetin results in decreased expression of COX7B mRNA CTD PMID:21040473 NCBI chr  X:71,083,486...71,089,733
Ensembl chr  X:71,083,456...71,089,732
JBrowse link
G Cul4a cullin 4A increases expression ISO bleomycetin results in increased expression of CUL4A mRNA CTD PMID:21040473 NCBI chr16:76,385,298...76,422,316
Ensembl chr16:76,384,546...76,422,330
JBrowse link
G Ddit4 DNA-damage-inducible transcript 4 increases expression ISO bleomycetin results in increased expression of DDIT4 mRNA CTD PMID:21040473 NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105
JBrowse link
G Dhcr24 24-dehydrocholesterol reductase decreases expression ISO bleomycetin results in decreased expression of DHCR24 mRNA CTD PMID:21040473 NCBI chr 5:121,344,637...121,368,853
Ensembl chr 5:121,344,575...121,371,137
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 decreases expression ISO bleomycetin results in decreased expression of DKK1 mRNA CTD PMID:21040473 NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202
JBrowse link
G Dpysl2 dihydropyrimidinase-like 2 decreases expression ISO bleomycetin results in decreased expression of DPYSL2 mRNA CTD PMID:21040473 NCBI chr15:41,005,551...41,111,724
Ensembl chr15:41,005,551...41,111,829
JBrowse link
G Ehd4 EH-domain containing 4 increases expression ISO bleomycetin results in increased expression of EHD4 mRNA CTD PMID:21040473 NCBI chr 3:107,058,191...107,121,985
Ensembl chr 3:107,058,958...107,122,002
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 increases expression ISO bleomycetin results in increased expression of EIF4G1 mRNA CTD PMID:21040473 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Emc4 ER membrane protein complex subunit 4 decreases expression ISO bleomycetin results in decreased expression of EMC4 mRNA CTD PMID:21040473 NCBI chr 3:99,169,711...99,174,730
Ensembl chr 3:99,169,711...99,174,729
JBrowse link
G Emc7 ER membrane protein complex subunit 7 decreases expression ISO bleomycetin results in decreased expression of EMC7 mRNA CTD PMID:21040473 NCBI chr 3:99,263,933...99,274,365
Ensembl chr 3:99,263,980...99,274,360
JBrowse link
G Eno2 enolase 2 increases expression ISO bleomycetin results in increased expression of ENO2 mRNA CTD PMID:21040473 NCBI chr 4:157,572,085...157,580,971
Ensembl chr 4:157,572,088...157,580,980
JBrowse link
G Fbn2 fibrillin 2 decreases expression ISO bleomycetin results in decreased expression of FBN2 mRNA CTD PMID:21040473 NCBI chr18:51,499,737...51,703,976
Ensembl chr18:51,499,737...51,703,976
JBrowse link
G Fkbp1a FKBP prolyl isomerase 1A increases expression ISO bleomycetin results in increased expression of FKBP1A mRNA CTD PMID:21040473 NCBI chr 3:140,040,359...140,060,107
Ensembl chr 3:140,040,278...140,060,743
JBrowse link
G Fkbp9 FKBP prolyl isomerase 9 decreases expression ISO bleomycetin results in decreased expression of FKBP9 mRNA CTD PMID:21040473 NCBI chr 4:86,106,256...86,156,723
Ensembl chr 4:86,106,282...86,156,721
JBrowse link
G Frs3 fibroblast growth factor receptor substrate 3 increases expression ISO bleomycetin results in increased expression of FRS3 mRNA CTD PMID:21040473 NCBI chr 9:13,288,559...13,297,285
Ensembl chr 9:13,288,667...13,295,382
JBrowse link
G Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 decreases expression ISO bleomycetin results in decreased expression of GALNT10 mRNA CTD PMID:21040473 NCBI chr10:41,821,216...41,967,618
Ensembl chr10:41,820,158...41,967,013
JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression ISO bleomycetin results in increased expression of GCLC mRNA CTD PMID:21040473 NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
JBrowse link
G Gng11 G protein subunit gamma 11 decreases expression ISO bleomycetin results in decreased expression of GNG11 mRNA CTD PMID:21040473 NCBI chr 4:32,023,003...32,028,443
Ensembl chr 4:32,023,003...32,028,442
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO bleomycetin results in decreased expression of GSTK1 mRNA CTD PMID:21040473 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G H2bc12 H2B clustered histone 12 decreases expression ISO bleomycetin results in decreased expression of H2BC12 mRNA CTD PMID:21040473 NCBI chr17:42,485,746...42,486,126 JBrowse link
G Hnrnpab heterogeneous nuclear ribonucleoprotein A/B increases expression ISO bleomycetin results in increased expression of HNRNPAB mRNA CTD PMID:21040473 NCBI chr10:35,857,040...35,862,935
Ensembl chr10:35,857,041...35,863,344
JBrowse link
G Hoxb7 homeo box B7 decreases expression ISO bleomycetin results in decreased expression of HOXB7 mRNA CTD PMID:21040473 NCBI chr10:81,252,616...81,256,034
Ensembl chr10:81,252,553...81,256,034
JBrowse link
G Hsph1 heat shock protein family H (Hsp110) member 1 decreases expression ISO bleomycetin results in decreased expression of HSPH1 mRNA CTD PMID:21040473 NCBI chr12:5,390,916...5,410,224
Ensembl chr12:5,390,922...5,410,224
JBrowse link
G Idh3a isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha decreases expression ISO bleomycetin results in decreased expression of IDH3A mRNA CTD PMID:21040473 NCBI chr 8:54,971,694...54,991,085
Ensembl chr 8:54,971,740...54,991,084
JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 decreases expression ISO bleomycetin results in decreased expression of IDI1 mRNA CTD PMID:21040473 NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
JBrowse link
G Itga5 integrin subunit alpha 5 increases expression ISO bleomycetin results in increased expression of ITGA5 mRNA CTD PMID:21040473 NCBI chr 7:134,478,963...134,502,837
Ensembl chr 7:134,478,968...134,502,837
JBrowse link
G Itgb5 integrin subunit beta 5 increases expression ISO bleomycetin results in increased expression of ITGB5 mRNA CTD PMID:21040473 NCBI chr11:66,828,428...66,944,231
Ensembl chr11:66,829,285...66,944,472
JBrowse link
G Itpr1 inositol 1,4,5-trisphosphate receptor, type 1 increases expression ISO bleomycetin results in increased expression of ITPR1 mRNA CTD PMID:21040473 NCBI chr 4:141,187,377...141,554,240
Ensembl chr 4:141,187,418...141,510,491
JBrowse link
G Kat6b lysine acetyltransferase 6B decreases expression ISO bleomycetin results in decreased expression of KAT6B mRNA CTD PMID:21040473 NCBI chr15:2,638,885...2,811,977
Ensembl chr15:2,639,200...2,812,316
JBrowse link
G Lypd3 Ly6/Plaur domain containing 3 increases expression ISO bleomycetin results in increased expression of LYPD3 mRNA CTD PMID:21040473 NCBI chr 1:80,226,449...80,230,901
Ensembl chr 1:80,226,449...80,230,901
JBrowse link
G Mageb2 MAGE family member B2 decreases expression ISO bleomycetin results in decreased expression of MAGEB2 mRNA CTD PMID:21040473 NCBI chr  X:50,827,538...50,833,272
Ensembl chr  X:50,827,563...50,833,151
JBrowse link
G Man1b1 mannosidase, alpha, class 1B, member 1 increases expression ISO bleomycetin results in increased expression of MAN1B1 mRNA CTD PMID:21040473 NCBI chr 3:8,143,877...8,165,007
Ensembl chr 3:8,143,381...8,165,006
JBrowse link
G Mcm2 minichromosome maintenance complex component 2 increases expression ISO bleomycetin results in increased expression of MCM2 mRNA CTD PMID:21040473 NCBI chr 4:121,346,434...121,360,962
Ensembl chr 4:121,346,434...121,360,847
JBrowse link
G Med11 mediator complex subunit 11 decreases expression ISO bleomycetin results in decreased expression of MED11 mRNA CTD PMID:21040473 NCBI chr10:55,164,304...55,166,134
Ensembl chr10:55,164,326...55,166,533
JBrowse link
G Metrn meteorin, glial cell differentiation regulator increases expression ISO bleomycetin results in increased expression of METRN mRNA CTD PMID:21040473 NCBI chr10:14,816,684...14,818,702
Ensembl chr10:14,816,572...14,818,701
JBrowse link
G Mt2A metallothionein 2A increases expression ISO bleomycetin results in increased expression of MT2A mRNA; bleomycetin results in increased expression of MT2A protein CTD PMID:21040473 NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor increases expression ISO bleomycetin results in increased expression of MYC mRNA CTD PMID:21040473 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 increases expression ISO bleomycetin results in increased expression of NCBP2 mRNA CTD PMID:21040473 NCBI chr11:68,821,026...68,829,863
Ensembl chr11:68,817,740...68,851,885
JBrowse link
G Ndrg1 N-myc downstream regulated 1 increases expression ISO bleomycetin results in increased expression of NDRG1 mRNA CTD PMID:21040473 NCBI chr 7:98,684,487...98,725,869
Ensembl chr 7:98,684,487...98,725,880
JBrowse link
G Nop10 NOP10 ribonucleoprotein decreases expression ISO bleomycetin results in decreased expression of NOLA3 mRNA CTD PMID:21040473 NCBI chr 3:99,066,857...99,067,942
Ensembl chr 3:99,066,857...99,067,942
JBrowse link
G Nop56 NOP56 ribonucleoprotein increases expression ISO bleomycetin results in increased expression of NOP56 mRNA CTD PMID:21040473 NCBI chr 3:117,476,963...117,481,847
Ensembl chr 3:117,477,053...117,481,841
JBrowse link
G Nrdc nardilysin convertase decreases expression ISO bleomycetin results in decreased expression of NRDC mRNA CTD PMID:21040473 NCBI chr 5:123,755,807...123,818,910
Ensembl chr 5:123,755,806...123,818,595
JBrowse link
G P4ha1 prolyl 4-hydroxylase subunit alpha 1 increases expression ISO bleomycetin results in increased expression of P4HA1 mRNA CTD PMID:21040473 NCBI chr20:27,302,046...27,352,098
Ensembl chr20:27,302,141...27,352,786
JBrowse link
G Parn poly(A)-specific ribonuclease increases expression ISO bleomycetin results in increased expression of PARN mRNA CTD PMID:21040473 NCBI chr10:1,410,636...1,548,573
Ensembl chr10:1,410,642...1,548,560
JBrowse link
G Pdgfa platelet derived growth factor subunit A decreases expression ISO bleomycetin results in decreased expression of PDGFA mRNA CTD PMID:21040473 NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
JBrowse link
G Pgd phosphogluconate dehydrogenase decreases expression ISO bleomycetin results in decreased expression of PGD mRNA CTD PMID:21040473 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Pgrmc2 progesterone receptor membrane component 2 increases expression ISO bleomycetin results in increased expression of PGRMC2 mRNA CTD PMID:21040473 NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
JBrowse link
G Pkn3 protein kinase N3 decreases expression ISO bleomycetin results in decreased expression of PKN3 mRNA CTD PMID:21040473 NCBI chr 3:13,350,082...13,363,572
Ensembl chr 3:13,335,041...13,363,567
JBrowse link
G Ppp2r2b protein phosphatase 2, regulatory subunit B, beta increases expression ISO bleomycetin results in increased expression of PPP2R2B mRNA CTD PMID:21040473 NCBI chr18:34,653,716...35,080,889
Ensembl chr18:34,653,721...35,081,025
JBrowse link
G Pqbp1 polyglutamine binding protein 1 decreases expression ISO bleomycetin results in decreased expression of PQBP1 mRNA CTD PMID:21040473 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087
JBrowse link
G Ptges prostaglandin E synthase decreases expression ISO bleomycetin results in decreased expression of PTGES mRNA CTD PMID:21040473 NCBI chr 3:14,177,892...14,189,236 JBrowse link
G Rab31 RAB31, member RAS oncogene family increases expression ISO bleomycetin results in increased expression of RAB31 mRNA CTD PMID:21040473 NCBI chr 9:105,246,712...105,382,973
Ensembl chr 9:105,246,709...105,381,253
JBrowse link
G Rbp4 retinol binding protein 4 decreases expression ISO bleomycetin results in decreased expression of RBP4 mRNA CTD PMID:21040473 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Rps4x ribosomal protein S4, X-linked decreases expression ISO bleomycetin results in decreased expression of RPS4X mRNA CTD PMID:21040473 NCBI chr  X:67,298,522...67,302,965
Ensembl chr  X:67,298,525...67,303,019
JBrowse link
G Rsl1d1 ribosomal L1 domain containing 1 increases expression ISO bleomycetin results in increased expression of RSL1D1 mRNA CTD PMID:21040473 NCBI chr10:4,424,868...4,436,753
Ensembl chr10:4,397,821...4,439,593
JBrowse link
G Ruvbl1 RuvB-like AAA ATPase 1 increases expression ISO bleomycetin results in increased expression of RUVBL1 mRNA CTD PMID:21040473 NCBI chr 4:120,932,486...120,967,400
Ensembl chr 4:120,932,417...121,029,384
JBrowse link
G Scnn1a sodium channel epithelial 1 subunit alpha decreases expression ISO bleomycetin results in decreased expression of SCNN1A mRNA CTD PMID:21040473 NCBI chr 4:158,122,962...158,146,184
Ensembl chr 4:158,122,962...158,146,181
JBrowse link
G Sdc4 syndecan 4 increases expression ISO bleomycetin results in increased expression of SDC4 mRNA CTD PMID:21040473 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580
JBrowse link
G Sfpq splicing factor proline and glutamine rich increases expression ISO bleomycetin results in increased expression of SFPQ mRNA CTD PMID:21040473 NCBI chr 5:139,338,034...139,353,476
Ensembl chr 5:139,338,075...139,353,472
JBrowse link
G Sgk1 serum/glucocorticoid regulated kinase 1 increases expression ISO bleomycetin results in increased expression of SGK1 mRNA CTD PMID:21040473 NCBI chr 1:22,980,257...23,098,122
Ensembl chr 1:22,980,261...23,098,283
JBrowse link
G Sltm SAFB-like, transcription modulator decreases expression ISO bleomycetin results in decreased expression of SLTM mRNA CTD PMID:21040473 NCBI chr 8:71,215,995...71,261,821
Ensembl chr 8:71,216,612...71,261,825
JBrowse link
G Socs3 suppressor of cytokine signaling 3 increases expression ISO bleomycetin results in increased expression of SOCS3 mRNA CTD PMID:21040473 NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
JBrowse link
G Srxn1 sulfiredoxin 1 increases expression ISO bleomycetin results in increased expression of SRXN1 mRNA CTD PMID:21040473 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Tcp1 t-complex 1 decreases expression ISO bleomycetin results in decreased expression of TCP1 mRNA CTD PMID:21040473 NCBI chr 1:47,829,061...47,836,809
Ensembl chr 1:47,828,652...47,836,839
JBrowse link
G Tma7 translation machinery associated 7 homolog decreases expression ISO bleomycetin results in decreased expression of TMA7 mRNA CTD PMID:21040473 NCBI chr 8:109,726,213...109,730,902
Ensembl chr 8:109,726,196...109,735,474
JBrowse link
G Tmem230 transmembrane protein 230 increases expression ISO bleomycetin results in increased expression of TMEM230 mRNA CTD PMID:21040473 NCBI chr 3:119,473,109...119,497,617
Ensembl chr 3:119,480,735...119,497,614
JBrowse link
G Tpm4 tropomyosin 4 increases expression ISO bleomycetin results in increased expression of TPM4 mRNA CTD PMID:21040473 NCBI chr16:17,684,415...17,698,456
Ensembl chr16:17,683,195...17,705,984
JBrowse link
G Tsc22d1 TSC22 domain family, member 1 increases expression ISO bleomycetin results in increased expression of TSC22D1 mRNA CTD PMID:21040473 NCBI chr15:51,750,489...51,850,958
Ensembl chr15:51,749,510...51,850,958
JBrowse link
G Upp1 uridine phosphorylase 1 decreases expression ISO bleomycetin results in decreased expression of UPP1 mRNA CTD PMID:21040473 NCBI chr14:83,809,495...83,829,299
Ensembl chr14:83,809,960...83,829,462
JBrowse link
G Usp37 ubiquitin specific peptidase 37 decreases expression ISO bleomycetin results in decreased expression of USP37 mRNA CTD PMID:21040473 NCBI chr 9:76,018,863...76,118,732
Ensembl chr 9:76,018,991...76,084,044
JBrowse link
G Uxt ubiquitously-expressed, prefoldin-like chaperone decreases expression ISO bleomycetin results in decreased expression of UXT mRNA CTD PMID:21040473 NCBI chr  X:1,126,110...1,138,670
Ensembl chr  X:1,126,162...1,138,663
JBrowse link
G Zfp541 zinc finger protein 541 decreases expression ISO bleomycetin results in decreased expression of ZNF541 mRNA CTD PMID:21040473 NCBI chr 1:76,750,236...76,786,567
Ensembl chr 1:76,750,236...76,786,567
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19800
    role 19751
      biological role 19751
        antimicrobial agent 17472
          peptide antibiotic 1685
            chelate-forming peptide 611
              bleomycin + 611
              phleomycin D1 + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19800
    subatomic particle 19799
      composite particle 19799
        hadron 19799
          baryon 19799
            nucleon 19799
              atomic nucleus 19799
                atom 19799
                  main group element atom 19698
                    p-block element atom 19698
                      carbon group element atom 19619
                        carbon atom 19609
                          organic molecular entity 19609
                            organic group 18718
                              organic divalent group 18702
                                organodiyl group 18702
                                  carbonyl group 18651
                                    carbonyl compound 18651
                                      carboxylic acid 18346
                                        carboacyl group 17469
                                          univalent carboacyl group 17469
                                            carbamoyl group 17285
                                              carboxamide 17285
                                                peptide 9455
                                                  peptide antibiotic 1685
                                                    chelate-forming peptide 611
                                                      bleomycin + 611
                                                      phleomycin D1 + 0
paths to the root