Ehd2 (EH-domain containing 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ehd2 (EH-domain containing 2) Rattus norvegicus
Analyze
Symbol: Ehd2
Name: EH-domain containing 2
RGD ID: 1560856
Description: Predicted to enable identical protein binding activity and protein domain specific binding activity. Predicted to be involved in several processes, including plasma membrane tubulation; positive regulation of endocytic recycling; and positive regulation of myoblast fusion. Predicted to act upstream of or within cortical actin cytoskeleton organization. Predicted to be located in several cellular components, including caveola; intercellular bridge; and microtubule cytoskeleton. Predicted to be active in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Orthologous to human EHD2 (EH domain containing 2); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane; 2,3,7,8-tetrachlorodibenzodioxine; 3',5'-cyclic AMP.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EH domain-containing protein 2; MGEPS; putative eps protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8185,767,757 - 85,786,974 (-)NCBIGRCr8
mRatBN7.2176,639,568 - 76,658,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,637,482 - 76,658,783 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,015,477 - 82,032,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,579,536 - 90,596,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,770,617 - 83,787,829 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0177,847,599 - 77,865,870 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,847,600 - 77,865,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,112,279 - 79,130,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,292,179 - 76,310,584 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera171,130,719 - 71,149,079 (-)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3',5'-cyclic AMP  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
acetamide  (EXP)
actinomycin D  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
diethylstilbestrol  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenamidone  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
ivermectin  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
Mesaconitine  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP)
Nutlin-3  (ISO)
oxaliplatin  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
Soman  (EXP)
succimer  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
topotecan  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
Triptolide  (EXP)
tris(2-butoxyethyl) phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:2227441   PMID:11423532   PMID:14676205   PMID:15182197   PMID:15247266   PMID:15489334   PMID:17233914   PMID:17914359   PMID:19056867   PMID:20489164   PMID:21177873   PMID:24013648  
PMID:24508342   PMID:24664435   PMID:29133341   PMID:33450132  


Genomics

Comparative Map Data
Ehd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8185,767,757 - 85,786,974 (-)NCBIGRCr8
mRatBN7.2176,639,568 - 76,658,747 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl176,637,482 - 76,658,783 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx182,015,477 - 82,032,689 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0190,579,536 - 90,596,748 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0183,770,617 - 83,787,829 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0177,847,599 - 77,865,870 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl177,847,600 - 77,865,870 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0179,112,279 - 79,130,529 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,292,179 - 76,310,584 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera171,130,719 - 71,149,079 (-)NCBICelera
Cytogenetic Map1q21NCBI
EHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381947,713,422 - 47,743,134 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1947,713,422 - 47,743,134 (+)EnsemblGRCh38hg38GRCh38
GRCh371948,216,679 - 48,246,391 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361952,908,502 - 52,938,203 (+)NCBINCBI36Build 36hg18NCBI36
Build 341952,908,501 - 52,938,202NCBI
Celera1945,022,299 - 45,052,093 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1944,643,202 - 44,673,032 (+)NCBIHuRef
CHM1_11948,218,935 - 48,248,702 (+)NCBICHM1_1
T2T-CHM13v2.01950,544,240 - 50,573,946 (+)NCBIT2T-CHM13v2.0
Ehd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39715,680,883 - 15,701,402 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl715,680,883 - 15,701,492 (-)EnsemblGRCm39 Ensembl
GRCm38715,946,963 - 15,967,535 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl715,946,958 - 15,967,567 (-)EnsemblGRCm38mm10GRCm38
MGSCv37716,534,336 - 16,552,884 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36715,107,509 - 15,126,057 (-)NCBIMGSCv36mm8
Celera713,147,692 - 13,166,237 (-)NCBICelera
Cytogenetic Map7A2NCBI
cM Map78.65NCBI
Ehd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555741,490,877 - 1,503,943 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555741,490,877 - 1,503,651 (+)NCBIChiLan1.0ChiLan1.0
EHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22053,866,762 - 53,896,564 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11955,736,790 - 55,766,387 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01944,707,747 - 44,737,370 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11953,361,831 - 53,390,877 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1953,365,510 - 53,389,159 (+)Ensemblpanpan1.1panPan2
EHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11108,317,471 - 108,336,032 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1108,318,680 - 108,345,885 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1107,799,663 - 107,818,190 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01108,843,517 - 108,862,065 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1108,843,515 - 108,862,033 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11108,511,223 - 108,529,700 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01108,155,771 - 108,174,509 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01109,023,931 - 109,042,491 (-)NCBIUU_Cfam_GSD_1.0
Ehd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934919,698,492 - 19,713,548 (+)NCBIHiC_Itri_2
SpeTri2.0NW_0049366641,316,621 - 1,331,678 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl653,423,563 - 53,443,224 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1653,423,489 - 53,442,007 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2648,953,673 - 48,972,126 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1641,034,263 - 41,054,340 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl641,034,274 - 41,056,401 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607320,787,175 - 20,807,886 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ehd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248326,155,839 - 6,168,628 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248326,156,051 - 6,168,638 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ehd2
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:163
Count of miRNA genes:123
Interacting mature miRNAs:128
Transcripts:ENSRNOT00000017353
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
4889929Bss87Bone structure and strength QTL 876.7tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)15389511782174945Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
4889919Bss86Bone structure and strength QTL 864.1tibia area (VT:1000281)tibia midshaft total cross-sectional area (CMO:0001715)15389511782174945Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat

Markers in Region
AI555194  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2176,640,499 - 76,640,679 (+)MAPPERmRatBN7.2
Rnor_6.0177,847,621 - 77,847,800NCBIRnor6.0
Rnor_5.0179,112,301 - 79,112,480UniSTSRnor5.0
RGSC_v3.4176,292,201 - 76,292,380UniSTSRGSC3.4
Celera171,130,741 - 71,130,920UniSTS
Cytogenetic Map1q21UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017353   ⟹   ENSRNOP00000017353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl176,637,482 - 76,658,783 (-)Ensembl
Rnor_6.0 Ensembl177,847,600 - 77,865,870 (-)Ensembl
RefSeq Acc Id: NM_001024897   ⟹   NP_001020068
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,768,666 - 85,786,943 (-)NCBI
mRatBN7.2176,640,478 - 76,658,747 (-)NCBI
Rnor_6.0177,847,599 - 77,865,870 (-)NCBI
Rnor_5.0179,112,279 - 79,130,529 (-)NCBI
RGSC_v3.4176,292,179 - 76,310,584 (-)RGD
Celera171,130,719 - 71,149,079 (-)RGD
Sequence:
RefSeq Acc Id: XM_039081636   ⟹   XP_038937564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8185,767,757 - 85,786,974 (-)NCBI
mRatBN7.2176,639,568 - 76,656,699 (-)NCBI
RefSeq Acc Id: NP_001020068   ⟸   NM_001024897
- UniProtKB: Q4V8H8 (UniProtKB/Swiss-Prot),   A6J888 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017353   ⟸   ENSRNOT00000017353
RefSeq Acc Id: XP_038937564   ⟸   XM_039081636
- Peptide Label: isoform X1
- UniProtKB: Q4V8H8 (UniProtKB/Swiss-Prot),   A6J888 (UniProtKB/TrEMBL)
Protein Domains
Dynamin-type G   EF-hand   EH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4V8H8-F1-model_v2 AlphaFold Q4V8H8 1-543 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689723
Promoter ID:EPDNEW_R247
Type:multiple initiation site
Name:Ehd2_1
Description:EH-domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0177,865,901 - 77,865,961EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560856 AgrOrtholog
BioCyc Gene G2FUF-60629 BioCyc
Ensembl Genes ENSRNOG00000011346 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055016818 UniProtKB/Swiss-Prot
  ENSRNOG00060020203 UniProtKB/Swiss-Prot
  ENSRNOG00065033793 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017353.6 UniProtKB/Swiss-Prot
  ENSRNOT00055028576 UniProtKB/Swiss-Prot
  ENSRNOT00060034967 UniProtKB/Swiss-Prot
  ENSRNOT00065058030 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.268.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7446444 IMAGE-MGC_LOAD
InterPro DUF5600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynamin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EHD_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_DYNAMIN_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:361512 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:114425 IMAGE-MGC_LOAD
NCBI Gene 361512 ENTREZGENE
PANTHER EH DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EPIDERMAL GROWTH FACTOR RECEPTOR PATHWAY SUBSTRATE CLONE 15, ISOFORM A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF5600 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Dynamin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF-hand_4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EHD_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ehd2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_DYNAMIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS50031 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000011346 RatGTEx
  ENSRNOG00055016818 RatGTEx
  ENSRNOG00060020203 RatGTEx
  ENSRNOG00065033793 RatGTEx
SMART SM00027 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EF-hand UniProtKB/TrEMBL
  P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
  SSF47473 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A6J888 ENTREZGENE, UniProtKB/TrEMBL
  EHD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Ehd2  EH-domain containing 2  MGEPS  putative eps protein  Symbol and Name updated 1299863 APPROVED
2006-02-09 MGEPS  putative eps protein      Symbol and Name status set to provisional 70820 PROVISIONAL