elemental selenium - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	elemental selenium	go back to main search page
Accession:	CHEBI:36904	browse the term
Synonyms:	xref:	CAS:7782-49-2
	xref_mesh:	MESH:D012643

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Genes (1646)

elemental selenium

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-2-macroglobulin

increases expression
multiple interactions

Selenium results in increased expression of A2M mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of A2M mRNA]; Selenium promotes the reaction [T-2 Toxin results in decreased expression of A2M protein]

PMID:18997278 PMID:21144892

NCBI chr12:9,067,708...9,116,229
Ensembl chr12:9,067,664...9,116,229

G

angio associated migratory cell protein

increases expression

Selenium results in increased expression of AAMP mRNA

NCBI chr 2:218,264,129...218,270,137
Ensembl chr 2:218,264,129...218,270,178

G

aminoadipate-semialdehyde synthase

decreases expression
multiple interactions

Selenium results in decreased expression of AASS mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AASS mRNA

NCBI chr 7:122,073,549...122,144,249
Ensembl chr 7:122,064,583...122,144,308

G

apoptosis antagonizing transcription factor

increases expression

Selenium results in increased expression of AATF mRNA

NCBI chr17:36,948,954...37,056,871
Ensembl chr17:36,948,925...37,056,871

G

ATP binding cassette subfamily A member 7

increases expression

Selenium results in increased expression of ABCA7 mRNA

NCBI chr19:1,040,107...1,065,572
Ensembl chr19:1,039,997...1,065,572

G

ATP binding cassette subfamily C member 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ABCC2 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCC2 mRNA]

PMID:11444866 PMID:36464106

NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594

G

ATP binding cassette subfamily F member 3

increases expression

Selenium results in increased expression of ABCF3 mRNA

NCBI chr 3:184,186,199...184,194,005
Ensembl chr 3:184,186,095...184,194,012

G

ATP binding cassette subfamily G member 2 (JR blood group)

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of ABCG2 mRNA]

NCBI chr 4:88,090,264...88,231,626
Ensembl chr 4:88,090,150...88,231,628

G

ATP binding cassette subfamily G member 5

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of ABCG5 mRNA]

NCBI chr 2:43,806,211...43,839,231
Ensembl chr 2:43,812,472...43,838,865

G

abhydrolase domain containing 17A, depalmitoylase

increases expression

Selenium results in increased expression of ABHD17A mRNA

NCBI chr19:1,876,810...1,885,496
Ensembl chr19:1,876,810...1,885,496

G

abhydrolase domain containing 2, acylglycerol lipase

increases expression

Selenium results in increased expression of ABHD2 mRNA

NCBI chr15:89,040,998...89,202,355
Ensembl chr15:89,087,459...89,202,355

G

ABR activator of RhoGEF and GTPase

increases expression

Selenium results in increased expression of ABR mRNA

NCBI chr17:1,003,519...1,229,722
Ensembl chr17:1,003,519...1,229,738

G

acetyl-CoA acyltransferase 2

increases expression

Selenium results in increased expression of ACAA2 mRNA

NCBI chr18:49,782,164...49,813,533
Ensembl chr18:49,782,164...49,813,953

G

acyl-CoA dehydrogenase short chain

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ACADS mRNA
Selenium results in increased expression of ACADS mRNA

NCBI chr12:120,725,826...120,740,008
Ensembl chr12:120,725,774...120,740,008

G

acetylcholinesterase (Yt blood group)

multiple interactions

[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium co-treated with Zinc] results in increased activity of ACHE protein; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in increased activity of ACHE protein; [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in decreased activity of ACHE protein]

PMID:20688495 PMID:37415728

NCBI chr 7:100,889,994...100,896,994
Ensembl chr 7:100,889,994...100,896,974

G

apoptotic chromatin condensation inducer 1

increases expression

Selenium results in increased expression of ACIN1 mRNA

NCBI chr14:23,058,564...23,095,614
Ensembl chr14:23,058,564...23,095,614

G

aconitase 2

increases expression

Selenium results in increased expression of ACO2 mRNA

NCBI chr22:41,469,117...41,528,974
Ensembl chr22:41,447,830...41,529,273

G

acyl-CoA thioesterase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ACOT2 mRNA
Selenium results in increased expression of ACOT2 mRNA

NCBI chr14:73,567,620...73,575,658
Ensembl chr14:73,567,620...73,575,658

G

acid phosphatase 1

decreases expression

Selenium results in decreased expression of ACP1 mRNA

NCBI chr 2:264,947...278,283
Ensembl chr 2:264,140...278,283

G

acyl-CoA synthetase long chain family member 4

multiple interactions

[2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] inhibits the reaction [Aflatoxin B1 results in increased expression of ACSL4 protein]; [2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in decreased expression of ACSL4 protein

NCBI chr X:109,641,335...109,733,257
Ensembl chr X:109,624,244...109,733,403

G

actin beta

increases expression

Selenium results in increased expression of ACTB mRNA

NCBI chr 7:5,527,148...5,530,601
Ensembl chr 7:5,526,409...5,563,902

G

actin gamma 1

increases expression

Selenium results in increased expression of ACTG1 mRNA

NCBI chr17:81,509,971...81,512,799
Ensembl chr17:81,509,413...81,523,847

G

actinin alpha 1

increases expression

Selenium results in increased expression of ACTN1 mRNA

NCBI chr14:68,874,128...68,979,302
Ensembl chr14:68,874,128...68,979,440

G

actinin alpha 4

increases expression

Selenium results in increased expression of ACTN4 mRNA

NCBI chr19:38,647,649...38,731,589
Ensembl chr19:38,647,649...38,731,589

G

actin related protein 1A

increases expression

Selenium results in increased expression of ACTR1A mRNA

NCBI chr10:102,479,229...102,502,712
Ensembl chr10:102,461,881...102,502,712

G

actin related protein 1B

increases expression

Selenium results in increased expression of ACTR1B mRNA

NCBI chr 2:97,655,939...97,664,044
Ensembl chr 2:97,655,939...97,664,044

G

aminoacylase 1

increases expression

Selenium results in increased expression of ACY1 mRNA

NCBI chr 3:51,983,535...51,989,197
Ensembl chr 3:51,983,340...51,989,197

G

ADAM metallopeptidase with thrombospondin type 1 motif 5

decreases expression

Selenium results in decreased expression of ADAMTS5 mRNA

NCBI chr21:26,917,922...26,967,088
Ensembl chr21:26,917,922...26,967,088

G

ArfGAP with dual PH domains 1

increases expression

Selenium results in increased expression of ADAP1 mRNA

NCBI chr 7:897,900...955,407
Ensembl chr 7:897,900...955,407

G

adenylate cyclase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ADCY2 mRNA
Selenium results in decreased expression of ADCY2 mRNA

NCBI chr 5:7,396,138...7,830,081
Ensembl chr 5:7,396,138...7,830,081

G

adenylate cyclase 6

increases expression

Selenium results in increased expression of ADCY6 mRNA

NCBI chr12:48,766,194...48,789,974
Ensembl chr12:48,766,194...48,789,089

G

adducin 1

increases expression

Selenium results in increased expression of ADD1 mRNA

NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076

G

adducin 3

decreases expression

Selenium results in decreased expression of ADD3 mRNA

NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565

G

adhesion G protein-coupled receptor B1

increases expression

Selenium results in increased expression of ADGRB1 mRNA

NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009

G

alcohol dehydrogenase 1B (class I), beta polypeptide

decreases expression

Selenium results in decreased expression of ADH1B mRNA

NCBI chr 4:99,304,971...99,321,401
Ensembl chr 4:99,304,971...99,321,401

G

adipose secreted signaling protein

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ADISSP mRNA

NCBI chr20:3,753,508...3,768,388
Ensembl chr20:3,753,508...3,767,781

G

adenosine A2a receptor

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of ADORA2A mRNA

NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357

G

adrenoceptor alpha 2C

increases expression

Selenium results in increased expression of ADRA2C mRNA

NCBI chr 4:3,766,385...3,768,526
Ensembl chr 4:3,766,348...3,768,526

G

ADRM1 26S proteasome ubiquitin receptor

increases expression

Selenium results in increased expression of ADRM1 mRNA

NCBI chr20:62,302,896...62,308,862
Ensembl chr20:62,302,093...62,308,862

G

AE binding protein 2

decreases methylation

Selenium results in decreased methylation of AEBP2 gene

NCBI chr12:19,404,072...19,522,227
Ensembl chr12:19,404,045...19,720,801

G

1-acylglycerol-3-phosphate O-acyltransferase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AGPAT2 mRNA
Selenium results in increased expression of AGPAT2 mRNA

NCBI chr 9:136,673,143...136,687,457
Ensembl chr 9:136,673,143...136,687,457

G

agrin

increases expression

Selenium results in increased expression of AGRN mRNA

NCBI chr 1:1,020,120...1,056,116
Ensembl chr 1:1,020,120...1,056,118

G

aminoacyl tRNA synthetase complex interacting multifunctional protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of AIMP1 mRNA
Selenium results in decreased expression of AIMP1 mRNA

NCBI chr 4:106,315,544...106,349,456
Ensembl chr 4:106,315,544...106,349,456

G

aryl hydrocarbon receptor interacting protein

increases expression

Selenium results in increased expression of AIP mRNA

NCBI chr11:67,483,026...67,491,103
Ensembl chr11:67,468,174...67,491,154

G

adenylate kinase 1

increases expression

Selenium results in increased expression of AK1 mRNA

NCBI chr 9:127,866,480...127,879,621
Ensembl chr 9:127,866,486...127,877,675

G

adenylate kinase 2

increases expression

Selenium results in increased expression of AK2 mRNA

NCBI chr 1:33,007,940...33,036,883
Ensembl chr 1:33,007,986...33,080,996

G

adenylate kinase 3

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of AK3 mRNA

NCBI chr 9:4,709,556...4,742,043
Ensembl chr 9:4,709,556...4,742,043

G

A-kinase anchoring protein 13

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of AKAP13 mRNA

NCBI chr15:85,380,603...85,749,358
Ensembl chr15:85,380,571...85,749,358

G

AKT serine/threonine kinase 1

multiple interactions
increases phosphorylation
increases expression
decreases phosphorylation

[Selenium results in decreased phosphorylation of AKT1 protein] which results in increased susceptibility to Doxorubicin; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]; Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of AKT1 protein]
Selenium results in increased phosphorylation of AKT1 protein
Selenium inhibits the reaction [arsenite results in decreased expression of and results in decreased phosphorylation of AKT1 protein]; Selenium inhibits the reaction [Potassium Iodide results in increased phosphorylation of AKT1 protein]
Selenium inhibits the reaction [Hydrogen Peroxide results in decreased phosphorylation of and results in decreased activity of AKT1 protein]
Selenium results in increased expression of AKT1 mRNA

PMID:17339365 PMID:17997286 PMID:19244175 PMID:29324385 PMID:38013145

NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751

G

aminolevulinate dehydratase

multiple interactions

Selenium inhibits the reaction [Arsenic results in decreased activity of ALAD protein]

NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290

G

5'-aminolevulinate synthase 1

increases expression

Selenium results in increased expression of ALAS1 mRNA

NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327

G

albumin

multiple interactions

Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]

NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482

G

activated leukocyte cell adhesion molecule

decreases expression

Selenium results in decreased expression of ALCAM mRNA

NCBI chr 3:105,366,909...105,576,900
Ensembl chr 3:105,366,909...105,576,900

G

aldehyde dehydrogenase 1 family member B1

increases expression

Selenium deficiency results in increased expression of ALDH1B1 mRNA

NCBI chr 9:38,392,702...38,398,661
Ensembl chr 9:38,392,702...38,398,661

G

aldehyde dehydrogenase 1 family member L1

affects expression

Selenium affects the expression of ALDH1L1 protein

NCBI chr 3:126,103,570...126,197,945
Ensembl chr 3:126,103,562...126,197,994

G

aldehyde dehydrogenase 4 family member A1

increases expression

Selenium results in increased expression of ALDH4A1 mRNA

NCBI chr 1:18,871,430...18,902,555
Ensembl chr 1:18,871,430...18,902,724

G

aldolase, fructose-bisphosphate A

increases expression

Selenium results in increased expression of ALDOA mRNA

NCBI chr16:30,064,279...30,070,420
Ensembl chr16:30,064,164...30,070,457

G

ALG3 alpha-1,3- mannosyltransferase

increases expression

Selenium results in increased expression of ALG3 mRNA

NCBI chr 3:184,242,301...184,249,525
Ensembl chr 3:184,242,301...184,249,548

G

ALG9 alpha-1,2-mannosyltransferase

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ALG9 mRNA

NCBI chr11:111,768,025...111,871,581
Ensembl chr11:111,782,195...111,871,581

G

arachidonate 15-lipoxygenase

increases expression
multiple interactions

Selenium deficiency results in increased expression of ALOX15 mRNA
Selenomethionine inhibits the reaction [Selenium deficiency results in increased expression of ALOX15 protein]; Sodium Selenite inhibits the reaction [Selenium deficiency results in increased expression of ALOX15 protein]

PMID:11444866 PMID:34970773

NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294

G

arachidonate 5-lipoxygenase

multiple interactions

[Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of ALOX5 protein

NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119

G

ALS2 C-terminal like

increases expression

Selenium results in increased expression of ALS2CL mRNA

NCBI chr 3:46,668,995...46,693,679
Ensembl chr 3:46,668,995...46,693,704

G

adenosine monophosphate deaminase 3

decreases expression

Selenium results in decreased expression of AMPD3 mRNA

NCBI chr11:10,450,388...10,507,579
Ensembl chr11:10,308,313...10,507,579

G

amylase alpha 2A

decreases expression

Selenium results in decreased expression of AMY2A mRNA

NCBI chr 1:103,616,651...103,625,780
Ensembl chr 1:103,617,427...103,625,780

G

anaphase promoting complex subunit 15

increases expression

Selenium results in increased expression of ANAPC15 mRNA

NCBI chr11:72,106,372...72,112,780
Ensembl chr11:72,106,378...72,112,780

G

anaphase promoting complex subunit 2

increases expression

Selenium results in increased expression of ANAPC2 mRNA

NCBI chr 9:137,174,784...137,188,560
Ensembl chr 9:137,174,784...137,188,560

G

angiopoietin 1

decreases expression

Selenium results in decreased expression of ANGPT1 mRNA

NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055

G

ankyrin 3

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ANK3 mRNA

NCBI chr10:60,026,298...60,733,528
Ensembl chr10:60,026,298...60,733,490

G

ankyrin repeat family A member 2

decreases expression

Selenium results in decreased expression of ANKRA2 mRNA

NCBI chr 5:73,552,190...73,565,639
Ensembl chr 5:73,552,190...73,565,667

G

acidic nuclear phosphoprotein 32 family member B

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ANP32B mRNA

NCBI chr 9:97,983,341...98,015,943
Ensembl chr 9:97,983,341...98,015,943

G

alanyl aminopeptidase, membrane

increases expression

Selenium results in increased expression of ANPEP mRNA

NCBI chr15:89,784,895...89,814,852
Ensembl chr15:89,784,895...89,815,401

G

aldehyde oxidase 1

multiple interactions
decreases expression

Selenium deficiency results in decreased expression of and results in decreased activity of AOX1 protein
Selenium deficiency results in decreased expression of AOX1 mRNA

NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064

G

aldehyde oxidase 3, pseudogene

increases expression

Selenium deficiency results in increased expression of AOX3 mRNA; Selenium results in increased expression of AOX3 mRNA

NCBI chr 2:200,695,723...200,738,781
Ensembl chr 2:200,678,233...200,732,539

G

adaptor related protein complex 1 subunit beta 1

increases expression

Selenium results in increased expression of AP1B1 mRNA

NCBI chr22:29,327,680...29,388,570
Ensembl chr22:29,327,680...29,388,583

G

adaptor related protein complex 1 subunit mu 2

increases expression

Selenium results in increased expression of AP1M2 mRNA

NCBI chr19:10,572,671...10,587,312
Ensembl chr19:10,572,671...10,587,315

G

adaptor related protein complex 2 subunit alpha 2

increases expression

Selenium results in increased expression of AP2A2 mRNA

NCBI chr11:925,870...1,012,240
Ensembl chr11:924,881...1,012,245

G

adaptor related protein complex 2 subunit mu 1

increases expression

Selenium results in increased expression of AP2M1 mRNA

NCBI chr 3:184,174,855...184,184,091
Ensembl chr 3:184,174,689...184,184,214

G

adaptor related protein complex 2 subunit sigma 1

increases expression

Selenium results in increased expression of AP2S1 mRNA

NCBI chr19:46,838,167...46,850,846
Ensembl chr19:46,838,136...46,850,846

G

APC regulator of WNT signaling pathway

decreases expression

Selenium results in decreased expression of APC mRNA

NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,518...112,846,239

G

acylaminoacyl-peptide hydrolase

increases expression

Selenium results in increased expression of APEH mRNA

NCBI chr 3:49,673,117...49,683,971
Ensembl chr 3:49,674,014...49,683,971

G

amyloid beta precursor like protein 2

increases expression

Selenium results in increased expression of APLP2 mRNA

NCBI chr11:130,069,894...130,144,805
Ensembl chr11:130,068,147...130,144,811

G

apolipoprotein B

multiple interactions
decreases expression

Selenium inhibits the reaction [Cholesterol results in increased expression of APOB protein]
Selenium results in decreased expression of APOB protein

PMID:16271152 PMID:16581047

NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073

G

apolipoprotein E

increases expression
affects expression

Selenium results in increased expression of APOE mRNA
Selenium affects the expression of APOE protein

PMID:17996733 PMID:19244175

NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393

G

apolipoprotein L1

increases expression

Selenium results in increased expression of APOL1 mRNA

NCBI chr22:36,253,133...36,267,525
Ensembl chr22:36,253,071...36,267,530

G

apolipoprotein L3

increases expression

Selenium results in increased expression of APOL3 mRNA

NCBI chr22:36,140,323...36,166,177
Ensembl chr22:36,140,329...36,166,177

G

amyloid beta precursor protein

decreases expression

Selenium results in decreased expression of APP mRNA

NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128

G

amyloid beta precursor protein binding protein 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of APPBP2 mRNA

NCBI chr17:60,443,158...60,526,242
Ensembl chr17:60,443,158...60,526,242

G

aquaporin 3 (Gill blood group)

increases expression
multiple interactions

Selenium results in increased expression of AQP3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of AQP3 mRNA

NCBI chr 9:33,441,160...33,447,593
Ensembl chr 9:33,441,156...33,447,596

G

androgen receptor

multiple interactions
decreases localization
decreases expression

Selenium results in decreased expression of and results in decreased activity of AR protein
Selenium results in decreased localization of AR protein
Selenium results in decreased expression of AR mRNA

PMID:14729601 PMID:16648561

NCBI chr X:67,544,021...67,730,619
Ensembl chr X:67,544,021...67,730,619

G

A-Raf proto-oncogene, serine/threonine kinase

increases expression
multiple interactions

Selenium results in increased expression of ARAF mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ARAF mRNA

NCBI chr X:47,561,205...47,571,908
Ensembl chr X:47,561,205...47,571,908

G

ADP ribosylation factor 5

increases expression

Selenium results in increased expression of ARF5 mRNA

NCBI chr 7:127,588,411...127,591,700
Ensembl chr 7:127,588,386...127,591,700

G

ADP ribosylation factor GTPase activating protein 2

increases expression

Selenium results in increased expression of ARFGAP2 mRNA

NCBI chr11:47,164,301...47,176,879
Ensembl chr11:47,164,299...47,177,125

G

ADP ribosylation factor interacting protein 2

increases expression

Selenium results in increased expression of ARFIP2 mRNA

NCBI chr11:6,476,519...6,481,331
Ensembl chr11:6,474,683...6,481,479

G

ADP ribosylation factor related protein 1

increases expression

Selenium results in increased expression of ARFRP1 mRNA

NCBI chr20:63,698,647...63,707,976
Ensembl chr20:63,698,642...63,708,025

G

arginase 1

multiple interactions

2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; 4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; [Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein; [Selenium co-treated with IL4 protein] results in increased expression of ARG1 mRNA; leflunomide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; rosiglitazone promotes the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]

NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332

G

arginase 2

decreases expression

Selenium results in decreased expression of ARG2 mRNA

NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708

G

Rho GDP dissociation inhibitor alpha

increases expression

Selenium results in increased expression of ARHGDIA mRNA

NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,721...81,871,378

G

ariadne RBR E3 ubiquitin protein ligase 1

decreases expression

Selenium results in decreased expression of ARIH1 mRNA

NCBI chr15:72,474,330...72,602,987
Ensembl chr15:72,474,330...72,602,987

G

ADP ribosylation factor like GTPase 5A

decreases expression

Selenium results in decreased expression of ARL5A mRNA

NCBI chr 2:151,798,797...151,828,421
Ensembl chr 2:151,788,984...151,828,492

G

ADP ribosylation factor like GTPase 6 interacting protein 4

increases expression

Selenium results in increased expression of ARL6IP4 mRNA

NCBI chr12:122,980,233...122,982,909
Ensembl chr12:122,980,060...122,982,913

G

actin related protein 2/3 complex subunit 1A

increases expression

Selenium results in increased expression of ARPC1A mRNA

NCBI chr 7:99,325,898...99,366,262
Ensembl chr 7:99,325,898...99,366,262

G

actin related protein 2/3 complex subunit 1B

increases expression

Selenium results in increased expression of ARPC1B mRNA

NCBI chr 7:99,374,259...99,394,816
Ensembl chr 7:99,374,249...99,394,816

G

actin related protein 2/3 complex subunit 4

increases expression

Selenium results in increased expression of ARPC4 mRNA

NCBI chr 3:9,792,518...9,807,101
Ensembl chr 3:9,792,495...9,807,101

G

arsenite methyltransferase

multiple interactions

Selenium inhibits the reaction [AS3MT protein results in increased methylation of Arsenic]

NCBI chr10:102,869,470...102,901,899
Ensembl chr10:102,869,470...102,901,899

G

ArfGAP with SH3 domain, ankyrin repeat and PH domain 3

increases expression

Selenium results in increased expression of ASAP3 mRNA

NCBI chr 1:23,428,563...23,484,631
Ensembl chr 1:23,428,563...23,484,637

G

ankyrin repeat and SOCS box containing 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ASB1 mRNA
Selenium results in increased expression of ASB1 mRNA

NCBI chr 2:238,426,927...238,452,250
Ensembl chr 2:238,426,742...238,452,250

G

activating signal cointegrator 1 complex subunit 2

increases expression

Selenium results in increased expression of ASCC2 mRNA

NCBI chr22:29,788,611...29,838,274
Ensembl chr22:29,788,609...29,838,304

G

argininosuccinate lyase

increases expression

Selenium results in increased expression of ASL mRNA

NCBI chr 7:66,075,819...66,093,576
Ensembl chr 7:66,075,800...66,094,697

G

acetylserotonin O-methyltransferase like

increases expression

Selenium results in increased expression of ASMTL mRNA

NCBI chr  X:1,403,139...1,453,756
NCBI chr  Y:1,403,139...1,453,756
Ensembl chr  Y:1,403,139...1,453,762
Ensembl chr  X:1,403,139...1,453,762

G

argininosuccinate synthase 1

increases expression

Selenium results in increased expression of ASS1 mRNA

NCBI chr 9:130,444,707...130,501,274
Ensembl chr 9:130,444,961...130,501,274

G

ASXL transcriptional regulator 1

decreases expression

Selenium results in decreased expression of ASXL1 mRNA

NCBI chr20:32,358,331...32,439,319
Ensembl chr20:32,358,330...32,439,319

G

ASXL transcriptional regulator 2

decreases expression

Selenium results in decreased expression of ASXL2 mRNA

NCBI chr 2:25,733,753...25,878,487
Ensembl chr 2:25,733,753...25,878,487

G

activating transcription factor 4

increases expression

Selenium results in increased expression of ATF4 mRNA

NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,683

G

activating transcription factor 5

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATF5 mRNA
Selenium results in increased expression of ATF5 mRNA

NCBI chr19:49,928,906...49,933,935
Ensembl chr19:49,928,702...49,933,935

G

autophagy related 12

decreases expression

Selenium results in decreased expression of ATG12 mRNA

NCBI chr 5:115,828,200...115,841,565
Ensembl chr 5:115,828,200...115,841,837

G

autophagy related 13

increases expression

Selenium results in increased expression of ATG13 mRNA

NCBI chr11:46,617,553...46,674,518
Ensembl chr11:46,617,527...46,674,818

G

autophagy related 14

decreases expression

Selenium results in decreased expression of ATG14 mRNA

NCBI chr14:55,366,391...55,411,830
Ensembl chr14:55,366,391...55,411,830

G

autophagy related 9A

increases expression

Selenium results in increased expression of ATG9A mRNA

NCBI chr 2:219,219,380...219,229,636
Ensembl chr 2:219,219,380...219,229,717

G

ATM interactor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of ATMIN mRNA
Selenium results in decreased expression of ATMIN mRNA

NCBI chr16:81,035,842...81,047,350
Ensembl chr16:81,035,842...81,047,350

G

ATPase phospholipid transporting 10D (putative)

decreases expression

Selenium results in decreased expression of ATP10D mRNA

NCBI chr 4:47,485,275...47,593,486
Ensembl chr 4:47,485,275...47,593,486

G

ATPase plasma membrane Ca2+ transporting 4

increases expression

Selenium results in increased expression of ATP2B4 mRNA

NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081

G

ATPase secretory pathway Ca2+ transporting 1

decreases expression

Selenium results in decreased expression of ATP2C1 mRNA

NCBI chr 3:130,850,595...131,016,712
Ensembl chr 3:130,850,595...131,016,712

G

ATP synthase membrane subunit e

decreases expression

Selenium results in decreased expression of ATP5ME mRNA

NCBI chr 4:672,436...674,276
Ensembl chr 4:672,436...674,330

G

ATP synthase peripheral stalk subunit d

decreases expression

Selenium results in decreased expression of ATP5PD mRNA

NCBI chr17:75,038,863...75,046,969
Ensembl chr17:75,038,863...75,046,985

G

ATP synthase peripheral stalk subunit F6

decreases expression

Selenium results in decreased expression of ATP5PF mRNA

NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673

G

ATPase H+ transporting accessory protein 1

increases expression

Selenium results in increased expression of ATP6AP1 mRNA

NCBI chr X:154,428,677...154,436,516
Ensembl chr X:154,428,633...154,436,516

G

ATPase H+ transporting V0 subunit d1

increases expression

Selenium results in increased expression of ATP6V0D1 mRNA

NCBI chr16:67,438,019...67,481,157
Ensembl chr16:67,438,014...67,481,181

G

ATPase H+ transporting V0 subunit e1

decreases expression

Selenium results in decreased expression of ATP6V0E mRNA

NCBI chr 5:172,983,771...173,035,445
Ensembl chr 5:172,983,771...173,035,445

G

ATPase H+ transporting V1 subunit C1

decreases expression

Selenium results in decreased expression of ATP6V1C1 mRNA

NCBI chr 8:103,021,083...103,073,051
Ensembl chr 8:103,021,063...103,073,051

G

ATRX chromatin remodeler

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ATRX mRNA
Selenium results in decreased expression of ATRX mRNA

NCBI chr X:77,504,880...77,786,216
Ensembl chr X:77,504,880...77,786,233

G

ataxin 1

decreases expression

Selenium results in decreased expression of ATXN1 mRNA

NCBI chr 6:16,299,112...16,761,460
Ensembl chr 6:16,299,112...16,761,491

G

ataxin 7

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ATXN7 mRNA
Selenium results in decreased expression of ATXN7 mRNA

NCBI chr 3:63,863,144...64,003,462
Ensembl chr 3:63,863,155...64,003,462

G

AVL9 cell migration associated

decreases expression

Selenium results in decreased expression of AVL9 mRNA

NCBI chr 7:32,495,489...32,588,726
Ensembl chr 7:32,495,426...32,588,726

G

AXL receptor tyrosine kinase

decreases expression

Selenium results in decreased expression of AXL mRNA

NCBI chr19:41,219,223...41,261,766
Ensembl chr19:41,219,223...41,261,766

G

beta-1,3-glucuronyltransferase 3

increases expression

Selenium results in increased expression of B3GAT3 mRNA

NCBI chr11:62,615,296...62,621,986
Ensembl chr11:62,615,296...62,622,154

G

BAG cochaperone 1

increases expression

Selenium results in increased expression of BAG1 mRNA

NCBI chr 9:33,252,471...33,264,708
Ensembl chr 9:33,247,820...33,264,720

G

BAG cochaperone 6

increases expression

Selenium results in increased expression of BAG6 mRNA

NCBI chr 6:31,639,028...31,652,661
Ensembl chr 6:31,639,028...31,652,705

G

BRCA1 associated protein 1

increases expression

Selenium results in increased expression of BAP1 mRNA

NCBI chr 3:52,401,008...52,410,008
Ensembl chr 3:52,401,008...52,410,008

G

BRCA1 associated RING domain 1

decreases expression

Selenium results in decreased expression of BARD1 mRNA

NCBI chr 2:214,725,646...214,809,683
Ensembl chr 2:214,725,646...214,809,683

G

basic leucine zipper ATF-like transcription factor

increases expression

Selenium results in increased expression of BATF mRNA

NCBI chr14:75,522,469...75,546,992
Ensembl chr14:75,522,455...75,546,993

G

BCL2 associated X, apoptosis regulator

decreases expression
multiple interactions

Selenium results in decreased expression of BAX protein
Selenium inhibits the reaction [arsenite results in increased expression of BAX protein]
[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of BAX mRNA]

PMID:16307838 PMID:17997286 PMID:27920530 PMID:29324385

NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798

G

bromodomain adjacent to zinc finger domain 1B

increases expression

Selenium results in increased expression of BAZ1B mRNA

NCBI chr 7:73,440,406...73,522,293
Ensembl chr 7:73,440,406...73,522,293

G

BBX high mobility group box domain containing

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BBX mRNA
Selenium results in decreased expression of BBX mRNA

NCBI chr 3:107,522,962...107,811,339
Ensembl chr 3:107,522,936...107,811,339

G

BCL11 transcription factor A

decreases expression

Selenium results in decreased expression of BCL11A mRNA

NCBI chr 2:60,450,520...60,553,924
Ensembl chr 2:60,450,520...60,554,467

G

BCL2 apoptosis regulator

decreases expression
multiple interactions

Selenium results in decreased expression of BCL2 protein
Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of BCL2 mRNA]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of BCL2 protein]

PMID:17523932 PMID:27920530 PMID:34612572

NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128

G

BCL2 like 1

increases expression
multiple interactions

Selenium results in increased expression of BCL2L1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BCL2L1 mRNA

PMID:11444866 PMID:19244175

NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989

G

BCL2 like 11

multiple interactions
increases expression

BCL2L11 protein affects the susceptibility to [Doxorubicin co-treated with Selenium]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]
Selenium results in increased expression of BCL2L11 protein

NCBI chr 2:111,120,914...111,168,445
Ensembl chr 2:111,119,378...111,168,444

G

BCL3 transcription coactivator

increases expression

Selenium results in increased expression of BCL3 mRNA

NCBI chr19:44,747,705...44,760,044
Ensembl chr19:44,747,705...44,760,044

G

BAF chromatin remodeling complex subunit BCL7B

increases expression

Selenium results in increased expression of BCL7B mRNA

NCBI chr 7:73,536,356...73,557,690
Ensembl chr 7:73,536,356...73,557,690

G

BCL2 associated transcription factor 1

decreases expression
multiple interactions

Selenium results in decreased expression of BCLAF1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of BCLAF1 mRNA

NCBI chr 6:136,256,627...136,289,846
Ensembl chr 6:136,256,627...136,289,851

G

3-hydroxybutyrate dehydrogenase 2

decreases expression

Selenium results in decreased expression of BDH2 mRNA

NCBI chr 4:103,077,592...103,099,834
Ensembl chr 4:103,077,592...103,099,870

G

brain derived neurotrophic factor

increases expression
multiple interactions

Selenium results in increased expression of BDNF protein
Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in decreased expression of BDNF protein]

NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058

G

beclin 1

multiple interactions

Selenium deficiency inhibits the reaction [T-2 Toxin results in increased expression of BECN1 mRNA]

NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350

G

BICD cargo adaptor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BICD1 mRNA
Selenium results in decreased expression of BICD1 mRNA

NCBI chr12:32,106,847...32,383,633
Ensembl chr12:32,106,835...32,383,633

G

BICD family like cargo adaptor 1

increases expression

Selenium results in increased expression of BICDL1 mRNA

NCBI chr12:119,989,236...120,094,495
Ensembl chr12:119,989,236...120,094,494

G

BRD4 interacting chromatin remodeling complex associated protein

increases expression

Selenium results in increased expression of BICRA mRNA

NCBI chr19:47,608,196...47,703,277
Ensembl chr19:47,608,196...47,703,277

G

BH3 interacting domain death agonist

increases cleavage

Selenium results in increased cleavage of BID protein

NCBI chr22:17,734,138...17,774,665
Ensembl chr22:17,734,138...17,774,770

G

bridging integrator 1

increases expression

Selenium results in increased expression of BIN1 mRNA

NCBI chr 2:127,048,023...127,107,154
Ensembl chr 2:127,048,027...127,107,288

G

baculoviral IAP repeat containing 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of BIRC2 mRNA

NCBI chr11:102,347,214...102,378,670
Ensembl chr11:102,347,211...102,378,670

G

baculoviral IAP repeat containing 5

affects response to substance
multiple interactions

BIRC5 protein affects the susceptibility to Selenium
[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of BIRC5 mRNA]

PMID:17876054 PMID:27920530

NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636

G

bridge-like lipid transfer protein family member 2

increases expression

Selenium results in increased expression of BLTP2 mRNA

NCBI chr17:28,614,440...28,645,159
Ensembl chr17:28,614,446...28,645,454

G

bridge-like lipid transfer protein family member 3B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BLTP3B mRNA
Selenium results in decreased expression of BLTP3B mRNA

NCBI chr12:100,037,072...100,142,874
Ensembl chr12:100,028,455...100,142,874

G

biliverdin reductase B

increases expression

Selenium results in increased expression of BLVRB mRNA

NCBI chr19:40,447,768...40,465,745
Ensembl chr19:40,447,765...40,465,764

G

bromodomain PHD finger transcription factor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BPTF mRNA
Selenium results in decreased expression of BPTF mRNA

NCBI chr17:67,825,503...67,984,378
Ensembl chr17:67,825,503...67,984,378

G

bromodomain containing 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of BRD2 mRNA
Selenium results in increased expression of BRD2 mRNA

NCBI chr 6:32,968,594...32,981,505
Ensembl chr 6:32,968,594...32,981,505

G

BRF2 RNA polymerase III transcription initiation factor subunit

increases expression

Selenium results in increased expression of BRF2 mRNA

NCBI chr 8:37,843,268...37,849,861
Ensembl chr 8:37,843,268...37,849,861

G

BRMS1 transcriptional repressor and anoikis regulator

increases expression

Selenium results in increased expression of BRMS1 mRNA

NCBI chr11:66,337,339...66,345,104
Ensembl chr11:66,337,333...66,345,125

G

BSCL2 lipid droplet biogenesis associated, seipin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of BSCL2 mRNA
Selenium results in increased expression of BSCL2 mRNA

NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845

G

bone marrow stromal cell antigen 2

increases expression

Selenium results in increased expression of BST2 mRNA

NCBI chr19:17,402,939...17,405,630
Ensembl chr19:17,402,939...17,405,630

G

bystin like

increases expression

Selenium results in increased expression of BYSL mRNA

NCBI chr 6:41,908,759...41,933,046
Ensembl chr 6:41,921,499...41,933,046

G

chromosome 11 open reading frame 68

increases expression

Selenium results in increased expression of C11ORF68 mRNA

NCBI chr11:65,916,810...65,919,062
Ensembl chr11:65,916,810...65,919,062

G

chromosome 14 open reading frame 132

decreases expression

Selenium results in decreased expression of C14ORF132 mRNA

NCBI chr14:96,039,362...96,093,971
Ensembl chr14:96,039,362...96,093,971

G

chromosome 1 open reading frame 50

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of C1ORF50 mRNA
Selenium results in decreased expression of C1ORF50 mRNA

NCBI chr 1:42,767,249...42,779,491
Ensembl chr 1:42,767,245...42,779,491

G

chromosome 1 open reading frame 54

decreases expression

Selenium results in decreased expression of C1ORF54 mRNA

NCBI chr 1:150,268,731...150,280,924
Ensembl chr 1:150,268,200...150,280,916

G

complement C1q B chain

increases expression

Selenium results in increased expression of C1QB mRNA

NCBI chr 1:22,653,236...22,661,637
Ensembl chr 1:22,652,762...22,661,637

G

C2 calcium dependent domain containing 5

decreases expression

Selenium results in decreased expression of C2CD5 mRNA

NCBI chr12:22,448,583...22,544,542
Ensembl chr12:22,448,583...22,544,546

G

chromosome 2 open reading frame 42

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of C2ORF42 mRNA
Selenium results in decreased expression of C2ORF42 mRNA

NCBI chr 2:70,149,885...70,191,019
Ensembl chr 2:70,149,885...70,248,615

G

chromosome 7 open reading frame 25

decreases expression

Selenium results in decreased expression of C7ORF25 mRNA

NCBI chr 7:42,909,273...42,912,070
Ensembl chr 7:42,909,273...42,912,305

G

carbonic anhydrase 3

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CA3 mRNA

NCBI chr 8:85,438,859...85,449,040
Ensembl chr 8:85,373,436...85,449,040

G

calcineurin binding protein 1

increases expression

Selenium results in increased expression of CABIN1 mRNA

NCBI chr22:24,011,304...24,178,628
Ensembl chr22:24,011,192...24,178,628

G

calcium binding and coiled-coil domain 1

increases expression

Selenium results in increased expression of CALCOCO1 mRNA

NCBI chr12:53,708,517...53,727,452
Ensembl chr12:53,708,517...53,727,745

G

caldesmon 1

decreases expression

Selenium results in decreased expression of CALD1 mRNA

NCBI chr 7:134,745,467...134,970,729
Ensembl chr 7:134,744,252...134,970,729

G

calcium homeostasis modulator family member 2

increases expression

Selenium results in increased expression of CALHM2 mRNA

NCBI chr10:103,446,786...103,452,370
Ensembl chr10:103,446,786...103,452,402

G

calmodulin 3

increases expression

Selenium results in increased expression of CALM3 mRNA

NCBI chr19:46,601,074...46,610,782
Ensembl chr19:46,601,074...46,610,782

G

calreticulin

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CALR mRNA
Selenium results in decreased expression of CALR mRNA

NCBI chr19:12,938,609...12,944,489
Ensembl chr19:12,938,578...12,944,489

G

calumenin

increases expression
multiple interactions

Selenium results in increased expression of CALU mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CALU mRNA

NCBI chr 7:128,739,359...128,773,400
Ensembl chr 7:128,739,292...128,773,400

G

calcium/calmodulin dependent protein kinase II beta

increases expression

Selenium results in increased expression of CAMK2B mRNA

NCBI chr 7:44,217,154...44,326,013
Ensembl chr 7:44,210,019...44,334,577

G

cyclase associated actin cytoskeleton regulatory protein 2

decreases expression

Selenium results in decreased expression of CAP2 mRNA

NCBI chr 6:17,393,595...17,557,780
Ensembl chr 6:17,393,595...17,557,780

G

capping actin protein, gelsolin like

increases expression

Selenium results in increased expression of CAPG mRNA

NCBI chr 2:85,391,602...85,419,540
Ensembl chr 2:85,394,753...85,418,432

G

calpain 1

increases expression

Selenium results in increased expression of CAPN1 mRNA

NCBI chr11:65,181,373...65,212,006
Ensembl chr11:65,180,566...65,212,006

G

calpain 7

decreases expression

Selenium results in decreased expression of CAPN7 mRNA

NCBI chr 3:15,206,246...15,252,916
Ensembl chr 3:15,206,152...15,252,916

G

calpain small subunit 1

increases expression

Selenium results in increased expression of CAPNS1 mRNA

NCBI chr19:36,140,066...36,150,353
Ensembl chr19:36,139,953...36,150,353

G

capping actin protein of muscle Z-line subunit beta

increases expression

Selenium results in increased expression of CAPZB mRNA

NCBI chr 1:19,338,775...19,485,539
Ensembl chr 1:19,338,775...19,485,539

G

CASC3 exon junction complex subunit

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of MLN51 mRNA

NCBI chr17:40,140,537...40,172,171
Ensembl chr17:40,140,318...40,172,171

G

caspase 12 (gene/pseudogene)

multiple interactions

Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]

NCBI chr11:104,883,286...104,898,460
Ensembl chr11:104,885,718...104,898,670

G

caspase 3

decreases activity
multiple interactions
increases activity

Selenium results in decreased activity of CASP3 protein
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CASP3 mRNA]; Selenium inhibits the reaction [nickel sulfate results in decreased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP3 mRNA]; Selenium deficiency promotes the reaction [T-2 Toxin results in increased expression of CASP3 protein modified form]; Selenium inhibits the reaction [arsenite results in increased expression of CASP3 protein]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein modified form]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]
Selenium results in increased activity of CASP3 protein

PMID:15318939 PMID:17997286 PMID:21628957 PMID:27920530 PMID:29324385 More...

NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062

G

caspase 8

multiple interactions
increases activity
decreases expression

[Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein]; [Doxorubicin co-treated with Selenium] promotes the reaction [FAS protein binds to CASP8 protein]; Selenium analog inhibits the reaction [Diazinon results in increased expression of CASP8 mRNA]
Selenium results in increased activity of CASP8 protein
Selenium results in decreased expression of CASP8 mRNA

PMID:12432279 PMID:17970047 PMID:19244175 PMID:27920530

NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836

G

caspase 9

multiple interactions
decreases activity

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]]; [Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased cleavage of and results in increased activity of CASP9 protein]; Selenium analog inhibits the reaction [Magnesium Oxide analog inhibits the reaction [Diazinon results in increased expression of CASP9 mRNA]]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [arsenite results in increased expression of CASP9 mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]
Selenium results in decreased activity of CASP9 protein

PMID:17339365 PMID:17997286 PMID:21628957 PMID:27920530 PMID:29324385 More...

NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534

G

catalase

multiple interactions
increases activity
decreases expression
increases expression

Arsenic promotes the reaction [Selenium results in increased expression of CAT protein]; Fluorides promotes the reaction [Selenium results in increased activity of CAT protein]; Selenium inhibits the reaction [Fluorides results in decreased activity of CAT protein]
Selenium deficiency results in decreased expression of CAT mRNA
[[Sodium Selenite results in increased abundance of Selenium] which co-treated with Ascorbic Acid] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased activity of CAT protein; [Selenium co-treated with Vitamin E] inhibits the reaction [Malathion results in decreased activity of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [barium chloride results in decreased activity of CAT protein]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in decreased activity of CAT protein]; Selenium affects the reaction [Clofibrate results in increased activity of CAT protein]; Selenium affects the reaction [Mercury results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in decreased activity of CAT protein]; Selenium inhibits the reaction [chromium hexavalent ion results in increased activity of CAT protein]; Selenium inhibits the reaction [Chromium results in increased activity of CAT protein]; Selenium inhibits the reaction [cyfluthrin results in decreased activity of CAT protein]; Selenium inhibits the reaction [Enrofloxacin results in decreased activity of CAT protein]; Selenium inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Selenium inhibits the reaction [nickel sulfate results in increased activity of CAT protein]; Selenium inhibits the reaction [Potassium Dichromate results in decreased activity of CAT protein]; Selenium inhibits the reaction [Potassium Dichromate results in increased activity of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]]

PMID:3456598 PMID:8250967 PMID:11260395 PMID:17512462 PMID:19652462 More...

NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060

G

caveolae associated protein 1

increases expression

Selenium results in increased expression of CAVIN1 mRNA

NCBI chr17:42,402,449...42,423,256
Ensembl chr17:42,402,449...42,423,256

G

Cbl proto-oncogene B

decreases expression

Selenium results in decreased expression of CBLB mRNA

NCBI chr 3:105,655,461...105,869,449
Ensembl chr 3:105,655,461...105,869,552

G

chromobox 5

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CBX5 mRNA
Selenium results in decreased expression of CBX5 mRNA

NCBI chr12:54,230,942...54,280,122
Ensembl chr12:54,230,942...54,280,133

G

chromobox 7

increases expression

Selenium results in increased expression of CBX7 mRNA

NCBI chr22:39,130,772...39,152,680
Ensembl chr22:39,120,167...39,152,680

G

coiled-coil domain containing 85B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DIPA mRNA
Selenium results in increased expression of DIPA mRNA

NCBI chr11:65,890,673...65,891,635
Ensembl chr11:65,890,673...65,891,635

G

coiled-coil alpha-helical rod protein 1

increases expression

Selenium results in increased expression of CCHCR1 mRNA

NCBI chr 6:31,142,439...31,158,197
Ensembl chr 6:31,142,439...31,158,238

G

C-C motif chemokine ligand 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of CCL2 mRNA; Selenium inhibits the reaction [Glucose results in increased expression of CCL2 mRNA]; Selenium inhibits the reaction [Hydrogen Peroxide results in increased expression of CCL2 mRNA]

PMID:16143069 PMID:21481475

NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208

G

C-C motif chemokine ligand 3 like 1

increases expression

Selenium results in increased expression of CCL3L1 mRNA

Ensembl chr17:36,194,869...36,196,758

G

cyclin B1

decreases expression

Selenium deficiency results in decreased expression of CCNB1 mRNA

NCBI chr 5:69,167,150...69,178,245
Ensembl chr 5:69,167,135...69,178,245

G

cyclin C

decreases expression

Selenium deficiency results in decreased expression of CCNC mRNA

NCBI chr 6:99,542,387...99,568,814
Ensembl chr 6:99,542,387...99,568,825

G

cyclin D1

increases expression
multiple interactions

Selenium results in increased expression of CCND1 mRNA
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of CCND1 mRNA

PMID:11444866 PMID:19244175

NCBI chr11:69,641,156...69,654,474
Ensembl chr11:69,641,156...69,654,474

G

cyclin D2

decreases expression

Selenium deficiency results in decreased expression of CCND2 mRNA

NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353

G

cell cycle progression 1

decreases expression

Selenium results in decreased expression of CPR8 mRNA

NCBI chr15:55,355,239...55,408,359
Ensembl chr15:55,340,032...55,408,510

G

C-C motif chemokine receptor 3

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CCR3 mRNA

NCBI chr 3:46,210,696...46,266,706
Ensembl chr 3:46,130,890...46,266,706

G

coiled-coil serine rich protein 2

decreases expression

Selenium results in decreased expression of CCSER2 mRNA

NCBI chr10:84,328,589...84,518,517
Ensembl chr10:84,328,586...84,518,521

G

CD14 molecule

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of CD14 mRNA

NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700

G

CD2 cytoplasmic tail binding protein 2

increases expression

Selenium results in increased expression of CD2BP2 mRNA

NCBI chr16:30,350,773...30,355,308
Ensembl chr16:30,350,773...30,355,308

G

CD44 molecule (IN blood group)

multiple interactions
increases expression

Selenium inhibits the reaction [T-2 Toxin results in decreased expression of CD44 protein]
Selenium results in increased expression of CD44 mRNA; Selenium results in increased expression of CD44 protein

NCBI chr11:35,139,171...35,232,402
Ensembl chr11:35,138,882...35,232,402

G

CD74 molecule

increases expression

Selenium results in increased expression of CD74 mRNA

NCBI chr 5:150,401,639...150,412,910
Ensembl chr 5:150,401,637...150,412,969

G

CD99 molecule (Xg blood group)

increases expression

Selenium results in increased expression of CD99 mRNA

NCBI chr  X:2,691,295...2,741,309
NCBI chr  Y:2,691,295...2,741,309
Ensembl chr  Y:2,691,187...2,741,309
Ensembl chr  X:2,691,187...2,741,309

G

cell division cycle 14B

decreases expression

Selenium results in decreased expression of CDC14B mRNA

NCBI chr 9:96,490,939...96,619,843
Ensembl chr 9:96,490,241...96,619,843

G

cell division cycle 16

decreases expression

Selenium results in decreased expression of CDC16 mRNA

NCBI chr13:114,234,897...114,272,723
Ensembl chr13:114,234,887...114,272,723

G

cell division cycle 23

decreases expression

Selenium results in decreased expression of CDC23 mRNA

NCBI chr 5:138,187,650...138,213,323
Ensembl chr 5:138,187,650...138,213,343

G

CDC42 binding protein kinase alpha

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CDC42BPA mRNA
Selenium results in decreased expression of CDC42BPA mRNA

NCBI chr 1:226,989,858...227,318,492
Ensembl chr 1:226,989,865...227,318,492

G

CDC42 effector protein 4

increases expression

Selenium results in increased expression of CDC42EP4 mRNA

NCBI chr17:73,283,624...73,312,001
Ensembl chr17:73,283,624...73,312,005

G

cell division cycle 73

decreases expression

Selenium results in decreased expression of CDC73 mRNA

NCBI chr 1:193,122,031...193,254,815
Ensembl chr 1:193,121,983...193,254,815

G

cadherin 11

decreases expression

Selenium results in decreased expression of CDH11 mRNA

NCBI chr16:64,943,753...65,123,744
Ensembl chr16:64,943,753...65,126,112

G

cadherin 3

increases expression

Selenium results in increased expression of CDH3 mRNA

NCBI chr16:68,645,310...68,733,771
Ensembl chr16:68,636,189...68,727,468

G

cyclin dependent kinase 1

decreases expression

Selenium deficiency results in decreased expression of CDK1 mRNA

NCBI chr10:60,778,331...60,794,852
Ensembl chr10:60,778,331...60,794,852

G

cyclin dependent kinase 10

increases expression
multiple interactions

Selenium results in increased expression of CDK10 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CDK10 mRNA

NCBI chr16:89,686,689...89,696,354
Ensembl chr16:89,680,737...89,696,354

G

cyclin dependent kinase 2

decreases expression

Selenium deficiency results in decreased expression of CDK2 mRNA

NCBI chr12:55,966,830...55,972,789
Ensembl chr12:55,966,781...55,972,789

G

cyclin dependent kinase 2 associated protein 2

increases expression

Selenium results in increased expression of CDK2AP2 mRNA

NCBI chr11:67,506,497...67,508,162
Ensembl chr11:67,506,497...67,508,649

G

cyclin dependent kinase 4

decreases expression
increases expression

Selenium deficiency results in decreased expression of CDK4 mRNA
Selenium results in increased expression of CDK4 mRNA

PMID:11925459 PMID:19244175

NCBI chr12:57,747,727...57,752,310
Ensembl chr12:57,747,727...57,756,013

G

cyclin dependent kinase inhibitor 1C

decreases expression

Selenium results in decreased expression of CDKN1C mRNA

NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775

G

CDP-diacylglycerol synthase 1

decreases expression

Selenium results in decreased expression of CDS1 mRNA

NCBI chr 4:84,583,127...84,651,334
Ensembl chr 4:84,583,127...84,651,334

G

CCAAT enhancer binding protein alpha

increases expression

Selenium results in increased expression of CEBPA mRNA

NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534

G

carboxyl ester lipase

increases expression

Selenium results in increased expression of CEL mRNA

NCBI chr 9:133,061,981...133,071,861
Ensembl chr 9:133,061,981...133,071,861

G

CUGBP Elav-like family member 2

decreases expression

Selenium results in decreased expression of CELF2 mRNA

NCBI chr10:10,462,550...11,336,675
Ensembl chr10:10,798,397...11,336,675

G

centrosomal protein 170

decreases expression

Selenium results in decreased expression of CEP170 mRNA

NCBI chr 1:243,124,428...243,255,785
Ensembl chr 1:243,124,428...243,255,348

G

centrosomal protein 290

decreases expression

Selenium results in decreased expression of CEP290 mRNA

NCBI chr12:88,049,016...88,142,088
Ensembl chr12:88,049,016...88,142,099

G

centrosomal protein 350

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CEP350 mRNA
Selenium results in decreased expression of CEP350 mRNA

NCBI chr 1:179,954,810...180,114,875
Ensembl chr 1:179,954,674...180,114,880

G

centrosomal protein 57

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CEP57 mRNA
Selenium results in decreased expression of CEP57 mRNA

NCBI chr11:95,790,498...95,832,693
Ensembl chr11:95,789,965...95,832,693

G

ceramide transporter 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CERT1 mRNA
Selenium results in decreased expression of CERT1 mRNA

NCBI chr 5:75,368,486...75,511,981
Ensembl chr 5:75,356,345...75,512,138

G

carboxylesterase 1

increases expression

Selenium results in increased expression of CES1 mRNA

NCBI chr16:55,802,851...55,833,096
Ensembl chr16:55,802,851...55,833,337

G

complement factor H

decreases expression

Selenium results in decreased expression of CFH mRNA

NCBI chr 1:196,652,043...196,747,504
Ensembl chr 1:196,651,754...196,752,476

G

CASP8 and FADD like apoptosis regulator

multiple interactions

[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CFLAR mRNA]; Selenium analog promotes the reaction [Diazinon results in increased expression of CFLAR mRNA]

NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687

G

chromodomain helicase DNA binding protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of CHD1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of CHD1 mRNA

NCBI chr 5:98,853,985...98,929,007
Ensembl chr 5:98,853,985...98,929,007

G

chromodomain helicase DNA binding protein 3

increases expression

Selenium results in increased expression of CHD3 mRNA

NCBI chr17:7,884,796...7,912,755
Ensembl chr17:7,884,796...7,912,760

G

chromodomain helicase DNA binding protein 4

increases expression

Selenium results in increased expression of CHD4 mRNA

NCBI chr12:6,570,082...6,607,379
Ensembl chr12:6,570,082...6,614,524

G

chromodomain helicase DNA binding protein 9

decreases expression

Selenium results in decreased expression of CHD9 mRNA

NCBI chr16:53,054,991...53,327,497
Ensembl chr16:53,054,991...53,329,150

G

choline kinase alpha

increases expression

Selenium results in increased expression of CHKA mRNA

NCBI chr11:68,052,859...68,121,388
Ensembl chr11:68,052,859...68,121,444

G

charged multivesicular body protein 1A

increases expression

Selenium results in increased expression of CHMP1A mRNA

NCBI chr16:89,644,435...89,657,708
Ensembl chr16:89,640,816...89,657,738

G

charged multivesicular body protein 2A

increases expression

Selenium results in increased expression of CHMP2A mRNA

NCBI chr19:58,551,566...58,555,105
Ensembl chr19:58,551,452...58,555,105

G

chimerin 2

increases expression

Selenium results in increased expression of CHN2 mRNA

NCBI chr 7:29,146,591...29,514,328
Ensembl chr 7:29,146,547...29,514,328

G

cysteine and histidine rich domain containing 1

decreases expression

Selenium results in decreased expression of CHORDC1 mRNA

NCBI chr11:90,200,429...90,223,049
Ensembl chr11:90,200,429...90,223,077

G

chondroitin polymerizing factor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CHPF mRNA
Selenium results in increased expression of CHPF mRNA

NCBI chr 2:219,538,954...219,543,809
Ensembl chr 2:219,538,954...219,543,809

G

cholinergic receptor nicotinic alpha 4 subunit

increases expression

Selenium results in increased expression of CHRNA4 mRNA

NCBI chr20:63,343,223...63,361,349
Ensembl chr20:63,343,223...63,378,401

G

cholinergic receptor nicotinic epsilon subunit

increases expression

Selenium results in increased expression of CHRNE mRNA

NCBI chr17:4,897,771...4,908,677
Ensembl chr17:4,897,771...4,934,438

G

carbohydrate sulfotransferase 3

increases expression

Selenium results in increased expression of CHST3 mRNA

NCBI chr10:71,964,395...72,013,558
Ensembl chr10:71,964,395...72,013,558

G

carbohydrate sulfotransferase 6

increases expression

Selenium results in increased expression of CHST6 mRNA

NCBI chr16:75,472,042...75,495,441
Ensembl chr16:75,472,052...75,495,445

G

CDKN1A interacting zinc finger protein 1

increases expression

Selenium results in increased expression of CIZ1 mRNA

NCBI chr 9:128,166,065...128,204,222
Ensembl chr 9:128,161,251...128,204,383

G

cytoskeleton associated protein 2

decreases expression

Selenium results in decreased expression of CKAP2 mRNA

NCBI chr13:52,455,478...52,476,627
Ensembl chr13:52,455,429...52,476,628

G

creatine kinase B

increases expression

Selenium results in increased expression of CKB mRNA

NCBI chr14:103,519,667...103,522,830
Ensembl chr14:103,519,667...103,522,833

G

CDC28 protein kinase regulatory subunit 2

decreases expression

Selenium results in decreased expression of CKS2 mRNA

NCBI chr 9:89,311,195...89,316,703
Ensembl chr 9:89,311,195...89,316,703

G

chloride channel CLIC like 1

decreases expression

Selenium results in decreased expression of CLCC1 mRNA

NCBI chr 1:108,929,505...108,963,484
Ensembl chr 1:108,881,885...108,963,527

G

chloride voltage-gated channel 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLCN3 mRNA
Selenium results in decreased expression of CLCN3 mRNA

NCBI chr 4:169,620,578...169,723,673
Ensembl chr 4:169,612,633...169,723,673

G

claudin 4

increases expression

Selenium results in increased expression of CLDN4 mRNA

NCBI chr 7:73,830,996...73,832,690
Ensembl chr 7:73,799,542...73,832,690

G

claudin 5

multiple interactions

[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of CLDN5 protein; [Selenium co-treated with Iodine] results in increased expression of and results in increased localization of CLDN5 protein; Selenium results in increased expression of and results in increased localization of CLDN5 protein

NCBI chr22:19,523,024...19,525,337
Ensembl chr22:19,523,024...19,527,545

G

C-type lectin domain family 3 member B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TNA mRNA
Selenium results in increased expression of TNA mRNA

NCBI chr 3:45,026,303...45,036,071
Ensembl chr 3:45,001,548...45,036,071

G

CLN3 lysosomal/endosomal transmembrane protein, battenin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of CLN3 mRNA
Selenium results in increased expression of CLN3 mRNA

NCBI chr16:28,466,653...28,492,082
Ensembl chr16:28,474,111...28,495,575

G

CLPTM1 regulator of GABA type A receptor forward trafficking

increases expression

Selenium results in increased expression of CLPTM1 mRNA

NCBI chr19:44,954,585...44,993,341
Ensembl chr19:44,954,585...44,993,341

G

clathrin light chain B

increases expression

Selenium results in increased expression of CLTB mRNA

NCBI chr 5:176,392,455...176,416,569
Ensembl chr 5:176,392,501...176,416,539

G

clusterin

increases expression

Selenium results in increased expression of CLU mRNA

NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700

G

C-X9-C motif containing 2

decreases expression

Selenium results in decreased expression of CMC2 mRNA

NCBI chr16:80,966,448...81,006,885
Ensembl chr16:80,966,448...81,020,270

G

cornichon family member 1

decreases expression

Selenium results in decreased expression of CNIH1 mRNA

NCBI chr14:54,423,561...54,441,374
Ensembl chr14:54,423,561...54,441,391

G

cornichon family member 4

decreases expression

Selenium results in decreased expression of CNIH4 mRNA

NCBI chr 1:224,356,803...224,379,452
Ensembl chr 1:224,356,858...224,379,459

G

calponin 2

increases expression

Selenium results in increased expression of CNN2 mRNA

NCBI chr19:1,026,608...1,039,065
Ensembl chr19:1,026,586...1,039,068

G

calponin 3

increases expression

Selenium results in increased expression of CNN3 mRNA

NCBI chr 1:94,896,957...94,927,110
Ensembl chr 1:94,896,949...94,927,223

G

CCR4-NOT transcription complex subunit 8

decreases expression

Selenium results in decreased expression of CNOT8 mRNA

NCBI chr 5:154,858,249...154,876,792
Ensembl chr 5:154,857,553...154,876,792

G

canopy FGF signaling regulator 2

decreases expression

Selenium results in decreased expression of CNPY2 mRNA

NCBI chr12:56,309,844...56,316,346
Ensembl chr12:56,309,842...56,316,119

G

canopy FGF signaling regulator 3

increases expression

Selenium results in increased expression of CNPY3 mRNA

NCBI chr 6:42,928,002...42,939,294
Ensembl chr 6:42,929,480...42,939,294

G

component of oligomeric golgi complex 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of COG4 mRNA

NCBI chr16:70,480,567...70,523,554
Ensembl chr16:70,480,568...70,523,560

G

component of oligomeric golgi complex 7

increases expression

Selenium results in increased expression of COG7 mRNA

NCBI chr16:23,388,493...23,453,189
Ensembl chr16:23,388,493...23,453,189

G

component of oligomeric golgi complex 8

increases expression

Selenium results in increased expression of COG8 mRNA

NCBI chr16:69,326,428...69,339,564
Ensembl chr16:69,320,140...69,339,583

G

collagen type XIV alpha 1 chain

decreases expression

Selenium results in decreased expression of COL14A1 mRNA

NCBI chr 8:120,124,454...120,373,573
Ensembl chr 8:120,059,780...120,373,573

G

collagen type XVIII alpha 1 chain

increases expression

Selenium results in increased expression of COL18A1 mRNA

NCBI chr21:45,405,165...45,513,720
Ensembl chr21:45,405,165...45,513,720

G

collagen type I alpha 1 chain

multiple interactions

[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL1A1 protein

NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632

G

collagen type II alpha 1 chain

multiple interactions

[fulvic acid co-treated with Selenium deficiency] affects the metabolism of COL2A1 protein

NCBI chr12:47,972,967...48,006,212
Ensembl chr12:47,972,967...48,004,554

G

collagen type IV alpha 3 chain

decreases expression

Selenium results in decreased expression of COL4A3 mRNA

NCBI chr 2:227,164,624...227,314,792
Ensembl chr 2:227,164,624...227,314,792

G

collagen type VI alpha 2 chain

increases expression

Selenium results in increased expression of COL6A2 mRNA

NCBI chr21:46,098,112...46,132,848
Ensembl chr21:46,098,112...46,132,848

G

collectin subfamily member 12

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of COLEC12 mRNA

NCBI chr18:316,737...500,701
Ensembl chr18:316,737...500,722

G

COMM domain containing 3

decreases expression

Selenium results in decreased expression of COMMD3 mRNA

NCBI chr10:22,316,388...22,320,306
Ensembl chr10:22,316,386...22,320,306

G

COMM domain containing 4

increases expression

Selenium results in increased expression of COMMD4 mRNA

NCBI chr15:75,336,063...75,343,227
Ensembl chr15:75,336,020...75,343,224

G

COPI coat complex subunit epsilon

increases expression

Selenium results in increased expression of COPE mRNA

NCBI chr19:18,899,514...18,919,387
Ensembl chr19:18,899,514...18,919,387

G

COPI coat complex subunit gamma 1

increases expression

Selenium results in increased expression of COPG1 mRNA

NCBI chr 3:129,249,606...129,277,773
Ensembl chr 3:129,249,606...129,277,773

G

COP9 signalosome subunit 7A

increases expression

Selenium results in increased expression of COPS7A mRNA

NCBI chr12:6,724,046...6,731,865
Ensembl chr12:6,724,014...6,731,875

G

COP9 signalosome subunit 8

decreases expression

Selenium results in decreased expression of COPS8 mRNA

NCBI chr 2:237,085,889...237,100,474
Ensembl chr 2:237,085,882...237,100,474

G

cytochrome c oxidase subunit 6A1

decreases expression

Selenium results in decreased expression of COX6A1 mRNA

NCBI chr12:120,438,113...120,440,730
Ensembl chr12:120,438,090...120,440,737

G

cytochrome c oxidase subunit 7A1

decreases expression

Selenium results in decreased expression of COX7A1 mRNA

NCBI chr19:36,150,922...36,152,447
Ensembl chr19:36,150,922...36,152,449

G

cytochrome c oxidase subunit 7A2

decreases expression

Selenium results in decreased expression of COX7A2 mRNA

NCBI chr 6:75,237,675...75,250,298
Ensembl chr 6:75,237,675...75,250,323

G

cytochrome c oxidase subunit 7B

decreases expression

Selenium results in decreased expression of COX7B mRNA

NCBI chr X:77,899,468...77,907,376
Ensembl chr X:77,899,440...77,907,376

G

cytochrome c oxidase subunit 7C

decreases expression

Selenium results in decreased expression of COX7C mRNA

NCBI chr 5:86,617,941...86,620,962
Ensembl chr 5:86,617,928...86,620,962

G

carboxypeptidase A3

decreases expression

Selenium results in decreased expression of CPA3 mRNA

NCBI chr 3:148,865,296...148,897,203
Ensembl chr 3:148,865,296...148,897,203

G

carboxypeptidase D

decreases expression

Selenium results in decreased expression of CPD mRNA

NCBI chr17:30,378,927...30,469,989
Ensembl chr17:30,378,927...30,469,989

G

cleavage and polyadenylation specific factor 1

increases expression

Selenium results in increased expression of CPSF1 mRNA

NCBI chr 8:144,393,231...144,409,335
Ensembl chr 8:144,393,229...144,409,335

G

cellular retinoic acid binding protein 2

increases expression

Selenium deficiency results in increased expression of CRABP2 mRNA

NCBI chr 1:156,699,606...156,705,784
Ensembl chr 1:156,699,606...156,705,816

G

carnitine O-acetyltransferase

increases expression

Selenium results in increased expression of CRAT mRNA

NCBI chr 9:129,094,794...129,110,793
Ensembl chr 9:129,094,142...129,111,189

G

cereblon

decreases expression

Selenium results in decreased expression of CRBN mRNA

NCBI chr 3:3,149,633...3,179,717
Ensembl chr 3:3,144,628...3,179,727

G

cAMP responsive element binding protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CREB1 mRNA
Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in decreased expression of CREB1 protein]
Selenium results in decreased expression of CREB1 mRNA

PMID:19244175 PMID:30695686

NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988

G

cAMP responsive element binding protein 3

increases expression

Selenium results in increased expression of CREB3 mRNA

NCBI chr 9:35,732,666...35,736,999
Ensembl chr 9:35,732,598...35,736,999

G

CREB binding protein

decreases expression

Selenium results in decreased expression of CREBBP mRNA

NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713

G

cysteine rich with EGF like domains 1

increases expression

Selenium results in increased expression of CRELD1 mRNA

NCBI chr 3:9,933,834...9,945,406
Ensembl chr 3:9,933,793...9,945,413

G

CREB regulated transcription coactivator 1

increases expression

Selenium results in increased expression of CRTC1 mRNA

NCBI chr19:18,683,680...18,782,333
Ensembl chr19:18,683,678...18,782,333

G

crystallin beta-gamma domain containing 2

increases expression
multiple interactions

Selenium results in increased expression of CRYBG2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of CRYBG2 mRNA

NCBI chr 1:26,321,865...26,354,130
Ensembl chr 1:26,321,698...26,360,080

G

colony stimulating factor 1

increases expression

Selenium results in increased expression of CSF1 mRNA

NCBI chr 1:109,910,506...109,930,992
Ensembl chr 1:109,910,242...109,930,992

G

C-terminal Src kinase

increases expression

Selenium results in increased expression of CSK mRNA

NCBI chr15:74,782,080...74,803,197
Ensembl chr15:74,782,080...74,803,197

G

casein kinase 1 alpha 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1A1 mRNA
Selenium results in decreased expression of CSNK1A1 mRNA

NCBI chr 5:149,492,982...149,551,439
Ensembl chr 5:149,492,982...149,551,471

G

casein kinase 1 epsilon

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CSNK1E mRNA
Selenium results in increased expression of CSNK1E mRNA

NCBI chr22:38,290,691...38,318,084
Ensembl chr22:38,290,691...38,318,084

G

casein kinase 2 alpha 1

decreases expression

Selenium results in decreased expression of CSNK2A1 mRNA

NCBI chr20:472,498...543,790
Ensembl chr20:472,498...543,835

G

casein kinase 2 beta

increases expression

Selenium results in increased expression of CSNK2B mRNA

NCBI chr 6:31,666,080...31,670,067
Ensembl chr 6:31,665,227...31,670,343

G

chondroitin sulfate proteoglycan 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of CSPG4 mRNA

NCBI chr15:75,674,322...75,713,466
Ensembl chr15:75,674,322...75,712,848

G

centrosome and spindle pole associated protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of CSPP1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of CSPP1 mRNA

NCBI chr 8:67,064,368...67,196,614
Ensembl chr 8:67,062,417...67,196,778

G

cystatin C

increases expression

Selenium results in increased expression of CST3 mRNA

NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473

G

cystatin A

decreases expression

Selenium results in decreased expression of CSTA mRNA

NCBI chr 3:122,325,248...122,341,969
Ensembl chr 3:122,325,248...122,341,969

G

C-terminal binding protein 1

increases expression

Selenium results in increased expression of CTBP1 mRNA

NCBI chr 4:1,211,445...1,250,355
Ensembl chr 4:1,211,445...1,250,333

G

C-terminal binding protein 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTBP2 mRNA
Selenium results in decreased expression of CTBP2 mRNA

NCBI chr10:124,984,317...125,162,463
Ensembl chr10:124,984,317...125,161,170

G

chitobiase

decreases expression

Selenium results in decreased expression of CTBS mRNA

NCBI chr 1:84,549,611...84,574,440
Ensembl chr 1:84,549,611...84,574,480

G

CTD nuclear envelope phosphatase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of CTDNEP1 mRNA
Selenium results in increased expression of CTDNEP1 mRNA

NCBI chr17:7,243,591...7,251,978
Ensembl chr17:7,243,591...7,252,491

G

catenin alpha 1

increases expression

Selenium results in increased expression of CTNNA1 mRNA

NCBI chr 5:138,753,425...138,935,034
Ensembl chr 5:138,610,967...138,935,034

G

catenin beta like 1

increases expression

Selenium results in increased expression of CTNNBL1 mRNA

NCBI chr20:37,694,030...37,872,118
Ensembl chr20:37,694,030...37,872,129

G

cathepsin A

increases expression

Selenium results in increased expression of CTSA mRNA

NCBI chr20:45,891,335...45,898,820
Ensembl chr20:45,890,144...45,898,949

G

cathepsin B

increases expression

Selenium results in increased expression of CTSB mRNA

NCBI chr 8:11,842,524...11,868,087
Ensembl chr 8:11,842,524...11,869,533

G

cathepsin O

decreases expression

Selenium results in decreased expression of CTSO mRNA

NCBI chr 4:155,924,118...155,953,866
Ensembl chr 4:155,921,580...155,953,912

G

CUE domain containing 2

increases expression

Selenium results in increased expression of CUEDC2 mRNA

NCBI chr10:102,423,249...102,432,574
Ensembl chr10:102,423,245...102,432,584

G

cullin 3

decreases expression

Selenium results in decreased expression of CUL3 mRNA

NCBI chr 2:224,470,150...224,585,363
Ensembl chr 2:224,470,150...224,585,397

G

cullin 4A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of CUL4A mRNA

NCBI chr13:113,208,193...113,267,108
Ensembl chr13:113,208,193...113,267,108

G

cullin 7

increases expression

Selenium results in increased expression of CUL7 mRNA

NCBI chr 6:43,037,617...43,053,851
Ensembl chr 6:43,037,617...43,053,943

G

cutC copper transporter

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of CUTC mRNA
Selenium results in decreased expression of CUTC mRNA

NCBI chr10:99,732,234...99,756,134
Ensembl chr10:99,702,558...99,756,134

G

C-X-C motif chemokine ligand 1

increases expression

Selenium results in increased expression of CXCL1 mRNA

NCBI chr 4:73,869,393...73,871,308
Ensembl chr 4:73,869,393...73,871,308

G

C-X-C motif chemokine ligand 2

increases expression

Selenium results in increased expression of CXCL2 mRNA

NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196

G

C-X-C motif chemokine ligand 8

increases expression

Selenium results in increased expression of CXCL8 mRNA

NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716

G

C-X-C motif chemokine ligand 9

decreases expression

Selenium results in decreased expression of CXCL9 mRNA

NCBI chr 4:76,001,275...76,007,509
Ensembl chr 4:76,001,275...76,007,509

G

C-X-C motif chemokine receptor 4

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of CXCR4 mRNA

NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177

G

CXXC finger protein 1

increases expression

Selenium results in increased expression of CXXC1 mRNA

NCBI chr18:50,282,347...50,287,692
Ensembl chr18:50,282,343...50,287,839

G

cytochrome b561 family member D2

increases expression

Selenium results in increased expression of CYB561D2 mRNA

NCBI chr 3:50,350,862...50,368,197
Ensembl chr 3:50,350,845...50,358,460

G

cytochrome c, somatic

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of CYCS mRNA]; Selenium inhibits the reaction [nickel sulfate results in increased expression of CYCS protein]

PMID:27920530 PMID:34612572

NCBI chr 7:25,118,656...25,125,260
Ensembl chr 7:25,118,656...25,125,260

G

cytochrome P450 family 1 subfamily A member 1

multiple interactions

Selenium promotes the reaction [Plant Extracts results in increased activity of CYP1A1 protein]

NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536

G

cytochrome P450 family 1 subfamily A member 2

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]

NCBI chr15:74,748,845...74,756,607
Ensembl chr15:74,748,845...74,756,607

G

cytochrome P450 family 27 subfamily A member 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP27A1 mRNA]

NCBI chr 2:218,782,147...218,815,293
Ensembl chr 2:218,781,749...218,815,293

G

cytochrome P450 family 2 subfamily A member 6

increases expression

Selenium deficiency results in increased expression of CYP2A5 mRNA

NCBI chr19:40,843,541...40,850,447
Ensembl chr19:40,843,541...40,850,447

G

cytochrome P450 family 2 subfamily B member 6

increases expression

Selenium deficiency results in increased expression of CYP2B10 mRNA

NCBI chr19:40,991,282...41,018,398
Ensembl chr19:40,991,282...41,018,398

G

cytochrome P450 family 2 subfamily E member 1

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]

NCBI chr10:133,527,363...133,539,123
Ensembl chr10:133,520,406...133,561,220

G

cytochrome P450 family 3 subfamily A member 4

decreases expression

Selenium results in decreased expression of CYP3A4 mRNA

NCBI chr 7:99,756,967...99,784,184
Ensembl chr 7:99,756,960...99,784,248

G

cytochrome P450 family 3 subfamily A member 5

decreases expression

Selenium results in decreased expression of CYP3A5 mRNA

NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996

G

cytochrome P450 family 4 subfamily B member 1

increases expression

Selenium deficiency results in increased expression of CYP4B1 mRNA

NCBI chr 1:46,799,046...46,819,413
Ensembl chr 1:46,757,838...46,819,413

G

cytochrome P450 family 7 subfamily A member 1

multiple interactions

[Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP7A1 mRNA]

PMID:30031400 PMID:36464106

NCBI chr 8:58,490,178...58,500,163
Ensembl chr 8:58,490,178...58,500,163

G

cytochrome P450 family 7 subfamily B member 1

increases expression

Selenium deficiency results in increased expression of CYP7B1 mRNA; Selenium results in increased expression of CYP7B1 mRNA

NCBI chr 8:64,586,575...64,798,737
Ensembl chr 8:64,587,763...64,798,737

G

cytochrome P450 family 8 subfamily B member 1

increases expression
multiple interactions

Selenium deficiency results in increased expression of CYP8B1 mRNA; Selenium results in increased expression of CYP8B1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in decreased expression of CYP8B1 mRNA]

PMID:16170372 PMID:36464106

NCBI chr 3:42,872,192...42,875,879
Ensembl chr 3:42,856,005...42,875,898

G

dishevelled associated activator of morphogenesis 1

decreases expression

Selenium results in decreased expression of DAAM1 mRNA

NCBI chr14:59,188,667...59,371,405
Ensembl chr14:59,188,646...59,371,405

G

dishevelled binding antagonist of beta catenin 1

decreases expression

Selenium results in decreased expression of DACT1 mRNA

NCBI chr14:58,634,061...58,648,321
Ensembl chr14:58,633,967...58,648,321

G

defender against cell death 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA

NCBI chr14:22,564,907...22,589,224
Ensembl chr14:22,564,907...22,589,224

G

death associated protein kinase 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DAPK3 mRNA
Selenium results in increased expression of DAPK3 mRNA

NCBI chr19:3,958,453...3,971,099
Ensembl chr19:3,958,453...3,971,123

G

dynactin subunit 1

increases expression

Selenium results in increased expression of DCTN1 mRNA

NCBI chr 2:74,361,155...74,391,866
Ensembl chr 2:74,361,154...74,392,087

G

dicarbonyl and L-xylulose reductase

increases expression

Selenium results in increased expression of DCXR mRNA

NCBI chr17:82,035,858...82,037,697
Ensembl chr17:82,035,136...82,037,709

G

DDAH family member 2, ADMA-independent

increases expression

Selenium results in increased expression of DDAH2 mRNA

NCBI chr 6:31,727,040...31,730,263
Ensembl chr 6:31,727,038...31,730,617

G

dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

increases expression

Selenium results in increased expression of DDOST mRNA

NCBI chr 1:20,651,777...20,661,369
Ensembl chr 1:20,651,767...20,661,544

G

DEAD-box helicase 17

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DDX17 mRNA
Selenium results in decreased expression of DDX17 mRNA

NCBI chr22:38,483,438...38,506,311
Ensembl chr22:38,483,438...38,507,660

G

DEAD-box helicase 18

decreases expression
multiple interactions

Selenium results in decreased expression of DDX18 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of DDX18 mRNA

NCBI chr 2:117,814,691...117,832,377
Ensembl chr 2:117,814,691...117,832,377

G

DEAD-box helicase 24

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX24 mRNA
Selenium results in decreased expression of DDX24 mRNA

NCBI chr14:94,048,287...94,081,202
Ensembl chr14:94,048,287...94,081,202

G

DExD-box helicase 39B

decreases expression
increases expression

Selenium results in decreased expression of DDX39B mRNA
Selenium results in increased expression of DDX39B mRNA

NCBI chr 6:31,530,226...31,542,003
Ensembl chr 6:31,530,219...31,542,448

G

DEAD-box helicase 3 Y-linked

decreases expression

Selenium results in decreased expression of DDX3Y mRNA

NCBI chr Y:12,903,999...12,920,478
Ensembl chr Y:12,904,108...12,920,478

G

DEAD-box helicase 41

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DDX41 mRNA
Selenium results in increased expression of DDX41 mRNA

NCBI chr 5:177,511,577...177,516,961
Ensembl chr 5:177,511,577...177,516,961

G

DEAD-box helicase 49

increases expression

Selenium results in increased expression of DDX49 mRNA

NCBI chr19:18,919,715...18,928,630
Ensembl chr19:18,919,705...18,929,189

G

2,4-dienoyl-CoA reductase 2

increases expression

Selenium deficiency results in increased expression of DECR2 mRNA

NCBI chr16:401,885...412,482
Ensembl chr16:401,858...412,487

G

death effector domain containing

increases expression

Selenium results in increased expression of DEDD mRNA

NCBI chr 1:161,120,974...161,132,667
Ensembl chr 1:161,120,974...161,132,688

G

delta 4-desaturase, sphingolipid 1

decreases expression

Selenium results in decreased expression of DEGS1 mRNA

NCBI chr 1:224,183,240...224,193,441
Ensembl chr 1:224,175,756...224,193,441

G

DENND10 pseudogene 1

decreases expression

Selenium results in decreased expression of DENND10P1 mRNA

NCBI chr X:130,494,941...130,497,448
Ensembl chr X:130,495,159...130,496,232

G

DENN domain containing 2B

increases expression

Selenium results in increased expression of DENND2B mRNA

NCBI chr11:8,693,352...8,910,951
Ensembl chr11:8,693,351...8,910,951

G

deoxyribose-phosphate aldolase

decreases expression

Selenium results in decreased expression of DERA mRNA

NCBI chr12:15,911,332...16,037,381
Ensembl chr12:15,911,302...16,037,381

G

desmin

increases expression

Selenium results in increased expression of DES mRNA

NCBI chr 2:219,418,377...219,426,734
Ensembl chr 2:219,418,377...219,426,735

G

desumoylating isopeptidase 2

decreases expression

Selenium results in decreased expression of DESI2 mRNA

NCBI chr 1:244,653,126...244,709,033
Ensembl chr 1:244,653,103...244,709,033

G

DiGeorge syndrome critical region gene 6

increases expression

Selenium results in increased expression of DGCR6 mRNA

NCBI chr22:18,906,223...18,912,088
Ensembl chr22:18,906,028...18,914,238

G

DGCR8 microprocessor complex subunit

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of DGCR8 mRNA
Selenium results in increased expression of DGCR8 mRNA

NCBI chr22:20,080,241...20,111,872
Ensembl chr22:20,080,221...20,111,877

G

24-dehydrocholesterol reductase

increases expression

Selenium results in increased expression of DHCR24 mRNA

NCBI chr 1:54,849,627...54,887,195
Ensembl chr 1:54,849,627...54,887,195

G

7-dehydrocholesterol reductase

increases expression

Selenium results in increased expression of DHCR7 mRNA

NCBI chr11:71,434,411...71,448,393
Ensembl chr11:71,428,193...71,452,868

G

deoxyhypusine synthase

increases expression
multiple interactions

Selenium results in increased expression of DHPS mRNA
[Selenium co-treated with Vitamin E] results in increased expression of DHPS mRNA

NCBI chr19:12,672,470...12,681,880
Ensembl chr19:12,675,717...12,681,880

G

dehydrogenase/reductase 4

increases expression

Selenium results in increased expression of DHRS4 mRNA

NCBI chr14:23,953,770...23,969,279
Ensembl chr14:23,953,734...23,969,279

G

dehydrogenase/reductase 7B

increases expression

Selenium results in increased expression of DHRS7B mRNA

NCBI chr17:21,126,964...21,191,420
Ensembl chr17:21,123,364...21,193,265

G

DExH-box helicase 30

increases expression

Selenium results in increased expression of DHX30 mRNA

NCBI chr 3:47,803,138...47,850,193
Ensembl chr 3:47,802,909...47,850,195

G

dicer 1, ribonuclease III

decreases expression

Selenium results in decreased expression of DICER1 mRNA

NCBI chr14:95,086,228...95,158,010
Ensembl chr14:95,086,228...95,158,010

G

iodothyronine deiodinase 1

decreases expression
increases expression
affects expression
increases activity
multiple interactions

Selenium deficiency results in decreased expression of DIO1 mRNA
Selenium results in increased expression of DIO1 mRNA
Selenium deficiency affects the expression of DIO1 mRNA
Selenium results in increased activity of DIO1 protein
Selenium inhibits the reaction [Iodine results in decreased activity of DIO1 protein]; Selenium inhibits the reaction [Iodine results in decreased expression of DIO1 mRNA]; Selenium inhibits the reaction [potassium iodate results in decreased activity of DIO1 protein]

PMID:16170372 PMID:16271152 PMID:16874406 PMID:16959840 PMID:17044649 More...

NCBI chr 1:53,894,187...53,911,086
Ensembl chr 1:53,891,239...53,911,086

G

iodothyronine deiodinase 2

multiple interactions
increases activity

Selenium results in increased expression of and results in increased activity of DIO2 protein
Selenium results in increased activity of DIO2 protein

PMID:11425850 PMID:15471965

NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757

G

disco interacting protein 2 homolog C

decreases expression

Selenium results in decreased expression of DIP2C mRNA

NCBI chr10:274,201...689,668
Ensembl chr10:274,201...689,668

G

discs large MAGUK scaffold protein 1

decreases expression

Selenium results in decreased expression of DLG1 mRNA

NCBI chr 3:197,042,560...197,299,321
Ensembl chr 3:197,042,560...197,299,330

G

dimethylglycine dehydrogenase

affects abundance

DMGDH gene SNP affects the abundance of Selenium

NCBI chr 5:78,997,564...79,069,674
Ensembl chr 5:78,997,564...79,236,038

G

cyclin D binding myb like transcription factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of DMTF1 mRNA
Selenium results in decreased expression of DMTF1 mRNA

NCBI chr 7:87,152,453...87,196,325
Ensembl chr 7:87,152,409...87,196,337

G

DM1 locus, WD repeat containing

increases expression

Selenium results in increased expression of DMWD mRNA

NCBI chr19:45,782,947...45,792,845
Ensembl chr19:45,782,947...45,792,845

G

Dmx like 2

decreases expression

Selenium results in decreased expression of DMXL2 mRNA

NCBI chr15:51,447,791...51,622,771
Ensembl chr15:51,447,711...51,622,833

G

DNA replication helicase/nuclease 2

decreases expression

Selenium results in decreased expression of DNA2 mRNA

NCBI chr10:68,414,064...68,472,521
Ensembl chr10:68,414,064...68,472,121

G

DnaJ heat shock protein family (Hsp40) member A3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJA3 mRNA
Selenium results in decreased expression of DNAJA3 mRNA

NCBI chr16:4,425,868...4,456,775
Ensembl chr16:4,425,805...4,456,775

G

DnaJ heat shock protein family (Hsp40) member B3

multiple interactions
decreases expression

[Selenium co-treated with Selenium] results in decreased expression of DNAJB3 mRNA
Selenium deficiency results in decreased expression of DNAJB3 mRNA

NCBI chr 2:233,742,750...233,743,998
Ensembl chr 2:233,743,188...233,743,916
Ensembl chr 2:233,743,188...233,743,916

G

DnaJ heat shock protein family (Hsp40) member B4

decreases expression

Selenium results in decreased expression of DNAJB4 mRNA

NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964

G

DnaJ heat shock protein family (Hsp40) member C2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC2 mRNA

NCBI chr 7:103,312,289...103,344,767
Ensembl chr 7:103,312,289...103,344,830

G

DnaJ heat shock protein family (Hsp40) member C7

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of DNAJC7 mRNA

NCBI chr17:41,976,435...42,017,439
Ensembl chr17:41,976,421...42,021,376

G

DnaJ heat shock protein family (Hsp40) member C9

decreases expression

Selenium results in decreased expression of DNAJC9 mRNA

NCBI chr10:73,232,272...73,247,255
Ensembl chr10:73,183,362...73,247,255

G

DNA methyltransferase 1

affects activity

Selenium affects the activity of DNMT1 protein

NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,342...10,231,286

G

aspartyl aminopeptidase

increases expression

Selenium results in increased expression of DNPEP mRNA

NCBI chr 2:219,372,043...219,400,007
Ensembl chr 2:219,372,043...219,400,022

G

deoxyhypusine hydroxylase

increases expression
multiple interactions

Selenium results in increased expression of DOHH mRNA
[Selenium co-treated with Vitamin E] results in increased expression of DOHH mRNA

NCBI chr19:3,490,824...3,500,674
Ensembl chr19:3,490,821...3,500,674

G

dolichyldiphosphatase 1

increases expression

Selenium results in increased expression of DOLPP1 mRNA

NCBI chr 9:129,081,111...129,090,438
Ensembl chr 9:129,081,111...129,090,438

G

dihydropyrimidine dehydrogenase

decreases expression

Selenium results in decreased expression of DPYD mRNA

NCBI chr 1:97,077,743...97,921,059
Ensembl chr 1:97,077,743...97,995,000

G

down-regulator of transcription 1

decreases expression

Selenium results in decreased expression of DR1 mRNA

NCBI chr 1:93,345,907...93,369,493
Ensembl chr 1:93,345,907...93,369,493

G

developmentally regulated GTP binding protein 2

increases expression

Selenium results in increased expression of DRG2 mRNA

NCBI chr17:18,087,948...18,107,969
Ensembl chr17:18,087,892...18,107,970

G

desmocollin 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of DSC2 mRNA
Selenium results in decreased expression of DSC2 mRNA

NCBI chr18:31,058,840...31,102,421
Ensembl chr18:31,058,840...31,102,522

G

dermatan sulfate epimerase

decreases expression

Selenium results in decreased expression of DSE mRNA

NCBI chr 6:116,254,171...116,444,861
Ensembl chr 6:116,254,173...116,444,861

G

dual oxidase 1

increases expression

Selenium results in increased expression of DUOX1 mRNA

NCBI chr15:45,129,994...45,165,574
Ensembl chr15:45,129,933...45,165,576

G

dual specificity phosphatase 8

increases expression

Selenium results in increased expression of DUSP8 mRNA

NCBI chr11:1,554,051...1,572,848
Ensembl chr11:1,554,051...1,572,271

G

decapping exoribonuclease

increases expression

Selenium results in increased expression of DXO mRNA

NCBI chr 6:31,969,815...31,972,138
Ensembl chr 6:31,969,810...31,972,290

G

dymeclin

decreases expression

Selenium results in decreased expression of DYM mRNA

NCBI chr18:49,036,387...49,460,645
Ensembl chr18:49,036,387...49,461,347

G

dynein cytoplasmic 1 heavy chain 1

increases expression

Selenium results in increased expression of DYNC1H1 mRNA

NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443

G

dynein light chain roadblock-type 1

decreases expression

Selenium results in decreased expression of DYNLRB1 mRNA

NCBI chr20:34,515,602...34,540,958
Ensembl chr20:34,516,395...34,540,958

G

E2F transcription factor 1

increases expression

Selenium results in increased expression of E2F1 mRNA

NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385

G

E2F transcription factor 4

increases expression

Selenium results in increased expression of E2F4 mRNA

NCBI chr16:67,192,155...67,198,918
Ensembl chr16:67,192,155...67,198,918

G

E2F transcription factor 6

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of E2F6 mRNA
Selenium results in decreased expression of E2F6 mRNA

NCBI chr 2:11,444,375...11,466,161
Ensembl chr 2:11,444,375...11,466,177

G

E4F transcription factor 1

increases expression

Selenium results in increased expression of E4F1 mRNA

NCBI chr16:2,223,591...2,235,742
Ensembl chr16:2,223,580...2,235,742

G

extracellular matrix protein 2

decreases expression

Selenium results in decreased expression of ECM2 mRNA

NCBI chr 9:92,493,547...92,559,106
Ensembl chr 9:92,493,554...92,536,655

G

ECSIT signaling integrator

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ECSIT mRNA
Selenium results in increased expression of ECSIT mRNA

NCBI chr19:11,505,929...11,529,134
Ensembl chr19:11,505,929...11,529,172

G

endothelial differentiation related factor 1

increases expression

Selenium results in increased expression of EDF1 mRNA

NCBI chr 9:136,862,119...136,866,308
Ensembl chr 9:136,862,119...136,866,308

G

endothelin receptor type A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of EDNRA mRNA
Selenium results in decreased expression of EDNRA mRNA

NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954

G

eukaryotic translation elongation factor 1 alpha 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EEF1A2 mRNA
Selenium results in increased expression of EEF1A2 mRNA

NCBI chr20:63,488,014...63,499,083
Ensembl chr20:63,488,013...63,499,239

G

eukaryotic translation elongation factor 1 delta

increases expression

Selenium results in increased expression of EEF1D mRNA

NCBI chr 8:143,579,728...143,597,415
Ensembl chr 8:143,579,697...143,599,541

G

EF-hand calcium binding domain 14

increases expression

Selenium results in increased expression of EFCAB14 mRNA

NCBI chr 1:46,675,159...46,719,114
Ensembl chr 1:46,674,659...46,719,146

G

EGF containing fibulin extracellular matrix protein 2

increases expression

Selenium results in increased expression of EFEMP2 mRNA

NCBI chr11:65,866,441...65,872,800
Ensembl chr11:65,866,441...65,873,592

G

EF-hand domain containing 1

decreases expression

Selenium results in decreased expression of EFHC1 mRNA

NCBI chr 6:52,420,342...52,497,198
Ensembl chr 6:52,362,123...52,529,886

G

EF-hand domain family member D2

increases expression

Selenium results in increased expression of EFHD2 mRNA

NCBI chr 1:15,409,888...15,430,339
Ensembl chr 1:15,409,888...15,430,339

G

epidermal growth factor

multiple interactions

Selenium inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Selenium inhibits the reaction [EGF protein results in increased abundance of Peroxides]

NCBI chr 4:109,912,883...110,013,766
Ensembl chr 4:109,912,883...110,013,766

G

epidermal growth factor receptor

decreases expression

Selenium results in decreased expression of EGFR mRNA

NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628

G

early growth response 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of EGR1 mRNA

NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303

G

EH domain binding protein 1

decreases expression

Selenium results in decreased expression of EHBP1 mRNA

NCBI chr 2:62,673,878...63,046,487
Ensembl chr 2:62,673,851...63,046,487

G

EH domain containing 2

increases expression

Selenium results in increased expression of EHD2 mRNA

NCBI chr19:47,713,422...47,743,134
Ensembl chr19:47,713,422...47,743,134

G

eukaryotic translation initiation factor 1B

decreases expression

Selenium results in decreased expression of EIF1B mRNA

NCBI chr 3:40,309,707...40,312,424
Ensembl chr 3:40,309,707...40,312,424

G

eukaryotic translation initiation factor 2 alpha kinase 2

decreases expression

Selenium results in decreased expression of EIF2AK2 mRNA

NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522

G

eukaryotic translation initiation factor 3 subunit A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of EIF3A mRNA

NCBI chr10:119,033,670...119,080,817
Ensembl chr10:119,033,670...119,080,817

G

eukaryotic translation initiation factor 3 subunit B

increases expression

Selenium results in increased expression of EIF3B mRNA

NCBI chr 7:2,354,086...2,380,745
Ensembl chr 7:2,354,086...2,380,745

G

eukaryotic translation initiation factor 3 subunit C

increases expression

Selenium results in increased expression of EIF3C mRNA

NCBI chr16:28,688,558...28,735,730
Ensembl chr16:28,688,558...28,735,727

G

eukaryotic translation initiation factor 4 gamma 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EIF4G1 mRNA
Selenium results in increased expression of EIF4G1 mRNA

NCBI chr 3:184,314,606...184,335,358
Ensembl chr 3:184,314,495...184,335,358

G

eukaryotic translation initiation factor 5A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of EIF5A mRNA

NCBI chr17:7,306,999...7,312,463
Ensembl chr17:7,306,999...7,312,463

G

eukaryotic translation initiation factor 5B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IF2 mRNA
Selenium results in decreased expression of IF2 mRNA

NCBI chr 2:99,337,389...99,401,326
Ensembl chr 2:99,337,389...99,401,326

G

eukaryotic translation initiation factor 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EIF6 mRNA
Selenium results in increased expression of EIF6 mRNA

NCBI chr20:35,278,906...35,284,772
Ensembl chr20:35,278,907...35,284,985

G

elongin A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ELOA mRNA

NCBI chr 1:23,743,471...23,762,059
Ensembl chr 1:23,743,448...23,762,059

G

elongator acetyltransferase complex subunit 1

decreases expression

Selenium results in decreased expression of ELP1 mRNA

NCBI chr 9:108,867,517...108,934,124
Ensembl chr 9:108,866,898...108,934,328

G

ER membrane protein complex subunit 9

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of EMC9 mRNA

NCBI chr14:24,138,965...24,141,591
Ensembl chr14:24,138,959...24,141,591

G

elastin microfibril interfacer 1

increases expression

Selenium results in increased expression of EMILIN1 mRNA

NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403

G

EMAP like 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of EML2 mRNA
Selenium results in increased expression of EML2 mRNA

NCBI chr19:45,609,400...45,645,629
Ensembl chr19:45,606,994...45,645,602

G

epithelial membrane protein 2

increases expression

Selenium results in increased expression of EMP2 mRNA

NCBI chr16:10,528,422...10,580,598
Ensembl chr16:10,528,422...10,580,632

G

epithelial membrane protein 3 (MAM blood group)

increases expression

Selenium results in increased expression of EMP3 mRNA

NCBI chr19:48,325,552...48,330,553
Ensembl chr19:48,321,509...48,330,553

G

EMSY transcriptional repressor, BRCA2 interacting

decreases expression

Selenium results in decreased expression of EMSY mRNA

NCBI chr11:76,445,018...76,553,031
Ensembl chr11:76,444,923...76,553,031

G

endonuclease G

increases expression

Selenium results in increased expression of ENDOG mRNA

NCBI chr 9:128,818,500...128,822,676
Ensembl chr 9:128,818,500...128,822,676

G

endoglin

increases expression

Selenium results in increased expression of ENG mRNA

NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,815,013...127,854,658

G

enolase 2

increases expression

Selenium results in increased expression of ENO2 mRNA

NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698

G

ectonucleotide pyrophosphatase/phosphodiesterase 1

decreases expression

Selenium results in decreased expression of ENPP1 mRNA

NCBI chr 6:131,808,020...131,895,155
Ensembl chr 6:131,808,016...131,895,155

G

endothelium and lymphocyte associated ASCH domain 1

decreases expression

Selenium results in decreased expression of EOLA1 mRNA

NCBI chr X:149,540,601...149,555,345
Ensembl chr X:149,540,355...149,550,510

G

erythrocyte membrane protein band 4.1 like 4B

decreases expression

Selenium results in decreased expression of EPB41L4B mRNA

NCBI chr 9:109,171,974...109,321,059
Ensembl chr 9:109,171,974...109,321,059

G

EPH receptor B6

increases expression

Selenium results in increased expression of EPHB6 mRNA

NCBI chr 7:142,855,076...142,871,093
Ensembl chr 7:142,855,061...142,871,094

G

epoxide hydrolase 2

increases expression

Selenium results in increased expression of EPHX2 mRNA

NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564

G

epsin 2

increases expression

Selenium results in increased expression of EPN2 mRNA

NCBI chr17:19,237,366...19,336,715
Ensembl chr17:19,215,615...19,336,715

G

erb-b2 receptor tyrosine kinase 2

increases expression
multiple interactions

Selenium results in increased expression of ERBB2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ERBB2 mRNA

NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426

G

ERCC excision repair 1, endonuclease non-catalytic subunit

increases expression

Selenium results in increased expression of ERCC1 mRNA

NCBI chr19:45,407,334...45,451,547
Ensembl chr19:45,407,334...45,478,828

G

ERGIC and golgi 3

increases expression

Selenium results in increased expression of ERGIC3 mRNA

NCBI chr20:35,542,078...35,557,634
Ensembl chr20:35,542,038...35,557,634

G

estrogen receptor 1

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of ESR1 mRNA]

NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619

G

epithelial splicing regulatory protein 2

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ESRP2 mRNA

NCBI chr16:68,229,033...68,236,127
Ensembl chr16:68,229,033...68,238,102

G

ess-2 splicing factor homolog

increases expression

Selenium results in increased expression of ESS2 mRNA

NCBI chr22:19,130,279...19,144,651
Ensembl chr22:19,130,279...19,144,684

G

EvC ciliary complex subunit 1

increases expression

Selenium results in increased expression of EVC mRNA

NCBI chr 4:5,711,201...5,829,057
Ensembl chr 4:5,711,201...5,814,305

G

ecotropic viral integration site 5

decreases expression

Selenium results in decreased expression of EVI5 mRNA

NCBI chr 1:92,508,696...92,792,410
Ensembl chr 1:92,508,696...92,792,404

G

EWS RNA binding protein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of EWSR1 mRNA
Selenium results in increased expression of EWSR1 mRNA

NCBI chr22:29,268,268...29,300,521
Ensembl chr22:29,268,009...29,300,525

G

exocyst complex component 3

increases expression

Selenium results in increased expression of SEC6 mRNA

NCBI chr 5:443,176...467,290
Ensembl chr 5:443,175...471,937

G

exosome component 4

increases expression

Selenium results in increased expression of EXOSC4 mRNA

NCBI chr 8:144,064,056...144,080,648
Ensembl chr 8:144,078,648...144,080,648

G

exosome component 8

decreases expression

Selenium results in decreased expression of EXOSC8 mRNA

NCBI chr13:37,000,786...37,009,614
Ensembl chr13:36,998,816...37,025,881

G

exostosin glycosyltransferase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of EXT1 mRNA

NCBI chr 8:117,794,490...118,111,826
Ensembl chr 8:117,794,490...118,111,826

G

exostosin glycosyltransferase 2

decreases expression

Selenium results in decreased expression of EXT2 mRNA

NCBI chr11:44,095,678...44,251,962
Ensembl chr11:44,095,648...44,251,962

G

EYA transcriptional coactivator and phosphatase 2

increases expression

Selenium results in increased expression of EYA2 mRNA

NCBI chr20:46,894,843...47,188,844
Ensembl chr20:46,894,624...47,188,844

G

ezrin

decreases expression
multiple interactions

Selenium results in decreased expression of EZR mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of EZR mRNA

NCBI chr 6:158,765,748...158,819,368
Ensembl chr 6:158,765,741...158,819,368

G

F11 receptor

increases expression

Selenium results in increased expression of F11R mRNA

NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175

G

coagulation factor II thrombin receptor

decreases expression
multiple interactions

Selenium results in decreased expression of F2R mRNA
[Selenium co-treated with Vitamin E] results in increased expression of F2R mRNA

NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770

G

fatty acid amide hydrolase

increases expression

Selenium results in increased expression of FAAH mRNA

NCBI chr 1:46,394,317...46,413,845
Ensembl chr 1:46,394,317...46,413,848

G

Fas associated via death domain

multiple interactions
increases expression

[Doxorubicin co-treated with Selenium] promotes the reaction [FADD protein binds to CASP8 protein]; [Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FADD mRNA]; Selenium analog inhibits the reaction [Diazinon results in decreased expression of FADD mRNA]
Selenium results in increased expression of FADD protein

PMID:17970047 PMID:27920530

NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390

G

fatty acid desaturase 3

increases expression

Selenium results in increased expression of FADS3 mRNA

NCBI chr11:61,873,526...61,892,224
Ensembl chr11:61,873,519...61,892,051

G

family with sequence similarity 107 member A

increases expression

Selenium results in increased expression of FAM107A mRNA

NCBI chr 3:58,564,117...58,627,610
Ensembl chr 3:58,564,117...58,627,610

G

FAM111 trypsin like peptidase A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FAM111A mRNA
Selenium results in decreased expression of FAM111A mRNA

NCBI chr11:59,142,856...59,155,039
Ensembl chr11:59,142,748...59,155,039

G

family with sequence similarity 149 member A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FAM149A mRNA
Selenium results in decreased expression of FAM149A mRNA

NCBI chr 4:186,104,704...186,175,337
Ensembl chr 4:186,104,419...186,175,337

G

family with sequence similarity 32 member A

increases expression

Selenium results in increased expression of FAM32A mRNA

NCBI chr19:16,185,410...16,192,046
Ensembl chr19:16,185,380...16,192,046

G

FAM3 metabolism regulating signaling molecule A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FAM3A mRNA
Selenium results in increased expression of FAM3A mRNA

NCBI chr X:154,506,171...154,516,232
Ensembl chr X:154,506,159...154,516,242

G

family with sequence similarity 50 member A

increases expression

Selenium results in increased expression of FAM50A mRNA

NCBI chr X:154,444,141...154,450,654
Ensembl chr X:154,444,141...154,450,654

G

family with sequence similarity 53 member B

increases expression

Selenium results in increased expression of FAM53B mRNA

NCBI chr10:124,619,292...124,744,378
Ensembl chr10:124,619,292...124,744,378

G

FANCD2 and FANCI associated nuclease 1

decreases expression

Selenium results in decreased expression of FAN1 mRNA

NCBI chr15:30,903,852...30,943,108
Ensembl chr15:30,890,559...30,943,108

G

FERM, ARH/RhoGEF and pleckstrin domain protein 1

increases expression

Selenium results in increased expression of FARP1 mRNA

NCBI chr13:98,142,589...98,455,176
Ensembl chr13:98,142,562...98,455,176

G

phenylalanyl-tRNA synthetase subunit alpha

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of FARSA mRNA
Selenium results in increased expression of FARSA mRNA

NCBI chr19:12,922,479...12,933,711
Ensembl chr19:12,922,479...12,934,037

G

Fas cell surface death receptor

multiple interactions

[Doxorubicin co-treated with Selenium] promotes the reaction [FAS protein binds to CASP8 protein]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of FAS mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of FAS mRNA]

PMID:17970047 PMID:27920530

NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605

G

Fas ligand

multiple interactions

[Selenium analog co-treated with Magnesium Oxide analog] promotes the reaction [Diazinon results in decreased expression of FASLG mRNA]

NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876

G

fatty acid synthase

increases expression
multiple interactions

Selenium results in increased expression of FASN mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of FASN mRNA]

PMID:19022953 PMID:19244175 PMID:36464106

NCBI chr17:82,078,338...82,098,236
Ensembl chr17:82,078,338...82,098,294

G

FAT atypical cadherin 4

decreases expression

Selenium results in decreased expression of FAT4 mRNA

NCBI chr 4:125,314,955...125,492,932
Ensembl chr 4:125,314,918...125,492,932

G

fatty acid hydroxylase domain containing 2

decreases expression

Selenium results in decreased expression of FAXDC2 mRNA

NCBI chr 5:154,818,492...154,850,603
Ensembl chr 5:154,818,492...154,859,252

G

fibulin 1

increases expression

Selenium results in increased expression of FBLN1 mRNA

NCBI chr22:45,502,883...45,601,135
Ensembl chr22:45,502,238...45,601,135

G

fibulin 5

increases expression

Selenium results in increased expression of FBLN5 mRNA

NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,411...91,947,987

G

fructose-bisphosphatase 1

increases expression

Selenium results in increased expression of FBP1 mRNA

NCBI chr 9:94,603,133...94,640,263
Ensembl chr 9:94,603,133...94,640,249

G

F-box and leucine rich repeat protein 5

decreases expression

Selenium results in decreased expression of FBXL5 mRNA

NCBI chr 4:15,604,381...15,681,569
Ensembl chr 4:15,604,381...15,681,679

G

F-box and leucine rich repeat protein 8

increases expression

Selenium results in increased expression of FBXL8 mRNA

NCBI chr16:67,159,957...67,164,174
Ensembl chr16:67,159,932...67,164,570

G

F-box protein 11

decreases expression

Selenium results in decreased expression of FBXO11 mRNA

NCBI chr 2:47,806,920...47,906,498
Ensembl chr 2:47,789,316...47,906,498

G

F-box protein 17

increases expression

Selenium results in increased expression of FBXO17 mRNA

NCBI chr19:38,941,401...38,975,742
Ensembl chr19:38,941,401...38,975,742

G

F-box protein 2

increases expression

Selenium results in increased expression of FBXO2 mRNA

NCBI chr 1:11,648,387...11,654,429
Ensembl chr 1:11,637,018...11,655,785

G

F-box protein 28

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of FBXO28 mRNA
Selenium results in decreased expression of FBXO28 mRNA

NCBI chr 1:224,114,111...224,162,047
Ensembl chr 1:224,114,111...224,162,047

G

Fc gamma receptor and transporter

increases expression

Selenium results in increased expression of FCGRT mRNA

NCBI chr19:49,512,661...49,526,428
Ensembl chr19:49,506,816...49,526,428

G

farnesyl-diphosphate farnesyltransferase 1

increases expression

Selenium deficiency results in increased expression of FDFT1 mRNA

NCBI chr 8:11,795,582...11,839,309
Ensembl chr 8:11,795,573...11,839,395

G

ferrochelatase

decreases expression

Selenium results in decreased expression of FECH mRNA

NCBI chr18:57,544,377...57,586,702
Ensembl chr18:57,544,377...57,586,732

G

FERM domain containing kindlin 1

decreases expression

Selenium results in decreased expression of FERMT1 mRNA

NCBI chr20:6,074,845...6,123,030
Ensembl chr20:6,074,845...6,123,214

G

free fatty acid receptor 2

increases expression

Selenium results in increased expression of FFAR2 mRNA

NCBI chr19:35,448,257...35,451,767
Ensembl chr19:35,443,907...35,451,767

G

fibrinogen gamma chain

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of FGG mRNA

NCBI chr 4:154,604,136...154,612,656
Ensembl chr 4:154,604,134...154,612,967

G

formin homology 2 domain containing 3

decreases expression

Selenium results in decreased expression of FHOD3 mRNA

NCBI chr18:36,297,713...36,780,220
Ensembl chr18:36,297,713...36,780,220

G

FIG4 phosphoinositide 5-phosphatase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FIG4 mRNA
Selenium results in decreased expression of FIG4 mRNA

NCBI chr 6:109,691,296...109,825,426
Ensembl chr 6:109,690,609...109,878,098

G

fission, mitochondrial 1

increases expression

Selenium results in increased expression of FIS1 mRNA

NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316

G

FKBP prolyl isomerase 1A

increases expression
multiple interactions

Selenium results in increased expression of FKBP1A mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of FKBP1A mRNA

NCBI chr20:1,368,978...1,393,054
Ensembl chr20:1,368,977...1,393,164

G

FKBP prolyl isomerase 3

decreases expression

Selenium results in decreased expression of FKBP3 mRNA

NCBI chr14:45,115,599...45,134,481
Ensembl chr14:45,115,599...45,135,319

G

FLII actin remodeling protein

increases expression

Selenium results in increased expression of FLII mRNA

NCBI chr17:18,244,815...18,259,022
Ensembl chr17:18,244,815...18,258,738

G

filamin A

increases expression

Selenium results in increased expression of FLNA mRNA

NCBI chr X:154,348,531...154,374,634
Ensembl chr X:154,348,524...154,374,634

G

flotillin 1

increases expression

Selenium results in increased expression of FLOT1 mRNA

NCBI chr 6:30,727,709...30,742,687
Ensembl chr 6:30,727,709...30,742,732

G

flotillin 2

increases expression

Selenium results in increased expression of FLOT2 mRNA

NCBI chr17:28,879,339...28,897,733
Ensembl chr17:28,879,335...28,897,733

G

fibronectin leucine rich transmembrane protein 3

decreases expression

Selenium results in decreased expression of FLRT3 mRNA

NCBI chr20:14,322,985...14,337,612
Ensembl chr20:14,322,985...14,337,614

G

flavin containing dimethylaniline monoxygenase 5

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of FMO5 mRNA

NCBI chr 1:147,184,305...147,227,284
Ensembl chr 1:147,175,351...147,243,050

G

folate hydrolase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of FOLH1 mRNA
Selenium results in decreased expression of FOLH1 mRNA

NCBI chr11:49,145,092...49,208,602
Ensembl chr11:49,145,092...49,208,638

G

Fos proto-oncogene, AP-1 transcription factor subunit

increases expression
multiple interactions

Selenium results in increased expression of FOS mRNA; Selenium results in increased expression of FOS protein
[Selenium co-treated with Iodine] results in increased expression of FOS mRNA; [Selenium co-treated with Iodine] results in increased expression of FOS protein

PMID:12475444 PMID:12666833

NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,282,230

G

forkhead box F2

decreases expression

Selenium results in decreased expression of FOXF2 mRNA

NCBI chr 6:1,389,576...1,395,603
Ensembl chr 6:1,389,576...1,395,603

G

forkhead box O1

multiple interactions

Selenium inhibits the reaction [arsenite results in decreased phosphorylation of FOXO1 protein]

NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641

G

forkhead box O3

multiple interactions

Selenium results in decreased phosphorylation of and results in increased activity of FOXO3 protein

NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774

G

FRAT regulator of WNT signaling pathway 1

increases expression

Selenium results in increased expression of FRAT1 mRNA

NCBI chr10:97,319,271...97,321,915
Ensembl chr10:97,319,271...97,321,915

G

follicle stimulating hormone subunit beta

multiple interactions

Selenium inhibits the reaction [Cadmium Chloride results in decreased expression of FSHB protein]

NCBI chr11:30,231,014...30,235,194
Ensembl chr11:30,231,014...30,235,261

G

ferritin light chain

increases expression

Selenium results in increased expression of FTL mRNA

NCBI chr19:48,965,309...48,966,879
Ensembl chr19:48,965,309...48,966,879

G

FUS RNA binding protein

increases expression

Selenium results in increased expression of FUS mRNA

NCBI chr16:31,180,110...31,194,871
Ensembl chr16:31,180,138...31,191,605

G

FMR1 autosomal homolog 1

decreases expression

Selenium results in decreased expression of FXR1 mRNA

NCBI chr 3:180,912,670...180,982,753
Ensembl chr 3:180,868,141...180,982,753

G

frizzled class receptor 7

decreases expression

Selenium results in decreased expression of FZD7 mRNA

NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441

G

fizzy and cell division cycle 20 related 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of FZR1 mRNA
Selenium results in increased expression of FZR1 mRNA

NCBI chr19:3,506,311...3,538,334
Ensembl chr19:3,506,311...3,538,334

G

G0/G1 switch 2

increases expression

Selenium results in increased expression of G0S2 mRNA

NCBI chr 1:209,675,412...209,676,390
Ensembl chr 1:209,675,412...209,676,390

G

growth arrest and DNA damage inducible alpha

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GADD45A mRNA

NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334

G

polypeptide N-acetylgalactosaminyltransferase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GALNT1 mRNA
Selenium results in decreased expression of GALNT1 mRNA

NCBI chr18:35,580,922...35,711,834
Ensembl chr18:35,581,117...35,711,834

G

glucosidase II alpha subunit

increases expression

Selenium results in increased expression of GANAB mRNA

NCBI chr11:62,624,829...62,646,613
Ensembl chr11:62,624,826...62,646,726

G

glyceraldehyde-3-phosphate dehydrogenase

increases expression

Selenium results in increased expression of GAPDH mRNA

NCBI chr12:6,534,517...6,538,371
Ensembl chr12:6,534,512...6,538,374

G

growth arrest specific 8

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GAS8 mRNA
Selenium results in increased expression of GAS8 mRNA

NCBI chr16:90,019,633...90,044,960
Ensembl chr16:90,019,629...90,044,975

G

GATA zinc finger domain containing 2A

increases expression

Selenium results in increased expression of GATAD2A mRNA

NCBI chr19:19,385,843...19,508,932
Ensembl chr19:19,385,826...19,508,932

G

guanylate binding protein 1

decreases expression

Selenium results in decreased expression of GBP1 mRNA

NCBI chr 1:89,052,319...89,065,208
Ensembl chr 1:89,051,882...89,065,360

G

glycine C-acetyltransferase

increases expression

Selenium results in increased expression of GCAT mRNA

NCBI chr22:37,807,934...37,817,183
Ensembl chr22:37,807,905...37,817,176

G

glutamate-cysteine ligase catalytic subunit

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GCLC mRNA

NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970

G

GDP-L-fucose synthase

increases expression

Selenium results in increased expression of GFUS mRNA

NCBI chr 8:143,612,618...143,618,048
Ensembl chr 8:143,612,618...143,618,048

G

geranylgeranyl diphosphate synthase 1

decreases expression

Selenium results in decreased expression of GGPS1 mRNA

NCBI chr 1:235,327,216...235,344,532
Ensembl chr 1:235,327,350...235,344,532

G

gamma-glutamyltransferase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GGT1 mRNA
Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]

PMID:19244175 PMID:24485406

NCBI chr22:24,583,750...24,628,996
Ensembl chr22:24,594,811...24,629,005

G

GIPC PDZ domain containing family member 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of GIPC1 mRNA
Selenium results in increased expression of GIPC1 mRNA

NCBI chr19:14,477,762...14,496,127
Ensembl chr19:14,477,760...14,496,149

G

gap junction protein beta 1

increases expression

Selenium results in increased expression of GJB1 mRNA

NCBI chr X:71,215,239...71,225,516
Ensembl chr X:71,212,811...71,225,516

G

golgi glycoprotein 1

decreases expression
increases expression

Selenium results in decreased expression of GLG1 mRNA
Selenium results in increased expression of GLG1 mRNA

NCBI chr16:74,447,440...74,607,114
Ensembl chr16:74,447,427...74,607,144

G

GLI family zinc finger 2

increases expression

Selenium results in increased expression of GLI2 mRNA

NCBI chr 2:120,735,868...120,992,653
Ensembl chr 2:120,735,623...120,992,653

G

glomulin, FKBP associated protein

decreases expression

Selenium results in decreased expression of GLMN mRNA

NCBI chr 1:92,246,402...92,370,844
Ensembl chr 1:92,246,402...92,298,987

G

glutaredoxin

increases expression
affects expression

Selenium deficiency results in increased expression of GLRX mRNA; Selenium results in increased expression of GLRX mRNA
Selenium affects the expression of GLRX mRNA

PMID:16170372 PMID:19351701

NCBI chr 5:95,813,849...95,822,726
Ensembl chr 5:95,751,319...95,822,726

G

glutaredoxin 2

affects activity
affects expression

Selenium affects the activity of GLRX2 protein
Selenium affects the expression of GLRX2 protein

NCBI chr 1:193,096,465...193,106,114
Ensembl chr 1:193,090,866...193,106,114

G

glutamate dehydrogenase 1

affects expression

Selenium affects the expression of GLUD1 protein

NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843

G

geminin DNA replication inhibitor

decreases expression

Selenium results in decreased expression of GMNN mRNA

NCBI chr 6:24,774,937...24,786,099
Ensembl chr 6:24,774,931...24,786,099

G

GDP-mannose pyrophosphorylase A

increases expression

Selenium results in increased expression of GMPPA mRNA

NCBI chr 2:219,498,891...219,506,989
Ensembl chr 2:219,498,865...219,513,898

G

guanosine monophosphate reductase 2

increases expression

Selenium results in increased expression of GMPR2 mRNA

NCBI chr14:24,232,622...24,239,242
Ensembl chr14:24,232,422...24,239,242

G

G protein subunit alpha i2

increases expression

Selenium results in increased expression of GNAI2 mRNA

NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362

G

GNAS complex locus

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GNAS mRNA
Selenium results in decreased expression of GNAS mRNA

NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192

G

G protein subunit beta 2

increases expression

Selenium results in increased expression of GNB2 mRNA

NCBI chr 7:100,673,740...100,679,169
Ensembl chr 7:100,673,567...100,679,174

G

G protein nucleolar 1 (putative)

increases expression

Selenium results in increased expression of GNL1 mRNA

NCBI chr 6:30,541,381...30,556,489
Ensembl chr 6:30,541,381...30,556,489

G

glycine N-methyltransferase

affects activity

Selenium affects the activity of GNMT protein

NCBI chr 6:42,960,754...42,963,880
Ensembl chr 6:42,960,754...42,963,880

G

gonadotropin releasing hormone 2

increases expression

Selenium results in increased expression of GNRH2 mRNA

NCBI chr20:3,043,622...3,045,747
Ensembl chr20:3,043,622...3,045,747

G

glucosamine (N-acetyl)-6-sulfatase

decreases expression

Selenium results in decreased expression of GNS mRNA

NCBI chr12:64,713,449...64,759,406
Ensembl chr12:64,713,445...64,759,431

G

golgin A3

increases expression
multiple interactions

Selenium results in increased expression of GOLGA3 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of GOLGA3 mRNA

NCBI chr12:132,768,914...132,829,081
Ensembl chr12:132,768,902...132,829,143

G

golgin A8 family member A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of GOLGA8A mRNA

NCBI chr15:34,379,068...34,437,808
Ensembl chr15:34,378,935...34,437,808

G

golgi reassembly stacking protein 1

increases expression

Selenium results in increased expression of GORASP1 mRNA

NCBI chr 3:39,096,599...39,107,627
Ensembl chr 3:39,095,222...39,108,369

G

golgi SNAP receptor complex member 1

decreases expression

Selenium results in decreased expression of GOSR1 mRNA

NCBI chr17:30,477,408...30,527,592
Ensembl chr17:30,477,362...30,527,592

G

glucose-6-phosphate isomerase

increases expression

Selenium results in increased expression of GPI mRNA

NCBI chr19:34,359,718...34,402,413
Ensembl chr19:34,359,480...34,402,413

G

G-patch domain and KOW motifs

increases expression

Selenium results in increased expression of GPKOW mRNA

NCBI chr X:49,113,407...49,123,735
Ensembl chr X:49,113,407...49,123,735

G

G protein-coupled receptor 107

increases expression

Selenium results in increased expression of GPR107 mRNA

NCBI chr 9:130,053,906...130,140,164
Ensembl chr 9:130,053,426...130,140,169

G

G protein-coupled receptor 137

increases expression

Selenium results in increased expression of GPR137 mRNA

NCBI chr11:64,270,531...64,289,500
Ensembl chr11:64,270,062...64,289,494

G

G protein-coupled receptor 137B

decreases expression

Selenium results in decreased expression of GPR137B mRNA

NCBI chr 1:236,142,539...236,208,907
Ensembl chr 1:236,142,505...236,221,865

G

G protein regulated inducer of neurite outgrowth 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of GPRIN2 mRNA

NCBI chr10:46,541,736...46,557,596
Ensembl chr10:46,541,736...46,556,658

G

glutamic--pyruvic transaminase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of GPT protein]; [Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in increased activity of GPT protein]; Selenium inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased activity of GPT protein]

PMID:20688495 PMID:24485406 PMID:30031400 PMID:36464106

NCBI chr 8:144,503,068...144,507,172
Ensembl chr 8:144,502,973...144,507,174

G

glutathione peroxidase 1

affects response to substance
decreases activity
increases activity
increases expression
decreases expression
multiple interactions
affects expression
affects activity

GPX1 gene polymorphism affects the susceptibility to Selenium; GPX1 protein polymorphism affects the susceptibility to Selenium
Selenium deficiency results in decreased activity of GPX1 protein
Selenium results in increased activity of GPX1 protein
Selenium results in increased expression of GPX1 mRNA; Selenium results in increased expression of GPX1 protein
Selenium deficiency results in decreased expression of GPX1 mRNA; Selenium deficiency results in decreased expression of GPX1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of GPX1 mRNA; Selenium inhibits the reaction [2-iodohexadecanal results in decreased expression of GPX1 mRNA]; Selenium inhibits the reaction [arsenite results in decreased expression of GPX1 protein]; Selenium inhibits the reaction [Cisplatin results in decreased expression of GPX1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of GPX1 mRNA]; Selenium results in increased expression of and results in decreased degradation of GPX1 mRNA
Selenium affects the expression of GPX1 mRNA
Selenium affects the activity of GPX1 protein
Selenium deficiency inhibits the reaction [IL4 protein results in increased expression of GPX1 protein]; Selenium deficiency inhibits the reaction [Lipopolysaccharides results in increased expression of GPX1 protein]; Selenium deficiency results in decreased expression of and results in decreased activity of GPX1 protein
Selenium affects the expression of GPX1 mRNA; Selenium affects the expression of GPX1 protein

PMID:10874123 PMID:10949970 PMID:11294903 PMID:11444866 PMID:11463357 More...

NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605

G

glutathione peroxidase 2

decreases activity
decreases expression

Selenium deficiency results in decreased activity of GPX2 protein
Selenium deficiency results in decreased expression of GPX2 mRNA

NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746

G

glutathione peroxidase 3

increases expression
affects activity
increases activity
affects expression

Selenium results in increased expression of GPX3 mRNA
Selenium affects the activity of GPX3 protein
Selenium results in increased activity of GPX3 protein
Selenium affects the expression of GPX3 mRNA

PMID:15894816 PMID:19022953 PMID:19106321 PMID:19244175 PMID:19351701

NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988

G

glutathione peroxidase 4

increases activity
decreases expression
multiple interactions
increases expression
decreases activity
affects activity
decreases abundance

Selenium analog results in increased activity of GPX4 protein
Selenium deficiency results in decreased expression of GPX4 protein
Selenomethionine inhibits the reaction [Selenium deficiency results in decreased expression of GPX4 protein]; Sodium Selenite inhibits the reaction [Selenium deficiency results in decreased expression of GPX4 protein]
[2-hydroxy-4-methylselenobutanoic acid results in increased abundance of Selenium] which results in increased expression of GPX4 protein
Selenium deficiency results in decreased expression of GPX4 mRNA
Selenium results in increased expression of GPX4 mRNA
Selenium deficiency results in decreased activity of GPX4 protein
Selenium affects the activity of GPX4 protein
Selenium results in increased activity of GPX4 protein
GPX4 gene mutant form results in decreased abundance of Selenium
Selenium results in increased expression of and results in increased activity of GPX4 protein
Selenium results in increased expression of GPX4 mRNA; Selenium results in increased expression of GPX4 protein

PMID:11673642 PMID:12031252 PMID:15670848 PMID:15792362 PMID:16246897 More...

NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791

G

glutathione peroxidase 5

affects expression

Selenium affects the expression of GPX5

NCBI chr 6:28,525,881...28,534,955
Ensembl chr 6:28,525,881...28,534,955

G

glutamate ionotropic receptor AMPA type subunit 2

decreases expression

Selenium results in decreased expression of GRIA2 mRNA

NCBI chr 4:157,220,120...157,366,075
Ensembl chr 4:157,204,182...157,387,146

G

glutamate ionotropic receptor NMDA type subunit associated protein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GRINA mRNA
Selenium results in increased expression of GRINA mRNA

NCBI chr 8:143,990,056...143,993,415
Ensembl chr 8:143,990,056...143,993,415

G

G protein-coupled receptor kinase 6

increases expression

Selenium results in increased expression of GRK6 mRNA

NCBI chr 5:177,425,523...177,442,891
Ensembl chr 5:177,403,204...177,442,901

G

granulin precursor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of GRN mRNA
Selenium results in increased expression of GRN mRNA

NCBI chr17:44,345,302...44,353,106
Ensembl chr17:44,345,246...44,353,106

G

gasdermin E

decreases expression

Selenium results in decreased expression of GSDME mRNA

NCBI chr 7:24,698,355...24,795,539
Ensembl chr 7:24,698,355...24,757,940

G

glycogen synthase kinase 3 alpha

increases expression

Selenium results in increased expression of GSK3A mRNA

NCBI chr19:42,230,190...42,242,602
Ensembl chr19:42,226,225...42,242,625

G

glycogen synthase kinase 3 beta

multiple interactions
decreases phosphorylation
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of GSK3B mRNA; Selenium inhibits the reaction [Doxorubicin results in increased phosphorylation of GSK3B protein]
Selenium results in decreased phosphorylation of GSK3B protein
Selenium results in decreased expression of GSK3B mRNA

PMID:17339365 PMID:19244175

NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994

G

gelsolin

increases expression

Selenium results in increased expression of GSN mRNA

NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843

G

glutathione-disulfide reductase

multiple interactions

Selenium inhibits the reaction [cyfluthrin results in decreased activity of GSR protein]

NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846

G

glutathione S-transferase alpha 5

increases expression

Selenium deficiency results in increased expression of GSTA5 mRNA; Selenium deficiency results in increased expression of GSTA5 protein

NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843

G

glutathione S-transferase pi 1

multiple interactions
affects expression
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GSTP1 mRNA
Selenium affects the expression of GSTP1 protein
Selenium results in increased expression of GSTP1 mRNA

PMID:7532609 PMID:19244175

NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656

G

glutathione S-transferase theta 1

increases expression

Selenium deficiency results in increased expression of GSTT1

G

general transcription factor IIF subunit 1

increases expression

Selenium results in increased expression of GTF2F1 mRNA

NCBI chr19:6,379,572...6,393,164
Ensembl chr19:6,379,572...6,393,981

G

general transcription factor IIH subunit 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of GTF2H2 mRNA
Selenium results in decreased expression of GTF2H2 mRNA

NCBI chr 5:71,035,347...71,067,676
Ensembl chr 5:71,035,016...71,067,689

G

general transcription factor IIIC subunit 1

increases expression

Selenium results in increased expression of GTF3C1 mRNA

NCBI chr16:27,460,613...27,549,913
Ensembl chr16:27,459,555...27,549,913

G

GTP binding protein 8 (putative)

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GTPBP8 mRNA
Selenium results in decreased expression of GTPBP8 mRNA

NCBI chr 3:112,990,984...113,001,969
Ensembl chr 3:112,990,984...113,015,060

G

GULP PTB domain containing engulfment adaptor 1

decreases expression

Selenium results in decreased expression of GULP1 mRNA

NCBI chr 2:188,291,874...188,595,926
Ensembl chr 2:188,291,669...188,595,931

G

GUSB pseudogene 15

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of GUSBP15 mRNA
Selenium results in decreased expression of GUSBP15 mRNA

NCBI chr 5:70,481,043...70,585,722
Ensembl chr 5:70,516,387...70,555,266

G

H2A.X variant histone

increases expression

Selenium results in increased expression of H2AX mRNA

NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465

G

H3.3 histone A

decreases expression

Selenium results in decreased expression of H3-3A mRNA

NCBI chr 1:226,061,831...226,072,019
Ensembl chr 1:226,061,851...226,072,019

G

H4 clustered histone 6

decreases expression

Selenium results in decreased expression of H4C6 mRNA

NCBI chr 6:26,240,393...26,240,793
Ensembl chr 6:26,240,393...26,240,793

G

hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of H6PD mRNA
Selenium results in increased expression of H6PD mRNA

NCBI chr 1:9,234,774...9,271,337
Ensembl chr 1:9,234,774...9,271,337

G

hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha

decreases expression

Selenium results in decreased expression of HADHA mRNA

NCBI chr 2:26,190,635...26,244,632
Ensembl chr 2:26,190,635...26,244,672

G

hydroxyacylglutathione hydrolase

increases expression

Selenium results in increased expression of HAGH mRNA

NCBI chr16:1,807,629...1,827,194
Ensembl chr16:1,795,620...1,827,157

G

histidyl-tRNA synthetase 1

increases expression

Selenium results in increased expression of HARS1 mRNA

NCBI chr 5:140,673,905...140,691,370
Ensembl chr 5:140,673,035...140,691,537

G

HAUS augmin like complex subunit 3

decreases expression
multiple interactions

Selenium results in decreased expression of HAUS3 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of HAUS3 mRNA

NCBI chr 4:2,228,349...2,242,121
Ensembl chr 4:2,227,464...2,242,133

G

HAUS augmin like complex subunit 4

increases expression

Selenium results in increased expression of HAUS4 mRNA

NCBI chr14:22,946,228...22,957,090
Ensembl chr14:22,946,228...22,957,161

G

hemoglobin subunit alpha 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of HBA2 mRNA

NCBI chr16:172,876...173,710
Ensembl chr16:172,876...173,710

G

heparin binding growth factor

increases expression

Selenium results in increased expression of HDGF mRNA

NCBI chr 1:156,742,107...156,767,366
Ensembl chr 1:156,742,109...156,766,925

G

high density lipoprotein binding protein

increases expression

Selenium results in increased expression of HDLBP mRNA

NCBI chr 2:241,227,291...241,315,672
Ensembl chr 2:241,227,264...241,317,061

G

hephaestin

decreases expression

Selenium results in decreased expression of HEPH mRNA

NCBI chr X:66,162,671...66,268,863
Ensembl chr X:66,162,671...66,268,867

G

HERC2 pseudogene 2

decreases expression

Selenium results in decreased expression of HERC2P2 mRNA

NCBI chr15:22,494,837...22,590,831
Ensembl chr15:22,495,570...22,579,813

G

hes family bHLH transcription factor 1

decreases expression
multiple interactions

Selenium results in decreased expression of HES1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of HES1 mRNA

NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732

G

hepatocyte growth factor-regulated tyrosine kinase substrate

increases expression

Selenium results in increased expression of HGS mRNA

NCBI chr17:81,684,011...81,702,121
Ensembl chr17:81,683,326...81,703,138

G

hedgehog interacting protein

increases expression

Selenium results in increased expression of HHIP mRNA

NCBI chr 4:144,646,156...144,745,271
Ensembl chr 4:144,646,156...144,745,271

G

huntingtin interacting protein 1 related

increases expression

Selenium results in increased expression of HIP1R mRNA

NCBI chr12:122,834,748...122,862,961
Ensembl chr12:122,834,453...122,862,961

G

homeodomain interacting protein kinase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HIPK2 mRNA
Selenium results in decreased expression of HIPK2 mRNA

NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998

G

HIRA interacting protein 3

increases expression

Selenium results in increased expression of HIRIP3 mRNA

NCBI chr16:29,992,321...29,996,096
Ensembl chr16:29,992,330...29,996,074

G

major histocompatibility complex, class I, B

increases expression

Selenium results in increased expression of HLA-B mRNA

NCBI chr 6:31,353,875...31,357,179
Ensembl chr 6:31,353,872...31,367,067

G

major histocompatibility complex, class I, C

increases expression

Selenium results in increased expression of HLA-C mRNA

NCBI chr 6:31,268,749...31,272,092
Ensembl chr 6:31,268,749...31,272,130

G

major histocompatibility complex, class II, DP alpha 1

increases expression

Selenium results in increased expression of HLA-DPA1 mRNA

NCBI chr 6:33,064,569...33,080,748
Ensembl chr 6:33,064,569...33,080,775

G

major histocompatibility complex, class II, DQ beta 1

increases expression

Selenium results in increased expression of HLA-DQB1 mRNA

NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383

G

major histocompatibility complex, class II, DR alpha

increases expression

Selenium results in increased expression of HLA-DRA mRNA

NCBI chr 6:32,439,887...32,445,046
Ensembl chr 6:32,439,878...32,445,046

G

major histocompatibility complex, class II, DR beta 3

increases expression

Selenium results in increased expression of HLA-DRB3 mRNA

G

major histocompatibility complex, class I, E

increases expression

Selenium results in increased expression of HLA-E mRNA

NCBI chr 6:30,489,509...30,494,194
Ensembl chr 6:30,489,509...30,494,194

G

major histocompatibility complex, class I, F

decreases expression
increases expression

Selenium results in decreased expression of HLA-F mRNA
Selenium results in increased expression of HLA-F mRNA

NCBI chr 6:29,723,434...29,738,532
Ensembl chr 6:29,722,775...29,738,528

G

major histocompatibility complex, class I, G

increases expression

Selenium results in increased expression of HLA-G mRNA

NCBI chr 6:29,826,474...29,831,021
Ensembl chr 6:29,826,967...29,831,125

G

HLF transcription factor, PAR bZIP family member

decreases expression

Selenium results in decreased expression of HLF mRNA

NCBI chr17:55,264,960...55,325,187
Ensembl chr17:55,264,960...55,325,187

G

hydroxymethylbilane synthase

increases expression

Selenium results in increased expression of HMBS mRNA

NCBI chr11:119,084,881...119,093,549
Ensembl chr11:119,084,866...119,093,834

G

high mobility group box 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of HMGB1 mRNA

NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of HMGCR mRNA]; Selenium promotes the reaction [Cholesterol results in decreased expression of HMGCR mRNA]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of HMGCR mRNA]

PMID:16581047 PMID:30031400 PMID:36464106

NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001

G

HMG-box containing 3

increases expression

Selenium results in increased expression of HMGXB3 mRNA

NCBI chr 5:150,000,739...150,053,128
Ensembl chr 5:150,000,046...150,053,142

G

HMG-box containing 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HMGXB4 mRNA
Selenium results in decreased expression of HMGXB4 mRNA

NCBI chr22:35,241,536...35,295,807
Ensembl chr22:35,257,452...35,295,807

G

heme oxygenase 1

multiple interactions
increases expression
affects expression
affects activity

[Arsenic co-treated with Selenium] results in increased expression of HMOX1 mRNA; [Arsenic co-treated with Selenium] results in increased expression of HMOX1 protein; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] affects the expression of HMOX1 mRNA; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of HMOX1 mRNA
Selenium deficiency results in increased expression of HMOX1 mRNA
Phenobarbital promotes the reaction [Selenium deficiency results in increased expression of and results in increased activity of HMOX1 protein]; Phenobarbital promotes the reaction [Selenium deficiency results in increased expression of HMOX1 mRNA]; Selenium deficiency results in increased expression of and results in increased activity of HMOX1 protein; Selenium inhibits the reaction [Cisplatin results in increased expression of HMOX1 protein]
Selenium affects the expression of HMOX1 protein
Selenium affects the activity of HMOX1 protein
NFE2L2 protein affects the reaction [Selenium affects the activity of HMOX1 protein]
Selenium results in increased expression of HMOX1 mRNA; Selenium results in increased expression of HMOX1 protein

PMID:12751798 PMID:16837816 PMID:18279678 PMID:20478284 PMID:21481475

NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214

G

H6 family homeobox 1

increases expression

Selenium results in increased expression of HMX1 mRNA

NCBI chr 4:8,846,076...8,871,839
Ensembl chr 4:8,846,076...8,871,839

G

HNF1 homeobox B

increases expression

Selenium results in increased expression of HNF1B mRNA

NCBI chr17:37,686,431...37,745,059
Ensembl chr17:37,686,431...37,745,059

G

histamine N-methyltransferase

decreases expression
multiple interactions

Selenium results in decreased expression of HNMT mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HNMT mRNA

NCBI chr 2:137,964,473...138,016,364
Ensembl chr 2:137,964,020...138,016,364

G

heterogeneous nuclear ribonucleoprotein D

increases expression

Selenium results in increased expression of HNRNPD mRNA

NCBI chr 4:82,352,498...82,373,991
Ensembl chr 4:82,352,498...82,374,503

G

heterogeneous nuclear ribonucleoprotein M

increases expression

Selenium results in increased expression of HNRNPM mRNA

NCBI chr19:8,444,975...8,489,114
Ensembl chr19:8,444,767...8,489,114

G

homer scaffold protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of HOMER1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HOMER1 mRNA

NCBI chr 5:79,372,636...79,514,134
Ensembl chr 5:79,372,636...79,514,134

G

hook microtubule tethering protein 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HOOK1 mRNA
Selenium results in decreased expression of HOOK1 mRNA

NCBI chr 1:59,814,949...59,876,322
Ensembl chr 1:59,814,786...59,876,322

G

hippocalcin like 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HPCAL1 mRNA
Selenium results in increased expression of HPCAL1 mRNA

NCBI chr 2:10,302,904...10,427,604
Ensembl chr 2:10,302,889...10,427,617

G

hematopoietic prostaglandin D synthase

multiple interactions

[Selenium deficiency co-treated with 4-(benzo(b)thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one co-treated with Lipopolysaccharides] results in increased expression of HPGDS mRNA; [Selenium deficiency co-treated with 4-(benzo(b)thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one co-treated with Lipopolysaccharides] results in increased expression of HPGDS protein; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in increased expression of HPGDS mRNA; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in increased expression of HPGDS protein; [Selenium deficiency co-treated with rosiglitazone] results in increased expression of HPGDS protein

NCBI chr 4:94,298,535...94,342,836
Ensembl chr 4:94,298,535...94,342,876

G

hepsin

increases expression

Selenium results in increased expression of HPN mRNA

NCBI chr19:35,040,506...35,066,573
Ensembl chr19:35,040,506...35,066,573

G

HRas proto-oncogene, GTPase

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of HRAS mRNA
Selenium results in increased expression of HRAS mRNA

NCBI chr11:532,242...535,576
Ensembl chr11:532,242...537,321

G

heparan sulfate-glucosamine 3-sulfotransferase 3A1

decreases expression

Selenium results in decreased expression of HS3ST3A1 mRNA

NCBI chr17:13,494,032...13,601,929
Ensembl chr17:13,494,032...13,601,929

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of HSD11B2 mRNA; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSD11B2 protein]; [Sodium Selenite results in increased abundance of Selenium] which results in increased expression of HSD11B2 protein

PMID:11444866 PMID:35384129

NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553

G

hydroxysteroid 17-beta dehydrogenase 11

increases expression

Selenium deficiency results in increased expression of HSD17B11 mRNA; Selenium results in increased expression of HSD17B11 mRNA

NCBI chr 4:87,336,515...87,391,188
Ensembl chr 4:87,336,515...87,391,188

G

hydroxysteroid 17-beta dehydrogenase 8

increases expression

Selenium results in increased expression of HSD17B8 mRNA

NCBI chr 6:33,204,655...33,206,831
Ensembl chr 6:33,204,655...33,206,831

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1

increases expression

Selenium deficiency results in increased expression of HSD3B2 mRNA; Selenium results in increased expression of HSD3B2 mRNA

NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054

G

heat shock protein 90 alpha family class A member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HSP90AA1 mRNA
Selenium results in decreased expression of HSP90AA1 mRNA

NCBI chr14:102,080,742...102,139,749
Ensembl chr14:102,080,742...102,139,699

G

heat shock protein 90 alpha family class B member 1

increases expression

Selenium results in increased expression of HSP90AB1 mRNA

NCBI chr 6:44,246,194...44,253,883
Ensembl chr 6:44,246,166...44,253,888

G

heat shock protein 90 beta family member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of HSP90B1 mRNA
Selenium results in decreased expression of HSP90B1 mRNA

NCBI chr12:103,930,410...103,947,926
Ensembl chr12:103,930,107...103,953,931

G

heat shock protein family A (Hsp70) member 1A

increases expression
multiple interactions

Selenium results in increased expression of HSPA1A mRNA; Selenium results in increased expression of HSPA1A protein
[Selenium co-treated with Fluorides] results in increased expression of HSPA1A mRNA; Fluorides promotes the reaction [Selenium results in increased expression of HSPA1A protein]

PMID:19244175 PMID:19652462

NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946

G

heat shock protein family A (Hsp70) member 4

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of HSPA4 mRNA

NCBI chr 5:133,052,013...133,106,449
Ensembl chr 5:133,052,013...133,106,449

G

heat shock protein family A (Hsp70) member 9

decreases expression
multiple interactions

Selenium results in decreased expression of HSPA9 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of HSPA9 mRNA

NCBI chr 5:138,553,756...138,575,401
Ensembl chr 5:138,553,756...138,575,675

G

heat shock protein family B (small) member 1

increases expression

Selenium results in increased expression of HSPB1 mRNA

NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295

G

heat shock protein family B (small) member 2

decreases expression

Selenium results in decreased expression of HSPB2 mRNA

NCBI chr11:111,912,734...111,914,093
Ensembl chr11:111,912,734...111,914,093

G

HSPB1 associated protein 1

decreases expression

Selenium results in decreased expression of HSPBAP1 mRNA

NCBI chr 3:122,739,999...122,793,831
Ensembl chr 3:122,739,999...122,793,831

G

5-hydroxytryptamine receptor 4

increases expression

Selenium results in increased expression of HTR4 mRNA

NCBI chr 5:148,451,032...148,654,527
Ensembl chr 5:148,446,042...148,677,235

G

isoleucyl-tRNA synthetase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of IARS1 mRNA
Selenium results in decreased expression of IARS1 mRNA

NCBI chr 9:92,210,207...92,293,697
Ensembl chr 9:92,210,207...92,293,854

G

islet cell autoantigen 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ICA1 mRNA
Selenium results in increased expression of ICA1 mRNA

NCBI chr 7:8,113,184...8,262,555
Ensembl chr 7:8,113,184...8,262,687

G

inhibitor of DNA binding 1

increases expression

Selenium results in increased expression of ID1 mRNA

NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515

G

inhibitor of DNA binding 2

decreases expression

Selenium results in decreased expression of ID2 mRNA

NCBI chr 2:8,682,056...8,684,461
Ensembl chr 2:8,678,845...8,684,461

G

inhibitor of DNA binding 2B (pseudogene)

decreases expression

Selenium results in decreased expression of ID2B mRNA

NCBI chr 3:62,123,426...62,124,718

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta

increases expression

Selenium results in increased expression of IDH3B mRNA

NCBI chr20:2,658,395...2,664,216
Ensembl chr20:2,658,395...2,664,219

G

isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of IDH3G mRNA
Selenium results in increased expression of IDH3G mRNA

NCBI chr X:153,785,768...153,794,375
Ensembl chr X:153,785,766...153,794,512

G

alpha-L-iduronidase

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of IDUA mRNA
Selenium results in increased expression of IDUA mRNA

NCBI chr 4:986,997...1,008,351
Ensembl chr 4:986,997...1,004,564

G

immediate early response 3

increases expression

Selenium results in increased expression of IER3 mRNA

NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548

G

interferon induced protein 35

increases expression

Selenium results in increased expression of IFI35 mRNA

NCBI chr17:43,006,784...43,014,456
Ensembl chr17:43,006,740...43,014,456

G

interferon alpha inducible protein 6

increases expression

Selenium results in increased expression of IFI6 mRNA

NCBI chr 1:27,666,064...27,672,192
Ensembl chr 1:27,666,064...27,672,212

G

interferon induced transmembrane protein 1

increases expression

Selenium results in increased expression of IFITM1 mRNA

NCBI chr11:314,040...315,272
Ensembl chr11:310,041...315,272

G

interferon induced transmembrane protein 2

increases expression

Selenium results in increased expression of IFITM2 mRNA

NCBI chr11:307,816...309,395
Ensembl chr11:303,655...309,397

G

interferon induced transmembrane protein 3

increases expression

Selenium results in increased expression of IFITM3 mRNA

NCBI chr11:319,676...320,860
Ensembl chr11:319,676...329,475

G

interferon alpha 1

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] affects the expression of IFNA1 mRNA

NCBI chr 9:21,440,439...21,441,316
Ensembl chr 9:21,440,439...21,441,316

G

interferon alpha 10

decreases expression

Selenium results in decreased expression of IFNA10 mRNA

NCBI chr 9:21,206,181...21,207,143
Ensembl chr 9:21,206,181...21,207,143

G

interferon gamma

decreases expression

Selenium results in decreased expression of IFNG protein

NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740

G

interferon related developmental regulator 2

increases expression

Selenium results in increased expression of IFRD2 mRNA

NCBI chr 3:50,287,732...50,292,429
Ensembl chr 3:50,287,732...50,292,918

G

intraflagellar transport 74

decreases expression
multiple interactions

Selenium results in decreased expression of IFT74 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of IFT74 mRNA

NCBI chr 9:26,947,110...27,066,134
Ensembl chr 9:26,947,039...27,066,134

G

intraflagellar transport 81

decreases expression

Selenium results in decreased expression of IFT81 mRNA

NCBI chr12:110,124,357...110,218,793
Ensembl chr12:110,124,335...110,218,793

G

insulin like growth factor 2 receptor

decreases expression

Selenium results in decreased expression of IGF2R mRNA

NCBI chr 6:159,969,082...160,111,504
Ensembl chr 6:159,969,082...160,113,507

G

insulin like growth factor binding protein 2

increases expression

Selenium results in increased expression of IGFBP2 mRNA

NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436

G

insulin like growth factor binding protein 3

increases expression

Selenium results in increased expression of IGFBP3 mRNA; Selenium results in increased expression of IGFBP3 protein

PMID:15318950 PMID:18997278

NCBI chr 7:45,912,245...45,921,272
Ensembl chr 7:45,912,245...45,921,874

G

insulin like growth factor binding protein 4

increases expression

Selenium results in increased expression of IGFBP4 mRNA

NCBI chr17:40,443,450...40,457,725
Ensembl chr17:40,443,450...40,457,725

G

insulin like growth factor binding protein 6

increases expression

Selenium results in increased expression of IGFBP6 mRNA

NCBI chr12:53,097,667...53,102,340
Ensembl chr12:53,097,436...53,102,345

G

immunoglobulin heavy constant mu

increases expression

Selenium results in increased expression of IGHM mRNA

NCBI chr14:105,851,966...105,856,217
Ensembl chr14:105,851,705...105,856,218

G

IK cytokine

increases expression

Selenium results in increased expression of IK mRNA

NCBI chr 5:140,647,829...140,662,480
Ensembl chr 5:140,647,058...140,662,480

G

inhibitor of nuclear factor kappa B kinase subunit beta

multiple interactions

Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of IKBKB protein]
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IKBKB mRNA

PMID:17439952 PMID:21481475

NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460

G

interleukin 10

multiple interactions

[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in decreased expression of IL10 protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL10 protein]
[Drugs, Chinese Herbal co-treated with Selenium] results in increased expression of IL10 mRNA
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL10 mRNA; [Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL10 mRNA

PMID:15862027 PMID:21481475 PMID:24626144 PMID:26089086

NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541

G

interleukin 17 receptor C

increases expression

Selenium results in increased expression of IL17RC mRNA

NCBI chr 3:9,917,098...9,933,621
Ensembl chr 3:9,917,074...9,933,630

G

interleukin 1 beta

multiple interactions
increases expression

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL1B mRNA; Selenium affects the reaction [IL1B protein results in increased abundance of Hydrogen Peroxide]; Selenium inhibits the reaction [IL1B protein results in increased abundance of Hydrogen Peroxide]; Selenium promotes the reaction [T-2 Toxin results in increased expression of IL1B protein]
Selenium deficiency results in increased expression of IL1B mRNA
[Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of IL1B mRNA; Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of IL1B mRNA]
Selenium results in increased expression of IL1B mRNA

PMID:10802230 PMID:17293063 PMID:17630198 PMID:18196609 PMID:21481475 More...

NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816

G

interleukin 1 receptor type 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1R2 mRNA

NCBI chr 2:101,991,960...102,028,544
Ensembl chr 2:101,991,960...102,028,544

G

interleukin 1 receptor accessory protein like 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RAPL2 mRNA

NCBI chr X:104,566,199...105,767,829
Ensembl chr X:104,566,199...105,767,829

G

interleukin 1 receptor like 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RL2 mRNA

NCBI chr 2:102,186,973...102,243,086
Ensembl chr 2:102,187,006...102,240,002

G

interleukin 1 receptor antagonist

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of IL1RN mRNA

NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016

G

interleukin 2

affects expression

Selenium affects the expression of IL2 protein

NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725

G

interleukin 37

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL37 mRNA

NCBI chr 2:112,911,165...112,918,882
Ensembl chr 2:112,911,165...112,918,882

G

interleukin 4

decreases expression
multiple interactions

Selenium results in decreased expression of IL4 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; 2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA]; 4-benzhydryloxy-1-(3-(1H-tetrazol-5-yl-)-propyl)piperidine inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; [Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein; [Selenium co-treated with IL4 protein] results in increased expression of ARG1 mRNA; [Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of IL1B mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of TNF mRNA; leflunomide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; rosiglitazone promotes the reaction [[Selenium co-treated with IL4 protein] results in increased activity of ARG1 protein]; Selenium deficiency inhibits the reaction [IL4 protein results in increased expression of GPX1 protein]
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] results in increased expression of IL4 protein

PMID:14624943 PMID:15862027 PMID:21775527

NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678

G

interleukin 4 receptor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IL4R mRNA
Selenium results in increased expression of IL4R mRNA

NCBI chr16:27,313,756...27,364,778
Ensembl chr16:27,313,668...27,364,778

G

interleukin 6

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IL6 mRNA
Selenium affects the reaction [Mercuric Chloride results in decreased expression of IL6 protein]

PMID:21481475 PMID:26089086

NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002

G

interleukin 6 cytokine family signal transducer

decreases expression

Selenium results in decreased expression of IL6ST mRNA

NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022

G

interleukin enhancer binding factor 3

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of ILF3 mRNA

NCBI chr19:10,654,346...10,692,400
Ensembl chr19:10,654,304...10,692,400

G

integrin linked kinase

increases expression

Selenium results in increased expression of ILK mRNA

NCBI chr11:6,603,774...6,610,870
Ensembl chr11:6,603,708...6,610,874

G

inflammation and lipid regulator with UBA-like and NBR1-like domains

increases expression

Selenium results in increased expression of ILRUN mRNA

NCBI chr 6:34,587,288...34,696,767
Ensembl chr 6:34,587,288...34,696,859

G

inositol polyphosphate-5-phosphatase K

increases expression

Selenium results in increased expression of INPP5K mRNA

NCBI chr17:1,494,577...1,516,612
Ensembl chr17:1,494,577...1,516,742

G

insulin

multiple interactions

[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in decreased secretion of INS protein]; Selenium analog inhibits the reaction [Diazinon results in decreased secretion of INS protein alternative form]; Selenium analog inhibits the reaction [Diazinon results in decreased secretion of INS protein]

NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221

G

INS-IGF2 readthrough

multiple interactions

[Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 mRNA; [Selenium co-treated with Vitamin E co-treated with Vanadium co-treated with Chromium] results in increased expression of INS1 protein

NCBI chr11:2,129,117...2,161,209
Ensembl chr11:2,132,538...2,161,209

G

integrator complex subunit 1

increases expression

Selenium results in increased expression of INTS1 mRNA

NCBI chr 7:1,470,277...1,504,389
Ensembl chr 7:1,470,277...1,504,389

G

integrator complex subunit 15

increases expression

Selenium results in increased expression of INTS15 mRNA

NCBI chr 7:6,590,021...6,608,726
Ensembl chr 7:6,590,021...6,608,726

G

integrator complex subunit 3

increases expression

Selenium results in increased expression of INTS3 mRNA

NCBI chr 1:153,728,050...153,774,808
Ensembl chr 1:153,728,050...153,774,808

G

integrator complex subunit 6

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of INTS6 mRNA
Selenium results in decreased expression of INTS6 mRNA

NCBI chr13:51,334,405...51,453,036
Ensembl chr13:51,354,077...51,454,264

G

IQ motif containing B1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IQCB1 mRNA
Selenium results in decreased expression of IQCB1 mRNA

NCBI chr 3:121,769,761...121,835,060
Ensembl chr 3:121,769,761...121,835,079

G

IQ motif containing K

decreases expression
multiple interactions

Selenium results in decreased expression of IQCK mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of IQCK mRNA

NCBI chr16:19,718,271...19,858,467
Ensembl chr16:19,716,456...19,858,467

G

interleukin 1 receptor associated kinase 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of IRAK2 mRNA

NCBI chr 3:10,164,919...10,243,745
Ensembl chr 3:10,164,919...10,243,745

G

interferon regulatory factor 3

increases expression

Selenium results in increased expression of IRF3 mRNA

NCBI chr19:49,659,572...49,665,857
Ensembl chr19:49,659,569...49,665,875

G

interferon regulatory factor 9

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of IRF9 mRNA
Selenium results in increased expression of IRF9 mRNA

NCBI chr14:24,161,265...24,166,565
Ensembl chr14:24,161,234...24,168,043

G

inositol-3-phosphate synthase 1

increases expression

Selenium results in increased expression of ISYNA1 mRNA

NCBI chr19:18,434,388...18,438,133
Ensembl chr19:18,434,388...18,438,167

G

integrin subunit alpha 3

increases expression
multiple interactions

Selenium results in increased expression of ITGA3 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ITGA3 mRNA

NCBI chr17:50,056,110...50,090,481
Ensembl chr17:50,055,968...50,090,481

G

integrin subunit alpha E

decreases expression

Selenium results in decreased expression of ITGAE mRNA

NCBI chr17:3,714,628...3,801,188
Ensembl chr17:3,714,628...3,801,188

G

integral membrane protein 2C

increases expression

Selenium results in increased expression of ITM2C mRNA

NCBI chr 2:230,864,185...230,879,254
Ensembl chr 2:230,864,639...230,879,248

G

Jun proto-oncogene, AP-1 transcription factor subunit

multiple interactions
increases expression

[Selenium co-treated with Iodine] results in increased expression of JUN mRNA; [Selenium co-treated with Iodine] results in increased expression of JUN protein
Selenium results in increased expression of JUN mRNA; Selenium results in increased expression of JUN protein

PMID:12475444 PMID:12666833

NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048

G

KAT8 regulatory NSL complex subunit 2

decreases expression

Selenium results in decreased expression of KANSL2 mRNA

NCBI chr12:48,653,211...48,682,238
Ensembl chr12:48,653,211...48,682,238

G

lysine acetyltransferase 5

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of KAT5 mRNA

NCBI chr11:65,712,018...65,719,604
Ensembl chr11:65,711,996...65,719,604

G

potassium inwardly rectifying channel subfamily J member 15

increases expression

Selenium results in increased expression of KCNJ15 mRNA

NCBI chr21:38,229,926...38,307,357
Ensembl chr21:38,155,549...38,307,357

G

potassium channel tetramerization domain containing 17

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of KCTD17 mRNA
Selenium results in increased expression of KCTD17 mRNA

NCBI chr22:37,051,742...37,063,390
Ensembl chr22:37,051,739...37,063,390

G

lysine demethylase 6B

increases expression

Selenium results in increased expression of KDM6B mRNA

NCBI chr17:7,834,217...7,854,796
Ensembl chr17:7,834,217...7,854,796

G

kelch like ECH associated protein 1

increases expression

Selenium results in increased expression of KEAP1 mRNA

NCBI chr19:10,486,125...10,503,356
Ensembl chr19:10,486,125...10,503,558

G

KIAA0040

increases expression

Selenium results in increased expression of KIAA0040 mRNA

NCBI chr 1:175,156,986...175,192,987
Ensembl chr 1:175,156,986...175,192,999

G

kinesin family member 1C

increases expression

Selenium results in increased expression of KIF1C mRNA

NCBI chr17:4,997,950...5,028,401
Ensembl chr17:4,997,950...5,028,401

G

kinesin family member 5C

decreases expression

Selenium results in decreased expression of KIF5C mRNA

NCBI chr 2:148,875,227...149,026,759
Ensembl chr 2:148,875,227...149,026,759

G

klotho

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KL mRNA

NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143

G

KLF transcription factor 12

increases expression

Selenium results in increased expression of KLF12 mRNA

NCBI chr13:73,686,089...74,306,045
Ensembl chr13:73,686,089...74,134,404

G

KLF transcription factor 6

increases expression

Selenium results in increased expression of KLF6 mRNA

NCBI chr10:3,775,996...3,785,209
Ensembl chr10:3,775,996...3,785,281

G

KLF transcription factor 9

decreases expression

Selenium results in decreased expression of KLF9 mRNA

NCBI chr 9:70,384,604...70,414,657
Ensembl chr 9:70,384,604...70,414,657

G

kelch domain containing 10

decreases expression

Selenium results in decreased expression of KLHDC10 mRNA

NCBI chr 7:130,070,534...130,135,705
Ensembl chr 7:130,070,534...130,135,705

G

kelch like family member 20

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KLHL20 mRNA
Selenium results in decreased expression of KLHL20 mRNA

NCBI chr 1:173,714,981...173,786,692
Ensembl chr 1:173,714,941...173,786,692

G

kelch like family member 24

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KLHL24 mRNA

NCBI chr 3:183,635,623...183,684,519
Ensembl chr 3:183,635,610...183,684,519

G

kelch like family member 9

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of KLHL9 mRNA

NCBI chr 9:21,329,665...21,335,404
Ensembl chr 9:21,329,665...21,335,404

G

kallikrein related peptidase 3

decreases expression

Selenium results in decreased expression of KLK3 mRNA; Selenium results in decreased expression of KLK3 protein

NCBI chr19:50,854,915...50,860,764
Ensembl chr19:50,854,915...50,860,764

G

lysine methyltransferase 2B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of KMT2B mRNA
Selenium results in increased expression of KMT2B mRNA

NCBI chr19:35,718,003...35,738,878
Ensembl chr19:35,717,973...35,738,880

G

karyopherin subunit alpha 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KPNA1 mRNA
Selenium results in decreased expression of KPNA1 mRNA

NCBI chr 3:122,421,902...122,514,939
Ensembl chr 3:122,421,902...122,514,945

G

karyopherin subunit alpha 6

increases expression

Selenium results in increased expression of KPNA6 mRNA

NCBI chr 1:32,108,056...32,176,563
Ensembl chr 1:32,108,056...32,176,563

G

karyopherin subunit beta 1

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KPNB1 mRNA
Selenium results in increased expression of KPNB1 mRNA
Selenium results in decreased expression of KPNB1 mRNA

NCBI chr17:47,649,919...47,685,505
Ensembl chr17:47,649,476...47,685,505

G

KRR1 small subunit processome component homolog

decreases expression

Selenium results in decreased expression of KRR1 mRNA

NCBI chr12:75,490,863...75,511,609
Ensembl chr12:75,490,863...75,511,636

G

keratin 17

increases expression

Selenium results in increased expression of KRT17 mRNA

NCBI chr17:41,619,442...41,624,575
Ensembl chr17:41,619,442...41,624,842

G

keratin 18

increases expression

Selenium results in increased expression of KRT18 mRNA

NCBI chr12:52,948,855...52,952,906
Ensembl chr12:52,948,871...52,952,906

G

keratin 19

increases expression

Selenium results in increased expression of KRT19 mRNA

NCBI chr17:41,523,617...41,528,308
Ensembl chr17:41,523,617...41,528,308

G

keratin 7

increases expression

Selenium results in increased expression of KRT7 mRNA

NCBI chr12:52,233,243...52,255,853
Ensembl chr12:52,232,520...52,252,186

G

keratin 8

increases expression

Selenium results in increased expression of KRT8 mRNA

NCBI chr12:52,897,191...52,949,860
Ensembl chr12:52,897,187...52,949,954

G

kinectin 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of KTN1 mRNA
Selenium results in decreased expression of KTN1 mRNA

NCBI chr14:55,580,207...55,684,584
Ensembl chr14:55,559,072...55,701,526

G

laminin subunit beta 3

increases expression

Selenium results in increased expression of LAMB3 mRNA

NCBI chr 1:209,614,870...209,652,425
Ensembl chr 1:209,614,870...209,652,425

G

lysosomal associated membrane protein 1

increases expression

Selenium results in increased expression of LAMP1 mRNA

NCBI chr13:113,297,239...113,323,672
Ensembl chr13:113,297,239...113,323,672

G

La ribonucleoprotein 4B

increases expression

Selenium results in increased expression of LARP4B mRNA

NCBI chr10:806,914...988,341
Ensembl chr10:806,933...931,821

G

LBH domain containing 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of LBHD1 mRNA
Selenium results in decreased expression of LBHD1 mRNA

NCBI chr11:62,662,817...62,672,267
Ensembl chr11:62,662,817...62,672,267

G

lecithin-cholesterol acyltransferase

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in decreased expression of LCAT mRNA]

NCBI chr16:67,939,750...67,944,120
Ensembl chr16:67,939,750...67,944,131

G

low density lipoprotein receptor

multiple interactions
increases expression
increases activity
decreases activity
decreases expression

Selenium inhibits the reaction [Cholesterol results in decreased activity of LDLR protein]; Selenium inhibits the reaction [Cholesterol results in decreased expression of LDLR mRNA]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LDLR mRNA]
Selenium results in increased expression of LDLR mRNA
Selenium results in increased activity of LDLR protein
Selenium deficiency results in decreased activity of LDLR protein
Selenium deficiency results in decreased expression of LDLR mRNA

PMID:16271152 PMID:16317514 PMID:16937255 PMID:36464106

NCBI chr19:11,089,463...11,133,820
Ensembl chr19:11,089,418...11,133,820

G

low density lipoprotein receptor class A domain containing 4

increases expression

Selenium results in increased expression of LDLRAD4 mRNA

NCBI chr18:13,217,682...13,652,754
Ensembl chr18:13,217,498...13,652,755

G

low density lipoprotein receptor adaptor protein 1

increases expression

Selenium results in increased expression of ARH mRNA

NCBI chr 1:25,543,606...25,590,400
Ensembl chr 1:25,543,606...25,568,886

G

leptin

decreases abundance

LEP gene mutant form results in decreased abundance of Selenium

NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629

G

luteinizing hormone subunit beta

multiple interactions

Selenium inhibits the reaction [Cadmium Chloride results in decreased expression of LHB protein]

NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091

G

LIM and calponin homology domains 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of LIMCH1 mRNA
Selenium results in decreased expression of LIMCH1 mRNA

NCBI chr 4:41,359,607...41,700,044
Ensembl chr 4:41,359,607...41,700,044

G

Lck interacting transmembrane adaptor 1

increases expression

Selenium results in increased expression of LIME1 mRNA

NCBI chr20:63,735,701...63,739,103
Ensembl chr20:63,736,283...63,739,103

G

lipoyltransferase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of LIPT1 mRNA
Selenium results in decreased expression of LIPT1 mRNA

NCBI chr 2:99,154,967...99,163,137
Ensembl chr 2:99,154,955...99,163,157

G

lipopolysaccharide induced TNF factor

increases expression

Selenium results in increased expression of LITAF mRNA

NCBI chr16:11,547,722...11,640,317
Ensembl chr16:11,547,722...11,636,381

G

lectin, mannose binding 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of LMAN2 mRNA
Selenium results in increased expression of LMAN2 mRNA

NCBI chr 5:177,331,567...177,351,668
Ensembl chr 5:177,315,805...177,351,840

G

lamin A/C

increases expression

Selenium results in increased expression of LMNA mRNA

NCBI chr 1:156,082,573...156,140,081
Ensembl chr 1:156,082,573...156,140,081

G

lysophosphatidic acid receptor 1

increases expression

Selenium results in increased expression of LPAR1 mRNA

NCBI chr 9:110,873,263...111,038,998
Ensembl chr 9:110,873,263...111,038,470

G

lysophosphatidic acid receptor 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of LPAR2 mRNA

NCBI chr19:19,623,655...19,628,220
Ensembl chr19:19,623,655...19,628,930

G

lipin 1

decreases expression
multiple interactions

Selenium results in decreased expression of LPIN1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of LPIN1 mRNA]

PMID:19244175 PMID:36464106

NCBI chr 2:11,677,544...11,827,409
Ensembl chr 2:11,677,595...11,827,409

G

LDL receptor related protein 8

affects response to substance
affects abundance
increases uptake

LRP8 protein affects the susceptibility to Selenium
LRP8 protein affects the abundance of Selenium
LRP8 protein results in increased uptake of Selenium

PMID:17314095 PMID:17553992 PMID:18172410 PMID:19007311

NCBI chr 1:53,242,364...53,328,070
Ensembl chr 1:53,242,364...53,328,469

G

leucine rich repeat containing 41

increases expression

Selenium results in increased expression of LRRC41 mRNA

NCBI chr 1:46,277,462...46,303,616
Ensembl chr 1:46,261,196...46,303,616

G

leucine rich repeat containing 47

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of LRRC47 mRNA

NCBI chr 1:3,778,559...3,796,498
Ensembl chr 1:3,778,559...3,796,498

G

LRR binding FLII interacting protein 1

decreases expression

Selenium results in decreased expression of LRRFIP1 mRNA

NCBI chr 2:237,627,587...237,781,643
Ensembl chr 2:237,627,587...237,813,682

G

lymphocyte specific protein 1

increases expression

Selenium results in increased expression of LSP1 mRNA

NCBI chr11:1,853,084...1,892,263
Ensembl chr11:1,850,904...1,892,267

G

lipolysis stimulated lipoprotein receptor

increases expression

Selenium results in increased expression of LSR mRNA

NCBI chr19:35,249,002...35,267,964
Ensembl chr19:35,248,330...35,267,964

G

latent transforming growth factor beta binding protein 3

increases expression

Selenium results in increased expression of LTBP3 mRNA

NCBI chr11:65,538,559...65,558,359
Ensembl chr11:65,538,559...65,558,930

G

latent transforming growth factor beta binding protein 4

increases expression

Selenium results in increased expression of LTBP4 mRNA

NCBI chr19:40,593,166...40,629,820
Ensembl chr19:40,592,883...40,629,818

G

lymphotoxin beta receptor

increases expression

Selenium results in increased expression of LTBR mRNA

NCBI chr12:6,375,160...6,391,566
Ensembl chr12:6,375,045...6,391,571

G

LUC7 like 2, pre-mRNA splicing factor

decreases expression

Selenium results in decreased expression of LUC7L2 mRNA

NCBI chr 7:139,340,472...139,423,454
Ensembl chr 7:139,340,359...139,423,457

G

LUC7 like 3 pre-mRNA splicing factor

decreases expression

Selenium results in decreased expression of LUC7L3 mRNA

NCBI chr17:50,719,603...50,756,219
Ensembl chr17:50,719,565...50,756,219

G

lymphocyte antigen 6 family member E

increases expression

Selenium results in increased expression of LY6E mRNA

NCBI chr 8:143,018,529...143,022,409
Ensembl chr 8:143,017,982...143,023,832

G

lysophospholipase 1

decreases expression

Selenium results in decreased expression of LYPLA1 mRNA

NCBI chr 8:54,046,367...54,101,947
Ensembl chr 8:54,046,367...54,102,017

G

lysophospholipase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of LYPLA2 mRNA
Selenium results in increased expression of LYPLA2 mRNA

NCBI chr 1:23,791,145...23,795,539
Ensembl chr 1:23,791,145...23,795,539

G

microtubule actin crosslinking factor 1

decreases expression

Selenium results in decreased expression of MACF1 mRNA

NCBI chr 1:39,084,167...39,487,138
Ensembl chr 1:39,081,316...39,487,177

G

macrophage immunometabolism regulator

decreases expression

Selenium results in decreased expression of MACIR mRNA

NCBI chr 5:103,258,374...103,278,660
Ensembl chr 5:103,258,763...103,278,660

G

macroH2A.2 histone

increases expression

Selenium results in increased expression of MACROH2A2 mRNA

NCBI chr10:70,052,846...70,112,282
Ensembl chr10:70,052,544...70,112,282

G

MAGE family member D2

increases expression

Selenium results in increased expression of MAGED2 mRNA

NCBI chr X:54,807,745...54,816,015
Ensembl chr X:54,807,599...54,816,015

G

membrane associated guanylate kinase, WW and PDZ domain containing 2

decreases expression

Selenium results in decreased expression of MAGI2 mRNA

NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667

G

mal, T cell differentiation protein like

increases expression

Selenium results in increased expression of MALL mRNA

NCBI chr 2:110,083,870...110,118,139
Ensembl chr 2:110,083,870...110,116,022

G

MALT1 paracaspase

decreases expression

Selenium results in decreased expression of MALT1 mRNA

NCBI chr18:58,671,465...58,754,477
Ensembl chr18:58,671,465...58,754,477

G

mannosidase alpha class 1B member 1

increases expression

Selenium results in increased expression of MAN1B1 mRNA

NCBI chr 9:137,086,985...137,109,183
Ensembl chr 9:137,086,857...137,109,189

G

mannosidase alpha class 2B member 1

increases expression

Selenium results in increased expression of MAN2B1 mRNA

NCBI chr19:12,646,512...12,666,742
Ensembl chr19:12,646,511...12,666,742

G

mitogen-activated protein kinase kinase 2

increases expression

Selenium results in increased expression of MAP2K2 mRNA

NCBI chr19:4,090,321...4,124,122
Ensembl chr19:4,090,321...4,124,122

G

mitogen-activated protein kinase kinase 3

increases expression

Selenium results in increased expression of MAP2K3 mRNA

NCBI chr17:21,284,711...21,315,240
Ensembl chr17:21,284,672...21,315,232

G

mitogen-activated protein kinase kinase kinase 5

decreases expression

Selenium results in decreased expression of MAP3K5 mRNA

NCBI chr 6:136,557,046...136,793,091
Ensembl chr 6:136,557,046...136,793,097

G

mitogen-activated protein kinase kinase kinase 7

decreases expression

Selenium results in decreased expression of MAP3K7 mRNA

NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086

G

mitogen-activated protein kinase kinase kinase 8

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of MAP3K8 mRNA
Selenium results in decreased expression of MAP3K8 mRNA

NCBI chr10:30,434,021...30,461,833
Ensembl chr10:30,434,021...30,461,833

G

microtubule associated protein 4

increases expression

Selenium results in increased expression of MAP4 mRNA

NCBI chr 3:47,850,695...48,088,848
Ensembl chr 3:47,850,690...48,089,272

G

mitogen-activated protein kinase kinase kinase kinase 5

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of MAP4K5 mRNA

NCBI chr14:50,418,521...50,561,126
Ensembl chr14:50,418,501...50,561,126

G

MAP7 domain containing 1

increases expression

Selenium results in increased expression of MAP7D1 mRNA

NCBI chr 1:36,156,160...36,180,849
Ensembl chr 1:36,155,579...36,180,849

G

mitogen-activated protein kinase 1

multiple interactions

Selenium results in increased phosphorylation of and results in increased activity of MAPK1 protein

NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680

G

mitogen-activated protein kinase 11

increases expression

Selenium results in increased expression of MAPK11 mRNA

NCBI chr22:50,263,713...50,270,380
Ensembl chr22:50,263,713...50,270,767

G

mitogen-activated protein kinase 3

multiple interactions

Selenium results in increased phosphorylation of and results in increased activity of MAPK3 protein
Selenium inhibits the reaction [arsenite results in decreased expression of MAPK3 protein]

PMID:17997286 PMID:29324385

NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506

G

mitogen-activated protein kinase 8

decreases phosphorylation
decreases expression
multiple interactions

Selenium results in decreased phosphorylation of MAPK8 protein
Selenium results in decreased expression of MAPK8 mRNA
Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]

PMID:17997286 PMID:26187450 PMID:28810182

NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360

G

mitogen-activated protein kinase 9

multiple interactions

Selenium inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]

NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099

G

microtubule associated protein tau

multiple interactions

Selenium inhibits the reaction [[Dietary Fats co-treated with Cholesterol] results in increased expression of MAPT protein modified form]

NCBI chr17:45,894,554...46,028,334
Ensembl chr17:45,894,527...46,028,334

G

membrane associated ring-CH-type finger 2

increases expression

Selenium results in increased expression of MARCHF2 mRNA

NCBI chr19:8,413,305...8,439,017
Ensembl chr19:8,413,270...8,439,017

G

membrane associated ring-CH-type finger 6

decreases expression

Selenium results in decreased expression of MARCHF6 mRNA

NCBI chr 5:10,353,695...10,440,388
Ensembl chr 5:10,353,695...10,440,388

G

myristoylated alanine rich protein kinase C substrate

increases expression

Selenium results in increased expression of MARCKS mRNA

NCBI chr 6:113,857,345...113,863,475
Ensembl chr 6:113,857,345...113,863,475

G

MAU2 sister chromatid cohesion factor

decreases expression

Selenium results in decreased expression of MAU2 mRNA

NCBI chr19:19,320,829...19,358,754
Ensembl chr19:19,320,829...19,358,754

G

MYC associated factor X

increases expression

Selenium results in increased expression of MAX mRNA

NCBI chr14:65,006,101...65,102,695
Ensembl chr14:65,006,174...65,102,695

G

MYC associated zinc finger protein

increases expression

Selenium results in increased expression of MAZ mRNA

NCBI chr16:29,806,124...29,811,164
Ensembl chr16:29,806,106...29,811,164

G

methyl-CpG binding domain protein 1

decreases expression

Selenium results in decreased expression of MBD1 mRNA

NCBI chr18:50,266,885...50,281,767
Ensembl chr18:50,266,882...50,281,774

G

methyl-CpG binding domain protein 3

increases expression

Selenium results in increased expression of MBD3 mRNA

NCBI chr19:1,573,596...1,592,865
Ensembl chr19:1,573,596...1,592,865

G

methyl-CpG binding domain 4, DNA glycosylase

decreases expression

Selenium results in decreased expression of MBD4 mRNA

NCBI chr 3:129,430,947...129,439,948
Ensembl chr 3:129,430,947...129,440,179

G

muscleblind like splicing regulator 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of MBNL1 mRNA
Selenium results in decreased expression of MBNL1 mRNA

NCBI chr 3:152,243,632...152,465,780
Ensembl chr 3:152,243,828...152,465,780

G

myelin basic protein

multiple interactions

Selenium inhibits the reaction [Iodine results in decreased expression of MBP mRNA]

NCBI chr18:76,978,833...77,133,708
Ensembl chr18:76,978,827...77,133,683

G

methylcrotonyl-CoA carboxylase subunit 1

decreases expression

Selenium results in decreased expression of MCCC1 mRNA

NCBI chr 3:183,015,218...183,116,196
Ensembl chr 3:183,015,218...183,116,075

G

MCF.2 cell line derived transforming sequence like

increases expression

Selenium results in increased expression of MCF2L mRNA

NCBI chr13:112,894,335...113,099,742
Ensembl chr13:112,894,378...113,099,742

G

minichromosome maintenance complex component 5

increases expression

Selenium results in increased expression of MCM5 mRNA

NCBI chr22:35,400,140...35,455,031
Ensembl chr22:35,400,134...35,425,431

G

minichromosome maintenance complex component 7

increases expression

Selenium results in increased expression of MCM7 mRNA

NCBI chr 7:100,092,728...100,101,397
Ensembl chr 7:100,092,233...100,101,940

G

microspherule protein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MCRS1 mRNA
Selenium results in increased expression of MCRS1 mRNA

NCBI chr12:49,558,299...49,568,142
Ensembl chr12:49,556,544...49,568,145

G

midkine

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MDK mRNA
Selenium results in increased expression of MDK mRNA

NCBI chr11:46,380,784...46,383,837
Ensembl chr11:46,380,756...46,383,837

G

Mdm1 nuclear protein

decreases expression
multiple interactions

Selenium results in decreased expression of MDM1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of MDM1 mRNA

NCBI chr12:68,294,566...68,332,362
Ensembl chr12:68,272,443...68,332,381

G

malic enzyme 1

decreases expression

Selenium results in decreased expression of ME1 mRNA

NCBI chr 6:83,210,402...83,431,051
Ensembl chr 6:83,210,402...83,431,051

G

mediator complex subunit 13L

decreases expression

Selenium results in decreased expression of MED13L mRNA

NCBI chr12:115,958,576...116,277,693
Ensembl chr12:115,957,905...116,277,693

G

mediator complex subunit 15

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MED15 mRNA
Selenium results in increased expression of MED15 mRNA

NCBI chr22:20,507,610...20,587,619
Ensembl chr22:20,495,913...20,587,632

G

mediator complex subunit 24

increases expression

Selenium results in increased expression of MED24 mRNA

NCBI chr17:40,019,104...40,054,408
Ensembl chr17:40,019,097...40,061,215

G

methionyl aminopeptidase 2

decreases expression

Selenium results in decreased expression of METAP2 mRNA

NCBI chr12:95,474,152...95,515,839
Ensembl chr12:95,473,520...95,515,839

G

microfibril associated protein 2

increases expression

Selenium results in increased expression of MFAP2 mRNA

NCBI chr 1:16,974,502...16,981,583
Ensembl chr 1:16,974,502...16,980,632

G

milk fat globule EGF and factor V/VIII domain containing

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of MFGE8 mRNA

NCBI chr15:88,898,683...88,913,379
Ensembl chr15:88,898,683...88,913,468

G

major facilitator superfamily domain containing 10

increases expression

Selenium results in increased expression of MFSD10 mRNA

NCBI chr 4:2,930,567...2,934,825
Ensembl chr 4:2,930,561...2,934,834

G

alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase

increases expression

Selenium results in increased expression of MGAT1 mRNA

NCBI chr 5:180,784,780...180,815,616
Ensembl chr 5:180,784,780...180,815,652

G

migration and invasion inhibitory protein

increases expression

Selenium results in increased expression of MIIP mRNA

NCBI chr 1:12,019,498...12,032,045
Ensembl chr 1:12,019,466...12,032,045

G

misshapen like kinase 1

increases expression

Selenium results in increased expression of MINK1 mRNA

NCBI chr17:4,833,340...4,898,061
Ensembl chr17:4,833,340...4,898,061

G

meiosis regulator for oocyte development

decreases expression

Selenium results in decreased expression of MIOS mRNA

NCBI chr 7:7,566,884...7,609,144
Ensembl chr 7:7,566,875...7,608,932

G

MIS12 kinetochore complex component

decreases expression

Selenium results in decreased expression of MIS12 mRNA

NCBI chr17:5,486,374...5,490,811
Ensembl chr17:5,486,285...5,490,814

G

mitotic spindle positioning

increases expression

Selenium results in increased expression of MISP mRNA

NCBI chr19:748,438...764,318
Ensembl chr19:751,112...764,318

G

malectin

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of MLEC mRNA
Selenium results in increased expression of MLEC mRNA
Selenium results in decreased expression of MLEC mRNA

NCBI chr12:120,687,149...120,701,859
Ensembl chr12:120,687,149...120,701,859

G

myeloid leukemia factor 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MLF2 mRNA
Selenium results in increased expression of MLF2 mRNA

NCBI chr12:6,747,996...6,753,141
Ensembl chr12:6,747,996...6,767,475

G

MTOR associated protein, LST8 homolog

increases expression

Selenium results in increased expression of MLST8 mRNA

NCBI chr16:2,205,454...2,209,453
Ensembl chr16:2,204,248...2,209,453

G

membrane metalloendopeptidase

multiple interactions

Selenium deficiency affects the expression of and affects the localization of MME protein

NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704

G

matrix metallopeptidase 13

multiple interactions

Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 mRNA]; Selenium inhibits the reaction [T-2 Toxin results in increased expression of MMP13 protein]

NCBI chr11:102,942,995...102,955,732
Ensembl chr11:102,942,995...102,955,732

G

matrix metallopeptidase 14

decreases expression

Selenium results in decreased expression of MMP14 mRNA

NCBI chr14:22,836,585...22,847,758
Ensembl chr14:22,836,560...22,849,041

G

matrix metallopeptidase 15

decreases expression

Selenium results in decreased expression of MMP15 mRNA

NCBI chr16:58,025,754...58,046,901
Ensembl chr16:58,025,754...58,046,901

G

matrix metallopeptidase 16

decreases expression

Selenium results in decreased expression of MMP16 mRNA

NCBI chr 8:88,032,011...88,327,483
Ensembl chr 8:88,032,011...88,328,025

G

matrix metallopeptidase 2

decreases expression
increases expression

Selenium results in decreased expression of MMP2 mRNA
Selenium results in increased expression of MMP2 mRNA

PMID:17390030 PMID:19244175

NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691

G

matrix metallopeptidase 24

decreases expression
increases expression

Selenium results in decreased expression of MMP24 mRNA
Selenium results in increased expression of MMP24 mRNA

PMID:17390030 PMID:19244175

NCBI chr20:35,226,690...35,276,998
Ensembl chr20:35,226,690...35,276,998

G

matrix metallopeptidase 9

decreases expression

Selenium results in decreased expression of MMP9 mRNA

NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561

G

MMS19 homolog, cytosolic iron-sulfur assembly component

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MMS19 mRNA
Selenium results in increased expression of MMS19 mRNA

NCBI chr10:97,458,324...97,498,794
Ensembl chr10:97,458,324...97,498,794

G

methylmalonyl-CoA mutase

decreases expression

Selenium results in decreased expression of MMUT mRNA

NCBI chr 6:49,430,360...49,463,253
Ensembl chr 6:49,430,360...49,463,253

G

MON1 homolog B, secretory trafficking associated

increases expression

Selenium results in increased expression of MON1B mRNA

NCBI chr16:77,191,190...77,202,398
Ensembl chr16:77,190,835...77,202,398

G

MON2 homolog, regulator of endosome-to-Golgi trafficking

decreases expression

Selenium results in decreased expression of MON2 mRNA

NCBI chr12:62,466,826...62,600,476
Ensembl chr12:62,466,817...62,600,476

G

mercaptopyruvate sulfurtransferase

increases expression
multiple interactions

Selenium results in increased expression of MPST mRNA
[Selenium co-treated with Vitamin E] results in increased expression of MPST mRNA

NCBI chr22:37,019,742...37,029,815
Ensembl chr22:37,019,635...37,029,821

G

mitochondrial inner membrane protein MPV17

increases expression

Selenium results in increased expression of MPV17 mRNA

NCBI chr 2:27,309,492...27,323,097
Ensembl chr 2:27,309,492...27,325,680

G

mannose receptor C-type 1

multiple interactions

2-chloro-5-nitrobenzanilide inhibits the reaction [[Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA]; [Selenium co-treated with IL4 protein] results in increased expression of MRC1 mRNA

NCBI chr10:17,809,348...17,911,164
Ensembl chr10:17,809,348...17,911,164

G

mitochondrial ribosomal protein L12

increases expression

Selenium results in increased expression of MRPL12 mRNA

NCBI chr17:81,703,367...81,707,517
Ensembl chr17:81,703,367...81,707,517

G

mitochondrial ribosomal protein L2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MRPL2 mRNA
Selenium results in increased expression of MRPL2 mRNA

NCBI chr 6:43,054,029...43,059,863
Ensembl chr 6:43,054,029...43,059,438

G

mitochondrial ribosomal protein L34

increases expression

Selenium results in increased expression of MRPL34 mRNA

NCBI chr19:17,292,573...17,306,843
Ensembl chr19:17,292,609...17,306,843

G

mitochondrial ribosomal protein L4

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MRPL4 mRNA
Selenium results in increased expression of MRPL4 mRNA

NCBI chr19:10,251,951...10,260,055
Ensembl chr19:10,251,901...10,260,055

G

mitochondrial ribosomal protein L44

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of MRPL44 mRNA
Selenium results in decreased expression of MRPL44 mRNA

NCBI chr 2:223,950,854...223,967,714
Ensembl chr 2:223,957,463...223,967,714

G

mitochondrial ribosomal protein L49

increases expression

Selenium results in increased expression of MRPL49 mRNA

NCBI chr11:65,122,183...65,127,371
Ensembl chr11:65,122,183...65,127,371

G

mitochondrial ribosomal protein L9

increases expression

Selenium results in increased expression of MRPL9 mRNA

NCBI chr 1:151,759,647...151,763,496
Ensembl chr 1:151,759,647...151,763,496

G

mitochondrial ribosomal protein S33

decreases expression

Selenium results in decreased expression of MRPS33 mRNA

NCBI chr 7:141,002,610...141,014,952
Ensembl chr 7:141,002,610...141,015,228

G

mutS homolog 5

decreases expression

Selenium results in decreased expression of MSH5 mRNA

NCBI chr 6:31,740,005...31,762,676
Ensembl chr 6:31,739,677...31,762,676

G

moesin

increases expression

Selenium results in increased expression of MSN mRNA

NCBI chr X:65,588,377...65,741,931
Ensembl chr X:65,588,377...65,741,931

G

methionine sulfoxide reductase B1

decreases expression
multiple interactions

Selenium deficiency results in decreased expression of MSRB1 mRNA
Selenium deficiency results in decreased expression of and results in decreased activity of MSRB1 protein

PMID:12792026 PMID:16170372

NCBI chr16:1,938,229...1,943,199
Ensembl chr16:1,938,229...1,943,199

G

metallothionein 3

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of MT3 mRNA

NCBI chr16:56,589,528...56,591,085
Ensembl chr16:56,589,074...56,591,088

G

mitochondrial carrier 2

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of MTCH2 mRNA

NCBI chr11:47,604,317...47,642,559
Ensembl chr11:47,617,315...47,642,607

G

metal regulatory transcription factor 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of MTF1 mRNA

NCBI chr 1:37,809,574...37,859,592
Ensembl chr 1:37,809,574...37,859,592

G

metal response element binding transcription factor 2

decreases expression

Selenium results in decreased expression of MTF2 mRNA

NCBI chr 1:93,079,283...93,139,076
Ensembl chr 1:93,079,235...93,139,079

G

myotubularin related protein 9

decreases expression

Selenium results in decreased expression of MTMR9 mRNA

NCBI chr 8:11,284,816...11,339,526
Ensembl chr 8:11,284,816...11,328,146

G

mechanistic target of rapamycin kinase

multiple interactions

Selenium inhibits the reaction [arsenite results in decreased expression of and results in decreased phosphorylation of MTOR protein]

NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556

G

mucin 4, cell surface associated

increases expression

Selenium results in increased expression of MUC4 mRNA

NCBI chr 3:195,746,771...195,811,929
Ensembl chr 3:195,746,765...195,811,973

G

mucin 5AC, oligomeric mucus/gel-forming

decreases expression

Selenium results in decreased expression of MUC5AC mRNA

NCBI chr11:1,157,953...1,201,138
Ensembl chr11:1,157,953...1,201,138

G

mevalonate kinase

increases expression

Selenium results in increased expression of MVK mRNA

NCBI chr12:109,573,272...109,598,125
Ensembl chr12:109,573,255...109,598,125

G

major vault protein

increases expression

Selenium results in increased expression of MVP mRNA

NCBI chr16:29,820,394...29,848,039
Ensembl chr16:29,820,394...29,848,039

G

MX dynamin like GTPase 1

increases expression

Selenium results in increased expression of MX1 mRNA

NCBI chr21:41,420,558...41,459,214
Ensembl chr21:41,420,020...41,470,071

G

MYC proto-oncogene, bHLH transcription factor

decreases expression
multiple interactions

Selenium deficiency results in decreased expression of MYC mRNA; Selenium results in decreased expression of MYC mRNA
Selenium inhibits the reaction [Cadmium Chloride results in increased expression of MYC protein]

PMID:11925459 PMID:16600092 PMID:17948765

NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951

G

myosin heavy chain 9

increases expression

Selenium results in increased expression of MYH9 mRNA

NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010

G

myosin light chain 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MYL6 mRNA
Selenium results in increased expression of MYL6 mRNA

NCBI chr12:56,158,359...56,161,579
Ensembl chr12:56,158,346...56,163,496

G

myosin XVIIIA

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of MYO18A mRNA
Selenium results in increased expression of MYO18A mRNA

NCBI chr17:29,071,122...29,180,398
Ensembl chr17:29,071,122...29,180,398

G

myosin VI

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of MYO6 mRNA
Selenium results in decreased expression of MYO6 mRNA

NCBI chr 6:75,749,239...75,919,537
Ensembl chr 6:75,749,201...75,919,537

G

myeloid zinc finger 1

increases expression

Selenium results in increased expression of MZF1 mRNA

NCBI chr19:58,561,932...58,573,573
Ensembl chr19:58,561,931...58,573,575

G

NEDD4 binding protein 2 like 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of N4BP2L2 mRNA
Selenium results in decreased expression of N4BP2L2 mRNA

NCBI chr13:32,432,485...32,538,868
Ensembl chr13:32,432,417...32,538,885

G

N-alpha-acetyltransferase 10, NatA catalytic subunit

increases expression

Selenium results in increased expression of NAA10 mRNA

NCBI chr X:153,929,225...153,935,037
Ensembl chr X:153,929,225...153,935,080

G

nascent polypeptide associated complex subunit alpha

decreases expression

Selenium results in decreased expression of NACA mRNA

NCBI chr12:56,712,427...56,725,299
Ensembl chr12:56,712,305...56,731,628

G

N-acetylglucosamine kinase

increases expression

Selenium results in increased expression of NAGK mRNA

NCBI chr 2:71,068,296...71,079,808
Ensembl chr 2:71,064,344...71,079,808

G

N-acetyl-alpha-glucosaminidase

increases expression

Selenium results in increased expression of NAGLU mRNA

NCBI chr17:42,536,241...42,544,449
Ensembl chr17:42,536,241...42,544,449

G

NSF attachment protein alpha

increases expression

Selenium results in increased expression of NAPA mRNA

NCBI chr19:47,484,530...47,515,063
Ensembl chr19:47,487,637...47,515,091

G

nuclear autoantigenic sperm protein

increases expression

Selenium results in increased expression of NASP mRNA

NCBI chr 1:45,584,041...45,618,893
Ensembl chr 1:45,583,846...45,618,904

G

neuron navigator 2

decreases expression

Selenium results in decreased expression of NAV2 mRNA

NCBI chr11:19,345,236...20,121,601
Ensembl chr11:19,350,724...20,121,601

G

neurochondrin

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of NCDN mRNA
Selenium results in increased expression of NCDN mRNA

NCBI chr 1:35,557,799...35,566,779
Ensembl chr 1:35,557,473...35,567,274

G

nuclear receptor coactivator 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of NCOA2 mRNA
Selenium results in decreased expression of NCOA2 mRNA

NCBI chr 8:70,109,782...70,456,446
Ensembl chr 8:70,109,782...70,403,808

G

NADH:ubiquinone oxidoreductase subunit A1

decreases expression

Selenium results in decreased expression of NDUFA1 mRNA

NCBI chr X:119,871,832...119,876,662
Ensembl chr X:119,871,832...119,876,662

G

NDUFA4 mitochondrial complex associated

decreases expression

Selenium results in decreased expression of NDUFA4 mRNA

NCBI chr 7:10,931,943...10,940,153
Ensembl chr 7:10,931,943...10,940,153

G

NADH:ubiquinone oxidoreductase subunit A7

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of NDUFA7 mRNA

NCBI chr19:8,308,595...8,321,375
Ensembl chr19:8,308,768...8,321,375

G

NADH:ubiquinone oxidoreductase subunit B1

decreases expression

Selenium results in decreased expression of NDUFB1 mRNA

NCBI chr14:92,116,123...92,121,706
Ensembl chr14:92,116,122...92,121,917

G

NADH:ubiquinone oxidoreductase subunit B2

decreases expression

Selenium results in decreased expression of NDUFB2 mRNA

NCBI chr 7:140,696,708...140,706,643
Ensembl chr 7:140,690,777...140,722,790

G

NADH:ubiquinone oxidoreductase core subunit S3

increases expression

Selenium results in increased expression of NDUFS3 mRNA

NCBI chr11:47,579,074...47,584,562
Ensembl chr11:47,565,336...47,584,562

G

NADH:ubiquinone oxidoreductase subunit S4

decreases expression

Selenium results in decreased expression of NDUFS4 mRNA

NCBI chr 5:53,560,639...53,683,338
Ensembl chr 5:53,560,633...53,683,338

G

NADH:ubiquinone oxidoreductase core subunit V1

increases expression

Selenium results in increased expression of NDUFV1 mRNA

NCBI chr11:67,606,936...67,612,554
Ensembl chr11:67,605,653...67,612,554

G

nectin cell adhesion molecule 2

increases expression

Selenium results in increased expression of NECTIN2 mRNA

NCBI chr19:44,846,297...44,889,223
Ensembl chr19:44,846,175...44,889,223

G

NEDD8 ubiquitin like modifier

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of NEDD8 mRNA

NCBI chr14:24,216,857...24,232,367
Ensembl chr14:24,216,857...24,232,367

G

NIMA related kinase 1

decreases expression
multiple interactions

Selenium results in decreased expression of NEK1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of NEK1 mRNA

NCBI chr 4:169,392,809...169,612,583
Ensembl chr 4:169,369,704...169,612,632

G

NIMA related kinase 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of NEK2 mRNA
Selenium results in decreased expression of NEK2 mRNA

NCBI chr 1:211,658,256...211,675,621
Ensembl chr 1:211,658,657...211,675,630

G

negative elongation factor complex member A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of NELFA mRNA
Selenium results in increased expression of NELFA mRNA

NCBI chr 4:1,982,723...2,008,974
Ensembl chr 4:1,982,717...2,041,903

G

NF2, moesin-ezrin-radixin like (MERLIN) tumor suppressor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of NF2 mRNA
Selenium results in increased expression of NF2 mRNA

NCBI chr22:29,603,556...29,698,600
Ensembl chr22:29,603,556...29,698,598

G

nuclear factor of activated T cells 5

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of NFAT5 mRNA
Selenium results in decreased expression of NFAT5 mRNA

NCBI chr16:69,565,966...69,704,654
Ensembl chr16:69,565,094...69,704,666

G

NFE2 like bZIP transcription factor 2

decreases expression
multiple interactions
affects activity

Selenium results in decreased expression of NFE2L2 mRNA
[Aluminum co-treated with Lead co-treated with Mercury co-treated with Manganese co-treated with Selenium] results in decreased expression of NFE2L2 protein
Selenium affects the activity of NFE2L2 protein
NFE2L2 protein affects the reaction [Selenium affects the activity of HMOX1 protein]
[Selenium co-treated with Vitamin E] results in decreased expression of NFE2L2 mRNA

PMID:18279678 PMID:19244175 PMID:37415728

NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756

G

nuclear factor I C

increases expression

Selenium results in increased expression of NFIC mRNA

NCBI chr19:3,359,630...3,469,217
Ensembl chr19:3,314,403...3,469,217

G

nuclear factor kappa B subunit 2

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of NFKB2 mRNA

NCBI chr10:102,394,110...102,402,529
Ensembl chr10:102,394,110...102,402,524

G

NFKB inhibitor alpha

multiple interactions

[Drugs, Chinese Herbal co-treated with Selenium] inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of and results in increased degradation of NFKBIA protein]; Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased degradation of NFKBIA protein]; Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in decreased expression of NFKBIA protein]
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of NFKBIA mRNA

PMID:17439952 PMID:17630198 PMID:21481475 PMID:24626144

NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749

G

NFKB inhibitor beta

increases expression

Selenium results in increased expression of NFKBIB mRNA

NCBI chr19:38,899,666...38,908,889
Ensembl chr19:38,899,700...38,908,893

G

NFS1 cysteine desulfurase

decreases expression

Selenium results in decreased expression of NFS1 mRNA

NCBI chr20:35,668,052...35,699,352
Ensembl chr20:35,668,052...35,699,355

G

niban apoptosis regulator 1

decreases expression

Selenium results in decreased expression of NIBAN1 mRNA

NCBI chr 1:184,791,032...184,974,508
Ensembl chr 1:184,790,724...184,974,508

G

nidogen 2

decreases expression

Selenium results in decreased expression of NID2 mRNA

NCBI chr14:52,004,809...52,069,059
Ensembl chr14:52,004,809...52,069,059

G

ninjurin 1

increases expression

Selenium results in increased expression of NINJ1 mRNA

NCBI chr 9:93,121,496...93,134,251
Ensembl chr 9:93,121,496...93,134,251

G

NIPBL cohesin loading factor

decreases expression

Selenium results in decreased expression of NIPBL mRNA

NCBI chr 5:36,876,769...37,066,413
Ensembl chr 5:36,876,769...37,066,413

G

natural killer cell triggering receptor

decreases expression

Selenium results in decreased expression of NKTR mRNA

NCBI chr 3:42,600,612...42,648,735
Ensembl chr 3:42,600,655...42,648,735

G

NLR family pyrin domain containing 3

increases expression

Selenium results in increased expression of NLRP3 mRNA

NCBI chr 1:247,416,077...247,448,817
Ensembl chr 1:247,416,156...247,449,108

G

NOC3 like DNA replication regulator

decreases expression

Selenium results in decreased expression of NOC3L mRNA

NCBI chr10:94,314,907...94,362,939
Ensembl chr10:94,333,226...94,362,959

G

nucleolar protein 3

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of NOL3 mRNA

NCBI chr16:67,170,538...67,175,737
Ensembl chr16:67,170,154...67,175,737

G

nucleolar protein 8

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of NOL8 mRNA
Selenium results in decreased expression of NOL8 mRNA

NCBI chr 9:92,297,358...92,325,350
Ensembl chr 9:92,297,358...92,325,636

G

nucleolar and coiled-body phosphoprotein 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of NOLC1 mRNA

NCBI chr10:102,152,389...102,163,870
Ensembl chr10:102,152,176...102,163,871

G

NODAL modulator 3

increases expression

Selenium results in increased expression of NOMO3 mRNA

NCBI chr16:16,232,528...16,294,811
Ensembl chr16:16,232,506...16,300,806

G

NOP10 ribonucleoprotein

decreases expression

Selenium results in decreased expression of NOLA3 mRNA

NCBI chr15:34,341,719...34,343,136
Ensembl chr15:34,339,159...34,343,180

G

NOP56 ribonucleoprotein

decreases expression
multiple interactions

Selenium results in decreased expression of NOP56 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of NOP56 mRNA

NCBI chr20:2,652,632...2,658,393
Ensembl chr20:2,652,593...2,658,393

G

nitric oxide synthase 2

multiple interactions

[Drugs, Chinese Herbal co-treated with Selenium] results in decreased expression of NOS2 mRNA; [Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]] which results in decreased chemical synthesis of Nitric Oxide; Selenium inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Selenium inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Selenium inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]

PMID:14734799 PMID:17630198 PMID:24626144

NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529

G

nitric oxide synthase 3

increases expression

Selenium results in increased expression of NOS3 mRNA

NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588

G

nitric oxide synthase interacting protein

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of NOSIP mRNA

NCBI chr19:49,555,468...49,580,556
Ensembl chr19:49,555,468...49,590,262

G

notch receptor 3

increases expression

Selenium results in increased expression of NOTCH3 mRNA

NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995

G

NADPH oxidase 4

increases expression

Selenium deficiency results in increased expression of NOX4 mRNA

NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187

G

aminopeptidase like 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of NPEPL1 mRNA
Selenium results in increased expression of NPEPL1 mRNA

NCBI chr20:58,689,131...58,715,844
Ensembl chr20:58,689,131...58,719,238

G

nucleophosmin 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of NPM1 mRNA

NCBI chr 5:171,387,116...171,410,900
Ensembl chr 5:171,387,116...171,411,810

G

NAD(P)H quinone dehydrogenase 1

affects activity
decreases activity
multiple interactions
increases expression

Selenium affects the activity of NQO1 protein
Selenium results in decreased activity of NQO1 protein
[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of NQO1 mRNA; Selenium promotes the reaction [Plant Extracts results in increased activity of NQO1 protein]
Selenium deficiency results in increased expression of NQO1 mRNA

PMID:11444866 PMID:18279678 PMID:19650632 PMID:28810182

NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668

G

nuclear receptor subfamily 1 group H member 3

multiple interactions

[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] affects the reaction [Dietary Fats results in increased expression of NR1H3 mRNA]

NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033

G

nuclear receptor subfamily 2 group C member 1

decreases expression

Selenium results in decreased expression of NR2C1 mRNA

NCBI chr12:95,020,229...95,073,618
Ensembl chr12:95,020,229...95,073,628

G

nuclear receptor subfamily 3 group C member 1

decreases expression

Selenium results in decreased expression of NR3C1 mRNA

NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512

G

nuclear respiratory factor 1

multiple interactions
increases expression

NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA]
Selenium results in increased expression of NRF1 mRNA

NCBI chr 7:129,611,720...129,757,076
Ensembl chr 7:129,611,720...129,757,082

G

neutral sphingomyelinase activation associated factor

decreases expression

Selenium results in decreased expression of NSMAF mRNA

NCBI chr 8:58,583,504...58,659,853
Ensembl chr 8:58,583,508...58,659,853

G

5'-nucleotidase domain containing 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of NT5DC2 mRNA
Selenium results in increased expression of NT5DC2 mRNA

NCBI chr 3:52,524,387...52,535,027
Ensembl chr 3:52,524,385...52,535,054

G

nucleobindin 1

increases expression

Selenium results in increased expression of NUCB1 mRNA

NCBI chr19:48,900,312...48,923,372
Ensembl chr19:48,900,050...48,923,473

G

nuclear casein kinase and cyclin dependent kinase substrate 1

decreases expression

Selenium results in decreased expression of NUCKS1 mRNA

NCBI chr 1:205,712,822...205,750,182
Ensembl chr 1:205,712,822...205,750,182

G

nuclear distribution C, dynein complex regulator

increases expression

Selenium results in increased expression of NUDC mRNA

NCBI chr 1:26,900,161...26,946,871
Ensembl chr 1:26,900,238...26,946,871

G

nucleoporin 93

increases expression

Selenium results in increased expression of NUP93 mRNA

NCBI chr16:56,730,129...56,850,286
Ensembl chr16:56,730,118...56,850,286

G

nuclear transport factor 2

increases expression

Selenium results in increased expression of NUTF2 mRNA

NCBI chr16:67,846,933...67,872,567
Ensembl chr16:67,846,882...67,872,567

G

ornithine decarboxylase antizyme 1

increases expression

Selenium results in increased expression of OAZ1 mRNA

NCBI chr19:2,269,486...2,273,488
Ensembl chr19:2,269,509...2,273,490

G

ornithine decarboxylase antizyme 2

increases expression

Selenium results in increased expression of OAZ2 mRNA

NCBI chr15:64,687,574...64,703,281
Ensembl chr15:64,687,573...64,703,281

G

obscurin like cytoskeletal adaptor 1

increases expression

Selenium results in increased expression of OBSL1 mRNA

NCBI chr 2:219,547,206...219,571,539
Ensembl chr 2:219,550,728...219,571,859

G

occludin

multiple interactions

[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of OCLN protein; [Selenium co-treated with gamma-Linolenic Acid] results in increased expression of and results in increased localization of OCLN protein; [Selenium co-treated with Iodine] results in increased expression of and results in increased localization of OCLN protein; Selenium results in increased expression of and results in increased localization of OCLN protein

NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104

G

opioid growth factor receptor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of OGFR mRNA
Selenium results in increased expression of OGFR mRNA

NCBI chr20:62,804,835...62,814,000
Ensembl chr20:62,804,835...62,814,000

G

8-oxoguanine DNA glycosylase

multiple interactions
increases expression

[Selenium co-treated with Arsenic] results in increased expression of OGG1 protein
Selenium results in increased expression of OGG1 protein

NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219

G

Obg like ATPase 1

decreases expression

Selenium results in decreased expression of OLA1 mRNA

NCBI chr 2:174,072,447...174,248,532
Ensembl chr 2:174,072,447...174,248,599

G

OPA1 mitochondrial dynamin like GTPase

decreases expression

Selenium results in decreased expression of OPA1 mRNA

NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811

G

optineurin

increases expression

Selenium results in increased expression of OPTN mRNA

NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308

G

orosomucoid 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of ORM1 mRNA

NCBI chr 9:114,323,098...114,326,479
Ensembl chr 9:114,323,098...114,326,479

G

OS9 endoplasmic reticulum lectin

increases expression

Selenium results in increased expression of OS9 mRNA

NCBI chr12:57,694,132...57,721,557
Ensembl chr12:57,693,841...57,728,342

G

oxysterol binding protein 2

increases expression

Selenium results in increased expression of OSBP2 mRNA

NCBI chr22:30,693,782...30,907,813
Ensembl chr22:30,693,782...30,907,824

G

oxysterol binding protein like 1A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of OSBPL1A mRNA
Selenium results in decreased expression of OSBPL1A mRNA

NCBI chr18:24,162,045...24,397,824
Ensembl chr18:24,162,045...24,397,880

G

O-sialoglycoprotein endopeptidase

increases expression

Selenium results in increased expression of OSGEP mRNA

NCBI chr14:20,446,401...20,454,812
Ensembl chr14:20,446,401...20,455,089

G

OTU deubiquitinase with linear linkage specificity like

decreases expression

Selenium results in decreased expression of OTULINL mRNA

NCBI chr 5:14,581,792...14,616,180
Ensembl chr 5:14,581,792...14,616,180

G

oviductal glycoprotein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of OVGP1 mRNA
Selenium results in increased expression of OVGP1 mRNA

NCBI chr 1:111,414,319...111,427,735
Ensembl chr 1:111,414,319...111,427,735

G

proliferation-associated 2G4

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PA2G4 mRNA

NCBI chr12:56,104,559...56,113,910
Ensembl chr12:56,104,537...56,113,910

G

platelet activating factor acetylhydrolase 1b regulatory subunit 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of PAFAH1B1 mRNA

NCBI chr17:2,593,183...2,685,615
Ensembl chr17:2,593,210...2,685,615

G

platelet activating factor acetylhydrolase 1b catalytic subunit 3

increases expression

Selenium results in increased expression of PAFAH1B3 mRNA

NCBI chr19:42,297,033...42,302,800
Ensembl chr19:42,297,033...42,303,546

G

PAGE family member 4

decreases expression

Selenium results in decreased expression of PAGE4 mRNA

NCBI chr X:49,829,260...49,834,264
Ensembl chr X:49,829,260...49,834,264

G

p21 (RAC1) activated kinase 4

increases expression

Selenium results in increased expression of PAK4 mRNA

NCBI chr19:39,125,786...39,182,816
Ensembl chr19:39,125,770...39,182,816

G

palladin, cytoskeletal associated protein

decreases expression

Selenium results in decreased expression of PALLD mRNA

NCBI chr 4:168,497,052...168,928,441
Ensembl chr 4:168,497,052...168,928,457

G

PALM2 and AKAP2 fusion

increases expression

Selenium results in increased expression of PALM2AKAP2 mRNA

NCBI chr 9:109,640,787...110,172,512
Ensembl chr 9:109,498,325...110,172,512

G

peptidylglycine alpha-amidating monooxygenase

decreases expression

Selenium results in decreased expression of PAM mRNA

NCBI chr 5:102,754,783...103,031,105
Ensembl chr 5:102,753,981...103,029,730

G

pantothenate kinase 4 (inactive)

increases expression

Selenium results in increased expression of PANK4 mRNA

NCBI chr 1:2,508,537...2,526,596
Ensembl chr 1:2,508,537...2,526,597

G

polyamine oxidase

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PAOX mRNA

NCBI chr10:133,379,262...133,391,694
Ensembl chr10:133,379,261...133,391,694

G

poly(ADP-ribose) polymerase 1

multiple interactions

[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein; AKT1 protein modified form inhibits the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]; BCL2L11 protein promotes the reaction [[Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein]

NCBI chr 1:226,360,691...226,408,093
Ensembl chr 1:226,360,210...226,408,154

G

PAX3 and PAX7 binding protein 1

decreases expression

Selenium results in decreased expression of PAXBP1 mRNA

NCBI chr21:32,733,899...32,771,755
Ensembl chr21:32,733,899...32,771,792

G

pyruvate carboxylase

increases expression

Selenium results in increased expression of PC mRNA

NCBI chr11:66,848,420...66,958,383
Ensembl chr11:66,848,417...66,958,386

G

poly(rC) binding protein 1

increases expression

Selenium results in increased expression of PCBP1 mRNA

NCBI chr 2:70,087,477...70,089,203
Ensembl chr 2:70,087,477...70,089,203

G

protocadherin gamma subfamily C, 3

increases expression

Selenium results in increased expression of PCDHGC3 mRNA

NCBI chr 5:141,475,966...141,512,975
Ensembl chr 5:141,475,947...141,512,977

G

pericentriolar material 1

decreases expression

Selenium results in decreased expression of PCM1 mRNA

NCBI chr 8:17,922,988...18,029,948
Ensembl chr 8:17,922,842...18,029,948

G

proliferating cell nuclear antigen

decreases expression

Selenium deficiency results in decreased expression of PCNA mRNA

NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626

G

procollagen C-endopeptidase enhancer

increases expression

Selenium results in increased expression of PCOLCE mRNA

NCBI chr 7:100,602,363...100,608,175
Ensembl chr 7:100,602,363...100,608,175

G

Purkinje cell protein 4

decreases expression

Selenium results in decreased expression of PCP4 mRNA

NCBI chr21:39,867,438...39,929,392
Ensembl chr21:39,867,438...39,929,397

G

proprotein convertase subtilisin/kexin type 5

decreases expression

Selenium results in decreased expression of PCSK5 mRNA

NCBI chr 9:75,889,809...76,362,975
Ensembl chr 9:75,890,644...76,362,975

G

proprotein convertase subtilisin/kexin type 7

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PCSK7 mRNA
Selenium results in increased expression of PCSK7 mRNA

NCBI chr11:117,204,337...117,232,073
Ensembl chr11:117,204,337...117,232,525

G

prenylcysteine oxidase 1 like

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PCYOX1L mRNA
Selenium results in decreased expression of PCYOX1L mRNA

NCBI chr 5:149,358,046...149,369,653
Ensembl chr 5:149,358,037...149,369,653

G

phosphodiesterase 8A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PDE8A mRNA
Selenium results in decreased expression of PDE8A mRNA

NCBI chr15:84,980,467...85,139,142
Ensembl chr15:84,980,440...85,139,145

G

platelet derived growth factor subunit A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of PDGFA mRNA

NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296

G

PDZ and LIM domain 4

increases expression

Selenium results in increased expression of PDLIM4 mRNA

NCBI chr 5:132,257,696...132,273,454
Ensembl chr 5:132,257,696...132,273,454

G

PDZ and LIM domain 7

increases expression

Selenium results in increased expression of PDLIM7 mRNA

NCBI chr 5:177,483,394...177,497,604
Ensembl chr 5:177,483,394...177,497,606

G

3-phosphoinositide dependent protein kinase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PDPK1 mRNA

NCBI chr16:2,538,021...2,603,188
Ensembl chr16:2,537,979...2,603,188

G

PDS5 cohesin associated factor B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in increased expression of APRIN mRNA
Selenium results in decreased expression of APRIN mRNA

NCBI chr13:32,586,452...32,778,019
Ensembl chr13:32,586,452...32,778,019

G

decaprenyl diphosphate synthase subunit 2

decreases expression

Selenium results in decreased expression of PDSS2 mRNA

NCBI chr 6:107,152,562...107,459,564
Ensembl chr 6:107,152,562...107,459,564

G

proliferation and apoptosis adaptor protein 15

increases expression

Selenium results in increased expression of PEA15 mRNA

NCBI chr 1:160,205,384...160,215,372
Ensembl chr 1:160,205,380...160,215,376

G

penta-EF-hand domain containing 1

increases expression

Selenium results in increased expression of PEF1 mRNA

NCBI chr 1:31,629,866...31,644,876
Ensembl chr 1:31,629,866...31,644,896

G

period circadian regulator 3

decreases expression

Selenium results in decreased expression of PER3 mRNA

NCBI chr 1:7,784,291...7,845,177
Ensembl chr 1:7,784,291...7,845,177

G

pescadillo ribosomal biogenesis factor 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PES1 mRNA
Selenium results in increased expression of PES1 mRNA

NCBI chr22:30,576,625...30,607,013
Ensembl chr22:30,576,625...30,607,083

G

peroxisomal biogenesis factor 1

decreases expression

Selenium results in decreased expression of PEX1 mRNA

NCBI chr 7:92,487,025...92,528,520
Ensembl chr 7:92,487,020...92,528,520

G

peroxisomal biogenesis factor 14

increases expression

Selenium results in increased expression of PEX14 mRNA

NCBI chr 1:10,474,950...10,630,758
Ensembl chr 1:10,472,288...10,630,758

G

peroxisomal biogenesis factor 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PEX3 mRNA
Selenium results in decreased expression of PEX3 mRNA

NCBI chr 6:143,450,805...143,490,616
Ensembl chr 6:143,450,805...143,490,616

G

peroxisomal biogenesis factor 7

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of PEX7 mRNA

NCBI chr 6:136,822,592...136,913,934
Ensembl chr 6:136,822,564...136,913,934

G

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3

increases expression

Selenium results in increased expression of PFKFB3 mRNA

NCBI chr10:6,144,921...6,326,637
Ensembl chr10:6,144,934...6,254,644

G

phosphofructokinase, liver type

increases expression

Selenium results in increased expression of PFKL mRNA

NCBI chr21:44,300,053...44,327,373
Ensembl chr21:44,300,051...44,327,376

G

profilin 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PFN1 mRNA
Selenium results in increased expression of PFN1 mRNA

NCBI chr17:4,945,652...4,948,530
Ensembl chr17:4,945,652...4,949,061

G

post-GPI attachment to proteins inositol deacylase 1

decreases expression

Selenium results in decreased expression of PGAP1 mRNA

NCBI chr 2:196,833,004...196,926,707
Ensembl chr 2:196,833,004...196,927,796

G

post-GPI attachment to proteins 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PGAP2 mRNA
Selenium results in increased expression of PGAP2 mRNA

NCBI chr11:3,797,724...3,826,371
Ensembl chr11:3,797,724...3,826,371

G

peptidoglycan recognition protein 3

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of PGLYRP3 mRNA

NCBI chr 1:153,297,116...153,312,952
Ensembl chr 1:153,297,116...153,312,952

G

phosphoglucomutase 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PGM3 mRNA
Selenium results in decreased expression of PGM3 mRNA

NCBI chr 6:83,148,705...83,193,900
Ensembl chr 6:83,147,324...83,193,936

G

phosphatase and actin regulator 2

decreases expression

Selenium results in decreased expression of PHACTR2 mRNA

NCBI chr 6:143,536,878...143,831,185
Ensembl chr 6:143,536,845...143,831,185

G

PHD finger protein 3

decreases expression

Selenium results in decreased expression of PHF3 mRNA

NCBI chr 6:63,635,802...63,726,011
Ensembl chr 6:63,635,802...63,779,336

G

pleckstrin homology like domain family A member 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PHLDA1 mRNA

NCBI chr12:76,025,447...76,031,776
Ensembl chr12:76,025,447...76,031,776

G

protein inhibitor of activated STAT 4

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PIAS4 mRNA

NCBI chr19:4,007,736...4,039,386
Ensembl chr19:4,007,736...4,039,386

G

piezo type mechanosensitive ion channel component 1 (Er blood group)

increases expression

Selenium results in increased expression of PIEZO1 mRNA

NCBI chr16:88,715,338...88,785,220
Ensembl chr16:88,715,338...88,785,220

G

phosphatidylinositol glycan anchor biosynthesis class G (EMM blood group)

decreases expression

Selenium results in decreased expression of PIGG mRNA

NCBI chr 4:499,210...540,200
Ensembl chr 4:499,210...540,200

G

phosphatidylinositol glycan anchor biosynthesis class K

decreases expression

Selenium results in decreased expression of PIGK mRNA

NCBI chr 1:77,088,989...77,219,430
Ensembl chr 1:77,088,989...77,219,430

G

phosphatidylinositol glycan anchor biosynthesis class P

decreases expression

Selenium results in decreased expression of PIGP mRNA

NCBI chr21:37,065,364...37,073,071
Ensembl chr21:37,062,846...37,073,170

G

PIH1 domain containing 1

increases expression
multiple interactions

Selenium results in increased expression of PIH1D1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of PIH1D1 mRNA

NCBI chr19:49,446,298...49,451,814
Ensembl chr19:49,446,298...49,453,497

G

phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta

increases expression
multiple interactions

Selenium results in increased expression of PIK3CD mRNA
[Selenium co-treated with Vitamin E] results in increased expression of PIK3CD mRNA

NCBI chr 1:9,627,258...9,729,114
Ensembl chr 1:9,629,889...9,729,114

G

phosphoinositide-3-kinase regulatory subunit 1

increases expression

Selenium results in increased expression of PIK3R1 mRNA

NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821

G

phosphatidylinositol transfer protein alpha

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PITPNA mRNA
Selenium results in increased expression of PITPNA mRNA

NCBI chr17:1,517,718...1,562,792
Ensembl chr17:1,517,718...1,562,792

G

phosphatidylinositol transfer protein membrane associated 1

increases expression

Selenium results in increased expression of PITPNM1 mRNA

NCBI chr11:67,491,768...67,506,266
Ensembl chr11:67,491,768...67,506,263

G

paired like homeodomain 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PITX1 mRNA
Selenium results in increased expression of PITX1 mRNA

NCBI chr 5:135,027,734...135,034,789
Ensembl chr 5:135,027,734...135,034,813

G

praja ring finger ubiquitin ligase 1

increases expression

Selenium results in increased expression of PJA1 mRNA

NCBI chr X:69,160,746...69,165,453
Ensembl chr X:69,160,851...69,165,521

G

polycystin 1, transient receptor potential channel interacting

increases expression

Selenium results in increased expression of PKD1 mRNA

NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898

G

pyruvate kinase M1/2

increases expression

Selenium results in increased expression of PKM mRNA

NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819

G

protein kinase N2

decreases expression

Selenium results in decreased expression of PKN2 mRNA

NCBI chr 1:88,684,273...88,836,255
Ensembl chr 1:88,684,222...88,836,255

G

phospholipase A2 group XIIA

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PLA2G12A mRNA
Selenium results in decreased expression of PLA2G12A mRNA

NCBI chr 4:109,709,989...109,730,070
Ensembl chr 4:109,709,989...109,730,070

G

phospholipase A and acyltransferase 3

increases expression

Selenium results in increased expression of PLAAT3 mRNA

NCBI chr11:63,574,462...63,616,927
Ensembl chr11:63,573,195...63,616,883

G

phospholipase C beta 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PLCB4 mRNA
Selenium results in decreased expression of PLCB4 mRNA

NCBI chr20:9,068,678...9,480,808
Ensembl chr20:9,067,825...9,504,593

G

plectin

increases expression

Selenium results in increased expression of PLEC mRNA

NCBI chr 8:143,915,153...143,976,745
Ensembl chr 8:143,915,153...143,976,734

G

pleckstrin homology domain containing A5

decreases expression

Selenium results in decreased expression of PLEKHA5 mRNA

NCBI chr12:19,129,733...19,376,400
Ensembl chr12:19,129,669...19,376,400

G

pleckstrin homology domain containing J1

increases expression

Selenium results in increased expression of PLEKHJ1 mRNA

NCBI chr19:2,229,981...2,236,329
Ensembl chr19:2,230,084...2,237,704

G

pleckstrin homology domain containing O1

increases expression

Selenium results in increased expression of PLEKHO1 mRNA

NCBI chr 1:150,149,646...150,160,065
Ensembl chr 1:150,149,183...150,164,720

G

plasmolipin

increases expression

Selenium results in increased expression of PLLP mRNA

NCBI chr16:57,256,097...57,284,672
Ensembl chr16:57,248,547...57,284,672

G

procollagen-lysine,2-oxoglutarate 5-dioxygenase 2

decreases expression

Selenium results in decreased expression of PLOD2 mRNA

NCBI chr 3:146,069,440...146,161,184
Ensembl chr 3:146,035,139...146,163,725

G

phospholipid phosphatase 3

decreases expression

Selenium results in decreased expression of PLPP3 mRNA

NCBI chr 1:56,494,761...56,579,563
Ensembl chr 1:56,494,761...56,645,301

G

plasmalemma vesicle associated protein

increases expression

Selenium results in increased expression of PLVAP mRNA

NCBI chr19:17,351,455...17,377,342
Ensembl chr19:17,351,450...17,377,342

G

plexin B2

increases expression

Selenium results in increased expression of PLXNB2 mRNA

NCBI chr22:50,274,979...50,307,646
Ensembl chr22:50,274,979...50,307,646

G

PML nuclear body scaffold

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PML mRNA
Selenium results in increased expression of PML mRNA

NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827

G

peptidase, mitochondrial processing subunit beta

decreases expression

Selenium results in decreased expression of PMPCB mRNA

NCBI chr 7:103,297,435...103,347,542
Ensembl chr 7:103,297,407...103,331,818

G

PMS1 homolog 1, mismatch repair system component

decreases expression

Selenium results in decreased expression of PMS1 mRNA

NCBI chr 2:189,784,450...189,877,629
Ensembl chr 2:189,784,085...189,877,629

G

PNN interacting serine and arginine rich protein

decreases expression

Selenium results in decreased expression of PNISR mRNA

NCBI chr 6:99,398,050...99,425,308
Ensembl chr 6:99,397,629...99,425,331

G

polynucleotide kinase 3'-phosphatase

increases expression

Selenium results in increased expression of PNKP mRNA

NCBI chr19:49,861,204...49,867,576
Ensembl chr19:49,859,882...49,878,351

G

patatin like phospholipase domain containing 6

increases expression

Selenium results in increased expression of PNPLA6 mRNA

NCBI chr19:7,534,164...7,561,767
Ensembl chr19:7,534,004...7,561,764

G

DNA polymerase alpha 2, accessory subunit

increases expression

Selenium results in increased expression of POLA2 mRNA

NCBI chr11:65,261,962...65,305,985
Ensembl chr11:65,261,913...65,305,959

G

DNA polymerase delta interacting protein 3

increases expression

Selenium results in increased expression of POLDIP3 mRNA

NCBI chr22:42,583,721...42,614,883
Ensembl chr22:42,583,721...42,614,962

G

DNA polymerase lambda

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of POLL mRNA
Selenium results in increased expression of POLL mRNA

NCBI chr10:101,578,882...101,588,270
Ensembl chr10:101,578,882...101,588,270

G

RNA polymerase II subunit A

increases expression

Selenium results in increased expression of POLR2A mRNA

NCBI chr17:7,484,366...7,514,616
Ensembl chr17:7,484,366...7,514,616

G

RNA polymerase II subunit C

increases expression

Selenium results in increased expression of POLR2C mRNA

NCBI chr16:57,462,679...57,472,009
Ensembl chr16:57,462,660...57,472,009

G

RNA polymerase II, I and III subunit K

decreases expression

Selenium results in decreased expression of POLR2K mRNA

NCBI chr 8:100,150,636...100,154,003
Ensembl chr 8:100,150,623...100,154,003

G

RNA polymerase II subunit M

decreases expression

Selenium results in decreased expression of POLR2M mRNA

NCBI chr15:57,706,714...57,717,557
Ensembl chr15:57,706,695...57,782,762

G

paraoxonase 1

multiple interactions

Selenium inhibits the reaction [Mercury results in decreased activity of PON1 protein]; Selenium inhibits the reaction [Methylmercury Compounds results in decreased activity of PON1 protein]

NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532

G

paraoxonase 2

decreases expression

Selenium results in decreased expression of PON2 mRNA

NCBI chr 7:95,404,862...95,435,028
Ensembl chr 7:95,404,862...95,435,329

G

cytochrome p450 oxidoreductase

increases expression

Selenium results in increased expression of POR mRNA

NCBI chr 7:75,915,155...75,986,855
Ensembl chr 7:75,899,200...75,986,855

G

periostin

decreases expression

Selenium results in decreased expression of POSTN mRNA

NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844

G

peroxisome proliferator activated receptor alpha

increases expression

Selenium results in increased expression of PPARA mRNA

NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755

G

peroxisome proliferator activated receptor gamma

multiple interactions

PPARG protein promotes the reaction [Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]]; Selenium promotes the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased activity of PPARG protein]

NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356

G

PPARG coactivator 1 alpha

decreases expression

Selenium results in decreased expression of PPARGC1A mRNA

NCBI chr 4:23,792,021...24,472,905
Ensembl chr 4:23,755,041...23,904,089

G

phosphoribosyl pyrophosphate amidotransferase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PPAT mRNA
Selenium results in decreased expression of PPAT mRNA

NCBI chr 4:56,393,362...56,435,615
Ensembl chr 4:56,393,362...56,435,615

G

PPFIA binding protein 1

decreases expression

Selenium results in decreased expression of PPFIBP1 mRNA

NCBI chr12:27,524,206...27,695,564
Ensembl chr12:27,523,431...27,695,564

G

peptidylprolyl isomerase B

increases expression

Selenium results in increased expression of PPIB mRNA

NCBI chr15:64,155,817...64,163,022
Ensembl chr15:64,155,740...64,163,134

G

peptidylprolyl isomerase G

decreases expression

Selenium results in decreased expression of PPIG mRNA

NCBI chr 2:169,584,351...169,641,406
Ensembl chr 2:169,584,342...169,641,406

G

peptidylprolyl isomerase like 2

increases expression

Selenium results in increased expression of PPIL2 mRNA

NCBI chr22:21,666,012...21,700,015
Ensembl chr22:21,666,000...21,700,015

G

protein phosphatase, Mg2+/Mn2+ dependent 1J

increases expression

Selenium results in increased expression of PPM1J mRNA

NCBI chr 1:112,709,998...112,715,332
Ensembl chr 1:112,709,994...112,715,332

G

protein phosphatase methylesterase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PPME1 mRNA
Selenium results in increased expression of PPME1 mRNA

NCBI chr11:74,171,289...74,254,703
Ensembl chr11:74,171,267...74,254,703

G

protein phosphatase 1 catalytic subunit alpha

increases expression

Selenium results in increased expression of PPP1CA mRNA

NCBI chr11:67,398,183...67,401,858
Ensembl chr11:67,398,181...67,421,183

G

protein phosphatase 1 regulatory subunit 10

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PPP1R10 mRNA
Selenium results in increased expression of PPP1R10 mRNA

NCBI chr 6:30,600,413...30,617,243
Ensembl chr 6:30,600,413...30,618,612

G

protein phosphatase 1 regulatory inhibitor subunit 14B

increases expression

Selenium results in increased expression of PPP1R14B mRNA

NCBI chr11:64,244,479...64,246,943
Ensembl chr11:64,244,479...64,246,943

G

protein phosphatase 1 regulatory subunit 9A

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PPP1R9A mRNA
Selenium results in decreased expression of PPP1R9A mRNA

NCBI chr 7:94,907,236...95,296,415
Ensembl chr 7:94,907,202...95,296,415

G

protein phosphatase 2 scaffold subunit Aalpha

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PPP2R1A mRNA
Selenium results in increased expression of PPP2R1A mRNA

NCBI chr19:52,190,052...52,229,518
Ensembl chr19:52,170,936...52,229,518

G

protein phosphatase 2 regulatory subunit B'delta

increases expression

Selenium results in increased expression of PPP2R5D mRNA

NCBI chr 6:42,984,570...43,012,342
Ensembl chr 6:42,984,553...43,012,342

G

protein phosphatase 2 regulatory subunit B'epsilon

decreases expression

Selenium results in decreased expression of PPP2R5E mRNA

NCBI chr14:63,371,364...63,543,377
Ensembl chr14:63,371,364...63,543,377

G

protein phosphatase 4 catalytic subunit

increases expression

Selenium results in increased expression of PPP4C mRNA

NCBI chr16:30,075,994...30,085,376
Ensembl chr16:30,075,978...30,085,376

G

protein phosphatase 6 regulatory subunit 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PPP6R2 mRNA
Selenium results in increased expression of PPP6R2 mRNA

NCBI chr22:50,330,774...50,445,090
Ensembl chr22:50,343,304...50,445,090

G

PRA1 domain family member 2

increases expression

Selenium results in increased expression of PRAF2 mRNA

NCBI chr X:49,071,161...49,074,002
Ensembl chr X:49,071,161...49,074,002

G

PR/SET domain 2

increases expression

Selenium results in increased expression of PRDM2 mRNA

NCBI chr 1:13,700,188...13,825,079
Ensembl chr 1:13,700,188...13,825,079

G

peroxiredoxin 2

decreases expression

Selenium deficiency results in decreased expression of PRDX2 mRNA

NCBI chr19:12,796,823...12,801,800
Ensembl chr19:12,796,820...12,801,800

G

prickle planar cell polarity protein 2

decreases methylation

Selenium results in decreased methylation of PRICKLE2 gene

NCBI chr 3:64,092,236...64,268,173
Ensembl chr 3:64,092,236...64,445,476

G

protein kinase AMP-activated non-catalytic subunit gamma 1

increases expression

Selenium results in increased expression of PRKAG1 mRNA

NCBI chr12:49,002,274...49,018,776
Ensembl chr12:49,002,274...49,018,807

G

protein kinase C beta

decreases expression

Selenium results in decreased expression of PRKCB mRNA

NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611

G

protein kinase C iota

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PRKCI mRNA
Selenium results in decreased expression of PRKCI mRNA

NCBI chr 3:170,222,424...170,305,977
Ensembl chr 3:170,222,424...170,305,977

G

protein kinase D2

increases expression

Selenium results in increased expression of PRKD2 mRNA

NCBI chr19:46,674,316...46,717,114
Ensembl chr19:46,674,275...46,717,127

G

protein arginine methyltransferase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PRMT1 mRNA
Selenium results in increased expression of PRMT1 mRNA

NCBI chr19:49,676,153...49,688,447
Ensembl chr19:49,675,786...49,689,029

G

protein arginine methyltransferase 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PRMT2 mRNA
Selenium results in increased expression of PRMT2 mRNA

NCBI chr21:46,635,674...46,665,124
Ensembl chr21:46,635,595...46,665,124

G

protein arginine methyltransferase 3

decreases expression

Selenium results in decreased expression of PRMT3 mRNA

NCBI chr11:20,387,716...20,509,338
Ensembl chr11:20,387,558...20,509,338

G

protein arginine methyltransferase 5

increases expression

Selenium results in increased expression of PRMT5 mRNA

NCBI chr14:22,920,529...22,929,376
Ensembl chr14:22,920,525...22,929,408

G

protein C, inactivator of coagulation factors Va and VIIIa

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of PROC mRNA

NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242

G

pre-mRNA processing factor kinase PRP4K

decreases expression

Selenium results in decreased expression of PRP4K mRNA

NCBI chr 6:4,021,300...4,064,983
Ensembl chr 6:4,021,267...4,064,983

G

pre-mRNA processing factor 40 homolog A

decreases expression

Selenium results in decreased expression of PRPF40A mRNA

NCBI chr 2:152,651,732...152,718,019
Ensembl chr 2:152,651,593...152,718,012

G

pre-mRNA processing factor 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PRPF6 mRNA
Selenium results in increased expression of PRPF6 mRNA

NCBI chr20:63,981,132...64,033,100
Ensembl chr20:63,981,132...64,033,100

G

pre-mRNA processing factor 8

increases expression

Selenium results in increased expression of PRPF8 mRNA

NCBI chr17:1,650,629...1,684,867
Ensembl chr17:1,650,629...1,684,867

G

proline rich coiled-coil 2C

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PRRC2C mRNA
Selenium results in decreased expression of PRRC2C mRNA

NCBI chr 1:171,485,530...171,593,511
Ensembl chr 1:171,485,530...171,593,511

G

serine protease 8

increases expression

Selenium results in increased expression of PRSS8 mRNA

NCBI chr16:31,131,433...31,135,727
Ensembl chr16:31,131,433...31,135,727

G

prune exopolyphosphatase 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of PRUNE1 mRNA

NCBI chr 1:151,008,449...151,035,713
Ensembl chr 1:151,008,420...151,035,713

G

periaxin

increases expression

Selenium results in increased expression of PRX mRNA

NCBI chr19:40,393,764...40,414,789
Ensembl chr19:40,393,766...40,414,793

G

prosaposin

increases expression

Selenium results in increased expression of PSAP mRNA

NCBI chr10:71,816,298...71,851,251
Ensembl chr10:71,816,298...71,851,251

G

PC4 and SRSF1 interacting protein 1

decreases expression

Selenium results in decreased expression of PSIP1 mRNA

NCBI chr 9:15,464,066...15,510,970
Ensembl chr 9:15,464,066...15,510,995

G

proteasome 20S subunit beta 10

increases expression

Selenium results in increased expression of PSMB10 mRNA

NCBI chr16:67,934,506...67,936,850
Ensembl chr16:67,934,506...67,936,864

G

proteasome 20S subunit beta 4

increases expression

Selenium results in increased expression of PSMB4 mRNA

NCBI chr 1:151,399,573...151,401,937
Ensembl chr 1:151,399,560...151,401,937

G

proteasome 26S subunit, ATPase 1

increases expression

Selenium results in increased expression of PSMC1 mRNA

NCBI chr14:90,256,553...90,275,429
Ensembl chr14:90,256,527...90,275,429

G

proteasome 26S subunit, ATPase 4

increases expression

Selenium results in increased expression of PSMC4 mRNA

NCBI chr19:39,971,165...39,981,764
Ensembl chr19:39,971,165...39,981,764

G

proteasome 26S subunit ubiquitin receptor, non-ATPase 4

increases expression

Selenium results in increased expression of PSMD4 mRNA

NCBI chr 1:151,254,734...151,267,479
Ensembl chr 1:151,254,709...151,267,479

G

proteasome 26S subunit, non-ATPase 6

increases expression

Selenium results in increased expression of PSMD6 mRNA

NCBI chr 3:64,010,551...64,024,007
Ensembl chr 3:64,010,550...64,024,010

G

proteasome 26S subunit, non-ATPase 8

increases expression

Selenium results in increased expression of PSMD8 mRNA

NCBI chr19:38,374,571...38,383,824
Ensembl chr19:38,374,563...38,383,850

G

proteasome activator subunit 1

increases expression

Selenium results in increased expression of PSME1 mRNA

NCBI chr14:24,136,194...24,138,962
Ensembl chr14:24,136,163...24,138,967

G

platelet activating factor receptor

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of PTAFR mRNA

NCBI chr 1:28,147,166...28,193,856
Ensembl chr 1:28,147,166...28,193,936

G

prostaglandin D2 synthase

increases expression

Selenium results in increased expression of PTGDS mRNA

NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742

G

prostaglandin E synthase

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PTGES mRNA
[Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of PTGES mRNA; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of PTGES protein
Selenium results in increased expression of PTGES mRNA

PMID:19244175 PMID:21669866

NCBI chr 9:129,738,349...129,753,042
Ensembl chr 9:129,738,331...129,753,042

G

prostaglandin reductase 1

affects expression

Selenium affects the expression of PTGR1 protein

NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893

G

prostaglandin-endoperoxide synthase 2

multiple interactions

PPARG protein promotes the reaction [Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]]; Selenium deficiency promotes the reaction [[Lipopolysaccharides results in increased expression of PTGS2 protein] which results in increased chemical synthesis of Dinoprostone]; Selenium deficiency promotes the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Selenium inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [bisphenol A results in increased expression of PTGS2 mRNA]; [Vitamin E co-treated with Selenium] results in decreased expression of PTGS2 mRNA; [Vitamin E co-treated with Selenium] results in decreased expression of PTGS2 protein

PMID:11978490 PMID:17439952 PMID:22223226 PMID:30526071

NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922

G

parathymosin

increases expression

Selenium results in increased expression of PTMS mRNA

NCBI chr12:6,766,363...6,770,952
Ensembl chr12:6,765,516...6,770,952

G

PTOV1 extended AT-hook containing adaptor protein

increases expression

Selenium results in increased expression of PTOV1 mRNA

NCBI chr19:49,850,705...49,860,742
Ensembl chr19:49,850,735...49,860,744

G

protein phosphatase 2 phosphatase activator

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PTPA mRNA
Selenium results in increased expression of PTPA mRNA

NCBI chr 9:129,110,950...129,148,946
Ensembl chr 9:129,110,950...129,148,946

G

protein tyrosine phosphatase non-receptor type 1

increases expression
multiple interactions
decreases glutathionylation

Selenium results in increased expression of PTPN1 protein
Selenium inhibits the reaction [Potassium Iodide results in decreased expression of PTPN1 mRNA]
Selenium results in decreased glutathionylation of PTPN1 protein

PMID:19022953 PMID:38013145

NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241

G

protein tyrosine phosphatase non-receptor type 18

increases expression

Selenium results in increased expression of PTPN18 mRNA

NCBI chr 2:130,356,056...130,375,405
Ensembl chr 2:130,356,045...130,375,405

G

protein tyrosine phosphatase non-receptor type 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of PTPN6 mRNA
Selenium results in increased expression of PTPN6 mRNA

NCBI chr12:6,946,577...6,961,316
Ensembl chr12:6,946,468...6,961,316

G

protein tyrosine phosphatase receptor type O

decreases expression

Selenium results in decreased expression of PTPRO mRNA

NCBI chr12:15,322,508...15,598,331
Ensembl chr12:15,322,257...15,602,175

G

pentraxin 3

increases expression

Selenium results in increased expression of PTX3 mRNA

NCBI chr 3:157,436,850...157,443,633
Ensembl chr 3:157,436,850...157,443,633

G

poly(U) binding splicing factor 60

increases expression

Selenium results in increased expression of PUF60 mRNA

NCBI chr 8:143,816,344...143,829,315
Ensembl chr 8:143,816,344...143,830,709

G

PWP1 homolog, endonuclein

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of PWP1 mRNA
Selenium results in decreased expression of PWP1 mRNA

NCBI chr12:107,685,799...107,713,162
Ensembl chr12:107,685,799...107,713,162

G

PYD and CARD domain containing

increases expression

Selenium results in increased expression of PYCARD mRNA

NCBI chr16:31,201,486...31,202,760
Ensembl chr16:31,201,486...31,203,450

G

pyrroline-5-carboxylate reductase 3

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of PYCR3 mRNA

NCBI chr 8:143,603,210...143,609,575
Ensembl chr 8:143,603,210...143,609,773

G

glycogen phosphorylase B

increases expression

Selenium results in increased expression of PYGB mRNA

NCBI chr20:25,248,085...25,298,012
Ensembl chr20:25,248,085...25,298,012

G

queuine tRNA-ribosyltransferase catalytic subunit 1

increases expression
multiple interactions

Selenium results in increased expression of QTRT1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of QTRT1 mRNA

NCBI chr19:10,701,439...10,713,365
Ensembl chr19:10,701,430...10,713,437

G

R3H domain containing 1

decreases expression

Selenium results in decreased expression of R3HDM1 mRNA

NCBI chr 2:135,531,484...135,725,269
Ensembl chr 2:135,531,455...135,725,270

G

RAB11B, member RAS oncogene family

increases expression

Selenium results in increased expression of RAB11B mRNA

NCBI chr19:8,390,360...8,404,434
Ensembl chr19:8,389,981...8,404,434

G

RAB14, member RAS oncogene family

decreases expression

Selenium results in decreased expression of RAB14 mRNA

NCBI chr 9:121,178,133...121,201,869
Ensembl chr 9:121,178,133...121,223,014

G

RAB25, member RAS oncogene family

increases expression

Selenium results in increased expression of RAB25 mRNA

NCBI chr 1:156,061,160...156,070,504
Ensembl chr 1:156,061,160...156,070,504

G

RAB2A, member RAS oncogene family

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RAB2 mRNA
Selenium results in increased expression of RAB2 mRNA

NCBI chr 8:60,516,910...60,623,644
Ensembl chr 8:60,516,936...60,623,644

G

Rab acceptor 1

increases expression

Selenium results in increased expression of RABAC1 mRNA

NCBI chr19:41,956,683...41,959,321
Ensembl chr19:41,956,681...41,959,321

G

RAB GTPase activating protein 1

decreases expression

Selenium results in decreased expression of RABGAP1 mRNA

NCBI chr 9:122,931,671...123,104,866
Ensembl chr 9:122,940,833...123,104,866

G

RAD23 homolog A, nucleotide excision repair protein

increases expression

Selenium results in increased expression of RAD23A mRNA

NCBI chr19:12,945,862...12,953,642
Ensembl chr19:12,945,855...12,953,642

G

RAD23 homolog B, nucleotide excision repair protein

decreases expression

Selenium results in decreased expression of RAD23B mRNA

NCBI chr 9:107,283,279...107,332,194
Ensembl chr 9:107,283,137...107,332,192

G

ralA binding protein 1

decreases expression
multiple interactions

Selenium results in decreased expression of RALBP1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of RALBP1 mRNA

NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114

G

Ral GEF with PH domain and SH3 binding motif 1

decreases expression

Selenium results in decreased expression of RALGPS1 mRNA

NCBI chr 9:126,914,782...127,223,166
Ensembl chr 9:126,914,774...127,223,166

G

RALY heterogeneous nuclear ribonucleoprotein

increases expression

Selenium results in increased expression of RALY mRNA

NCBI chr20:33,993,911...34,084,884
Ensembl chr20:33,993,646...34,108,308

G

RAN binding protein 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RANBP2 mRNA
Selenium results in decreased expression of RANBP2 mRNA

NCBI chr 2:108,719,482...109,842,301
Ensembl chr 2:108,719,482...108,785,810

G

RAN binding protein 3

increases expression

Selenium results in increased expression of RANBP3 mRNA

NCBI chr19:5,916,139...5,978,140
Ensembl chr19:5,916,139...5,978,142

G

RAN binding protein 9

decreases expression

Selenium results in decreased expression of RANBP9 mRNA

NCBI chr 6:13,621,498...13,711,835
Ensembl chr 6:13,621,498...13,711,835

G

Ran GTPase activating protein 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of RANGAP1 mRNA
Selenium results in increased expression of RANGAP1 mRNA

NCBI chr22:41,244,779...41,302,369
Ensembl chr22:41,244,779...41,286,187

G

Rap guanine nucleotide exchange factor 6

decreases expression

Selenium results in decreased expression of RAPGEF6 mRNA

NCBI chr 5:131,423,921...131,635,229
Ensembl chr 5:131,423,921...131,635,231

G

Ras association domain family member 1

increases expression

Selenium results in increased expression of RASSF1 mRNA

NCBI chr 3:50,329,788...50,340,836
Ensembl chr 3:50,329,782...50,340,980

G

Ras association domain family member 7

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of RASSF7 mRNA

NCBI chr11:560,970...564,025
Ensembl chr11:560,404...564,025

G

RB binding protein 4, chromatin remodeling factor

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of RBBP4 mRNA

NCBI chr 1:32,651,208...32,686,211
Ensembl chr 1:32,651,142...32,686,211

G

RB binding protein 6, ubiquitin ligase

decreases expression
multiple interactions

Selenium results in decreased expression of RBBP6 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of RBBP6 mRNA

NCBI chr16:24,539,566...24,572,863
Ensembl chr16:24,537,693...24,572,863

G

RANBP2-type and C3HC4-type zinc finger containing 1

increases expression

Selenium results in increased expression of RBCK1 mRNA

NCBI chr20:408,299...432,139
Ensembl chr20:407,498...432,139

G

RNA binding motif protein 10

increases expression

Selenium results in increased expression of RBM10 mRNA

NCBI chr X:47,145,221...47,186,813
Ensembl chr X:47,145,221...47,186,813

G

RNA binding motif protein 14

increases expression

Selenium results in increased expression of RBM14 mRNA

NCBI chr11:66,616,630...66,629,934
Ensembl chr11:66,616,626...66,629,934

G

RNA binding motif protein 25

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RBM25 mRNA
Selenium results in decreased expression of RBM25 mRNA

NCBI chr14:73,058,534...73,123,899
Ensembl chr14:73,058,532...73,123,899

G

RNA binding motif protein 4

decreases expression

Selenium results in decreased expression of RBM4 mRNA

NCBI chr11:66,638,703...66,668,380
Ensembl chr11:66,638,667...66,668,374

G

RNA binding motif protein 42

increases expression

Selenium results in increased expression of RBM42 mRNA

NCBI chr19:35,629,036...35,637,685
Ensembl chr19:35,629,030...35,637,686

G

RNA binding motif protein 5

increases expression

Selenium results in increased expression of RBM5 mRNA

NCBI chr 3:50,088,919...50,119,021
Ensembl chr 3:50,088,919...50,119,021

G

RNA binding motif single stranded interacting protein 1

decreases expression
increases expression

Selenium results in decreased expression of RBMS1 mRNA
Selenium results in increased expression of RBMS1 mRNA

NCBI chr 2:160,272,151...160,493,807
Ensembl chr 2:160,272,151...160,493,807

G

RNA binding protein, mRNA processing factor

increases expression

Selenium results in increased expression of RBPMS mRNA

NCBI chr 8:30,384,541...30,572,256
Ensembl chr 8:30,384,511...30,572,256

G

ring finger and CHY zinc finger domain containing 1

decreases expression

Selenium results in decreased expression of RCHY1 mRNA

NCBI chr 4:75,479,033...75,514,715
Ensembl chr 4:75,479,033...75,514,764

G

REST corepressor 3

decreases expression

Selenium results in decreased expression of RCOR3 mRNA

NCBI chr 1:211,259,366...211,316,385
Ensembl chr 1:211,258,377...211,316,385

G

retinol dehydrogenase 11

decreases expression

Selenium results in decreased expression of RDH11 mRNA

NCBI chr14:67,676,800...67,695,764
Ensembl chr14:67,676,800...67,695,793

G

reversion inducing cysteine rich protein with kazal motifs

decreases expression

Selenium results in decreased expression of RECK mRNA

NCBI chr 9:36,036,913...36,124,455
Ensembl chr 9:36,036,913...36,124,455

G

RecQ like helicase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RECQL mRNA
Selenium results in decreased expression of RECQL mRNA

NCBI chr12:21,468,910...21,501,635
Ensembl chr12:21,468,910...21,501,669

G

RecQ like helicase 5

increases expression

Selenium results in increased expression of RECQL5 mRNA

NCBI chr17:75,626,854...75,667,154
Ensembl chr17:75,626,845...75,667,189

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases expression

Selenium inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]
[Vitamin E co-treated with Selenium] results in decreased activity of RELA protein; Selenium inhibits the reaction [arsenite results in decreased expression of RELA protein]
[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of RELA protein
Selenium results in increased expression of RELA mRNA

PMID:14734799 PMID:19244175 PMID:21481475 PMID:22223226 PMID:29324385

NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090

G

reticulophagy regulator family member 2

increases expression

Selenium results in increased expression of RETREG2 mRNA

NCBI chr 2:219,178,275...219,185,475
Ensembl chr 2:219,176,225...219,185,475

G

raftlin, lipid raft linker 1

increases expression

Selenium results in increased expression of RFTN1 mRNA

NCBI chr 3:16,315,845...16,513,699
Ensembl chr 3:16,313,574...16,514,026

G

RANBP2 like and GRIP domain containing 8

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RGPD8 mRNA
Selenium results in decreased expression of RGPD8 mRNA

NCBI chr 2:112,368,369...112,433,645
Ensembl chr 2:112,368,369...112,434,488
Ensembl chr 2:112,368,369...112,434,488

G

rhomboid domain containing 3

increases expression

Selenium results in increased expression of RHBDD3 mRNA

NCBI chr22:29,259,852...29,268,163
Ensembl chr22:29,259,872...29,268,209

G

Rho related BTB domain containing 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RHOBTB1 mRNA
Selenium results in decreased expression of RHOBTB1 mRNA

NCBI chr10:60,860,860...61,001,967
Ensembl chr10:60,869,438...61,001,440

G

Rho related BTB domain containing 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RHOBTB3 mRNA
Selenium results in decreased expression of RHOBTB3 mRNA

NCBI chr 5:95,717,624...95,796,361
Ensembl chr 5:95,713,522...95,824,383

G

ras homolog family member G

increases expression

Selenium results in increased expression of RHOG mRNA

NCBI chr11:3,826,978...3,840,959
Ensembl chr11:3,826,978...3,840,959

G

ring finger protein 1

increases expression

Selenium results in increased expression of RING1 mRNA

NCBI chr 6:33,208,500...33,212,716
Ensembl chr 6:33,208,500...33,212,722

G

ribonuclease H1

decreases expression

Selenium results in decreased expression of RNASEH1 mRNA

NCBI chr 2:3,531,813...3,558,333
Ensembl chr 2:3,541,430...3,558,333

G

Rho family GTPase 1

increases expression

Selenium results in increased expression of RND1 mRNA

NCBI chr12:48,857,145...48,865,870
Ensembl chr12:48,857,145...48,865,870

G

Rho family GTPase 3

decreases expression

Selenium results in decreased expression of RND3 mRNA

NCBI chr 2:150,468,193...150,487,695
Ensembl chr 2:150,468,195...150,539,011

G

ring finger protein 111

decreases expression

Selenium results in decreased expression of RNF111 mRNA

NCBI chr15:58,987,663...59,097,419
Ensembl chr15:58,865,175...59,097,419

G

ring finger protein 114

increases expression

Selenium results in increased expression of RNF114 mRNA

NCBI chr20:49,936,397...49,953,885
Ensembl chr20:49,936,336...49,953,885

G

ring finger protein 220

increases expression

Selenium results in increased expression of RNF220 mRNA

NCBI chr 1:44,404,783...44,651,724
Ensembl chr 1:44,405,194...44,651,723

G

ring finger protein 40

increases expression

Selenium results in increased expression of RNF40 mRNA

NCBI chr16:30,761,612...30,776,307
Ensembl chr16:30,761,745...30,776,307

G

ribonuclease/angiogenin inhibitor 1

increases expression

Selenium results in increased expression of RNH1 mRNA

NCBI chr11:494,515...507,242
Ensembl chr11:494,512...507,300

G

arginyl aminopeptidase

increases expression

Selenium results in increased expression of RNPEP mRNA

NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147

G

RNA binding protein with serine rich domain 1

increases expression

Selenium results in increased expression of RNPS1 mRNA

NCBI chr16:2,253,116...2,268,126
Ensembl chr16:2,253,116...2,268,397

G

Ro60, Y RNA binding protein

decreases expression

Selenium results in decreased expression of RO60 mRNA

NCBI chr 1:193,059,612...193,091,777
Ensembl chr 1:193,059,454...193,091,777

G

ribosomal protein L10a

decreases expression

Selenium results in decreased expression of RPL10A mRNA

NCBI chr 6:35,468,401...35,470,780
Ensembl chr 6:35,468,401...35,470,785

G

ribosomal protein L14

decreases expression

Selenium results in decreased expression of RPL14 mRNA

NCBI chr 3:40,457,339...40,468,587
Ensembl chr 3:40,457,292...40,468,587

G

ribosomal protein L23

decreases expression

Selenium results in decreased expression of RPL23 mRNA

NCBI chr17:38,847,860...38,853,721
Ensembl chr17:38,847,860...38,853,764

G

ribosomal protein L27

decreases expression

Selenium results in decreased expression of RPL27 mRNA

NCBI chr17:42,998,273...43,002,959
Ensembl chr17:42,998,273...43,002,959

G

ribosomal protein L31

decreases expression

Selenium results in decreased expression of RPL31 mRNA

NCBI chr 2:101,002,289...101,019,724
Ensembl chr 2:101,002,229...101,024,032

G

ribosomal protein L37a

decreases expression

Selenium results in decreased expression of RPL37A mRNA

NCBI chr 2:216,498,844...216,504,086
Ensembl chr 2:216,498,825...216,579,180

G

ribosomal protein L38

decreases expression

Selenium results in decreased expression of RPL38 mRNA

NCBI chr17:74,203,678...74,210,655
Ensembl chr17:74,203,582...74,210,655

G

ribosomal protein L39

decreases expression

Selenium results in decreased expression of RPL39 mRNA

NCBI chr X:119,786,504...119,791,630
Ensembl chr X:119,786,504...119,791,630

G

ribosomal protein L7

decreases expression

Selenium results in decreased expression of RPL7 mRNA

NCBI chr 8:73,290,242...73,294,466
Ensembl chr 8:73,290,242...73,295,789

G

regulation of nuclear pre-mRNA domain containing 2

increases expression

Selenium results in increased expression of RPRD2 mRNA

NCBI chr 1:150,364,147...150,476,566
Ensembl chr 1:150,363,091...150,476,566

G

ribosomal protein S20

decreases expression

Selenium results in decreased expression of RPS20 mRNA

NCBI chr 8:56,067,254...56,074,506
Ensembl chr 8:56,067,254...56,074,510

G

ribosomal protein S21

decreases expression

Selenium results in decreased expression of RPS21 mRNA

NCBI chr20:62,387,103...62,388,520
Ensembl chr20:62,387,103...62,388,520

G

ribosomal protein S25

decreases expression

Selenium results in decreased expression of RPS25 mRNA

NCBI chr11:119,015,717...119,018,343
Ensembl chr11:119,015,712...119,018,691

G

ribosomal protein S27

decreases expression

Selenium results in decreased expression of RPS27 mRNA

NCBI chr 1:153,990,762...153,992,155
Ensembl chr 1:153,990,762...153,992,155

G

ribosomal protein S27 like

decreases expression

Selenium results in decreased expression of RPS27L mRNA

NCBI chr15:63,148,249...63,157,477
Ensembl chr15:63,125,872...63,158,021

G

ribosomal protein S29

decreases expression

Selenium results in decreased expression of RPS29 mRNA

NCBI chr14:49,570,988...49,598,710
Ensembl chr14:49,570,984...49,599,164

G

ribosomal protein S6 kinase A1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of RPS6KA1 mRNA
Selenium results in increased expression of RPS6KA1 mRNA

NCBI chr 1:26,529,761...26,575,025
Ensembl chr 1:26,529,761...26,575,030

G

ribosomal protein S6 kinase A2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of RPS6KA2 mRNA
Selenium results in increased expression of RPS6KA2 mRNA

NCBI chr 6:166,409,364...166,862,773
Ensembl chr 6:166,409,364...166,906,451

G

ribosomal protein S7

decreases expression

Selenium results in decreased expression of RPS7 mRNA

NCBI chr 2:3,575,260...3,580,920
Ensembl chr 2:3,575,260...3,580,920

G

ribosome binding protein 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of RRBP1 mRNA

NCBI chr20:17,613,679...17,682,242
Ensembl chr20:17,613,678...17,682,295

G

ribosomal RNA processing 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of RRP1 mRNA
Selenium results in increased expression of RRP1 mRNA

NCBI chr21:43,789,577...43,805,293
Ensembl chr21:43,789,513...43,805,293

G

ribosomal RNA processing 7 homolog A

increases expression

Selenium results in increased expression of RRP7A mRNA

NCBI chr22:42,508,344...42,519,796
Ensembl chr22:42,508,344...42,519,796

G

radical S-adenosyl methionine domain containing 1

increases expression

Selenium results in increased expression of RSAD1 mRNA

NCBI chr17:50,478,860...50,485,974
Ensembl chr17:50,478,860...50,485,974

G

arginine and serine rich coiled-coil 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RSRC2 mRNA
Selenium results in decreased expression of RSRC2 mRNA

NCBI chr12:122,503,454...122,526,936
Ensembl chr12:122,503,454...122,527,000

G

arginine and serine rich protein 1

decreases expression

Selenium results in decreased expression of RSRP1 mRNA

NCBI chr 1:25,242,249...25,338,254
Ensembl chr 1:25,242,249...25,338,213

G

retrotransposon Gag like 8A

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of RTL8A mRNA

NCBI chr X:135,050,932...135,052,135
Ensembl chr X:135,050,932...135,052,196

G

RUN and FYVE domain containing 3

decreases expression

Selenium results in decreased expression of RUFY3 mRNA

NCBI chr 4:70,703,767...70,808,619
Ensembl chr 4:70,704,204...70,808,619

G

RUNX1 partner transcriptional co-repressor 1

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of RUNX1T1 mRNA

NCBI chr 8:91,954,967...92,103,385
Ensembl chr 8:91,954,972...92,103,385

G

RUN and SH3 domain containing 2

increases expression

Selenium results in increased expression of RUSC2 mRNA

NCBI chr 9:35,490,111...35,561,895
Ensembl chr 9:35,490,111...35,561,898

G

RuvB like AAA ATPase 1

increases expression

Selenium results in increased expression of RUVBL1 mRNA

NCBI chr 3:128,064,785...128,153,914
Ensembl chr 3:128,064,778...128,153,914

G

RuvB like AAA ATPase 2

increases expression

Selenium results in increased expression of RUVBL2 mRNA

NCBI chr19:48,993,448...49,015,995
Ensembl chr19:48,993,562...49,015,970

G

retinoid X receptor alpha

increases expression

Selenium results in increased expression of RXRA protein

NCBI chr 9:134,326,455...134,440,585
Ensembl chr 9:134,317,098...134,440,585

G

RING1 and YY1 binding protein

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of RYBP mRNA
Selenium results in decreased expression of RYBP mRNA

NCBI chr 3:72,374,597...72,446,623
Ensembl chr 3:72,371,825...72,446,621

G

S100 calcium binding protein A11

increases expression

Selenium results in increased expression of S100A11 mRNA

NCBI chr 1:152,032,506...152,037,004
Ensembl chr 1:152,032,506...152,047,907

G

S100 calcium binding protein A6

increases expression

Selenium results in increased expression of S100A6 mRNA

NCBI chr 1:153,534,599...153,535,991
Ensembl chr 1:153,534,599...153,536,244

G

sacsin molecular chaperone

decreases expression

Selenium results in decreased expression of SACS mRNA

NCBI chr13:23,328,830...23,433,702
Ensembl chr13:23,288,689...23,433,763

G

scaffold attachment factor B

increases expression

Selenium results in increased expression of SAFB mRNA

NCBI chr19:5,623,083...5,668,478
Ensembl chr19:5,623,035...5,668,478

G

scaffold attachment factor B2

increases expression

Selenium results in increased expression of SAFB2 mRNA

NCBI chr19:5,586,999...5,622,776
Ensembl chr19:5,586,999...5,624,046

G

SAMM50 sorting and assembly machinery component

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SAMM50 mRNA

NCBI chr22:43,955,442...43,996,529
Ensembl chr22:43,955,442...44,010,531

G

secretion associated Ras related GTPase 1B

decreases expression

Selenium results in decreased expression of SAR1B mRNA

NCBI chr 5:134,601,149...134,632,828
Ensembl chr 5:134,601,149...134,649,271

G

sarcosine dehydrogenase

increases expression

Selenium results in increased expression of SARDH mRNA

NCBI chr 9:133,659,418...133,739,955
Ensembl chr 9:133,663,560...133,739,955

G

spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP

increases expression

Selenium results in increased expression of SART1 mRNA

NCBI chr11:65,961,734...65,980,137
Ensembl chr11:65,961,728...65,980,137

G

spliceosome associated factor 3, U4/U6 recycling protein

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SART3 mRNA

NCBI chr12:108,522,214...108,561,173
Ensembl chr12:108,522,214...108,561,400

G

spermidine/spermine N1-acetyltransferase 1

decreases expression

Selenium results in decreased expression of SAT1 mRNA

NCBI chr X:23,783,173...23,786,210
Ensembl chr X:23,783,173...23,786,210

G

SATB homeobox 1

decreases expression

Selenium results in decreased expression of SATB1 mRNA

NCBI chr 3:18,345,377...18,445,592
Ensembl chr 3:18,345,377...18,445,621

G

SR-related CTD associated factor 11

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SCAF11 mRNA

NCBI chr12:45,919,131...45,992,059
Ensembl chr12:45,919,131...45,992,120

G

SR-related CTD associated factor 4

decreases expression

Selenium results in decreased expression of SCAF4 mRNA

NCBI chr21:31,671,000...31,732,118
Ensembl chr21:31,671,000...31,732,118

G

secretory carrier membrane protein 1

decreases expression

Selenium results in decreased expression of SCAMP1 mRNA

NCBI chr 5:78,360,617...78,480,739
Ensembl chr 5:78,360,611...78,480,739

G

secretory carrier membrane protein 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of SCAMP3 mRNA
Selenium results in increased expression of SCAMP3 mRNA

NCBI chr 1:155,255,981...155,262,360
Ensembl chr 1:155,255,979...155,262,430

G

S-phase cyclin A associated protein in the ER

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SCAPER mRNA
Selenium results in decreased expression of SCAPER mRNA

NCBI chr15:76,347,904...76,905,340
Ensembl chr15:76,347,904...76,905,444

G

stearoyl-CoA desaturase

decreases expression

Selenium results in decreased expression of SCD4 mRNA

NCBI chr10:100,347,233...100,364,826
Ensembl chr10:100,347,233...100,364,826

G

Scm polycomb group protein like 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SCML1 mRNA
Selenium results in decreased expression of SCML1 mRNA

NCBI chr X:17,737,128...17,754,985
Ensembl chr X:17,737,449...17,754,988

G

Scm polycomb group protein like 2

decreases expression

Selenium results in decreased expression of SCML2 mRNA

NCBI chr X:18,239,313...18,355,118
Ensembl chr X:18,239,313...18,354,688

G

synthesis of cytochrome C oxidase 2

increases expression

Selenium results in increased expression of SCO2 mRNA

NCBI chr22:50,523,568...50,526,442
Ensembl chr22:50,523,568...50,526,461

G

stimulator of chondrogenesis 1

decreases expression

Selenium results in decreased expression of SCRG1 mRNA

NCBI chr 4:173,384,701...173,519,144
Ensembl chr 4:173,384,701...173,406,380

G

syndecan 3

increases expression

Selenium results in increased expression of SDC3 mRNA

NCBI chr 1:30,869,466...30,909,735
Ensembl chr 1:30,869,466...30,908,758

G

SHH signaling and ciliogenesis regulator SDCCAG8

decreases expression
multiple interactions

Selenium results in decreased expression of SDCCAG8 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of SDCCAG8 mRNA

NCBI chr 1:243,256,041...243,500,091
Ensembl chr 1:243,256,034...243,500,091

G

SEC13 homolog, nuclear pore and COPII coat complex component

increases expression

Selenium results in increased expression of SEC13 mRNA

NCBI chr 3:10,300,931...10,321,112
Ensembl chr 3:10,293,131...10,321,112

G

SEC16 homolog A, endoplasmic reticulum export factor

decreases expression

Selenium results in decreased expression of SEC16A mRNA

NCBI chr 9:136,440,105...136,484,740
Ensembl chr 9:136,440,096...136,483,759

G

SEC22 homolog B, vesicle trafficking protein

decreases expression

Selenium results in decreased expression of SEC22B mRNA

NCBI chr 1:120,150,898...120,176,520
Ensembl chr 1:120,150,898...120,176,520

G

SEC23 homolog B, COPII coat complex component

increases expression

Selenium results in increased expression of SEC23B mRNA

NCBI chr20:18,507,548...18,561,415
Ensembl chr20:18,507,520...18,561,415

G

SEC24 homolog B, COPII coat complex component

decreases expression

Selenium results in decreased expression of SEC24B mRNA

NCBI chr 4:109,433,815...109,540,896
Ensembl chr 4:109,433,772...109,540,896

G

SEC31 homolog A, COPII coat complex component

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SEC31A mRNA

NCBI chr 4:82,818,509...82,900,569
Ensembl chr 4:82,818,509...82,901,166

G

SEC62 homolog, preprotein translocation factor

decreases expression
multiple interactions

Selenium results in decreased expression of SEC62 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of SEC62 mRNA

NCBI chr 3:169,966,807...169,998,373
Ensembl chr 3:169,966,635...169,998,373

G

SECIS binding protein 2 like

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SECISBP2L mRNA
Selenium results in decreased expression of SECISBP2L mRNA

NCBI chr15:48,988,638...49,046,446
Ensembl chr15:48,988,476...49,046,447

G

selenium binding protein 1

increases expression

Selenium results in increased expression of SELENBP1 mRNA; Selenium results in increased expression of SELENBP1 protein

NCBI chr 1:151,364,304...151,372,705
Ensembl chr 1:151,364,304...151,372,707

G

selenoprotein F

decreases expression
decreases response to substance

Selenium deficiency results in decreased expression of SELENOF protein
SELENOF gene polymorphism results in decreased susceptibility to Selenium

PMID:15107826 PMID:16170372

NCBI chr 1:86,862,445...86,914,577
Ensembl chr 1:86,862,445...86,914,424

G

selenoprotein H

affects expression

Selenium affects the expression of SELH mRNA

PMID:19076066 PMID:19106321

NCBI chr11:57,741,491...57,743,550
Ensembl chr11:57,741,491...57,743,554

G

selenoprotein K

affects expression

Selenium affects the expression of SELENOK mRNA

NCBI chr 3:53,884,417...53,891,859
Ensembl chr 3:53,884,417...53,891,885

G

selenoprotein P

multiple interactions
affects abundance
decreases expression
increases transport
affects expression
affects response to substance

[Mercury results in increased expression of SELENOP protein] which results in increased abundance of Selenium; SELENOP gene SNP affects the reaction [SOD2 gene SNP affects the susceptibility to Selenium]; TUBA4A mutant form results in increased abundance of [Selenium binds to SELENOP protein]
SELENOP protein affects the transport of and affects the abundance of Selenium
SELENOP protein affects the abundance of Selenium
Selenium deficiency results in decreased expression of SELENOP mRNA
SELENOP protein results in increased transport of Selenium
Selenium affects the expression of SELENOP protein
SELENOP protein affects the susceptibility to Selenium
SELENOP gene SNP affects the susceptibility to Selenium
Selenium results in decreased expression of SELENOP mRNA

PMID:12521380 PMID:12574155 PMID:15638810 PMID:17014962 PMID:17314095 More...

NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392

G

selenoprotein W

decreases expression
increases expression
increases degradation
affects expression

Selenium deficiency results in decreased expression of SELENOW mRNA
Selenium results in increased expression of SELENOW mRNA
Selenium deficiency results in increased degradation of SELENOW mRNA
Selenium affects the expression of SELENOW mRNA; Selenium deficiency affects the expression of SELENOW protein

PMID:11330475 PMID:12405536 PMID:15670848 PMID:15823556 PMID:16170372 More...

NCBI chr19:47,778,703...47,784,682
Ensembl chr19:47,778,677...47,784,686

G

selectin L

increases expression

Selenium results in increased expression of SELL mRNA

NCBI chr 1:169,690,667...169,711,620
Ensembl chr 1:169,690,665...169,711,702

G

SEM1 26S proteasome subunit

decreases expression

Selenium results in decreased expression of SEM1 mRNA

NCBI chr 7:96,481,626...96,709,846
Ensembl chr 7:96,481,626...96,709,880

G

semaphorin 3B

increases expression

Selenium results in increased expression of SEMA3B mRNA

NCBI chr 3:50,267,652...50,277,546
Ensembl chr 3:50,267,558...50,277,546

G

selenophosphate synthetase 2

affects expression

Selenium affects the expression of SEPHS2 mRNA

NCBI chr16:30,443,631...30,445,874
Ensembl chr16:30,443,631...30,445,874

G

SERPINE1 mRNA binding protein 1

decreases expression

Selenium results in decreased expression of SERBP1 mRNA

NCBI chr 1:67,407,810...67,430,402
Ensembl chr 1:67,407,810...67,430,415

G

serpin family A member 1

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of SERPINA1 mRNA

NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693

G

serpin family A member 3

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in increased expression of SERPINA3N mRNA

NCBI chr14:94,612,391...94,624,053
Ensembl chr14:94,612,384...94,624,055

G

serpin family F member 1

increases expression

Selenium results in increased expression of SERPINF1 mRNA

NCBI chr17:1,762,060...1,777,565
Ensembl chr17:1,762,029...1,777,565

G

SERTA domain containing 2

decreases expression

Selenium results in decreased expression of SERTAD2 mRNA

NCBI chr 2:64,631,621...64,653,913
Ensembl chr 2:64,631,621...64,751,005

G

SET nuclear proto-oncogene

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SET mRNA

NCBI chr 9:128,683,424...128,696,396
Ensembl chr 9:128,683,424...128,696,400

G

SET binding protein 1

decreases expression

Selenium results in decreased expression of SETBP1 mRNA

NCBI chr18:44,680,073...45,068,510
Ensembl chr18:44,680,173...45,068,510

G

SET domain containing 6, protein lysine methyltransferase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SETD6 mRNA
Selenium results in decreased expression of SETD6 mRNA

NCBI chr16:58,515,479...58,523,842
Ensembl chr16:58,515,479...58,523,842

G

SET domain and mariner transposase fusion gene

decreases expression

Selenium results in decreased expression of SETMAR mRNA

NCBI chr 3:4,303,369...4,317,265
Ensembl chr 3:4,303,332...4,317,265

G

splicing factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SF1 mRNA
Selenium results in decreased expression of SF1 mRNA

NCBI chr11:64,764,606...64,778,542
Ensembl chr11:64,764,606...64,778,786

G

splicing factor 3a subunit 2

increases expression
multiple interactions

Selenium results in increased expression of SF3A2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of SF3A2 mRNA

NCBI chr19:2,236,824...2,248,655
Ensembl chr19:2,236,824...2,248,655

G

splicing factor 3b subunit 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SF3B1 mRNA
Selenium results in decreased expression of SF3B1 mRNA

NCBI chr 2:197,389,784...197,435,093
Ensembl chr 2:197,388,515...197,435,079

G

splicing factor 3b subunit 4

increases expression

Selenium results in increased expression of SF3B4 mRNA

NCBI chr 1:149,923,317...149,927,803
Ensembl chr 1:149,923,317...149,927,803

G

SAGA complex associated factor 29

increases expression

Selenium results in increased expression of SGF29 mRNA

NCBI chr16:28,553,920...28,591,790
Ensembl chr16:28,553,915...28,591,790

G

N-sulfoglucosamine sulfohydrolase

increases expression

Selenium results in increased expression of SGSH mRNA

NCBI chr17:80,200,673...80,220,333
Ensembl chr17:80,206,716...80,220,923

G

small G protein signaling modulator 3

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of SGSM3 mRNA

NCBI chr22:40,370,594...40,410,289
Ensembl chr22:40,370,591...40,410,289

G

SH3 and multiple ankyrin repeat domains 2

decreases expression

Selenium results in decreased expression of SHANK2 mRNA

NCBI chr11:70,467,854...71,253,228
Ensembl chr11:70,467,854...71,252,577

G

SH2 domain containing adaptor protein B

increases expression

Selenium results in increased expression of SHB mRNA

NCBI chr 9:37,915,898...38,069,227
Ensembl chr 9:37,915,898...38,069,227

G

serine hydroxymethyltransferase 1

increases expression

Selenium results in increased expression of SHMT1 mRNA

NCBI chr17:18,327,873...18,363,550
Ensembl chr17:18,327,873...18,363,550

G

siah E3 ubiquitin protein ligase 1

decreases expression

Selenium results in decreased expression of SIAH1 mRNA

NCBI chr16:48,360,531...48,387,246
Ensembl chr16:48,356,364...48,448,402

G

single Ig and TIR domain containing

increases expression

Selenium results in increased expression of SIGIRR mRNA

NCBI chr11:405,716...417,397
Ensembl chr11:405,716...417,455

G

SIN3 transcription regulator family member B

increases expression

Selenium results in increased expression of SIN3B mRNA

NCBI chr19:16,829,398...16,880,349
Ensembl chr19:16,829,398...16,880,353

G

signal induced proliferation associated 1 like 3

increases expression

Selenium results in increased expression of SIPA1L3 mRNA

NCBI chr19:37,907,208...38,208,369
Ensembl chr19:37,907,208...38,208,369

G

signal regulatory protein alpha

increases expression

Selenium results in increased expression of SIRPA mRNA

NCBI chr20:1,894,167...1,940,592
Ensembl chr20:1,894,167...1,940,592

G

sirtuin 1

decreases expression

Selenium results in decreased expression of SIRT1 mRNA

NCBI chr10:67,884,656...67,918,390
Ensembl chr10:67,884,656...67,918,390

G

SKI proto-oncogene

increases expression

Selenium results in increased expression of SKI mRNA

NCBI chr 1:2,228,319...2,310,213
Ensembl chr 1:2,227,388...2,310,213

G

SKI3 subunit of superkiller complex

decreases expression

Selenium results in decreased expression of SKIC3 mRNA

NCBI chr 5:95,463,894...95,554,977
Ensembl chr 5:95,461,755...95,555,050

G

solute carrier family 11 member 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SLC11A2 mRNA

NCBI chr12:50,952,263...51,028,886
Ensembl chr12:50,979,401...51,028,566

G

solute carrier family 12 member 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SLC12A2 mRNA

NCBI chr 5:128,083,766...128,189,677
Ensembl chr 5:128,083,766...128,189,677

G

solute carrier family 13 member 4

affects transport
multiple interactions

SLC13A4 protein affects the transport of Selenium
Selenium inhibits the reaction [SLC13A4 protein affects the transport of Sulfates]

NCBI chr 7:135,681,231...135,728,186
Ensembl chr 7:135,681,231...135,729,258

G

solute carrier family 19 member 1

decreases expression

Selenium results in decreased expression of SLC19A1 mRNA

NCBI chr21:45,502,517...45,563,025
Ensembl chr21:45,493,572...45,573,365

G

solute carrier family 19 member 2

decreases expression

Selenium results in decreased expression of SLC19A2 mRNA

NCBI chr 1:169,463,909...169,485,970
Ensembl chr 1:169,463,909...169,485,944

G

solute carrier family 1 member 1

decreases expression

Selenium results in decreased expression of SLC1A1 mRNA

NCBI chr 9:4,490,468...4,587,469
Ensembl chr 9:4,490,468...4,587,469

G

solute carrier family 22 member 18

increases expression

Selenium results in increased expression of SLC22A18 mRNA

NCBI chr11:2,899,691...2,925,246
Ensembl chr11:2,899,721...2,925,246

G

solute carrier family 25 member 1

increases expression

Selenium results in increased expression of SLC25A1 mRNA

NCBI chr22:19,175,581...19,178,736
Ensembl chr22:19,175,581...19,178,739

G

solute carrier family 25 member 12

decreases expression

Selenium results in decreased expression of SLC25A12 mRNA

NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859

G

solute carrier family 25 member 16

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SLC25A16 mRNA
Selenium results in decreased expression of SLC25A16 mRNA

NCBI chr10:68,477,998...68,527,523
Ensembl chr10:68,477,998...68,527,523

G

solute carrier family 25 member 17

decreases expression

Selenium results in decreased expression of SLC25A17 mRNA

NCBI chr22:40,769,630...40,819,346
Ensembl chr22:40,769,630...40,819,399

G

solute carrier family 25 member 22

increases expression

Selenium results in increased expression of SLC25A22 mRNA

NCBI chr11:790,475...798,281
Ensembl chr11:790,475...798,281

G

solute carrier family 25 member 36

decreases expression

Selenium results in decreased expression of SLC25A36 mRNA

NCBI chr 3:140,941,836...140,980,995
Ensembl chr 3:140,941,830...140,980,995

G

solute carrier family 25 member 37

increases expression

Selenium results in increased expression of SLC25A37 mRNA

NCBI chr 8:23,528,956...23,575,463
Ensembl chr 8:23,528,956...23,575,463

G

solute carrier family 25 member 6

increases expression

Selenium results in increased expression of SLC25A6 mRNA

NCBI chr  X:1,386,152...1,392,113
NCBI chr  Y:1,386,152...1,392,113
Ensembl chr  X:1,386,152...1,392,113
Ensembl chr  Y:1,386,152...1,392,113

G

solute carrier family 29 member 1 (Augustine blood group)

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of SLC29A1 mRNA

NCBI chr 6:44,219,615...44,234,142
Ensembl chr 6:44,219,553...44,234,142

G

solute carrier family 35 member D1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SLC35D1 mRNA
Selenium results in decreased expression of SLC35D1 mRNA

NCBI chr 1:66,972,976...67,054,148
Ensembl chr 1:66,999,350...67,054,148

G

solute carrier family 39 member 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of SLC39A1 mRNA

NCBI chr 1:153,959,110...153,968,184
Ensembl chr 1:153,959,099...153,968,184

G

solute carrier family 39 member 7

increases expression

Selenium results in increased expression of SLC39A7 mRNA

NCBI chr 6:33,200,867...33,204,437
Ensembl chr 6:33,200,305...33,204,439

G

solute carrier family 3 member 2

increases expression

Selenium results in increased expression of SLC3A2 mRNA

NCBI chr11:62,856,109...62,888,860
Ensembl chr11:62,856,004...62,888,880

G

solute carrier family 44 member 4

increases expression

Selenium results in increased expression of SLC44A4 mRNA

NCBI chr 6:31,863,192...31,878,997
Ensembl chr 6:31,863,192...31,879,046

G

solute carrier family 4 member 4

decreases expression

Selenium results in decreased expression of SLC4A4 mRNA

NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087

G

solute carrier family 4 member 7

decreases expression

Selenium results in decreased expression of SLC4A7 mRNA

NCBI chr 3:27,372,723...27,484,384
Ensembl chr 3:27,372,723...27,484,420

G

solute carrier family 5 member 5

multiple interactions
increases expression

Selenium inhibits the reaction [Potassium Iodide results in decreased expression of SLC5A5 mRNA]
Selenium results in increased expression of SLC5A5 mRNA

NCBI chr19:17,871,945...17,895,174
Ensembl chr19:17,871,945...17,895,174

G

solute carrier family 6 member 2

decreases expression

Selenium results in decreased expression of SLC6A2 mRNA

NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645

G

solute carrier family 6 member 3

increases activity
increases expression

Selenium deficiency results in increased activity of DAT protein
Selenium deficiency results in increased expression of DAT mRNA

NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440

G

solute carrier family 6 member 8

increases expression

Selenium results in increased expression of SLC6A8 mRNA

NCBI chr X:153,687,926...153,696,593
Ensembl chr X:153,687,926...153,696,588

G

solute carrier family 7 member 11

increases import

SLC7A11 mRNA results in increased import of Selenium

NCBI chr 4:138,164,097...138,312,671
Ensembl chr 4:138,164,097...138,242,349

G

solute carrier family 7 member 5

increases expression

Selenium results in increased expression of SLC7A5 mRNA

NCBI chr16:87,830,023...87,869,507
Ensembl chr16:87,830,023...87,869,507

G

solute carrier family 7 member 8

increases expression

Selenium results in increased expression of SLC7A8 mRNA

NCBI chr14:23,125,295...23,183,660
Ensembl chr14:23,125,295...23,183,674

G

slit guidance ligand 2

decreases expression

Selenium results in decreased expression of SLIT2 mRNA

NCBI chr 4:20,251,905...20,620,561
Ensembl chr 4:20,251,905...20,620,561

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

increases expression

Selenium results in increased expression of SMARCA4 mRNA

NCBI chr19:10,961,030...11,062,273
Ensembl chr19:10,960,932...11,079,426

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5

decreases expression

Selenium results in decreased expression of SMARCA5 mRNA

NCBI chr 4:143,513,702...143,557,486
Ensembl chr 4:143,513,702...143,557,486

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

decreases expression
multiple interactions

Selenium results in decreased expression of SMARCC1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of SMARCC1 mRNA

NCBI chr 3:47,585,269...47,781,893
Ensembl chr 3:47,585,269...47,782,106

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of SMARCD2 mRNA
Selenium results in increased expression of SMARCD2 mRNA

NCBI chr17:63,832,081...63,842,685
Ensembl chr17:63,832,081...63,843,065

G

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3

increases expression

Selenium results in increased expression of SMARCD3 mRNA

NCBI chr 7:151,238,780...151,277,149
Ensembl chr 7:151,238,764...151,277,896

G

structural maintenance of chromosomes flexible hinge domain containing 1

decreases expression

Selenium results in decreased expression of SMCHD1 mRNA

NCBI chr18:2,655,726...2,805,017
Ensembl chr18:2,655,726...2,805,017

G

SMG5 nonsense mediated mRNA decay factor

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SMG5 mRNA
Selenium results in increased expression of SMG5 mRNA

NCBI chr 1:156,249,224...156,291,516
Ensembl chr 1:156,249,224...156,282,825

G

SMG7 nonsense mediated mRNA decay factor

increases expression

Selenium results in increased expression of SMG7 mRNA

NCBI chr 1:183,472,499...183,554,191
Ensembl chr 1:183,472,216...183,598,246

G

spermine oxidase

increases expression

Selenium results in increased expression of SMOX mRNA

NCBI chr20:4,148,828...4,187,727
Ensembl chr20:4,120,980...4,187,747

G

smoothelin

increases expression

Selenium results in increased expression of SMTN mRNA

NCBI chr22:31,064,118...31,104,624
Ensembl chr22:31,064,105...31,104,757

G

SMAD specific E3 ubiquitin protein ligase 1

increases expression

Selenium results in increased expression of SMURF1 mRNA

NCBI chr 7:99,027,440...99,144,108
Ensembl chr 7:99,027,440...99,144,108

G

SMAD specific E3 ubiquitin protein ligase 2

decreases expression

Selenium results in decreased expression of SMURF2 mRNA

NCBI chr17:64,542,282...64,662,307
Ensembl chr17:64,542,282...64,662,307

G

synaptosome associated protein 25

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SNAP25 mRNA
Selenium results in decreased expression of SNAP25 mRNA

NCBI chr20:10,218,830...10,307,418
Ensembl chr20:10,172,395...10,308,258

G

SNF8 subunit of ESCRT-II

increases expression

Selenium results in increased expression of EAP30 mRNA

NCBI chr17:48,929,316...48,944,842
Ensembl chr17:48,929,316...48,944,842

G

small nuclear ribonucleoprotein U4/U6.U5 subunit 27

decreases expression

Selenium results in decreased expression of SNRNP27 mRNA

NCBI chr 2:69,893,956...69,905,236
Ensembl chr 2:69,893,956...69,905,575

G

small nuclear ribonucleoprotein U11/U12 subunit 35

increases expression

Selenium results in increased expression of SNRNP35 mRNA

NCBI chr12:123,458,139...123,473,154
Ensembl chr12:123,458,088...123,473,154

G

small nuclear ribonucleoprotein polypeptides B and B1

increases expression

Selenium results in increased expression of SNRPB mRNA

NCBI chr20:2,461,642...2,470,789
Ensembl chr20:2,461,634...2,470,853

G

small nuclear ribonucleoprotein 13

increases expression

Selenium results in increased expression of SNU13 mRNA

NCBI chr22:41,673,933...41,690,480
Ensembl chr22:41,673,933...41,690,504

G

sorting nexin 1

increases expression

Selenium results in increased expression of SNX1 mRNA

NCBI chr15:64,095,982...64,144,231
Ensembl chr15:64,094,123...64,146,090

G

sorting nexin 17

increases expression

Selenium results in increased expression of SNX17 mRNA

NCBI chr 2:27,370,616...27,377,535
Ensembl chr 2:27,370,496...27,377,535

G

sine oculis binding protein homolog

decreases expression

Selenium results in decreased expression of SOBP mRNA

NCBI chr 6:107,490,117...107,661,306
Ensembl chr 6:107,490,106...107,661,306

G

superoxide dismutase 1

decreases expression

Selenium deficiency results in decreased expression of SOD1 mRNA

NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931

G

superoxide dismutase 2

increases expression
affects response to substance
multiple interactions

Selenium results in increased expression of SOD2 mRNA
SOD2 gene polymorphism affects the susceptibility to Selenium; SOD2 gene SNP affects the susceptibility to Selenium
SELENOP gene SNP affects the reaction [SOD2 gene SNP affects the susceptibility to Selenium]

PMID:17293063 PMID:19074884 PMID:19528373

NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529

G

SON DNA and RNA binding protein

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SON mRNA
Selenium results in decreased expression of SON mRNA

NCBI chr21:33,543,038...33,577,481
Ensembl chr21:33,543,038...33,577,481

G

sorbin and SH3 domain containing 3

increases expression

Selenium results in increased expression of SORBS3 mRNA

NCBI chr 8:22,544,973...22,575,788
Ensembl chr 8:22,544,986...22,575,788

G

sorbitol dehydrogenase

increases expression

Selenium results in increased expression of SORD protein

NCBI chr15:45,023,195...45,077,185
Ensembl chr15:45,023,147...45,077,185

G

SOS Ras/Rac guanine nucleotide exchange factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SOS1 mRNA
Selenium results in decreased expression of SOS1 mRNA

NCBI chr 2:38,981,549...39,124,868
Ensembl chr 2:38,962,206...39,124,345

G

SRY-box transcription factor 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SOX4 mRNA
Selenium results in decreased expression of SOX4 mRNA

NCBI chr 6:21,593,751...21,598,619
Ensembl chr 6:21,593,751...21,598,619

G

SRY-box transcription factor 9

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SOX9 mRNA
Selenium results in decreased expression of SOX9 mRNA

NCBI chr17:72,121,020...72,126,416
Ensembl chr17:72,121,020...72,126,416

G

Sp1 transcription factor

multiple interactions

[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP1 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP1 protein]
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP1 mRNA]; [Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SP1 protein]; [Sodium Selenite results in increased abundance of Selenium] which results in increased expression of SP1 protein

NCBI chr12:53,380,176...53,416,446
Ensembl chr12:53,380,176...53,416,446

G

SP100 nuclear antigen

decreases expression

Selenium results in decreased expression of SP100 mRNA

NCBI chr 2:230,416,201...230,545,606
Ensembl chr 2:230,415,942...230,545,606

G

signal peptidase complex subunit 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SPCS2 mRNA
Selenium results in decreased expression of SPCS2 mRNA

NCBI chr11:74,949,266...74,979,033
Ensembl chr11:74,949,261...74,979,033

G

spen family transcriptional repressor

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SPEN mRNA
Selenium results in decreased expression of SPEN mRNA

NCBI chr 1:15,847,707...15,940,456
Ensembl chr 1:15,836,095...15,940,456

G

SPG7 matrix AAA peptidase subunit, paraplegin

increases expression

Selenium results in increased expression of SPG7 mRNA

NCBI chr16:89,508,388...89,557,768
Ensembl chr16:89,490,719...89,557,766

G

serine peptidase inhibitor, Kunitz type 1

increases expression

Selenium results in increased expression of SPINT1 mRNA

NCBI chr15:40,844,048...40,858,207
Ensembl chr15:40,844,018...40,858,207

G

secreted phosphoprotein 1

decreases expression

Selenium results in decreased expression of SPP1 protein

NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532

G

splA/ryanodine receptor domain and SOCS box containing 3

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of SPSB3 mRNA
Selenium results in increased expression of SPSB3 mRNA

NCBI chr16:1,776,712...1,782,571
Ensembl chr16:1,776,712...1,793,700

G

spectrin alpha, non-erythrocytic 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of SPTAN1 mRNA
Selenium results in increased expression of SPTAN1 mRNA

NCBI chr 9:128,552,587...128,633,662
Ensembl chr 9:128,552,558...128,633,662

G

sequestosome 1

multiple interactions

Selenium inhibits the reaction [arsenite results in increased expression of SQSTM1 protein]

NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078

G

sterol regulatory element binding transcription factor 1

increases expression
multiple interactions

Selenium results in increased expression of SREBF1 mRNA
[Sodium Selenite results in increased abundance of Selenium] inhibits the reaction [[Vancomycin co-treated with Neomycin co-treated with Ampicillin co-treated with Metronidazole co-treated with Amphotericin B] results in increased expression of SREBF1 mRNA]
[[gluconic acid results in increased abundance of Magnesium] co-treated with [Sodium Selenite results in increased abundance of Selenium]] inhibits the reaction [Dietary Fats results in increased expression of SREBF1 mRNA]

PMID:19022953 PMID:28810182 PMID:30031400 PMID:36464106

NCBI chr17:17,811,334...17,836,986
Ensembl chr17:17,810,399...17,837,002

G

sterol regulatory element binding transcription factor 2

increases expression

Selenium results in increased expression of SREBF2 mRNA

NCBI chr22:41,833,105...41,907,305
Ensembl chr22:41,833,105...41,907,306

G

SRSF protein kinase 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SRPK1 mRNA
Selenium results in decreased expression of SRPK1 mRNA

NCBI chr 6:35,832,966...35,921,098
Ensembl chr 6:35,832,966...35,921,342

G

serine/arginine repetitive matrix 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of SRRM2 mRNA

NCBI chr16:2,752,638...2,771,412
Ensembl chr16:2,752,626...2,772,538

G

serine and arginine rich splicing factor 1

increases expression

Selenium results in increased expression of SRSF1 mRNA

NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346

G

serine and arginine rich splicing factor 10

decreases expression

Selenium results in decreased expression of SRSF10 mRNA

NCBI chr 1:23,964,347...23,980,327
Ensembl chr 1:23,964,347...23,980,927

G

serine and arginine rich splicing factor 11

decreases expression

Selenium results in decreased expression of SRSF11 mRNA

NCBI chr 1:70,205,696...70,253,052
Ensembl chr 1:70,205,682...70,253,052

G

serine and arginine rich splicing factor 7

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of SRSF7 mRNA
Selenium results in decreased expression of SRSF7 mRNA

NCBI chr 2:38,743,599...38,751,494
Ensembl chr 2:38,743,599...38,751,494

G

serine and arginine rich splicing factor 9

increases expression

Selenium results in increased expression of SRSF9 mRNA

NCBI chr12:120,461,672...120,469,748
Ensembl chr12:120,461,672...120,495,946

G

SS18 like 2

decreases expression

Selenium results in decreased expression of SS18L2 mRNA

NCBI chr 3:42,581,840...42,596,934
Ensembl chr 3:42,581,840...42,596,934

G

SS nuclear autoantigen 1

increases expression

Selenium results in increased expression of SSNA1 mRNA

NCBI chr 9:137,188,676...137,190,366
Ensembl chr 9:137,188,660...137,190,370

G

structure specific recognition protein 1

increases expression

Selenium results in increased expression of SSRP1 mRNA

NCBI chr11:57,325,988...57,335,892
Ensembl chr11:57,325,986...57,335,892

G

SSX family member 2 interacting protein

decreases expression

Selenium results in decreased expression of SSX2IP mRNA

NCBI chr 1:84,643,706...84,690,745
Ensembl chr 1:84,643,706...84,690,803

G

ST13 Hsp70 interacting protein

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of ST13 mRNA

NCBI chr22:40,824,535...40,856,639
Ensembl chr22:40,824,535...40,856,639

G

ST14 transmembrane serine protease matriptase

increases expression

Selenium results in increased expression of ST14 mRNA

NCBI chr11:130,159,782...130,210,362
Ensembl chr11:130,159,782...130,210,362

G

stabilin 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of STAB1 mRNA
Selenium results in increased expression of STAB1 mRNA

NCBI chr 3:52,495,338...52,524,495
Ensembl chr 3:52,495,338...52,524,495

G

STAG2 cohesin complex component

decreases expression

Selenium results in decreased expression of STAG2 mRNA

NCBI chr X:123,960,560...124,102,656
Ensembl chr X:123,960,212...124,422,664

G

StAR related lipid transfer domain containing 5

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of STARD5 mRNA

NCBI chr15:81,309,053...81,324,141
Ensembl chr15:81,309,053...81,324,183

G

starch binding domain 1

increases expression

Selenium results in increased expression of STBD1 mRNA

NCBI chr 4:76,306,733...76,311,130
Ensembl chr 4:76,306,733...76,311,130

G

serine/threonine kinase 11

increases expression

Selenium results in increased expression of STK11 mRNA

NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431

G

serine/threonine kinase 24

increases expression

Selenium results in increased expression of STK24 mRNA

NCBI chr13:98,445,185...98,577,107
Ensembl chr13:98,445,185...98,577,940

G

serine/threonine kinase 38 like

decreases expression

Selenium results in decreased expression of STK38L mRNA

NCBI chr12:27,244,286...27,325,959
Ensembl chr12:27,243,968...27,325,959

G

stomatin like 2

increases expression

Selenium results in increased expression of STOML2 mRNA

NCBI chr 9:35,099,776...35,103,195
Ensembl chr 9:35,099,776...35,103,195

G

STT3 oligosaccharyltransferase complex catalytic subunit A

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of STT3A mRNA
Selenium results in increased expression of STT3A mRNA

NCBI chr11:125,591,769...125,623,091
Ensembl chr11:125,591,712...125,625,215

G

STIP1 homology and U-box containing protein 1

increases expression

Selenium results in increased expression of STUB1 mRNA

NCBI chr16:680,410...682,801
Ensembl chr16:680,224...682,870

G

serine/threonine/tyrosine interacting like 1

increases expression

Selenium results in increased expression of STYXL1 mRNA

NCBI chr 7:75,996,337...76,048,000
Ensembl chr 7:75,996,338...76,048,004

G

sulfatase 1

decreases expression

Selenium results in decreased expression of SULF1 mRNA

NCBI chr 8:69,466,781...69,660,912
Ensembl chr 8:69,466,624...69,660,915

G

small ubiquitin like modifier 2

increases expression

Selenium results in increased expression of SUMO2 mRNA

NCBI chr17:75,165,586...75,182,959
Ensembl chr17:75,165,586...75,182,959

G

SPT5 homolog, DSIF elongation factor subunit

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of SUPT5H mRNA
Selenium results in increased expression of SUPT5H mRNA

NCBI chr19:39,445,582...39,476,670
Ensembl chr19:39,436,156...39,476,670

G

SPT7 like, STAGA complex subunit gamma

decreases expression

Selenium results in decreased expression of SUPT7L mRNA

NCBI chr 2:27,642,568...27,663,614
Ensembl chr 2:27,650,809...27,663,840

G

SUZ12 polycomb repressive complex 2 subunit

decreases expression

Selenium results in decreased expression of SUZ12 mRNA

NCBI chr17:31,937,007...32,001,038
Ensembl chr17:31,937,007...32,001,038

G

synaptotagmin binding cytoplasmic RNA interacting protein

decreases expression

Selenium results in decreased expression of SYNCRIP mRNA

NCBI chr 6:85,607,784...85,643,870
Ensembl chr 6:85,607,779...85,644,063

G

synaptojanin 2

increases expression

Selenium results in increased expression of SYNJ2 mRNA

NCBI chr 6:157,981,296...158,099,176
Ensembl chr 6:157,981,863...158,099,176

G

synaptopodin

increases expression

Selenium results in increased expression of SYNPO mRNA

NCBI chr 5:150,586,010...150,659,207
Ensembl chr 5:150,601,080...150,659,207

G

transcriptional adaptor 3

increases expression

Selenium results in increased expression of TADA3 mRNA

NCBI chr 3:9,779,967...9,793,011
Ensembl chr 3:9,779,967...9,793,011

G

TATA-box binding protein associated factor 10

increases expression

Selenium results in increased expression of TAF10 mRNA

NCBI chr11:6,606,294...6,612,216
Ensembl chr11:6,606,294...6,612,539

G

TATA-box binding protein associated factor 2

decreases expression

Selenium results in decreased expression of TAF2 mRNA

NCBI chr 8:119,730,774...119,832,841
Ensembl chr 8:119,730,774...119,832,863

G

TATA-box binding protein associated factor 5 like

decreases expression

Selenium results in decreased expression of TAF5L mRNA

NCBI chr 1:229,593,134...229,626,122
Ensembl chr 1:229,593,134...229,626,122

G

transgelin 2

increases expression

Selenium results in increased expression of TAGLN2 mRNA

NCBI chr 1:159,918,111...159,925,507
Ensembl chr 1:159,918,107...159,925,507

G

transaldolase 1

increases expression

Selenium results in increased expression of TALDO1 mRNA

NCBI chr11:747,464...765,012
Ensembl chr11:747,415...765,012

G

transporter 1, ATP binding cassette subfamily B member

increases expression

Selenium results in increased expression of TAP1 mRNA

NCBI chr 6:32,845,209...32,853,704
Ensembl chr 6:32,845,209...32,853,816

G

TAP binding protein

increases expression

Selenium results in increased expression of TAPBP mRNA

NCBI chr 6:33,299,694...33,314,078
Ensembl chr 6:33,299,694...33,314,284

G

TARBP2 subunit of RISC loading complex

increases expression
multiple interactions

Selenium results in increased expression of TARBP2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of TARBP2 mRNA

NCBI chr12:53,500,923...53,506,431
Ensembl chr12:53,500,921...53,506,431

G

taste 2 receptor member 14

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of TAS2R14 mRNA

NCBI chr12:10,937,410...10,939,263
Ensembl chr12:10,937,408...11,171,573

G

transcription activation suppressor

decreases expression

Selenium results in decreased expression of TASOR mRNA

NCBI chr 3:56,620,132...56,683,265
Ensembl chr 3:56,620,132...56,683,265

G

Tax1 binding protein 3

increases expression

Selenium results in increased expression of TAX1BP3 mRNA

NCBI chr17:3,662,895...3,668,578
Ensembl chr17:3,662,895...3,668,679

G

TBC1 domain family member 30

decreases expression

Selenium results in decreased expression of TBC1D30 mRNA

NCBI chr12:64,759,484...64,881,033
Ensembl chr12:64,759,484...64,881,033

G

TBC1 domain family member 8B

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TBC1D8B mRNA
Selenium results in decreased expression of TBC1D8B mRNA

NCBI chr X:106,802,673...106,876,150
Ensembl chr X:106,802,673...106,876,150

G

TBC1 domain family member 9B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TBC1D9B mRNA
Selenium results in increased expression of TBC1D9B mRNA

NCBI chr 5:179,862,071...179,907,897
Ensembl chr 5:179,862,066...179,907,897

G

tubulin folding cofactor B

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TBCB mRNA
Selenium results in increased expression of TBCB mRNA

NCBI chr19:36,114,967...36,125,941
Ensembl chr19:36,114,289...36,125,947

G

transducin beta like 1 X-linked

decreases expression

Selenium results in decreased expression of TBL1X mRNA

NCBI chr X:9,463,295...9,719,740
Ensembl chr X:9,463,320...9,741,037

G

transducin beta like 3

increases expression

Selenium results in increased expression of TBL3 mRNA

NCBI chr16:1,972,053...1,982,929
Ensembl chr16:1,972,053...1,982,929

G

thromboxane A synthase 1

multiple interactions

[Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of TBXAS1 mRNA; [Selenium deficiency co-treated with parthenolide co-treated with Lipopolysaccharides] results in decreased expression of TBXAS1 protein

NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325

G

TRPM8 channel associated factor 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TCAF1 mRNA
Selenium results in decreased expression of TCAF1 mRNA

NCBI chr 7:143,851,375...143,902,176
Ensembl chr 7:143,851,375...143,902,198

G

transcription elongation factor A2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TCEA2 mRNA
Selenium results in increased expression of TCEA2 mRNA

NCBI chr20:64,055,596...64,072,347
Ensembl chr20:64,049,836...64,072,347

G

transcription elongation regulator 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TCERG1 mRNA
Selenium results in decreased expression of TCERG1 mRNA

NCBI chr 5:146,447,330...146,511,961
Ensembl chr 5:146,447,311...146,511,961

G

transcription factor 12

decreases expression

Selenium results in decreased expression of TCF12 mRNA

NCBI chr15:56,918,090...57,291,310
Ensembl chr15:56,918,623...57,299,281

G

transcription factor 7 like 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TCF7L2 mRNA
Selenium results in decreased expression of TCF7L2 mRNA

NCBI chr10:112,950,247...113,167,678
Ensembl chr10:112,950,247...113,167,678

G

t-complex 1

multiple interactions

[Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of TCP1 mRNA

NCBI chr 6:159,778,498...159,789,602
Ensembl chr 6:159,778,498...159,789,703

G

tectonic family member 1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TCTN1 mRNA
Selenium results in decreased expression of TCTN1 mRNA

NCBI chr12:110,614,129...110,649,430
Ensembl chr12:110,614,027...110,663,431

G

TEA domain transcription factor 3

increases expression

Selenium results in increased expression of TEAD3 mRNA

NCBI chr 6:35,473,597...35,497,079
Ensembl chr 6:35,473,597...35,497,079

G

trans-2,3-enoyl-CoA reductase

increases expression

Selenium results in increased expression of TECR mRNA

NCBI chr19:14,527,726...14,565,980
Ensembl chr19:14,517,085...14,565,980

G

telomeric repeat binding factor 1

decreases expression
multiple interactions

Selenium results in decreased expression of TERF1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of TERF1 mRNA

NCBI chr 8:73,008,864...73,048,123
Ensembl chr 8:73,008,856...73,048,123

G

telomerase reverse transcriptase

decreases activity
multiple interactions
decreases expression

Selenium results in decreased activity of TERT protein
[Benzene co-treated with Selenium] results in increased activity of TERT protein
Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TERT mRNA]
Selenium results in decreased expression of TERT mRNA

PMID:16600092 PMID:17948765 PMID:19080380

NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068

G

transcription factor A, mitochondrial

multiple interactions
increases expression

NRF1 protein promotes the reaction [Selenium results in increased expression of TFAM mRNA]

NCBI chr10:58,385,410...58,399,220
Ensembl chr10:58,385,345...58,399,220

G

transcription factor B2, mitochondrial

decreases expression

Selenium results in decreased expression of TFB2M mRNA

NCBI chr 1:246,540,561...246,566,261
Ensembl chr 1:246,540,561...246,566,261

G

transcription factor EB

increases expression

Selenium results in increased expression of TFEB mRNA

NCBI chr 6:41,683,978...41,736,223
Ensembl chr 6:41,683,978...41,736,259

G

transforming growth factor beta 1

multiple interactions
increases expression

Selenium promotes the reaction [Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 mRNA]]; Selenium promotes the reaction [Drugs, Chinese Herbal inhibits the reaction [Carbon Tetrachloride results in increased expression of TGFB1 protein]]
Selenium inhibits the reaction [2-iodohexadecanal results in increased expression of TGFB1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in increased expression of TGFB1 mRNA]
Selenium deficiency results in increased expression of TGFB1 mRNA

PMID:11260395 PMID:14991942 PMID:38013145

NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922

G

transforming growth factor beta receptor 3

decreases expression

Selenium results in decreased expression of TGFBR3 mRNA

NCBI chr 1:91,680,343...91,906,002
Ensembl chr 1:91,680,343...91,906,335

G

trans-golgi network protein 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of TGOLN2 mRNA

NCBI chr 2:85,318,027...85,327,989
Ensembl chr 2:85,318,027...85,328,251

G

tyrosine hydroxylase

increases activity
increases expression
multiple interactions

Selenium deficiency results in increased activity of TH protein
Selenium deficiency results in increased expression of TH mRNA
[Selenium deficiency results in increased activity of TH protein] which results in increased chemical synthesis of Dopamine

NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815

G

THAP domain containing 11

increases expression

Selenium results in increased expression of THAP11 mRNA

NCBI chr16:67,842,320...67,844,195
Ensembl chr16:67,842,320...67,844,195

G

THAP domain containing 7

increases expression

Selenium results in increased expression of THAP7 mRNA

NCBI chr22:20,999,104...21,002,118
Ensembl chr22:20,999,104...21,002,196

G

thrombomodulin

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of THBD mRNA

NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672

G

THO complex subunit 2

decreases expression
multiple interactions

Selenium results in decreased expression of THOC2 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of THOC2 mRNA

NCBI chr X:123,600,569...123,733,052
Ensembl chr X:123,600,561...123,733,056

G

thyroid hormone receptor alpha

multiple interactions

Selenium inhibits the reaction [Iodine results in increased expression of THRA mRNA]

NCBI chr17:40,062,193...40,093,867
Ensembl chr17:40,058,290...40,093,867

G

thyroid hormone receptor beta

multiple interactions

Selenium inhibits the reaction [Iodine results in increased expression of THRB mRNA]

NCBI chr 3:24,117,153...24,495,708
Ensembl chr 3:24,117,153...24,495,756

G

thrombospondin type 1 domain containing 7A

decreases expression

Selenium results in decreased expression of THSD7A mRNA

NCBI chr 7:11,370,365...11,832,198
Ensembl chr 7:11,370,365...11,832,198

G

THUMP domain containing 1

decreases expression

Selenium results in decreased expression of THUMPD1 mRNA

NCBI chr16:20,733,664...20,741,818
Ensembl chr16:20,702,816...20,742,084

G

thymocyte nuclear protein 1

increases expression

Selenium results in increased expression of THYN1 mRNA

NCBI chr11:134,248,282...134,253,352
Ensembl chr11:134,248,279...134,253,370

G

TIA1 cytotoxic granule associated RNA binding protein

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TIA1 mRNA
Selenium results in decreased expression of TIA1 mRNA

NCBI chr 2:70,209,444...70,248,793
Ensembl chr 2:70,209,444...70,248,660

G

translocase of inner mitochondrial membrane 8A

decreases expression

Selenium results in decreased expression of TIMM8A mRNA

NCBI chr X:101,345,661...101,348,742
Ensembl chr X:101,345,661...101,348,742

G

translocase of inner mitochondrial membrane 8 homolog B

decreases expression

Selenium results in decreased expression of TIMM8B mRNA

NCBI chr11:112,084,800...112,086,756
Ensembl chr11:112,084,800...112,086,798

G

translocase of inner mitochondrial membrane 9

decreases expression

Selenium results in decreased expression of TIMM9 mRNA

NCBI chr14:58,408,494...58,427,531
Ensembl chr14:58,408,495...58,427,531

G

TIMP metallopeptidase inhibitor 1

decreases expression
multiple interactions
increases expression

Selenium results in decreased expression of TIMP1 mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP1 protein]
Selenium deficiency results in increased expression of TIMP1 mRNA

PMID:11444866 PMID:17390030 PMID:21144892

NCBI chr X:47,582,436...47,586,789
Ensembl chr X:47,582,408...47,586,789

G

TIMP metallopeptidase inhibitor 2

decreases expression
multiple interactions

Selenium results in decreased expression of TIMP2 mRNA
Selenium inhibits the reaction [T-2 Toxin results in decreased expression of TIMP2 protein]

PMID:17390030 PMID:21144892

NCBI chr17:78,852,977...78,925,387
Ensembl chr17:78,852,977...78,925,387

G

TIMP metallopeptidase inhibitor 3

increases expression
decreases expression

Selenium results in increased expression of TIMP3 mRNA
Selenium results in decreased expression of TIMP3 mRNA

PMID:17390030 PMID:19244175

NCBI chr22:32,801,705...32,863,041
Ensembl chr22:32,801,705...32,863,041

G

TIMP metallopeptidase inhibitor 4

decreases expression

Selenium results in decreased expression of TIMP4 mRNA

NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912

G

tight junction protein 1

multiple interactions

[gamma-Linolenic Acid co-treated with Iodine co-treated with Selenium] results in increased expression of and results in increased localization of TJP1 protein; Selenium results in increased expression of and results in increased localization of TJP1 protein

NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915

G

transketolase

increases expression

Selenium results in increased expression of TKT mRNA

NCBI chr 3:53,224,712...53,256,022
Ensembl chr 3:53,224,712...53,256,052

G

TLE family member 2, transcriptional corepressor

increases expression

Selenium results in increased expression of TLE2 mRNA

NCBI chr19:2,997,644...3,047,635
Ensembl chr19:2,997,639...3,047,635

G

talin 1

increases expression

Selenium results in increased expression of TLN1 mRNA

NCBI chr 9:35,696,948...35,732,195
Ensembl chr 9:35,696,948...35,732,195

G

toll like receptor 10

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in decreased expression of TLR10 mRNA

NCBI chr 4:38,772,238...38,782,990
Ensembl chr 4:38,772,238...38,782,990

G

TM2 domain containing 1

decreases expression

Selenium results in decreased expression of TM2D1 mRNA

NCBI chr 1:61,681,046...61,725,141
Ensembl chr 1:61,681,046...61,725,423

G

transmembrane 9 superfamily member 1

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of TM9SF1 mRNA

NCBI chr14:24,189,149...24,195,441
Ensembl chr14:24,189,149...24,195,687

G

transmembrane 9 superfamily member 4

increases expression

Selenium results in increased expression of TM9SF4 mRNA

NCBI chr20:32,109,714...32,167,256
Ensembl chr20:32,109,714...32,167,258

G

translation machinery associated 7 homolog

decreases expression

Selenium results in decreased expression of TMA7 mRNA

NCBI chr 3:48,440,257...48,444,208
Ensembl chr 3:48,440,257...48,444,208

G

transmembrane channel like 5

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of TMC5 mRNA

NCBI chr16:19,410,539...19,499,113
Ensembl chr16:19,410,496...19,499,113

G

transmembrane protein 168

decreases expression

Selenium results in decreased expression of TMEM168 mRNA

NCBI chr 7:112,762,377...112,790,393
Ensembl chr 7:112,762,377...112,790,423

G

transmembrane protein 222

increases expression

Selenium results in increased expression of TMEM222 mRNA

NCBI chr 1:27,322,163...27,336,400
Ensembl chr 1:27,322,145...27,336,400

G

transmembrane protein 243

decreases expression

Selenium results in decreased expression of TMEM243 mRNA

NCBI chr 7:87,196,160...87,220,587
Ensembl chr 7:87,196,160...87,220,587

G

transmembrane protein 258

decreases expression

Selenium results in decreased expression of TMEM258 mRNA

NCBI chr11:61,788,949...61,792,599
Ensembl chr11:61,768,501...61,792,802

G

transmembrane protein 53

increases expression

Selenium results in increased expression of TMEM53 mRNA

NCBI chr 1:44,653,247...44,674,481
Ensembl chr 1:44,635,238...44,674,481

G

transmembrane protein 63A

increases expression

Selenium results in increased expression of TMEM63A mRNA

NCBI chr 1:225,840,556...225,882,380
Ensembl chr 1:225,845,536...225,882,380

G

TATA element modulatory factor 1

decreases expression

Selenium results in decreased expression of TMF1 mRNA

NCBI chr 3:69,019,827...69,052,333
Ensembl chr 3:69,019,827...69,052,339

G

transmembrane serine protease 2

increases expression

Selenium results in increased expression of TMPRSS2 mRNA

NCBI chr21:41,464,305...41,508,158
Ensembl chr21:41,464,300...41,531,116

G

transmembrane serine protease 6

increases expression

Selenium results in increased expression of TMPRSS6 mRNA

NCBI chr22:37,065,436...37,110,536
Ensembl chr22:37,065,436...37,109,713

G

thymosin beta 15A

decreases expression

Selenium results in decreased expression of TMSB15A mRNA

NCBI chr X:102,513,682...102,516,739
Ensembl chr X:102,513,682...102,516,739

G

thymosin beta 15B

decreases expression

Selenium results in decreased expression of TMSB15B mRNA

NCBI chr  X:103,919,155...103,974,426
Ensembl chr  X:103,918,896...103,966,712
Ensembl chr  X:103,918,896...103,966,712

G

tumor necrosis factor

multiple interactions
increases expression

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of TNF mRNA; Selenium affects the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Selenium inhibits the reaction [Cadmium results in increased expression of and results in increased secretion of TNF protein]; Selenium inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Selenium promotes the reaction [T-2 Toxin results in increased expression of TNF protein]
[Drugs, Chinese Herbal co-treated with Selenium] results in decreased expression of TNF mRNA; [Selenium co-treated with Lipopolysaccharides co-treated with IL4 protein] results in decreased expression of TNF mRNA
[Vanadium co-treated with Selenium co-treated with Vitamin E co-treated with Chromium] inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Selenium affects the reaction [Mercuric Chloride results in decreased expression of TNF protein]
Selenium results in increased expression of TNF mRNA

PMID:10802230 PMID:15862027 PMID:17293063 PMID:18196609 PMID:21481475 More...

NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336

G

TNF alpha induced protein 2

increases expression

Selenium results in increased expression of TNFAIP2 mRNA

NCBI chr14:103,121,469...103,137,439
Ensembl chr14:103,121,476...103,137,439

G

TNF alpha induced protein 6

increases expression

Selenium results in increased expression of TNFAIP6 mRNA

NCBI chr 2:151,357,592...151,381,340
Ensembl chr 2:151,357,592...151,380,046

G

TNF receptor superfamily member 10a

multiple interactions

Selenium analog inhibits the reaction [Diazinon results in decreased expression of TNFRSF10A mRNA]

NCBI chr 8:23,190,452...23,225,102
Ensembl chr 8:23,190,452...23,225,102

G

TNF receptor superfamily member 10b

increases expression

Selenium results in increased expression of TNFRSF10B protein

NCBI chr 8:23,020,133...23,069,031
Ensembl chr 8:23,020,133...23,069,031

G

TNF receptor superfamily member 10c

increases expression

Selenium results in increased expression of TNFRSF10C mRNA

NCBI chr 8:23,102,921...23,117,445
Ensembl chr 8:23,102,921...23,117,445

G

TNF receptor superfamily member 12A

increases expression

Selenium results in increased expression of TNFRSF12A mRNA

NCBI chr16:3,020,368...3,022,383
Ensembl chr16:3,018,445...3,022,383

G

TNF receptor superfamily member 1A

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of TNFRSF1A mRNA; [Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA]; Selenium analog inhibits the reaction [Diazinon results in increased expression of TNFRSF1A mRNA]

PMID:21481475 PMID:27920530

NCBI chr12:6,328,771...6,342,076
Ensembl chr12:6,328,757...6,342,114

G

TNF superfamily member 10

decreases expression

Selenium results in decreased expression of TNFSF10 mRNA

NCBI chr 3:172,505,508...172,523,430
Ensembl chr 3:172,505,508...172,523,475

G

tyrosine kinase non receptor 1

increases expression

Selenium results in increased expression of TNK1 mRNA

NCBI chr17:7,380,047...7,389,742
Ensembl chr17:7,380,534...7,389,774

G

transportin 1

decreases expression

Selenium results in decreased expression of TNPO1 mRNA

NCBI chr 5:72,816,661...72,914,388
Ensembl chr 5:72,816,312...72,916,733

G

transportin 2

decreases expression

Selenium results in decreased expression of TNPO2 mRNA

NCBI chr19:12,699,201...12,723,932
Ensembl chr19:12,699,201...12,724,011

G

tensin 2

increases expression

Selenium results in increased expression of TNS2 mRNA

NCBI chr12:53,046,991...53,064,379
Ensembl chr12:53,046,969...53,064,379

G

transducer of ERBB2, 2

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of TOB2 mRNA

NCBI chr22:41,433,494...41,446,801
Ensembl chr22:41,433,494...41,446,801

G

translocase of outer mitochondrial membrane 7

decreases expression

Selenium results in decreased expression of TOMM7 mRNA

NCBI chr 7:22,812,974...22,822,849
Ensembl chr 7:22,812,628...22,822,849

G

DNA topoisomerase I

decreases expression
multiple interactions

Selenium results in decreased expression of TOP1 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of TOP1 mRNA

NCBI chr20:41,028,822...41,124,487
Ensembl chr20:41,028,822...41,124,487

G

torsin family 1 member A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of TOR1A mRNA

NCBI chr 9:129,812,942...129,824,136
Ensembl chr 9:129,812,942...129,824,244

G

torsin family 3 member A

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of TOR3A mRNA

NCBI chr 1:179,082,070...179,095,996
Ensembl chr 1:179,082,070...179,098,023

G

TOX high mobility group box family member 4

increases expression

Selenium results in increased expression of TOX4 mRNA

NCBI chr14:21,477,195...21,499,170
Ensembl chr14:21,476,597...21,499,175

G

tumor protein p53

multiple interactions
decreases expression
increases expression

[Selenium analog co-treated with Magnesium Oxide analog] inhibits the reaction [Diazinon results in increased expression of TP53 mRNA]; [Selenium co-treated with Vitamin E] results in increased expression of TP53 mRNA
Selenium results in decreased expression of TP53 protein
[Vitamin E co-treated with Selenium] inhibits the reaction [Malathion results in increased expression of TP53 mRNA]; Selenium inhibits the reaction [Cadmium Chloride results in increased expression of TP53 protein]
Selenium results in increased expression of TP53 mRNA

PMID:16600092 PMID:17523932 PMID:19244175 PMID:21628957 PMID:27920530

NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,538

G

triosephosphate isomerase 1

increases expression

Selenium results in increased expression of TPI1 mRNA

NCBI chr12:6,867,420...6,870,948
Ensembl chr12:6,867,119...6,870,948

G

tropomyosin 2

increases expression

Selenium results in increased expression of TPM2 mRNA

NCBI chr 9:35,681,993...35,690,056
Ensembl chr 9:35,681,992...35,690,056

G

tripeptidyl peptidase 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TPP1 mRNA
Selenium results in increased expression of TPP1 mRNA

NCBI chr11:6,612,768...6,619,422
Ensembl chr11:6,612,768...6,619,448

G

translocated promoter region, nuclear basket protein

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TPR mRNA
Selenium results in decreased expression of TPR mRNA

NCBI chr 1:186,311,652...186,375,253
Ensembl chr 1:186,311,652...186,375,693

G

transformer 2 alpha homolog

decreases expression
increases expression

Selenium results in decreased expression of TRA2A mRNA
Selenium results in increased expression of TRA2A mRNA

PMID:17293063 PMID:19244175

NCBI chr 7:23,504,780...23,531,981
Ensembl chr 7:23,504,780...23,532,041

G

TNF receptor associated factor 2

multiple interactions

Selenium analog inhibits the reaction [Diazinon results in increased expression of TRAF2 mRNA]

NCBI chr 9:136,881,958...136,926,607
Ensembl chr 9:136,881,912...136,926,607

G

TNF receptor associated factor 4

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TRAF4 mRNA
Selenium results in increased expression of TRAF4 mRNA

NCBI chr17:28,744,011...28,750,956
Ensembl chr17:28,744,011...28,750,956

G

TRAF-type zinc finger domain containing 1

increases expression

Selenium results in increased expression of TRAFD1 mRNA

NCBI chr12:112,125,560...112,153,604
Ensembl chr12:112,125,538...112,153,604

G

trafficking protein particle complex subunit 14

increases expression

Selenium results in increased expression of TRAPPC14 mRNA

NCBI chr 7:100,154,423...100,158,723
Ensembl chr 7:100,154,420...100,158,723

G

trafficking protein particle complex subunit 2B

decreases expression

Selenium results in decreased expression of TRAPPC2B mRNA

NCBI chr19:57,363,551...57,365,405
Ensembl chr19:57,363,551...57,365,405

G

trafficking protein particle complex subunit 8

decreases expression

Selenium results in decreased expression of TRAPPC8 mRNA

NCBI chr18:31,829,197...31,943,128
Ensembl chr18:31,829,197...31,953,136

G

triggering receptor expressed on myeloid cells 1

multiple interactions

[Cadmium analog co-treated with Selenium analog co-treated with zinc sulfide analog] results in increased expression of TREM1 mRNA

NCBI chr 6:41,267,385...41,286,682
Ensembl chr 6:41,267,926...41,286,682

G

three prime repair exonuclease 1

increases expression

Selenium results in increased expression of TREX1 mRNA

NCBI chr 3:48,465,830...48,467,645
Ensembl chr 3:48,465,811...48,467,645

G

T cell receptor gamma constant 1

decreases expression

Selenium results in decreased expression of TRGC1 mRNA

NCBI chr 7:38,260,088...38,265,678

G

tribbles pseudokinase 2

increases expression

Selenium results in increased expression of TRIB2 mRNA

NCBI chr 2:12,716,936...12,742,734
Ensembl chr 2:12,716,910...12,742,734

G

tribbles pseudokinase 3

decreases expression

Selenium results in decreased expression of TRIB3 mRNA

NCBI chr20:380,760...397,559
Ensembl chr20:362,835...397,559

G

tripartite motif containing 24

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TRIM24 mRNA
Selenium results in decreased expression of TRIM24 mRNA

NCBI chr 7:138,460,259...138,589,996
Ensembl chr 7:138,460,259...138,589,996

G

tripartite motif containing 27

decreases expression

Selenium results in decreased expression of TRIM27 mRNA

NCBI chr 6:28,903,002...28,923,985
Ensembl chr 6:28,903,002...28,923,988

G

tripartite motif containing 28

increases expression

Selenium results in increased expression of TRIM28 mRNA

NCBI chr19:58,544,064...58,550,715
Ensembl chr19:58,544,064...58,550,722

G

tripartite motif containing 29

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TRIM29 mRNA
Selenium results in increased expression of TRIM29 mRNA

NCBI chr11:120,111,286...120,138,113
Ensembl chr11:120,111,286...120,185,529

G

tripartite motif containing 36

decreases expression

Selenium results in decreased expression of TRIM36 mRNA

NCBI chr 5:115,124,772...115,180,294
Ensembl chr 5:115,124,762...115,180,546

G

tripartite motif containing 38

decreases expression

Selenium results in decreased expression of TRIM38 mRNA

NCBI chr 6:25,962,802...25,991,231
Ensembl chr 6:25,962,802...25,991,231

G

tripartite motif containing 52

decreases expression

Selenium results in decreased expression of TRIM52 mRNA

NCBI chr 5:181,249,062...181,261,143
Ensembl chr 5:181,254,077...181,261,150

G

thyroid hormone receptor interactor 6

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TRIP6 mRNA
Selenium results in increased expression of TRIP6 mRNA

NCBI chr 7:100,867,387...100,873,454
Ensembl chr 7:100,867,387...100,873,454

G

tRNA isopentenyltransferase 1

decreases expression

Selenium results in decreased expression of TRIT1 mRNA

NCBI chr 1:39,838,110...39,883,511
Ensembl chr 1:39,838,110...39,883,511

G

tRNA methyltransferase 11 homolog

decreases expression

Selenium results in decreased expression of TRMT11 mRNA

NCBI chr 6:125,986,540...126,272,343
Ensembl chr 6:125,986,479...126,203,817

G

tRNA methyltransferase 61B

decreases expression

Selenium results in decreased expression of TRMT61B mRNA

NCBI chr 2:28,849,821...28,870,309
Ensembl chr 2:28,849,821...28,870,309

G

trophinin

increases expression

Selenium results in increased expression of TRO mRNA

NCBI chr X:54,920,824...54,931,431
Ensembl chr X:54,920,462...54,931,431

G

transient receptor potential cation channel subfamily C member 4

decreases expression

Selenium results in decreased expression of TRPC4 mRNA

NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802

G

transformation/transcription domain associated protein

increases expression

Selenium results in increased expression of TRRAP mRNA

NCBI chr 7:98,878,532...99,013,241
Ensembl chr 7:98,877,933...99,050,831

G

TSC complex subunit 2

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TSC2 mRNA
Selenium results in increased expression of TSC2 mRNA

NCBI chr16:2,047,985...2,089,491
Ensembl chr16:2,047,967...2,089,491

G

tetraspanin 14

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of TSPAN14 mRNA
Selenium results in increased expression of TSPAN14 mRNA

NCBI chr10:80,454,310...80,522,631
Ensembl chr10:80,454,265...80,533,124

G

TSR3 ribosome maturation factor

increases expression

Selenium results in increased expression of TSR3 mRNA

NCBI chr16:1,349,240...1,351,878
Ensembl chr16:1,349,240...1,351,878

G

tumor suppressing subtransferable candidate 4

increases expression

Selenium results in increased expression of TSSC4 mRNA

NCBI chr11:2,400,750...2,403,876
Ensembl chr11:2,400,488...2,403,878

G

tetratricopeptide repeat domain 17

decreases expression

Selenium results in decreased expression of TTC17 mRNA

NCBI chr11:43,358,920...43,494,931
Ensembl chr11:43,358,920...43,494,933

G

tetratricopeptide repeat domain 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TTC3 mRNA
Selenium results in decreased expression of TTC3 mRNA

NCBI chr21:37,073,254...37,203,118
Ensembl chr21:37,073,226...37,203,112

G

tetratricopeptide repeat domain 31

decreases expression
multiple interactions

Selenium results in decreased expression of TTC31 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of TTC31 mRNA

NCBI chr 2:74,483,081...74,494,559
Ensembl chr 2:74,483,073...74,494,559

G

tubulin alpha 1b

increases expression

Selenium results in increased expression of TUBA1B mRNA

NCBI chr12:49,127,782...49,131,395
Ensembl chr12:49,127,782...49,131,397

G

tubulin alpha 1c

increases expression

Selenium results in increased expression of TUBA1C mRNA

NCBI chr12:49,227,926...49,274,600
Ensembl chr12:49,188,736...49,274,600

G

tubulin alpha 4a

increases expression
multiple interactions
increases abundance

Selenium results in increased expression of TUBA4A mRNA
TUBA4A mutant form results in increased abundance of [Selenium binds to SELENOP protein]; TUBA4A mutant form results in increased abundance of [Selenomethionine binds to Selenium]
TUBA4A mutant form results in increased abundance of Selenium

PMID:19244175 PMID:28478440

NCBI chr 2:219,249,710...219,254,740
Ensembl chr 2:219,249,710...219,277,902

G

tubulin beta class I

increases expression

Selenium results in increased expression of TUBB mRNA

NCBI chr 6:30,720,352...30,725,422
Ensembl chr 6:30,717,435...30,725,538

G

tubulin beta 3 class III

increases expression
multiple interactions

Selenium results in increased expression of TUBB3 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of TUBB3 mRNA

NCBI chr16:89,921,925...89,936,097
Ensembl chr16:89,921,392...89,938,761

G

taurine up-regulated 1

decreases expression

Selenium results in decreased expression of TUG1 mRNA

NCBI chr22:30,969,265...30,979,395
Ensembl chr22:30,969,245...30,979,395

G

TUB like protein 3

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TULP3 mRNA
Selenium results in decreased expression of TULP3 mRNA

NCBI chr12:2,890,891...2,941,138
Ensembl chr12:2,877,223...2,941,138

G

terminal uridylyl transferase 7

decreases expression

Selenium results in decreased expression of TUT7 mRNA

NCBI chr 9:86,287,733...86,354,410
Ensembl chr 9:86,287,733...86,354,454

G

taxilin gamma Y-linked (pseudogene)

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of TXLNGY mRNA
Selenium results in decreased expression of TXLNGY mRNA

NCBI chr  Y:19,567,358...19,607,170
Ensembl chr  Y:19,567,382...19,604,120
Ensembl chr  Y:19,567,382...19,604,120

G

thioredoxin

increases expression
affects expression

Selenium results in increased expression of TXN1 mRNA
Selenium affects the expression of TXN1 mRNA

PMID:15792362 PMID:19351701

NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507

G

thioredoxin reductase 1

multiple interactions
decreases expression
affects activity
increases activity
increases expression

[sulforaphane co-treated with Selenium] results in increased activity of TXNRD1 protein; Selenium promotes the reaction [erucin results in increased expression of and results in increased activity of TXNRD1 protein]; Selenium promotes the reaction [iberin results in increased expression of and results in increased activity of TXNRD1 protein]; Selenium promotes the reaction [Selenium results in increased expression of TXNRD1 protein]; Selenium promotes the reaction [sulforaphane results in increased expression of and results in increased activity of TXNRD1 protein]; Selenium results in increased expression of and results in increased activity of TXNRD1 protein
Selenium inhibits the reaction [2-iodohexadecanal results in decreased expression of TXNRD1 mRNA]; Selenium inhibits the reaction [Potassium Iodide results in decreased expression of TXNRD1 mRNA]
Selenium deficiency results in decreased expression of TXNRD1 mRNA
Selenium affects the activity of TXNRD1 protein
Selenium results in increased activity of TXNRD1 protein
Selenium deficiency results in increased expression of TXNRD1 mRNA; Selenium results in increased expression of TXNRD1 mRNA
Selenium deficiency results in decreased expression of TXNRD1 mRNA; Selenium deficiency results in decreased expression of TXNRD1 protein

PMID:12667700 PMID:12949356 PMID:15471857 PMID:15740016 PMID:15792362 More...

NCBI chr12:104,215,779...104,350,307
Ensembl chr12:104,215,779...104,350,307

G

thioredoxin reductase 2

increases activity
decreases expression
increases expression

Selenium results in increased activity of TXNRD2 protein
Selenium deficiency results in decreased expression of TXNRD2 mRNA
Selenium results in increased expression of TXNRD2 mRNA

PMID:15471857 PMID:15792362 PMID:17291446

NCBI chr22:19,875,522...19,941,818
Ensembl chr22:19,875,517...19,941,820

G

thymidine phosphorylase

increases expression

Selenium results in increased expression of TYMP mRNA

NCBI chr22:50,525,752...50,530,085
Ensembl chr22:50,525,752...50,530,032

G

U2 small nuclear RNA auxiliary factor 1

increases expression

Selenium results in increased expression of U2AF1 mRNA

NCBI chr21:43,092,956...43,107,578
Ensembl chr21:43,092,956...43,107,570

G

ubiquitin like modifier activating enzyme 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of UBA1 mRNA
Selenium results in increased expression of UBA1 mRNA

NCBI chr X:47,190,847...47,215,128
Ensembl chr X:47,190,861...47,215,128

G

ubiquitin A-52 residue ribosomal protein fusion product 1

decreases expression

Selenium results in decreased expression of UBA52 mRNA

NCBI chr19:18,563,766...18,577,550
Ensembl chr19:18,571,730...18,577,550

G

ubiquitin like modifier activating enzyme 7

increases expression

Selenium results in increased expression of UBA7 mRNA

NCBI chr 3:49,805,209...49,813,953
Ensembl chr 3:49,805,209...49,813,953

G

ubiquitin associated protein 2

decreases expression

Selenium results in decreased expression of UBAP2 mRNA

NCBI chr 9:33,921,693...34,049,199
Ensembl chr 9:33,921,693...34,049,388

G

ubiquitin associated protein 2 like

increases expression

Selenium results in increased expression of UBAP2L mRNA

NCBI chr 1:154,220,172...154,271,510
Ensembl chr 1:154,220,179...154,271,510

G

ubiquitin conjugating enzyme E2 L3

increases expression

Selenium results in increased expression of UBE2L3 mRNA

NCBI chr22:21,549,447...21,624,034
Ensembl chr22:21,549,447...21,624,034

G

ubiquitin conjugating enzyme E2 V1

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of UBE2V1 mRNA
Selenium results in decreased expression of UBE2V1 mRNA

NCBI chr20:50,081,124...50,115,957
Ensembl chr20:50,081,124...50,115,959

G

ubiquitin conjugating enzyme E2 Z

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of UBE2Z mRNA
Selenium results in increased expression of UBE2Z mRNA

NCBI chr17:48,908,407...48,929,056
Ensembl chr17:48,908,407...48,929,056

G

ubiquitination factor E4B

increases expression

Selenium results in increased expression of UBE4B mRNA

NCBI chr 1:10,032,958...10,181,239
Ensembl chr 1:10,032,832...10,181,239

G

ubiquitin like 3

decreases expression

Selenium results in decreased expression of UBL3 mRNA

NCBI chr13:29,764,371...29,850,617
Ensembl chr13:29,764,371...29,850,617

G

ubinuclein 1

multiple interactions
increases expression
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of UBN1 mRNA; [Selenium co-treated with Vitamin E] results in increased expression of UBN1 mRNA
Selenium results in increased expression of UBN1 mRNA
Selenium results in decreased expression of UBN1 mRNA

NCBI chr16:4,847,481...4,882,401
Ensembl chr16:4,846,665...4,882,401

G

UBX domain protein 1

increases expression

Selenium results in increased expression of UBXN1 mRNA

NCBI chr11:62,676,500...62,679,073
Ensembl chr11:62,676,498...62,679,117

G

UBX domain protein 4

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of UBXD2 mRNA
Selenium results in decreased expression of UBXD2 mRNA

NCBI chr 2:135,741,855...135,785,056
Ensembl chr 2:135,741,734...135,785,056

G

UBX domain protein 6

increases expression

Selenium results in increased expression of UBXN6 mRNA

NCBI chr19:4,445,006...4,457,879
Ensembl chr19:4,444,999...4,457,794

G

ubiquitin recognition factor in ER associated degradation 1

increases expression

Selenium results in increased expression of UFD1 mRNA

NCBI chr22:19,449,911...19,479,193
Ensembl chr22:19,449,911...19,479,202

G

UDP-glucose ceramide glucosyltransferase

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of UGCG mRNA
Selenium results in decreased expression of UGCG mRNA

NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369

G

UDP glucuronosyltransferase family 2 member B17

increases expression

Selenium deficiency results in increased expression of UGT2B1 mRNA

NCBI chr 4:68,537,173...68,576,322
Ensembl chr 4:68,537,173...68,576,413

G

unc-5 netrin receptor B

increases expression

Selenium results in increased expression of UNC5B mRNA

NCBI chr10:71,212,570...71,302,864
Ensembl chr10:71,212,570...71,302,864

G

UPF3A regulator of nonsense mediated mRNA decay

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of UPF3A mRNA
Selenium results in decreased expression of UPF3A mRNA

NCBI chr13:114,281,601...114,305,817
Ensembl chr13:114,281,601...114,305,817

G

UPF3B regulator of nonsense mediated mRNA decay

decreases expression

Selenium results in decreased expression of UPF3B mRNA

NCBI chr X:119,805,311...119,852,963
Ensembl chr X:119,834,022...119,852,998

G

ubiquinol-cytochrome c reductase, complex III subunit X

decreases expression

Selenium results in decreased expression of UQCR10 mRNA

NCBI chr22:29,767,369...29,770,413
Ensembl chr22:29,767,369...29,770,413

G

ubiquinol-cytochrome c reductase binding protein

decreases expression

Selenium results in decreased expression of UQCRB mRNA

NCBI chr 8:96,222,947...96,235,545
Ensembl chr 8:96,222,947...96,235,546

G

ubiquinol-cytochrome c reductase core protein 1

increases expression

Selenium results in increased expression of UQCRC1 mRNA

NCBI chr 3:48,599,002...48,609,646
Ensembl chr 3:48,599,002...48,610,976

G

ubiquinol-cytochrome c reductase hinge protein

decreases expression

Selenium results in decreased expression of UQCRH mRNA

NCBI chr 1:46,303,698...46,316,776
Ensembl chr 1:46,303,698...46,316,776

G

ubiquinol-cytochrome c reductase complex III subunit VII

decreases expression

Selenium results in decreased expression of UQCRQ mRNA

NCBI chr 5:132,866,642...132,868,847
Ensembl chr 5:132,866,630...132,868,847

G

unconventional SNARE in the ER 1

increases expression

Selenium results in increased expression of USE1 mRNA

NCBI chr19:17,215,357...17,219,829
Ensembl chr19:17,215,346...17,219,829

G

upstream transcription factor 2, c-fos interacting

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of USF2 mRNA
Selenium results in increased expression of USF2 mRNA

NCBI chr19:35,268,962...35,279,821
Ensembl chr19:35,268,962...35,279,821

G

ubiquitin specific peptidase 3

decreases expression

Selenium results in decreased expression of USP3 mRNA

NCBI chr15:63,504,593...63,594,633
Ensembl chr15:63,504,511...63,594,640

G

ubiquitin specific peptidase 33

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of USP33 mRNA
Selenium results in decreased expression of USP33 mRNA

NCBI chr 1:77,695,987...77,759,852
Ensembl chr 1:77,695,987...77,759,852

G

ubiquitin specific peptidase 4

decreases expression

Selenium results in decreased expression of USP4 mRNA

NCBI chr 3:49,277,144...49,340,053
Ensembl chr 3:49,277,144...49,340,712

G

ubiquitin specific peptidase 47

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of USP47 mRNA
Selenium results in decreased expression of USP47 mRNA

NCBI chr11:11,841,972...11,961,887
Ensembl chr11:11,841,423...11,961,887

G

ubiquitin specific peptidase 9 X-linked

decreases expression

Selenium results in decreased expression of USP9X mRNA

NCBI chr X:41,085,445...41,236,579
Ensembl chr X:41,085,445...41,236,579

G

ubiquitin specific peptidase like 1

decreases expression

Selenium results in decreased expression of USPL1 mRNA

NCBI chr13:30,617,920...30,660,766
Ensembl chr13:30,617,693...30,660,770

G

UTP11 small subunit processome component

decreases expression

Selenium results in decreased expression of UTP11 mRNA

NCBI chr 1:38,012,734...38,024,820
Ensembl chr 1:38,009,258...38,024,820

G

UTP25 small subunit processome component

decreases expression

Selenium results in decreased expression of UTP25 mRNA

NCBI chr 1:209,827,972...209,857,565
Ensembl chr 1:209,827,972...209,857,565

G

vesicle associated membrane protein 8

increases expression

Selenium results in increased expression of VAMP8 mRNA

NCBI chr 2:85,577,586...85,582,031
Ensembl chr 2:85,561,562...85,582,031

G

valyl-tRNA synthetase 2, mitochondrial

increases expression

Selenium results in increased expression of VARS2 mRNA

NCBI chr 6:30,914,238...30,926,459
Ensembl chr 6:30,914,205...30,926,459

G

vesicle amine transport 1

increases expression

Selenium results in increased expression of VAT1 mRNA

NCBI chr17:43,014,607...43,022,385
Ensembl chr17:43,014,607...43,025,123

G

valosin containing protein lysine methyltransferase

decreases expression

Selenium results in decreased expression of VCPKMT mRNA

NCBI chr14:50,102,716...50,116,572
Ensembl chr14:50,108,632...50,116,600

G

VGF nerve growth factor inducible

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of VGF mRNA

NCBI chr 7:101,162,509...101,169,952
Ensembl chr 7:101,162,509...101,165,569

G

villin like

increases expression

Selenium results in increased expression of VILL mRNA

NCBI chr 3:37,987,978...38,007,185
Ensembl chr 3:37,988,059...38,007,188

G

vimentin

increases expression
multiple interactions

Selenium results in increased expression of VIM mRNA
Selenium deficiency results in increased expression of VIM protein
Selenium inhibits the reaction [Cisplatin results in increased expression of VIM protein]

PMID:16837816 PMID:17109141 PMID:19244175

NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593

G

vasoactive intestinal peptide receptor 1

increases expression

Selenium results in increased expression of VIPR1 mRNA

NCBI chr 3:42,489,299...42,537,568
Ensembl chr 3:42,489,299...42,537,573

G

vitamin K epoxide reductase complex subunit 1

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of VKORC1 mRNA
Selenium results in increased expression of VKORC1 mRNA

NCBI chr16:31,090,854...31,094,797
Ensembl chr16:31,090,842...31,095,980

G

VPS28 subunit of ESCRT-I

increases expression

Selenium results in increased expression of VPS28 mRNA

NCBI chr 8:144,423,617...144,428,548
Ensembl chr 8:144,423,601...144,428,563

G

VPS39 subunit of HOPS complex

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of VPS39 mRNA
Selenium results in increased expression of VPS39 mRNA

NCBI chr15:42,158,701...42,208,304
Ensembl chr15:42,158,701...42,208,307

G

vacuolar protein sorting 4 homolog A

increases expression

Selenium results in increased expression of VPS4A mRNA

NCBI chr16:69,311,350...69,326,939
Ensembl chr16:69,311,350...69,326,939

G

vacuolar protein sorting 72 homolog

increases expression

Selenium results in increased expression of TCFL1 mRNA

NCBI chr 1:151,176,304...151,190,197
Ensembl chr 1:151,176,304...151,195,321

G

WASP family member 2

increases expression
multiple interactions

Selenium results in increased expression of WASF2 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of WASF2 mRNA

NCBI chr 1:27,404,230...27,490,167
Ensembl chr 1:27,404,230...27,490,167

G

WASH complex subunit 2C

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of WASHC2C mRNA

NCBI chr10:45,727,043...45,792,964
Ensembl chr10:45,727,200...45,792,964

G

WASH complex subunit 3

decreases expression

Selenium results in decreased expression of WASHC3 mRNA

NCBI chr12:102,012,840...102,062,124
Ensembl chr12:102,012,840...102,062,149

G

WW domain binding protein 2

increases expression

Selenium results in increased expression of WBP2 mRNA

NCBI chr17:75,845,699...75,856,436
Ensembl chr17:75,845,699...75,856,507

G

WD repeat domain 1

increases expression

Selenium results in increased expression of WDR1 mRNA

NCBI chr 4:10,074,339...10,116,799
Ensembl chr 4:10,068,089...10,116,972

G

WD repeat domain 19

decreases expression
multiple interactions

Selenium results in decreased expression of WDR19 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of WDR19 mRNA

NCBI chr 4:39,182,529...39,285,810
Ensembl chr 4:39,182,504...39,285,810

G

WD repeat domain 45

increases expression

Selenium results in increased expression of WDR45 mRNA

NCBI chr X:49,074,442...49,101,178
Ensembl chr X:49,074,433...49,101,170

G

WD repeat domain 5B

decreases expression

Selenium results in decreased expression of WDR5B mRNA

NCBI chr 3:122,411,846...122,416,062
Ensembl chr 3:122,411,846...122,416,062

G

WD repeat domain 6

increases expression

Selenium results in increased expression of WDR6 mRNA

NCBI chr 3:49,007,391...49,015,951
Ensembl chr 3:49,007,062...49,015,953

G

WAP four-disulfide core domain 2

increases expression

Selenium results in increased expression of WFDC2 mRNA

NCBI chr20:45,469,753...45,481,532
Ensembl chr20:45,469,753...45,481,532

G

Wnt family member 5B

increases expression

Selenium results in increased expression of WNT5B mRNA

NCBI chr12:1,617,056...1,647,212
Ensembl chr12:1,529,891...1,647,212

G

WD repeat containing antisense to TP53

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of WRAP53 mRNA
Selenium results in increased expression of WRAP53 mRNA

NCBI chr17:7,686,071...7,703,502
Ensembl chr17:7,686,071...7,703,502

G

WD repeat and SOCS box containing 1

decreases expression

Selenium results in decreased expression of WSB1 mRNA

NCBI chr17:27,294,114...27,315,926
Ensembl chr17:27,294,076...27,315,926

G

WW domain containing E3 ubiquitin protein ligase 1

decreases expression

Selenium results in decreased expression of WWP1 mRNA

NCBI chr 8:86,342,547...86,468,503
Ensembl chr 8:86,342,547...86,478,420

G

exportin 6

decreases expression
multiple interactions

Selenium results in decreased expression of XPO6 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of XPO6 mRNA

NCBI chr16:28,097,976...28,211,965
Ensembl chr16:28,097,976...28,211,965

G

Y-box binding protein 3

increases expression

Selenium results in increased expression of YBX3 mRNA

NCBI chr12:10,699,089...10,723,323
Ensembl chr12:10,699,089...10,723,323

G

Yip1 domain family member 3

increases expression

Selenium results in increased expression of YIPF3 mRNA

NCBI chr 6:43,511,832...43,516,926
Ensembl chr 6:43,511,832...43,516,985

G

YLP motif containing 1

decreases expression

Selenium results in decreased expression of YLPM1 mRNA

NCBI chr14:74,763,316...74,837,318
Ensembl chr14:74,763,316...74,859,435

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon

decreases expression

Selenium results in decreased expression of YWHAE mRNA

NCBI chr17:1,344,275...1,400,222
Ensembl chr17:1,344,275...1,400,222

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta

multiple interactions

[Selenium co-treated with Vitamin E] results in increased expression of YWHAZ mRNA

NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388

G

zinc finger and BTB domain containing 11

decreases expression

Selenium results in decreased expression of ZBTB11 mRNA

NCBI chr 3:101,648,889...101,677,132
Ensembl chr 3:101,648,889...101,677,135

G

zinc finger and BTB domain containing 44

decreases expression

Selenium results in decreased expression of ZBTB44 mRNA

NCBI chr11:130,226,677...130,314,917
Ensembl chr11:130,226,677...130,314,917

G

zinc finger C2HC-type containing 1A

decreases expression

Selenium results in decreased expression of ZC2HC1A mRNA

NCBI chr 8:78,666,089...78,719,765
Ensembl chr 8:78,666,050...78,719,765

G

zinc finger CCCH-type containing 15

decreases expression
multiple interactions

Selenium results in decreased expression of ZC3H15 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ZC3H15 mRNA

NCBI chr 2:186,486,260...186,509,361
Ensembl chr 2:186,486,253...186,509,361

G

zinc finger CCCH-type containing, antiviral 1

decreases expression

Selenium results in decreased expression of ZC3HAV1 mRNA

NCBI chr 7:139,043,515...139,109,720
Ensembl chr 7:139,043,515...139,132,122

G

zinc finger CCHC-type containing 2

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZCCHC2 mRNA
Selenium results in decreased expression of ZCCHC2 mRNA

NCBI chr18:62,523,025...62,586,729
Ensembl chr18:62,523,025...62,587,709

G

zinc finger CCHC-type containing 24

decreases expression

Selenium results in decreased expression of ZCCHC24 mRNA

NCBI chr10:79,382,325...79,445,624
Ensembl chr10:79,382,325...79,445,624

G

zinc finger CCHC-type containing 8

decreases expression

Selenium results in decreased expression of ZCCHC8 mRNA

NCBI chr12:122,471,600...122,500,932
Ensembl chr12:122,471,600...122,500,932

G

zinc finger CW-type and PWWP domain containing 1

increases expression
multiple interactions

Selenium results in increased expression of ZCWPW1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ZCWPW1 mRNA

NCBI chr 7:100,400,872...100,428,703
Ensembl chr 7:100,400,826...100,428,992

G

zinc finger E-box binding homeobox 1

decreases expression

Selenium results in decreased expression of ZEB1 mRNA

NCBI chr10:31,318,417...31,529,804
Ensembl chr10:31,318,495...31,529,814

G

zyg-11 related cell cycle regulator

increases expression

Selenium results in increased expression of ZER1 mRNA

NCBI chr 9:128,729,786...128,772,486
Ensembl chr 9:128,729,786...128,772,414

G

zinc finger with KRAB and SCAN domains 1

decreases expression

Selenium results in decreased expression of ZKSCAN1 mRNA

NCBI chr 7:100,015,596...100,045,374
Ensembl chr 7:100,015,572...100,041,689

G

zinc finger MYM-type containing 2

decreases expression

Selenium results in decreased expression of ZMYM2 mRNA

NCBI chr13:19,863,840...20,089,115
Ensembl chr13:19,958,677...20,091,829

G

zinc finger MYM-type containing 4

decreases expression

Selenium results in decreased expression of ZMYM4 mRNA

NCBI chr 1:35,268,709...35,422,058
Ensembl chr 1:35,268,709...35,422,058

G

zinc finger protein 12

decreases expression
multiple interactions

Selenium results in decreased expression of ZNF12 mRNA
[Selenium co-treated with Vitamin E] results in decreased expression of ZNF12 mRNA

NCBI chr 7:6,688,433...6,706,947
Ensembl chr 7:6,688,433...6,706,947

G

zinc finger protein 131

decreases expression

Selenium results in decreased expression of ZNF131 mRNA

NCBI chr 5:43,120,914...43,176,324
Ensembl chr 5:43,065,176...43,192,021

G

zinc finger protein 148

decreases expression

Selenium results in decreased expression of ZNF148 mRNA

NCBI chr 3:125,225,669...125,375,354
Ensembl chr 3:125,225,669...125,375,325

G

zinc finger protein 180

decreases expression

Selenium results in decreased expression of ZNF180 mRNA

NCBI chr19:44,474,431...44,500,522
Ensembl chr19:44,474,428...44,500,524

G

zinc finger protein 195

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF195 mRNA
Selenium results in decreased expression of ZNF195 mRNA

NCBI chr11:3,357,927...3,379,146
Ensembl chr11:3,339,261...3,379,222

G

zinc finger protein 211

decreases expression

Selenium results in decreased expression of ZNF211 mRNA

NCBI chr19:57,633,168...57,644,041
Ensembl chr19:57,630,395...57,644,041

G

zinc finger protein 212

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ZNF212 mRNA
Selenium results in increased expression of ZNF212 mRNA

NCBI chr 7:149,239,651...149,255,606
Ensembl chr 7:149,239,651...149,255,606

G

zinc finger protein 219

increases expression
multiple interactions

Selenium results in increased expression of ZNF219 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ZNF219 mRNA

NCBI chr14:21,090,077...21,104,722
Ensembl chr14:21,090,077...21,104,722

G

zinc finger protein 26

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF26 mRNA
Selenium results in decreased expression of ZNF26 mRNA

NCBI chr12:132,986,367...133,027,102
Ensembl chr12:132,986,365...133,032,952

G

zinc finger protein 264

decreases expression

Selenium results in decreased expression of ZNF264 mRNA

NCBI chr19:57,191,500...57,222,846
Ensembl chr19:57,191,500...57,222,846

G

zinc finger protein 274

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF274 mRNA
Selenium results in decreased expression of ZNF274 mRNA

NCBI chr19:58,183,061...58,213,562
Ensembl chr19:58,183,029...58,213,562

G

zinc finger protein 324

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ZNF324 mRNA
Selenium results in increased expression of ZNF324 mRNA

NCBI chr19:58,467,080...58,475,436
Ensembl chr19:58,467,056...58,475,436

G

zinc finger protein 337

decreases expression

Selenium results in decreased expression of ZNF337 mRNA

NCBI chr20:25,673,195...25,696,853
Ensembl chr20:25,673,195...25,696,853

G

zinc finger protein 358

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ZNF358 mRNA
Selenium results in increased expression of ZNF358 mRNA

NCBI chr19:7,513,880...7,521,025
Ensembl chr19:7,515,292...7,521,025

G

zinc finger protein 492

decreases expression

Selenium results in decreased expression of ZNF492 mRNA

NCBI chr19:22,634,324...22,667,671
Ensembl chr19:22,634,324...22,667,671

G

zinc finger protein 500

increases expression

Selenium results in increased expression of ZNF500 mRNA

NCBI chr16:4,744,245...4,767,162
Ensembl chr16:4,748,239...4,767,624

G

zinc finger protein 552

decreases expression

Selenium results in decreased expression of ZNF552 mRNA

NCBI chr19:57,807,082...57,814,913
Ensembl chr19:57,803,841...57,814,913

G

zinc finger protein 573

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF573 mRNA
Selenium results in decreased expression of ZNF573 mRNA

NCBI chr19:37,738,302...37,779,586
Ensembl chr19:37,735,833...37,817,300

G

zinc finger protein 580

multiple interactions
increases expression

[Selenium co-treated with Vitamin E] results in increased expression of ZNF580 mRNA
Selenium results in increased expression of ZNF580 mRNA

NCBI chr19:55,641,002...55,643,470
Ensembl chr19:55,635,016...55,643,470

G

zinc finger protein 586

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF586 mRNA
Selenium results in decreased expression of ZNF586 mRNA

NCBI chr19:57,769,676...57,780,616
Ensembl chr19:57,769,655...57,819,939

G

zinc finger protein 692

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF692 mRNA

NCBI chr 1:248,850,008...248,859,085
Ensembl chr 1:248,850,006...248,859,144

G

zinc finger protein 768

increases expression

Selenium results in increased expression of ZNF768 mRNA

NCBI chr16:30,524,004...30,532,477
Ensembl chr16:30,524,004...30,526,821

G

zinc finger protein 839

multiple interactions

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF839 mRNA

NCBI chr14:102,317,506...102,342,367
Ensembl chr14:102,317,377...102,342,702

G

zinc finger protein 85

multiple interactions
decreases expression

[Selenium co-treated with Vitamin E] results in decreased expression of ZNF85 mRNA
Selenium results in decreased expression of ZNF85 mRNA

NCBI chr19:20,923,251...20,950,697
Ensembl chr19:20,923,222...20,950,697

G

zinc finger protein 91

decreases expression

Selenium results in decreased expression of ZNF91 mRNA

NCBI chr19:23,305,004...23,395,471
Ensembl chr19:23,304,991...23,395,471

G

ZW10 interacting kinetochore protein

decreases expression

Selenium results in decreased expression of ZWINT mRNA

NCBI chr10:56,357,227...56,361,273
Ensembl chr10:56,357,227...56,361,273

G

zyxin

increases expression
multiple interactions

Selenium results in increased expression of ZYX mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ZYX mRNA

NCBI chr 7:143,381,345...143,391,111
Ensembl chr 7:143,381,295...143,391,111

G

zinc finger ZZ-type and EF-hand domain containing 1

increases expression
multiple interactions

Selenium results in increased expression of ZZEF1 mRNA
[Selenium co-treated with Vitamin E] results in increased expression of ZZEF1 mRNA

NCBI chr17:4,004,445...4,143,030
Ensembl chr17:4,004,445...4,143,030

selenium ion

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione peroxidase 2

decreases expression

Selenium decreases expression of Gpx2 mRNA in the jejunum

RGD

NCBI chr14:64,939,158...64,942,745
Ensembl chr14:64,939,152...64,942,746

selenium(2+)

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutathione peroxidase 3

increases expression

selenium increases expression of GPX3 mRNA in colonic epithelium

RGD

NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988

sodium selenide

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

ATP binding cassette subfamily C member 2

multiple interactions

ABCC2 protein affects the reaction [sodium selenide results in increased transport of arsenite]; sodium selenide inhibits the reaction [arsenite results in increased expression of ABCC2 protein]

NCBI chr10:99,782,640...99,852,594
Ensembl chr10:99,782,640...99,852,594

G

ATP binding cassette subfamily C member 4 (PEL blood group)

multiple interactions

sodium selenide inhibits the reaction [arsenite results in increased expression of ABCC4 protein]

NCBI chr13:95,019,835...95,301,451
Ensembl chr13:95,019,835...95,301,475

G

NFE2 like bZIP transcription factor 2

multiple interactions

sodium selenide inhibits the reaction [Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]]; sodium selenide inhibits the reaction [Mercuric Chloride results in increased expression of NFE2L2 protein]

NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756

G

thioredoxin

decreases expression
multiple interactions

sodium selenide results in decreased expression of TXN protein
sodium selenide inhibits the reaction [Mercuric Chloride results in decreased expression of TXN protein]

NCBI chr 9:110,243,810...110,256,507
Ensembl chr 9:110,243,810...110,256,507

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	26034
chemical entity	26024
atom	26009
nonmetal atom	25498
selenium atom	3455
selenium molecular entity	3455
elemental selenium	1646
cyclooctaselenium	0
diselenium	0
selenide +	4
selenide(.1-)	0
selenium ion +	2
Path 2
Term	Annotations
CHEBI ontology	26034
subatomic particle	26009
composite particle	26009
hadron	26020
baryon	26009
nucleon	26009
atomic nucleus	26009
atom	26009
main group element atom	25834
p-block element atom	25834
p-block molecular entity	25829
chalcogen molecular entity	24917
selenium molecular entity	3455
elemental selenium	1646
cyclooctaselenium	0
diselenium	0
selenide +	4
selenide(.1-)	0
selenium ion +	2

paths to the root