Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: LTBP3 (latent transforming growth factor beta binding protein 3) Homo sapiens
Analyze
Symbol: LTBP3
Name: latent transforming growth factor beta binding protein 3
Description: Exhibits transforming growth factor beta binding activity. Involved in positive regulation of mesenchymal stem cell differentiation; positive regulation of mesenchymal stem cell proliferation; and transforming growth factor beta activation. Localizes to collagen-containing extracellular matrix. Implicated in brachyolmia-amelogenesis imperfecta syndrome and geleophysic dysplasia 3.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DASS; DKFZp586M2123; FLJ33431; FLJ39893; FLJ42533; FLJ44138; FLJ45576; GPHYSD3; latent TGF beta binding protein 3; latent-transforming growth factor beta-binding protein 3; LTBP-3; LTBP2; pp6425; STHAG6
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: This gene (GeneID: 4054) was identified as LTBP2 in PMID: 7719025. The official symbol for this gene is now LTBP3. [27 Jan 2017]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1165,538,805 - 65,558,930 (-)EnsemblGRCh38hg38GRCh38
GRCh381165,538,559 - 65,558,389 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371165,306,030 - 65,325,858 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,062,850 - 65,082,006 (-)NCBINCBI36hg18NCBI36
Build 341165,062,851 - 65,082,006NCBI
Celera1162,632,308 - 62,652,081 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,633,038 - 61,652,692 (-)NCBIHuRef
CHM1_11165,189,927 - 65,209,594 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on LTBP3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736405
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.