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Gene: APEH (acylaminoacyl-peptide hydrolase) Homo sapiens
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Symbol: APEH
Name: acylaminoacyl-peptide hydrolase
Description: Exhibits identical protein binding activity; omega peptidase activity; and serine-type endopeptidase activity. Involved in amyloid-beta metabolic process and proteolysis. Localizes to cytosol and nuclear membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AARE; ACPH; acyl-peptide hydrolase; acylamino-acid-releasing enzyme; acylaminoacyl-peptidase; APH; D3F15S2; D3S48E; DNF15S2; MGC2178; N-acylaminoacyl-peptide hydrolase; OPH; oxidized protein hydrolase
Orthologs:
Mus musculus (house mouse) : Apeh (acylpeptide hydrolase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Apeh (acylaminoacyl-peptide hydrolase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Apeh (acylaminoacyl-peptide hydrolase)
Pan paniscus (bonobo/pygmy chimpanzee) : APEH (acylaminoacyl-peptide hydrolase)
Canis lupus familiaris (dog) : APEH (acylaminoacyl-peptide hydrolase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Apeh (acylaminoacyl-peptide hydrolase)
Sus scrofa (pig) : APEH (acylaminoacyl-peptide hydrolase)
Chlorocebus sabaeus (African green monkey) : APEH (acylaminoacyl-peptide hydrolase)
Heterocephalus glaber (naked mole-rat) : Apeh (acylaminoacyl-peptide hydrolase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl349,674,014 - 49,683,971 (+)EnsemblGRCh38hg38GRCh38
GRCh38349,673,102 - 49,683,971 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37349,711,427 - 49,720,936 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36349,686,439 - 49,695,938 (+)NCBINCBI36hg18NCBI36
Build 34349,686,438 - 49,695,937NCBI
Celera349,676,127 - 49,685,626 (+)NCBI
Cytogenetic Map3p21.31NCBI
HuRef349,770,415 - 49,779,914 (+)NCBIHuRef
CHM1_1349,663,491 - 49,672,990 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on APEH
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735668
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.