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Gene: TAF2 (TATA-box binding protein associated factor 2) Homo sapiens
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Symbol: TAF2
Name: TATA-box binding protein associated factor 2
Description: Exhibits TFIID-class transcription factor complex binding activity and transcription regulatory region DNA binding activity. Involved in G2/M transition of mitotic cell cycle; positive regulation of transcription by RNA polymerase II; and transcription initiation from RNA polymerase II promoter. Localizes to the transcription factor TFIID complex and transcription factor TFTC complex. Implicated in autosomal recessive non-syndromic intellectual disability.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 150 kDa cofactor of initiator function; CIF150; cofactor of initiator function, 150kD subunit; MRT40; RNA polymerase II TBP-associated factor subunit B; TAF(II)150; TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa; TAF2B; TAFII-150; TAFII150; TATA box binding protein (TBP)-associated factor, RNA polymerase II, B, 150kD; TATA box binding protein associated factor 2; TBP-associated factor 150 kDa; transcription initiation factor TFIID 150 kDa subunit; transcription initiation factor TFIID subunit 2
Orthologs:
Mus musculus (house mouse) : Taf2 (TATA-box binding protein associated factor 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Taf2 (TATA-box binding protein associated factor 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Taf2 (TATA-box binding protein associated factor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TAF2 (TATA-box binding protein associated factor 2)
Canis lupus familiaris (dog) : TAF2 (TATA-box binding protein associated factor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Taf2 (TATA-box binding protein associated factor 2)
Sus scrofa (pig) : TAF2 (TATA-box binding protein associated factor 2)
Chlorocebus sabaeus (African green monkey) : TAF2 (TATA-box binding protein associated factor 2)
Heterocephalus glaber (naked mole-rat) : Taf2 (TATA-box binding protein associated factor 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl8119,730,774 - 119,832,841 (-)Ensembl
GRCh388119,730,773 - 119,832,858 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh378120,743,014 - 120,845,074 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 368120,812,195 - 120,914,255 (-)NCBINCBI36hg18NCBI36
Build 348120,812,195 - 120,914,255NCBI
Celera8116,932,070 - 117,034,135 (-)NCBI
Cytogenetic Map8q24.12NCBI
HuRef8116,063,646 - 116,165,955 (-)NCBIHuRef
CHM1_18120,783,731 - 120,885,905 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - uncurated

Genomics

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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TAF2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353856
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.