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Gene: NFS1 (NFS1 cysteine desulfurase) Homo sapiens
Symbol: NFS1
Name: NFS1 cysteine desulfurase
Description: Exhibits cysteine desulfurase activity and protein homodimerization activity. Involved in iron incorporation into metallo-sulfur cluster. Localizes to the cytosol; mitochondrial matrix; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: cysteine desulfurase, mitochondrial; HUSSY-08; IscS; NFS1 nitrogen fixation 1 homolog; NFS1, cysteine desulfurase; NIFS; nitrogen fixation 1 (S. cerevisiae, homolog); nitrogen-fixing bacteria S-like protein
Mus musculus (house mouse) : Nfs1 (nitrogen fixation gene 1 (S. cerevisiae))  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfs1 (NFS1 cysteine desulfurase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfs1 (NFS1 cysteine desulfurase)
Pan paniscus (bonobo/pygmy chimpanzee) : NFS1 (NFS1 cysteine desulfurase)
Canis lupus familiaris (dog) : NFS1 (NFS1 cysteine desulfurase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfs1 (NFS1 cysteine desulfurase)
Sus scrofa (pig) : NFS1 (NFS1 cysteine desulfurase)
Chlorocebus sabaeus (green monkey) : NFS1 (NFS1 cysteine desulfurase)
Heterocephalus glaber (naked mole-rat) : Nfs1 (NFS1 cysteine desulfurase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2035,668,052 - 35,699,355 (-)Ensembl
GRCh382035,668,052 - 35,699,352 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372034,256,610 - 34,287,287 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362033,720,025 - 33,750,688 (-)NCBINCBI36hg18NCBI36
Build 342033,745,916 - 33,750,688NCBI
Celera2031,004,905 - 31,035,569 (-)NCBI
Cytogenetic Map20q11.22NCBI
HuRef2031,034,024 - 31,064,670 (-)NCBIHuRef
CHM1_12034,158,261 - 34,189,218 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NFS1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350532
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.