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Gene: POLR2M (RNA polymerase II subunit M) Homo sapiens
Symbol: POLR2M
Name: RNA polymerase II subunit M
Description: Predicted to have DNA-directed 5'-3' RNA polymerase activity. Predicted to be involved in intracellular signal transduction. Localizes to the RNA polymerase II, holoenzyme and nuclear envelope.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp586F1918; DNA-directed RNA polymerase II subunit M; DNA-directed RNA polymerase II subunit M, isoforms 4/5; GCOM1; Gdown; Gdown1; glutamate receptor, ionotropic; glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A; Glutamate receptor-like protein 1A; GRINL1A; GRINL1A downstream protein Gdown4; polymerase (RNA) II (DNA directed) polypeptide M; polymerase (RNA) II subunit M; protein GRINL1A, isoforms 4/5
Mus musculus (house mouse) : Polr2m (polymerase (RNA) II (DNA directed) polypeptide M)  MGI  Alliance
Rattus norvegicus (Norway rat) : Polr2m (RNA polymerase II subunit M)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Polr2m (RNA polymerase II subunit M)
Pan paniscus (bonobo/pygmy chimpanzee) : POLR2M (RNA polymerase II subunit M)
Canis lupus familiaris (dog) : POLR2M (RNA polymerase II subunit M)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Polr2m (RNA polymerase II subunit M)
Sus scrofa (pig) : POLR2M (RNA polymerase II subunit M)
Chlorocebus sabaeus (green monkey) : POLR2M (RNA polymerase II subunit M)
Heterocephalus glaber (naked mole-rat) : Polr2m (RNA polymerase II subunit M)
more info ...
Related Pseudogenes: GCOM2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1557,706,695 - 57,782,762 (+)Ensembl
GRCh381557,706,521 - 57,717,557 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371557,998,901 - 58,009,753 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361555,786,193 - 55,797,045 (+)NCBINCBI36hg18NCBI36
Build 341555,786,206 - 55,797,044NCBI
Celera1534,888,598 - 34,899,440 (+)NCBI
Cytogenetic Map15q21.3NCBI
HuRef1534,821,915 - 34,832,716 (+)NCBIHuRef
CHM1_11558,116,175 - 58,127,727 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POLR2M
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731440
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.