PARP1 Human (+)-catechin multiple interactions ISO Parp1 (Mus musculus) 6480464 Catechin inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein] CTD PMID:16753784 PARP1 Human (+)-catechin increases expression ISO Parp1 (Mus musculus) 6480464 Catechin results in increased expression of PARP1 protein CTD PMID:16753784 PARP1 Human (+)-dexrazoxane multiple interactions ISO Parp1 (Mus musculus) 6480464 Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 mRNA] and Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 protein] CTD PMID:28973540 PARP1 Human (+)-pilocarpine affects expression ISO Parp1 (Rattus norvegicus) 6480464 Pilocarpine affects the expression of PARP1 protein CTD PMID:25101675 PARP1 Human (+)-pilocarpine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein] more ... CTD PMID:31396050 PARP1 Human (+)-sesamin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 sesamin inhibits the reaction [Glucose results in increased cleavage of PARP1 protein] CTD PMID:22524206 PARP1 Human (+)-Tetrandrine increases cleavage EXP 6480464 tetrandrine results in increased cleavage of PARP1 protein CTD PMID:26822499 PARP1 Human (-)-anisomycin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Colistin co-treated with Anisomycin] results in increased cleavage of PARP1 protein and Anisomycin inhibits the reaction [gamma-glutamylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of PARP1 protein]] CTD PMID:28842171 and PMID:34767868 PARP1 Human (-)-bornyl-caffeate increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 bornyl caffeate results in increased cleavage of PARP1 protein CTD PMID:24907532 PARP1 Human (-)-epigallocatechin 3-gallate increases activity EXP 6480464 epigallocatechin gallate results in increased activity of PARP1 protein CTD PMID:15657356 PARP1 Human (-)-epigallocatechin 3-gallate affects cleavage EXP 6480464 epigallocatechin gallate affects the cleavage of PARP1 protein CTD PMID:23954321 PARP1 Human (-)-epigallocatechin 3-gallate affects activity ISO Parp1 (Mus musculus) 6480464 epigallocatechin gallate affects the activity of PARP1 protein CTD PMID:25955525 PARP1 Human (-)-epigallocatechin 3-gallate multiple interactions EXP 6480464 epigallocatechin gallate inhibits the reaction [potassium chromate(VI) results in increased cleavage of and results in increased activity of PARP1 protein] CTD PMID:22079256 PARP1 Human (-)-epigallocatechin 3-gallate increases cleavage EXP 6480464 epigallocatechin gallate results in increased cleavage of PARP1 protein CTD PMID:15705601 and PMID:15764647 PARP1 Human (-)-gambogic acid multiple interactions EXP 6480464 [gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein more ... CTD PMID:19084572 more ... PARP1 Human (-)-gambogic acid decreases expression EXP 6480464 gambogic acid results in decreased expression of PARP1 mRNA CTD PMID:19084572 PARP1 Human (-)-gambogic acid increases cleavage EXP 6480464 gambogic acid results in increased cleavage of PARP1 protein CTD PMID:19084572 more ... PARP1 Human (-)-noscapine increases cleavage EXP 6480464 Noscapine results in increased cleavage of PARP1 protein CTD PMID:22848370 PARP1 Human (-)-selegiline multiple interactions ISO Parp1 (Mus musculus) 6480464 Selegiline inhibits the reaction [linsidomine results in decreased expression of PARP1 protein] CTD PMID:12880480 PARP1 Human (20R)-protopanaxadiol increases expression EXP 6480464 protopanaxadiol results in increased expression of PARP1 mRNA CTD PMID:31805304 PARP1 Human (20S)-ginsenoside Rg3 multiple interactions EXP 6480464 [ginsenoside Rg3 co-treated with osimertinib] results in increased cleavage of PARP1 protein more ... CTD PMID:24793912 more ... PARP1 Human (20S)-ginsenoside Rg3 increases cleavage EXP 6480464 ginsenoside Rg3 results in increased cleavage of PARP1 protein CTD PMID:22101440 PARP1 Human (3,4-dihydroxyphenyl)acetic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:10318960 PARP1 Human (aminomethyl)phosphonic acid increases cleavage EXP 6480464 1-aminomethylphosphonic acid results in increased cleavage of PARP1 protein CTD PMID:23983455 PARP1 Human (aminomethyl)phosphonic acid multiple interactions EXP 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of PARP1 protein CTD PMID:26006246 PARP1 Human (aminooxy)acetic acid multiple interactions EXP 6480464 [Aminooxyacetic Acid results in decreased metabolism of selenomethylselenocysteine] which results in decreased expression of PARP1 protein modified form CTD PMID:25321483 PARP1 Human (R)-adrenaline decreases cleavage ISO Parp1 (Mus musculus) 6480464 Epinephrine results in decreased cleavage of PARP1 protein CTD PMID:36423730 PARP1 Human (R)-adrenaline decreases cleavage EXP 6480464 Epinephrine results in decreased cleavage of PARP1 protein CTD PMID:36423730 PARP1 Human (R,R,R)-alpha-tocopherol multiple interactions EXP 6480464 alpha-Tocopherol inhibits the reaction [Tamoxifen results in increased cleavage of PARP1 protein] CTD PMID:14645110 PARP1 Human (R,R,R)-alpha-tocopherol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 alpha-Tocopherol inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein] CTD PMID:24448832 PARP1 Human (S)-colchicine increases cleavage EXP 6480464 Colchicine results in increased cleavage of PARP1 protein CTD PMID:33684465 PARP1 Human (S)-naringenin increases cleavage EXP 6480464 naringenin results in increased cleavage of PARP1 protein CTD PMID:27838343 PARP1 Human (S)-naringenin multiple interactions EXP 6480464 naringenin inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein] CTD PMID:31254498 PARP1 Human (S)-nicotine multiple interactions EXP 6480464 Nicotine inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form] more ... CTD PMID:20457658 more ... PARP1 Human (S)-nicotine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Folic Acid inhibits the reaction [Nicotine results in decreased expression of PARP1 protein] CTD PMID:29972271 PARP1 Human (S)-nicotine decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Nicotine results in decreased expression of PARP1 protein CTD PMID:29972271 PARP1 Human (S)-ropivacaine increases cleavage EXP 6480464 Ropivacaine results in increased cleavage of PARP1 protein CTD PMID:15538973 PARP1 Human (S)-ropivacaine increases expression EXP 6480464 Ropivacaine results in increased expression of PARP1 protein CTD PMID:28079261 PARP1 Human (S)-ropivacaine multiple interactions EXP 6480464 BCL2 protein inhibits the reaction [Ropivacaine results in increased cleavage of PARP1 protein] and CLU protein inhibits the reaction [Ropivacaine results in increased cleavage of PARP1 protein] CTD PMID:15538973 PARP1 Human 1'-acetoxychavicol acetate multiple interactions EXP 6480464 1'-acetoxychavicol acetate promotes the reaction [TNF protein results in increased cleavage of PARP1 protein] CTD PMID:15905586 PARP1 Human 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Parp1 (Rattus norvegicus) 6480464 o and p'-DDT affects the expression of PARP1 mRNA CTD PMID:17984292 PARP1 Human 1,2-dimethylhydrazine decreases expression ISO Parp1 (Rattus norvegicus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of PARP1 mRNA CTD PMID:32387197 PARP1 Human 1,2-dimethylhydrazine multiple interactions ISO Parp1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PARP1 mRNA] CTD PMID:22206623 PARP1 Human 1,2-dimethylhydrazine increases expression ISO Parp1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of PARP1 mRNA CTD PMID:22206623 PARP1 Human 1,3-dichloropropan-2-ol multiple interactions ISO Parp1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [1 and 3-dichloro-2-propanol results in increased cleavage of PARP1 protein] CTD PMID:29248572 PARP1 Human 1,3-dichloropropan-2-ol increases cleavage ISO Parp1 (Mus musculus) 6480464 1 and 3-dichloro-2-propanol results in increased cleavage of PARP1 protein CTD PMID:29248572 PARP1 Human 1,3-dinitrobenzene increases cleavage ISO Parp1 (Mus musculus) 6480464 3-dinitrobenzene results in increased cleavage of PARP1 protein CTD PMID:19477251 PARP1 Human 1,3-dinitrobenzene multiple interactions ISO Parp1 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [3-dinitrobenzene results in increased cleavage of PARP1 protein] CTD PMID:19477251 PARP1 Human 1,4-dithiothreitol multiple interactions ISO Parp1 (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:11035063 PARP1 Human 1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein] and Dithiothreitol inhibits the reaction [withaferin A results in increased cleavage of PARP1 protein] CTD PMID:18022205 and PMID:20438634 PARP1 Human 1,4-naphthoquinone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:30871965 PARP1 Human 1,4-naphthoquinone increases cleavage EXP 6480464 1 and 4-naphthoquinone analog results in increased cleavage of PARP1 protein CTD PMID:30871965 PARP1 Human 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile increases cleavage EXP 6480464 Citalopram results in increased cleavage of PARP1 protein CTD PMID:10487422 PARP1 Human 1-chloro-2,4-dinitrobenzene affects binding EXP 6480464 Dinitrochlorobenzene binds to PARP1 protein CTD PMID:32991956 PARP1 Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO Parp1 (Mus musculus) 6480464 [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:10318960 PARP1 Human 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:10318960 PARP1 Human 1-monopalmitoylglycerol multiple interactions EXP 6480464 palmitoyl glycerol results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:37466199 PARP1 Human 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [delta(12)-prostaglandin J(2) co-treated with 9-deoxy-delta-9-prostaglandin D2 co-treated with 15-deoxy-delta(12 and 14)-prostaglandin J2] results in increased cleavage of PARP1 protein CTD PMID:23973622 PARP1 Human 15-deoxy-Delta(12,14)-prostaglandin J2 increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased cleavage of PARP1 protein CTD PMID:23973622 PARP1 Human 15-deoxy-Delta(12,14)-prostaglandin J2 increases cleavage EXP 6480464 15-deoxy-delta(12 and 14)-prostaglandin J2 results in increased cleavage of PARP1 protein CTD PMID:15498850 PARP1 Human 17alpha-ethynylestradiol multiple interactions ISO Parp1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PARP1 mRNA CTD PMID:17942748 PARP1 Human 17beta-estradiol decreases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Estradiol results in decreased cleavage of PARP1 protein CTD PMID:24894866 PARP1 Human 17beta-estradiol decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of PARP1 mRNA CTD PMID:32145629 PARP1 Human 17beta-estradiol increases cleavage EXP 6480464 Estradiol results in increased cleavage of PARP1 protein CTD PMID:21732360 PARP1 Human 17beta-estradiol multiple interactions EXP 6480464 [ESR2 protein results in increased susceptibility to Estradiol] which results in increased cleavage of PARP1 protein more ... CTD PMID:21732360 more ... PARP1 Human 17beta-estradiol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [Estradiol results in decreased cleavage of PARP1 protein] CTD PMID:24894866 PARP1 Human 17beta-estradiol 3-benzoate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [estradiol 3-benzoate results in increased cleavage of PARP1 protein] CTD PMID:24316378 PARP1 Human 17beta-estradiol 3-benzoate increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in increased cleavage of PARP1 protein CTD PMID:24316378 PARP1 Human 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone increases cleavage EXP 6480464 2' more ... CTD PMID:38521250 PARP1 Human 2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2' more ... CTD PMID:38521250 PARP1 Human 2'-Hydroxy-2,3,5'-trimethoxychalcone increases cleavage EXP 6480464 2-hydroxy-3' more ... CTD PMID:30408460 PARP1 Human 2'-Hydroxy-2,3,5'-trimethoxychalcone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [2-hydroxy-3' more ... CTD PMID:30408460 PARP1 Human 2,2',4,4',5,5'-hexachlorobiphenyl increases activity EXP 6480464 2 more ... CTD PMID:16884709 PARP1 Human 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Parp1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:30029115 and PMID:31826744 PARP1 Human 2,2',5,5'-tetrachlorobiphenyl multiple interactions EXP 6480464 [2 more ... CTD PMID:19433264 PARP1 Human 2,2',5,5'-tetrachlorobiphenyl increases activity EXP 6480464 2 more ... CTD PMID:19433264 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [3-aminobenzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD] more ... CTD PMID:17669606 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Parp1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of PARP1 mRNA CTD PMID:34747641 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein] CTD PMID:25843524 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PARP1 mRNA CTD PMID:22574217 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Parp1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of PARP1 mRNA CTD PMID:21570461 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Parp1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of PARP1 mRNA and Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to PARP1 promoter] CTD PMID:17942748 and PMID:19654925 PARP1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Parp1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PARP1 mRNA CTD PMID:19465110 PARP1 Human 2,4-D multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [2 more ... CTD PMID:36085217 PARP1 Human 2,6-di-tert-butyl-4-methylphenol multiple interactions EXP 6480464 Butylated Hydroxytoluene inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein] and Butylated Hydroxytoluene inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of PARP1 protein] CTD PMID:2126186 PARP1 Human 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions ISO Parp1 (Mus musculus) 6480464 Verapamil inhibits the reaction [PARP1 gene mutant form results in decreased uptake of Doxorubicin] CTD PMID:15861398 PARP1 Human 2-(3,4-dimethoxyphenyl)-5-\{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino\}-2-(propan-2-yl)pentanenitrile multiple interactions EXP 6480464 [Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein more ... CTD PMID:24373880 PARP1 Human 2-amino-14,16-dimethyloctadecan-3-ol decreases expression EXP 6480464 2-amino-14 and 16-dimethyloctadecan-3-ol results in decreased expression of PARP1 protein CTD PMID:32044396 PARP1 Human 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Parp1 (Mus musculus) 6480464 [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein and gentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein] CTD PMID:20558151 PARP1 Human 2-amino-2-deoxy-D-glucopyranose increases cleavage EXP 6480464 Glucosamine results in increased cleavage of PARP1 protein CTD PMID:16850161 PARP1 Human 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] CTD PMID:16850161 PARP1 Human 2-arachidonoylglycerol multiple interactions EXP 6480464 GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:32357311 PARP1 Human 2-arachidonoylglycerol increases cleavage EXP 6480464 glyceryl 2-arachidonate results in increased cleavage of PARP1 protein CTD PMID:29441458 and PMID:32357311 PARP1 Human 2-bromohexadecanoic acid multiple interactions EXP 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PARP1 protein] CTD PMID:38195004 PARP1 Human 2-deoxy-D-glucose multiple interactions EXP 6480464 Deoxyglucose inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] more ... CTD PMID:25246272 and PMID:34053323 PARP1 Human 2-deoxy-D-glucose multiple interactions ISO Parp1 (Mus musculus) 6480464 Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]] CTD PMID:29095437 PARP1 Human 2-deoxy-D-glucose increases cleavage EXP 6480464 Deoxyglucose results in increased cleavage of PARP1 protein CTD PMID:25246272 PARP1 Human 2-hydroxyethyl methacrylate increases cleavage EXP 6480464 hydroxyethyl methacrylate results in increased cleavage of PARP1 protein CTD PMID:28184909 PARP1 Human 2-hydroxyethyl methacrylate multiple interactions EXP 6480464 3-(4-methylphenylsulfonyl)-2-propenenitrile inhibits the reaction [hydroxyethyl methacrylate results in increased cleavage of PARP1 protein] CTD PMID:28184909 PARP1 Human 2-methoxy-17beta-estradiol increases expression EXP 6480464 2-Methoxyestradiol results in increased expression of PARP1 protein modified form CTD PMID:23967052 PARP1 Human 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO Parp1 (Mus musculus) 6480464 6-methyl-2-(phenylethynyl)pyridine promotes the reaction [Oxidopamine results in increased cleavage of PARP1 protein] and GOPC protein affects the reaction [6-methyl-2-(phenylethynyl)pyridine promotes the reaction [Oxidopamine results in increased cleavage of PARP1 protein]] CTD PMID:33571554 PARP1 Human 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] CTD PMID:31423616 PARP1 Human 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions EXP 6480464 geranylgeranyl pyrophosphate inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] and geranylgeranyl pyrophosphate inhibits the reaction [TNFSF10 protein promotes the reaction [Simvastatin results in increased cleavage of PARP1 protein]] CTD PMID:21910007 PARP1 Human 20-hydroxyecdysone increases cleavage EXP 6480464 Ecdysterone results in increased cleavage of PARP1 protein CTD PMID:33878320 PARP1 Human 3'-O-(4-Benzoyl)benzoyl ATP increases expression ISO Parp1 (Mus musculus) 6480464 3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate results in increased expression of PARP1 protein CTD PMID:22253048 PARP1 Human 3,3',4,4',5-pentachlorobiphenyl multiple interactions EXP 6480464 3 more ... CTD PMID:20840854 PARP1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Parp1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 PARP1 Human 3,3',4,4',5-pentachlorobiphenyl increases activity EXP 6480464 3 more ... CTD PMID:16884709 PARP1 Human 3,3',4,4'-tetrachlorobiphenyl increases activity EXP 6480464 3 more ... CTD PMID:19433264 PARP1 Human 3,3',4,4'-tetrachlorobiphenyl multiple interactions EXP 6480464 [3 more ... CTD PMID:19433264 PARP1 Human 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of PARP1 protein CTD PMID:31675489 PARP1 Human 3,3'-diindolylmethane multiple interactions EXP 6480464 [3 and 3'-diindolylmethane co-treated with Paclitaxel] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:16580691 PARP1 Human 3,4-methylenedioxymethamphetamine increases expression ISO Parp1 (Mus musculus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PARP1 mRNA CTD PMID:20188158 PARP1 Human 3,4-methylenedioxymethamphetamine decreases cleavage ISO Parp1 (Rattus norvegicus) 6480464 N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased cleavage of PARP1 protein CTD PMID:26068050 PARP1 Human 3-(1H-indol-3-yl)propanoic acid increases cleavage EXP 6480464 indolepropionic acid analog results in increased cleavage of PARP1 protein CTD PMID:23499788 PARP1 Human 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions EXP 6480464 bisindolylmaleimide I inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] CTD PMID:16407847 PARP1 Human 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Parp1 (Mus musculus) 6480464 bisindolylmaleimide I inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein] CTD PMID:22155090 PARP1 Human 3-aminobenzamide multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Asbestos more ... CTD PMID:11217149 more ... PARP1 Human 3-aminobenzamide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-aminobenzamide inhibits the reaction [[sodium arsenite co-treated with lead acetate co-treated with Cadmium Chloride] results in increased cleavage of PARP1 protein] and 3-aminobenzamide inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:28283887 PARP1 Human 3-aminobenzamide decreases activity ISO Parp1 (Rattus norvegicus) 6480464 3-aminobenzamide results in decreased activity of PARP1 protein CTD PMID:18815186 PARP1 Human 3-aminobenzamide decreases activity ISO Parp1 (Mus musculus) 6480464 3-aminobenzamide results in decreased activity of PARP1 protein CTD PMID:27026705 PARP1 Human 3-aminobenzamide decreases activity EXP 6480464 3-aminobenzamide results in decreased activity of PARP1 protein CTD PMID:15075382 more ... PARP1 Human 3-aminobenzamide multiple interactions ISO Parp1 (Mus musculus) 6480464 3-aminobenzamide inhibits the reaction [PARP1 protein results in increased susceptibility to Acetaminophen] CTD PMID:15601672 PARP1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Parp1 (Mus musculus) 6480464 2 more ... CTD PMID:2523799 and PMID:29704545 PARP1 Human 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine increases cleavage EXP 6480464 2-amino-3-methylimidazo(4 and 5-f)quinoline results in increased cleavage of PARP1 protein CTD PMID:35985368 PARP1 Human 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [3 more ... CTD PMID:19116755 more ... PARP1 Human 3-methyladenine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [aristolochic acid I results in increased cleavage of PARP1 protein] and 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:23939141 and PMID:34374793 PARP1 Human 3-methyladenine multiple interactions ISO Parp1 (Mus musculus) 6480464 3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein] CTD PMID:19116755 PARP1 Human 3-methyladenine increases cleavage EXP 6480464 3-methyladenine results in increased cleavage of PARP1 protein CTD PMID:21616090 PARP1 Human 3-methylcholanthrene multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Methylcholanthrene inhibits the reaction [3-amino-1 more ... CTD PMID:11999409 PARP1 Human 3-Nitrofluoranthene increases cleavage ISO Parp1 (Mus musculus) 6480464 3-nitrofluoranthene results in increased cleavage of PARP1 protein CTD PMID:19041363 PARP1 Human 3-phenylprop-2-enal increases cleavage EXP 6480464 cinnamaldehyde analog results in increased cleavage of PARP1 protein CTD PMID:16343908 PARP1 Human 4'-epidoxorubicin increases cleavage ISO Parp1 (Mus musculus) 6480464 Epirubicin results in increased cleavage of PARP1 protein CTD PMID:26646421 PARP1 Human 4'-epidoxorubicin multiple interactions EXP 6480464 [Gossypol co-treated with Epirubicin] results in increased cleavage of PARP1 protein CTD PMID:35872041 PARP1 Human 4'-epidoxorubicin multiple interactions ISO Parp1 (Mus musculus) 6480464 paeonol inhibits the reaction [Epirubicin results in increased cleavage of PARP1 protein] CTD PMID:26646421 PARP1 Human 4,4'-diaminodiphenylmethane increases expression ISO Parp1 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of PARP1 mRNA CTD PMID:18648102 PARP1 Human 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions EXP 6480464 4 more ... CTD PMID:28343033 PARP1 Human 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of PARP1 protein CTD PMID:34186270 PARP1 Human 4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide increases degradation EXP 6480464 4-(4-chloro-2-methylphenoxy)-N-hydroxybutanamide results in increased degradation of PARP1 protein CTD PMID:20446019 PARP1 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one decreases expression EXP 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 mRNA and 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein CTD PMID:35435490 PARP1 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one multiple interactions EXP 6480464 NIPBL mRNA alternative form promotes the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in decreased expression of PARP1 protein] CTD PMID:35435490 PARP1 Human 4-amino-1,8-naphthalimide multiple interactions EXP 6480464 4-amino-1 and 8-naphthalimide inhibits the reaction [Doxorubicin results in increased activity of PARP1 protein] CTD PMID:15456408 PARP1 Human 4-amino-1,8-naphthalimide decreases expression EXP 6480464 4-amino-1 and 8-naphthalimide results in decreased expression of PARP1 protein CTD PMID:25499136 PARP1 Human 4-amino-1,8-naphthalimide multiple interactions ISO Parp1 (Mus musculus) 6480464 ATM protein affects the reaction [4-amino-1 more ... CTD PMID:16556909 PARP1 Human 4-amino-1,8-naphthalimide decreases activity ISO Parp1 (Mus musculus) 6480464 4-amino-1 and 8-naphthalimide results in decreased activity of PARP1 protein CTD PMID:16556909 PARP1 Human 4-amino-2,6-dinitrotoluene affects expression ISO Parp1 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of PARP1 mRNA CTD PMID:21346803 PARP1 Human 4-hydroxynon-2-enal increases degradation EXP 6480464 4-hydroxy-2-nonenal results in increased degradation of PARP1 protein CTD PMID:11488593 PARP1 Human 4-hydroxyphenyl retinamide multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] more ... CTD PMID:16230421 more ... PARP1 Human 4-hydroxyphenyl retinamide increases cleavage EXP 6480464 Fenretinide results in increased cleavage of PARP1 protein CTD PMID:15735044 more ... PARP1 Human 4-hydroxyphenyl retinamide decreases cleavage EXP 6480464 Fenretinide results in decreased cleavage of PARP1 protein CTD PMID:17159502 PARP1 Human 4-hydroxyphenyl retinamide affects expression EXP 6480464 Fenretinide affects the expression of PARP1 mRNA CTD PMID:16570282 PARP1 Human 4-Nerolidylcatechol increases cleavage EXP 6480464 4-nerolidylcatechol results in increased cleavage of PARP1 protein CTD PMID:32334110 PARP1 Human 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein] more ... CTD PMID:27634458 more ... PARP1 Human 4-phenylbutyric acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:34214594 PARP1 Human 4-phenylbutyric acid multiple interactions ISO Parp1 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of PARP1 protein modified form] and 4-phenylbutyric acid inhibits the reaction [Tunicamycin results in increased expression of PARP1 protein modified form] CTD PMID:27578021 and PMID:32407927 PARP1 Human 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 pyridoxal phosphate-6-azophenyl-2' and 4'-disulfonic acid inhibits the reaction [zinc chloride results in increased expression of PARP1 protein] CTD PMID:22253048 PARP1 Human 5,7-dihydroxy-4'-methoxyflavone increases expression EXP 6480464 acacetin results in increased expression of PARP1 protein CTD PMID:36740148 PARP1 Human 5-aminolevulinic acid multiple interactions EXP 6480464 FADD mutant form inhibits the reaction [Aminolevulinic Acid analog results in increased cleavage of PARP1 protein] CTD PMID:21138480 PARP1 Human 5-aminolevulinic acid increases cleavage EXP 6480464 Aminolevulinic Acid analog results in increased cleavage of PARP1 protein CTD PMID:21138480 PARP1 Human 5-aza-2'-deoxycytidine decreases methylation EXP 6480464 Decitabine results in decreased methylation of PARP1 gene CTD PMID:20123007 PARP1 Human 5-aza-2'-deoxycytidine decreases expression EXP 6480464 Decitabine results in decreased expression of PARP1 protein CTD PMID:32006662 PARP1 Human 5-aza-2'-deoxycytidine multiple interactions EXP 6480464 [Decitabine co-treated with Busulfan] results in increased cleavage of PARP1 protein more ... CTD PMID:18636160 more ... PARP1 Human 5-aza-2'-deoxycytidine increases cleavage EXP 6480464 Decitabine results in increased cleavage of PARP1 protein CTD PMID:23300844 PARP1 Human 5-azacytidine increases cleavage ISO Parp1 (Mus musculus) 6480464 Azacitidine results in increased cleavage of PARP1 protein CTD PMID:32278510 PARP1 Human 5-azacytidine multiple interactions ISO Parp1 (Mus musculus) 6480464 Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein] CTD PMID:32278510 PARP1 Human 5-fluorouracil multiple interactions EXP 6480464 3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein] more ... CTD PMID:15896711 more ... PARP1 Human 5-fluorouracil increases cleavage ISO Parp1 (Mus musculus) 6480464 Fluorouracil results in increased cleavage of PARP1 protein CTD PMID:32270916 PARP1 Human 5-fluorouracil affects expression EXP 6480464 Fluorouracil affects the expression of PARP1 mRNA CTD PMID:34151400 PARP1 Human 5-fluorouracil multiple interactions ISO Parp1 (Mus musculus) 6480464 3-methyladenine promotes the reaction [Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein] and Fluorouracil results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:19116755 PARP1 Human 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of PARP1 and Fluorouracil results in increased expression of PARP1 mRNA CTD PMID:11300326 and PMID:28599477 PARP1 Human 5-fluorouracil increases cleavage EXP 6480464 Fluorouracil results in increased cleavage of PARP1 protein CTD PMID:15996812 more ... PARP1 Human 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole increases cleavage EXP 6480464 Omeprazole results in increased cleavage of PARP1 protein CTD PMID:15461867 PARP1 Human 6-(cyclohexylmethoxy)-5-nitrosopyrimidine-2,4-diamine multiple interactions EXP 6480464 [4-cyclohexylmethoxy-5-nitrosopyrimidine-2 and 6-diamine co-treated with 1-(3-((2-(dimethylamino)ethyl)carbamoyl)phenyl)-3-(4-(bis(2-chloroethyl)amino)phenyl)urea] results in increased cleavage of PARP1 protein CTD PMID:26208482 PARP1 Human 6-aminonicotinamide multiple interactions EXP 6480464 6-Aminonicotinamide inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein] CTD PMID:25246272 PARP1 Human 6-bromoindirubin-3'-oxime multiple interactions EXP 6480464 6-bromoindirubin-3'-oxime promotes the reaction [Paraquat results in increased expression of PARP1 protein modified form] CTD PMID:28414160 PARP1 Human 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:24726431 PARP1 Human 7,12-dimethyltetraphene increases expression ISO Parp1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:23969067 PARP1 Human 7,12-dimethyltetraphene increases expression ISO Parp1 (Mus musculus) 6480464 9 more ... CTD PMID:25448685 PARP1 Human 7,12-dimethyltetraphene multiple interactions ISO Parp1 (Mus musculus) 6480464 9 more ... CTD PMID:25448685 PARP1 Human 7,12-dimethyltetraphene decreases expression ISO Parp1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:23969067 PARP1 Human 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions EXP 6480464 Uric Acid inhibits the reaction [sodium arsenite inhibits the reaction [PARP1 protein binds to Zinc]] and Uric Acid inhibits the reaction [sodium arsenite results in decreased activity of and results in increased nitrosation of PARP1 protein] CTD PMID:31152818 PARP1 Human 7-ketocholesterol increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 7-ketocholesterol results in increased cleavage of PARP1 protein CTD PMID:25845326 PARP1 Human 7-ketocholesterol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein] more ... CTD PMID:25845326 PARP1 Human 8-(4-chlorophenylthio)-cAMP multiple interactions EXP 6480464 [Acetylcysteine results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3' and 5'-AMP] which results in increased cleavage of PARP1 protein CTD PMID:38042493 PARP1 Human 9-cis-retinoic acid increases cleavage EXP 6480464 Alitretinoin results in increased cleavage of PARP1 protein CTD PMID:16449964 PARP1 Human [6]-Shogaol increases cleavage EXP 6480464 shogaol results in increased cleavage of PARP1 protein CTD PMID:18384088 and PMID:25619640 PARP1 Human [6]-Shogaol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] more ... CTD PMID:18384088 and PMID:25619640 PARP1 Human abexinostat multiple interactions EXP 6480464 [Bortezomib co-treated with abexinostat] results in increased activity of PARP1 protein and quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [abexinostat results in increased cleavage of PARP1 protein] CTD PMID:18042714 and PMID:19417023 PARP1 Human abexinostat increases cleavage EXP 6480464 abexinostat results in increased cleavage of PARP1 protein CTD PMID:18042714 PARP1 Human ABT-737 multiple interactions EXP 6480464 [[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of PARP1 protein more ... CTD PMID:28843007 and PMID:32802178 PARP1 Human acadesine multiple interactions EXP 6480464 acadesine promotes the reaction [Artesunate results in increased cleavage of PARP1 protein] CTD PMID:33002460 PARP1 Human acenaphthylene increases cleavage EXP 6480464 acenaphthylene results in increased cleavage of PARP1 protein CTD PMID:21132278 PARP1 Human acetaldehyde increases cleavage EXP 6480464 Acetaldehyde results in increased cleavage of PARP1 protein CTD PMID:35158046 PARP1 Human acetaldehyde multiple interactions EXP 6480464 Silybin inhibits the reaction [Acetaldehyde results in increased cleavage of PARP1 protein] more ... CTD PMID:35158046 PARP1 Human acetochlor increases cleavage EXP 6480464 acetochlor results in increased cleavage of PARP1 protein CTD PMID:25291404 PARP1 Human acetochlor multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [acetochlor results in increased cleavage of PARP1 protein] CTD PMID:25291404 PARP1 Human acetylleucyl-leucyl-norleucinal multiple interactions ISO Parp1 (Mus musculus) 6480464 acetylleucyl-leucyl-norleucinal inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] CTD PMID:29111403 PARP1 Human acetylsalicylic acid multiple interactions EXP 6480464 [Aspirin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein more ... CTD PMID:15481331 more ... PARP1 Human acetylsalicylic acid increases cleavage EXP 6480464 Aspirin results in increased cleavage of PARP1 protein CTD PMID:11228543 more ... PARP1 Human acifluorfen increases expression EXP 6480464 acifluorfen results in increased expression of PARP1 protein modified form CTD PMID:25944804 PARP1 Human aclacinomycin A affects activity EXP 6480464 Aclarubicin affects the activity of PARP1 protein CTD PMID:20399885 PARP1 Human acrolein increases cleavage EXP 6480464 Acrolein results in increased cleavage of PARP1 protein CTD PMID:19596284 and PMID:29964147 PARP1 Human acrolein increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Acrolein results in increased cleavage of PARP1 protein CTD PMID:31639409 PARP1 Human acrolein multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-(formylhydroxyamino)-2-(3-phenyl-1-propyl)butanoic acid (2 and 2-dimethyl-1-methylcarbamoyl-1-propyl)amide inhibits the reaction [Acrolein results in increased cleavage of PARP1 protein] CTD PMID:31639409 PARP1 Human acrolein multiple interactions EXP 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PARP1 mRNA more ... CTD PMID:29964147 and PMID:32699268 PARP1 Human acrylamide increases cleavage EXP 6480464 Acrylamide results in increased cleavage of PARP1 protein CTD PMID:27634458 PARP1 Human acrylamide increases expression ISO Parp1 (Mus musculus) 6480464 Acrylamide results in increased expression of PARP1 protein CTD PMID:36565847 PARP1 Human acrylamide multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein] and Acetylcysteine inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein] CTD PMID:27634458 PARP1 Human acrylonitrile multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Acrylonitrile results in increased cleavage of PARP1 protein] CTD PMID:20981856 PARP1 Human acrylonitrile increases cleavage EXP 6480464 Acrylonitrile results in increased cleavage of PARP1 protein CTD PMID:20981856 PARP1 Human actinomycin D multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of PARP1 protein more ... CTD PMID:14640974 more ... PARP1 Human actinomycin D multiple interactions ISO Parp1 (Mus musculus) 6480464 PLD2 protein inhibits the reaction [Dactinomycin results in increased cleavage of PARP1 protein] CTD PMID:14640974 PARP1 Human Aeroplysinin 1 increases cleavage EXP 6480464 aeroplysinin I results in increased cleavage of PARP1 protein CTD PMID:27120392 PARP1 Human aflatoxin B1 increases expression ISO Parp1 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of PARP1 mRNA CTD PMID:19770486 PARP1 Human aflatoxin B1 increases cleavage EXP 6480464 Aflatoxin B1 results in increased cleavage of PARP1 protein CTD PMID:34089297 PARP1 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of PARP1 gene CTD PMID:27153756 PARP1 Human aflatoxin B1 multiple interactions EXP 6480464 CYP2A13 protein promotes the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form] more ... CTD PMID:22743290 PARP1 Human aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PARP1 protein modified form CTD PMID:22743290 PARP1 Human Aflatoxin G1 increases expression EXP 6480464 aflatoxin G1 results in increased expression of PARP1 protein modified form CTD PMID:23907605 PARP1 Human aflatoxin M1 multiple interactions EXP 6480464 [Aflatoxin M1 co-treated with ochratoxin A] results in increased expression of PARP1 protein CTD PMID:34126166 PARP1 Human AH23848 multiple interactions EXP 6480464 [6-isopropoxy-9-oxoxanthene-2-carboxylic acid co-treated with AH 23848] results in increased cleavage of and results in increased activity of PARP1 protein CTD PMID:19407222 PARP1 Human alantolactone increases cleavage EXP 6480464 alantolactone results in increased cleavage of PARP1 protein CTD PMID:22721982 PARP1 Human alborixin increases cleavage EXP 6480464 alborixin results in increased cleavage of PARP1 protein CTD PMID:27378626 PARP1 Human aldehydo-D-glucosamine increases cleavage EXP 6480464 Glucosamine results in increased cleavage of PARP1 protein CTD PMID:16850161 PARP1 Human aldehydo-D-glucosamine multiple interactions EXP 6480464 pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] CTD PMID:16850161 PARP1 Human aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of PARP1 mRNA and Glucose results in increased expression of PARP1 protein modified form CTD PMID:22228707 more ... PARP1 Human aldehydo-D-glucose increases activity EXP 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:21031461 and PMID:27288104 PARP1 Human aldehydo-D-glucose increases acetylation EXP 6480464 Glucose results in increased acetylation of PARP1 protein CTD PMID:28478229 PARP1 Human aldehydo-D-glucose affects localization EXP 6480464 Glucose affects the localization of PARP1 protein CTD PMID:28478229 PARP1 Human aldehydo-D-glucose multiple interactions ISO Parp1 (Mus musculus) 6480464 Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form] and PARP1 protein affects the reaction [Glucose results in increased ADP-ribosylation of GAPDH protein] CTD PMID:14523042 and PMID:29095437 PARP1 Human aldehydo-D-glucose increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased cleavage of PARP1 protein CTD PMID:22524206 PARP1 Human aldehydo-D-glucose multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [INS1 protein co-treated with Glucose] results in increased activity of PARP1 protein more ... CTD PMID:18004065 more ... PARP1 Human aldehydo-D-glucose increases activity ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:18004065 PARP1 Human aldehydo-D-glucose decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in decreased expression of PARP1 mRNA and Glucose results in decreased expression of PARP1 protein CTD PMID:21818840 and PMID:37619648 PARP1 Human aldehydo-D-glucose multiple interactions EXP 6480464 [Glucose co-treated with Oxygen deficiency] results in increased activity of PARP1 protein more ... CTD PMID:14523042 more ... PARP1 Human alginic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 Alginic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:35066102 PARP1 Human Alisol B increases cleavage EXP 6480464 alisol B results in increased cleavage of PARP1 protein CTD PMID:20197400 PARP1 Human all-trans-acitretin increases activity EXP 6480464 Acitretin results in increased activity of PARP1 protein CTD PMID:18624760 PARP1 Human all-trans-retinal increases cleavage EXP 6480464 Retinaldehyde results in increased cleavage of PARP1 protein CTD PMID:25331497 PARP1 Human all-trans-retinoic acid multiple interactions EXP 6480464 [IDH1 protein affects the susceptibility to Tretinoin] which affects the cleavage of PARP1 protein more ... CTD PMID:16826196 more ... PARP1 Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of PARP1 mRNA CTD PMID:33167477 PARP1 Human all-trans-retinoic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 Tretinoin results in increased cleavage of PARP1 protein CTD PMID:21626648 and PMID:29767511 PARP1 Human all-trans-retinoic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 Tretinoin promotes the reaction [pevonedistat results in increased cleavage of and results in increased activity of PARP1 protein] CTD PMID:22110742 PARP1 Human all-trans-retinoic acid increases cleavage EXP 6480464 Tretinoin results in increased cleavage of PARP1 protein CTD PMID:14519626 and PMID:17387344 PARP1 Human allethrin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Allethrins results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:25072698 PARP1 Human alloxan increases degradation ISO Parp1 (Rattus norvegicus) 6480464 Alloxan results in increased degradation of PARP1 protein CTD PMID:21982801 PARP1 Human alloxan multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 D-Glucaric acid more ... CTD PMID:21982801 PARP1 Human alpha,alpha-trehalose multiple interactions EXP 6480464 Trehalose inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] and Trehalose promotes the reaction [ovatodiolide results in increased cleavage of PARP1 protein] CTD PMID:23011206 and PMID:38000454 PARP1 Human alpha-mangostin increases cleavage EXP 6480464 mangostin results in increased cleavage of PARP1 protein CTD PMID:23954321 PARP1 Human alpha-naphthoflavone increases cleavage ISO Parp1 (Mus musculus) 6480464 alpha-naphthoflavone results in increased cleavage of PARP1 protein CTD PMID:30508555 PARP1 Human alpha-pinene multiple interactions EXP 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PARP1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PARP1 mRNA CTD PMID:32699268 PARP1 Human alpinumisoflavone increases cleavage EXP 6480464 alpinumisoflavone results in increased cleavage of PARP1 protein CTD PMID:23850732 PARP1 Human alprazolam multiple interactions EXP 6480464 [Caffeine co-treated with Alprazolam] results in increased activity of PARP1 protein CTD PMID:19490937 PARP1 Human alvocidib multiple interactions EXP 6480464 [alvocidib co-treated with 7-hydroxystaurosporine] results in increased cleavage of PARP1 protein more ... CTD PMID:10430095 more ... PARP1 Human alvocidib increases cleavage EXP 6480464 alvocidib results in increased cleavage of PARP1 protein CTD PMID:12170773 more ... PARP1 Human AM-251 multiple interactions EXP 6480464 AM 251 inhibits the reaction [HU 211 results in increased cleavage of PARP1 protein] CTD PMID:19509271 PARP1 Human amiloride multiple interactions EXP 6480464 Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] and Okadaic Acid inhibits the reaction [Amiloride promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] CTD PMID:15607733 and PMID:16059913 PARP1 Human aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein] CTD PMID:33930484 PARP1 Human amiodarone multiple interactions EXP 6480464 [3-methyladenine co-treated with Amiodarone] results in increased cleavage of PARP1 protein and [TNFSF10 co-treated with Amiodarone] results in increased cleavage of PARP1 protein CTD PMID:21292685 and PMID:23912912 PARP1 Human ammonia affects response to substance ISO Parp1 (Rattus norvegicus) 6480464 PARP1 protein affects the susceptibility to Ammonia CTD PMID:15147502 PARP1 Human ammonium acetate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein] and Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein] CTD PMID:15147502 PARP1 Human ammonium acetate increases expression ISO Parp1 (Rattus norvegicus) 6480464 ammonium acetate results in increased expression of PARP1 protein CTD PMID:15147502 PARP1 Human ammonium chloride multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 (1 more ... CTD PMID:14535961 PARP1 Human ammonium chloride increases cleavage ISO Parp1 (Mus musculus) 6480464 Ammonium Chloride results in increased cleavage of PARP1 protein CTD PMID:31310755 PARP1 Human ammonium chloride affects expression ISO Parp1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of PARP1 mRNA CTD PMID:16483693 PARP1 Human ammonium chloride increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Ammonium Chloride results in increased cleavage of PARP1 protein CTD PMID:14535961 PARP1 Human amosite asbestos increases activity EXP 6480464 Asbestos and Amosite results in increased activity of PARP1 protein CTD PMID:11217149 PARP1 Human amosite asbestos multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Asbestos more ... CTD PMID:11217149 PARP1 Human amphetamine decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Amphetamine results in decreased expression of PARP1 mRNA CTD PMID:30779732 PARP1 Human anandamide increases cleavage EXP 6480464 anandamide results in increased cleavage of PARP1 protein CTD PMID:29441458 PARP1 Human andrographolide increases cleavage EXP 6480464 andrographolide results in increased cleavage of PARP1 protein CTD PMID:35917943 PARP1 Human anethole multiple interactions EXP 6480464 anethole inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein] CTD PMID:10871845 PARP1 Human anthocyanin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Anthocyanins inhibits the reaction [Streptozocin results in increased cleavage of PARP1 protein] CTD PMID:28856781 PARP1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [1 more ... CTD PMID:14724571 more ... PARP1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Parp1 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [3-dinitrobenzene results in increased cleavage of PARP1 protein] CTD PMID:19477251 PARP1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [[sodium arsenite co-treated with Cadmium Chloride co-treated with lead acetate] results in increased expression of PARP1 protein] more ... CTD PMID:17292878 more ... PARP1 Human Antimony trioxide increases cleavage EXP 6480464 antimony trioxide results in increased cleavage of PARP1 protein CTD PMID:16112521 PARP1 Human Antimony trioxide multiple interactions EXP 6480464 Glutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein] CTD PMID:16112521 PARP1 Human antimycin A increases cleavage EXP 6480464 Antimycin A results in increased cleavage of PARP1 protein CTD PMID:16237197 and PMID:32662599 PARP1 Human antimycin A multiple interactions EXP 6480464 [Antimycin A co-treated with Paraquat] results in increased cleavage of PARP1 protein and Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of PARP1 protein] CTD PMID:16237197 and PMID:32662599 PARP1 Human Antrocin increases cleavage EXP 6480464 antrocin results in increased cleavage of PARP1 protein CTD PMID:21158420 PARP1 Human apigenin multiple interactions ISO Parp1 (Mus musculus) 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein] more ... CTD PMID:20493918 and PMID:22155090 PARP1 Human apigenin increases cleavage EXP 6480464 Apigenin results in increased cleavage of PARP1 protein CTD PMID:24148603 PARP1 Human apigenin multiple interactions EXP 6480464 [Apigenin co-treated with 3-(4-methylphenylsulfonyl)-2-propenenitrile] results in increased cleavage of PARP1 protein more ... CTD PMID:24070738 more ... PARP1 Human apocynin multiple interactions ISO Parp1 (Mus musculus) 6480464 acetovanillone inhibits the reaction [AGT protein results in increased activity of PARP1 protein] and acetovanillone inhibits the reaction [zinc chloride results in increased activity of PARP1 protein] CTD PMID:15502880 and PMID:18509044 PARP1 Human apocynin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [polyethylene glycol-superoxide dismutase co-treated with acetovanillone] inhibits the reaction [EDN1 protein results in increased expression of and results in increased cleavage of PARP1 protein] CTD PMID:24932781 PARP1 Human apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [arsenite results in increased oxidation of PARP1 protein] and acetovanillone inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein] CTD PMID:29111459 and PMID:34798142 PARP1 Human arachidonic acid multiple interactions EXP 6480464 1 more ... CTD PMID:19540902 and PMID:30626086 PARP1 Human arachidonic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 Arachidonic Acid results in increased cleavage of PARP1 protein CTD PMID:10403056 PARP1 Human arachidonic acid increases cleavage EXP 6480464 Arachidonic Acid results in increased cleavage of PARP1 protein CTD PMID:19540902 and PMID:21132278 PARP1 Human arachidonyl-2'-chloroethylamide multiple interactions ISO Parp1 (Mus musculus) 6480464 arachidonyl-2-chloroethylamide inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:31256211 PARP1 Human aristolochic acid A increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 aristolochic acid I results in increased cleavage of PARP1 protein CTD PMID:23939141 PARP1 Human aristolochic acid A increases expression ISO Parp1 (Mus musculus) 6480464 aristolochic acid I results in increased expression of PARP1 protein modified form CTD PMID:26656393 PARP1 Human aristolochic acid A multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [aristolochic acid I results in increased cleavage of PARP1 protein] and ATG5 affects the reaction [aristolochic acid I results in increased cleavage of PARP1 protein] CTD PMID:23939141 PARP1 Human arjunolic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 arjunolic acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21420465 PARP1 Human Aroclor 1254 increases expression ISO Parp1 (Mus musculus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of PARP1 mRNA CTD PMID:25113976 PARP1 Human arsane multiple interactions EXP 6480464 [[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of PARP1 protein more ... CTD PMID:21332098 more ... PARP1 Human arsane multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in increased cleavage of PARP1 protein more ... CTD PMID:28903487 and PMID:31542844 PARP1 Human arsane increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Arsenic results in increased cleavage of PARP1 protein CTD PMID:28903487 PARP1 Human arsane decreases expression EXP 6480464 Arsenic results in decreased expression of PARP1 mRNA and Arsenic results in decreased expression of PARP1 protein CTD PMID:21332098 and PMID:35490796 PARP1 Human arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of PARP1 mRNA and Arsenic results in decreased expression of PARP1 protein CTD PMID:21332098 and PMID:35490796 PARP1 Human arsenic atom increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Arsenic results in increased cleavage of PARP1 protein CTD PMID:28903487 PARP1 Human arsenic atom multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [[sodium arsenite results in increased abundance of Arsenic] which co-treated with Zinc deficiency] results in increased cleavage of PARP1 protein more ... CTD PMID:28903487 and PMID:31542844 PARP1 Human arsenic atom multiple interactions EXP 6480464 [[ABT-737 co-treated with Benzo(a)pyrene] co-treated with [sodium arsenite results in increased abundance of Arsenic]] results in decreased cleavage of PARP1 protein more ... CTD PMID:21332098 more ... PARP1 Human arsenite(3-) multiple interactions EXP 6480464 [arsenite results in decreased activity of PARP1 protein] which affects the localization of AIFM1 protein more ... CTD PMID:18392098 more ... PARP1 Human arsenite(3-) increases oxidation EXP 6480464 arsenite results in increased oxidation of PARP1 protein CTD PMID:34798142 PARP1 Human arsenite(3-) increases cleavage ISO Parp1 (Mus musculus) 6480464 arsenite results in increased cleavage of PARP1 protein CTD PMID:23396362 and PMID:32980394 PARP1 Human arsenite(3-) multiple interactions ISO Parp1 (Mus musculus) 6480464 MIR190A affects the reaction [NFKB1 protein affects the reaction [arsenite results in increased cleavage of PARP1 protein]] more ... CTD PMID:23396362 and PMID:32980394 PARP1 Human arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of PARP1 protein CTD PMID:18392098 PARP1 Human arsenite(3-) increases cleavage EXP 6480464 arsenite results in increased cleavage of PARP1 protein CTD PMID:20083129 and PMID:22260869 PARP1 Human arsenite(3-) decreases activity EXP 6480464 arsenite results in decreased activity of PARP1 protein CTD PMID:17011244 more ... PARP1 Human arsenite(3-) affects response to substance EXP 6480464 PARP1 protein affects the susceptibility to arsenite CTD PMID:22387748 PARP1 Human arsenite(3-) decreases cleavage EXP 6480464 arsenite results in decreased cleavage of PARP1 protein CTD PMID:22387748 PARP1 Human arsenous acid increases expression ISO Parp1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of PARP1 protein CTD PMID:28391263 PARP1 Human arsenous acid increases cleavage ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:15761769 more ... PARP1 Human arsenous acid increases expression ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PARP1 protein modified form CTD PMID:29095437 PARP1 Human arsenous acid increases degradation EXP 6480464 Arsenic Trioxide results in increased degradation of PARP1 protein CTD PMID:16166054 PARP1 Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PARP1 protein CTD PMID:19695276 and PMID:25419056 PARP1 Human arsenous acid increases activity ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased activity of PARP1 protein CTD PMID:24157283 PARP1 Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of PARP1 protein and Arsenic Trioxide results in increased expression of PARP1 protein modified form CTD PMID:25972196 and PMID:27430728 PARP1 Human arsenous acid increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:24634002 and PMID:32096187 PARP1 Human arsenous acid affects localization EXP 6480464 Arsenic Trioxide affects the localization of PARP1 protein modified form CTD PMID:15131059 PARP1 Human arsenous acid increases activity EXP 6480464 Arsenic Trioxide results in increased activity of PARP1 protein CTD PMID:11304686 PARP1 Human arsenous acid multiple interactions EXP 6480464 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] more ... CTD PMID:12883035 more ... PARP1 Human arsenous acid increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:10382944 more ... PARP1 Human arsenous acid multiple interactions ISO Parp1 (Mus musculus) 6480464 [Genistein co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein more ... CTD PMID:21078540 more ... PARP1 Human arsenous acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] and salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein] CTD PMID:24634002 and PMID:28391263 PARP1 Human artesunate increases cleavage EXP 6480464 Artesunate results in increased cleavage of PARP1 protein CTD PMID:24704559 and PMID:33002460 PARP1 Human artesunate multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein] more ... CTD PMID:33002460 PARP1 Human ARV-825 increases cleavage EXP 6480464 ARV-825 results in increased cleavage of PARP1 protein CTD PMID:26051217 PARP1 Human asbestos multiple interactions EXP 6480464 Asbestos results in increased expression of and results in decreased activity of PARP1 protein CTD PMID:21543585 PARP1 Human asbestos increases expression EXP 6480464 Asbestos results in increased expression of PARP1 mRNA CTD PMID:21543585 PARP1 Human Aspidin increases expression EXP 6480464 aspidin BB results in increased expression of PARP1 protein modified form CTD PMID:23628508 PARP1 Human astilbin multiple interactions EXP 6480464 astilbin inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:29471006 PARP1 Human atorvastatin calcium multiple interactions EXP 6480464 2-tert-butylhydroquinone inhibits the reaction [Atorvastatin results in increased cleavage of PARP1 protein] more ... CTD PMID:18172863 more ... PARP1 Human atorvastatin calcium increases cleavage ISO Parp1 (Mus musculus) 6480464 Atorvastatin results in increased cleavage of PARP1 protein CTD PMID:20876807 PARP1 Human atorvastatin calcium multiple interactions ISO Parp1 (Mus musculus) 6480464 ATG5 mutant form promotes the reaction [Atorvastatin results in increased cleavage of PARP1 protein] CTD PMID:20876807 PARP1 Human atorvastatin calcium increases cleavage EXP 6480464 Atorvastatin results in increased cleavage of PARP1 protein CTD PMID:16470222 more ... PARP1 Human ATP increases expression ISO Parp1 (Mus musculus) 6480464 Adenosine Triphosphate results in increased expression of PARP1 protein CTD PMID:22253048 PARP1 Human ATP multiple interactions EXP 6480464 PARP1 mutant form inhibits the reaction [Cadmium results in decreased abundance of Adenosine Triphosphate] CTD PMID:21767558 PARP1 Human ATP multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 protein affects the reaction [pyrithione zinc results in decreased abundance of Adenosine Triphosphate] and PARP1 protein affects the reaction [Zinc results in decreased abundance of Adenosine Triphosphate] CTD PMID:17728843 and PMID:19809895 PARP1 Human Atranorin increases cleavage ISO Parp1 (Mus musculus) 6480464 atranorin results in increased cleavage of PARP1 protein CTD PMID:26969521 PARP1 Human atrazine multiple interactions ISO Parp1 (Mus musculus) 6480464 Melatonin inhibits the reaction [Atrazine results in increased cleavage of PARP1 protein] CTD PMID:25259610 PARP1 Human atrazine increases cleavage ISO Parp1 (Mus musculus) 6480464 Atrazine results in increased cleavage of PARP1 protein CTD PMID:25259610 PARP1 Human aucubin multiple interactions ISO Parp1 (Mus musculus) 6480464 aucubin inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:32504734 PARP1 Human auranofin decreases activity EXP 6480464 Auranofin results in decreased activity of PARP1 protein CTD PMID:21370912 PARP1 Human auranofin increases cleavage EXP 6480464 Auranofin results in increased cleavage of PARP1 protein CTD PMID:15159275 PARP1 Human aurantiamide acetate affects binding EXP 6480464 N-benzoylphenylalanylphenylalinol acetate binds to PARP1 protein CTD PMID:24876881 PARP1 Human Auriculasin multiple interactions EXP 6480464 [auriculasin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein and TNFRSF10B protein affects the reaction [[auriculasin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein] CTD PMID:30817944 PARP1 Human bafilomycin A1 multiple interactions EXP 6480464 [Cysteine Proteinase Inhibitors results in decreased activity of USP8 protein] promotes the reaction [bafilomycin A1 results in increased cleavage of PARP1 protein] more ... CTD PMID:20876807 more ... PARP1 Human bafilomycin A1 multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 bafilomycin A1 promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:34374793 PARP1 Human bafilomycin A1 increases cleavage ISO Parp1 (Mus musculus) 6480464 bafilomycin A1 results in increased cleavage of PARP1 protein CTD PMID:31310755 PARP1 Human bafilomycin A1 increases expression EXP 6480464 bafilomycin A1 results in increased expression of PARP1 protein modified form CTD PMID:28063998 PARP1 Human bafilomycin A1 increases cleavage EXP 6480464 bafilomycin A1 results in increased cleavage of PARP1 protein CTD PMID:21616090 more ... PARP1 Human bafilomycin A1 multiple interactions ISO Parp1 (Mus musculus) 6480464 bafilomycin A1 inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] CTD PMID:29111403 PARP1 Human BAPTA multiple interactions EXP 6480464 1 more ... CTD PMID:24752504 PARP1 Human BAPTA multiple interactions ISO Parp1 (Mus musculus) 6480464 1 more ... CTD PMID:29111403 PARP1 Human Bardoxolone methyl increases cleavage EXP 6480464 bardoxolone methyl results in increased cleavage of PARP1 protein CTD PMID:17363558 and PMID:25246272 PARP1 Human belinostat increases cleavage EXP 6480464 belinostat results in increased cleavage of PARP1 protein CTD PMID:18223231 and PMID:25537862 PARP1 Human belinostat increases expression ISO Parp1 (Mus musculus) 6480464 belinostat results in increased expression of PARP1 mRNA and belinostat results in increased expression of PARP1 protein CTD PMID:29733868 PARP1 Human belinostat multiple interactions EXP 6480464 Bortezomib promotes the reaction [belinostat results in increased cleavage of PARP1 protein] CTD PMID:18223231 PARP1 Human bellidifolin decreases expression EXP 6480464 bellidifolin results in decreased expression of PARP1 protein CTD PMID:33299414 PARP1 Human benomyl increases cleavage EXP 6480464 Benomyl results in increased cleavage of PARP1 protein CTD PMID:16903866 PARP1 Human benzalkonium chloride increases cleavage EXP 6480464 Benzalkonium Compounds analog results in increased cleavage of PARP1 protein CTD PMID:31982400 PARP1 Human benzalkonium chloride multiple interactions EXP 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Benzalkonium Compounds analog results in increased cleavage of PARP1 protein] CTD PMID:31982400 PARP1 Human benzamide multiple interactions EXP 6480464 [benzamide results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD] more ... CTD PMID:17669606 and PMID:19447888 PARP1 Human benzamide decreases activity EXP 6480464 benzamide results in decreased activity of PARP1 protein CTD PMID:17669606 and PMID:18695944 PARP1 Human benzamide decreases activity ISO Parp1 (Mus musculus) 6480464 benzamide results in decreased activity of PARP1 protein CTD PMID:11593040 PARP1 Human benzamide multiple interactions ISO Parp1 (Mus musculus) 6480464 [benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Hydrogen Peroxide more ... CTD PMID:11593040 PARP1 Human benzamide decreases expression ISO Parp1 (Mus musculus) 6480464 benzamide results in decreased expression of PARP1 protein CTD PMID:19998477 PARP1 Human benzamide decreases activity ISO Parp1 (Rattus norvegicus) 6480464 benzamide results in decreased activity of PARP1 protein CTD PMID:12411406 PARP1 Human benzatropine multiple interactions EXP 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein CTD PMID:34122009 PARP1 Human benzatropine decreases expression EXP 6480464 Benztropine results in decreased expression of PARP1 protein CTD PMID:34122009 PARP1 Human benzene increases cleavage EXP 6480464 Benzene analog results in increased cleavage of PARP1 protein CTD PMID:15826604 PARP1 Human benzene increases methylation EXP 6480464 Benzene results in increased methylation of PARP1 promoter CTD PMID:20230882 PARP1 Human benzene multiple interactions EXP 6480464 decitabine inhibits the reaction [Benzene results in decreased expression of PARP1 mRNA] more ... CTD PMID:20230882 PARP1 Human benzene decreases expression EXP 6480464 Benzene results in decreased expression of PARP1 mRNA CTD PMID:20230882 PARP1 Human benzo[a]pyrene multiple interactions ISO Parp1 (Mus musculus) 6480464 Benzo(a)pyrene promotes the reaction [AHR protein binds to PARP1 promoter] and Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] CTD PMID:19654925 and PMID:32061149 PARP1 Human benzo[a]pyrene decreases methylation ISO Parp1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased methylation of PARP1 exon and Benzo(a)pyrene results in decreased methylation of PARP1 intron CTD PMID:27901495 PARP1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of PARP1 promoter CTD PMID:27901495 PARP1 Human benzo[a]pyrene increases cleavage EXP 6480464 Benzo(a)pyrene results in increased cleavage of PARP1 protein CTD PMID:20840854 and PMID:24685774 PARP1 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of PARP1 protein CTD PMID:24664296 PARP1 Human benzo[a]pyrene multiple interactions EXP 6480464 2 more ... CTD PMID:20840854 more ... PARP1 Human benzo[a]pyrene increases cleavage ISO Parp1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased cleavage of PARP1 protein CTD PMID:19041363 and PMID:32061149 PARP1 Human benzo[a]pyrene decreases expression ISO Parp1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of PARP1 mRNA CTD PMID:19770486 PARP1 Human benzo[a]pyrene decreases response to substance EXP 6480464 PARP1 protein results in decreased susceptibility to Benzo(a)pyrene CTD PMID:19247804 PARP1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of PARP1 mRNA and Benzo(a)pyrene results in decreased expression of PARP1 protein CTD PMID:20064835 and PMID:33278487 PARP1 Human Benzo[a]pyrene-7,8-diol multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [benzo(a)pyrene 7 and 8-dihydrodiol results in increased cleavage of PARP1 protein] CTD PMID:15572374 PARP1 Human Benzo[a]pyrene-7,8-diol increases cleavage EXP 6480464 benzo(a)pyrene 7 and 8-dihydrodiol results in increased cleavage of PARP1 protein CTD PMID:15572374 PARP1 Human benzo[b]fluoranthene increases cleavage EXP 6480464 benzo(b)fluoranthene results in increased cleavage of PARP1 protein CTD PMID:21132278 PARP1 Human Benzo[ghi]perylene increases cleavage EXP 6480464 1 and 12-benzoperylene results in increased cleavage of PARP1 protein CTD PMID:21132278 PARP1 Human Benzo[k]fluoranthene increases cleavage EXP 6480464 benzo(k)fluoranthene results in increased cleavage of PARP1 protein CTD PMID:21132278 PARP1 Human benzoates increases cleavage EXP 6480464 Benzoates analog results in increased cleavage of PARP1 protein CTD PMID:29472718 PARP1 Human Benzoyl peroxide increases activity EXP 6480464 Benzoyl Peroxide results in increased activity of PARP1 protein CTD PMID:2120135 and PMID:2126186 PARP1 Human Benzoyl peroxide multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Benzoyl Peroxide results in increased activity of PARP1 protein] more ... CTD PMID:2120135 and PMID:2126186 PARP1 Human berberine increases cleavage EXP 6480464 Berberine results in increased cleavage of PARP1 protein CTD PMID:16505103 PARP1 Human berberine multiple interactions EXP 6480464 [Berberine co-treated with Cisplatin] results in increased cleavage of PARP1 protein more ... CTD PMID:26712469 and PMID:36070022 PARP1 Human beta-carboline increases cleavage EXP 6480464 norharman results in increased cleavage of PARP1 protein CTD PMID:35985368 PARP1 Human beta-cyclodextrin multiple interactions ISO Parp1 (Mus musculus) 6480464 betadex inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:11035063 PARP1 Human beta-D-glucosamine increases cleavage EXP 6480464 Glucosamine results in increased cleavage of PARP1 protein CTD PMID:16850161 PARP1 Human beta-D-glucosamine multiple interactions EXP 6480464 pepstatin inhibits the reaction [Glucosamine results in increased cleavage of PARP1 protein] CTD PMID:16850161 PARP1 Human beta-Elemonic acid increases cleavage EXP 6480464 beta-elemonic acid results in increased cleavage of PARP1 protein CTD PMID:33878321 PARP1 Human beta-ionone multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [beta-ionone results in increased cleavage of PARP1 protein] more ... CTD PMID:36843289 PARP1 Human beta-ionone increases cleavage EXP 6480464 beta-ionone results in increased cleavage of PARP1 protein CTD PMID:36843289 PARP1 Human betulin multiple interactions EXP 6480464 [betulin co-treated with Oxygen] results in increased cleavage of PARP1 protein more ... CTD PMID:26540049 more ... PARP1 Human betulin increases cleavage EXP 6480464 betulin results in increased cleavage of PARP1 protein CTD PMID:32190974 and PMID:33181113 PARP1 Human betulinic acid multiple interactions EXP 6480464 [Betulinic Acid co-treated with Oxygen] results in increased cleavage of PARP1 protein and Betulinic Acid promotes the reaction [Gefitinib results in increased cleavage of PARP1 protein] CTD PMID:30136359 and PMID:33181113 PARP1 Human betulinic acid increases expression EXP 6480464 Betulinic Acid results in increased expression of PARP1 protein modified form CTD PMID:26540049 PARP1 Human betulinic acid increases cleavage EXP 6480464 Betulinic Acid results in increased cleavage of PARP1 protein CTD PMID:30136359 and PMID:33181113 PARP1 Human bicalutamide multiple interactions EXP 6480464 bicalutamide promotes the reaction [Niclosamide results in increased expression of PARP1 protein modified form] CTD PMID:28500234 PARP1 Human bilirubin IXalpha increases expression EXP 6480464 Bilirubin results in increased expression of PARP1 protein modified form CTD PMID:27578021 PARP1 Human bilirubin IXalpha multiple interactions ISO Parp1 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Bilirubin results in increased expression of PARP1 protein modified form] CTD PMID:27578021 PARP1 Human biochanin A increases cleavage EXP 6480464 biochanin A results in increased cleavage of PARP1 protein CTD PMID:12791511 PARP1 Human bis(2-chloroethyl) sulfide multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [Mustard Gas results in increased cleavage of PARP1 protein] more ... CTD PMID:11886524 more ... PARP1 Human bis(2-chloroethyl) sulfide increases cleavage EXP 6480464 Mustard Gas results in increased cleavage of PARP1 protein CTD PMID:11886524 more ... PARP1 Human bis(2-chloroethyl) sulfide decreases expression EXP 6480464 Mustard Gas results in decreased expression of PARP1 mRNA CTD PMID:25102026 PARP1 Human bis(2-chloroethyl) sulfide increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Mustard Gas results in increased cleavage of PARP1 protein CTD PMID:20659490 PARP1 Human bis(2-chloroethyl) sulfide multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 protein inhibits the reaction [Mustard Gas results in increased activity of CASP3 protein] CTD PMID:11886524 PARP1 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Parp1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of PARP1 protein] and PRDX5 protein inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of PARP1 protein] CTD PMID:31408635 PARP1 Human bis(2-ethylhexyl) phthalate increases expression ISO Parp1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of PARP1 mRNA CTD PMID:36423848 PARP1 Human bis(2-ethylhexyl) phthalate increases cleavage ISO Parp1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased cleavage of PARP1 protein CTD PMID:31408635 PARP1 Human bisphenol A affects expression ISO Parp1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of PARP1 mRNA CTD PMID:25181051 PARP1 Human bisphenol A increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 bisphenol A results in increased cleavage of PARP1 protein CTD PMID:35567931 and PMID:35887390 PARP1 Human bisphenol A multiple interactions ISO Parp1 (Mus musculus) 6480464 bisphenol A promotes the reaction [Cholesterol results in increased cleavage of PARP1 protein] and Resveratrol inhibits the reaction [bisphenol A promotes the reaction [Cholesterol results in increased cleavage of PARP1 protein]] CTD PMID:33239236 PARP1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PARP1 protein CTD PMID:34186270 PARP1 Human bisphenol A multiple interactions EXP 6480464 bisphenol A results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:38372072 PARP1 Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of PARP1 mRNA CTD PMID:30903817 PARP1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PARP1 mRNA and bisphenol A results in decreased expression of PARP1 protein CTD PMID:29275510 more ... PARP1 Human bisphenol A decreases expression ISO Parp1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of PARP1 mRNA and bisphenol A results in decreased expression of PARP1 protein CTD PMID:27189055 and PMID:34947998 PARP1 Human bisphenol A increases methylation ISO Parp1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of PARP1 gene CTD PMID:28505145 PARP1 Human bisphenol A multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with tributyltin] results in increased expression of PARP1 mRNA and Genistein inhibits the reaction [bisphenol A results in decreased cleavage of PARP1 protein] CTD PMID:24884420 and PMID:31129395 PARP1 Human bisphenol A decreases cleavage ISO Parp1 (Rattus norvegicus) 6480464 bisphenol A results in decreased cleavage of PARP1 protein CTD PMID:24884420 PARP1 Human bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of PARP1 protein CTD PMID:34186270 PARP1 Human bleomycin A2 increases expression ISO Parp1 (Mus musculus) 6480464 Bleomycin results in increased expression of PARP1 protein CTD PMID:16317386 PARP1 Human bleomycin A2 multiple interactions ISO Parp1 (Mus musculus) 6480464 Bleomycin inhibits the reaction [Azacitidine results in increased cleavage of PARP1 protein] CTD PMID:32278510 PARP1 Human bleomycin A2 increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Bleomycin results in increased cleavage of PARP1 protein CTD PMID:15371238 PARP1 Human bortezomib multiple interactions EXP 6480464 [alvocidib co-treated with Bortezomib] results in increased cleavage of PARP1 protein more ... CTD PMID:12893773 more ... PARP1 Human bortezomib increases cleavage ISO Parp1 (Mus musculus) 6480464 Bortezomib results in increased cleavage of PARP1 protein CTD PMID:29384525 PARP1 Human bortezomib increases expression EXP 6480464 Bortezomib results in increased expression of PARP1 protein CTD PMID:17156654 PARP1 Human bortezomib increases cleavage EXP 6480464 Bortezomib results in increased cleavage of PARP1 protein CTD PMID:16617327 more ... PARP1 Human bosutinib multiple interactions EXP 6480464 [bosutinib co-treated with linsidomine] affects the expression of PARP1 protein and bosutinib affects the reaction [linsidomine results in increased cleavage of PARP1 protein] CTD PMID:34519134 PARP1 Human brassinin increases cleavage EXP 6480464 brassinin analog results in increased cleavage of PARP1 protein CTD PMID:24747292 PARP1 Human brazilin multiple interactions EXP 6480464 bafilomycin A1 promotes the reaction [brazilin results in increased expression of PARP1 protein modified form] and BECN1 inhibits the reaction [brazilin results in increased expression of PARP1 protein modified form] CTD PMID:28063998 PARP1 Human brazilin increases expression EXP 6480464 brazilin results in increased expression of PARP1 protein modified form CTD PMID:28063998 PARP1 Human brefeldin A multiple interactions ISO Parp1 (Mus musculus) 6480464 Apigenin inhibits the reaction [Brefeldin A results in increased cleavage of PARP1 protein] CTD PMID:20493918 PARP1 Human brefeldin A increases cleavage ISO Parp1 (Mus musculus) 6480464 Brefeldin A results in increased cleavage of PARP1 protein CTD PMID:20493918 PARP1 Human Brusatol increases cleavage EXP 6480464 brusatol results in increased cleavage of PARP1 protein CTD PMID:33465425 PARP1 Human bufalin multiple interactions EXP 6480464 HSPB1 protein inhibits the reaction [bufalin results in increased cleavage of PARP1 protein] CTD PMID:23091618 PARP1 Human bufalin increases cleavage EXP 6480464 bufalin results in increased cleavage of PARP1 protein CTD PMID:23091618 PARP1 Human busulfan multiple interactions EXP 6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased cleavage of PARP1 protein more ... CTD PMID:19732952 and PMID:20933509 PARP1 Human busulfan increases cleavage EXP 6480464 Busulfan results in increased cleavage of PARP1 protein CTD PMID:18339423 PARP1 Human butein increases cleavage EXP 6480464 butein results in increased cleavage of PARP1 protein CTD PMID:24931875 PARP1 Human butylated hydroxyanisole multiple interactions EXP 6480464 Butylated Hydroxyanisole inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] CTD PMID:16407847 PARP1 Human butyric acid increases cleavage EXP 6480464 Butyric Acid results in increased cleavage of PARP1 protein CTD PMID:27830268 PARP1 Human C.I. Natural Red 20 increases cleavage EXP 6480464 shikonin results in increased cleavage of PARP1 protein CTD PMID:24463199 and PMID:37268198 PARP1 Human C.I. Natural Red 20 multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein] CTD PMID:24463199 PARP1 Human cadmium atom increases cleavage ISO Parp1 (Mus musculus) 6480464 Cadmium results in increased cleavage of PARP1 protein CTD PMID:29111403 PARP1 Human cadmium atom increases cleavage EXP 6480464 Cadmium results in increased cleavage of PARP1 protein CTD PMID:28507149 more ... PARP1 Human cadmium atom increases expression ISO Parp1 (Mus musculus) 6480464 Cadmium results in increased expression of PARP1 mRNA CTD PMID:26187450 PARP1 Human cadmium atom increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Cadmium results in increased cleavage of PARP1 protein CTD PMID:19433269 more ... PARP1 Human cadmium atom multiple interactions EXP 6480464 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of PARP1 protein] more ... CTD PMID:21767558 more ... PARP1 Human cadmium atom multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] more ... CTD PMID:19433269 more ... PARP1 Human cadmium atom multiple interactions ISO Parp1 (Mus musculus) 6480464 1 more ... CTD PMID:29111403 more ... PARP1 Human cadmium dichloride multiple interactions ISO Parp1 (Mus musculus) 6480464 1 more ... CTD PMID:18850067 more ... PARP1 Human cadmium dichloride increases expression ISO Parp1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of PARP1 mRNA and Cadmium Chloride results in increased expression of PARP1 protein modified form CTD PMID:28283887 more ... PARP1 Human cadmium dichloride increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased cleavage of PARP1 protein CTD PMID:21544200 more ... PARP1 Human cadmium dichloride increases cleavage EXP 6480464 Cadmium Chloride results in increased cleavage of PARP1 protein CTD PMID:21544200 more ... PARP1 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PARP1 protein modified form CTD PMID:24291162 PARP1 Human cadmium dichloride affects cleavage ISO Parp1 (Mus musculus) 6480464 Cadmium Chloride affects the cleavage of PARP1 protein CTD PMID:18506790 PARP1 Human cadmium dichloride increases cleavage ISO Parp1 (Mus musculus) 6480464 Cadmium Chloride results in increased cleavage of PARP1 protein CTD PMID:18850067 and PMID:21420465 PARP1 Human cadmium dichloride multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 1 more ... CTD PMID:18703135 more ... PARP1 Human cadmium dichloride multiple interactions EXP 6480464 1 more ... CTD PMID:18703135 more ... PARP1 Human cadmium sulfate multiple interactions ISO Parp1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein] more ... CTD PMID:14687664 PARP1 Human cadmium sulfate increases cleavage ISO Parp1 (Mus musculus) 6480464 cadmium sulfate results in increased cleavage of PARP1 protein CTD PMID:14687664 PARP1 Human caffeine multiple interactions EXP 6480464 [Caffeine co-treated with Alprazolam] results in increased activity of PARP1 protein more ... CTD PMID:16522534 more ... PARP1 Human caffeine increases phosphorylation EXP 6480464 Caffeine results in increased phosphorylation of PARP1 protein CTD PMID:35688186 PARP1 Human caffeine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Caffeine inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] CTD PMID:30377735 PARP1 Human caffeine decreases response to substance EXP 6480464 PARP1 protein results in decreased susceptibility to Caffeine CTD PMID:21840268 PARP1 Human caffeine increases cleavage EXP 6480464 Caffeine results in increased cleavage of PARP1 protein CTD PMID:21229324 PARP1 Human caffeine affects cleavage EXP 6480464 Caffeine affects the cleavage of PARP1 protein CTD PMID:19242509 PARP1 Human calciol multiple interactions EXP 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein modified form more ... CTD PMID:22940495 PARP1 Human calciol affects expression EXP 6480464 Cholecalciferol affects the expression of PARP1 protein CTD PMID:18628207 PARP1 Human calcium atom multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 PARP1 Human calcium(0) multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 protein promotes the reaction [Hydrogen Peroxide results in increased uptake of Calcium] CTD PMID:20878536 PARP1 Human Calpeptin multiple interactions ISO Parp1 (Mus musculus) 6480464 calpeptin inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] CTD PMID:29111403 PARP1 Human Calpeptin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 calpeptin inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein] CTD PMID:25947082 PARP1 Human camptothecin multiple interactions EXP 6480464 6-chloro-2 more ... CTD PMID:15585644 more ... PARP1 Human camptothecin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin promotes the reaction [Camptothecin results in increased cleavage of PARP1 protein] CTD PMID:25843524 PARP1 Human camptothecin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Camptothecin results in increased cleavage of PARP1 protein CTD PMID:25843524 PARP1 Human camptothecin affects response to substance EXP 6480464 PARP1 protein affects the susceptibility to Camptothecin CTD PMID:27694308 and PMID:35778544 PARP1 Human camptothecin increases cleavage EXP 6480464 Camptothecin results in increased cleavage of PARP1 protein CTD PMID:11741290 more ... PARP1 Human camptothecin increases cleavage ISO Parp1 (Mus musculus) 6480464 Camptothecin results in increased cleavage of PARP1 protein CTD PMID:18506790 and PMID:29384525 PARP1 Human camptothecin multiple interactions ISO Parp1 (Mus musculus) 6480464 [Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein and [veliparib results in decreased activity of PARP1 protein] which results in increased susceptibility to Camptothecin CTD PMID:22158865 and PMID:25449198 PARP1 Human camptothecin decreases response to substance EXP 6480464 PARP1 results in decreased susceptibility to Camptothecin CTD PMID:27694308 PARP1 Human cannabidiol increases cleavage EXP 6480464 Cannabidiol results in increased cleavage of PARP1 protein CTD PMID:29441458 more ... PARP1 Human cannabidiol multiple interactions EXP 6480464 [Cannabidiol co-treated with moringin] results in decreased expression of PARP1 mRNA more ... CTD PMID:30096889 and PMID:31699976 PARP1 Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of PARP1 mRNA CTD PMID:33244087 PARP1 Human cantharidic acid increases cleavage EXP 6480464 cantharidic acid results in increased cleavage of PARP1 protein CTD PMID:29159945 more ... PARP1 Human cantharidin increases cleavage EXP 6480464 Cantharidin results in increased cleavage of PARP1 protein CTD PMID:27113412 PARP1 Human capillarisin increases cleavage EXP 6480464 capillarisin results in increased cleavage of PARP1 protein CTD PMID:24333736 PARP1 Human capillarisin multiple interactions EXP 6480464 Bortezomib promotes the reaction [capillarisin results in increased cleavage of PARP1 protein] more ... CTD PMID:24333736 PARP1 Human capsaicin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein] more ... CTD PMID:22200406 and PMID:22226932 PARP1 Human capsaicin increases cleavage ISO Parp1 (Mus musculus) 6480464 Capsaicin results in increased cleavage of PARP1 protein CTD PMID:17295509 PARP1 Human capsaicin increases expression EXP 6480464 Capsaicin results in increased expression of PARP1 protein CTD PMID:22226932 PARP1 Human capsaicin increases cleavage EXP 6480464 Capsaicin results in increased cleavage of PARP1 protein CTD PMID:17505005 and PMID:19855437 PARP1 Human capsaicin increases ADP-ribosylation EXP 6480464 Capsaicin results in increased ADP-ribosylation of PARP1 protein modified form CTD PMID:22226932 PARP1 Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of PARP1 mRNA CTD PMID:24752500 and PMID:25979313 PARP1 Human carbon nanotube increases cleavage ISO Parp1 (Mus musculus) 6480464 Nanotubes and Carbon results in increased cleavage of PARP1 protein CTD PMID:24929217 PARP1 Human carboplatin increases cleavage EXP 6480464 Carboplatin results in increased cleavage of PARP1 protein CTD PMID:15996812 PARP1 Human Cardamonin increases cleavage EXP 6480464 cardamonin results in increased cleavage of PARP1 protein CTD PMID:37268255 PARP1 Human carmustine multiple interactions EXP 6480464 Disulfiram promotes the reaction [Carmustine results in increased cleavage of PARP1 protein] CTD PMID:24193513 PARP1 Human carmustine increases cleavage EXP 6480464 Carmustine results in increased cleavage of PARP1 protein CTD PMID:24193513 PARP1 Human carnosic acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein] more ... CTD PMID:25446857 more ... PARP1 Human carnosic acid increases cleavage EXP 6480464 salvin results in increased cleavage of PARP1 protein CTD PMID:28918123 PARP1 Human carnosic acid decreases expression EXP 6480464 salvin results in decreased expression of PARP1 protein CTD PMID:28918123 PARP1 Human carnosic acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 salvin inhibits the reaction [Oxidopamine results in increased cleavage of PARP1 protein] CTD PMID:25446857 PARP1 Human carnosine multiple interactions EXP 6480464 Carnosine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 PARP1 Human Carnosol multiple interactions ISO Parp1 (Mus musculus) 6480464 carnosol inhibits the reaction [Dietary Fats results in increased expression of PARP1 protein modified form] more ... CTD PMID:34678374 PARP1 Human carteolol affects expression EXP 6480464 Carteolol affects the expression of PARP1 mRNA CTD PMID:37120125 PARP1 Human casticin increases expression ISO Parp1 (Mus musculus) 6480464 casticin results in increased expression of PARP1 protein CTD PMID:32270916 PARP1 Human CDP-choline decreases expression EXP 6480464 Cytidine Diphosphate Choline results in decreased expression of PARP1 protein modified form CTD PMID:12443983 PARP1 Human celastrol multiple interactions EXP 6480464 [TNFSF10 protein co-treated with celastrol] results in increased cleavage of PARP1 protein more ... CTD PMID:20605676 PARP1 Human celastrol increases cleavage EXP 6480464 celastrol results in increased cleavage of PARP1 protein CTD PMID:31715269 PARP1 Human celecoxib multiple interactions EXP 6480464 [Atorvastatin co-treated with Celecoxib] results in increased cleavage of PARP1 protein more ... CTD PMID:15572759 more ... PARP1 Human celecoxib multiple interactions ISO Parp1 (Mus musculus) 6480464 Celecoxib promotes the reaction [Dihematoporphyrin Ether results in increased cleavage of PARP1 protein] CTD PMID:16230411 PARP1 Human celecoxib increases cleavage EXP 6480464 Celecoxib results in increased cleavage of PARP1 protein CTD PMID:15572759 more ... PARP1 Human celecoxib increases activity EXP 6480464 Celecoxib results in increased activity of PARP1 protein CTD PMID:12824303 PARP1 Human celecoxib affects cleavage EXP 6480464 Celecoxib analog affects the cleavage of PARP1 protein CTD PMID:18485224 PARP1 Human cepharanthine decreases expression EXP 6480464 cepharanthine results in decreased expression of PARP1 protein CTD PMID:31255635 PARP1 Human cetylpyridinium increases cleavage EXP 6480464 Cetylpyridinium results in increased cleavage of PARP1 protein CTD PMID:31982400 PARP1 Human cetylpyridinium multiple interactions EXP 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Cetylpyridinium results in increased cleavage of PARP1 protein] CTD PMID:31982400 PARP1 Human chalcone increases cleavage EXP 6480464 Chalcone results in increased cleavage of PARP1 protein CTD PMID:20620131 PARP1 Human chalcone multiple interactions EXP 6480464 MYC protein affects the susceptibility to [Chalcone results in increased cleavage of PARP1 protein] CTD PMID:20620131 PARP1 Human chalcones multiple interactions EXP 6480464 BCL2 protein inhibits the reaction [Chalcones analog results in increased cleavage of PARP1 protein] CTD PMID:30576621 PARP1 Human chalcones increases cleavage EXP 6480464 Chalcones analog results in increased cleavage of PARP1 protein CTD PMID:30576621 PARP1 Human chenodeoxycholic acid multiple interactions EXP 6480464 [Chenodeoxycholic Acid co-treated with ursodoxicoltaurine] results in increased cleavage of PARP1 protein CTD PMID:14976352 PARP1 Human chenodeoxycholic acid increases cleavage EXP 6480464 Chenodeoxycholic Acid results in increased cleavage of PARP1 protein CTD PMID:14976352 PARP1 Human chloramphenicol multiple interactions EXP 6480464 CDKN1A mutant form inhibits the reaction [Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]] and Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein] CTD PMID:15905168 PARP1 Human chlordecone increases expression ISO Parp1 (Mus musculus) 6480464 Chlordecone results in increased expression of PARP1 mRNA CTD PMID:33711761 PARP1 Human chloroacetic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 chloroacetic acid results in increased cleavage of PARP1 protein CTD PMID:23103613 PARP1 Human chloropicrin multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [chloropicrin results in increased cleavage of PARP1 protein] CTD PMID:31884112 PARP1 Human chloropicrin increases cleavage EXP 6480464 chloropicrin results in increased cleavage of PARP1 protein CTD PMID:31884112 PARP1 Human chloroquine multiple interactions ISO Parp1 (Mus musculus) 6480464 Chloroquine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] CTD PMID:29111403 PARP1 Human chloroquine increases cleavage EXP 6480464 Chloroquine results in increased cleavage of PARP1 protein CTD PMID:28906492 more ... PARP1 Human chloroquine multiple interactions EXP 6480464 [Chloroquine co-treated with 3-methyladenine] results in increased cleavage of PARP1 protein more ... CTD PMID:28906492 more ... PARP1 Human chloroquine increases cleavage ISO Parp1 (Mus musculus) 6480464 Chloroquine results in increased cleavage of PARP1 protein CTD PMID:31310755 PARP1 Human chloroquine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Chloroquine promotes the reaction [Cadmium results in increased cleavage of PARP1 protein] and Chloroquine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:27658547 and PMID:34374793 PARP1 Human chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of PARP1 mRNA more ... CTD PMID:23416140 and PMID:28887667 PARP1 Human chlorpyrifos increases cleavage ISO Parp1 (Mus musculus) 6480464 Chlorpyrifos results in increased cleavage of PARP1 protein CTD PMID:34289071 and PMID:36252918 PARP1 Human chlorpyrifos increases expression ISO Parp1 (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of PARP1 mRNA and Chlorpyrifos results in increased expression of PARP1 protein CTD PMID:33908150 PARP1 Human chlorpyrifos increases cleavage EXP 6480464 Chlorpyrifos results in increased cleavage of PARP1 protein CTD PMID:24793810 PARP1 Human chlorpyrifos increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Chlorpyrifos results in increased cleavage of PARP1 protein CTD PMID:22714038 and PMID:29859868 PARP1 Human chlorpyrifos multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Hesperidin co-treated with Chlorpyrifos] results in increased expression of PARP1 mRNA more ... CTD PMID:22714038 more ... PARP1 Human cholesterol multiple interactions ISO Parp1 (Mus musculus) 6480464 bisphenol A promotes the reaction [Cholesterol results in increased cleavage of PARP1 protein] and Resveratrol inhibits the reaction [bisphenol A promotes the reaction [Cholesterol results in increased cleavage of PARP1 protein]] CTD PMID:33239236 PARP1 Human cholesterol increases cleavage ISO Parp1 (Mus musculus) 6480464 Cholesterol results in increased cleavage of PARP1 protein CTD PMID:33239236 PARP1 Human chromium atom increases cleavage ISO Parp1 (Mus musculus) 6480464 Chromium results in increased cleavage of PARP1 protein CTD PMID:12423593 PARP1 Human chromium atom multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human chromium(6+) multiple interactions EXP 6480464 Ascorbic Acid promotes the reaction [chromium hexavalent ion results in increased cleavage of PARP1 protein] more ... CTD PMID:15831465 more ... PARP1 Human chromium(6+) affects expression ISO Parp1 (Mus musculus) 6480464 chromium hexavalent ion affects the expression of PARP1 mRNA CTD PMID:28472532 PARP1 Human chromium(6+) increases cleavage EXP 6480464 chromium hexavalent ion results in increased cleavage of PARP1 protein CTD PMID:15831465 more ... PARP1 Human chromone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [4-chromone analog results in increased expression of PARP1 protein modified form] and benzyloxycarbonyl-valyl-alanyl-aspartyl-fluoromethane inhibits the reaction [4-chromone analog results in increased expression of PARP1 protein modified form] CTD PMID:30256521 PARP1 Human chromone increases expression EXP 6480464 4-chromone analog results in increased expression of PARP1 protein modified form CTD PMID:30256521 PARP1 Human chrysin multiple interactions EXP 6480464 [Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein and benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [[Cisplatin co-treated with chrysin] results in increased cleavage of PARP1 protein] CTD PMID:25770930 PARP1 Human chrysin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 chrysin inhibits the reaction [Cyclophosphamide results in increased expression of PARP1 protein] CTD PMID:37263553 PARP1 Human chrysin increases cleavage EXP 6480464 chrysin results in increased cleavage of PARP1 protein CTD PMID:18455702 and PMID:25770930 PARP1 Human ciglitazone multiple interactions EXP 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [ciglitazone promotes the reaction [Niflumic Acid results in increased cleavage of PARP1 protein]] more ... CTD PMID:15492468 and PMID:21067863 PARP1 Human ciglitazone increases cleavage EXP 6480464 ciglitazone results in increased cleavage of PARP1 protein CTD PMID:21067863 PARP1 Human cinchocaine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Dibucaine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein] CTD PMID:25947082 PARP1 Human Cinobufagin increases expression EXP 6480464 cinobufagin results in increased expression of PARP1 protein modified form CTD PMID:23164673 PARP1 Human Cinobufagin multiple interactions EXP 6480464 GSK3B protein mutant form inhibits the reaction [cinobufagin results in increased expression of PARP1 protein modified form] and SB 216763 promotes the reaction [cinobufagin results in increased expression of PARP1 protein modified form] CTD PMID:23164673 PARP1 Human ciprofloxacin increases cleavage EXP 6480464 Ciprofloxacin results in increased cleavage of PARP1 protein CTD PMID:10741713 PARP1 Human cisplatin multiple interactions EXP 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [FAM168A results in decreased susceptibility to Cisplatin]] which results in increased cleavage of PARP1 protein more ... CTD PMID:15496615 more ... PARP1 Human cisplatin increases expression ISO Parp1 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of PARP1 protein CTD PMID:29599129 PARP1 Human cisplatin increases activity ISO Parp1 (Mus musculus) 6480464 Cisplatin results in increased activity of PARP1 protein CTD PMID:25806124 PARP1 Human cisplatin increases activity EXP 6480464 Cisplatin results in increased activity of PARP1 protein CTD PMID:18468580 and PMID:25806124 PARP1 Human cisplatin increases expression ISO Parp1 (Mus musculus) 6480464 Cisplatin results in increased expression of PARP1 protein CTD PMID:26723870 and PMID:36178099 PARP1 Human cisplatin increases cleavage EXP 127284886 cisplatin increases cleavage of PARP1 protein in stomach RGD PARP1 Human cisplatin multiple interactions ISO Parp1 (Mus musculus) 6480464 [Nicotinamide Mononucleotide co-treated with Cisplatin] results in decreased expression of PARP1 protein more ... CTD PMID:24560772 more ... PARP1 Human cisplatin increases cleavage EXP 6480464 Cisplatin results in increased cleavage of PARP1 protein CTD PMID:15496615 more ... PARP1 Human cisplatin decreases response to substance EXP 6480464 PARP1 protein results in decreased susceptibility to Cisplatin CTD PMID:20798217 and PMID:21447800 PARP1 Human cisplatin decreases activity EXP 6480464 Cisplatin results in decreased activity of PARP1 protein CTD PMID:21370912 PARP1 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PARP1 protein and Cisplatin results in increased expression of PARP1 protein modified form CTD PMID:21274007 more ... PARP1 Human cisplatin increases cleavage ISO Parp1 (Mus musculus) 6480464 Cisplatin results in increased cleavage of PARP1 protein CTD PMID:23628706 more ... PARP1 Human cisplatin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Cisplatin results in increased cleavage of PARP1 protein CTD PMID:23628706 more ... PARP1 Human cisplatin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 5-aminoisoquinoline inhibits the reaction [Cisplatin results in increased expression of PARP1 protein] more ... CTD PMID:24973089 more ... PARP1 Human citalopram increases cleavage EXP 6480464 Citalopram results in increased cleavage of PARP1 protein CTD PMID:10487422 PARP1 Human cladribine multiple interactions EXP 6480464 [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein and [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein CTD PMID:15582267 PARP1 Human cladribine increases cleavage EXP 6480464 Cladribine results in increased cleavage of PARP1 protein CTD PMID:15582267 and PMID:21679466 PARP1 Human clobetasol decreases expression ISO Parp1 (Mus musculus) 6480464 Clobetasol results in decreased expression of PARP1 mRNA CTD PMID:27462272 PARP1 Human clofarabine multiple interactions EXP 6480464 [clofarabine co-treated with fludarabine co-treated with Busulfan] results in increased cleavage of PARP1 protein more ... CTD PMID:20933509 more ... PARP1 Human clofibric acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PARP1 mRNA CTD PMID:17602206 PARP1 Human clomipramine increases cleavage EXP 6480464 Clomipramine results in increased cleavage of PARP1 protein CTD PMID:10487422 PARP1 Human cobalt atom increases cleavage ISO Parp1 (Mus musculus) 6480464 Cobalt results in increased cleavage of PARP1 protein CTD PMID:12423593 PARP1 Human cobalt atom affects binding EXP 6480464 PARP1 protein modified form binds to Cobalt CTD PMID:25549802 PARP1 Human cobalt dichloride multiple interactions EXP 6480464 [Chromium Alloys co-treated with cobaltous chloride] results in increased cleavage of PARP1 protein more ... CTD PMID:19714248 more ... PARP1 Human cobalt dichloride increases cleavage EXP 6480464 cobaltous chloride results in increased cleavage of PARP1 protein CTD PMID:21882223 and PMID:22172632 PARP1 Human cobalt dichloride increases activity EXP 6480464 cobaltous chloride results in increased activity of PARP1 protein CTD PMID:25125499 PARP1 Human cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of PARP1 mRNA CTD PMID:19320972 PARP1 Human cobimetinib multiple interactions EXP 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:22084396 PARP1 Human cobimetinib increases cleavage EXP 6480464 cobimetinib results in increased cleavage of PARP1 protein CTD PMID:22084396 PARP1 Human cocaine affects expression ISO Parp1 (Mus musculus) 6480464 Cocaine affects the expression of PARP1 mRNA CTD PMID:15681117 PARP1 Human cocaine increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Cocaine results in increased cleavage of PARP1 protein CTD PMID:17084983 PARP1 Human colforsin daropate hydrochloride multiple interactions EXP 6480464 [Colforsin co-treated with Theophylline] inhibits the reaction [Etoposide results in increased cleavage of PARP1 protein] CTD PMID:9454737 PARP1 Human colforsin daropate hydrochloride increases cleavage EXP 6480464 Colforsin results in increased cleavage of PARP1 protein CTD PMID:31278978 PARP1 Human colistin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Colistin co-treated with Anisomycin] results in increased cleavage of PARP1 protein CTD PMID:28842171 PARP1 Human concanamycin A multiple interactions EXP 6480464 [lapatinib co-treated with concanamycin A] results in increased cleavage of PARP1 protein CTD PMID:25981168 PARP1 Human copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PARP1 mRNA more ... CTD PMID:17079463 more ... PARP1 Human copper atom multiple interactions ISO Parp1 (Mus musculus) 6480464 [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein CTD PMID:24690739 PARP1 Human copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in decreased expression of PARP1 mRNA more ... CTD PMID:17079463 more ... PARP1 Human copper(0) multiple interactions ISO Parp1 (Mus musculus) 6480464 [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein CTD PMID:24690739 PARP1 Human copper(II) chloride multiple interactions EXP 6480464 [Disulfiram co-treated with cupric chloride] results in increased cleavage of PARP1 protein and [prolinedithiocarbamate analog co-treated with cupric chloride] results in increased cleavage of PARP1 protein CTD PMID:19789329 and PMID:21035945 PARP1 Human copper(II) chloride increases expression ISO Parp1 (Mus musculus) 6480464 cupric chloride results in increased expression of PARP1 protein CTD PMID:23313662 PARP1 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of PARP1 mRNA CTD PMID:19549813 PARP1 Human cordycepin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cordycepin results in increased cleavage of PARP1 protein] more ... CTD PMID:24704558 PARP1 Human cordycepin increases cleavage ISO Parp1 (Mus musculus) 6480464 cordycepin results in increased cleavage of PARP1 protein CTD PMID:26303320 PARP1 Human cordycepin increases cleavage EXP 6480464 cordycepin results in increased cleavage of PARP1 protein CTD PMID:21196698 more ... PARP1 Human cordycepin multiple interactions EXP 6480464 cordycepin inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein] CTD PMID:21607289 PARP1 Human cordycepin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 cordycepin results in increased cleavage of PARP1 protein CTD PMID:24704558 PARP1 Human coumarin decreases activity EXP 6480464 coumarin results in decreased activity of PARP1 protein CTD PMID:17669606 PARP1 Human coumarin decreases expression EXP 6480464 coumarin analog results in decreased expression of PARP1 mRNA CTD PMID:32578917 PARP1 Human coumarin increases cleavage EXP 6480464 coumarin analog results in increased cleavage of PARP1 protein CTD PMID:31199928 PARP1 Human coumarin multiple interactions EXP 6480464 [coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NAD] and [coumarin results in decreased activity of PARP1 protein] inhibits the reaction [Tetrachlorodibenzodioxin results in decreased abundance of NADP] CTD PMID:17669606 PARP1 Human coumarins increases cleavage EXP 6480464 Coumarins analog results in increased cleavage of PARP1 protein CTD PMID:25231984 PARP1 Human coumestrol multiple interactions EXP 6480464 [Coumestrol co-treated with 2 more ... CTD PMID:19167446 PARP1 Human crizotinib increases cleavage EXP 6480464 Crizotinib results in increased cleavage of PARP1 protein CTD PMID:31639374 and PMID:31706006 PARP1 Human crizotinib multiple interactions EXP 6480464 benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [Crizotinib results in increased cleavage of PARP1 protein] CTD PMID:31706006 PARP1 Human crocidolite asbestos multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Asbestos more ... CTD PMID:20616036 and PMID:21543585 PARP1 Human crocidolite asbestos decreases expression EXP 6480464 Asbestos more ... CTD PMID:32006662 PARP1 Human crocidolite asbestos increases expression EXP 6480464 Asbestos and Crocidolite results in increased expression of PARP1 mRNA CTD PMID:20616036 PARP1 Human crocidolite asbestos increases cleavage EXP 6480464 Asbestos and Crocidolite results in increased cleavage of PARP1 protein CTD PMID:17191120 and PMID:19783790 PARP1 Human crocin-1 increases cleavage EXP 6480464 crocin results in increased cleavage of PARP1 protein CTD PMID:30672053 PARP1 Human crocin-1 multiple interactions EXP 6480464 MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein] CTD PMID:30672053 PARP1 Human Cryptotanshinone increases cleavage EXP 6480464 cryptotanshinone results in increased cleavage of PARP1 protein CTD PMID:26564229 PARP1 Human crystal violet increases cleavage EXP 6480464 Gentian Violet results in increased cleavage of PARP1 protein CTD PMID:24535435 PARP1 Human cucurbitacin E multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein] and Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein] CTD PMID:27106530 PARP1 Human cucurbitacin E increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 cucurbitacin E results in increased cleavage of PARP1 protein CTD PMID:27363783 PARP1 Human cucurbitacin E increases cleavage EXP 6480464 cucurbitacin E results in increased cleavage of PARP1 protein CTD PMID:27106530 PARP1 Human cucurbitacin I increases cleavage EXP 6480464 cucurbitacin I results in increased cleavage of PARP1 protein CTD PMID:24858077 PARP1 Human Cuprizon multiple interactions EXP 6480464 [Cuprizone co-treated with Benztropine] results in increased expression of PARP1 protein CTD PMID:34122009 PARP1 Human curcumin multiple interactions EXP 6480464 [Curcumin co-treated with Bortezomib] results in increased cleavage of PARP1 protein more ... CTD PMID:14724571 more ... PARP1 Human curcumin increases expression EXP 6480464 Curcumin results in increased expression of PARP1 protein modified form CTD PMID:27430728 PARP1 Human curcumin decreases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Curcumin results in decreased cleavage of PARP1 protein CTD PMID:26612707 PARP1 Human curcumin decreases expression EXP 6480464 Curcumin analog results in decreased expression of PARP1 mRNA CTD PMID:26409325 PARP1 Human curcumin increases cleavage EXP 6480464 Curcumin results in increased cleavage of PARP1 protein CTD PMID:14555224 more ... PARP1 Human curcumin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 carboxymethyl-chitosan analog promotes the reaction [Curcumin results in decreased cleavage of PARP1 protein] more ... CTD PMID:15569404 more ... PARP1 Human curcumin multiple interactions ISO Parp1 (Mus musculus) 6480464 [Doxorubicin co-treated with Curcumin] results in increased cleavage of PARP1 protein more ... CTD PMID:11035063 more ... PARP1 Human curcumin increases cleavage ISO Parp1 (Mus musculus) 6480464 Curcumin results in increased cleavage of PARP1 protein CTD PMID:21594647 PARP1 Human curcumin increases degradation EXP 6480464 Curcumin results in increased degradation of PARP1 CTD PMID:21595920 PARP1 Human CX-5461 increases cleavage EXP 6480464 CX 5461 results in increased cleavage of PARP1 protein CTD PMID:32799625 PARP1 Human cycloheximide multiple interactions EXP 6480464 [Cycloheximide co-treated with TNF protein] results in increased cleavage of PARP1 protein more ... CTD PMID:12925536 and PMID:18222423 PARP1 Human cycloheximide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein] CTD PMID:15147502 PARP1 Human cycloheximide increases cleavage EXP 6480464 Cycloheximide results in increased cleavage of PARP1 protein CTD PMID:16051428 PARP1 Human cyclophosphamide multiple interactions EXP 6480464 [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein and [Cladribine co-treated with Cyclophosphamide] results in decreased expression of PARP1 protein CTD PMID:15582267 PARP1 Human cyclophosphamide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 chrysin inhibits the reaction [Cyclophosphamide results in increased expression of PARP1 protein] CTD PMID:37263553 PARP1 Human cyclophosphamide increases expression ISO Parp1 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of PARP1 mRNA and Cyclophosphamide results in increased expression of PARP1 protein CTD PMID:11599041 and PMID:37263553 PARP1 Human cyclophosphamide increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased cleavage of PARP1 protein CTD PMID:11723234 PARP1 Human cyclophosphamide increases cleavage EXP 6480464 Cyclophosphamide results in increased cleavage of PARP1 protein CTD PMID:17898787 PARP1 Human cyclophosphamide decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Cyclophosphamide results in decreased expression of PARP1 mRNA CTD PMID:11906922 PARP1 Human cyclosporin A increases cleavage EXP 6480464 Cyclosporine results in increased cleavage of PARP1 protein CTD PMID:22155090 PARP1 Human cyclosporin A multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Cyclosporine inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein] CTD PMID:25947082 PARP1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of PARP1 mRNA CTD PMID:25562108 PARP1 Human cyclosporin A increases cleavage ISO Parp1 (Mus musculus) 6480464 Cyclosporine results in increased cleavage of PARP1 protein CTD PMID:22155090 PARP1 Human cyclosporin A multiple interactions ISO Parp1 (Mus musculus) 6480464 2-dimethylamino-4 more ... CTD PMID:22155090 PARP1 Human cyclosporin A multiple interactions EXP 6480464 salubrinal inhibits the reaction [Cyclosporine results in increased cleavage of PARP1 protein] CTD PMID:22155090 PARP1 Human cylindrospermopsin increases cleavage EXP 6480464 cylindrospermopsin results in increased cleavage of PARP1 protein CTD PMID:30500929 PARP1 Human cypermethrin multiple interactions EXP 6480464 cypermethrin inhibits the reaction [Docosahexaenoic Acids results in increased degradation of PARP1 protein] CTD PMID:11341974 PARP1 Human cypermethrin decreases expression EXP 6480464 cypermethrin results in decreased expression of PARP1 mRNA CTD PMID:27704156 PARP1 Human cytarabine multiple interactions EXP 6480464 [Cytarabine co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein more ... CTD PMID:12780785 and PMID:8840993 PARP1 Human cytarabine increases degradation EXP 6480464 Cytarabine results in increased degradation of PARP1 protein CTD PMID:8840993 PARP1 Human D-cycloserine multiple interactions EXP 6480464 Cycloserine inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 PARP1 Human D-glucose multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [INS1 protein co-treated with Glucose] results in increased activity of PARP1 protein more ... CTD PMID:18004065 more ... PARP1 Human D-glucose increases acetylation EXP 6480464 Glucose results in increased acetylation of PARP1 protein CTD PMID:28478229 PARP1 Human D-glucose multiple interactions ISO Parp1 (Mus musculus) 6480464 Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form] and PARP1 protein affects the reaction [Glucose results in increased ADP-ribosylation of GAPDH protein] CTD PMID:14523042 and PMID:29095437 PARP1 Human D-glucose increases activity EXP 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:21031461 and PMID:27288104 PARP1 Human D-glucose affects localization EXP 6480464 Glucose affects the localization of PARP1 protein CTD PMID:28478229 PARP1 Human D-glucose increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased cleavage of PARP1 protein CTD PMID:22524206 PARP1 Human D-glucose decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in decreased expression of PARP1 mRNA and Glucose results in decreased expression of PARP1 protein CTD PMID:21818840 and PMID:37619648 PARP1 Human D-glucose increases activity ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:18004065 PARP1 Human D-glucose increases expression EXP 6480464 Glucose results in increased expression of PARP1 mRNA and Glucose results in increased expression of PARP1 protein modified form CTD PMID:22228707 more ... PARP1 Human D-glucose multiple interactions EXP 6480464 [Glucose co-treated with Oxygen deficiency] results in increased activity of PARP1 protein more ... CTD PMID:14523042 more ... PARP1 Human D-penicillamine increases cleavage EXP 6480464 Penicillamine results in increased cleavage of PARP1 protein CTD PMID:22843330 PARP1 Human dactolisib increases cleavage EXP 6480464 dactolisib results in increased cleavage of PARP1 protein CTD PMID:21464613 PARP1 Human daidzein increases cleavage EXP 6480464 daidzein results in increased cleavage of PARP1 protein CTD PMID:12791511 PARP1 Human daunorubicin multiple interactions EXP 6480464 [Daunorubicin co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein CTD PMID:12780785 PARP1 Human daunorubicin affects expression EXP 6480464 Daunorubicin affects the expression of PARP1 mRNA CTD PMID:27780733 PARP1 Human daunorubicin increases cleavage EXP 6480464 Daunorubicin results in increased cleavage of PARP1 protein CTD PMID:10766178 more ... PARP1 Human DDE increases activity EXP 6480464 Dichlorodiphenyl Dichloroethylene results in increased activity of PARP1 protein CTD PMID:19545618 PARP1 Human decabromodiphenyl ether decreases expression EXP 6480464 decabromobiphenyl ether results in decreased expression of PARP1 protein CTD PMID:31675489 PARP1 Human Decursin increases cleavage EXP 6480464 decursin results in increased cleavage of PARP1 protein CTD PMID:17723170 PARP1 Human deguelin increases expression EXP 6480464 deguelin metabolite results in increased expression of PARP1 protein modified form and deguelin results in increased expression of PARP1 protein modified form CTD PMID:19139008 PARP1 Human deguelin increases cleavage EXP 6480464 deguelin results in increased cleavage of PARP1 protein CTD PMID:17035597 and PMID:22986522 PARP1 Human deguelin multiple interactions EXP 6480464 [NPM1 protein mutant form results in increased susceptibility to deguelin] which results in increased cleavage of PARP1 protein and deguelin inhibits the reaction [TNF protein results in increased cleavage of PARP1 protein] CTD PMID:17015749 and PMID:25242579 PARP1 Human delphinidin decreases activity EXP 6480464 delphinidin results in decreased activity of PARP1 protein CTD PMID:17884996 PARP1 Human delphinidin increases cleavage EXP 6480464 delphinidin results in increased cleavage of PARP1 protein CTD PMID:29451351 PARP1 Human demethoxycurcumin increases cleavage EXP 6480464 demethoxycurcumin results in increased cleavage of PARP1 protein CTD PMID:34291863 PARP1 Human demethoxycurcumin multiple interactions EXP 6480464 Wortmannin promotes the reaction [demethoxycurcumin results in increased cleavage of PARP1 protein] CTD PMID:34291863 PARP1 Human demethoxyfumitremorgin C increases cleavage EXP 6480464 demethoxyfumitremorgin C results in increased cleavage of PARP1 protein CTD PMID:28359723 PARP1 Human deoxycholic acid multiple interactions EXP 6480464 Aspirin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein] and cobaltiprotoporphyrin inhibits the reaction [Deoxycholic Acid results in increased cleavage of PARP1 protein] CTD PMID:17644113 and PMID:21362092 PARP1 Human deoxycholic acid increases cleavage EXP 6480464 Deoxycholic Acid results in increased cleavage of PARP1 protein CTD PMID:17644113 and PMID:21362092 PARP1 Human deoxynivalenol increases cleavage ISO Parp1 (Mus musculus) 6480464 deoxynivalenol results in increased cleavage of PARP1 protein CTD PMID:19410639 PARP1 Human deoxynivalenol increases expression EXP 6480464 deoxynivalenol results in increased expression of PARP1 mRNA CTD PMID:34677630 PARP1 Human deoxynivalenol multiple interactions ISO Parp1 (Mus musculus) 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone affects the reaction [deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein] and deoxynivalenol affects the expression of and results in increased cleavage of PARP1 protein CTD PMID:35925383 PARP1 Human deoxynivalenol multiple interactions EXP 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [deoxynivalenol results in decreased expression of and results in increased cleavage of PARP1 protein] more ... CTD PMID:35925383 PARP1 Human desferrioxamine B increases cleavage EXP 6480464 Deferoxamine results in increased cleavage of PARP1 protein CTD PMID:21882223 PARP1 Human desferrioxamine B multiple interactions EXP 6480464 Indomethacin promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein] and Sulindac promotes the reaction [Deferoxamine results in increased cleavage of PARP1 protein] CTD PMID:21882223 PARP1 Human desloratadine increases cleavage EXP 6480464 desloratadine results in increased cleavage of PARP1 protein CTD PMID:36617552 PARP1 Human desloratadine multiple interactions EXP 6480464 [desloratadine results in increased susceptibility to Sorafenib] which results in increased cleavage of PARP1 protein and [Sorafenib results in increased susceptibility to desloratadine] which results in increased cleavage of PARP1 protein CTD PMID:36617552 PARP1 Human Destruxin B increases cleavage EXP 6480464 destruxin B results in increased cleavage of PARP1 protein CTD PMID:22465936 PARP1 Human dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein modified form more ... CTD PMID:16144937 more ... PARP1 Human dexamethasone increases cleavage EXP 6480464 Dexamethasone results in increased cleavage of PARP1 protein CTD PMID:25447644 PARP1 Human dexamethasone multiple interactions ISO Parp1 (Mus musculus) 6480464 2 more ... CTD PMID:16644695 more ... PARP1 Human dexamethasone increases cleavage ISO Parp1 (Mus musculus) 6480464 Dexamethasone results in increased cleavage of PARP1 protein CTD PMID:16644695 PARP1 Human dexamethasone phosphate increases cleavage EXP 6480464 dexamethasone 21-phosphate results in increased cleavage of PARP1 protein CTD PMID:25447644 PARP1 Human dextran sulfate increases cleavage ISO Parp1 (Mus musculus) 6480464 Dextran Sulfate results in increased cleavage of PARP1 protein CTD PMID:21989142 PARP1 Human dextran sulfate multiple interactions ISO Parp1 (Mus musculus) 6480464 [Camptothecin co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased cleavage of PARP1 protein more ... CTD PMID:21989142 and PMID:25449198 PARP1 Human Diacetoxyscirpenol decreases expression ISO Parp1 (Mus musculus) 6480464 diacetoxyscirpenol results in decreased expression of PARP1 mRNA CTD PMID:31836554 PARP1 Human diallyl disulfide multiple interactions EXP 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] and diallyl disulfide promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:30677442 PARP1 Human diallyl trisulfide multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein] CTD PMID:22578287 PARP1 Human diallyl trisulfide increases cleavage EXP 6480464 diallyl trisulfide results in increased cleavage of PARP1 protein CTD PMID:20055834 more ... PARP1 Human diarsenic trioxide multiple interactions EXP 6480464 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] more ... CTD PMID:12883035 more ... PARP1 Human diarsenic trioxide increases activity ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased activity of PARP1 protein CTD PMID:24157283 PARP1 Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of PARP1 protein CTD PMID:19695276 and PMID:25419056 PARP1 Human diarsenic trioxide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein] and salvianolic acid A inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein] CTD PMID:24634002 and PMID:28391263 PARP1 Human diarsenic trioxide increases expression ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased expression of PARP1 protein modified form CTD PMID:29095437 PARP1 Human diarsenic trioxide multiple interactions ISO Parp1 (Mus musculus) 6480464 [Genistein co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein more ... CTD PMID:21078540 more ... PARP1 Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of PARP1 protein and Arsenic Trioxide results in increased expression of PARP1 protein modified form CTD PMID:25972196 and PMID:27430728 PARP1 Human diarsenic trioxide affects localization EXP 6480464 Arsenic Trioxide affects the localization of PARP1 protein modified form CTD PMID:15131059 PARP1 Human diarsenic trioxide increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:24634002 and PMID:32096187 PARP1 Human diarsenic trioxide increases activity EXP 6480464 Arsenic Trioxide results in increased activity of PARP1 protein CTD PMID:11304686 PARP1 Human diarsenic trioxide increases expression ISO Parp1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of PARP1 protein CTD PMID:28391263 PARP1 Human diarsenic trioxide increases degradation EXP 6480464 Arsenic Trioxide results in increased degradation of PARP1 protein CTD PMID:16166054 PARP1 Human diarsenic trioxide increases cleavage EXP 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:10382944 more ... PARP1 Human diarsenic trioxide increases cleavage ISO Parp1 (Mus musculus) 6480464 Arsenic Trioxide results in increased cleavage of PARP1 protein CTD PMID:15761769 more ... PARP1 Human dibenziodolium multiple interactions ISO Parp1 (Mus musculus) 6480464 diphenyleneiodonium inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein] CTD PMID:14687664 PARP1 Human dibenziodolium multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 diphenyleneiodonium inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein] CTD PMID:25947082 PARP1 Human Dibutyl phosphate affects expression EXP 6480464 di-n-butylphosphoric acid affects the expression of PARP1 mRNA CTD PMID:37042841 PARP1 Human dibutyl phthalate increases expression ISO Parp1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of PARP1 mRNA CTD PMID:21266533 PARP1 Human dibutyl phthalate decreases expression ISO Parp1 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of PARP1 mRNA CTD PMID:21266533 PARP1 Human dichloroacetic acid multiple interactions EXP 6480464 Dichloroacetic Acid results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:25630799 PARP1 Human dichlorvos increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Dichlorvos results in increased cleavage of PARP1 protein CTD PMID:24231740 PARP1 Human dichlorvos multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 N-(oxo-5 more ... CTD PMID:24231740 PARP1 Human dichlorvos increases activity ISO Parp1 (Rattus norvegicus) 6480464 Dichlorvos results in increased activity of PARP1 protein CTD PMID:24231740 PARP1 Human diclofenac affects expression EXP 6480464 Diclofenac affects the expression of PARP1 mRNA CTD PMID:24752500 PARP1 Human Dictamnine multiple interactions EXP 6480464 dictamnine results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:34861243 PARP1 Human Didecyldimethylammonium decreases expression EXP 6480464 didecyldimethylammonium results in decreased expression of PARP1 protein CTD PMID:32763356 PARP1 Human dieldrin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Dieldrin results in increased cleavage of PARP1 protein CTD PMID:15183012 PARP1 Human dieldrin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 benzoylcarbonyl-aspartyl-glutamyl-valyl-aspartyl-fluoromethyl ketone inhibits the reaction [Dieldrin results in increased cleavage of PARP1 protein] CTD PMID:15183012 PARP1 Human diepoxybutane increases cleavage EXP 6480464 diepoxybutane results in increased cleavage of PARP1 protein CTD PMID:14998682 PARP1 Human diethyl fumarate increases cleavage EXP 6480464 diethyl fumarate results in increased cleavage of PARP1 protein CTD PMID:21105742 PARP1 Human diethyl maleate increases cleavage EXP 6480464 diethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 PARP1 Human diethyl phthalate multiple interactions ISO Parp1 (Mus musculus) 6480464 diethyl phthalate results in increased expression of and results in increased cleavage of PARP1 protein CTD PMID:37942807 PARP1 Human dihydrogen multiple interactions EXP 6480464 Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] CTD PMID:26271894 PARP1 Human dihydroxyacetone increases cleavage EXP 6480464 Dihydroxyacetone results in increased cleavage of PARP1 protein CTD PMID:29193605 and PMID:38867704 PARP1 Human dimethyl maleate increases cleavage EXP 6480464 dimethyl maleate results in increased cleavage of PARP1 protein CTD PMID:21105742 PARP1 Human dimethyl sulfoxide increases cleavage ISO Parp1 (Mus musculus) 6480464 Dimethyl Sulfoxide results in increased cleavage of PARP1 protein CTD PMID:22535522 PARP1 Human dimethylarsinous acid decreases activity EXP 6480464 dimethylarsinous acid results in decreased activity of PARP1 protein CTD PMID:17011244 PARP1 Human dimethylarsinous acid multiple interactions EXP 6480464 [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein more ... CTD PMID:17011244 and PMID:29774349 PARP1 Human dinaciclib multiple interactions EXP 6480464 [dinaciclib results in increased susceptibility to Doxorubicin] which results in increased cleavage of PARP1 protein and dinaciclib promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein] CTD PMID:27378523 PARP1 Human dinaciclib increases cleavage EXP 6480464 dinaciclib results in increased cleavage of PARP1 protein CTD PMID:20663931 and PMID:27378523 PARP1 Human dioscin multiple interactions ISO Parp1 (Mus musculus) 6480464 dioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein] CTD PMID:24146112 PARP1 Human dioscin decreases expression EXP 6480464 dioscin results in decreased expression of PARP1 mRNA and dioscin results in decreased expression of PARP1 protein CTD PMID:33359023 PARP1 Human dioscin increases expression EXP 6480464 dioscin results in increased expression of PARP1 mRNA CTD PMID:29990575 PARP1 Human dioscin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 dioscin inhibits the reaction [Ethanol results in increased expression of PARP1 protein] CTD PMID:24146112 PARP1 Human diosmetin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of PARP1 protein modified form] more ... CTD PMID:35191607 PARP1 Human diosmin multiple interactions ISO Parp1 (Mus musculus) 6480464 Diosmin inhibits the reaction [Benzo(a)pyrene results in increased cleavage of PARP1 protein] CTD PMID:32061149 PARP1 Human dioxygen increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased cleavage of PARP1 protein CTD PMID:11042672 PARP1 Human dioxygen increases activity EXP 6480464 Oxygen deficiency results in increased activity of PARP1 protein CTD PMID:27288104 PARP1 Human dioxygen multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 gene mutant form inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of CXCL1 protein] CTD PMID:15696051 PARP1 Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of PARP1 protein modified form CTD PMID:26540049 PARP1 Human dioxygen increases cleavage EXP 6480464 Oxygen deficiency results in increased cleavage of PARP1 protein and Oxygen results in increased cleavage of PARP1 protein CTD PMID:20530905 and PMID:25831079 PARP1 Human dioxygen multiple interactions EXP 6480464 [betulin co-treated with Oxygen] results in increased cleavage of PARP1 protein more ... CTD PMID:20530905 more ... PARP1 Human dioxygen multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [N-(oxo-5 more ... CTD PMID:11042672 more ... PARP1 Human diprotium multiple interactions EXP 6480464 Hydrogen inhibits the reaction [APP protein results in increased cleavage of PARP1 protein] CTD PMID:26271894 PARP1 Human diquat increases cleavage EXP 6480464 Diquat results in increased cleavage of PARP1 protein CTD PMID:25693864 PARP1 Human disodium selenite increases cleavage EXP 6480464 Sodium Selenite results in increased cleavage of PARP1 protein CTD PMID:15845651 and PMID:28161410 PARP1 Human disodium selenite decreases activity ISO Parp1 (Rattus norvegicus) 6480464 Sodium Selenite results in decreased activity of PARP1 protein CTD PMID:18209489 PARP1 Human disodium selenite increases expression EXP 6480464 Sodium Selenite results in increased expression of PARP1 mRNA CTD PMID:18175754 PARP1 Human disulfiram multiple interactions EXP 6480464 [Copper co-treated with Disulfiram] results in increased cleavage of PARP1 protein more ... CTD PMID:17079463 more ... PARP1 Human disulfiram multiple interactions ISO Parp1 (Mus musculus) 6480464 [Disulfiram binds to Copper] which results in increased cleavage of PARP1 protein CTD PMID:24690739 PARP1 Human disulfiram increases cleavage EXP 6480464 Disulfiram results in increased cleavage of PARP1 protein CTD PMID:17079463 more ... PARP1 Human divinyl sulfone increases cleavage EXP 6480464 divinyl sulfone analog results in increased cleavage of PARP1 protein CTD PMID:24875536 PARP1 Human divinyl sulfone multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein] and Acetylcysteine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein] CTD PMID:24875536 PARP1 Human dizocilpine maleate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Dizocilpine Maleate inhibits the reaction [ammonium acetate results in increased expression of PARP1 protein] CTD PMID:15147502 PARP1 Human dopamine multiple interactions EXP 6480464 Dopamine promotes the reaction [Zinc deficiency results in increased cleavage of PARP1 protein] more ... CTD PMID:15198987 more ... PARP1 Human dopamine multiple interactions ISO Parp1 (Mus musculus) 6480464 [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:10318960 PARP1 Human dopamine increases cleavage EXP 6480464 Dopamine results in increased cleavage of PARP1 protein CTD PMID:15198987 more ... PARP1 Human dorsomorphin increases cleavage EXP 6480464 dorsomorphin results in increased cleavage of PARP1 protein CTD PMID:23274516 and PMID:31900833 PARP1 Human dorsomorphin multiple interactions EXP 6480464 dorsomorphin inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein] more ... CTD PMID:23274516 more ... PARP1 Human doxorubicin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Doxorubicin results in increased cleavage of PARP1 protein CTD PMID:16687611 more ... PARP1 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PARP1 mRNA CTD PMID:36634904 PARP1 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of PARP1 mRNA and Doxorubicin results in increased expression of PARP1 protein modified form CTD PMID:29803840 more ... PARP1 Human doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of PARP1 mRNA CTD PMID:27780733 PARP1 Human doxorubicin increases cleavage ISO Parp1 (Mus musculus) 6480464 Doxorubicin results in increased cleavage of PARP1 protein CTD PMID:10704466 more ... PARP1 Human doxorubicin increases expression ISO Parp1 (Mus musculus) 6480464 Doxorubicin results in increased expression of PARP1 protein CTD PMID:20144634 and PMID:31174020 PARP1 Human doxorubicin increases expression ISO Parp1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of PARP1 protein and Doxorubicin results in increased expression of PARP1 protein modified form CTD PMID:12967636 more ... PARP1 Human doxorubicin decreases activity ISO Parp1 (Mus musculus) 6480464 Doxorubicin results in decreased activity of PARP1 protein CTD PMID:20656019 PARP1 Human doxorubicin increases uptake ISO Parp1 (Mus musculus) 6480464 PARP1 protein results in increased uptake of Doxorubicin CTD PMID:15861398 PARP1 Human doxorubicin affects response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 protein affects the susceptibility to Doxorubicin CTD PMID:11861791 PARP1 Human doxorubicin increases activity ISO Parp1 (Mus musculus) 6480464 Doxorubicin results in increased activity of PARP1 protein CTD PMID:19286953 PARP1 Human doxorubicin multiple interactions ISO Parp1 (Mus musculus) 6480464 5 more ... CTD PMID:15861398 more ... PARP1 Human doxorubicin increases degradation EXP 6480464 Doxorubicin results in increased degradation of PARP1 protein CTD PMID:17418594 PARP1 Human doxorubicin increases activity EXP 6480464 Doxorubicin results in increased activity of PARP1 protein CTD PMID:15456408 PARP1 Human doxorubicin increases cleavage EXP 6480464 Doxorubicin analog results in increased cleavage of PARP1 protein and Doxorubicin results in increased cleavage of PARP1 protein CTD PMID:10766178 more ... PARP1 Human doxorubicin affects cleavage EXP 6480464 Doxorubicin affects the cleavage of PARP1 protein CTD PMID:15870702 PARP1 Human doxorubicin multiple interactions EXP 6480464 2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3 more ... CTD PMID:15456408 more ... PARP1 Human doxorubicin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] more ... CTD PMID:12967636 more ... PARP1 Human Echimidine multiple interactions EXP 6480464 echimidine results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:29458164 PARP1 Human edaravone increases cleavage EXP 6480464 Edaravone analog results in increased cleavage of PARP1 protein CTD PMID:25684395 PARP1 Human elemental selenium multiple interactions EXP 6480464 [Doxorubicin co-treated with Selenium] results in increased degradation of PARP1 protein more ... CTD PMID:17339365 PARP1 Human ellagic acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Ellagic Acid inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:25247703 PARP1 Human ellipticine increases cleavage EXP 6480464 ellipticine results in increased cleavage of PARP1 protein CTD PMID:21843585 PARP1 Human embelin increases cleavage EXP 6480464 embelin results in increased cleavage of PARP1 protein CTD PMID:24694877 and PMID:28722333 PARP1 Human embelin multiple interactions EXP 6480464 3-methyladenine promotes the reaction [embelin results in increased cleavage of PARP1 protein] CTD PMID:28722333 PARP1 Human emetine increases cleavage EXP 6480464 Emetine results in increased cleavage of PARP1 protein CTD PMID:21256112 PARP1 Human emodin increases activity EXP 6480464 Emodin results in increased activity of PARP1 protein CTD PMID:23848338 PARP1 Human emodin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Emodin results in increased cleavage of PARP1 protein] more ... CTD PMID:27032576 PARP1 Human emodin increases cleavage EXP 6480464 Emodin results in increased cleavage of PARP1 protein CTD PMID:27032576 more ... PARP1 Human Enterolactone multiple interactions EXP 6480464 [Coumestrol co-treated with 2 and 3-bis(3'-hydroxybenzyl)butyrolactone] results in increased expression of PARP1 mRNA CTD PMID:19167446 PARP1 Human enzalutamide decreases cleavage EXP 6480464 enzalutamide results in decreased cleavage of PARP1 protein CTD PMID:32184358 PARP1 Human enzalutamide multiple interactions EXP 6480464 [enzalutamide co-treated with GSK-2816126] results in increased cleavage of PARP1 protein more ... CTD PMID:30940724 more ... PARP1 Human enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PARP1 protein CTD PMID:23301498 PARP1 Human epalrestat multiple interactions ISO Parp1 (Mus musculus) 6480464 epalrestat analog inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] and epalrestat inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] CTD PMID:37257577 PARP1 Human epothilone A multiple interactions EXP 6480464 [epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA more ... CTD PMID:29117515 PARP1 Human epothilone A increases expression EXP 6480464 epothilone A results in increased expression of PARP1 mRNA CTD PMID:29117515 PARP1 Human epoxomicin increases cleavage EXP 6480464 epoxomicin results in increased cleavage of PARP1 protein CTD PMID:20153345 PARP1 Human epoxomicin multiple interactions EXP 6480464 quinoline-val-asp(OMe)-CH2-OPH inhibits the reaction [epoxomicin results in increased cleavage of PARP1 protein] CTD PMID:20153345 PARP1 Human erastin increases cleavage EXP 6480464 erastin results in increased cleavage of PARP1 protein CTD PMID:38641223 PARP1 Human erastin multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide promotes the reaction [erastin results in increased cleavage of PARP1 protein] CTD PMID:38641223 PARP1 Human erdosteine multiple interactions ISO Parp1 (Mus musculus) 6480464 erdosteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein] CTD PMID:26193055 PARP1 Human erdosteine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 erdosteine affects the reaction [Isoproterenol results in increased expression of PARP1 protein] CTD PMID:33210414 PARP1 Human erlotinib hydrochloride increases expression EXP 6480464 Erlotinib Hydrochloride results in increased expression of PARP1 protein modified form CTD PMID:25895606 PARP1 Human erlotinib hydrochloride increases cleavage EXP 6480464 Erlotinib Hydrochloride results in increased cleavage of PARP1 protein CTD PMID:23125191 and PMID:30171258 PARP1 Human erlotinib hydrochloride multiple interactions EXP 6480464 [TWIST1 protein results in decreased susceptibility to Erlotinib Hydrochloride] which results in decreased cleavage of PARP1 protein more ... CTD PMID:25895606 and PMID:30171258 PARP1 Human esculetin increases cleavage EXP 6480464 esculetin results in increased cleavage of PARP1 protein CTD PMID:26388407 and PMID:31313495 PARP1 Human etacrynic acid multiple interactions EXP 6480464 [arsenic trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein more ... CTD PMID:23082001 PARP1 Human ethanol multiple interactions EXP 6480464 Ethanol results in increased expression of and results in increased cleavage of PARP1 protein more ... CTD PMID:21410490 more ... PARP1 Human ethanol affects splicing ISO Parp1 (Mus musculus) 6480464 Ethanol affects the splicing of PARP1 mRNA CTD PMID:30319688 PARP1 Human ethanol increases activity ISO Parp1 (Rattus norvegicus) 6480464 Ethanol results in increased activity of PARP1 protein CTD PMID:30368987 PARP1 Human ethanol increases activity ISO Parp1 (Mus musculus) 6480464 Ethanol results in increased activity of PARP1 protein CTD PMID:27984176 PARP1 Human ethanol increases cleavage EXP 6480464 Ethanol results in increased cleavage of PARP1 protein CTD PMID:21410490 more ... PARP1 Human ethanol increases expression ISO Parp1 (Mus musculus) 6480464 Ethanol results in increased expression of PARP1 protein CTD PMID:24146112 more ... PARP1 Human ethanol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [2 more ... CTD PMID:24146112 more ... PARP1 Human ethanol multiple interactions ISO Parp1 (Mus musculus) 6480464 5-aminoisoquinolinone inhibits the reaction [Ethanol results in increased activity of PARP1 protein] more ... CTD PMID:24146112 more ... PARP1 Human ethanol increases cleavage ISO Parp1 (Mus musculus) 6480464 Ethanol results in increased cleavage of PARP1 protein CTD PMID:22535522 and PMID:34116071 PARP1 Human ethanol increases expression ISO Parp1 (Rattus norvegicus) 6480464 Ethanol results in increased expression of PARP1 mRNA and Ethanol results in increased expression of PARP1 protein CTD PMID:15353170 more ... PARP1 Human ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 [1 more ... CTD PMID:29111403 PARP1 Human ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 PARP1 Human ethylene glycol bis(2-aminoethyl)tetraacetic acid multiple interactions EXP 6480464 Egtazic Acid inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein] CTD PMID:21544200 PARP1 Human etoposide increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Etoposide results in increased cleavage of PARP1 protein CTD PMID:17516866 PARP1 Human etoposide increases cleavage EXP 6480464 Etoposide results in increased cleavage of PARP1 protein CTD PMID:12690110 more ... PARP1 Human etoposide multiple interactions EXP 6480464 3' more ... CTD PMID:16014620 more ... PARP1 Human etoposide increases degradation EXP 6480464 Etoposide results in increased degradation of PARP1 protein CTD PMID:8840993 PARP1 Human etoposide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Niacin deficiency affects the reaction [Etoposide results in increased cleavage of PARP1 protein] CTD PMID:17516866 PARP1 Human eugenol multiple interactions ISO Parp1 (Mus musculus) 6480464 Eugenol affects the reaction [Methylnitronitrosoguanidine affects the cleavage of PARP1 protein] CTD PMID:20434464 PARP1 Human EUK-134 multiple interactions EXP 6480464 EUK-134 inhibits the reaction [evodiamine results in increased cleavage of PARP1 protein] CTD PMID:34808100 PARP1 Human everolimus multiple interactions EXP 6480464 [navitoclax co-treated with Everolimus] results in increased cleavage of PARP1 protein CTD PMID:28947240 PARP1 Human Evodiamine multiple interactions EXP 6480464 EUK-134 inhibits the reaction [evodiamine results in increased cleavage of PARP1 protein] more ... CTD PMID:15710601 and PMID:34808100 PARP1 Human Evodiamine increases cleavage EXP 6480464 evodiamine results in increased cleavage of PARP1 protein CTD PMID:34808100 PARP1 Human excitatory amino acid agonist increases activity ISO Parp1 (Rattus norvegicus) 6480464 Excitatory Amino Acid Agonists results in increased activity of PARP1 protein CTD PMID:19288225 PARP1 Human excitatory amino acid agonist decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Excitatory Amino Acid Agonists results in decreased expression of PARP1 protein CTD PMID:19288225 PARP1 Human excitatory amino acid agonist multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Niacinamide inhibits the reaction [Excitatory Amino Acid Agonists results in decreased expression of PARP1 protein] more ... CTD PMID:19288225 and PMID:24675465 PARP1 Human excitatory amino acid agonist increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Excitatory Amino Acid Agonists results in increased cleavage of PARP1 protein CTD PMID:24675465 PARP1 Human fangchinoline increases cleavage EXP 6480464 fangchinoline results in increased cleavage of PARP1 protein CTD PMID:28754437 PARP1 Human fenvalerate increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 fenvalerate results in increased cleavage of PARP1 protein CTD PMID:30307764 PARP1 Human fenvalerate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 CAT protein inhibits the reaction [fenvalerate results in increased cleavage of PARP1 protein] CTD PMID:30307764 PARP1 Human ferric ammonium citrate multiple interactions EXP 6480464 [ferric ammonium citrate results in increased abundance of Iron] which results in decreased expression of PARP1 protein more ... CTD PMID:34826546 PARP1 Human ferric oxide multiple interactions ISO Parp1 (Mus musculus) 6480464 ferric oxide results in decreased expression of and results in increased cleavage of PARP1 protein CTD PMID:28993115 PARP1 Human ferric oxide increases cleavage ISO Parp1 (Mus musculus) 6480464 ferric oxide results in increased cleavage of PARP1 protein CTD PMID:26991130 PARP1 Human ferric oxide increases cleavage EXP 6480464 ferric oxide analog results in increased cleavage of PARP1 protein CTD PMID:27270449 PARP1 Human ferrosoferric oxide multiple interactions EXP 6480464 [Ferrosoferric Oxide binds to titanium dioxide] which results in decreased expression of PARP1 protein CTD PMID:30098274 PARP1 Human fingolimod hydrochloride increases cleavage EXP 6480464 Fingolimod Hydrochloride results in increased cleavage of PARP1 protein CTD PMID:25939952 PARP1 Human fingolimod hydrochloride multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein] more ... CTD PMID:25939952 PARP1 Human fisetin decreases activity EXP 6480464 fisetin results in decreased activity of PARP1 protein CTD PMID:17884996 PARP1 Human flavanone increases cleavage EXP 6480464 flavanone results in increased cleavage of PARP1 protein CTD PMID:22056764 PARP1 Human flavanones multiple interactions EXP 6480464 3-methyladenine promotes the reaction [Flavanones results in increased cleavage of PARP1 protein] more ... CTD PMID:21616090 PARP1 Human flavanones increases cleavage EXP 6480464 Flavanones results in increased cleavage of PARP1 protein CTD PMID:21616090 PARP1 Human flavokawain B multiple interactions EXP 6480464 [ATG5 protein affects the susceptibility to flavokawain B] which affects the cleavage of PARP1 protein more ... CTD PMID:30025493 PARP1 Human flavone increases cleavage EXP 6480464 flavone results in increased cleavage of PARP1 protein CTD PMID:15289867 PARP1 Human flavone decreases activity EXP 6480464 flavone results in decreased activity of PARP1 protein CTD PMID:17643414 PARP1 Human flavonoids increases cleavage EXP 6480464 Flavonoids results in increased cleavage of PARP1 protein CTD PMID:23063593 PARP1 Human flavonoids increases expression ISO Parp1 (Rattus norvegicus) 6480464 Flavonoids results in increased expression of PARP1 mRNA CTD PMID:18035473 PARP1 Human flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of PARP1 mRNA CTD PMID:15465739 PARP1 Human floxuridine decreases response to substance EXP 6480464 PARP1 protein results in decreased susceptibility to Floxuridine CTD PMID:21613406 PARP1 Human fludioxonil increases expression EXP 6480464 fludioxonil results in increased expression of PARP1 protein CTD PMID:23052036 PARP1 Human fluoranthene increases cleavage EXP 6480464 fluoranthene results in increased cleavage of PARP1 protein CTD PMID:21132278 PARP1 Human flutamide increases expression ISO Parp1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of PARP1 mRNA CTD PMID:24136188 PARP1 Human folic acid increases cleavage EXP 6480464 Folic Acid results in increased cleavage of PARP1 protein CTD PMID:16728583 PARP1 Human folic acid decreases expression EXP 6480464 Folic Acid results in decreased expression of PARP1 mRNA CTD PMID:36354958 PARP1 Human folic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of PARP1 mRNA] CTD PMID:22206623 PARP1 Human folic acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Folic Acid inhibits the reaction [Methotrexate results in increased cleavage of PARP1 protein] and Folic Acid inhibits the reaction [Nicotine results in decreased expression of PARP1 protein] CTD PMID:29972271 and PMID:30502384 PARP1 Human formaldehyde decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Formaldehyde results in decreased expression of PARP1 mRNA CTD PMID:17285311 PARP1 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of PARP1 protein modified form CTD PMID:24140967 PARP1 Human FR900359 increases phosphorylation EXP 6480464 FR900359 results in increased phosphorylation of PARP1 protein CTD PMID:37730182 PARP1 Human fraxetin increases cleavage EXP 6480464 fraxetin results in increased cleavage of PARP1 protein CTD PMID:37867445 PARP1 Human frenolicin B increases cleavage EXP 6480464 frenolicin B results in increased cleavage of PARP1 protein CTD PMID:30661989 PARP1 Human frenolicin B multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [frenolicin B results in increased cleavage of PARP1 protein] CTD PMID:30661989 PARP1 Human friedelin multiple interactions ISO Parp1 (Mus musculus) 6480464 friedelin inhibits the reaction [Ethanol results in increased expression of PARP1 protein] CTD PMID:37939858 PARP1 Human fructose increases expression ISO Parp1 (Mus musculus) 6480464 Fructose results in increased expression of PARP1 protein CTD PMID:28257781 PARP1 Human fucoxanthin multiple interactions EXP 6480464 BCL2L1 protein inhibits the reaction [fucoxanthin results in increased cleavage of PARP1 protein] more ... CTD PMID:38444163 PARP1 Human fucoxanthin increases cleavage EXP 6480464 fucoxanthin results in increased cleavage of PARP1 protein CTD PMID:38444163 PARP1 Human fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Estradiol results in increased cleavage of PARP1 protein] and fulvestrant inhibits the reaction [Quercetin results in increased cleavage of PARP1 protein] CTD PMID:21732360 PARP1 Human fumonisin B1 multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 fumonisin B1 inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein] CTD PMID:24448832 PARP1 Human fumonisin B1 decreases cleavage EXP 6480464 fumonisin B1 results in decreased cleavage of PARP1 protein CTD PMID:25800559 PARP1 Human furazolidone multiple interactions EXP 6480464 CDKN1A protein inhibits the reaction [Furazolidone results in increased phosphorylation of PARP1 protein] CTD PMID:26687534 PARP1 Human furazolidone increases cleavage EXP 6480464 Furazolidone results in increased cleavage of PARP1 protein CTD PMID:26687534 PARP1 Human galangin increases cleavage EXP 6480464 galangin results in increased cleavage of PARP1 protein CTD PMID:18455702 PARP1 Human gallic acid increases cleavage EXP 6480464 Gallic Acid results in increased cleavage of PARP1 protein CTD PMID:27060209 PARP1 Human gallic acid multiple interactions EXP 6480464 1 more ... CTD PMID:27060209 PARP1 Human gamma-linolenic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 gamma-Linolenic Acid results in increased cleavage of PARP1 protein CTD PMID:10403056 PARP1 Human Garcinol increases cleavage EXP 6480464 garcinol results in increased cleavage of PARP1 protein CTD PMID:16052481 PARP1 Human gardenin B increases cleavage EXP 6480464 gardenin B results in increased cleavage of PARP1 protein CTD PMID:27423764 PARP1 Human gefitinib multiple interactions EXP 6480464 Betulinic Acid promotes the reaction [Gefitinib results in increased cleavage of PARP1 protein] and Gefitinib affects the reaction [Oxaliplatin results in increased cleavage of PARP1 protein] CTD PMID:16243822 and PMID:30136359 PARP1 Human gefitinib increases expression ISO Parp1 (Mus musculus) 6480464 Gefitinib results in increased expression of PARP1 protein modified form CTD PMID:33248157 PARP1 Human gefitinib multiple interactions ISO Parp1 (Mus musculus) 6480464 [Gefitinib results in increased secretion of CCL2 protein] inhibits the reaction [Gefitinib results in increased expression of PARP1 protein modified form] CTD PMID:33248157 PARP1 Human gefitinib increases cleavage EXP 6480464 gefitinib results in increased cleavage of PARP1 protein CTD PMID:23523951 PARP1 Human geldanamycin multiple interactions EXP 6480464 geldanamycin inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] and Tretinoin inhibits the reaction [geldanamycin results in increased degradation of PARP1 protein] CTD PMID:16311509 and PMID:17293044 PARP1 Human geldanamycin increases degradation EXP 6480464 geldanamycin results in increased degradation of PARP1 protein CTD PMID:17293044 PARP1 Human gemcitabine increases cleavage EXP 6480464 Gemcitabine results in increased cleavage of PARP1 protein CTD PMID:17146438 and PMID:26894857 PARP1 Human gemcitabine multiple interactions EXP 6480464 [alvocidib co-treated with Gemcitabine] results in increased cleavage of PARP1 protein more ... CTD PMID:15770523 more ... PARP1 Human genistein multiple interactions EXP 6480464 [Fluorouracil co-treated with Genistein] results in increased cleavage of PARP1 protein and [Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein CTD PMID:15896711 and PMID:21078540 PARP1 Human genistein increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Genistein results in increased cleavage of PARP1 protein CTD PMID:24884420 PARP1 Human genistein multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Genistein inhibits the reaction [bisphenol A results in decreased cleavage of PARP1 protein] CTD PMID:24884420 PARP1 Human genistein increases cleavage ISO Parp1 (Mus musculus) 6480464 Genistein results in increased cleavage of PARP1 protein CTD PMID:21078540 and PMID:25756279 PARP1 Human genistein increases cleavage EXP 6480464 Genistein results in increased cleavage of PARP1 protein CTD PMID:12791511 and PMID:21078540 PARP1 Human genistein multiple interactions ISO Parp1 (Mus musculus) 6480464 [Genistein co-treated with arsenic trioxide] results in increased cleavage of PARP1 protein CTD PMID:21078540 PARP1 Human gentamycin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of PARP1 protein] CTD PMID:11470263 PARP1 Human gentamycin increases activity ISO Parp1 (Rattus norvegicus) 6480464 Gentamicins results in increased activity of PARP1 protein CTD PMID:11470263 PARP1 Human gentamycin increases expression ISO Parp1 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of PARP1 mRNA CTD PMID:22061828 PARP1 Human Gentiopicrin multiple interactions ISO Parp1 (Mus musculus) 6480464 gentiopicroside inhibits the reaction [[[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein] CTD PMID:20558151 PARP1 Human Geraniin increases cleavage EXP 6480464 Geraniin results in increased cleavage of PARP1 protein CTD PMID:27097871 PARP1 Human gingerol multiple interactions EXP 6480464 [TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein and Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein] CTD PMID:25034532 PARP1 Human Ginkgoic acid increases cleavage EXP 127284886 Ginkgoic acid increases cleavage of PARP1 protein in stomach RGD PARP1 Human ginsenoside Re multiple interactions EXP 6480464 ginsenoside Re inhibits the reaction [Methamphetamine results in increased cleavage of PARP1 protein] CTD PMID:25523949 PARP1 Human glabridin increases cleavage EXP 6480464 glabridin results in increased cleavage of PARP1 protein CTD PMID:29663662 PARP1 Human glucose multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [INS1 protein co-treated with Glucose] results in increased activity of PARP1 protein more ... CTD PMID:18004065 more ... PARP1 Human glucose increases activity EXP 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:21031461 and PMID:27288104 PARP1 Human glucose increases acetylation EXP 6480464 Glucose results in increased acetylation of PARP1 protein CTD PMID:28478229 PARP1 Human glucose affects localization EXP 6480464 Glucose affects the localization of PARP1 protein CTD PMID:28478229 PARP1 Human glucose multiple interactions ISO Parp1 (Mus musculus) 6480464 Glucose deficiency inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form] and PARP1 protein affects the reaction [Glucose results in increased ADP-ribosylation of GAPDH protein] CTD PMID:14523042 and PMID:29095437 PARP1 Human glucose increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased cleavage of PARP1 protein CTD PMID:22524206 PARP1 Human glucose increases expression EXP 6480464 Glucose results in increased expression of PARP1 mRNA and Glucose results in increased expression of PARP1 protein modified form CTD PMID:22228707 more ... PARP1 Human glucose decreases expression ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in decreased expression of PARP1 mRNA and Glucose results in decreased expression of PARP1 protein CTD PMID:21818840 and PMID:37619648 PARP1 Human glucose increases activity ISO Parp1 (Rattus norvegicus) 6480464 Glucose results in increased activity of PARP1 protein CTD PMID:18004065 PARP1 Human glucose multiple interactions EXP 6480464 [Glucose co-treated with Oxygen deficiency] results in increased activity of PARP1 protein more ... CTD PMID:14523042 more ... PARP1 Human glutathione multiple interactions EXP 6480464 Glutathione deficiency promotes the reaction [antimony trioxide results in increased cleavage of PARP1 protein] more ... CTD PMID:14660655 more ... PARP1 Human Glutathione ethyl ester multiple interactions EXP 6480464 S-ethyl glutathione inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein] more ... CTD PMID:22733624 more ... PARP1 Human glutinol multiple interactions ISO Parp1 (Mus musculus) 6480464 glutinol inhibits the reaction [Ethanol results in increased expression of PARP1 protein] CTD PMID:37939858 PARP1 Human glycerol 2-phosphate multiple interactions ISO Parp1 (Mus musculus) 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA more ... CTD PMID:26492236 PARP1 Human glycerol 2-phosphate multiple interactions EXP 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein modified form more ... CTD PMID:22940495 PARP1 Human glycochenodeoxycholic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 Glycochenodeoxycholic Acid results in increased cleavage of PARP1 protein CTD PMID:25125499 PARP1 Human glyphosate decreases expression EXP 6480464 Glyphosate results in decreased expression of PARP1 mRNA CTD PMID:31295307 PARP1 Human glyphosate increases cleavage ISO Parp1 (Mus musculus) 6480464 Glyphosate results in increased cleavage of PARP1 protein CTD PMID:29908847 PARP1 Human glyphosate multiple interactions ISO Parp1 (Mus musculus) 6480464 XAF1 protein affects the reaction [Glyphosate results in increased cleavage of PARP1 protein] CTD PMID:29908847 PARP1 Human Goe 6976 multiple interactions EXP 6480464 Go 6976 inhibits the reaction [[cholix toxin and Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein] CTD PMID:28087840 PARP1 Human gold atom multiple interactions EXP 6480464 Organogold Compounds promotes the reaction [Gold binds to PARP1 protein] CTD PMID:21370912 PARP1 Human gold atom decreases expression EXP 6480464 Gold analog results in decreased expression of PARP1 mRNA CTD PMID:36057382 PARP1 Human gold(0) multiple interactions EXP 6480464 Organogold Compounds promotes the reaction [Gold binds to PARP1 protein] CTD PMID:21370912 PARP1 Human gold(0) decreases expression EXP 6480464 Gold analog results in decreased expression of PARP1 mRNA CTD PMID:36057382 PARP1 Human gossypetin decreases activity EXP 6480464 gossypetin results in decreased activity of PARP1 protein CTD PMID:17884996 PARP1 Human gossypetin multiple interactions EXP 6480464 gossypetin inhibits the reaction [malondialdehyde-low density lipoprotein and human results in increased cleavage of PARP1 protein] CTD PMID:25622137 PARP1 Human gossypin increases cleavage EXP 6480464 gossypin results in increased cleavage of PARP1 protein CTD PMID:30536456 PARP1 Human gossypol multiple interactions EXP 6480464 [Gossypol co-treated with Epirubicin] results in increased cleavage of PARP1 protein CTD PMID:35872041 PARP1 Human GSK2656157 multiple interactions EXP 6480464 GSK2656157 inhibits the reaction [glyceryl 2-arachidonate results in increased cleavage of PARP1 protein] CTD PMID:32357311 PARP1 Human GSK690693 multiple interactions EXP 6480464 GSK690693 promotes the reaction [1 and 4-naphthoquinone analog results in increased cleavage of PARP1 protein] CTD PMID:30871965 PARP1 Human GW 3965 multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 GW 3965 inhibits the reaction [Palmitates results in increased cleavage of PARP1 protein] CTD PMID:21209018 PARP1 Human GW 4064 decreases phosphorylation ISO Parp1 (Mus musculus) 6480464 GW 4064 results in decreased phosphorylation of PARP1 protein CTD PMID:23178280 PARP1 Human GW 501516 multiple interactions EXP 6480464 GW 501516 promotes the reaction [Indomethacin results in increased cleavage of PARP1 protein] CTD PMID:21400612 PARP1 Human harman increases cleavage EXP 6480464 harman results in increased cleavage of PARP1 protein CTD PMID:35985368 PARP1 Human harmine multiple interactions EXP 6480464 Harmine promotes the reaction [Erlotinib Hydrochloride results in increased cleavage of PARP1 protein] CTD PMID:30171258 PARP1 Human Heliotrine decreases expression EXP 6480464 heliotrine results in decreased expression of PARP1 protein CTD PMID:29458164 PARP1 Human hellebrigenin increases activity EXP 6480464 hellebrigenin results in increased activity of PARP1 protein CTD PMID:24954031 PARP1 Human heparin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Heparin promotes the reaction [Doxorubicin results in increased cleavage of PARP1 protein] CTD PMID:30377735 PARP1 Human herbimycin increases cleavage ISO Parp1 (Mus musculus) 6480464 herbimycin results in increased cleavage of PARP1 protein CTD PMID:11035063 PARP1 Human hesperidin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Hesperidin co-treated with Chlorpyrifos] results in increased expression of PARP1 mRNA more ... CTD PMID:30368987 and PMID:33908150 PARP1 Human hexadecanoic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 Palmitic Acid results in increased cleavage of PARP1 protein CTD PMID:30208301 PARP1 Human hexadecanoic acid increases expression ISO Parp1 (Mus musculus) 6480464 Palmitic Acid results in increased expression of PARP1 protein modified form CTD PMID:34678374 PARP1 Human hexadecanoic acid increases expression ISO Parp1 (Rattus norvegicus) 6480464 Palmitic Acid results in increased expression of PARP1 mRNA and Palmitic Acid results in increased expression of PARP1 protein CTD PMID:19513971 PARP1 Human hexadecanoic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 carnosol inhibits the reaction [Palmitic Acid results in increased expression of PARP1 protein modified form] more ... CTD PMID:30208301 and PMID:34678374 PARP1 Human homoeriodictyol multiple interactions EXP 6480464 homoeriodictyol inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein] CTD PMID:29902531 PARP1 Human homovanillic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 [PARP1 protein results in increased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:10318960 PARP1 Human Honokiol increases cleavage EXP 6480464 honokiol results in increased cleavage of PARP1 protein CTD PMID:15802533 PARP1 Human hydralazine multiple interactions EXP 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of PARP1 mRNA CTD PMID:17183730 PARP1 Human hydrogen peroxide increases activity EXP 6480464 Hydrogen Peroxide results in increased activity of PARP1 protein CTD PMID:11217149 more ... PARP1 Human hydrogen peroxide decreases expression ISO Parp1 (Mus musculus) 6480464 Hydrogen Peroxide results in decreased expression of PARP1 protein CTD PMID:26218895 PARP1 Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of PARP1 protein CTD PMID:17961220 PARP1 Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of PARP1 protein modified form CTD PMID:16709600 and PMID:23726866 PARP1 Human hydrogen peroxide increases ADP-ribosylation EXP 6480464 Hydrogen Peroxide results in increased ADP-ribosylation of PARP1 protein CTD PMID:27694308 PARP1 Human hydrogen peroxide increases response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 protein results in increased susceptibility to Hydrogen Peroxide CTD PMID:20878536 and PMID:26218895 PARP1 Human hydrogen peroxide increases cleavage ISO Parp1 (Mus musculus) 6480464 Hydrogen Peroxide results in increased cleavage of PARP1 protein CTD PMID:15876423 more ... PARP1 Human hydrogen peroxide increases expression ISO Parp1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of PARP1 protein modified form CTD PMID:22081883 PARP1 Human hydrogen peroxide increases activity ISO Parp1 (Mus musculus) 6480464 Hydrogen Peroxide results in increased activity of PARP1 protein CTD PMID:11593040 and PMID:24814482 PARP1 Human hydrogen peroxide increases degradation ISO Parp1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased degradation of PARP1 protein CTD PMID:16157298 PARP1 Human hydrogen peroxide decreases response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 gene mutant form results in decreased susceptibility to Hydrogen Peroxide CTD PMID:17438151 PARP1 Human hydrogen peroxide multiple interactions ISO Parp1 (Mus musculus) 6480464 [benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Hydrogen Peroxide more ... CTD PMID:11593040 more ... PARP1 Human hydrogen peroxide affects response to substance EXP 6480464 PARP1 protein affects the susceptibility to Hydrogen Peroxide CTD PMID:19111594 and PMID:27694308 PARP1 Human hydrogen peroxide increases cleavage EXP 6480464 Hydrogen Peroxide results in increased cleavage of PARP1 protein CTD PMID:19815691 more ... PARP1 Human hydrogen peroxide multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Hydrogen Peroxide results in increased activity of PARP1 protein] more ... CTD PMID:11217149 more ... PARP1 Human hydrogen peroxide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Rotenone results in increased abundance of Hydrogen Peroxide] which results in increased cleavage of PARP1 protein more ... CTD PMID:14505808 more ... PARP1 Human hydrogen peroxide increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased cleavage of PARP1 protein CTD PMID:14505808 more ... PARP1 Human hydroquinone increases cleavage EXP 6480464 hydroquinone results in increased cleavage of PARP1 protein CTD PMID:19064679 more ... PARP1 Human hydroquinone decreases expression EXP 6480464 hydroquinone results in decreased expression of PARP1 protein CTD PMID:26822515 PARP1 Human hydroquinone increases degradation EXP 6480464 hydroquinone results in increased degradation of PARP1 protein CTD PMID:35302183 PARP1 Human hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of PARP1 protein CTD PMID:28263894 more ... PARP1 Human hydroquinone affects response to substance EXP 6480464 PARP1 protein affects the susceptibility to hydroquinone CTD PMID:26335980 and PMID:28444915 PARP1 Human hydroquinone affects expression EXP 6480464 hydroquinone affects the expression of PARP1 protein CTD PMID:26047893 PARP1 Human hydroquinone increases response to substance EXP 6480464 PARP1 protein results in increased susceptibility to hydroquinone CTD PMID:26047893 PARP1 Human hydroquinone multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [hydroquinone results in increased expression of PARP1 protein] more ... CTD PMID:19064679 more ... PARP1 Human hydroxamic acid increases cleavage EXP 6480464 Hydroxamic Acids results in increased cleavage of PARP1 protein CTD PMID:27163855 PARP1 Human hydroxychloroquine multiple interactions EXP 6480464 Hydroxychloroquine inhibits the reaction [beta-ionone results in increased cleavage of PARP1 protein] CTD PMID:36843289 PARP1 Human icariside II multiple interactions EXP 6480464 Dinoprostone inhibits the reaction [baohuoside I results in increased cleavage of PARP1 protein] and PTGS2 mutant form promotes the reaction [baohuoside I results in increased cleavage of PARP1 protein] CTD PMID:19289254 PARP1 Human icariside II increases cleavage EXP 6480464 baohuoside I results in increased cleavage of PARP1 protein CTD PMID:19289254 and PMID:22687635 PARP1 Human idarubicin increases expression ISO Parp1 (Mus musculus) 6480464 Idarubicin results in increased expression of PARP1 mRNA and Idarubicin results in increased expression of PARP1 protein CTD PMID:28973540 PARP1 Human idarubicin multiple interactions ISO Parp1 (Mus musculus) 6480464 Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 mRNA] and Dexrazoxane inhibits the reaction [Idarubicin results in increased expression of PARP1 protein] CTD PMID:28973540 PARP1 Human idelalisib multiple interactions EXP 6480464 [palbociclib results in increased susceptibility to idelalisib] which results in increased cleavage of PARP1 protein CTD PMID:23676220 PARP1 Human Ilimaquinone multiple interactions EXP 6480464 [ilimaquinone results in increased susceptibility to TNFSF10 protein] which results in increased cleavage of PARP1 protein and ilimaquinone promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein] CTD PMID:24930757 PARP1 Human Ilimaquinone increases cleavage EXP 6480464 ilimaquinone results in increased cleavage of PARP1 protein CTD PMID:24930757 PARP1 Human imipramine increases cleavage EXP 6480464 Imipramine results in increased cleavage of PARP1 protein CTD PMID:10487422 PARP1 Human Indeno[1,2,3-cd]pyrene increases cleavage EXP 6480464 indeno(1 more ... CTD PMID:21132278 PARP1 Human indole-3-butyric acid increases cleavage EXP 6480464 indolebutyric acid analog results in increased cleavage of PARP1 protein CTD PMID:23499788 PARP1 Human indole-3-methanol multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [indole-3-carbinol results in increased cleavage of PARP1 protein] more ... CTD PMID:15811958 more ... PARP1 Human indole-3-methanol increases cleavage EXP 6480464 indole-3-carbinol results in increased cleavage of PARP1 protein CTD PMID:33118390 PARP1 Human indole-3-methanol increases cleavage ISO Parp1 (Mus musculus) 6480464 indole-3-carbinol results in increased cleavage of PARP1 protein CTD PMID:29775573 PARP1 Human indometacin multiple interactions EXP 6480464 (4-(((2-(3-fluoro-4-(trifluoromethyl)phenyl)-4-methyl-1 more ... CTD PMID:17873517 more ... PARP1 Human indometacin increases cleavage EXP 6480464 Indomethacin results in increased cleavage of PARP1 protein CTD PMID:11532860 more ... PARP1 Human iodoacetic acid increases expression EXP 6480464 Iodoacetic Acid results in increased expression of PARP1 protein modified form CTD PMID:25944804 PARP1 Human irinotecan multiple interactions EXP 6480464 rucaparib inhibits the reaction [Irinotecan results in increased expression of PARP1 protein] CTD PMID:30612311 PARP1 Human irinotecan increases expression EXP 6480464 Irinotecan results in increased expression of PARP1 protein CTD PMID:30612311 PARP1 Human iron atom multiple interactions EXP 6480464 [Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein more ... CTD PMID:30626086 more ... PARP1 Human iron(0) multiple interactions EXP 6480464 [Acetaminophen co-treated with [ferric nitrate results in increased abundance of Iron]] results in increased cleavage of PARP1 protein more ... CTD PMID:30626086 more ... PARP1 Human isoalantolactone increases cleavage EXP 6480464 isoalantolactone results in increased cleavage of PARP1 protein CTD PMID:29800641 PARP1 Human isoalantolactone increases expression EXP 6480464 isoalantolactone results in increased expression of PARP1 protein modified form CTD PMID:29800641 PARP1 Human isoalantolactone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form] more ... CTD PMID:29800641 PARP1 Human isobavachalcone increases cleavage EXP 6480464 isobavachalcone results in increased cleavage of PARP1 protein CTD PMID:30890322 PARP1 Human Isoliensinine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [isoliensinine results in increased cleavage of PARP1 protein] more ... CTD PMID:26219228 PARP1 Human Isoliensinine increases cleavage EXP 6480464 isoliensinine results in increased cleavage of PARP1 protein CTD PMID:26219228 PARP1 Human isoliquiritigenin multiple interactions EXP 6480464 benzyloxycarbonyl-leucyl-glutamyl-histidyl-aspartic acid fluoromethyl ketone inhibits the reaction [isoliquiritigenin results in increased cleavage of PARP1 protein] CTD PMID:23747687 PARP1 Human isoliquiritigenin increases cleavage EXP 6480464 isoliquiritigenin results in increased cleavage of PARP1 protein CTD PMID:23747687 PARP1 Human isoprenaline increases cleavage ISO Parp1 (Mus musculus) 6480464 Isoproterenol results in increased cleavage of PARP1 protein CTD PMID:31712309 PARP1 Human isoprenaline multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 erdosteine affects the reaction [Isoproterenol results in increased expression of PARP1 protein] CTD PMID:33210414 PARP1 Human isoprenaline increases expression ISO Parp1 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of PARP1 protein CTD PMID:33210414 PARP1 Human isoprenaline multiple interactions ISO Parp1 (Mus musculus) 6480464 BMP10 protein inhibits the reaction [Isoproterenol results in increased cleavage of PARP1 protein] CTD PMID:31712309 PARP1 Human isoprenaline decreases expression EXP 6480464 Isoproterenol results in decreased expression of PARP1 protein CTD PMID:29438734 PARP1 Human isoquinoline-1,5-diol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 1 and 5-dihydroxyisoquinoline inhibits the reaction [Vancomycin results in increased expression of PARP1 protein] CTD PMID:19833176 PARP1 Human isoquinoline-1,5-diol decreases activity EXP 6480464 1 and 5-dihydroxyisoquinoline results in decreased activity of PARP1 protein CTD PMID:25517228 PARP1 Human isoquinoline-1,5-diol multiple interactions EXP 6480464 1 more ... CTD PMID:25517228 PARP1 Human isoquinoline-1,5-diol decreases expression ISO Parp1 (Rattus norvegicus) 6480464 1 and 5-dihydroxyisoquinoline results in decreased expression of PARP1 protein CTD PMID:12824290 PARP1 Human isorhamnetin increases cleavage EXP 6480464 3-methylquercetin results in increased cleavage of PARP1 protein CTD PMID:22992727 PARP1 Human ivermectin increases expression EXP 6480464 Ivermectin results in increased expression of PARP1 protein modified form CTD PMID:28811376 PARP1 Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of PARP1 protein CTD PMID:32959892 PARP1 Human jaceosidin increases cleavage EXP 6480464 jaceosidin results in increased cleavage of PARP1 protein CTD PMID:27729209 PARP1 Human jaceosidin multiple interactions EXP 6480464 benzyloxycarbonyl-valyl-alanyl-aspartic acid analog inhibits the reaction [jaceosidin results in increased cleavage of PARP1 protein] more ... CTD PMID:27729209 PARP1 Human JBIR-99 decreases expression EXP 6480464 JBIR-99 results in decreased expression of PARP1 protein CTD PMID:31433962 PARP1 Human juglone multiple interactions EXP 6480464 [juglone co-treated with Ascorbic Acid] results in increased degradation of PARP1 protein CTD PMID:29992683 PARP1 Human kaempferol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 kaempferol inhibits the reaction [Doxorubicin results in increased cleavage of PARP1 protein] CTD PMID:22155320 PARP1 Human kaempferol increases cleavage EXP 6480464 kaempferol results in increased cleavage of PARP1 protein CTD PMID:16014620 PARP1 Human kaempferol multiple interactions EXP 6480464 3' and 4'-dihydroxyflavone analog inhibits the reaction [kaempferol results in increased cleavage of PARP1 protein] CTD PMID:16014620 PARP1 Human kahweol multiple interactions EXP 6480464 kahweol inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein] CTD PMID:31306736 PARP1 Human kahweol increases cleavage EXP 6480464 kahweol results in increased cleavage of PARP1 protein CTD PMID:30205135 PARP1 Human kainic acid increases activity ISO Parp1 (Rattus norvegicus) 6480464 Kainic Acid results in increased activity of PARP1 protein CTD PMID:28704930 PARP1 Human ketoconazole increases expression EXP 6480464 Ketoconazole results in increased expression of PARP1 mRNA CTD PMID:36621641 PARP1 Human L-1,4-dithiothreitol multiple interactions ISO Parp1 (Mus musculus) 6480464 Dithiothreitol inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:11035063 PARP1 Human L-1,4-dithiothreitol multiple interactions EXP 6480464 Dithiothreitol inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein] and Dithiothreitol inhibits the reaction [withaferin A results in increased cleavage of PARP1 protein] CTD PMID:18022205 and PMID:20438634 PARP1 Human L-ascorbic acid multiple interactions EXP 6480464 [juglone co-treated with Ascorbic Acid] results in increased degradation of PARP1 protein more ... CTD PMID:16407847 more ... PARP1 Human L-ascorbic acid multiple interactions ISO Parp1 (Mus musculus) 6480464 [Ascorbic Acid co-treated with Dexamethasone co-treated with beta-glycerophosphoric acid] results in increased expression of PARP1 mRNA more ... CTD PMID:26492236 PARP1 Human L-ascorbic acid multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Ascorbic Acid inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] and Ascorbic Acid inhibits the reaction [Potassium Dichromate results in increased cleavage of PARP1 protein] CTD PMID:19433269 and PMID:21262251 PARP1 Human L-ascorbic acid 2-phosphate multiple interactions EXP 6480464 [Dexamethasone co-treated with ascorbate-2-phosphate co-treated with beta-glycerophosphoric acid co-treated with Cholecalciferol] results in increased expression of PARP1 protein modified form more ... CTD PMID:22940495 PARP1 Human L-gamma-glutamyl-L-cysteine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 AKT activator SC79 inhibits the reaction [gamma-glutamylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of PARP1 protein]] more ... CTD PMID:34767868 PARP1 Human lactucin increases cleavage EXP 6480464 lactucin results in increased cleavage of PARP1 protein CTD PMID:34302634 and PMID:36364182 PARP1 Human lactucin multiple interactions EXP 6480464 benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [lactucin results in increased cleavage of PARP1 protein] and CFLAR protein inhibits the reaction [lactucin results in increased cleavage of PARP1 protein] CTD PMID:34302634 PARP1 Human lactulose multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Lactulose inhibits the reaction [Methamphetamine results in increased expression of PARP1 protein modified form] CTD PMID:30450033 PARP1 Human lapatinib multiple interactions EXP 6480464 2-(4-nitrophenyl)-4-(4-fluorophenyl)-5-(4-pyridinyl)-1H-imidazole inhibits the reaction [Lapatinib results in increased cleavage of PARP1 protein] more ... CTD PMID:25981168 more ... PARP1 Human lapatinib increases cleavage EXP 6480464 Lapatinib results in increased cleavage of PARP1 protein CTD PMID:25221644 and PMID:29387217 PARP1 Human lead diacetate decreases expression ISO Parp1 (Mus musculus) 6480464 lead acetate results in decreased expression of PARP1 mRNA CTD PMID:21829687 PARP1 Human lead diacetate increases expression ISO Parp1 (Rattus norvegicus) 6480464 lead acetate results in increased expression of PARP1 mRNA CTD PMID:28283887 PARP1 Human lead diacetate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 2-chloro-5-nitrobenzanilide inhibits the reaction [[lead acetate co-treated with Cadmium Chloride] results in increased expression of PARP1 mRNA] more ... CTD PMID:28283887 PARP1 Human lead diacetate increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 lead acetate results in increased cleavage of PARP1 protein CTD PMID:28283887 PARP1 Human lead(0) affects expression EXP 6480464 Lead affects the expression of PARP1 mRNA CTD PMID:28903495 PARP1 Human lead(0) multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human LGK974 multiple interactions EXP 6480464 LGK974 inhibits the reaction [Paraquat results in increased cleavage of PARP1 protein] CTD PMID:30205152 PARP1 Human Licochalcone A increases cleavage EXP 6480464 licochalcone A results in increased cleavage of PARP1 protein CTD PMID:30983163 and PMID:38308464 PARP1 Human Licochalcone A multiple interactions EXP 6480464 HSPA5 protein affects the reaction [licochalcone A results in increased cleavage of PARP1 protein] CTD PMID:38308464 PARP1 Human Licochalcone B multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [licochalcone B results in increased cleavage of PARP1 protein] more ... CTD PMID:35948134 PARP1 Human Licochalcone B increases cleavage EXP 6480464 licochalcone B results in increased cleavage of PARP1 protein CTD PMID:35948134 PARP1 Human licoricidin increases cleavage EXP 6480464 licoricidin results in increased cleavage of PARP1 protein CTD PMID:37013980 PARP1 Human lignan increases cleavage EXP 6480464 Lignans analog results in increased cleavage of PARP1 protein CTD PMID:26620693 PARP1 Human linsidomine multiple interactions ISO Parp1 (Mus musculus) 6480464 Selegiline inhibits the reaction [linsidomine results in decreased expression of PARP1 protein] CTD PMID:12880480 PARP1 Human linsidomine increases cleavage EXP 6480464 linsidomine results in increased cleavage of PARP1 protein CTD PMID:34519134 PARP1 Human linsidomine decreases activity EXP 6480464 linsidomine results in decreased activity of PARP1 protein CTD PMID:31152818 PARP1 Human linsidomine multiple interactions EXP 6480464 [bosutinib co-treated with linsidomine] affects the expression of PARP1 protein more ... CTD PMID:31152818 and PMID:34519134 PARP1 Human linsidomine decreases folding EXP 6480464 linsidomine results in decreased folding of PARP1 protein CTD PMID:31152818 PARP1 Human linsidomine decreases expression ISO Parp1 (Mus musculus) 6480464 linsidomine results in decreased expression of PARP1 protein CTD PMID:12880480 PARP1 Human lipopolysaccharide multiple interactions ISO Parp1 (Mus musculus) 6480464 [[Galactosamine co-treated with Lipopolysaccharides] results in increased cleavage of and results in increased activity of CASP3 protein] which results in increased cleavage of PARP1 protein more ... CTD PMID:11818323 more ... PARP1 Human lipopolysaccharide multiple interactions EXP 6480464 3 more ... CTD PMID:23011206 PARP1 Human lipopolysaccharide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Sialic Acids inhibits the reaction [Lipopolysaccharides results in increased expression of PARP1 protein] CTD PMID:24973090 PARP1 Human lipopolysaccharide increases expression ISO Parp1 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of PARP1 protein CTD PMID:24973090 PARP1 Human lipopolysaccharide increases expression ISO Parp1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of PARP1 protein modified form CTD PMID:23170834 PARP1 Human lithium atom multiple interactions EXP 6480464 Lithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:17849503 PARP1 Human lithium chloride multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-chloroacetylindole affects the reaction [[Pilocarpine co-treated with Lithium Chloride] affects the expression of PARP1 protein] more ... CTD PMID:27658547 more ... PARP1 Human lithium chloride multiple interactions EXP 6480464 Lithium Chloride inhibits the reaction [hydroquinone results in increased cleavage of PARP1 protein] and Lithium Chloride inhibits the reaction [quinocetone results in increased expression of PARP1 protein modified form] CTD PMID:28343033 and PMID:28886972 PARP1 Human lithium hydride multiple interactions EXP 6480464 Lithium inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] CTD PMID:17849503 PARP1 Human lithocholic acid multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [Lithocholic Acid analog results in increased activity of PARP1 protein] CTD PMID:2120135 PARP1 Human lithocholic acid increases activity EXP 6480464 Lithocholic Acid analog results in increased activity of PARP1 protein CTD PMID:2120135 PARP1 Human LM-1685 multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [[LM-1685 co-treated with carboxyamido-triazole] results in increased cleavage of PARP1 protein] CTD PMID:15867384 PARP1 Human Lobetyolin increases cleavage EXP 6480464 lobetyolin results in increased cleavage of PARP1 protein CTD PMID:34075790 PARP1 Human Longikaurin A increases expression EXP 6480464 longikaurin A results in increased expression of PARP1 protein modified form CTD PMID:28801140 PARP1 Human losartan multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Losartan inhibits the reaction [AGT protein results in increased expression of PARP1 protein] CTD PMID:21613793 PARP1 Human losartan multiple interactions ISO Parp1 (Mus musculus) 6480464 Losartan inhibits the reaction [AGT protein results in increased activity of PARP1 protein] CTD PMID:15502880 PARP1 Human lovastatin increases cleavage EXP 6480464 Lovastatin analog results in increased cleavage of PARP1 protein CTD PMID:26863638 PARP1 Human Lupiwighteone increases cleavage EXP 6480464 lupiwighteone results in increased cleavage of PARP1 protein CTD PMID:31604113 PARP1 Human luteolin increases cleavage EXP 6480464 Luteolin results in increased cleavage of PARP1 protein CTD PMID:12168845 more ... PARP1 Human luteolin multiple interactions ISO Parp1 (Mus musculus) 6480464 Luteolin inhibits the reaction [Tunicamycin results in increased expression of PARP1 protein modified form] CTD PMID:32407927 PARP1 Human luteolin multiple interactions EXP 6480464 [Luteolin co-treated with Paclitaxel] results in decreased expression of PARP1 protein more ... CTD PMID:24525192 more ... PARP1 Human luteolin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Luteolin results in increased cleavage of PARP1 protein CTD PMID:31201582 PARP1 Human luteolin 7-O-beta-D-glucoside multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [luteolin-7-glucoside results in increased cleavage of PARP1 protein] more ... CTD PMID:34165247 PARP1 Human luteolin 7-O-beta-D-glucoside increases cleavage EXP 6480464 luteolin-7-glucoside results in increased cleavage of PARP1 protein CTD PMID:34165247 PARP1 Human LY294002 multiple interactions ISO Parp1 (Mus musculus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein] CTD PMID:14687664 and PMID:23143138 PARP1 Human LY294002 multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein] CTD PMID:27658547 PARP1 Human LY294002 increases cleavage EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased cleavage of PARP1 protein CTD PMID:14688022 more ... PARP1 Human LY294002 multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Capsaicin results in increased cleavage of and results in increased activity of PARP1 protein] more ... CTD PMID:19261616 more ... PARP1 Human lycopene multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 lycopene inhibits the reaction [decamethrin results in increased activity of PARP1 protein] CTD PMID:23076637 PARP1 Human lysophosphatidylethanolamine multiple interactions EXP 6480464 lysophosphatidylethanolamine analog inhibits the reaction [cobaltous chloride results in increased activity of PARP1 protein] CTD PMID:25125499 PARP1 Human Maduramicin increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 maduramicin results in increased cleavage of PARP1 protein CTD PMID:29047155 PARP1 Human Maduramicin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 benzyloxycarbonylvalyl-alanyl-aspartyl fluoromethyl ketone inhibits the reaction [maduramicin results in increased cleavage of PARP1 protein] CTD PMID:29047155 PARP1 Human malathion multiple interactions ISO Parp1 (Mus musculus) 6480464 Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein] CTD PMID:29027213 PARP1 Human malathion increases cleavage ISO Parp1 (Mus musculus) 6480464 Malathion results in increased cleavage of PARP1 protein CTD PMID:29027213 PARP1 Human malvidin increases cleavage EXP 6480464 malvidin results in increased cleavage of PARP1 protein CTD PMID:15964118 PARP1 Human manganese atom multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein more ... CTD PMID:25791630 PARP1 Human manganese atom multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human manganese atom increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Manganese results in increased cleavage of PARP1 protein CTD PMID:25448048 and PMID:25791630 PARP1 Human manganese(0) increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Manganese results in increased cleavage of PARP1 protein CTD PMID:25448048 and PMID:25791630 PARP1 Human manganese(0) multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human manganese(0) multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Manganese co-treated with NGF protein] results in increased cleavage of PARP1 protein more ... CTD PMID:25791630 PARP1 Human manganese(II) chloride multiple interactions ISO Parp1 (Mus musculus) 6480464 [Plant Extracts co-treated with manganese chloride] affects the cleavage of PARP1 protein CTD PMID:26064043 PARP1 Human manganese(II) chloride multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 benzyloxycarbonyl-isoleucyl-glutamyl-threonyl-aspartic acid fluoromethyl ketone inhibits the reaction [manganese chloride results in increased cleavage of PARP1 protein] CTD PMID:21704098 PARP1 Human manganese(II) chloride increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 manganese chloride results in increased cleavage of PARP1 protein CTD PMID:21704098 PARP1 Human manumycin A increases cleavage EXP 6480464 manumycin results in increased cleavage of PARP1 and manumycin results in increased cleavage of PARP1 protein CTD PMID:14625852 and PMID:19409983 PARP1 Human manumycin A multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [manumycin results in increased cleavage of PARP1] and Quercetin promotes the reaction [manumycin results in increased cleavage of PARP1 protein] CTD PMID:14625852 and PMID:19409983 PARP1 Human Melarsoprol increases cleavage EXP 6480464 Melarsoprol results in increased cleavage of PARP1 protein CTD PMID:15314284 PARP1 Human melatonin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Melatonin inhibits the reaction [Doxorubicin results in increased expression of PARP1 protein modified form] and Melatonin inhibits the reaction [Tenofovir results in increased expression of PARP1 protein] CTD PMID:29966675 and PMID:33146023 PARP1 Human melatonin multiple interactions ISO Parp1 (Mus musculus) 6480464 Melatonin inhibits the reaction [Atrazine results in increased cleavage of PARP1 protein] CTD PMID:25259610 PARP1 Human melittin multiple interactions ISO Parp1 (Mus musculus) 6480464 Melitten inhibits the reaction [TGFB1 protein results in increased cleavage of PARP1 protein] CTD PMID:21871910 PARP1 Human menadione multiple interactions EXP 6480464 [sodium arsenite co-treated with Vitamin K 3] results in increased cleavage of PARP1 protein CTD PMID:19082730 PARP1 Human menadione affects response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 protein affects the susceptibility to Vitamin K 3 CTD PMID:21124846 PARP1 Human menaquinone increases cleavage EXP 6480464 Vitamin K 2 results in increased cleavage of PARP1 protein CTD PMID:29432837 PARP1 Human mercury atom multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human mercury dichloride increases cleavage EXP 6480464 Mercuric Chloride results in increased cleavage of PARP1 protein CTD PMID:11068922 more ... PARP1 Human mercury dichloride multiple interactions ISO Parp1 (Mus musculus) 6480464 [Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein and Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein] CTD PMID:22909951 PARP1 Human mercury(0) multiple interactions EXP 6480464 [Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein and Luteolin inhibits the reaction [[Lead co-treated with Cadmium co-treated with Mercury co-treated with Copper co-treated with Zinc co-treated with Manganese co-treated with Chromium co-treated with Nickel] results in increased cleavage of PARP1 protein] CTD PMID:29115570 PARP1 Human mesalamine increases cleavage EXP 6480464 Mesalamine results in increased cleavage of PARP1 protein CTD PMID:12663503 PARP1 Human metformin multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Dietary Fats results in increased expression of and results in increased cleavage of PARP1 protein] CTD PMID:27551045 PARP1 Human metformin increases cleavage EXP 6480464 Metformin results in increased cleavage of PARP1 protein CTD PMID:35350904 PARP1 Human metformin multiple interactions ISO Parp1 (Mus musculus) 6480464 Deoxyglucose promotes the reaction [Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form]] and Metformin inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein modified form] CTD PMID:29095437 PARP1 Human metformin multiple interactions EXP 6480464 [epothilone A co-treated with Metformin] results in increased expression of PARP1 mRNA more ... CTD PMID:29117515 and PMID:35350904 PARP1 Human metformin increases expression EXP 6480464 Metformin results in increased expression of PARP1 mRNA CTD PMID:29117515 PARP1 Human methamphetamine multiple interactions EXP 6480464 BBC3 protein affects the reaction [Methamphetamine results in decreased cleavage of PARP1 protein] more ... CTD PMID:25523949 more ... PARP1 Human methamphetamine increases cleavage EXP 6480464 Methamphetamine results in increased cleavage of PARP1 protein CTD PMID:25523949 and PMID:31059759 PARP1 Human methamphetamine increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Methamphetamine results in increased cleavage of PARP1 protein CTD PMID:25631491 more ... PARP1 Human methamphetamine increases activity ISO Parp1 (Rattus norvegicus) 6480464 Methamphetamine results in increased activity of PARP1 protein CTD PMID:25127757 PARP1 Human methamphetamine increases expression ISO Parp1 (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of PARP1 protein modified form CTD PMID:26825372 more ... PARP1 Human methamphetamine decreases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Methamphetamine results in decreased cleavage of PARP1 protein CTD PMID:26524635 PARP1 Human methamphetamine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 3-methyladenine promotes the reaction [Methamphetamine results in increased cleavage of PARP1 protein] more ... CTD PMID:25127757 more ... PARP1 Human methamphetamine decreases cleavage EXP 6480464 Methamphetamine results in decreased cleavage of PARP1 protein CTD PMID:26524635 PARP1 Human methotrexate multiple interactions EXP 6480464 ESRRA protein inhibits the reaction [Methotrexate results in increased cleavage of PARP1 protein] CTD PMID:24967384 PARP1 Human methotrexate multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 DHFR protein inhibits the reaction [Methotrexate results in increased cleavage of PARP1 protein] and Folic Acid inhibits the reaction [Methotrexate results in increased cleavage of PARP1 protein] CTD PMID:30502384 PARP1 Human methotrexate increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 Methotrexate results in increased cleavage of PARP1 protein CTD PMID:30502384 PARP1 Human methotrexate increases cleavage EXP 6480464 Methotrexate results in increased cleavage of PARP1 protein CTD PMID:17286800 and PMID:24967384 PARP1 Human methoxsalen multiple interactions EXP 6480464 Methoxsalen inhibits the reaction [Aflatoxin B1 results in increased expression of PARP1 protein modified form] CTD PMID:22743290 PARP1 Human methoxyacetic acid multiple interactions EXP 6480464 [1-aminomethylphosphonic acid co-treated with methoxyacetic acid] results in increased cleavage of PARP1 protein CTD PMID:26006246 PARP1 Human methyl beta-cyclodextrin multiple interactions EXP 6480464 methyl-beta-cyclodextrin inhibits the reaction [Ursodeoxycholic Acid results in increased cleavage of PARP1 protein] CTD PMID:21362627 PARP1 Human methyl caffeate multiple interactions EXP 6480464 methyl caffeate binds to and results in increased activity of PARP1 protein CTD PMID:26415618 PARP1 Human methyl methanesulfonate affects response to substance EXP 6480464 PARP1 protein affects the susceptibility to Methyl Methanesulfonate CTD PMID:19111594 PARP1 Human methyl methanesulfonate decreases expression EXP 6480464 Methyl Methanesulfonate results in decreased expression of PARP1 mRNA CTD PMID:23649840 PARP1 Human methylglyoxal increases cleavage EXP 6480464 Pyruvaldehyde results in increased cleavage of PARP1 protein CTD PMID:31254498 and PMID:33930484 PARP1 Human methylglyoxal multiple interactions EXP 6480464 naringenin inhibits the reaction [Pyruvaldehyde results in increased cleavage of PARP1 protein] more ... CTD PMID:31254498 and PMID:33930484 PARP1 Human methylisothiazolinone increases cleavage EXP 6480464 2-methyl-4-isothiazolin-3-one results in increased cleavage of PARP1 protein CTD PMID:29110394 PARP1 Human methylmercury chloride increases cleavage EXP 6480464 methylmercuric chloride results in increased cleavage of PARP1 protein CTD PMID:11068922 PARP1 Human methylmercury chloride increases expression ISO Parp1 (Mus musculus) 6480464 methylmercuric chloride results in increased expression of PARP1 protein modified form CTD PMID:31330229 PARP1 Human methylmercury chloride multiple interactions ISO Parp1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of PARP1 protein] and AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased expression of PARP1 protein modified form] CTD PMID:31330229 PARP1 Human methylseleninic acid multiple interactions EXP 6480464 [2 more ... CTD PMID:16204082 more ... PARP1 Human methylseleninic acid increases cleavage EXP 6480464 methylselenic acid results in increased cleavage of PARP1 protein CTD PMID:15845651 more ... PARP1 Human methylseleninic acid increases cleavage ISO Parp1 (Mus musculus) 6480464 methylselenic acid results in increased cleavage of PARP1 protein CTD PMID:19276161 PARP1 Human metipranolol multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Metipranolol inhibits the reaction [Zinc results in decreased expression of PARP1 protein] and Metipranolol inhibits the reaction [Zinc Sulfate results in decreased expression of PARP1 protein] CTD PMID:16799065 PARP1 Human metoclopramide multiple interactions ISO Parp1 (Mus musculus) 6480464 Metoclopramide inhibits the reaction [Malathion results in increased cleavage of PARP1 protein] and Metoclopramide inhibits the reaction [Paraoxon results in increased cleavage of PARP1 protein] CTD PMID:29027213 PARP1 Human mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]] more ... CTD PMID:20045437 and PMID:21910007 PARP1 Human Mezerein multiple interactions EXP 6480464 3-aminobenzamide inhibits the reaction [mezerein results in increased activity of PARP1 protein] CTD PMID:2120135 PARP1 Human Mezerein increases activity EXP 6480464 mezerein results in increased activity of PARP1 protein CTD PMID:2120135 and PMID:2126186 PARP1 Human microcystin-LR increases cleavage ISO Parp1 (Mus musculus) 6480464 cyanoginosin LR results in increased cleavage of PARP1 protein CTD PMID:21684301 PARP1 Human microcystin-LR multiple interactions EXP 6480464 [cyanoginosin LR inhibits the reaction [PARP1 protein binds to TIMELESS protein]] promotes the reaction [CGAS protein binds to PARP1 protein] more ... CTD PMID:36435412 PARP1 Human microcystin-LR multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 pifithrin inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein] CTD PMID:31157505 PARP1 Human microcystin-LR increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 cyanoginosin LR results in increased cleavage of PARP1 protein CTD PMID:31157505 PARP1 Human microcystin-LR multiple interactions ISO Parp1 (Mus musculus) 6480464 sulforaphane inhibits the reaction [cyanoginosin LR results in increased cleavage of PARP1 protein] CTD PMID:21684301 PARP1 Human mifepristone multiple interactions ISO Parp1 (Mus musculus) 6480464 Mifepristone inhibits the reaction [Dexamethasone results in increased cleavage of PARP1 protein] CTD PMID:16644695 PARP1 Human mifepristone increases cleavage EXP 6480464 Mifepristone results in increased cleavage of PARP1 protein CTD PMID:16525653 PARP1 Human mitomycin C multiple interactions EXP 6480464 CDKN1A mutant form inhibits the reaction [Chloramphenicol inhibits the reaction [Mitomycin results in increased activity of PARP1 protein]] more ... CTD PMID:15905168 and PMID:24124520 PARP1 Human mitomycin C decreases response to substance EXP 6480464 PARP1 protein results in decreased susceptibility to Mitomycin CTD PMID:28757444 PARP1 Human mitomycin C increases cleavage EXP 6480464 Mitomycin results in increased cleavage of PARP1 protein CTD PMID:24124520 PARP1 Human mitomycin C increases activity EXP 6480464 Mitomycin results in increased activity of PARP1 protein CTD PMID:15905168 PARP1 Human mitoxantrone multiple interactions EXP 6480464 [Cladribine co-treated with Cyclophosphamide co-treated with Mitoxantrone] results in decreased expression of PARP1 protein more ... CTD PMID:15582267 and PMID:8840993 PARP1 Human MK-2206 multiple interactions EXP 6480464 [mirdametinib co-treated with MK 2206] results in increased cleavage of PARP1 protein more ... CTD PMID:27634878 PARP1 Human monensin A increases cleavage EXP 6480464 Monensin results in increased cleavage of PARP1 protein CTD PMID:30718715 PARP1 Human monocrotophos increases expression EXP 6480464 Monocrotophos results in increased expression of PARP1 mRNA and Monocrotophos results in increased expression of PARP1 protein CTD PMID:28887667 PARP1 Human morin increases expression EXP 6480464 morin results in increased expression of PARP1 mRNA CTD PMID:28689916 PARP1 Human morpholines multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein] and Acetylcysteine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein] CTD PMID:24875536 PARP1 Human morpholines increases cleavage EXP 6480464 Morpholines analog results in increased cleavage of PARP1 protein CTD PMID:24875536 PARP1 Human morusin increases cleavage EXP 6480464 morusin results in increased cleavage of PARP1 protein CTD PMID:33035517 and PMID:37443484 PARP1 Human morusin multiple interactions EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [morusin results in increased cleavage of PARP1 protein] more ... CTD PMID:33035517 PARP1 Human myo-inositol hexakisphosphate multiple interactions EXP 6480464 Phytic Acid inhibits the reaction [Asbestos more ... CTD PMID:11217149 PARP1 Human myricetin increases cleavage EXP 6480464 myricetin results in increased cleavage of PARP1 protein CTD PMID:15748703 and PMID:29698783 PARP1 Human myricetin decreases activity EXP 6480464 myricetin results in decreased activity of PARP1 protein CTD PMID:17884996 PARP1 Human myriocin multiple interactions EXP 6480464 thermozymocidin inhibits the reaction [resveratrol results in increased cleavage of PARP1 protein] CTD PMID:24264887 PARP1 Human myristicin increases cleavage EXP 6480464 myristicin results in increased cleavage of PARP1 protein CTD PMID:24792648 PARP1 Human N(gamma)-nitro-L-arginine methyl ester multiple interactions ISO Parp1 (Mus musculus) 6480464 NG-Nitroarginine Methyl Ester inhibits the reaction [AGT protein results in increased activity of PARP1 protein] CTD PMID:15502880 PARP1 Human N(omega)-methyl-L-arginine multiple interactions EXP 6480464 omega-N-Methylarginine inhibits the reaction [[Lipopolysaccharides co-treated with IFNG protein] results in increased expression of PARP1 protein] CTD PMID:23011206 PARP1 Human N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine decreases activity EXP 6480464 N more ... CTD PMID:24275069 PARP1 Human N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions ISO Parp1 (Mus musculus) 6480464 N more ... CTD PMID:22253048 PARP1 Human N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine multiple interactions EXP 6480464 N more ... CTD PMID:15966574 more ... PARP1 Human N,N-dimethylformamide multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased cleavage of PARP1 protein CTD PMID:20097184 PARP1 Human N,N-dimethylsphingosine multiple interactions EXP 6480464 [Bortezomib co-treated with N and N-dimethylsphingosine] results in increased cleavage of PARP1 protein CTD PMID:21195056 PARP1 Human N-acetyl-L-cysteine multiple interactions ISO Parp1 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [1 more ... CTD PMID:14687664 more ... PARP1 Human N-acetyl-L-cysteine decreases expression EXP 6480464 Acetylcysteine results in decreased expression of PARP1 protein modified form CTD PMID:31433961 PARP1 Human N-acetyl-L-cysteine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein] more ... CTD PMID:11470263 more ... PARP1 Human N-acetyl-L-cysteine multiple interactions EXP 127284846 N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of PARP protein in the stomach) RGD PARP1 Human N-acetyl-L-cysteine increases cleavage ISO Parp1 (Mus musculus) 6480464 Acetylcysteine results in increased cleavage of PARP1 protein CTD PMID:15375156 PARP1 Human N-acetyl-L-cysteine multiple interactions EXP 6480464 [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein] more ... CTD PMID:14660655 more ... PARP1 Human N-acetylsphingosine increases activity EXP 6480464 N-acetylsphingosine results in increased activity of PARP1 protein CTD PMID:24420784 PARP1 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases cleavage ISO Parp1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein CTD PMID:20100472 and PMID:34418242 PARP1 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases cleavage EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased cleavage of PARP1 protein CTD PMID:15498850 more ... PARP1 Human N-methyl-4-phenylpyridinium increases cleavage EXP 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein CTD PMID:20946892 more ... PARP1 Human N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PARP1 protein modified form CTD PMID:28481321 and PMID:31342299 PARP1 Human N-methyl-4-phenylpyridinium increases cleavage ISO Parp1 (Rattus norvegicus) 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein CTD PMID:24875324 PARP1 Human N-methyl-4-phenylpyridinium multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Plant Preparations inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein] and Polysaccharides inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein] CTD PMID:24875324 PARP1 Human N-methyl-4-phenylpyridinium increases cleavage ISO Parp1 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased cleavage of PARP1 protein CTD PMID:20946892 PARP1 Human N-methyl-4-phenylpyridinium multiple interactions EXP 6480464 8-phenyl-6a more ... CTD PMID:20946892 more ... PARP1 Human N-methyl-4-phenylpyridinium multiple interactions ISO Parp1 (Mus musculus) 6480464 8-phenyl-6a more ... CTD PMID:20946892 PARP1 Human N-methyl-4-phenylpyridinium increases expression ISO Parp1 (Mus musculus) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PARP1 protein CTD PMID:26558463 PARP1 Human N-methyl-D-aspartic acid increases ADP-ribosylation ISO Parp1 (Rattus norvegicus) 6480464 N-Methylaspartate results in increased ADP-ribosylation of PARP1 protein CTD PMID:16903875 PARP1 Human N-methyl-N'-nitro-N-nitrosoguanidine multiple interactions ISO Parp1 (Mus musculus) 6480464 [benzamide results in decreased activity of PARP1 protein] which results in decreased susceptibility to Methylnitronitrosoguanidine more ... CTD PMID:11593040 more ... PARP1 Human N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO Parp1 (Mus musculus) 6480464 Methylnitronitrosoguanidine results in increased expression of PARP1 protein CTD PMID:26954031 PARP1 Human N-methyl-N'-nitro-N-nitrosoguanidine increases response to substance EXP 6480464 PARP1 protein results in increased susceptibility to Methylnitronitrosoguanidine CTD PMID:22001597 PARP1 Human N-methyl-N'-nitro-N-nitrosoguanidine affects cleavage ISO Parp1 (Mus musculus) 6480464 Methylnitronitrosoguanidine affects the cleavage of PARP1 protein CTD PMID:20434464 PARP1 Human N-methyl-N'-nitro-N-nitrosoguanidine increases activity ISO Parp1 (Mus musculus) 6480464 Methylnitronitrosoguanidine results in increased activity of PARP1 protein CTD PMID:11593040 PARP1 Human N-methyl-N-nitrosourea increases response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 gene mutant form results in increased susceptibility to Methylnitrosourea CTD PMID:15282315 PARP1 Human N-methyl-N-nitrosourea multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 Niacinamide inhibits the reaction [Methylnitrosourea results in increased activity of PARP1 protein] CTD PMID:16168987 PARP1 Human N-methyl-N-nitrosourea increases activity ISO Parp1 (Rattus norvegicus) 6480464 Methylnitrosourea results in increased activity of PARP1 protein CTD PMID:16168987 PARP1 Human N-methyl-N-nitrosourea affects response to substance ISO Parp1 (Mus musculus) 6480464 PARP1 protein affects the susceptibility to Methylnitrosourea CTD PMID:11850828 PARP1 Human N-methyl-N-nitrosourea multiple interactions ISO Parp1 (Mus musculus) 6480464 PARP1 protein affects the reaction [Methylnitrosourea affects the activity of TRP53 protein] more ... CTD PMID:11850828 and PMID:16052507 PARP1 Human N-methylnicotinate multiple interactions EXP 6480464 [trigonelline co-treated with Cisplatin] results in increased cleavage of PARP1 protein and [trigonelline co-treated with Etoposide] results in increased cleavage of PARP1 protein CTD PMID:33148531 PARP1 Human N-methylnicotinate multiple interactions ISO Parp1 (Mus musculus) 6480464 trigonelline inhibits the reaction [Palmitic Acid results in increased cleavage of PARP1 protein] CTD PMID:30208301 PARP1 Human N-Nitrosodi-n-butylamine increases cleavage EXP 6480464 dibutylnitrosamine results in increased cleavage of PARP1 protein CTD PMID:17929238 PARP1 Human N-nitrosodiethylamine multiple interactions ISO Parp1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of PARP1 mRNA CTD PMID:17602206 PARP1 Human N-nitrosopiperidine increases cleavage EXP 6480464 N-nitrosopiperidine results in increased cleavage of PARP1 protein CTD PMID:17929238 PARP1 Human N-tosyl-L-phenylalanyl chloromethyl ketone multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein] CTD PMID:19679660 PARP1 Human N-tosyl-L-phenylalanyl chloromethyl ketone increases cleavage EXP 6480464 Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein CTD PMID:19679660 PARP1 Human N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Rotenone results in increased cleavage of PARP1 protein] CTD PMID:19723537 PARP1 Human NAD zwitterion multiple interactions EXP 6480464 [2 more ... CTD PMID:17669606 more ... PARP1 Human 
