BDNF (brain derived neurotrophic factor) - Rat Genome Database

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Pathways
Gene: BDNF (brain derived neurotrophic factor) Homo sapiens
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Symbol: BDNF
Name: brain derived neurotrophic factor
RGD ID: 731027
HGNC Page HGNC:1033
Description: Predicted to enable growth factor activity and nerve growth factor receptor binding activity. Involved in nervous system development and positive regulation of nervous system development. Predicted to be located in perinuclear region of cytoplasm and secretory granule. Predicted to be active in several cellular components, including glutamatergic synapse; hippocampal mossy fiber to CA3 synapse; and secretory vesicle. Implicated in several diseases, including alcohol dependence; cocaine dependence; cognitive disorder (multiple); congenital central hypoventilation syndrome; and neurodegenerative disease (multiple). Biomarker of several diseases, including lung disease (multiple); mood disorder (multiple); neurodegenerative disease (multiple); open-angle glaucoma (multiple); and opiate dependence (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: abrineurin; ANON2; brain-derived neurotrophic factor; BULN2; MGC34632; neurotrophic factor BDNF precursor form; neurotrophin; proBDNF
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381127,654,893 - 27,722,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1127,654,893 - 27,722,058 (-)Ensemblhg38GRCh38
GRCh371127,676,440 - 27,743,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,633,016 - 27,699,872 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341127,633,019 - 27,637,249NCBI
Celera1127,822,548 - 27,889,725 (-)NCBICelera
Cytogenetic Map11p14.1NCBI
HuRef1127,374,586 - 27,441,772 (-)NCBIHuRef
CHM1_11127,675,184 - 27,742,527 (-)NCBICHM1_1
T2T-CHM13v2.01127,795,301 - 27,862,460 (-)NCBIT2T-CHM13v2.0
JBrowse:




Disease Annotations     Click to see Annotation Detail View
acoustic neuroma  (IEP)
acute stress disorder  (ISO)
alcohol dependence  (IAGP,ISO)
alcohol use disorder  (IEP,ISO)
alcohol withdrawal syndrome  (IEP,ISO)
Alcohol-Related Disorders  (ISO)
Alcoholic Intoxication  (ISO)
alopecia  (IEP)
Alzheimer's disease  (EXP,IAGP,IEA,IEP,ISO)
amnestic disorder  (ISO)
amphetamine abuse  (EXP,ISO)
Amyloid Plaques  (ISO)
Anhedonia  (ISO)
anxiety disorder  (ISO)
Arthralgia  (ISO)
asthma  (IAGP,IDA,IEP)
Ataxia  (ISO)
atopic dermatitis  (IAGP,IEP)
attention deficit hyperactivity disorder  (ISO)
autism spectrum disorder  (EXP,IEP)
autistic disorder  (EXP)
bacterial meningitis  (ISO)
Binge Drinking  (ISO)
bipolar disorder  (EXP,IEA)
Body Weight  (EXP)
borna disease  (ISO)
Brain Injuries  (EXP,IEP)
brain ischemia  (EXP)
cannabis abuse  (ISO)
Cerebral Hemorrhage  (IMP)
Chronic Pain  (ISO)
cocaine abuse  (ISO)
cocaine dependence  (IDA,ISO)
Cocaine-Related Disorders  (EXP,ISO)
cognitive disorder  (IAGP,ISO)
colitis  (ISO)
color blindness  (IAGP)
congenital central hypoventilation syndrome  (IAGP)
cystitis  (ISO)
Deafness  (EXP,IDA,ISO)
depressive disorder  (EXP,IEP,ISO)
Diabetic Nephropathies  (ISO)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
Drug Eruptions  (ISO)
Dysbiosis  (ISO)
epilepsy  (EXP)
epilepsy with generalized tonic-clonic seizures  (EXP)
Experimental Autoimmune Encephalomyelitis  (ISO)
Experimental Diabetes Mellitus  (ISO)
Experimental Seizures  (ISO)
focal epilepsy  (IEA)
Frontotemporal Lobar Degeneration  (IAGP)
genetic disease  (IAGP)
glaucoma  (IDA,IMP,ISO)
Gliosis  (EXP)
Hearing Loss  (ISO)
Hearing Loss, Noise-Induced  (ISO)
heroin dependence  (EXP,IEP)
Huntington's disease  (IEP,IMP,ISO)
Hyperalgesia  (IDA,ISO)
Hyperoxia  (ISO)
hypertensive encephalopathy  (ISO)
hypothyroidism  (ISO)
Hypoxia  (EXP)
Inflammation  (EXP,ISO)
inner ear disease  (ISO)
intellectual disability  (EXP,IAGP)
intermediate coronary syndrome  (IEP)
interstitial lung disease  (IEP)
Intervertebral Disc Disease  (IEP)
Intervertebral Disc Displacement  (ISO)
intestinal disease  (ISO)
irritable bowel syndrome  (IEP)
keratoconus  (IEP)
Leukoencephalopathies  (ISO)
low tension glaucoma  (IEP)
major depressive disorder  (IEP)
Memory Disorders  (IAGP,IEP,ISO)
Metabolic Syndrome  (IEP)
middle cerebral artery infarction  (ISO)
mood disorder  (IEP)
morbid obesity  (EXP)
morphine dependence  (ISO)
morphine withdrawal syndrome  (ISO)
multiple sclerosis  (IEP)
Nasal Polyps  (IEP)
neovascular inflammatory vitreoretinopathy  (IEP)
Nerve Degeneration  (EXP,ISO)
Nerve Injuries  (ISO)
nervous system disease  (EXP)
nicotine dependence  (EXP,ISO)
obesity  (IAGP,IEP)
obsessive-compulsive disorder  (IAGP,ISO)
obstructive sleep apnea  (IDA)
opiate dependence  (IEP)
Optic Nerve Injuries  (IDA,ISO)
Pain  (ISO)
Parkinson's disease  (EXP,IAGP,IEA,IEP)
Parkinsonism  (IDA)
Peripheral Nerve Injuries  (ISO)
post-traumatic stress disorder  (IAGP,ISO)
Postoperative Cognitive Dysfunction  (IEP,ISO)
premature ejaculation  (ISO)
Prenatal Exposure Delayed Effects  (ISO)
Presbycusis  (ISO)
primary open angle glaucoma  (IEP)
psychotic disorder  (EXP)
pulmonary fibrosis  (IEP)
pulmonary sarcoidosis  (IEP)
Radiation Injuries  (ISO)
Referred Pain  (ISO)
Reperfusion Injury  (ISO)
Respiration Disorders  (ISO)
Respiratory Tract Infections  (IEP)
Retina Reperfusion Injury  (IDA)
retinal degeneration  (ISO)
rhinitis  (IAGP,ISO)
schizophrenia  (EXP,IEA)
sciatic neuropathy  (ISO)
Seasonal Allergic Rhinitis  (IEP)
sensorineural hearing loss  (ISO)
Sjogren's syndrome  (IEP)
Sleep Deprivation  (ISO)
Spinal Cord Injuries  (IMP,ISO)
Spinal Cord Reperfusion Injury  (ISO)
Starvation  (ISO)
status epilepticus  (EXP,IMP,ISO)
Stomach Neoplasms  (EXP)
Stroke  (ISO)
systemic scleroderma  (IEP)
Tinnitus  (IEP,ISO)
transient cerebral ischemia  (ISO)
traumatic brain injury  (ISO)
trigeminal neuralgia  (ISO)
type 2 diabetes mellitus  (IEP)
urticaria  (IEP)
vascular dementia  (ISO)
Visceral Pain  (ISO)
withdrawal disorder  (EXP,ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (ISO)
(+)-epicatechin-3-O-gallate  (EXP)
(+)-pilocarpine  (ISO)
(+)-syringaresinol beta-D-glucoside  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(20S)-ginsenoside Rg3  (EXP,ISO)
(R)-salsolinol  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-3,5-dihydroxyphenylglycine  (ISO)
(S)-AMPA  (ISO)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-bromopropane  (EXP,ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthol  (EXP)
13,14-dihydro-Delta(12)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,5-hexanedione  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (ISO)
2-palmitoylglycerol  (EXP)
3',5'-cyclic AMP  (EXP)
3,3',5,5'-tetrabromobisphenol A  (EXP,ISO)
3,4-dihydroxybenzoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
3-Methoxynobiletin  (ISO)
3-nitropropanoic acid  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (ISO)
4-[1-hydroxy-2-[4-(phenylmethyl)-1-piperidinyl]propyl]phenol  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxypsoralen  (ISO)
6-anilino-5,8-quinolinedione  (EXP)
6-Cyano-7-nitroquinoxaline-2,3-dione  (ISO)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
[6]-Shogaol  (ISO)
AB-Fubinaca  (ISO)
acetylsalicylic acid  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (EXP,ISO)
agathisflavone  (ISO)
agmatine  (ISO)
agomelatine  (ISO)
alcohol  (ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
alpha-D-galactose  (ISO)
alpha-pinene  (ISO)
alpha-Solamarine  (ISO)
aluminium hydroxide  (EXP)
AM-251  (ISO)
amantadine  (ISO)
amiodarone  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
aniracetam  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
apigenin  (ISO)
arachidonic acid  (EXP)
aristolochic acid A  (EXP)
Aroclor 1254  (EXP,ISO)
arsane  (EXP,ISO)
arsanilic acid  (ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (EXP)
arsenous acid  (EXP,ISO)
asiaticoside  (ISO)
Atractylone  (EXP)
atrazine  (EXP,ISO)
Bardoxolone methyl  (ISO)
Bay-K-8644  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
beta-D-glucosamine  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
bromocriptine  (ISO)
bucladesine  (EXP)
bupivacaine  (EXP)
buprenorphine  (ISO)
Butylbenzyl phthalate  (ISO)
Butylparaben  (ISO)
C60 fullerene  (ISO)
cabergoline  (EXP)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
calcitriol  (EXP)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
cannabidiol  (EXP,ISO)
capsaicin  (ISO)
carbamazepine  (ISO)
carbon dioxide  (ISO)
carbon monoxide  (ISO)
carbon nanotube  (ISO)
celastrol  (ISO)
CGP 52608  (EXP)
CGS-21680  (ISO)
chaetocin  (ISO)
chlorohydrocarbon  (EXP)
chloroprene  (ISO)
chlorpromazine  (EXP,ISO)
chlorpyrifos  (EXP,ISO)
cholesterol  (ISO)
choline  (ISO)
chondroitin sulfate  (EXP)
chrysin  (ISO)
cisplatin  (EXP,ISO)
Citreoviridin  (ISO)
clofibrate  (ISO)
clopidogrel  (EXP)
clozapine  (ISO)
cocaine  (EXP,ISO)
coenzyme Q10  (ISO)
colforsin daropate hydrochloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (ISO)
corticosterone  (ISO)
creatine  (ISO)
crocidolite asbestos  (EXP)
crocin-1  (ISO)
Cuprizon  (ISO)
curcumin  (ISO)
cyanocob(III)alamin  (ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyfluthrin  (ISO)
cypermethrin  (ISO)
daidzein 7-O-beta-D-glucoside  (ISO)
dantrolene  (ISO)
DDE  (EXP,ISO)
DDT  (ISO)
decabromodiphenyl ether  (ISO)
deguelin  (EXP,ISO)
dermatan sulfate  (EXP)
desferrioxamine B  (ISO)
desipramine  (ISO)
dexamethasone  (EXP,ISO)
diallyl disulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
diazepam  (ISO)
diazinon  (ISO)
dibutyl phthalate  (ISO)
dichloroacetic acid  (ISO)
diethyl phthalate  (ISO)
diethylstilbestrol  (EXP,ISO)
dihydroactinidiolide  (ISO)
dihydrolipoic acid  (EXP)
diisobutyl phthalate  (ISO)
diisononyl phthalate  (ISO)
diisopropyl fluorophosphate  (ISO)
dimethyl fumarate  (ISO)
dioxygen  (EXP,ISO)
diphenyl diselenide  (ISO)
disulfiram  (EXP)
dizocilpine maleate  (ISO)
donepezil hydrochloride  (ISO)
dopamine  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
echinacoside  (ISO)
elemental selenium  (ISO)
endosulfan  (ISO)
enzacamene  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
Ethylenethiourea  (EXP)
etoposide  (EXP)
eugenol  (ISO)
Evodiamine  (EXP)
excitatory amino acid agonist  (ISO)
Fast green FCF  (ISO)
fentanyl  (ISO)
fenvalerate  (ISO)
ferrostatin-1  (ISO)
fingolimod hydrochloride  (ISO)
fisetin  (ISO)
fluoranthene  (ISO)
fluoxetine  (EXP,ISO)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
fulvestrant  (EXP)
Fusaric acid  (ISO)
galactose  (ISO)
galangin  (ISO)
gallic acid  (EXP)
gallocatechin  (EXP)
gamma-aminobutyric acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
Gastrodin  (ISO)
gemcitabine  (EXP)
genistein  (ISO)
gentamycin  (ISO)
geraniol  (ISO)
gingerol  (ISO)
glycidol  (ISO)
glycyrrhizinic acid  (ISO)
glyphosate  (ISO)
haloperidol  (EXP,ISO)
herbicide  (ISO)
heroin  (EXP,ISO)
hydrogen peroxide  (EXP,ISO)
ifosfamide  (ISO)
imipramine  (ISO)
inulin  (ISO)
kainic acid  (ISO)
ketamine  (ISO)
ketanserin  (ISO)
KT 5823  (ISO)
L-ascorbic acid  (EXP,ISO)
L-methionine  (ISO)
lamotrigine  (ISO)
lead diacetate  (ISO)
lead(0)  (ISO)
linuron  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (EXP,ISO)
lithium chloride  (EXP)
lithium hydride  (EXP,ISO)
lovastatin  (ISO)
LY294002  (EXP,ISO)
lycopene  (ISO)
malathion  (EXP)
maneb  (ISO)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP,ISO)
melatonin  (ISO)
melittin  (ISO)
mercury atom  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (ISO)
mercury(0)  (EXP)
metformin  (ISO)
methamphetamine  (EXP,ISO)
methyl beta-cyclodextrin  (ISO)
methyl methanesulfonate  (EXP)
methylglyoxal  (EXP)
methyllycaconitine  (EXP)
methylmercury chloride  (EXP,ISO)
methylphenidate  (EXP,ISO)
mevastatin  (ISO)
mifepristone  (EXP,ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
morin  (ISO)
morphine  (ISO)
muscimol  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-methyl-N-nitrosourea  (ISO)
naproxen  (ISO)
nicardipine  (ISO)
nickel atom  (EXP)
nicotine  (EXP,ISO)
nicotinic acid  (ISO)
nifedipine  (ISO)
nimodipine  (ISO)
nitric oxide  (EXP)
Nonylphenol  (ISO)
ochratoxin A  (ISO)
olanzapine  (EXP,ISO)
oleuropein  (ISO)
ouabain  (ISO)
Oxadiazon  (EXP)
oxaliplatin  (ISO)
oxidopamine  (ISO)
ozone  (ISO)
paclitaxel  (ISO)
paliperidone palmitate  (ISO)
panaxydol  (ISO)
papaverine  (ISO)
paracetamol  (ISO)
paraldehyde  (ISO)
paraquat  (EXP,ISO)
parathion-methyl  (ISO)
paroxetine  (ISO)
pentetrazol  (ISO)
pentobarbital  (ISO)
perchlorate  (ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
permethrin  (EXP,ISO)
peroxynitrous acid  (ISO)
PF-3758309  (EXP)
phenobarbital  (ISO)
phenylephrine  (ISO)
phosphorothioic O,O,S-acid  (EXP)
picrotoxin  (ISO)
pioglitazone  (ISO)
poly(I:C)  (ISO)
potassium atom  (ISO)
potassium chloride  (ISO)
potassium chromate  (EXP)
prasugrel hydrochloride  (ISO)
prochloraz  (ISO)
procymidone  (ISO)
prodigiosin  (ISO)
progesterone  (EXP,ISO)
propanal  (EXP)
pyrethrins  (ISO)
Pyridostigmine bromide  (ISO)
pyrrolidine dithiocarbamate  (EXP)
quartz  (ISO)
quercetin  (ISO)
quetiapine fumarate  (ISO)
quinolinic acid  (ISO)
reserpine  (ISO)
resveratrol  (ISO)
rimonabant  (ISO)
risperidone  (EXP,ISO)
ritanserin  (ISO)
rivastigmine  (ISO)
roflumilast  (ISO)
rolipram  (ISO)
romidepsin  (ISO)
rotenone  (EXP,ISO)
royal jelly  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
salvianolic acid B  (ISO)
saroglitazar  (ISO)
saxagliptin  (ISO)
SB 431542  (EXP)
scopolamine  (ISO)
selenium atom  (ISO)
serotonin  (ISO)
sertraline  (ISO)
sevoflurane  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sirolimus  (ISO)
SKF-96365 hydrochloride  (ISO)
SL-327  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
Soman  (ISO)
sterigmatocystin  (ISO)
streptozocin  (ISO)
sulforaphane  (EXP)
sumatriptan  (ISO)
tacrine  (ISO)
tacrolimus hydrate  (ISO)
tadalafil  (ISO)
tamibarotene  (EXP,ISO)
tamoxifen  (EXP,ISO)
taurine  (EXP,ISO)
telmisartan  (ISO)
tert-butyl hydroperoxide  (EXP)
Testosterone propionate  (ISO)
tetrodotoxin  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
toluene  (ISO)
topiramate  (ISO)
torcetrapib  (EXP)
tranylcypromine  (ISO)
triacsin C  (EXP)
triazolam  (ISO)
triazophos  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
undecane  (ISO)
valproic acid  (EXP,ISO)
venlafaxine hydrochloride  (ISO)
veratridine  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
vortioxetine  (ISO)
VX nerve agent  (EXP,ISO)
wortmannin  (ISO)
xenon atom  (ISO)
xenon(0)  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc sulfate  (EXP,ISO)
zinc(0)  (ISO)
zolpidem  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
axon extension  (ISO)
axon guidance  (ISO,TAS)
axon target recognition  (ISO)
behavioral fear response  (ISO)
behavioral response to cocaine  (ISO)
brain-derived neurotrophic factor receptor signaling pathway  (TAS)
cell surface receptor protein tyrosine kinase signaling pathway  (IBA)
cellular response to nerve growth factor stimulus  (ISO)
cellular response to norepinephrine stimulus  (ISO)
cellular response to potassium ion  (ISO)
cellular response to tumor necrosis factor  (ISO)
chronic inflammatory response  (ISO)
circadian rhythm  (ISO)
cognition  (ISO)
collateral sprouting  (IDA)
conditioned place preference  (ISO)
dendrite development  (ISO)
dendrite extension  (ISO)
excitatory postsynaptic potential  (ISO)
fear response  (ISO)
feeding behavior  (ISO)
gamma-aminobutyric acid signaling pathway  (ISO)
glutamate secretion  (ISO)
inhibitory postsynaptic potential  (ISO)
inner ear development  (ISO)
learning  (ISO)
learning or memory  (ISO)
mechanoreceptor differentiation  (ISO)
mitochondrial electron transport, NADH to ubiquinone  (ISO)
modulation of chemical synaptic transmission  (IBA)
negative regulation of apoptotic process  (ISO)
negative regulation of apoptotic signaling pathway  (ISS)
negative regulation of myotube differentiation  (ISS)
negative regulation of neuroblast proliferation  (ISO)
negative regulation of neuron apoptotic process  (IBA,ISO)
negative regulation of programmed cell death  (ISO)
negative regulation of striated muscle tissue development  (ISO)
negative regulation of synaptic transmission, GABAergic  (ISO)
nerve development  (IBA,ISO)
nerve growth factor signaling pathway  (IBA)
nervous system development  (ISO,TAS)
neuron apoptotic process  (ISO)
neuron projection extension  (ISO)
neuron projection morphogenesis  (IBA)
neuron projection regeneration  (ISO)
neuron recognition  (ISO)
peptidyl-serine phosphorylation  (ISO)
positive regulation of axon extension  (ISO)
positive regulation of axon regeneration  (ISO)
positive regulation of brain-derived neurotrophic factor receptor signaling pathway  (TAS)
positive regulation of collateral sprouting  (IDA,ISO)
positive regulation of DNA-binding transcription factor activity  (ISO)
positive regulation of long-term neuronal synaptic plasticity  (ISO)
positive regulation of neuron apoptotic process  (ISO)
positive regulation of neuron differentiation  (ISO)
positive regulation of neuron projection development  (ISS)
positive regulation of nuclear receptor-mediated glucocorticoid signaling pathway  (ISO)
positive regulation of peptidyl-serine phosphorylation  (ISO)
positive regulation of synapse assembly  (IDA)
regeneration  (ISO)
regulation of axon extension  (ISO)
regulation of collateral sprouting  (ISO)
regulation of long-term neuronal synaptic plasticity  (ISO)
regulation of neuron apoptotic process  (ISO)
regulation of protein localization to cell surface  (TAS)
regulation of retinal cell programmed cell death  (ISO)
regulation of short-term neuronal synaptic plasticity  (ISO)
regulation of synaptic plasticity  (ISO)
response to activity  (ISO)
response to anesthetic  (ISO)
response to auditory stimulus  (ISO)
response to electrical stimulus  (ISO)
response to ethanol  (ISO)
response to food  (ISO)
response to hormone  (ISO)
response to hyperoxia  (ISO)
response to hypoxia  (ISO)
response to L-glutamate  (ISO)
response to light intensity  (ISO)
response to light stimulus  (ISO)
response to morphine  (ISO)
response to nerve growth factor  (ISO)
response to nutrient levels  (ISO)
response to potassium ion  (ISO)
response to tumor necrosis factor  (ISO)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)
synapse assembly  (IDA)
taste bud development  (ISO)
trans-synaptic signaling by BDNF, modulating synaptic transmission  (ISO)
ureteric bud development  (ISO)

Molecular Function

References

References - curated
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PMID:30387693   PMID:30388593   PMID:30402941   PMID:30418087   PMID:30428894   PMID:30448615   PMID:30448977   PMID:30449530   PMID:30456540   PMID:30472504   PMID:30519954   PMID:30522804  
PMID:30526722   PMID:30550003   PMID:30575024   PMID:30575339   PMID:30586536   PMID:30586546   PMID:30590963   PMID:30616127   PMID:30616482   PMID:30617785   PMID:30622436   PMID:30640051  
PMID:30641914   PMID:30644699   PMID:30659644   PMID:30664620   PMID:30670915   PMID:30674980   PMID:30677092   PMID:30695401   PMID:30710808   PMID:30711709   PMID:30771753   PMID:30775992  
PMID:30776391   PMID:30794585   PMID:30826210   PMID:30831210   PMID:30833610   PMID:30855519   PMID:30875771   PMID:30882674   PMID:30887472   PMID:30897622   PMID:30899092   PMID:30901514  
PMID:30904785   PMID:30909076   PMID:30909233   PMID:30952206   PMID:30965275   PMID:30967530   PMID:30981636   PMID:30988377   PMID:30991416   PMID:30992540   PMID:30994478   PMID:30998730  
PMID:31004714   PMID:31010680   PMID:31041673   PMID:31057094   PMID:31059136   PMID:31071716   PMID:31083054   PMID:31089096   PMID:31098654   PMID:31100426   PMID:31102717   PMID:31104169  
PMID:31112471   PMID:31132388   PMID:31134487   PMID:31172586   PMID:31180700   PMID:31197095   PMID:31202861   PMID:31208790   PMID:31210313   PMID:31234814   PMID:31247244   PMID:31255678  
PMID:31255912   PMID:31255950   PMID:31257632   PMID:31291217   PMID:31291230   PMID:31295515   PMID:31298409   PMID:31317694   PMID:31349032   PMID:31364951   PMID:31365694   PMID:31379269  
PMID:31420036   PMID:31425696   PMID:31437468   PMID:31445421   PMID:31453785   PMID:31464540   PMID:31465000   PMID:31487728   PMID:31495276   PMID:31502573   PMID:31524060   PMID:31541132  
PMID:31556385   PMID:31560105   PMID:31571628   PMID:31573330   PMID:31601338   PMID:31617281   PMID:31623079   PMID:31636250   PMID:31642812   PMID:31661631   PMID:31688181   PMID:31711978  
PMID:31713782   PMID:31736231   PMID:31746551   PMID:31756156   PMID:31760580   PMID:31767813   PMID:31771052   PMID:31820346   PMID:31839607   PMID:31845634   PMID:31900428   PMID:31910296  
PMID:31925827   PMID:31926908   PMID:31941116   PMID:31951637   PMID:32002751   PMID:32009534   PMID:32010924   PMID:32012942   PMID:32015336   PMID:32056765   PMID:32056943   PMID:32065946  
PMID:32066722   PMID:32075548   PMID:32077707   PMID:32079998   PMID:32080982   PMID:32081932   PMID:32085670   PMID:32085720   PMID:32122804   PMID:32124075   PMID:32157099   PMID:32171272  
PMID:32204647   PMID:32210348   PMID:32246495   PMID:32291635   PMID:32296183   PMID:32327658   PMID:32349267   PMID:32350920   PMID:32351633   PMID:32358323   PMID:32361384   PMID:32378476  
PMID:32390303   PMID:32397876   PMID:32416472   PMID:32423492   PMID:32428748   PMID:32482330   PMID:32492978   PMID:32562379   PMID:32565776   PMID:32570881   PMID:32573858   PMID:32605421  
PMID:32612070   PMID:32629065   PMID:32638952   PMID:32654287   PMID:32664008   PMID:32679912   PMID:32686489   PMID:32696315   PMID:32703621   PMID:32724091   PMID:32726665   PMID:32731218  
PMID:32736598   PMID:32759658   PMID:32798619   PMID:32804326   PMID:32808327   PMID:32810467   PMID:32813897   PMID:32814053   PMID:32815193   PMID:32819178   PMID:32848137   PMID:32859253  
PMID:32869548   PMID:32892314   PMID:32911446   PMID:32931807   PMID:32933711   PMID:32941187   PMID:32949664   PMID:32983417   PMID:32985495   PMID:32988741   PMID:32991522   PMID:32996114  
PMID:33002731   PMID:33004884   PMID:33007373   PMID:33015172   PMID:33029116   PMID:33036942   PMID:33044176   PMID:33047388   PMID:33047489   PMID:33050457   PMID:33053385   PMID:33060610  
PMID:33063528   PMID:33068389   PMID:33073590   PMID:33077716   PMID:33087740   PMID:33096634   PMID:33105359   PMID:33160139   PMID:33173426   PMID:33179143   PMID:33182716   PMID:33215284  
PMID:33215785   PMID:33222311   PMID:33222669   PMID:33253827   PMID:33271690   PMID:33288548   PMID:33302387   PMID:33306590   PMID:33306691   PMID:33315318   PMID:33324399   PMID:33325388  
PMID:33338736   PMID:33340609   PMID:33358916   PMID:33358963   PMID:33360223   PMID:33369083   PMID:33370585   PMID:33389140   PMID:33389158   PMID:33405375   PMID:33413076   PMID:33434621  
PMID:33441099   PMID:33444650   PMID:33450468   PMID:33477654   PMID:33479229   PMID:33485990   PMID:33499851   PMID:33523719   PMID:33561695   PMID:33568689   PMID:33574220   PMID:33578508  
PMID:33603039   PMID:33605167   PMID:33628340   PMID:33637225   PMID:33660804   PMID:33662047   PMID:33666096   PMID:33721459   PMID:33749030   PMID:33753004   PMID:33757426   PMID:33762638  
PMID:33773278   PMID:33773809   PMID:33787399   PMID:33798614   PMID:33812160   PMID:33835731   PMID:33857523   PMID:33862146   PMID:33876571   PMID:33878808   PMID:33883635   PMID:33910384  
PMID:33926045   PMID:33930460   PMID:33942699   PMID:33957818   PMID:33961781   PMID:33971247   PMID:33985854   PMID:33993081   PMID:34000980   PMID:34008409   PMID:34053675   PMID:34160912  
PMID:34173192   PMID:34175359   PMID:34176754   PMID:34209215   PMID:34209365   PMID:34215825   PMID:34245319   PMID:34248009   PMID:34256395   PMID:34258927   PMID:34263656   PMID:34263997  
PMID:34267235   PMID:34281873   PMID:34321412   PMID:34340176   PMID:34341419   PMID:34346275   PMID:34359010   PMID:34367374   PMID:34415897   PMID:34418703   PMID:34418778   PMID:34425486  
PMID:34445512   PMID:34467592   PMID:34478125   PMID:34518555   PMID:34525971   PMID:34528295   PMID:34533795   PMID:34536433   PMID:34537904   PMID:34546355   PMID:34573321   PMID:34580389  
PMID:34591410   PMID:34592560   PMID:34601245   PMID:34602450   PMID:34610834   PMID:34625629   PMID:34637871   PMID:34650209   PMID:34653830   PMID:34653961   PMID:34654737   PMID:34750906  
PMID:34757248   PMID:34760029   PMID:34763683   PMID:34788141   PMID:34856753   PMID:34879183   PMID:34896179   PMID:34936818   PMID:34954335   PMID:34965503   PMID:34974714   PMID:34989854  
PMID:34990638   PMID:34991456   PMID:34997117   PMID:35009001   PMID:35023483   PMID:35077325   PMID:35099506   PMID:35121746   PMID:35128618   PMID:35129860   PMID:35152066   PMID:35165396  
PMID:35205376   PMID:35206257   PMID:35208502   PMID:35219096   PMID:35228136   PMID:35292247   PMID:35295960   PMID:35300713   PMID:35314247   PMID:35328036   PMID:35349796   PMID:35354697  
PMID:35364229   PMID:35378105   PMID:35451419   PMID:35453068   PMID:35459929   PMID:35465864   PMID:35486119   PMID:35489561   PMID:35508633   PMID:35599479   PMID:35605794   PMID:35633348  
PMID:35662115   PMID:35666604   PMID:35679772   PMID:35696571   PMID:35717586   PMID:35718045   PMID:35718064   PMID:35728773   PMID:35743044   PMID:35748555   PMID:35749045   PMID:35809326  
PMID:35866837   PMID:35886019   PMID:35887357   PMID:35905107   PMID:35905264   PMID:35905690   PMID:35918221   PMID:35927806   PMID:35947418   PMID:35962006   PMID:35970042   PMID:35988269  
PMID:35998179   PMID:36108429   PMID:36114161   PMID:36115874   PMID:36168703   PMID:36173064   PMID:36181754   PMID:36214902   PMID:36223549   PMID:36268760   PMID:36329115   PMID:36336706  
PMID:36355087   PMID:36367618   PMID:36394751   PMID:36398374   PMID:36411369   PMID:36438922   PMID:36441149   PMID:36453692   PMID:36481244   PMID:36498925   PMID:36510348   PMID:36528281  
PMID:36550387   PMID:36563920   PMID:36567420   PMID:36577338   PMID:36597258   PMID:36621163   PMID:36630045   PMID:36681359   PMID:36682419   PMID:36719088   PMID:36737401   PMID:36739005  
PMID:36764636   PMID:36766691   PMID:36780947   PMID:36787304   PMID:36794980   PMID:36800691   PMID:36834953   PMID:36835126   PMID:36855816   PMID:36884028   PMID:36898188   PMID:36950384  
PMID:36970903   PMID:36977737   PMID:36999446   PMID:37019247   PMID:37038358   PMID:37072879   PMID:37075935   PMID:37076286   PMID:37085692   PMID:37094390   PMID:37146499   PMID:37150680  
PMID:37175781   PMID:37182424   PMID:37186275   PMID:37220696   PMID:37230202   PMID:37252844   PMID:37257214   PMID:37315256   PMID:37334438   PMID:37334527   PMID:37334646   PMID:37335428  
PMID:37358362   PMID:37387382   PMID:37404130   PMID:37460933   PMID:37462904   PMID:37491857   PMID:37508514   PMID:37520481   PMID:37522679   PMID:37548699   PMID:37596403   PMID:37675625  
PMID:37692110   PMID:37703265   PMID:37706246   PMID:37759825   PMID:37770565   PMID:37820958   PMID:37865417   PMID:37871642   PMID:37944291   PMID:38006577   PMID:38008209   PMID:38009531  
PMID:38063117   PMID:38070471   PMID:38110605   PMID:38114721   PMID:38127937   PMID:38136952   PMID:38142902   PMID:38148427   PMID:38151886   PMID:38164567   PMID:38218833   PMID:38228888  
PMID:38243072   PMID:38245698   PMID:38254671   PMID:38255861   PMID:38261293   PMID:38279143   PMID:38331308   PMID:38338875   PMID:38379321   PMID:38385466   PMID:38397427   PMID:38417539  
PMID:38447916   PMID:38454193   PMID:38503023   PMID:38542252   PMID:38554393   PMID:38564888   PMID:38677095   PMID:38706964   PMID:38720004   PMID:38726479   PMID:38749085   PMID:38788070  
PMID:38791290   PMID:38861537   PMID:38982490   PMID:38988190   PMID:39334009   PMID:39392027  


Genomics

Comparative Map Data
BDNF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381127,654,893 - 27,722,030 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1127,654,893 - 27,722,058 (-)Ensemblhg38GRCh38
GRCh371127,676,440 - 27,743,577 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361127,633,016 - 27,699,872 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341127,633,019 - 27,637,249NCBI
Celera1127,822,548 - 27,889,725 (-)NCBICelera
Cytogenetic Map11p14.1NCBI
HuRef1127,374,586 - 27,441,772 (-)NCBIHuRef
CHM1_11127,675,184 - 27,742,527 (-)NCBICHM1_1
T2T-CHM13v2.01127,795,301 - 27,862,460 (-)NCBIT2T-CHM13v2.0
Bdnf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392109,505,045 - 109,557,388 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2109,505,045 - 109,557,352 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382109,674,700 - 109,727,043 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2109,674,700 - 109,727,007 (+)Ensemblmm10GRCm38
MGSCv372109,514,857 - 109,567,200 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362109,475,539 - 109,527,845 (+)NCBIMGSCv36mm8
Celera2110,835,441 - 110,887,723 (+)NCBICelera
Cytogenetic Map2E3NCBI
cM Map256.63NCBI
Bdnf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83116,619,633 - 116,670,212 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3116,619,633 - 116,670,657 (+)EnsemblGRCr8
mRatBN7.2396,165,042 - 96,215,621 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl396,165,042 - 96,215,615 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx399,726,226 - 99,776,801 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03108,325,184 - 108,375,759 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03106,087,694 - 106,138,272 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03100,768,637 - 100,819,216 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3100,768,637 - 100,819,210 (+)Ensemblrn6Rnor6.0
Rnor_5.03107,371,329 - 107,421,908 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera395,191,318 - 95,241,949 (+)NCBICelera
Cytogenetic Map3q34NCBI
Bdnf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554766,772,088 - 6,822,588 (-)Ensembl
ChiLan1.0NW_0049554766,773,244 - 6,822,201 (-)NCBIChiLan1.0ChiLan1.0
BDNF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2929,867,082 - 29,934,015 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11129,867,593 - 29,934,527 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01127,618,322 - 27,687,661 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11127,520,306 - 27,589,239 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1127,520,312 - 27,589,239 (-)EnsemblpanPan2panpan1.1
BDNF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12148,191,580 - 48,243,699 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2148,192,670 - 48,204,480 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2147,689,871 - 47,691,000 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02149,335,793 - 49,386,964 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.12148,338,131 - 48,339,260 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02148,489,388 - 48,490,517 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02149,083,467 - 49,084,596 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Bdnf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494736,374,992 - 36,427,979 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365405,529,942 - 5,585,014 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365405,530,081 - 5,582,765 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BDNF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl232,624,048 - 32,679,765 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1232,623,668 - 32,679,293 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2235,206,996 - 35,265,002 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BDNF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1137,386,825 - 37,451,380 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl137,449,593 - 37,450,336 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038134,690,869 - 134,762,531 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Bdnf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476617,279,630 - 17,330,490 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476617,281,882 - 17,330,601 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in BDNF
154 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001709.5(BDNF):c.-46C>T single nucleotide variant Variant of unknown significance [RCV000019273] Chr11:27700188 [GRCh38]
Chr11:27721735 [GRCh37]
Chr11:11p14.1
pathogenic|uncertain significance
NM_001709.5(BDNF):c.5C>T (p.Thr2Ile) single nucleotide variant BDNF-related disorder [RCV003914855]|Congenital central hypoventilation [RCV000019266]|Obesity [RCV000988510]|not provided [RCV002513118]|not specified [RCV000790920] Chr11:27658560 [GRCh38]
Chr11:27680107 [GRCh37]
Chr11:11p14.1
pathogenic|likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_001709.5(BDNF):c.196G>A (p.Val66Met) single nucleotide variant Memory impairment, susceptibility to [RCV000019267]|not provided [RCV002054446]|not specified [RCV000155463] Chr11:27658369 [GRCh38]
Chr11:27679916 [GRCh37]
Chr11:11p14.1
risk factor|association|benign|protective|not provided
GRCh38/hg38 11p14.3-12(chr11:22550115-38199159)x1 copy number loss See cases [RCV000052648] Chr11:22550115..38199159 [GRCh38]
Chr11:22571661..38220709 [GRCh37]
Chr11:22528237..38177285 [NCBI36]
Chr11:11p14.3-12
pathogenic
GRCh38/hg38 11p15.5-13(chr11:202758-31726224)x3 copy number gain See cases [RCV000053613] Chr11:202758..31726224 [GRCh38]
Chr11:202758..31747772 [GRCh37]
Chr11:192758..31704348 [NCBI36]
Chr11:11p15.5-13
pathogenic
NM_170731.4(BDNF):c.103C>T (p.Arg35Ter) single nucleotide variant Malignant melanoma [RCV000069311] Chr11:27658486 [GRCh38]
Chr11:27680033 [GRCh37]
Chr11:27636609 [NCBI36]
Chr11:11p14.1
not provided
GRCh38/hg38 11p14.2-13(chr11:26368962-35252976)x1 copy number loss See cases [RCV000135295] Chr11:26368962..35252976 [GRCh38]
Chr11:26390509..35274523 [GRCh37]
Chr11:26347085..35231099 [NCBI36]
Chr11:11p14.2-13
pathogenic
GRCh38/hg38 11p14.3-13(chr11:24595399-31096539)x3 copy number gain See cases [RCV000134877] Chr11:24595399..31096539 [GRCh38]
Chr11:24616945..31118086 [GRCh37]
Chr11:24573521..31074662 [NCBI36]
Chr11:11p14.3-13
pathogenic
GRCh38/hg38 11p14.3-14.1(chr11:23024064-27978597)x1 copy number loss See cases [RCV000137723] Chr11:23024064..27978597 [GRCh38]
Chr11:23045610..28000144 [GRCh37]
Chr11:23002186..27956720 [NCBI36]
Chr11:11p14.3-14.1
likely pathogenic
GRCh38/hg38 11p15.1-13(chr11:20079474-34463996)x1 copy number loss See cases [RCV000142499] Chr11:20079474..34463996 [GRCh38]
Chr11:20101020..34485543 [GRCh37]
Chr11:20057596..34442119 [NCBI36]
Chr11:11p15.1-13
pathogenic
NM_001709.5(BDNF):c.-22+774G>A single nucleotide variant not provided [RCV004718045]|not specified [RCV000150189] Chr11:27699390 [GRCh38]
Chr11:27720937 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.450= (p.Ala150=) single nucleotide variant not provided [RCV002056111]|not specified [RCV000156118] Chr11:27658115 [GRCh38]
Chr11:27679662 [GRCh37]
Chr11:11p14.1
benign
GRCh37/hg19 11p14.1(chr11:27407012-28000144)x3 copy number gain See cases [RCV000240429] Chr11:27407012..28000144 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.502G>T (p.Glu168Ter) single nucleotide variant Inborn genetic diseases [RCV000622995] Chr11:27658063 [GRCh38]
Chr11:27679610 [GRCh37]
Chr11:11p14.1
likely pathogenic
NM_001709.5(BDNF):c.-21-15685_-21-15684del deletion not specified [RCV000595956] Chr11:27674269..27674270 [GRCh38]
Chr11:27695816..27695817 [GRCh37]
Chr11:11p14.1
uncertain significance
GRCh37/hg19 11p15.1-13(chr11:18536224-31923308)x1 copy number loss Aniridia 1 [RCV000420782] Chr11:18536224..31923308 [GRCh37]
Chr11:11p15.1-13
pathogenic
GRCh37/hg19 11p15.1-13(chr11:21586131-33168232)x1 copy number loss Wilms tumor, aniridia, genitourinary anomalies, intellectual disability, and obesity syndrome [RCV000435400] Chr11:21586131..33168232 [GRCh37]
Chr11:11p15.1-13
pathogenic
GRCh37/hg19 11p14.2-11.12(chr11:26574629-50508019)x3 copy number gain See cases [RCV000448603] Chr11:26574629..50508019 [GRCh37]
Chr11:11p14.2-11.12
pathogenic
GRCh37/hg19 11p14.3-13(chr11:25771208-35614978)x1 copy number loss See cases [RCV000512014] Chr11:25771208..35614978 [GRCh37]
Chr11:11p14.3-13
pathogenic
GRCh37/hg19 11p15.5-12(chr11:230615-37698540)x3 copy number gain See cases [RCV000511561] Chr11:230615..37698540 [GRCh37]
Chr11:11p15.5-12
pathogenic
GRCh37/hg19 11p14.1-12(chr11:27588560-41770792)x1 copy number loss See cases [RCV000511434] Chr11:27588560..41770792 [GRCh37]
Chr11:11p14.1-12
pathogenic|uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_001709.5(BDNF):c.-22+764G>C single nucleotide variant not specified [RCV000601884] Chr11:27699400 [GRCh38]
Chr11:27720947 [GRCh37]
Chr11:11p14.1
uncertain significance
GRCh37/hg19 11p15.5-13(chr11:230615-31995219)x3 copy number gain See cases [RCV000512477] Chr11:230615..31995219 [GRCh37]
Chr11:11p15.5-13
pathogenic
GRCh37/hg19 11p14.3-14.1(chr11:25090108-28909131)x3 copy number gain not provided [RCV000683363] Chr11:25090108..28909131 [GRCh37]
Chr11:11p14.3-14.1
uncertain significance
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p14.3-12(chr11:24469451-37524085)x1 copy number loss not provided [RCV000737457] Chr11:24469451..37524085 [GRCh37]
Chr11:11p14.3-12
pathogenic
GRCh37/hg19 11p14.3-13(chr11:25196998-34196484)x1 copy number loss not provided [RCV000737466] Chr11:25196998..34196484 [GRCh37]
Chr11:11p14.3-13
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p14.2-13(chr11:27154853-33302474)x1 copy number loss not provided [RCV000749997] Chr11:27154853..33302474 [GRCh37]
Chr11:11p14.2-13
pathogenic
NM_001709.5(BDNF):c.483C>A (p.Gly161=) single nucleotide variant not provided [RCV000976679] Chr11:27658082 [GRCh38]
Chr11:27679629 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15633G>A single nucleotide variant Obesity [RCV000754971] Chr11:27674218 [GRCh38]
Chr11:27695765 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.546C>T (p.Tyr182=) single nucleotide variant BDNF-related disorder [RCV003940507]|not provided [RCV000884732] Chr11:27658019 [GRCh38]
Chr11:27679566 [GRCh37]
Chr11:11p14.1
benign|likely benign
NM_001709.5(BDNF):c.642C>T (p.Tyr214=) single nucleotide variant not provided [RCV000951291] Chr11:27657923 [GRCh38]
Chr11:27679470 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.417C>T (p.Ser139=) single nucleotide variant BDNF-related disorder [RCV004746124]|not provided [RCV000881363] Chr11:27658148 [GRCh38]
Chr11:27679695 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.450G>A (p.Ala150=) single nucleotide variant not provided [RCV000964612]|not specified [RCV004017766] Chr11:27658115 [GRCh38]
Chr11:27679662 [GRCh37]
Chr11:11p14.1
benign
GRCh37/hg19 11p15.3-13(chr11:11053978-34732891)x3 copy number gain not provided [RCV001006387] Chr11:11053978..34732891 [GRCh37]
Chr11:11p15.3-13
pathogenic
NM_001709.5(BDNF):c.639G>A (p.Ser213=) single nucleotide variant not provided [RCV000891648] Chr11:27657926 [GRCh38]
Chr11:27679473 [GRCh37]
Chr11:11p14.1
benign
GRCh37/hg19 11p14.3-13(chr11:22079154-35597645)x1 copy number loss not provided [RCV000849589] Chr11:22079154..35597645 [GRCh37]
Chr11:11p14.3-13
pathogenic
NM_001709.5(BDNF):c.136G>A (p.Val46Met) single nucleotide variant BDNF-related disorder [RCV003393061]|not provided [RCV003778321] Chr11:27658429 [GRCh38]
Chr11:27679976 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15653T>C single nucleotide variant not specified [RCV001699686] Chr11:27674238 [GRCh38]
Chr11:27695785 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-15332T>C single nucleotide variant not provided [RCV001639767] Chr11:27673917 [GRCh38]
Chr11:27695464 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.483C>T (p.Gly161=) single nucleotide variant BDNF-related disorder [RCV003902990]|not provided [RCV000920255] Chr11:27658082 [GRCh38]
Chr11:27679629 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.321C>G (p.Leu107=) single nucleotide variant not provided [RCV000911836] Chr11:27658244 [GRCh38]
Chr11:27679791 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-15601_-21-15600del deletion BDNF-related disorder [RCV003401662]|not provided [RCV001730262] Chr11:27674185..27674186 [GRCh38]
Chr11:27695732..27695733 [GRCh37]
Chr11:11p14.1
likely benign|uncertain significance
GRCh37/hg19 11p15.5-13(chr11:235934-33826995)x3 copy number gain not provided [RCV001006372] Chr11:235934..33826995 [GRCh37]
Chr11:11p15.5-13
pathogenic
NM_001709.5(BDNF):c.-21-1064CA[11] microsatellite not provided [RCV001669309] Chr11:27659629..27659630 [GRCh38]
Chr11:27681176..27681177 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-1044G>C single nucleotide variant not provided [RCV001669145] Chr11:27659629 [GRCh38]
Chr11:27681176 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.557G>A (p.Cys186Tyr) single nucleotide variant Obesity [RCV001261409] Chr11:27658008 [GRCh38]
Chr11:27679555 [GRCh37]
Chr11:11p14.1
likely pathogenic
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
NM_001143808.2(BDNF):c.-22+2T>G single nucleotide variant BDNF-related disorder [RCV003928861]|not provided [RCV001357477] Chr11:27700979 [GRCh38]
Chr11:27722526 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-1256G>A single nucleotide variant not provided [RCV001708958] Chr11:27659841 [GRCh38]
Chr11:27681388 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-1064CA[13] microsatellite not provided [RCV001615493] Chr11:27659629..27659630 [GRCh38]
Chr11:27681176..27681177 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-15778G>T single nucleotide variant not provided [RCV001687535] Chr11:27674363 [GRCh38]
Chr11:27695910 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-15304= single nucleotide variant not provided [RCV001711020] Chr11:27673889 [GRCh38]
Chr11:27695436 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.-21-1065G>A single nucleotide variant not provided [RCV001708763] Chr11:27659650 [GRCh38]
Chr11:27681197 [GRCh37]
Chr11:11p14.1
benign
NM_001709.5(BDNF):c.643G>A (p.Val215Met) single nucleotide variant not provided [RCV001726839] Chr11:27657922 [GRCh38]
Chr11:27679469 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.542T>G (p.Phe181Cys) single nucleotide variant Inherited obesity [RCV004818543] Chr11:27658023 [GRCh38]
Chr11:27679570 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.273G>A (p.Thr91=) single nucleotide variant BDNF-related disorder [RCV003913612]|not provided [RCV002219957] Chr11:27658292 [GRCh38]
Chr11:27679839 [GRCh37]
Chr11:11p14.1
likely benign
GRCh37/hg19 11p14.1-13(chr11:27547893-31656604)x1 copy number loss not provided [RCV002265529] Chr11:27547893..31656604 [GRCh37]
Chr11:11p14.1-13
not provided
GRCh37/hg19 11p14.1(chr11:27382897-29172035)x1 copy number loss See cases [RCV002292391] Chr11:27382897..29172035 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.170C>A (p.Thr57Lys) single nucleotide variant Inborn genetic diseases [RCV002840034] Chr11:27658395 [GRCh38]
Chr11:27679942 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.128T>C (p.Leu43Pro) single nucleotide variant Inborn genetic diseases [RCV002839678] Chr11:27658437 [GRCh38]
Chr11:27679984 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.366G>T (p.Met122Ile) single nucleotide variant not provided [RCV002815720] Chr11:27658199 [GRCh38]
Chr11:27679746 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.70G>A (p.Ala24Thr) single nucleotide variant Inborn genetic diseases [RCV002836785] Chr11:27658495 [GRCh38]
Chr11:27680042 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.609T>C (p.His203=) single nucleotide variant not provided [RCV002928085] Chr11:27657956 [GRCh38]
Chr11:27679503 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.233G>A (p.Arg78Gln) single nucleotide variant BDNF-related disorder [RCV004747243]|Inborn genetic diseases [RCV002798325] Chr11:27658332 [GRCh38]
Chr11:27679879 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.447G>A (p.Thr149=) single nucleotide variant BDNF-related disorder [RCV003928910]|Inborn genetic diseases [RCV002887297]|not provided [RCV003738324] Chr11:27658118 [GRCh38]
Chr11:27679665 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.164G>T (p.Gly55Val) single nucleotide variant Inborn genetic diseases [RCV002782083] Chr11:27658401 [GRCh38]
Chr11:27679948 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.323T>A (p.Phe108Tyr) single nucleotide variant not provided [RCV002735121] Chr11:27658242 [GRCh38]
Chr11:27679789 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.223C>G (p.Gln75Glu) single nucleotide variant BDNF-related disorder [RCV003420539]|Inborn genetic diseases [RCV002805148] Chr11:27658342 [GRCh38]
Chr11:27679889 [GRCh37]
Chr11:11p14.1
likely benign|uncertain significance
NM_001709.5(BDNF):c.184A>G (p.Thr62Ala) single nucleotide variant Inborn genetic diseases [RCV002831186] Chr11:27658381 [GRCh38]
Chr11:27679928 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.49A>G (p.Lys17Glu) single nucleotide variant not provided [RCV003008479] Chr11:27658516 [GRCh38]
Chr11:27680063 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001143809.2(BDNF):c.49G>A (p.Ala17Thr) single nucleotide variant BDNF-related disorder [RCV003419127] Chr11:27700988 [GRCh38]
Chr11:27722535 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15487T>G single nucleotide variant BDNF-related disorder [RCV003419162] Chr11:27674072 [GRCh38]
Chr11:27695619 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.365T>C (p.Met122Thr) single nucleotide variant BDNF-related disorder [RCV003412001] Chr11:27658200 [GRCh38]
Chr11:27679747 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15496C>G single nucleotide variant BDNF-related disorder [RCV003392770] Chr11:27674081 [GRCh38]
Chr11:27695628 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.5C>A (p.Thr2Asn) single nucleotide variant BDNF-related disorder [RCV003404640] Chr11:27658560 [GRCh38]
Chr11:27680107 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15533T>C single nucleotide variant BDNF-related disorder [RCV003391508] Chr11:27674118 [GRCh38]
Chr11:27695665 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.92G>A (p.Gly31Asp) single nucleotide variant BDNF-related disorder [RCV003408713] Chr11:27658473 [GRCh38]
Chr11:27680020 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.659T>C (p.Met220Thr) single nucleotide variant BDNF-related disorder [RCV003412440] Chr11:27657906 [GRCh38]
Chr11:27679453 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15481C>A single nucleotide variant BDNF-related disorder [RCV003405951] Chr11:27674066 [GRCh38]
Chr11:27695613 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.226A>G (p.Lys76Glu) single nucleotide variant BDNF-related disorder [RCV003399548] Chr11:27658339 [GRCh38]
Chr11:27679886 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15659_-21-15656dup duplication BDNF-related disorder [RCV003417130] Chr11:27674240..27674241 [GRCh38]
Chr11:27695787..27695788 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.691A>G (p.Ile231Val) single nucleotide variant BDNF-related disorder [RCV003410856] Chr11:27657874 [GRCh38]
Chr11:27679421 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.113G>A (p.Arg38Gln) single nucleotide variant BDNF-related disorder [RCV003417144] Chr11:27658452 [GRCh38]
Chr11:27679999 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.72A>G (p.Ala24=) single nucleotide variant not provided [RCV003692609] Chr11:27658493 [GRCh38]
Chr11:27680040 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.172T>C (p.Ser58Pro) single nucleotide variant not provided [RCV003822313] Chr11:27658393 [GRCh38]
Chr11:27679940 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.610del (p.Trp204fs) deletion not provided [RCV003719409] Chr11:27657955 [GRCh38]
Chr11:27679502 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.258C>T (p.Asp86=) single nucleotide variant BDNF-related disorder [RCV003939123]|Inborn genetic diseases [RCV005301319]|not provided [RCV003564868] Chr11:27658307 [GRCh38]
Chr11:27679854 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.135C>T (p.Ser45=) single nucleotide variant BDNF-related disorder [RCV003977379] Chr11:27658430 [GRCh38]
Chr11:27679977 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.102C>T (p.Tyr34=) single nucleotide variant BDNF-related disorder [RCV003894003] Chr11:27658463 [GRCh38]
Chr11:27680010 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.239A>G (p.Asn80Ser) single nucleotide variant BDNF-related disorder [RCV003979549] Chr11:27658326 [GRCh38]
Chr11:27679873 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001143809.2(BDNF):c.39G>C (p.Lys13Asn) single nucleotide variant BDNF-related disorder [RCV003956950] Chr11:27700998 [GRCh38]
Chr11:27722545 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.195C>T (p.His65=) single nucleotide variant BDNF-related disorder [RCV003981835] Chr11:27658370 [GRCh38]
Chr11:27679917 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.154G>A (p.Gly52Ser) single nucleotide variant BDNF-related disorder [RCV003957003] Chr11:27658411 [GRCh38]
Chr11:27679958 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15592C>T single nucleotide variant BDNF-related disorder [RCV003899378] Chr11:27674177 [GRCh38]
Chr11:27695724 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15571A>G single nucleotide variant BDNF-related disorder [RCV003951854] Chr11:27674156 [GRCh38]
Chr11:27695703 [GRCh37]
Chr11:11p14.1
likely benign
NM_001143809.2(BDNF):c.66+8T>C single nucleotide variant BDNF-related disorder [RCV003941878] Chr11:27700963 [GRCh38]
Chr11:27722510 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15601A>G single nucleotide variant BDNF-related disorder [RCV003907203] Chr11:27674186 [GRCh38]
Chr11:27695733 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.309G>A (p.Glu103=) single nucleotide variant BDNF-related disorder [RCV003934389] Chr11:27658256 [GRCh38]
Chr11:27679803 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.480G>A (p.Ser160=) single nucleotide variant BDNF-related disorder [RCV003924661] Chr11:27658085 [GRCh38]
Chr11:27679632 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15610G>A single nucleotide variant BDNF-related disorder [RCV003943953] Chr11:27674195 [GRCh38]
Chr11:27695742 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.465T>C (p.Thr155=) single nucleotide variant BDNF-related disorder [RCV003901373] Chr11:27658100 [GRCh38]
Chr11:27679647 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.241G>T (p.Glu81Ter) single nucleotide variant not provided [RCV004575952] Chr11:27658324 [GRCh38]
Chr11:27679871 [GRCh37]
Chr11:11p14.1
uncertain significance
NC_000011.9:g.(?_27528379)_(27744859_?)del deletion not provided [RCV004580377] Chr11:27528379..27744859 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.101A>G (p.Tyr34Cys) single nucleotide variant Inborn genetic diseases [RCV004600128] Chr11:27658464 [GRCh38]
Chr11:27680011 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_170731.5(BDNF):c.3+20368T>C single nucleotide variant BDNF-related disorder [RCV004745785] Chr11:27701044 [GRCh38]
Chr11:27722591 [GRCh37]
Chr11:11p14.1
likely benign
NM_001143809.2(BDNF):c.28C>T (p.Arg10Cys) single nucleotide variant BDNF-related disorder [RCV004745869] Chr11:27701009 [GRCh38]
Chr11:27722556 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.630T>C (p.Thr210=) single nucleotide variant BDNF-related disorder [RCV004746059] Chr11:27657935 [GRCh38]
Chr11:27679482 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15688C>T single nucleotide variant BDNF-related disorder [RCV004746789] Chr11:27674273 [GRCh38]
Chr11:27695820 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.226A>C (p.Lys76Gln) single nucleotide variant BDNF-related disorder [RCV004726510] Chr11:27658339 [GRCh38]
Chr11:27679886 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15591G>A single nucleotide variant BDNF-related disorder [RCV004746635] Chr11:27674176 [GRCh38]
Chr11:27695723 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15634T>C single nucleotide variant BDNF-related disorder [RCV004746688] Chr11:27674219 [GRCh38]
Chr11:27695766 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15529C>T single nucleotide variant BDNF-related disorder [RCV004747594] Chr11:27674114 [GRCh38]
Chr11:27695661 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.466G>A (p.Ala156Thr) single nucleotide variant BDNF-related disorder [RCV004726654] Chr11:27658099 [GRCh38]
Chr11:27679646 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.15C>T (p.Phe5=) single nucleotide variant BDNF-related disorder [RCV004747884] Chr11:27658550 [GRCh38]
Chr11:27680097 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.508G>A (p.Val170Ile) single nucleotide variant BDNF-related disorder [RCV004746708] Chr11:27658057 [GRCh38]
Chr11:27679604 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.*9T>C single nucleotide variant BDNF-related disorder [RCV004746825] Chr11:27657812 [GRCh38]
Chr11:27679359 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.463A>T (p.Thr155Ser) single nucleotide variant BDNF-related disorder [RCV004747003] Chr11:27658102 [GRCh38]
Chr11:27679649 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001143809.2(BDNF):c.63G>A (p.Gly21=) single nucleotide variant BDNF-related disorder [RCV004747955] Chr11:27700974 [GRCh38]
Chr11:27722521 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15623A>C single nucleotide variant BDNF-related disorder [RCV004747583] Chr11:27674208 [GRCh38]
Chr11:27695755 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001143809.2(BDNF):c.53G>A (p.Gly18Glu) single nucleotide variant BDNF-related disorder [RCV004748000] Chr11:27700984 [GRCh38]
Chr11:27722531 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15523C>T single nucleotide variant BDNF-related disorder [RCV004745736] Chr11:27674108 [GRCh38]
Chr11:27695655 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.735G>A (p.Arg245=) single nucleotide variant BDNF-related disorder [RCV004745715] Chr11:27657830 [GRCh38]
Chr11:27679377 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.111G>A (p.Val37=) single nucleotide variant BDNF-related disorder [RCV004745765] Chr11:27658454 [GRCh38]
Chr11:27680001 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.190G>A (p.Glu64Lys) single nucleotide variant BDNF-related disorder [RCV004745959] Chr11:27658375 [GRCh38]
Chr11:27679922 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15556A>G single nucleotide variant BDNF-related disorder [RCV004747581] Chr11:27674141 [GRCh38]
Chr11:27695688 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.563C>G (p.Pro188Arg) single nucleotide variant BDNF-related disorder [RCV004747611] Chr11:27658002 [GRCh38]
Chr11:27679549 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.360A>G (p.Ala120=) single nucleotide variant BDNF-related disorder [RCV004747766] Chr11:27658205 [GRCh38]
Chr11:27679752 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.633C>A (p.Thr211=) single nucleotide variant BDNF-related disorder [RCV004729963] Chr11:27657932 [GRCh38]
Chr11:27679479 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.495A>T (p.Thr165=) single nucleotide variant BDNF-related disorder [RCV004747993] Chr11:27658070 [GRCh38]
Chr11:27679617 [GRCh37]
Chr11:11p14.1
likely benign
NM_001143809.2(BDNF):c.2T>C (p.Met1Thr) single nucleotide variant BDNF-related disorder [RCV004747848] Chr11:27701035 [GRCh38]
Chr11:27722582 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.715T>G (p.Cys239Gly) single nucleotide variant BDNF-related disorder [RCV004729666] Chr11:27657850 [GRCh38]
Chr11:27679397 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.81A>C (p.Arg27=) single nucleotide variant BDNF-related disorder [RCV004745677] Chr11:27658484 [GRCh38]
Chr11:27680031 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.*4A>G single nucleotide variant BDNF-related disorder [RCV004745704] Chr11:27657817 [GRCh38]
Chr11:27679364 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.534G>A (p.Lys178=) single nucleotide variant BDNF-related disorder [RCV004745730] Chr11:27658031 [GRCh38]
Chr11:27679578 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.721T>C (p.Leu241=) single nucleotide variant BDNF-related disorder [RCV004746111] Chr11:27657844 [GRCh38]
Chr11:27679391 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.114G>T (p.Arg38=) single nucleotide variant BDNF-related disorder [RCV004746992] Chr11:27658451 [GRCh38]
Chr11:27679998 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.280G>A (p.Val94Met) single nucleotide variant BDNF-related disorder [RCV004747783] Chr11:27658285 [GRCh38]
Chr11:27679832 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15625A>G single nucleotide variant BDNF-related disorder [RCV004724278] Chr11:27674210 [GRCh38]
Chr11:27695757 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.638C>T (p.Ser213Leu) single nucleotide variant BDNF-related disorder [RCV004746101] Chr11:27657927 [GRCh38]
Chr11:27679474 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.36C>A (p.Tyr12Ter) single nucleotide variant BDNF-related disorder [RCV004746707] Chr11:27658529 [GRCh38]
Chr11:27680076 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_170731.5(BDNF):c.3+20367A>G single nucleotide variant BDNF-related disorder [RCV004746685] Chr11:27701045 [GRCh38]
Chr11:27722592 [GRCh37]
Chr11:11p14.1
likely benign
NM_001143809.2(BDNF):c.39G>A (p.Lys13=) single nucleotide variant BDNF-related disorder [RCV004747787] Chr11:27700998 [GRCh38]
Chr11:27722545 [GRCh37]
Chr11:11p14.1
likely benign
NM_001143809.2(BDNF):c.28C>A (p.Arg10Ser) single nucleotide variant BDNF-related disorder [RCV004745742] Chr11:27701009 [GRCh38]
Chr11:27722556 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.488C>T (p.Thr163Met) single nucleotide variant BDNF-related disorder [RCV004745679] Chr11:27658077 [GRCh38]
Chr11:27679624 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.272C>A (p.Thr91Lys) single nucleotide variant BDNF-related disorder [RCV004745820] Chr11:27658293 [GRCh38]
Chr11:27679840 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.418G>A (p.Val140Met) single nucleotide variant BDNF-related disorder [RCV004745856] Chr11:27658147 [GRCh38]
Chr11:27679694 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15635C>T single nucleotide variant BDNF-related disorder [RCV004746032] Chr11:27674220 [GRCh38]
Chr11:27695767 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.489G>A (p.Thr163=) single nucleotide variant BDNF-related disorder [RCV004746053] Chr11:27658076 [GRCh38]
Chr11:27679623 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-21-15541C>A single nucleotide variant BDNF-related disorder [RCV004746712] Chr11:27674126 [GRCh38]
Chr11:27695673 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-22+764G>A single nucleotide variant BDNF-related disorder [RCV004747564] Chr11:27699400 [GRCh38]
Chr11:27720947 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.547G>A (p.Glu183Lys) single nucleotide variant BDNF-related disorder [RCV004747804] Chr11:27658018 [GRCh38]
Chr11:27679565 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.-21-15602C>T single nucleotide variant BDNF-related disorder [RCV004747876] Chr11:27674187 [GRCh38]
Chr11:27695734 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.537A>G (p.Gln179=) single nucleotide variant BDNF-related disorder [RCV004747866] Chr11:27658028 [GRCh38]
Chr11:27679575 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.-22+777G>T single nucleotide variant BDNF-related disorder [RCV004724323] Chr11:27699387 [GRCh38]
Chr11:27720934 [GRCh37]
Chr11:11p14.1
uncertain significance
GRCh37/hg19 11p14.3-13(chr11:24192701-32455527)x1 copy number loss not provided [RCV004819368] Chr11:24192701..32455527 [GRCh37]
Chr11:11p14.3-13
pathogenic
NM_001709.5(BDNF):c.163G>A (p.Gly55Ser) single nucleotide variant Inborn genetic diseases [RCV004969897] Chr11:27658402 [GRCh38]
Chr11:27679949 [GRCh37]
Chr11:11p14.1
uncertain significance
GRCh37/hg19 11p14.3-12(chr11:22428384-37196643)x1 copy number loss not provided [RCV004819367] Chr11:22428384..37196643 [GRCh37]
Chr11:11p14.3-12
pathogenic
NM_001709.5(BDNF):c.370A>T (p.Met124Leu) single nucleotide variant Inborn genetic diseases [RCV004969895] Chr11:27658195 [GRCh38]
Chr11:27679742 [GRCh37]
Chr11:11p14.1
uncertain significance
GRCh37/hg19 11p15.1-12(chr11:17120358-41424289)x1 copy number loss not provided [RCV004819366] Chr11:17120358..41424289 [GRCh37]
Chr11:11p15.1-12
pathogenic
NM_001709.5(BDNF):c.75C>T (p.Asn25=) single nucleotide variant not provided [RCV005069730] Chr11:27658490 [GRCh38]
Chr11:27680037 [GRCh37]
Chr11:11p14.1
likely benign
NM_001709.5(BDNF):c.293G>A (p.Ser98Asn) single nucleotide variant Inborn genetic diseases [RCV005314318] Chr11:27658272 [GRCh38]
Chr11:27679819 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.331G>C (p.Glu111Gln) single nucleotide variant Inborn genetic diseases [RCV005305802] Chr11:27658234 [GRCh38]
Chr11:27679781 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.221A>C (p.Asp74Ala) single nucleotide variant Inborn genetic diseases [RCV005305805] Chr11:27658344 [GRCh38]
Chr11:27679891 [GRCh37]
Chr11:11p14.1
uncertain significance
NM_001709.5(BDNF):c.321C>T (p.Leu107=) single nucleotide variant Inborn genetic diseases [RCV005305806] Chr11:27658244 [GRCh38]
Chr11:27679791 [GRCh37]
Chr11:11p14.1
likely benign
miRNA Target Status (No longer updated)

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR30Ahsa-miR-30a-3pMirecordsexternal_infoNANA18632683
MIR1-1hsa-miR-1Mirtarbaseexternal_infoLuciferase reporter assayFunctional MTI14697198
MIR22hsa-miR-22-3pMirtarbaseexternal_infoLuciferase reporter assay//MicroarrayFunctional MTI21168126
MIR204hsa-miR-204-5pOncomiRDBexternal_infoNANA23285024

Predicted Target Of
Summary Value
Count of predictions:25467
Count of miRNA genes:1169
Interacting mature miRNAs:1532
Transcripts:ENST00000314915, ENST00000356660, ENST00000395978, ENST00000395980, ENST00000395981, ENST00000395983, ENST00000395986, ENST00000418212, ENST00000420794, ENST00000438929, ENST00000439476, ENST00000525528, ENST00000525950, ENST00000530786, ENST00000530861, ENST00000532997, ENST00000533131, ENST00000533246, ENST00000584049
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
597504797GWAS1600871_Htriglyceride measurement QTL GWAS1600871 (human)3e-10triglyceride amount (VT:0000187)blood triglyceride level (CMO:0000118)112767328827673289Human
1576345LVC1_HLeft ventricular contractility QTL 1 (human)3.93Left ventricular contractility11797076733970767Human
2289313BW388_HBody weight QTL 388 (human)1.570.00356Body fat amountabdominal11443467130434671Human
597336729GWAS1432803_HC-reactive protein measurement QTL GWAS1432803 (human)2e-24C-reactive protein amount (VT:0010036)blood C-reactive protein level (CMO:0003160)112767857827678579Human
597064850GWAS1160924_Hbody mass index QTL GWAS1160924 (human)0.000005body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
597232030GWAS1328104_Hsmoking cessation QTL GWAS1328104 (human)0.000003smoking cessation112767269427672695Human
596955932GWAS1075451_Hinflammatory biomarker measurement, diet measurement QTL GWAS1075451 (human)9e-12inflammatory biomarker measurement, diet measurement112768083627680837Human
597383186GWAS1479260_Hage at menarche QTL GWAS1479260 (human)9e-16estrous cycle trait (VT:0001927)112768083627680837Human
597041052GWAS1137126_Hsnoring measurement QTL GWAS1137126 (human)0.000004sleep behavior trait (VT:0001501)112767269427672695Human
597486486GWAS1582560_Hbody mass index QTL GWAS1582560 (human)7e-63body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112768266227682663Human
597438993GWAS1535067_Hbody mass index QTL GWAS1535067 (human)1e-34body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112768083627680837Human
597030811GWAS1126885_Hsmoking initiation QTL GWAS1126885 (human)1e-11behavior trait (VT:0010442)112767269427672695Human
406891217GWAS540193_Hbody mass index QTL GWAS540193 (human)7e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
597493000GWAS1589074_Hbody mass index QTL GWAS1589074 (human)9e-09body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112765603627656037Human
596987148GWAS1106667_Hbody mass index QTL GWAS1106667 (human)6e-15body mass index112765603927656040Human
597065612GWAS1161686_Hbody mass index QTL GWAS1161686 (human)1e-12body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
597241219GWAS1337293_HC-reactive protein measurement QTL GWAS1337293 (human)1e-18C-reactive protein amount (VT:0010036)blood C-reactive protein level (CMO:0003160)112767857827678579Human
596987145GWAS1106664_Hfat body mass QTL GWAS1106664 (human)1e-08fat body mass112765603927656040Human
407163992GWAS812968_Hage at menarche QTL GWAS812968 (human)3e-11estrous cycle trait (VT:0001927)112767857827678579Human
597411463GWAS1507537_Hage at menopause QTL GWAS1507537 (human)0.0000002estrous cycle trait (VT:0001927)112768083627680837Human
406890974GWAS539950_Hbody mass index QTL GWAS539950 (human)8e-42body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
596966065GWAS1085584_Hbody mass index QTL GWAS1085584 (human)2e-50body mass index112771287327712874Human
597065788GWAS1161862_Hphysical activity measurement, body mass index QTL GWAS1161862 (human)2e-22body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767857827678579Human
407125871GWAS774847_Hsnoring measurement QTL GWAS774847 (human)9e-11sleep behavior trait (VT:0001501)112767269427672695Human
597064743GWAS1160817_Hbody mass index QTL GWAS1160817 (human)1e-11body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767857827678579Human
597504937GWAS1601011_HCOVID-19, obesity QTL GWAS1601011 (human)8e-14eating behavior trait (VT:0001431)112768083627680837Human
596960800GWAS1080319_Hmetabolic syndrome QTL GWAS1080319 (human)5e-54metabolic syndrome112769083427690835Human
597501098GWAS1597172_Htriglyceride measurement QTL GWAS1597172 (human)1e-11triglyceride amount (VT:0000187)blood triglyceride level (CMO:0000118)112767328827673289Human
597339173GWAS1435247_Hpuberty onset measurement QTL GWAS1435247 (human)1e-10time of sexual maturation trait (VT:0001938)112767269427672695Human
596968663GWAS1088182_Hbody mass index QTL GWAS1088182 (human)9e-51body mass index112765836927658370Human
597066964GWAS1163038_Hage at menarche QTL GWAS1163038 (human)0.0000001estrous cycle trait (VT:0001927)112767857827678579Human
597392350GWAS1488424_Htriglyceride measurement QTL GWAS1488424 (human)9e-13triglyceride amount (VT:0000187)blood triglyceride level (CMO:0000118)112767328827673289Human
597399388GWAS1495462_Huric acid measurement QTL GWAS1495462 (human)2e-08blood uric acid amount (VT:0010302)blood uric acid level (CMO:0000501)112767244427672445Human
597467861GWAS1563935_Hfeeling nervous measurement QTL GWAS1563935 (human)3e-09emotion/affect behavior trait (VT:0002572)112767328827673289Human
597064902GWAS1160976_Hbody mass index QTL GWAS1160976 (human)3e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
1559107SCL32_HSerum cholesterol level QTL 32 (human)3.27Lipid levelLDL cholesterol11289243028892430Human
597284172GWAS1380246_HC-reactive protein measurement QTL GWAS1380246 (human)4e-12C-reactive protein amount (VT:0010036)blood C-reactive protein level (CMO:0003160)112767269427672695Human
597064896GWAS1160970_Hphysical activity measurement, body mass index QTL GWAS1160970 (human)0.000001body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
1559104SCL15_HSerum cholesterol level QTL 15 (human)2.60.06Lipid levelhyperlipidemia susceptibility111589236841892368Human
596963278GWAS1082797_Hfat body mass QTL GWAS1082797 (human)1e-32fat body mass112769083427690835Human
1559113SCL31_HSerum cholesterol level QTL 31 (human)3.72Lipid levelLDL cholesterol11289243028892430Human
597041225GWAS1137299_Hsnoring measurement QTL GWAS1137299 (human)9e-10body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767269427672695Human
597500670GWAS1596744_Hbody weight QTL GWAS1596744 (human)1e-11body mass (VT:0001259)body weight (CMO:0000012)112765603627656037Human
597368831GWAS1464905_Hhematocrit QTL GWAS1464905 (human)1e-10erythrocyte morphology trait (VT:0002447)hematocrit (CMO:0000037)112765603627656037Human
596963315GWAS1082834_Hbody mass index QTL GWAS1082834 (human)1e-37body mass index112769083427690835Human
597366003GWAS1462077_Hhemoglobin measurement QTL GWAS1462077 (human)1e-09blood hemoglobin amount (VT:0001588)hemoglobin measurement (CMO:0000508)112765603627656037Human
597614068GWAS1670928_Hsodium measurement QTL GWAS1670928 (human)2e-13blood sodium amount (VT:0001776)blood sodium level (CMO:0000499)112767269427672695Human
597065468GWAS1161542_Hphysical activity measurement, body mass index QTL GWAS1161542 (human)2e-19body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767857827678579Human
596989669GWAS1109188_Hbody mass index QTL GWAS1109188 (human)3e-27body mass index112771287327712874Human
596989668GWAS1109187_Hbody mass index QTL GWAS1109187 (human)4e-56body mass index112765836927658370Human
597064288GWAS1160362_Hphysical activity measurement, body mass index QTL GWAS1160362 (human)2e-21body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767857827678579Human
597015907GWAS1111981_Hcoronary artery disease QTL GWAS1111981 (human)0.000003coronary artery integrity trait (VT:0010746)112768083627680837Human
597427307GWAS1523381_Hurate measurement QTL GWAS1523381 (human)2e-11urate measurementblood uric acid level (CMO:0000501)112767244427672445Human
596953069GWAS1072588_Hbody mass index QTL GWAS1072588 (human)2e-36body mass index112770900927709010Human
597522150GWAS1618224_Hurate measurement QTL GWAS1618224 (human)2e-08urate measurementblood uric acid level (CMO:0000501)112767328827673289Human
597064941GWAS1161015_Hbody mass index QTL GWAS1161015 (human)3e-15body size trait (VT:0100005)body mass index (BMI) (CMO:0000105)112767857827678579Human
596964456GWAS1083975_Hbody mass index QTL GWAS1083975 (human)1e-28body mass index112765603927656040Human
597224676GWAS1320750_HC-reactive protein measurement QTL GWAS1320750 (human)2e-11C-reactive protein amount (VT:0010036)blood C-reactive protein level (CMO:0003160)112767269427672695Human
597455584GWAS1551658_Hinflammatory biomarker measurement, diet measurement QTL GWAS1551658 (human)9e-12eating behavior trait (VT:0001431)food intake measurement (CMO:0000772)112768083627680837Human
407038525GWAS687501_Hrisk-taking behaviour QTL GWAS687501 (human)3e-11exploratory behavior trait (VT:0010471)112767269427672695Human

Markers in Region
D11S4115  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,737,913 - 27,738,101UniSTSGRCh37
Build 361127,694,489 - 27,694,677RGDNCBI36
Celera1127,884,027 - 27,884,221RGD
Cytogenetic Map11p13UniSTS
HuRef1127,436,072 - 27,436,264UniSTS
Marshfield Genetic Map1135.21RGD
Marshfield Genetic Map1135.21UniSTS
Genethon Genetic Map1138.7UniSTS
deCODE Assembly Map1144.48UniSTS
Whitehead-YAC Contig Map11 UniSTS
D11S1270  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,730,319 - 27,730,713UniSTSGRCh37
Build 361127,686,895 - 27,687,289RGDNCBI36
Celera1127,876,432 - 27,876,827RGD
Cytogenetic Map11p13UniSTS
HuRef1127,428,479 - 27,428,874UniSTS
D11S2825  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,709,227 - 27,709,393UniSTSGRCh37
Build 361127,665,803 - 27,665,969RGDNCBI36
Celera1127,855,336 - 27,855,502RGD
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map11p13UniSTS
HuRef1127,407,388 - 27,407,554UniSTS
GDB:197571  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,680,022 - 27,680,600UniSTSGRCh37
Build 361127,636,598 - 27,637,176RGDNCBI36
Celera1127,826,129 - 27,826,707RGD
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map11p13UniSTS
HuRef1127,378,167 - 27,378,745UniSTS
BDNF  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,681,064 - 27,681,285UniSTSGRCh37
GRCh371127,679,498 - 27,680,106UniSTSGRCh37
Build 361127,637,640 - 27,637,861RGDNCBI36
Celera1127,825,605 - 27,826,213UniSTS
Celera1127,827,171 - 27,827,394RGD
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map11p13UniSTS
HuRef1127,379,209 - 27,379,432UniSTS
HuRef1127,377,643 - 27,378,251UniSTS
GeneMap99-GB4 RH Map11106.12UniSTS
BDNF-1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,679,473 - 27,679,755UniSTSGRCh37
Build 361127,636,049 - 27,636,331RGDNCBI36
Celera1127,825,580 - 27,825,862RGD
HuRef1127,377,618 - 27,377,900UniSTS
BDNF_2411  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,678,808 - 27,679,691UniSTSGRCh37
Build 361127,635,384 - 27,636,267RGDNCBI36
Celera1127,824,916 - 27,825,798RGD
HuRef1127,376,954 - 27,377,836UniSTS
D11S4429  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371127,679,106 - 27,679,207UniSTSGRCh37
Build 361127,635,682 - 27,635,783RGDNCBI36
Celera1127,825,213 - 27,825,314RGD
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map11p13UniSTS
HuRef1127,377,251 - 27,377,352UniSTS
Whitehead-YAC Contig Map11 UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
1199 2382 2746 2226 4934 1631 2234 4 533 1288 375 2252 6450 5789 39 3708 826 1724 1589 171

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_011794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143806 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143809 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143812 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001143816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170731 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_170735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011520280 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB038670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB038674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC103796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC104563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF400438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF411339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289853 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY011481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054392 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY442188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY656701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC029795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX751420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ250642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF674517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF674518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF674519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF674520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF674521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689012 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689016 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689018 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF689021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM763820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC855559 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF455346 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF459669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP229412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU177943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU177944 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KU177945 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX964616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KX964617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M37762 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M61181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X60202 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X91251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000314915   ⟹   ENSP00000320002
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,722,058 (-)Ensembl
Ensembl Acc Id: ENST00000356660   ⟹   ENSP00000349084
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,700,455 (-)Ensembl
Ensembl Acc Id: ENST00000395978   ⟹   ENSP00000379302
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,720,723 (-)Ensembl
Ensembl Acc Id: ENST00000395980   ⟹   ENSP00000379304
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,633 (-)Ensembl
Ensembl Acc Id: ENST00000395981   ⟹   ENSP00000379305
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,720,723 (-)Ensembl
Ensembl Acc Id: ENST00000395983   ⟹   ENSP00000379307
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,053 (-)Ensembl
Ensembl Acc Id: ENST00000395986   ⟹   ENSP00000379309
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,699,667 (-)Ensembl
Ensembl Acc Id: ENST00000418212   ⟹   ENSP00000400502
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,700,488 (-)Ensembl
Ensembl Acc Id: ENST00000420794   ⟹   ENSP00000389564
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,053 (-)Ensembl
Ensembl Acc Id: ENST00000438929   ⟹   ENSP00000414303
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,053 (-)Ensembl
Ensembl Acc Id: ENST00000439476   ⟹   ENSP00000389345
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,659,658 (-)Ensembl
Ensembl Acc Id: ENST00000525528   ⟹   ENSP00000437138
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,659,658 (-)Ensembl
Ensembl Acc Id: ENST00000525950   ⟹   ENSP00000432035
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,720,779 (-)Ensembl
Ensembl Acc Id: ENST00000530786   ⟹   ENSP00000433003
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,053 (-)Ensembl
Ensembl Acc Id: ENST00000530861   ⟹   ENSP00000435564
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,700,900 (-)Ensembl
Ensembl Acc Id: ENST00000532997   ⟹   ENSP00000435805
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,719,747 (-)Ensembl
Ensembl Acc Id: ENST00000533131   ⟹   ENSP00000432727
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,699,667 (-)Ensembl
Ensembl Acc Id: ENST00000533246   ⟹   ENSP00000432376
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,700,488 (-)Ensembl
Ensembl Acc Id: ENST00000584049
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1127,654,893 - 27,701,633 (-)Ensembl
RefSeq Acc Id: NM_001143805   ⟹   NP_001137277
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,720,779 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,741,249 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,861,210 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143806   ⟹   NP_001137278
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,720,779 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,741,249 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,861,210 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143807   ⟹   NP_001137279
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,719,566 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,740,217 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,859,997 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143808   ⟹   NP_001137280
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,701,053 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,721,513 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,841,478 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143809   ⟹   NP_001137281
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,701,053 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,721,513 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,841,478 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143810   ⟹   NP_001137282
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,701,053 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,721,513 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,841,478 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143811   ⟹   NP_001137283
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,701,053 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,721,513 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,841,478 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143812   ⟹   NP_001137284
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,700,900 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,721,360 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,841,325 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143813   ⟹   NP_001137285
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,700,455 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,720,774 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,840,883 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143814   ⟹   NP_001137286
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,700,455 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,720,774 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,840,883 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001143816   ⟹   NP_001137288
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,659,658 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,679,939 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,800,065 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001709   ⟹   NP_001700
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,700,455 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,678,552 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,720,774 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,840,883 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170731   ⟹   NP_733927
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,722,030 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,699,872 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,742,527 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,862,460 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170732   ⟹   NP_733928
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,720,779 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,698,846 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,741,249 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,861,210 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170733   ⟹   NP_733929
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,701,621 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,679,729 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,722,093 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,842,046 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170734   ⟹   NP_733930
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,699,667 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,677,756 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,719,953 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,840,095 (-)NCBI
Sequence:
RefSeq Acc Id: NM_170735   ⟹   NP_733931
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,654,893 - 27,659,658 (-)NCBI
GRCh371127,676,440 - 27,743,605 (-)ENTREZGENE
Build 361127,633,016 - 27,637,249 (-)NCBI Archive
HuRef1127,374,586 - 27,441,772 (-)ENTREZGENE
CHM1_11127,675,184 - 27,679,939 (-)NCBI
T2T-CHM13v2.01127,795,301 - 27,800,065 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001137277 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137278 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137279 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137280 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137281 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137282 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137283 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137284 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137285 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137286 (Get FASTA)   NCBI Sequence Viewer  
  NP_001137288 (Get FASTA)   NCBI Sequence Viewer  
  NP_001700 (Get FASTA)   NCBI Sequence Viewer  
  NP_733927 (Get FASTA)   NCBI Sequence Viewer  
  NP_733928 (Get FASTA)   NCBI Sequence Viewer  
  NP_733929 (Get FASTA)   NCBI Sequence Viewer  
  NP_733930 (Get FASTA)   NCBI Sequence Viewer  
  NP_733931 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA51820 (Get FASTA)   NCBI Sequence Viewer  
  AAA69805 (Get FASTA)   NCBI Sequence Viewer  
  AAA96140 (Get FASTA)   NCBI Sequence Viewer  
  AAG47514 (Get FASTA)   NCBI Sequence Viewer  
  AAH29795 (Get FASTA)   NCBI Sequence Viewer  
  AAK92487 (Get FASTA)   NCBI Sequence Viewer  
  AAL23557 (Get FASTA)   NCBI Sequence Viewer  
  AAL23558 (Get FASTA)   NCBI Sequence Viewer  
  AAL23559 (Get FASTA)   NCBI Sequence Viewer  
  AAL23560 (Get FASTA)   NCBI Sequence Viewer  
  AAL23561 (Get FASTA)   NCBI Sequence Viewer  
  AAL23562 (Get FASTA)   NCBI Sequence Viewer  
  AAL23563 (Get FASTA)   NCBI Sequence Viewer  
  AAL23564 (Get FASTA)   NCBI Sequence Viewer  
  AAL23565 (Get FASTA)   NCBI Sequence Viewer  
  AAL23571 (Get FASTA)   NCBI Sequence Viewer  
  AAO15434 (Get FASTA)   NCBI Sequence Viewer  
  AAR14686 (Get FASTA)   NCBI Sequence Viewer  
  AAT74399 (Get FASTA)   NCBI Sequence Viewer  
  ABB51155 (Get FASTA)   NCBI Sequence Viewer  
  ABS29021 (Get FASTA)   NCBI Sequence Viewer  
  ABS29022 (Get FASTA)   NCBI Sequence Viewer  
  ABS29023 (Get FASTA)   NCBI Sequence Viewer  
  ABS29024 (Get FASTA)   NCBI Sequence Viewer  
  ABS29025 (Get FASTA)   NCBI Sequence Viewer  
  ABS32249 (Get FASTA)   NCBI Sequence Viewer  
  ABS32250 (Get FASTA)   NCBI Sequence Viewer  
  ABS32251 (Get FASTA)   NCBI Sequence Viewer  
  ABS32252 (Get FASTA)   NCBI Sequence Viewer  
  ABS32253 (Get FASTA)   NCBI Sequence Viewer  
  ABS32254 (Get FASTA)   NCBI Sequence Viewer  
  ABS32255 (Get FASTA)   NCBI Sequence Viewer  
  ABS32256 (Get FASTA)   NCBI Sequence Viewer  
  ABS32257 (Get FASTA)   NCBI Sequence Viewer  
  ABS32258 (Get FASTA)   NCBI Sequence Viewer  
  ABS32259 (Get FASTA)   NCBI Sequence Viewer  
  ABS32260 (Get FASTA)   NCBI Sequence Viewer  
  ABS32261 (Get FASTA)   NCBI Sequence Viewer  
  AGR50950 (Get FASTA)   NCBI Sequence Viewer  
  AKB90516 (Get FASTA)   NCBI Sequence Viewer  
  ALQ33401 (Get FASTA)   NCBI Sequence Viewer  
  ALQ33402 (Get FASTA)   NCBI Sequence Viewer  
  ALQ33403 (Get FASTA)   NCBI Sequence Viewer  
  BAB55545 (Get FASTA)   NCBI Sequence Viewer  
  BAB55546 (Get FASTA)   NCBI Sequence Viewer  
  BAB55547 (Get FASTA)   NCBI Sequence Viewer  
  BAB55548 (Get FASTA)   NCBI Sequence Viewer  
  BAB55549 (Get FASTA)   NCBI Sequence Viewer  
  BAF82452 (Get FASTA)   NCBI Sequence Viewer  
  BAF82542 (Get FASTA)   NCBI Sequence Viewer  
  CAA42761 (Get FASTA)   NCBI Sequence Viewer  
  CAA62632 (Get FASTA)   NCBI Sequence Viewer  
  EAW68274 (Get FASTA)   NCBI Sequence Viewer  
  EAW68275 (Get FASTA)   NCBI Sequence Viewer  
  EAW68276 (Get FASTA)   NCBI Sequence Viewer  
  EAW68277 (Get FASTA)   NCBI Sequence Viewer  
  EAW68278 (Get FASTA)   NCBI Sequence Viewer  
  EAW68279 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000320002
  ENSP00000320002.6
  ENSP00000349084
  ENSP00000349084.4
  ENSP00000379302
  ENSP00000379302.3
  ENSP00000379305
  ENSP00000379305.3
  ENSP00000379307
  ENSP00000379307.3
  ENSP00000379309
  ENSP00000379309.2
  ENSP00000389345
  ENSP00000389345.2
  ENSP00000400502
  ENSP00000400502.1
  ENSP00000414303
  ENSP00000414303.1
  ENSP00000432035
  ENSP00000432035.1
  ENSP00000432376
  ENSP00000432376.1
  ENSP00000432727.1
  ENSP00000435564
  ENSP00000435564.1
  ENSP00000435805
  ENSP00000435805.1
  ENSP00000437138
  ENSP00000437138.1
GenBank Protein P23560 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_733927   ⟸   NM_170731
- Peptide Label: isoform b precursor
- UniProtKB: A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137277   ⟸   NM_001143805
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137278   ⟸   NM_001143806
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_733928   ⟸   NM_170732
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137279   ⟸   NM_001143807
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_733929   ⟸   NM_170733
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137280   ⟸   NM_001143808
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137281   ⟸   NM_001143809
- Peptide Label: isoform d precursor
- UniProtKB: P23560 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001137282   ⟸   NM_001143810
- Peptide Label: isoform e
- UniProtKB: P23560 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001137283   ⟸   NM_001143811
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137284   ⟸   NM_001143812
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137285   ⟸   NM_001143813
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001700   ⟸   NM_001709
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001137286   ⟸   NM_001143814
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_733930   ⟸   NM_170734
- Peptide Label: isoform c precursor
- UniProtKB: P23560 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001137288   ⟸   NM_001143816
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_733931   ⟸   NM_170735
- Peptide Label: isoform a preproprotein
- UniProtKB: Q9BYY7 (UniProtKB/Swiss-Prot),   Q6YNR3 (UniProtKB/Swiss-Prot),   Q6YNR2 (UniProtKB/Swiss-Prot),   Q6DN19 (UniProtKB/Swiss-Prot),   Q598Q1 (UniProtKB/Swiss-Prot),   D3DQZ2 (UniProtKB/Swiss-Prot),   A7LA92 (UniProtKB/Swiss-Prot),   A7LA85 (UniProtKB/Swiss-Prot),   Q9UC24 (UniProtKB/Swiss-Prot),   P23560 (UniProtKB/Swiss-Prot),   A0A0E3SU01 (UniProtKB/TrEMBL),   A0A0S2Z3E7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000414303   ⟸   ENST00000438929
Ensembl Acc Id: ENSP00000389345   ⟸   ENST00000439476
Ensembl Acc Id: ENSP00000433003   ⟸   ENST00000530786
Ensembl Acc Id: ENSP00000435564   ⟸   ENST00000530861
Ensembl Acc Id: ENSP00000435805   ⟸   ENST00000532997
Ensembl Acc Id: ENSP00000432376   ⟸   ENST00000533246
Ensembl Acc Id: ENSP00000432727   ⟸   ENST00000533131
Ensembl Acc Id: ENSP00000400502   ⟸   ENST00000418212
Ensembl Acc Id: ENSP00000320002   ⟸   ENST00000314915
Ensembl Acc Id: ENSP00000432035   ⟸   ENST00000525950
Ensembl Acc Id: ENSP00000437138   ⟸   ENST00000525528
Ensembl Acc Id: ENSP00000349084   ⟸   ENST00000356660
Ensembl Acc Id: ENSP00000389564   ⟸   ENST00000420794
Ensembl Acc Id: ENSP00000379302   ⟸   ENST00000395978
Ensembl Acc Id: ENSP00000379309   ⟸   ENST00000395986
Ensembl Acc Id: ENSP00000379307   ⟸   ENST00000395983
Ensembl Acc Id: ENSP00000379304   ⟸   ENST00000395980
Ensembl Acc Id: ENSP00000379305   ⟸   ENST00000395981
Protein Domains
Nerve growth factor-related

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P23560-F1-model_v2 AlphaFold P23560 1-247 view protein structure

Promoters
RGD ID:6788516
Promoter ID:HG_KWN:12523
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid
Transcripts:ENST00000395983,   NM_001143808,   NM_001143809,   NM_001143810,   NM_001143811,   NM_001143812,   NM_001143813,   NM_001143814,   NM_001709,   NM_170734
Position:
Human AssemblyChrPosition (strand)Source
Build 361127,678,349 - 27,678,849 (-)MPROMDB
RGD ID:7219899
Promoter ID:EPDNEW_H15695
Type:initiation region
Name:BDNF_1
Description:brain derived neurotrophic factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15696  EPDNEW_H15697  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,700,455 - 27,700,515EPDNEW
RGD ID:7219901
Promoter ID:EPDNEW_H15696
Type:initiation region
Name:BDNF_3
Description:brain derived neurotrophic factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15695  EPDNEW_H15697  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,701,621 - 27,701,681EPDNEW
RGD ID:7219903
Promoter ID:EPDNEW_H15697
Type:single initiation site
Name:BDNF_2
Description:brain derived neurotrophic factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H15695  EPDNEW_H15696  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381127,719,565 - 27,719,625EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1033 AgrOrtholog
COSMIC BDNF COSMIC
Ensembl Genes ENSG00000176697 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000314915 ENTREZGENE
  ENST00000314915.6 UniProtKB/Swiss-Prot
  ENST00000356660 ENTREZGENE
  ENST00000356660.9 UniProtKB/Swiss-Prot
  ENST00000395978 ENTREZGENE
  ENST00000395978.7 UniProtKB/Swiss-Prot
  ENST00000395981 ENTREZGENE
  ENST00000395981.7 UniProtKB/Swiss-Prot
  ENST00000395983 ENTREZGENE
  ENST00000395983.7 UniProtKB/Swiss-Prot
  ENST00000395986 ENTREZGENE
  ENST00000395986.6 UniProtKB/Swiss-Prot
  ENST00000418212 ENTREZGENE
  ENST00000418212.5 UniProtKB/Swiss-Prot
  ENST00000438929 ENTREZGENE
  ENST00000438929.5 UniProtKB/Swiss-Prot
  ENST00000439476 ENTREZGENE
  ENST00000439476.6 UniProtKB/Swiss-Prot
  ENST00000525528 ENTREZGENE
  ENST00000525528.1 UniProtKB/Swiss-Prot
  ENST00000525950 ENTREZGENE
  ENST00000525950.5 UniProtKB/Swiss-Prot
  ENST00000530861 ENTREZGENE
  ENST00000530861.5 UniProtKB/Swiss-Prot
  ENST00000532997 ENTREZGENE
  ENST00000532997.5 UniProtKB/Swiss-Prot
  ENST00000533131.5 UniProtKB/Swiss-Prot
  ENST00000533246 ENTREZGENE
  ENST00000533246.5 UniProtKB/Swiss-Prot
  ENST00000584049 ENTREZGENE
Gene3D-CATH 2.10.90.10 UniProtKB/Swiss-Prot
GTEx ENSG00000176697 GTEx
HGNC ID HGNC:1033 ENTREZGENE
Human Proteome Map BDNF Human Proteome Map
InterPro Brain-der_neurotrophic_factor UniProtKB/Swiss-Prot
  Cystine-knot_cytokine UniProtKB/Swiss-Prot
  Nerve_growth_factor-like UniProtKB/Swiss-Prot
  Nerve_growth_factor-rel UniProtKB/Swiss-Prot
  Nerve_growth_factor_CS UniProtKB/Swiss-Prot
KEGG Report hsa:627 UniProtKB/Swiss-Prot
NCBI Gene 627 ENTREZGENE
OMIM 113505 OMIM
PANTHER PTHR11589 UniProtKB/Swiss-Prot
  PTHR11589:SF3 UniProtKB/Swiss-Prot
Pfam NGF UniProtKB/Swiss-Prot
PharmGKB BDNF RGD
  PA31891 PharmGKB
PIRSF NGF UniProtKB/Swiss-Prot
PRINTS BDNFACTOR UniProtKB/Swiss-Prot
  NGF UniProtKB/Swiss-Prot
PROSITE NGF_1 UniProtKB/Swiss-Prot
  NGF_2 UniProtKB/Swiss-Prot
SMART NGF UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57501 UniProtKB/Swiss-Prot
UniProt A0A0E3SU01 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z3E7 ENTREZGENE, UniProtKB/TrEMBL
  A0A0S2Z3M9_HUMAN UniProtKB/TrEMBL
  A7LA85 ENTREZGENE
  A7LA92 ENTREZGENE
  BDNF_HUMAN UniProtKB/Swiss-Prot
  D3DQZ2 ENTREZGENE
  E9PMP3_HUMAN UniProtKB/TrEMBL
  P23560 ENTREZGENE
  Q304R1_HUMAN UniProtKB/TrEMBL
  Q598Q1 ENTREZGENE
  Q6DN19 ENTREZGENE
  Q6T2C9_HUMAN UniProtKB/TrEMBL
  Q6YNR1_HUMAN UniProtKB/TrEMBL
  Q6YNR2 ENTREZGENE
  Q6YNR3 ENTREZGENE
  Q9BYY7 ENTREZGENE
  Q9UC24 ENTREZGENE
UniProt Secondary A7LA85 UniProtKB/Swiss-Prot
  A7LA92 UniProtKB/Swiss-Prot
  D3DQZ2 UniProtKB/Swiss-Prot
  Q598Q1 UniProtKB/Swiss-Prot
  Q6DN19 UniProtKB/Swiss-Prot
  Q6YNR2 UniProtKB/Swiss-Prot
  Q6YNR3 UniProtKB/Swiss-Prot
  Q9BYY7 UniProtKB/Swiss-Prot
  Q9UC24 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-07 BDNF  brain derived neurotrophic factor  BDNF  brain-derived neurotrophic factor  Symbol and/or name change 5135510 APPROVED